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methoxsalen and Dermatitis, Contact

methoxsalen has been researched along with Dermatitis, Contact in 29 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.

Research Excerpts

ExcerptRelevanceReference
"Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin."7.66Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978)
"Seventy-four patients with psoriasis were treated using a trioxsalen bath (50 mg/150 l of water) and long wave ultraviolet light (UVA) given in an ordinary PUVA-cabin."3.66Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis. ( Hannuksela, M; Karvonen, J, 1978)
"It concerns the Wistar-derived rat with contact hypersensitivity (CHS), also a T cell mediated disorder that has already been studied extensively in several other fields of research."1.28An animal model for extracorporeal photochemotherapy based on contact hypersensitivity. ( Beijersbergen van Henegouwen, GM; van Iperen, HP, 1992)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199022 (75.86)18.7374
1990's6 (20.69)18.2507
2000's1 (3.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRIER, RL1
Epstein, JH1
Lynch, DH1
Gurish, MF1
Daynes, RA1
Morison, WL1
Kripke, ML1
Pathak, MA1
Horio, T2
Okamoto, H3
Meffert, H1
Wischnewsky, G1
Günther, W1
Lübke, M1
Austad, J1
Mørk, NJ1
Weissmann, I1
Wagner, G1
Plewig, G1
Thorvaldsen, J1
Volden, G1
Bech-Thomsen, N1
Wulf, HC1
van Iperen, HP3
Beijersbergen van Henegouwen, GM2
Beijersbergen van Henegouwen, MJ1
Sauter, C1
de Koning, GA1
Notowicz, A1
Stolz, E1
Saihan, EM1
Hannuksela, M1
Karvonen, J1
Möller, H2
Ljunggren, B1
Sams, WM1
Guo, Z1
Danno, K1
Imamura, S1
Takashima, A1
Yamamoto, K1
Kimura, S2
Takakuwa, Y1
Mizuno, N2
Sjövall, P1
Christensen, OB1
Imokawa, G1
Kawai, M1
Mishima, Y1
Motegi, I1
Sugano, H1
Ikoma, M1
Suzuki, K1
Musajo, L1
Rodighiero, G1
Kahn, G1

Reviews

4 reviews available for methoxsalen and Dermatitis, Contact

ArticleYear
Phototoxicity and photoallergy in man.
    Journal of the American Academy of Dermatology, 1983, Volume: 8, Issue:2

    Topics: Acute Disease; Allergens; Anti-Infective Agents; Antigen-Antibody Complex; Chronic Disease; Dermatit

1983
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
    Journal of the American Academy of Dermatology, 1982, Volume: 7, Issue:3

    Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; beta Carotene; Carotenoids; Chloro

1982
The Immunology of photocontact dermatitis.
    International journal of dermatology, 1975, Volume: 14, Issue:4

    Topics: Anilides; Animals; Antigens; Carrier Proteins; Cell Migration Inhibition; Dermatitis, Contact; Hapte

1975
Mode of photosensitizing action of furocoumarins.
    Photophysiology, 1972, Issue:7

    Topics: Animals; Bacteria; Cell Transformation, Neoplastic; Cells; Coumarins; Dermatitis, Contact; DNA; Fura

1972

Other Studies

25 other studies available for methoxsalen and Dermatitis, Contact

ArticleYear
Polymorphous light eruption and solar keratosis treatment with 8-methoxypsoralen.
    Journal of the Medical Association of the State of Alabama, 1959, Volume: 29

    Topics: Dermatitis, Contact; Humans; Keratosis; Keratosis, Actinic; Methoxsalen; Sunlight

1959
Relationship between epidermal Langerhans cell density ATPase activity and the induction of contact hypersensitivity.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 126, Issue:5

    Topics: 4-Aminobenzoic Acid; Adenosine Triphosphatases; Adrenal Cortex Hormones; Animals; Dermatitis, Contac

1981
Systemic suppression of contact hypersensitivity by ultraviolet b radiation or methoxsalen/ultraviolet a radiation in the guinea pig.
    Cellular immunology, 1984, Apr-15, Volume: 85, Issue:1

    Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Female; Guinea Pigs; Immune Tolerance; Methoxsal

1984
Immunologic unresponsiveness induced by topical application of hapten to PUVA-treated skin in guinea pigs.
    The Journal of investigative dermatology, 1983, Volume: 80, Issue:2

    Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Haptens; Methoxsalen; PUVA

1983
[Darkness effect in photochemotherapy. I. Effect of 8-methoxypsoralen on the epidermal patch test in allergic contact eczema].
    Dermatologische Monatschrift, 1983, Volume: 169, Issue:1

    Topics: Adult; Aged; Dermatitis, Atopic; Dermatitis, Contact; Drug Evaluation, Preclinical; Flumethasone; Hu

1983
The mechanisms of inhibitory effect of 8-methoxypsoralen and long-wave ultraviolet light on experimental contact sensitization.
    The Journal of investigative dermatology, 1982, Volume: 78, Issue:5

    Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Langerhans Cells; Methoxsal

1982
Effects of PUVA on delayed hypersensitivity in the guinea-pig.
    The British journal of dermatology, 1981, Volume: 105, Issue:6

    Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Female; Guinea Pigs; Methoxsalen; Photochemother

1981
Contact allergy to 8-methyxypsoralen.
    The British journal of dermatology, 1980, Volume: 102, Issue:1

    Topics: Adult; Alopecia Areata; Dermatitis, Contact; Humans; Male; Methoxsalen; Photochemotherapy

1980
PUVA-induced diminution of contact allergic and irritant skin reactions.
    Clinical and experimental dermatology, 1980, Volume: 5, Issue:1

    Topics: Adult; Dermatitis, Atopic; Dermatitis, Contact; Female; Humans; Male; Methoxsalen; Middle Aged; Phot

1980
8-Methoxypsoralen urticaria.
    Journal of the American Academy of Dermatology, 1994, Volume: 31, Issue:6

    Topics: Dermatitis, Contact; Diagnosis, Differential; Female; Humans; Methoxsalen; Middle Aged; Urticaria

1994
An animal model and new photosensitizers for photopheresis.
    Photochemistry and photobiology, 1993, Volume: 58, Issue:4

    Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Male; Methoxsalen; Photo

1993
Chlorpromazine, a candidate drug for photopheresis.
    Journal of photochemistry and photobiology. B, Biology, 1996, Volume: 34, Issue:2-3

    Topics: Adoptive Transfer; Animals; Cells, Cultured; Chlorpromazine; Dermatitis, Contact; Dinitrofluorobenze

1996
[Heracl'eum mantegazzi'anum: photosensitization].
    Praxis, 2001, Jan-18, Volume: 90, Issue:3

    Topics: 5-Methoxypsoralen; Breast Neoplasms; Dermatitis, Contact; Diagnosis, Differential; Female; Humans; M

2001
[Phototoxic reactions to 8-methoxypsoralen as occupational dermatosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1979, Volume: 30, Issue:1

    Topics: Dermatitis, Contact; Dermatitis, Occupational; Humans; Male; Methoxsalen; Middle Aged; Occupations;

1979
Contact allergy to methoxsalen.
    British medical journal, 1979, Jul-07, Volume: 2, Issue:6181

    Topics: Dermatitis, Contact; Drug Eruptions; Female; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Ps

1979
Trioxsalen bath plus UVA effective and safe in the treatment of psoriasis.
    The British journal of dermatology, 1978, Volume: 99, Issue:6

    Topics: Adolescent; Adult; Aged; Baths; Blister; Dermatitis, Contact; Female; Furocoumarins; Humans; Male; M

1978
Phototoxicity of Dictamnus alba.
    Contact dermatitis, 1978, Volume: 4, Issue:5

    Topics: Dermatitis, Contact; Humans; Magnoliopsida; Methoxsalen; Middle Aged; Photosensitivity Disorders

1978
Psoralen photoallergy caused by plant contact.
    Contact dermatitis, 1977, Volume: 3, Issue:2

    Topics: Coumarins; Dermatitis, Contact; Ficusin; Humans; Male; Methoxsalen; Middle Aged; Photosensitivity Di

1977
An animal model for extracorporeal photochemotherapy based on contact hypersensitivity.
    Journal of photochemistry and photobiology. B, Biology, 1992, Sep-15, Volume: 15, Issue:4

    Topics: Acetone; Allergens; Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Immu

1992
The effects of non-interval PUVA treatment on Langerhans cells and contact hypersensitivity.
    Journal of dermatological science, 1992, Volume: 3, Issue:2

    Topics: Animals; Dermatitis, Contact; Female; Guinea Pigs; Langerhans Cells; Methoxsalen; Mice; Mice, Inbred

1992
Allergic contact and photocontact dermatitis due to psoralens in patients with psoriasis treated with topical PUVA.
    The British journal of dermatology, 1991, Volume: 124, Issue:1

    Topics: Adult; Dermatitis, Contact; Female; Furocoumarins; Humans; Incidence; Male; Methoxsalen; Middle Aged

1991
Single exposure to ultraviolet irradiation and elicitation of human allergic contact dermatitis.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Dermatitis, Contact; Female; Humans; Langerhans Cells; Methoxsalen; Middle Aged;

1985
Differential analysis of experimental hypermelanosis induced by UVB, PUVA, and allergic contact dermatitis using a brownish guinea pig model.
    Archives of dermatological research, 1986, Volume: 278, Issue:5

    Topics: Animals; Dermatitis, Contact; Guinea Pigs; Melanocytes; Methoxsalen; Microscopy, Electron; Pigmentat

1986
[Theory and practice of the photo patch test].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1972, Volume: 82, Issue:9

    Topics: Adult; Aged; Dermatitis, Contact; Female; Fluorescent Dyes; Humans; Hydrocarbons, Halogenated; Light

1972
Intensified contact sensitization to benzyl salicylate. Phototoxic effects of topical psoralen therapy.
    Archives of dermatology, 1971, Volume: 103, Issue:5

    Topics: Adolescent; Adult; Child; Dermatitis, Contact; Erythema; Female; Humans; Hypersensitivity, Delayed;

1971