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methoxsalen and Dermatitis, Atopic

methoxsalen has been researched along with Dermatitis, Atopic in 11 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Research Excerpts

ExcerptRelevanceReference
"11 patients with atopic eczema have been treated using oral photochemotherapy."1.26[Oral photochemotherapy in atopic eczema]. ( Ortonne, JP; Sannwald, C; Thivolet, J, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Chu, Z1
Xu, Q1
Zhu, Q1
Ma, X1
Mo, J1
Lin, G1
Zhao, Y1
Gu, Y1
Bian, L1
Shao, L1
Guo, J1
Ye, W1
Li, J1
He, G1
Xu, Y1
Fang, YP1
Yang, SH1
Lee, CH1
Aljuffali, IA1
Kao, HC1
Fang, JY1
Tzaneva, S1
Kittler, H1
Holzer, G1
Reljic, D1
Weber, M1
Hönigsmann, H2
Tanew, A2
Miyauchi-Hashimoto, H1
Okamoto, H1
Sugihara, A1
Horio, T1
Sand, M1
Bechara, FG1
Sand, D1
Radenhausen, M1
Tomi, NS1
Altmeyer, P1
Hoffmann, K1
Meffert, H1
Wischnewsky, G1
Günther, W1
Lübke, M1
Thorvaldsen, J1
Volden, G1
Yoshiike, T1
Aikawa, Y1
Sindhvananda, J1
Ogawa, H1
Der-Petrossian, M1
Seeber, A1
Sannwald, C1
Ortonne, JP1
Thivolet, J1

Trials

3 trials available for methoxsalen and Dermatitis, Atopic

ArticleYear
5-Methoxypsoralen plus ultraviolet (UV) A is superior to medium-dose UVA1 in the treatment of severe atopic dermatitis: a randomized crossover trial.
    The British journal of dermatology, 2010, Volume: 162, Issue:3

    Topics: 5-Methoxypsoralen; Adolescent; Adult; Cross-Over Studies; Dermatitis, Atopic; Female; Humans; Male;

2010
Extracorporeal photopheresis as a treatment for patients with severe, refractory atopic dermatitis.
    Dermatology (Basel, Switzerland), 2007, Volume: 215, Issue:2

    Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Male; Methoxsalen; Middle Aged; Photopheresis;

2007
Half-side comparison study on the efficacy of 8-methoxypsoralen bath-PUVA versus narrow-band ultraviolet B phototherapy in patients with severe chronic atopic dermatitis.
    The British journal of dermatology, 2000, Volume: 142, Issue:1

    Topics: Adult; Chronic Disease; Dermatitis, Atopic; Humans; Methoxsalen; PUVA Therapy; Treatment Outcome; Ul

2000

Other Studies

8 other studies available for methoxsalen and Dermatitis, Atopic

ArticleYear
Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Animals; Boron Compounds; Calcitriol; Cyclic Nucleotide Phosphodiesterases, Type 4; Dermatitis, Atop

2021
What is the discrepancy between drug permeation into/across intact and diseased skins? Atopic dermatitis as a model.
    International journal of pharmaceutics, 2016, Jan-30, Volume: 497, Issue:1-2

    Topics: Animals; Cytokines; Dermatitis, Atopic; Dextrans; Filaggrin Proteins; Methotrexate; Methoxsalen; Mic

2016
Therapeutic and prophylactic effects of PUVA photochemotherapy on atopic dermatitis-like lesions in NC/Nga mice.
    Photodermatology, photoimmunology & photomedicine, 2005, Volume: 21, Issue:3

    Topics: Animals; Dermatitis, Atopic; Disease Models, Animal; Injections, Intraperitoneal; Male; Methoxsalen;

2005
[Darkness effect in photochemotherapy. I. Effect of 8-methoxypsoralen on the epidermal patch test in allergic contact eczema].
    Dermatologische Monatschrift, 1983, Volume: 169, Issue:1

    Topics: Adult; Aged; Dermatitis, Atopic; Dermatitis, Contact; Drug Evaluation, Preclinical; Flumethasone; Hu

1983
PUVA-induced diminution of contact allergic and irritant skin reactions.
    Clinical and experimental dermatology, 1980, Volume: 5, Issue:1

    Topics: Adult; Dermatitis, Atopic; Dermatitis, Contact; Female; Humans; Male; Methoxsalen; Middle Aged; Phot

1980
British Photodermatology Group guidelines for PUVA.
    The British journal of dermatology, 1994, Volume: 130, Issue:2

    Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis;

1994
A proposed guideline for psoralen photochemotherapy (PUVA) with atopic dermatitis: successful therapeutic effect on severe and intractable cases.
    Journal of dermatological science, 1993, Volume: 5, Issue:1

    Topics: Dermatitis, Atopic; Humans; Methoxsalen; Practice Guidelines as Topic; PUVA Therapy; Treatment Outco

1993
[Oral photochemotherapy in atopic eczema].
    Dermatologica, 1979, Volume: 159, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Dermatitis, Atopic; Female; Humans; Male; Methoxsalen; Phot

1979