Page last updated: 2024-10-31

methoxsalen and Digitate Dermatosis

methoxsalen has been researched along with Digitate Dermatosis in 4 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Research Excerpts

ExcerptRelevanceReference
" In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml."1.26Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982)
"Plasma and skin blister fluid levels of 8-MOP are determined 2 h following oral administration of 40-60 mg 8-MOP."1.26Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method. ( Korting, HC; Mutschler, E; Roser-Maass, E; Schäfer-Korting, M, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schäfer-Korting, M2
Korting, HC2
Roser-Maass, E1
Mutschler, E1
Vella Briffa, D1
Warin, AP1
Calnan, CD1
Laksmipathi, T1
Gould, P1
Johnson, BE1
Mackenzie, LA1
Frain-Bell, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355]Phase 110 participants Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for methoxsalen and Digitate Dermatosis

ArticleYear
Intraindividual variations of 8-methoxypsoralen plasma levels.
    Archives of dermatological research, 1982, Volume: 272, Issue:1-2

    Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic

1982
Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.
    Archives of dermatological research, 1982, Volume: 272, Issue:1-2

    Topics: Adult; Aged; Blister; Densitometry; Exudates and Transudates; Female; Fluorometry; Humans; Male; Met

1982
Parakeratosis variegata: a report of two cases and their treatment with PUVA.
    Clinical and experimental dermatology, 1979, Volume: 4, Issue:4

    Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Parapsoriasis; Photochemoth

1979
Proceedings: Photochemotherapy. A study of its efficacy in fifty patients suffering from psoriasis and other dermatoses.
    The British journal of dermatology, 1976, Volume: 95 Suppl 14

    Topics: Humans; Methoxsalen; Mycosis Fungoides; Parapsoriasis; Psoriasis; Skin Neoplasms; Ultraviolet Therap

1976