methoxsalen has been researched along with Dermatitis, Contact in 29 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin." | 7.66 | Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978) |
| "Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin." | 3.66 | Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978) |
| "It concerns the Wistar-derived rat with contact hypersensitivity (CHS), also a T cell mediated disorder that has already been studied extensively in several other fields of research." | 1.28 | An animal model for extracorporeal photochemotherapy based on contact hypersensitivity. ( Beijersbergen van Henegouwen, GM; van Iperen, HP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (75.86) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BRIER, RL | 1 |
| Epstein, JH | 1 |
| Lynch, DH | 1 |
| Gurish, MF | 1 |
| Daynes, RA | 1 |
| Morison, WL | 1 |
| Kripke, ML | 1 |
| Pathak, MA | 1 |
| Horio, T | 2 |
| Okamoto, H | 3 |
| Meffert, H | 1 |
| Wischnewsky, G | 1 |
| Günther, W | 1 |
| Lübke, M | 1 |
| Austad, J | 1 |
| Mørk, NJ | 1 |
| Weissmann, I | 1 |
| Wagner, G | 1 |
| Plewig, G | 1 |
| Thorvaldsen, J | 1 |
| Volden, G | 1 |
| Bech-Thomsen, N | 1 |
| Wulf, HC | 1 |
| van Iperen, HP | 3 |
| Beijersbergen van Henegouwen, GM | 2 |
| Beijersbergen van Henegouwen, MJ | 1 |
| Sauter, C | 1 |
| de Koning, GA | 1 |
| Notowicz, A | 1 |
| Stolz, E | 1 |
| Saihan, EM | 1 |
| Hannuksela, M | 1 |
| Karvonen, J | 1 |
| Möller, H | 2 |
| Ljunggren, B | 1 |
| Sams, WM | 1 |
| Guo, Z | 1 |
| Danno, K | 1 |
| Imamura, S | 1 |
| Takashima, A | 1 |
| Yamamoto, K | 1 |
| Kimura, S | 2 |
| Takakuwa, Y | 1 |
| Mizuno, N | 2 |
| Sjövall, P | 1 |
| Christensen, OB | 1 |
| Imokawa, G | 1 |
| Kawai, M | 1 |
| Mishima, Y | 1 |
| Motegi, I | 1 |
| Sugano, H | 1 |
| Ikoma, M | 1 |
| Suzuki, K | 1 |
| Musajo, L | 1 |
| Rodighiero, G | 1 |
| Kahn, G | 1 |
4 reviews available for methoxsalen and Dermatitis, Contact
| Article | Year |
|---|---|
Phototoxicity and photoallergy in man.
Topics: Acute Disease; Allergens; Anti-Infective Agents; Antigen-Antibody Complex; Chronic Disease; Dermatit | 1983 |
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; beta Carotene; Carotenoids; Chloro | 1982 |
The Immunology of photocontact dermatitis.
Topics: Anilides; Animals; Antigens; Carrier Proteins; Cell Migration Inhibition; Dermatitis, Contact; Hapte | 1975 |
Mode of photosensitizing action of furocoumarins.
Topics: Animals; Bacteria; Cell Transformation, Neoplastic; Cells; Coumarins; Dermatitis, Contact; DNA; Fura | 1972 |
25 other studies available for methoxsalen and Dermatitis, Contact
| Article | Year |
|---|---|
Polymorphous light eruption and solar keratosis treatment with 8-methoxypsoralen.
Topics: Dermatitis, Contact; Humans; Keratosis; Keratosis, Actinic; Methoxsalen; Sunlight | 1959 |
Relationship between epidermal Langerhans cell density ATPase activity and the induction of contact hypersensitivity.
Topics: 4-Aminobenzoic Acid; Adenosine Triphosphatases; Adrenal Cortex Hormones; Animals; Dermatitis, Contac | 1981 |
Systemic suppression of contact hypersensitivity by ultraviolet b radiation or methoxsalen/ultraviolet a radiation in the guinea pig.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Female; Guinea Pigs; Immune Tolerance; Methoxsal | 1984 |
Immunologic unresponsiveness induced by topical application of hapten to PUVA-treated skin in guinea pigs.
Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Haptens; Methoxsalen; PUVA | 1983 |
[Darkness effect in photochemotherapy. I. Effect of 8-methoxypsoralen on the epidermal patch test in allergic contact eczema].
Topics: Adult; Aged; Dermatitis, Atopic; Dermatitis, Contact; Drug Evaluation, Preclinical; Flumethasone; Hu | 1983 |
The mechanisms of inhibitory effect of 8-methoxypsoralen and long-wave ultraviolet light on experimental contact sensitization.
Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Langerhans Cells; Methoxsal | 1982 |
Effects of PUVA on delayed hypersensitivity in the guinea-pig.
Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Methoxsalen; Photochemother | 1981 |
Contact allergy to 8-methyxypsoralen.
Topics: Adult; Alopecia Areata; Dermatitis, Contact; Humans; Male; Methoxsalen; Photochemotherapy | 1980 |
PUVA-induced diminution of contact allergic and irritant skin reactions.
Topics: Adult; Dermatitis, Atopic; Dermatitis, Contact; Female; Humans; Male; Methoxsalen; Middle Aged; Phot | 1980 |
8-Methoxypsoralen urticaria.
Topics: Dermatitis, Contact; Diagnosis, Differential; Female; Humans; Methoxsalen; Middle Aged; Urticaria | 1994 |
An animal model and new photosensitizers for photopheresis.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Male; Methoxsalen; Photo | 1993 |
Chlorpromazine, a candidate drug for photopheresis.
Topics: Adoptive Transfer; Animals; Cells, Cultured; Chlorpromazine; Dermatitis, Contact; Dinitrofluorobenze | 1996 |
[Heracl'eum mantegazzi'anum: photosensitization].
Topics: 5-Methoxypsoralen; Breast Neoplasms; Dermatitis, Contact; Diagnosis, Differential; Female; Humans; M | 2001 |
[Phototoxic reactions to 8-methoxypsoralen as occupational dermatosis].
Topics: Dermatitis, Contact; Dermatitis, Occupational; Humans; Male; Methoxsalen; Middle Aged; Occupations; | 1979 |
Contact allergy to methoxsalen.
Topics: Dermatitis, Contact; Drug Eruptions; Female; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Ps | 1979 |
Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Baths; Blister; Dermatitis, Contact; Female; Furocoumarins; Humans; Male; M | 1978 |
Phototoxicity of Dictamnus alba.
Topics: Dermatitis, Contact; Humans; Magnoliopsida; Methoxsalen; Middle Aged; Photosensitivity Disorders | 1978 |
Psoralen photoallergy caused by plant contact.
Topics: Coumarins; Dermatitis, Contact; Ficusin; Humans; Male; Methoxsalen; Middle Aged; Photosensitivity Di | 1977 |
An animal model for extracorporeal photochemotherapy based on contact hypersensitivity.
Topics: Acetone; Allergens; Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Immu | 1992 |
The effects of non-interval PUVA treatment on Langerhans cells and contact hypersensitivity.
Topics: Animals; Dermatitis, Contact; Female; Guinea Pigs; Langerhans Cells; Methoxsalen; Mice; Mice, Inbred | 1992 |
Allergic contact and photocontact dermatitis due to psoralens in patients with psoriasis treated with topical PUVA.
Topics: Adult; Dermatitis, Contact; Female; Furocoumarins; Humans; Incidence; Male; Methoxsalen; Middle Aged | 1991 |
Single exposure to ultraviolet irradiation and elicitation of human allergic contact dermatitis.
Topics: Adolescent; Adult; Dermatitis, Contact; Female; Humans; Langerhans Cells; Methoxsalen; Middle Aged; | 1985 |
Differential analysis of experimental hypermelanosis induced by UVB, PUVA, and allergic contact dermatitis using a brownish guinea pig model.
Topics: Animals; Dermatitis, Contact; Guinea Pigs; Melanocytes; Methoxsalen; Microscopy, Electron; Pigmentat | 1986 |
[Theory and practice of the photo patch test].
Topics: Adult; Aged; Dermatitis, Contact; Female; Fluorescent Dyes; Humans; Hydrocarbons, Halogenated; Light | 1972 |
Intensified contact sensitization to benzyl salicylate. Phototoxic effects of topical psoralen therapy.
Topics: Adolescent; Adult; Child; Dermatitis, Contact; Erythema; Female; Humans; Hypersensitivity, Delayed; | 1971 |