methoxsalen has been researched along with Digitate Dermatosis in 4 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml." | 1.26 | Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982) |
| "Plasma and skin blister fluid levels of 8-MOP are determined 2 h following oral administration of 40-60 mg 8-MOP." | 1.26 | Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method. ( Korting, HC; Mutschler, E; Roser-Maass, E; Schäfer-Korting, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schäfer-Korting, M | 2 |
| Korting, HC | 2 |
| Roser-Maass, E | 1 |
| Mutschler, E | 1 |
| Vella Briffa, D | 1 |
| Warin, AP | 1 |
| Calnan, CD | 1 |
| Laksmipathi, T | 1 |
| Gould, P | 1 |
| Johnson, BE | 1 |
| Mackenzie, LA | 1 |
| Frain-Bell, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355] | Phase 1 | 10 participants | Interventional | 2003-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for methoxsalen and Digitate Dermatosis
| Article | Year |
|---|---|
Intraindividual variations of 8-methoxypsoralen plasma levels.
Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic | 1982 |
Determination of 8-methoxypsoralen levels in plasma and skin suction blister fluid by a new sensitive fluorodensitometric method.
Topics: Adult; Aged; Blister; Densitometry; Exudates and Transudates; Female; Fluorometry; Humans; Male; Met | 1982 |
Parakeratosis variegata: a report of two cases and their treatment with PUVA.
Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Parapsoriasis; Photochemoth | 1979 |
Proceedings: Photochemotherapy. A study of its efficacy in fifty patients suffering from psoriasis and other dermatoses.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Parapsoriasis; Psoriasis; Skin Neoplasms; Ultraviolet Therap | 1976 |