methoxsalen has been researched along with Erythroderma, Sezary in 11 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine patients with stages 2 or 3 mycosis fungoides (MF) and one with Sézary's syndrome were treated with oral methoxsalen and long-wave ultraviolet light." | 3.66 | Photochemotherapy for mycosis fungoides: a clinical and histological study. ( Cripps, DJ; Dufton, PA; Lowe, NJ; Vickers, CF, 1979) |
| "Mycosis fungoides is a cutaneously-derived malignant lymphoma which, without effective treatment, may run an unrelenting, rapidly lethal course." | 1.26 | Mycosis fungoides: clinical and therapeutic review. ( Basler, RS; Lynch, PJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zic, JA | 1 |
| Vagace, JM | 1 |
| Gervasini, G | 1 |
| Morais, F | 1 |
| Benitez, J | 1 |
| Alonso, N | 1 |
| de Argila, D | 1 |
| Arranz, I | 1 |
| Bajo, R | 1 |
| Marschalkó, M | 1 |
| Knobler, R | 1 |
| Soós, G | 1 |
| Berecz, M | 1 |
| Pálóczy, K | 1 |
| Rácz, I | 1 |
| Jacolot, A | 1 |
| Tod, M | 1 |
| Heudes, AM | 1 |
| Petitjean, O | 1 |
| Laroche, L | 1 |
| Duvic, M | 1 |
| Hester, JP | 1 |
| Lemak, NA | 1 |
| Shephard, SE | 1 |
| Zogg, M | 1 |
| Burg, G | 1 |
| Panizzon, RG | 1 |
| Minna, JD | 1 |
| Roenigk, HH | 2 |
| Glatstein, E | 1 |
| Basler, RS | 1 |
| Lynch, PJ | 1 |
| Lowe, NJ | 1 |
| Cripps, DJ | 1 |
| Dufton, PA | 1 |
| Vickers, CF | 1 |
| Fossel, ET | 1 |
| Fletcher, JG | 1 |
| McDonagh, J | 1 |
| Hui, KK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label, Single-cohort, and Single-center Phase II Study Evaluating Tumor-specific Immunity After Extracorporeal Photopheresis in Patients With Sézary Syndrome at Single-cell Resolution[NCT05157581] | 15 participants (Anticipated) | Observational | 2023-04-04 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methoxsalen and Erythroderma, Sezary
| Article | Year |
|---|---|
Extracorporeal Photopheresis in the Treatment of Mycosis Fungoides and Sézary Syndrome.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Humans; Immunomodulation; Methoxsalen; Mycosis Fungoi | 2015 |
Report of the Committee on Therapy for Mycosis Fungoides and Sézary Syndrome.
Topics: Administration, Topical; Antineoplastic Agents; Drug Therapy, Combination; Humans; Methoxsalen; Myco | 1979 |
1 trial available for methoxsalen and Erythroderma, Sezary
| Article | Year |
|---|---|
Monitoring of 8-methoxypsoralen during extracorporeal photochemotherapy: evidence for a "first-dose" effect.
Topics: Adult; Aged; Aged, 80 and over; Blood Cell Count; Chromatography, High Pressure Liquid; Extracorpore | 1996 |
8 other studies available for methoxsalen and Erythroderma, Sezary
| Article | Year |
|---|---|
Retinal toxic reactions following photopheresis.
Topics: Chorioretinitis; Humans; Male; Methoxsalen; Middle Aged; Photopheresis; Photosensitizing Agents; Sez | 2007 |
[Extracorporeal photopheresis in the therapy of Sézary syndrome].
Topics: Administration, Oral; Blood Component Transfusion; Chlorambucil; Combined Modality Therapy; Humans; | 1993 |
Photopheresis therapy for cutaneous T-cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Dermatitis, Exfoliative; Female; Follow-Up Studies; Forecasting; Hum | 1996 |
Measurement of 5-methoxypsoralen and 8-methoxypsoralen in saliva of PUVA patients as a noninvasive, clinically relevant alternative to monitoring in blood.
Topics: 5-Methoxypsoralen; Adult; Feasibility Studies; Female; Humans; Male; Methoxsalen; Middle Aged; Osmol | 1999 |
Mycosis fungoides: clinical and therapeutic review.
Topics: Humans; Lymphoma; Mechlorethamine; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Sezary Syndrom | 1979 |
Photochemotherapy for mycosis fungoides: long-term followup study.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Precancerous Conditions; Remission, Spont | 1979 |
Photochemotherapy for mycosis fungoides: a clinical and histological study.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; R | 1979 |
Selective cytotoxicity of low-density lipoprotein to helper T cells of cutaneous T-cell lymphoma after photoperoxidation with 8-methoxypsoralen.
Topics: Cell Survival; Humans; Lipid Peroxidation; Lipoproteins, LDL; Methoxsalen; Photochemotherapy; Sezary | 1991 |