methoxsalen has been researched along with Cystic Fibrosis in 2 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methoxsalen failed to increase I(sc)." | 1.30 | Psoralens: novel modulators of Cl- secretion. ( Bridges, RJ; Devor, DC; Frizzell, RA; Singh, AK, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicolis, E | 1 |
| Lampronti, I | 1 |
| Dechecchi, MC | 1 |
| Borgatti, M | 1 |
| Tamanini, A | 1 |
| Bezzerri, V | 1 |
| Bianchi, N | 1 |
| Mazzon, M | 1 |
| Mancini, I | 1 |
| Giri, MG | 1 |
| Rizzotti, P | 1 |
| Gambari, R | 1 |
| Cabrini, G | 1 |
| Devor, DC | 1 |
| Singh, AK | 1 |
| Bridges, RJ | 1 |
| Frizzell, RA | 1 |
2 other studies available for methoxsalen and Cystic Fibrosis
| Article | Year |
|---|---|
Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen.
Topics: 5-Methoxypsoralen; Argemone; Bronchi; Cell Line; Cell Proliferation; Cystic Fibrosis; Epithelial Cel | 2009 |
Psoralens: novel modulators of Cl- secretion.
Topics: Animals; Atropine; Benzimidazoles; Calcium; Carbachol; Cell Line; Chloride Channels; Chlorides; Chlo | 1997 |