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methoxsalen and Hand Dermatoses

methoxsalen has been researched along with Hand Dermatoses in 26 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Hand Dermatoses: Skin diseases involving the HANDS.

Research Excerpts

ExcerptRelevanceReference
"Topical methoxsalen photochemotherapy has been assessed in 22 patients suffering from recalcitrant palmoplantar pustulosis or psoriasis predominantly involving the hands and feet."9.04Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis. ( Black, MM; Harper, JI; Ralfs, IG; Wilkinson, JD, 1979)
"Fourteen patients with chronic plaque-type psoriasis involving the palms and soles and 14 patients with palmoplantar vesiculopustular dermatosis, including three cases of localized pustular psoriasis, were treated with topical application of methoxsalen, followed by exposure to long-wave ultraviolet energy (topical PUVA)."7.66Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light. ( Abel, EA; Farber, EM; Goldberg, LH, 1980)
"Topical methoxsalen photochemotherapy has been assessed in 22 patients suffering from recalcitrant palmoplantar pustulosis or psoriasis predominantly involving the hands and feet."5.04Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis. ( Black, MM; Harper, JI; Ralfs, IG; Wilkinson, JD, 1979)
"Fourteen patients with chronic plaque-type psoriasis involving the palms and soles and 14 patients with palmoplantar vesiculopustular dermatosis, including three cases of localized pustular psoriasis, were treated with topical application of methoxsalen, followed by exposure to long-wave ultraviolet energy (topical PUVA)."3.66Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light. ( Abel, EA; Farber, EM; Goldberg, LH, 1980)
" The range of maximum UVA dosage per treatment was 3."1.28Palmoplantar psoriasis: experience with 8-methoxypsoralen soaks plus ultraviolet A with the use of a high-output metal halide device. ( Coleman, WR; David, M; Halder, RM; Lowe, NJ, 1989)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's9 (34.62)18.2507
2000's5 (19.23)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naasan, H1
Dawe, RS1
Ibbotson, SH1
van Coevorden, AM2
Kamphof, WG1
van Sonderen, E1
Bruynzeel, DP1
Coenraads, PJ2
Schiener, R1
Gottlöber, P1
Müller, B1
Williams, S1
Pillekamp, H1
Peter, RU2
Kerscher, M3
Engin, B1
Oguz, O1
Hofer, A1
Fink-Puches, R1
Kerl, H1
Quehenberger, F1
Wolf, P1
Paul, R1
Jansén, CT1
Abel, EA1
Goldberg, LH1
Farber, EM1
Hawk, JL1
Grice, PL1
Korffmacher, H1
Hartwig, R1
Matthes, U1
Dirschka, T1
Albassam, A1
Weindorf, N1
Altmeyer, P2
Abramowitz, AI1
Resnik, KS1
Cohen, KR1
Schempp, CM1
Müller, H1
Czech, W1
Schöpf, E1
Simon, JC1
Gritiyarangsan, P1
Sukhum, A1
Tresukosol, P1
Kullavanijaya, P1
Shephard, SE1
Schregenberger, N1
Dummer, R1
Panizzon, RG1
Behrens, S2
von Kobyletzki, G1
Gruss, C1
Reuther, T1
Grundmann-Kollmann, M1
Taylor, CR1
Baron, ED1
Murray, D1
Warin, AP1
Wilkinson, JD1
Ralfs, IG1
Harper, JI1
Black, MM1
Morison, WL1
Parrish, JA1
Fitzpatrick, TB1
Menné, T1
Mizuno, N2
Nakanishi, A1
Uematsu, S2
Kobayashi, Y1
Suzuki, K1
Ono, M1
Coleman, WR1
Lowe, NJ1
David, M1
Halder, RM1
Lassus, A1
Lauharanta, J1
Eskelinen, A1
Zaynoun, S1
Abi Ali, L1
Tenekjian, K1
Kurban, A1

Trials

9 trials available for methoxsalen and Hand Dermatoses

ArticleYear
Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy.
    Archives of dermatology, 2004, Volume: 140, Issue:12

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Baths; Capsules; Chronic Disease; Eczema; Female

2004
PUVA-gel vs. PUVA-bath therapy for severe recalcitrant palmoplantar dermatoses. A randomized, single-blinded prospective study.
    Photodermatology, photoimmunology & photomedicine, 2005, Volume: 21, Issue:2

    Topics: Adult; Aged; Baths; Eczema; Female; Foot Dermatoses; Gels; Hand Dermatoses; Humans; Male; Methoxsale

2005
Paired comparison of bathwater versus oral delivery of 8-methoxypsoralen in psoralen plus ultraviolet: A therapy for chronic palmoplantar psoriasis.
    Photodermatology, photoimmunology & photomedicine, 2006, Volume: 22, Issue:1

    Topics: Adult; Aged; Baths; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged

2006
Topical PUVA therapy for chronic hand eczema.
    The Journal of dermatology, 1998, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chronic Disease; Eczema; Female; Hand Dermatoses;

1998
PUVA-bath photochemotherapy (PUVA-soak therapy) of recalcitrant dermatoses of the palms and soles.
    Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:2

    Topics: Administration, Cutaneous; Adult; Combined Modality Therapy; Female; Foot Dermatoses; Hand Dermatose

1999
Treatment of severe recalcitrant dermatoses of the palms and soles with PUVA-bath versus PUVA-cream therapy.
    Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Eczema; Emulsions; Female; Foot Dermatoses; Hand Dermatoses;

1999
Photochemotherapy for persistent palmoplantar pustulosis (PPP) [proceedings].
    The British journal of dermatology, 1979, Volume: 101 Suppl 17

    Topics: Administration, Oral; Clinical Trials as Topic; Foot Dermatoses; Hand Dermatoses; Humans; Methoxsale

1979
Topical methoxsalen photochemotherapy in the treatment of palmoplantar pustulosis and psoriasis.
    Acta dermato-venereologica. Supplementum, 1979, Volume: 59, Issue:85

    Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Female; Foot Dermatoses; Hand Dermat

1979
The effect of etretinate compared with different regimens of PUVA in the treatment of persistent palmoplantar pustulosis.
    The British journal of dermatology, 1985, Volume: 112, Issue:4

    Topics: Chronic Disease; Etretinate; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Mi

1985

Other Studies

17 other studies available for methoxsalen and Hand Dermatoses

ArticleYear
Efficacy of localized hand and foot phototherapy: a review of patients treated in a teaching hospital setting.
    Clinical and experimental dermatology, 2019, Volume: 44, Issue:3

    Topics: 5-Methoxypsoralen; Foot Dermatoses; Hand Dermatoses; Hospitals, Teaching; Humans; Methoxsalen; Photo

2019
Evaluation of time-dependent response to psoralen plus UVA (PUVA) treatment with topical 8-methoxypsoralen (8-MOP) gel in palmoplantar dermatoses.
    International journal of dermatology, 2005, Volume: 44, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Aged; Female; Foot Dermatoses; Gels; Hand Dermatoses; Hu

2005
Suppression of palmoplantar pustulosis symptoms with oral 8-methoxypsoralen and high-intensity UVA irradiation.
    Dermatologica, 1983, Volume: 167, Issue:5

    Topics: Administration, Oral; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Ag

1983
Treatment of palmoplantar psoriasis with topical methoxsalen plus long-wave ultraviolet light.
    Archives of dermatology, 1980, Volume: 116, Issue:11

    Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Foot Dermatoses; Hand Dermatoses; Humans; Male;

1980
The efficacy of localized PUVA therapy for chronic hand and foot dermatoses.
    Clinical and experimental dermatology, 1994, Volume: 19, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Chronic Disease; Fe

1994
Contact allergy to 8-methoxypsoralen.
    Contact dermatitis, 1994, Volume: 30, Issue:5

    Topics: Adult; Dermatitis, Allergic Contact; Dermatitis, Phototoxic; Drug Eruptions; Eczema, Dyshidrotic; Fe

1994
Margarita photodermatitis.
    The New England journal of medicine, 1993, Mar-25, Volume: 328, Issue:12

    Topics: Adult; Fruit; Hand Dermatoses; Humans; Male; Methoxsalen; Photosensitivity Disorders

1993
Treatment of chronic palmoplantar eczema with local bath-PUVA therapy.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:5 Pt 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baths; Chronic Disease; Eczema; Female; Foot Dermatoses;

1997
Comparison of 8-MOP aqueous bath and 8-MOP ethanolic lotion (Meladinine) in local PUVA therapy.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:1

    Topics: Administration, Cutaneous; Adult; Baths; Dose-Response Relationship, Drug; Female; Foot Dermatoses;

1998
Hand and foot PUVA soaks: an audit of the Massachusetts General Hospital's experience from 1994 to 1998.
    Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Foot Dermatoses; Hand Dermatoses; Humans;

1999
Severe influenzalike symptoms associated with methoxsalen photochemotherapy.
    Archives of dermatology, 2002, Volume: 138, Issue:6

    Topics: Eczema; Follow-Up Studies; Hand Dermatoses; Humans; Influenza, Human; Male; Methoxsalen; Middle Aged

2002
Oral methoxsalen photochemotherapy of recalcitrant dermatoses of the palms and soles.
    The British journal of dermatology, 1978, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Aged; Eczema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Methoxsalen; Midd

1978
[Treatment with 8-methoxypsoralen and long-wave ultraviolet light. Psoriasis on the palms and soles and pustulosis palmaris and plantaris].
    Ugeskrift for laeger, 1976, Nov-29, Volume: 138, Issue:49

    Topics: Adult; Aged; Drug Evaluation; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; M

1976
[8-Methoxypsoralen photochemotherapy of palmo-plantar pustulosis (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1976, Sep-10, Volume: 86, Issue:10

    Topics: Adult; Aged; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged; Suppu

1976
[8-Methoxypsoralen phototherapy of pustulosis palmaris et plantaris (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1975, Volume: 85, Issue:10

    Topics: Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged; Ultraviolet Therap

1975
Palmoplantar psoriasis: experience with 8-methoxypsoralen soaks plus ultraviolet A with the use of a high-output metal halide device.
    Journal of the American Academy of Dermatology, 1989, Volume: 20, Issue:6

    Topics: Adult; Aged; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Middle Aged; Psori

1989
The bergapten content of garden parsley and its significance in causing cutaneous photosensitization.
    Clinical and experimental dermatology, 1985, Volume: 10, Issue:4

    Topics: 5-Methoxypsoralen; Food; Hand Dermatoses; Humans; Magnoliopsida; Methoxsalen; Photosensitivity Disor

1985