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methoxsalen and Erythema

methoxsalen has been researched along with Erythema in 69 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"Limited data exist in the literature concerning the characteristics of erythema following psoralen UV-A (PUVA) treatment using topical methoxsalen."7.72The time course of topical PUVA erythema following 15- and 5-minute methoxsalen immersion. ( Dawe, RS; Ferguson, J; Ibbotson, SH; Kwok, YK; Man, I, 2003)
"We compared the characteristics of psoralen and ultraviolet A (PUVA) erythema in skin photosensitized by bath or oral methoxsalen in 20 subjects."7.72An intraindividual study of the characteristics of erythema induced by bath and oral methoxsalen photochemotherapy and narrowband ultraviolet B. ( Dawe, RS; Ferguson, J; Ibbotson, SH; Man, I, 2003)
"There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen) after ingestion of the standard dose used in photochemotherapy (psoralen plus ultraviolet A)."5.31The effect of methoxsalen dose on ultraviolet-A-induced erythema. ( Dawe, RS; Farr, PM; Ibbotson, SH, 2001)
"Successful results have been reported for bath-psoralens plus ultraviolet A (PUVA) treatment of psoriasis with the use of either a low-sensitizing psoralen (methoxsalen) or a high-sensitizing psoralen (trioxsalen), but no evidence has been presented that phototoxicity would be a prerequisite for antipsoriatic activity of these treatments."5.06Antipsoriatic, erythematogenic, and Langerhans cell marker depleting effect of bath-psoralens plus ultraviolet A treatment. Comparison of 8-methoxypsoralen and trimethylpsoralen photosensitization. ( Jansén, CT; Koulu, LM, 1988)
"Because heat has been reported to influence adversely short- and long-term ultraviolet (UV)-radiation-induced skin damage in animals, we investigated the short-term effects of infrared radiation on sunburn and on phototoxic reactions to topical methoxsalen and anthracene in human volunteers."5.05The influence of infrared radiation on short-term ultraviolet-radiation-induced injuries. ( Kaidbey, KH; Kligman, AM; Witkowski, TA, 1982)
"5-Methoxypsoralen (5-MOP) (Psoraderm 5) tablets obtained from France and 5-MOP micronized in capsules (manufactured in our pharmacy department) were administered to seven psoriasis patients in a 1."3.67Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen. ( Cormane, RH; Siddiqui, AH; Stolk, LM; Westerhof, W, 1985)
"Threshold erythema was unaffected by ingestion of a 200-g portion of parsnip."1.34Can dietary furanocoumarin ingestion enhance the erythemal response during high-dose UVA1 therapy? ( Beattie, PE; Ferguson, J; Ibbotson, SH; Smith, G; Wilkie, MJ, 2007)
"We sought to determine the time-course and dose-response characteristics of erythema induced by topical TMP, and to compare these parameters with those for topical 8-methoxypsoralen (MOP) within patients."1.32An intraindividual comparative study of psoralen-UVA erythema induced by bath 8-methoxypsoralen and 4, 5', 8-trimethylpsoralen. ( Dawe, RS; Ferguson, J; Ibbotson, SH; Man, I; McKinlay, J, 2003)
" However, the mean slope of erythema dose-response on the 15-min treated side was significantly steeper than on the 5-min treated side, 0."1.31Reduction in 8-methoxypsoralen immersion time alters the erythemal response to bath PUVA. ( Azurdia, RM; Dean, MP; Rhodes, LE, 2000)
"Histopathology revealed skin phototoxicity of compounds which lacked erythemogenic activity by visual scoring."1.30Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin. ( Conconi, MT; Montesi, F; Parnigotto, PP, 1998)
" Observations on the time-course and dose-response characteristics of PUVA erythema suggest that larger doses of UVA could be used safely, provided that the frequency of PUVA treatment is reduced."1.29Response of psoriasis to twice weekly PUVA. ( Farr, PM; Sakuntabhai, A; Sharpe, GR, 1993)
" The erythema responses were judged visually, and also measured using a reflectance instrument in order to construct dose-response curves."1.29PUVA erythemal sensitivity depends on plasma psoralen concentration and UVA sensitivity. ( Diffey, BL; Farr, PM; Sakuntabhai, A, 1993)
"Erythema was graded visually."1.28Photoinduced cutaneous inflammatory response by psoralens. ( Haberman, HF; Kumar, JR; Menon, IA; Ranadive, NS, 1992)
" The resulting erythema was measured objectively 72 h after irradiation and dose-response curves for psoralen-UVA erythema were constructed."1.28The relationship between plasma psoralen concentration and psoralen-UVA erythema. ( Cox, NH; Diffey, BL; Farr, PM; Fisher, C; Mclelland, J, 1991)
" The dose-response curve is steeper, with blistering reactions occurring in some subjects after as little as three to four times the minimum phototoxic dose of UV radiation at 320-400 nm (UVA)."1.27Cutaneous phototoxicity due to psoralens. ( Gange, RW; Parrish, JA, 1984)
"Erythema was evaluated 3 and 5 d later, and an action spectrum for prolonged sensitization was determined."1.27An action spectrum for photoinduction of prolonged cutaneous photosensitivity by topical 8-MOP. ( Anderson, RR; Gange, RW; Gold, RL; Natoli, VD, 1988)
"The results of the first six months of treatment of psoriasis with photochemotherapy in the Skin and Cancer Foundation's clinic resulted in 30 out of 53 patients being completely clear of psoriasis lesions, 14 showing progressive improvement (and subsequently clearing), four failures, and five withdrawals."1.26Photochemotherapy in psoriasis: the first six months in Australia. ( King, R; O'Brien, H; Paver, K; Poyzer, K, 1979)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199039 (56.52)18.7374
1990's15 (21.74)18.2507
2000's11 (15.94)29.6817
2010's4 (5.80)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wainwright, LK1
Parisi, AV1
Downs, NJ1
Al-Ismail, D1
Edwards, C1
Anstey, AV1
Berroeta, L1
Attili, S1
Wong, A1
Man, I4
Dawe, RS6
Ferguson, J6
Ibbotson, SH7
Dinkova-Kostova, AT1
Weidlich, S1
Farr, PM5
Wolf, CR1
Smith, G2
Leigh, H1
Forbes, PD2
Lawson, C1
Kim, DY1
White, D1
Brown, LD1
Wehmeier, DR1
Liu, J1
Bouchard, GF1
Kwok, YK1
McKinlay, J1
IMBRIE, JD2
DANIELS, F1
BERGERON, L1
HOPKINS, CE1
FITZPATRICK, TB4
CAHN, MM1
LEVY, EJ1
SHAFFER, B1
HAKIM, RE1
GRIFFIN, AC1
KNOX, JM1
BERGERON, LL1
BUCK, HW1
MAGNUS, IA1
PORTER, AD1
Beattie, PE1
Wilkie, MJ1
Rodríguez-Granados, MT1
Carrascosa, JM1
Gárate, T1
Gómez-Díez, S1
Guimaraens-Juantorena, D1
Coupez, L1
Agache, PG1
Petigny, M1
Gange, RW4
Parrish, JA5
Meffert, H1
Andersen, KE1
Sönnichsen, N1
Abijev, GA1
Roshchupkin, DI1
Pliquett, F2
Ermolayev, AV1
Sarycheva, IK1
Evstigneeva, RP1
Morison, WL1
Bloch, KJ1
Krugler, JI1
Kaidbey, KH3
Witkowski, TA1
Kligman, AM3
Potapenko, AIa1
Abiev, GA1
Zagotto, G1
Gia, O2
Baccichetti, F1
Uriarte, E1
Palumbo, M2
Bech-Thomsen, N1
Wulf, HC1
Sakuntabhai, A2
Sharpe, GR1
Diffey, BL2
González, S1
Pathak, MA1
Kumar, JR3
Haberman, HF3
Ranadive, NS3
Schempp, CM1
Schöpf, E1
Simon, JC1
Conconi, MT1
Montesi, F1
Parnigotto, PP1
Calzavara-Pinton, P1
Yeo, UC1
Shin, JH1
Yang, JM1
Park, KB1
Kim, MM1
Bok, HS1
Lee, ES1
Dolezal, E1
Seeber, A1
Hönigsmann, H3
Tanew, A1
Azurdia, RM1
Dean, MP1
Rhodes, LE1
Schiener, R1
Behrens-Williams, SC1
Pillekamp, H1
Kaskel, P1
Peter, RU1
Kerscher, M1
Savin, RC1
Greaves, MW1
Hensby, CN1
Black, AK1
Plummer, NA1
Fincham, N1
Warin, AP1
Camp, R1
Rosten, M1
Wolff, K1
Gschnait, F1
Konrad, K1
Eaglstein, WH1
Sakai, M1
Mizuno, N2
Rosario, R1
Mark, GJ1
Mihm, MC1
Plewig, G1
Hofmann, C1
Braun-Falco, O1
Nath, G1
Kreitmair, A1
King, R1
Poyzer, K1
Paver, K1
O'Brien, H1
Melski, JW1
Tanenbaum, L1
Bleich, HL1
Davies, RE1
Urbach, F1
Schaefer, H1
Vivell, K1
Kentsch, V1
Schalla, W1
Jenny, S1
Menon, IA1
Jeanmougin, M1
Manciet, JR1
Castelneau, JP1
Smadja, J1
Dubertret, L1
Gasparro, FP1
Mclelland, J1
Fisher, C1
Cox, NH1
Ortel, B1
Imokawa, G1
Tejima, T1
Koulu, LM1
Jansén, CT1
Takashima, A1
Sunohara, A1
Gold, RL1
Anderson, RR1
Natoli, VD1
Kaidbey, K1
Stolk, LM1
Siddiqui, AH1
Westerhof, W1
Cormane, RH1
Giles, A1
Wamer, W1
Kornhauser, A1
Newmann, EA1
Parker, RD1
Bacchichetti, F1
Antonello, C1
Carlassare, F1
Bordin, F1
Douglas, WS1
Railton, R1
Newman, PN1
Valtonen, EJ1
Levine, GM1
Harber, LC1
Kahn, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Characterisation of the Time-course Response of UV-induced Erythema[NCT04290273]10 participants (Anticipated)Interventional2023-09-30Not yet recruiting
Adaption of the Skin Sun Sensitivity Scale for People With All Pigment Varieties[NCT01975038]292 participants (Actual)Observational2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for methoxsalen and Erythema

ArticleYear
[Systemic photoallergy induced by methoxalen].
    Annales de dermatologie et de venereologie, 1992, Volume: 119, Issue:4

    Topics: Adult; Erythema; Female; Humans; Male; Methoxsalen; Patch Tests; Photosensitivity Disorders; Psorias

1992
Psoralen photochemotherapy--mechanisms, drugs, toxicity.
    Current problems in dermatology, 1986, Volume: 15

    Topics: DNA; Erythema; Furocoumarins; Humans; Methoxsalen; Neoplasms, Radiation-Induced; Photosensitivity Di

1986

Trials

5 trials available for methoxsalen and Erythema

ArticleYear
Erythema action spectrum of topical 8-methoxypsoralen-sensitized skin re-evaluated: implications for routine clinical practice.
    The British journal of dermatology, 2016, Volume: 174, Issue:1

    Topics: Action Spectrum; Adult; Aged; Analysis of Variance; Dermatitis, Phototoxic; Dose-Response Relationsh

2016
The influence of infrared radiation on short-term ultraviolet-radiation-induced injuries.
    Archives of dermatology, 1982, Volume: 118, Issue:5

    Topics: Adult; Anthracenes; Erythema; Female; Humans; Infrared Rays; Male; Methoxsalen; Photosensitivity Dis

1982
Narrow band UVB (311 nm) phototherapy and PUVA photochemotherapy: a combination.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 1

    Topics: Administration, Cutaneous; Adult; Aged; Dermatitis, Phototoxic; Erythema; Humans; Male; Methoxsalen;

1998
Phototesting and dosimetry for photochemotherapy.
    The British journal of dermatology, 1977, Volume: 96, Issue:1

    Topics: Body Weight; Clinical Trials as Topic; Erythema; Humans; Methoxsalen; Psoriasis; Skin Pigmentation;

1977
Antipsoriatic, erythematogenic, and Langerhans cell marker depleting effect of bath-psoralens plus ultraviolet A treatment. Comparison of 8-methoxypsoralen and trimethylpsoralen photosensitization.
    Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:5 Pt 1

    Topics: Adenosine Triphosphatases; Adolescent; Adult; Dose-Response Relationship, Drug; Erythema; Female; HL

1988

Other Studies

62 other studies available for methoxsalen and Erythema

ArticleYear
Concurrent evaluation of personal damaging and beneficial UV exposures over an extended period.
    Journal of photochemistry and photobiology. B, Biology, 2017, Volume: 170

    Topics: Erythema; Film Dosimetry; Humans; Methoxsalen; Phenols; Polymers; Seasons; Ultraviolet Rays; Vitamin

2017
Time course for development of psoralen plus ultraviolet A erythema following oral administration of 5-methoxypsoralen.
    The British journal of dermatology, 2009, Volume: 160, Issue:3

    Topics: 5-Methoxypsoralen; Adult; Aged; Erythema; Female; Humans; Male; Methoxsalen; Middle Aged; Photochemo

2009
Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.
    The British journal of dermatology, 2012, Volume: 166, Issue:2

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Erythema; Female; Gene Expression; Genoty

2012
Miniature swine model of phototoxicity testing.
    Photodermatology, photoimmunology & photomedicine, 2012, Volume: 28, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation, P

2012
The time course of topical PUVA erythema following 15- and 5-minute methoxsalen immersion.
    Archives of dermatology, 2003, Volume: 139, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration

2003
An intraindividual comparative study of psoralen-UVA erythema induced by bath 8-methoxypsoralen and 4, 5', 8-trimethylpsoralen.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Erythema; Female; Humans; Male; Methoxsalen; Middle Aged; P

2003
An intraindividual study of the characteristics of erythema induced by bath and oral methoxsalen photochemotherapy and narrowband ultraviolet B.
    Photochemistry and photobiology, 2003, Volume: 78, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adult; Erythema; Female; Humans; Methoxsalen; Middle

2003
Increased erythema threshold six weeks after a single exposure to sunlight plus oral methoxsalen.
    The Journal of investigative dermatology, 1959, Volume: 32, Issue:2, Part 2

    Topics: Erythema; Furans; Humans; Methoxsalen; Sunburn; Sunlight

1959
Normal skin reactions to ultraviolet light. I. An attempt to modify normal erythema and pigmentation with methoxsalen.
    The Journal of investigative dermatology, 1961, Volume: 36

    Topics: Erythema; Humans; Methoxsalen; Pigmentation; Skin Physiological Phenomena; Sunlight; Ultraviolet Ray

1961
Erythema and tumor formation in methoxsalen-treated mice exposed to flourescent light.
    Archives of dermatology, 1960, Volume: 82

    Topics: Animals; Dermatitis, Phototoxic; Erythema; Humans; Light; Methoxsalen; Mice; Neoplasms; Photosensiti

1960
Further studies demonstrating an increased erythemal threshold following oral methoxsalen.
    The Journal of investigative dermatology, 1960, Volume: 35

    Topics: Erythema; Humans; Methoxsalen; Skin Physiological Phenomena; Sunlight

1960
The action spectrum of 8-methoxypsoralen for erythema in human skin. Preliminary studies with a monochromator.
    The British journal of dermatology, 1960, Volume: 72

    Topics: Erythema; Humans; Methoxsalen; Skin; Sunburn

1960
Can dietary furanocoumarin ingestion enhance the erythemal response during high-dose UVA1 therapy?
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1

    Topics: Adult; Aged; Apium; Diet; Erythema; Female; Food Handling; Furocoumarins; Hot Temperature; Humans; M

2007
[Consensus document on bath-PUVA therapy. The Spanish Photobiology Group of the Spanish Academy of Dermatology and Venereology].
    Actas dermo-sifiliograficas, 2007, Volume: 98, Issue:3

    Topics: Administration, Cutaneous; Baths; Dermatitis, Phototoxic; Dose-Response Relationship, Drug; Dose-Res

2007
Effect of UV-B erythema of psoralen, trimethylpsoralen, and 8 methoxypsoralen.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:5

    Topics: Adult; Dose-Response Relationship, Drug; Erythema; Female; Ficusin; Furocoumarins; Humans; Male; Met

1980
Cutaneous phototoxicity due to psoralens.
    National Cancer Institute monograph, 1984, Volume: 66

    Topics: Administration, Oral; Administration, Topical; Animals; DNA; Dose-Response Relationship, Drug; Eryth

1984
Phototoxicity and antipsoriatic effect of a topical methoxypsoralen solution in relation to the application time.
    Photo-dermatology, 1984, Volume: 1, Issue:4

    Topics: Administration, Topical; Adult; Erythema; Female; Humans; Male; Methoxsalen; Photochemotherapy; Phot

1984
PUVA-induced erythema and changes in mechanoelectrical properties of skin. Inhibition by tocopherols.
    Archives of dermatological research, 1984, Volume: 276, Issue:1

    Topics: Animals; Antioxidants; Erythema; Galvanic Skin Response; Humans; Methoxsalen; Photochemotherapy; PUV

1984
In vivo effects of PUVA on lymphocytes function.
    The British journal of dermatology, 1981, Volume: 104, Issue:4

    Topics: Adult; B-Lymphocytes; Dose-Response Relationship, Drug; Erythema; Humans; Leukocyte Count; Lymphocyt

1981
Cumulative effects from repeated exposures to ultraviolet radiation.
    The Journal of investigative dermatology, 1981, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Erythema

1981
[Alpha-tocopherol inhibition of erythema in skin photosensitized by 8-methoxypsoralen].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 89, Issue:5

    Topics: Animals; Erythema; Male; Methoxsalen; Photosensitivity Disorders; Rabbits; Skin; Ultraviolet Rays; V

1980
Synthesis and photobiological properties of 4-hydroxymethyl-4'-methylpsoralen derivatives.
    Photochemistry and photobiology, 1993, Volume: 58, Issue:4

    Topics: Animals; DNA; Dose-Response Relationship, Radiation; Erythema; Furocoumarins; Guinea Pigs; Methoxsal

1993
A polychromatic action spectrum for photosensitivity to orally administered 8-methoxypsoralen in humans.
    Clinical and experimental dermatology, 1994, Volume: 19, Issue:1

    Topics: Administration, Oral; Adult; Dermatitis, Phototoxic; Dose-Response Relationship, Radiation; Erythema

1994
Response of psoriasis to twice weekly PUVA.
    The British journal of dermatology, 1993, Volume: 128, Issue:2

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythema; H

1993
PUVA erythemal sensitivity depends on plasma psoralen concentration and UVA sensitivity.
    The British journal of dermatology, 1993, Volume: 128, Issue:5

    Topics: Adult; Aged; Dose-Response Relationship, Radiation; Erythema; Female; Humans; Male; Methoxsalen; Mid

1993
Inhibition of ultraviolet-induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by polypodium leucotomos.
    Photodermatology, photoimmunology & photomedicine, 1996, Volume: 12, Issue:2

    Topics: Animals; Antioxidants; Erythema; Guinea Pigs; Humans; In Vitro Techniques; Lipid Peroxidation; Metho

1996
Modulation of 8-methoxypsoralen-photoinduced cutaneous inflammatory reactions by various chemotherapeutic agents in vivo.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Acetophenones; Animals; Capillary Permeability; Erythema; Ibuprofen; Indoles; Indomethacin; Masoproc

1996
Phototesting in bath-PUVA: marked reduction of 8-methoxypsoralen (8-MOP) activity within one hour after an 8-MOP bath.
    Photodermatology, photoimmunology & photomedicine, 1996, Volume: 12, Issue:3

    Topics: Baths; Dose-Response Relationship, Drug; Erythema; Humans; Methoxsalen; Photosensitizing Agents; PUV

1996
Comparative studies on the tolerance to photoinduced cutaneous inflammatory reactions by psoralen and rose bengal.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3

    Topics: Animals; Capillary Permeability; Dermatitis, Phototoxic; Desensitization, Immunologic; Erythema; Fic

1997
Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:4

    Topics: 5-Methoxypsoralen; Animals; Antineoplastic Agents; Cell Division; Dermatitis, Phototoxic; Dose-Respo

1998
Psoralen-ultraviolet A-induced erythema: sensitivity correlates with the concentrations of psoralen in suction blister fluid.
    The British journal of dermatology, 2000, Volume: 142, Issue:4

    Topics: Adolescent; Adult; Blister; Erythema; Female; Humans; Male; Methoxsalen; Middle Aged; Predictive Val

2000
Correlation between bathing time and photosensitivity in 8-methoxypsoralen (8-MOP) bath PUVA.
    Photodermatology, photoimmunology & photomedicine, 2000, Volume: 16, Issue:4

    Topics: Adult; Baths; Erythema; Humans; Methoxsalen; PUVA Therapy; Statistics, Nonparametric; Time Factors

2000
Reduction in 8-methoxypsoralen immersion time alters the erythemal response to bath PUVA.
    Photodermatology, photoimmunology & photomedicine, 2000, Volume: 16, Issue:4

    Topics: Adult; Baths; Erythema; Female; Forearm; Humans; Linear Models; Male; Methoxsalen; PUVA Therapy; Sta

2000
The effect of methoxsalen dose on ultraviolet-A-induced erythema.
    The Journal of investigative dermatology, 2001, Volume: 116, Issue:5

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Erythema; Huma

2001
Can the immersion time of PUVA bath therapy be shortened?
    Acta dermato-venereologica, 2002, Volume: 82, Issue:1

    Topics: Baths; Dose-Response Relationship, Drug; Erythema; Female; Follow-Up Studies; Humans; Immersion; Mal

2002
Photochemotherapy for psoriasis--PUVA breaking through "the heartbreak".
    Connecticut medicine, 1978, Volume: 42, Issue:11

    Topics: Adult; Drug Eruptions; Erythema; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Psoriasis; Ult

1978
Inflammatory reactions induced by ultraviolet irradiation.
    Bulletin du cancer, 1978, Volume: 65, Issue:3

    Topics: Arachidonic Acids; Cell Differentiation; Cyclic AMP; Erythema; Humans; Indomethacin; Inflammation; M

1978
Photochemotherapy of psoriasis (PUVA).
    The New Zealand medical journal, 1979, Aug-08, Volume: 90, Issue:641

    Topics: Administration, Oral; Adolescent; Erythema; Female; Humans; Methoxsalen; Nausea; Photochemotherapy;

1979
Ultraviolet radiation-induced inflammation and leukocytes.
    The Journal of investigative dermatology, 1979, Volume: 72, Issue:2

    Topics: Animals; Cell Count; Cyclophosphamide; Erythema; Guinea Pigs; Inflammation; Leukocytes; Leukopenia;

1979
Histological changes produced in skin by equally erythemogenic doses of UV-A, UV-B, UV-C and UV-A with psoralens.
    The British journal of dermatology, 1979, Volume: 101, Issue:3

    Topics: Adult; Erythema; Female; Humans; Male; Methoxsalen; Photochemotherapy; Radiation Dosage; Skin; Ultra

1979
A new apparatus for the delivery of high intensity UVA and UVA+UVB irradiation, and some dermatological applications.
    The British journal of dermatology, 1978, Volume: 98, Issue:1

    Topics: Acrodermatitis; Adult; Aged; Erythema; Erythropoiesis; Female; Humans; Male; Methoxsalen; Photochemo

1978
Photochemotherapy in psoriasis: the first six months in Australia.
    The Medical journal of Australia, 1979, Jan-13, Volume: 1, Issue:1

    Topics: Australia; Darier Disease; Dermatitis; Edema; Erythema; Humans; Methoxsalen; Photochemotherapy; Prur

1979
Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial.
    The Journal of investigative dermatology, 1977, Volume: 68, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Erythema; Female; Humans; Ma

1977
Phototoxicity and photocarcinogenesis: comparative effects of anthracene and 8-methoxypsoralen in the skin of mice.
    Food and cosmetics toxicology, 1976, Volume: 14, Issue:4

    Topics: Animals; Anthracenes; Erythema; Methoxsalen; Mice; Neoplasms; Neoplasms, Experimental; Neoplasms, Ra

1976
Further studies of photoaugmentation in humans: phototoxic reactions.
    The Journal of investigative dermatology, 1975, Volume: 65, Issue:5

    Topics: Adult; Coal Tar; Erythema; Humans; Male; Methoxsalen; Photosensitivity Disorders; Sunburn; Ultraviol

1975
Simplification of local therapy of psoriasis with 8-methoxypsoralen. Methods and initial results.
    The British journal of dermatology, 1976, Volume: 94, Issue:4

    Topics: Erythema; Evaluation Studies as Topic; Female; Humans; Male; Methoxsalen; Oils; Ointment Bases; Pigm

1976
Photoinduced cutaneous inflammatory response by psoralens.
    Journal of photochemistry and photobiology. B, Biology, 1992, Jun-30, Volume: 14, Issue:1-2

    Topics: Administration, Topical; Animals; Darkness; Dose-Response Relationship, Drug; Erythema; Inflammation

1992
An action spectrum for the elicitation of erythema in skin persistently sensitized by photobound 8-methoxypsoralen.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:5

    Topics: Erythema; Humans; Methoxsalen

1991
The relationship between plasma psoralen concentration and psoralen-UVA erythema.
    The British journal of dermatology, 1991, Volume: 124, Issue:6

    Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiat

1991
An action spectrum for the elicitation of erythema in skin persistently sensitized by photobound 8-methoxypsoralen.
    The Journal of investigative dermatology, 1990, Volume: 94, Issue:6

    Topics: Differential Threshold; Dose-Response Relationship, Radiation; Erythema; Humans; Light; Methoxsalen;

1990
A possible role of prostaglandins in PUVA-induced inflammation: implication by organ cultured skin.
    The Journal of investigative dermatology, 1989, Volume: 92, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dermatitis; Erythema; Guinea Pigs; Methoxsalen; Organ

1989
Comparison of the relative therapeutic efficacy of 7-methyl pyridopsoralen and 8-methoxypsoralen in photochemotherapy in psoriasis treatment.
    The Journal of dermatology, 1988, Volume: 15, Issue:3

    Topics: Adult; Aged; Erythema; Female; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Photochemother

1988
An action spectrum for photoinduction of prolonged cutaneous photosensitivity by topical 8-MOP.
    The Journal of investigative dermatology, 1988, Volume: 90, Issue:6

    Topics: Cross-Linking Reagents; DNA Damage; Dose-Response Relationship, Drug; Erythema; Humans; Methoxsalen;

1988
Comparison of methods for assessing photoprotection against ultraviolet A in vivo.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:2 Pt 1

    Topics: Adolescent; Adult; Anthracenes; Benzoates; Benzophenones; Chalcones; Erythema; Female; Humans; Male;

1987
Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen.
    The British journal of dermatology, 1985, Volume: 112, Issue:4

    Topics: 5-Methoxypsoralen; Administration, Oral; Adult; Aged; Biological Availability; Capsules; Erythema; F

1985
In vivo protective effect of beta-carotene against psoralen phototoxicity.
    Photochemistry and photobiology, 1985, Volume: 41, Issue:6

    Topics: Animals; beta Carotene; Carotenoids; Erythema; Female; Methoxsalen; Rats; Rats, Inbred Strains; Skin

1985
A device for irradiating guinea-pig skin with ultraviolet light.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1985, Volume: 23, Issue:7

    Topics: Animals; Erythema; Guinea Pigs; Methoxsalen; Ultraviolet Rays

1985
Photobiological properties of some water-soluble 5-MOP and 8-MOP derivatives.
    Photo-dermatology, 1985, Volume: 2, Issue:4

    Topics: 5-Methoxypsoralen; Animals; Carcinoma, Ehrlich Tumor; Cell Division; DNA; Erythema; Guinea Pigs; Met

1985
Sunscreens and PUVA.
    Photo-dermatology, 1985, Volume: 2, Issue:4

    Topics: Erythema; Humans; Methoxsalen; PUVA Therapy; Skin Neoplasms; Spectrophotometry, Ultraviolet; Sunscre

1985
Studies of the mechanism of ultra-violet erythema formation. 3. A method for biological testing of ultra-violet radiation sources and substances affecting the degree of erythema.
    Acta dermato-venereologica, 1966, Volume: 46, Issue:4

    Topics: Aminopyrine; Animals; Erythema; Methoxsalen; Mice; Phenylbutazone; Skin; Ultraviolet Rays

1966
The effect of humidity on the phototoxic response to 8-methoxypsoralen in guinea pigs.
    Acta dermato-venereologica, 1969, Volume: 49, Issue:1

    Topics: Animals; Erythema; Guinea Pigs; Humidity; Methoxsalen; Photosensitivity Disorders; Skin Absorption

1969
Intensified contact sensitization to benzyl salicylate. Phototoxic effects of topical psoralen therapy.
    Archives of dermatology, 1971, Volume: 103, Issue:5

    Topics: Adolescent; Adult; Child; Dermatitis, Contact; Erythema; Female; Humans; Hypersensitivity, Delayed;

1971