methoxsalen has been researched along with Disease, Pulmonary in 2 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with the cytochrome P-450 inhibitor cimetidine or 8-methoxypsoralen did not improve survival or reduce lung edema in rats exposed to 100% oxygen." | 3.68 | Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats. ( Hunt, CM; Kennedy, TP; Piantadosi, CA; Todd, NW; Whorton, AR, 1992) |
| "One patient with generalized morphea had stopped EP after 3 months because of loss of vascular access and could not be evaluated." | 2.68 | Extracorporeal photochemotherapy in systemic sclerosis and severe morphea. ( Cribier, B; Faradji, T; Grosshans, E; Le Coz, C; Oberling, F, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cribier, B | 1 |
| Faradji, T | 1 |
| Le Coz, C | 1 |
| Oberling, F | 1 |
| Grosshans, E | 1 |
| Todd, NW | 1 |
| Hunt, CM | 1 |
| Kennedy, TP | 1 |
| Piantadosi, CA | 1 |
| Whorton, AR | 1 |
1 trial available for methoxsalen and Disease, Pulmonary
| Article | Year |
|---|---|
Extracorporeal photochemotherapy in systemic sclerosis and severe morphea.
Topics: Adolescent; Adult; Aged; Arthritis; Disease Progression; Drug Tolerance; Esophageal Diseases; Female | 1995 |
1 other study available for methoxsalen and Disease, Pulmonary
| Article | Year |
|---|---|
Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cimetidine; Cytochrome P-450 CYP1A1; | 1992 |