methoxsalen has been researched along with Delayed Hypersensitivity in 8 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combination of methoxsalen and long-wave UV radiation (UV-A) is being used on a large scale in clinical practice to treat a variety of dermatoses, particularly psoriasis." | 4.76 | Mutagenicity and carcinogenicity of methoxsalen plus UV-A. ( Roelandts, R, 1984) |
| " Following the dosage parameters toxic side effects were rare and reversible." | 2.36 | [Oral photochemotherapy (author's transl)]. ( Gschnait, F, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roelandts, R | 1 |
| Moberg, S | 1 |
| Mobacken, H | 1 |
| Gschnait, F | 1 |
| Perez, MI | 2 |
| Yamane, Y | 2 |
| John, L | 2 |
| Gasparro, FP | 1 |
| Edelson, RL | 2 |
| Berger, CL | 1 |
| Laroche, L | 1 |
| Buehler, EV | 1 |
| Newmann, EA | 1 |
| Parker, RD | 1 |
| Epstein, JH | 1 |
| Kahn, G | 1 |
3 reviews available for methoxsalen and Delayed Hypersensitivity
| Article | Year |
|---|---|
Mutagenicity and carcinogenicity of methoxsalen plus UV-A.
Topics: Animals; Carcinogens; Guinea Pigs; Humans; Hypersensitivity, Delayed; Immunosuppression Therapy; In | 1984 |
[Oral photochemotherapy (author's transl)].
Topics: Adult; Dose-Response Relationship, Radiation; Eczema; Eye Protective Devices; Female; Humans; Hypers | 1977 |
Photoallergy. A review.
Topics: Anilides; Antibodies; Antigen-Antibody Reactions; Bromine; Chlorpromazine; Drug Hypersensitivity; Hu | 1972 |
5 other studies available for methoxsalen and Delayed Hypersensitivity
| Article | Year |
|---|---|
Enhancement of cutaneous delayed hypersensitivity reactions by a single exposure to UV-A or PUVA.
Topics: Antigens, Fungal; Candida albicans; Humans; Hypersensitivity, Delayed; Methoxsalen; Photochemotherap | 1982 |
DNA associated with the cell membrane is involved in the inhibition of the skin rejection response induced by infusions of photodamaged alloreactive cells that mediate rejection of skin allograft.
Topics: Animals; Cell Membrane; DNA; Female; Graft Rejection; Hypersensitivity, Delayed; Lymphocytes; Methox | 1992 |
Inhibition of anti-skin allograft immunity induced by infusions with photoinactivated effector T lymphocytes--the congenic model.
Topics: Animals; Cytotoxicity, Immunologic; Graft Survival; H-2 Antigens; Hypersensitivity, Delayed; Immune | 1991 |
Use of the occlusive patch to evaluate the photosensitive properties of chemicals in guinea-pigs.
Topics: Allergens; Animals; Coumarins; Dinitrobenzenes; Drug Evaluation, Preclinical; Guinea Pigs; Hypersens | 1985 |
Intensified contact sensitization to benzyl salicylate. Phototoxic effects of topical psoralen therapy.
Topics: Adolescent; Adult; Child; Dermatitis, Contact; Erythema; Female; Humans; Hypersensitivity, Delayed; | 1971 |