methoxsalen has been researched along with Chronic Disease in 36 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data indicate that in bath-PUVA treatment the use of a high (5 mg/L) methoxsalen concentration is substantially more effective in clearing chronic plaque-type psoriasis than a low (1 mg/L) concentration." | 9.12 | Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis. ( Hönigsmann, H; Konschitzky, R; Seeber, A; Tanew, A; Treitl, C; Vongthongsri, R, 2006) |
| "Our data indicate that in bath-PUVA treatment the use of a high (5 mg/L) methoxsalen concentration is substantially more effective in clearing chronic plaque-type psoriasis than a low (1 mg/L) concentration." | 5.12 | Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis. ( Hönigsmann, H; Konschitzky, R; Seeber, A; Tanew, A; Treitl, C; Vongthongsri, R, 2006) |
| "We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions." | 4.95 | Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017) |
| "No increased risk of skin cancer was evidenced in the four studies specifically assessing the potential carcinogenic risk of NB-UVB." | 2.48 | Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review. ( Aractingi, S; Archier, E; Aubin, F; Bachelez, H; Castela, E; Cribier, B; Devaux, S; Gallini, A; Joly, P; Jullien, D; Le Maître, M; Misery, L; Ortonne, JP; Paul, C; Richard, MA, 2012) |
| "A 45-year-old male with chronic myelocytic leukemia who received a bone marrow transplantation from a phenotypically HLA-matched unrelated donor developed chronic GVHD on day 100 post transplantation." | 1.29 | A case of chronic GVHD following bone marrow transplantation from a phenotypically HLA-matched unrelated donor. ( Sano, Y; Shimao, S; Tanaka, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (27.78) | 18.7374 |
| 1990's | 9 (25.00) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Buder, K | 1 |
| Zirngibl, M | 1 |
| Bapistella, S | 1 |
| Meerpohl, JJ | 1 |
| Strahm, B | 1 |
| Bassler, D | 1 |
| Weitz, M | 1 |
| Alsuliman, T | 1 |
| Magro, L | 1 |
| Coiteux, V | 1 |
| Gauthier, J | 1 |
| Srour, M | 1 |
| Lionet, A | 1 |
| Beauvais, D | 1 |
| Yakoub-Agha, I | 1 |
| Eccleston, C | 1 |
| Cooper, TE | 1 |
| Fisher, E | 1 |
| Anderson, B | 1 |
| Wilkinson, NM | 1 |
| Bojanic, I | 1 |
| Serventi Seiwerth, R | 1 |
| Golubic Cepulic, B | 1 |
| Mazic, S | 1 |
| Lukic, M | 1 |
| Raos, M | 1 |
| Plenkovic, F | 1 |
| Golemovic, M | 1 |
| Dubravcic, K | 1 |
| Perkovic, S | 1 |
| Batinic, D | 1 |
| Labar, B | 1 |
| Mok, ZR | 1 |
| Tan, ES | 1 |
| Chong, WS | 1 |
| Tzaneva, S | 1 |
| Kittler, H | 1 |
| Thallinger, C | 1 |
| Hönigsmann, H | 3 |
| Tanew, A | 3 |
| Perotti, C | 1 |
| Del Fante, C | 1 |
| Tinelli, C | 1 |
| Viarengo, G | 1 |
| Scudeller, L | 1 |
| Zecca, M | 1 |
| Locatelli, F | 1 |
| Salvaneschi, L | 1 |
| Inzinger, M | 1 |
| Heschl, B | 1 |
| Weger, W | 1 |
| Hofer, A | 1 |
| Legat, FJ | 1 |
| Gruber-Wackernagel, A | 1 |
| Tilz, H | 1 |
| Salmhofer, W | 1 |
| Quehenberger, F | 1 |
| Wolf, P | 1 |
| Archier, E | 2 |
| Devaux, S | 2 |
| Castela, E | 2 |
| Gallini, A | 2 |
| Aubin, F | 2 |
| Le Maître, M | 2 |
| Aractingi, S | 2 |
| Bachelez, H | 2 |
| Cribier, B | 2 |
| Joly, P | 2 |
| Jullien, D | 2 |
| Misery, L | 2 |
| Paul, C | 2 |
| Ortonne, JP | 2 |
| Richard, MA | 2 |
| Markham, T | 1 |
| Rogers, S | 3 |
| Collins, P | 2 |
| Petering, H | 1 |
| Breuer, C | 1 |
| Herbst, R | 1 |
| Kapp, A | 1 |
| Werfel, T | 1 |
| van Coevorden, AM | 1 |
| Kamphof, WG | 1 |
| van Sonderen, E | 1 |
| Bruynzeel, DP | 1 |
| Coenraads, PJ | 1 |
| Vongthongsri, R | 1 |
| Konschitzky, R | 1 |
| Seeber, A | 2 |
| Treitl, C | 1 |
| Sand, M | 1 |
| Bechara, FG | 1 |
| Sand, D | 1 |
| Radenhausen, M | 1 |
| Tomi, NS | 1 |
| Altmeyer, P | 1 |
| Hoffmann, K | 1 |
| Jansén, CT | 1 |
| Karvonen, J | 1 |
| Malmiharju, T | 1 |
| Epstein, JH | 1 |
| Hawk, JL | 1 |
| Grice, PL | 1 |
| Sano, Y | 1 |
| Tanaka, K | 1 |
| Shimao, S | 1 |
| Streit, V | 1 |
| Thiede, R | 1 |
| Wiedow, O | 1 |
| Christophers, E | 1 |
| Schempp, CM | 1 |
| Müller, H | 1 |
| Czech, W | 1 |
| Schöpf, E | 1 |
| Simon, JC | 1 |
| Gritiyarangsan, P | 1 |
| Sukhum, A | 1 |
| Tresukosol, P | 1 |
| Kullavanijaya, P | 1 |
| Der-Petrossian, M | 1 |
| Douwes, KE | 1 |
| Karrer, S | 1 |
| Abels, C | 1 |
| Landthaler, M | 1 |
| Szeimies, RM | 1 |
| Marks, J | 1 |
| Shuster, S | 1 |
| Briffa, DV | 1 |
| Warin, A | 1 |
| Greaves, M | 1 |
| Robertson, DB | 1 |
| McCarty, JR | 1 |
| Jarratt, M | 1 |
| Kalamkarian, AA | 1 |
| Marzeeva, GI | 1 |
| Mordovtsev, VN | 1 |
| Chistiakova, IA | 1 |
| Kirsanova, MM | 2 |
| Hofmann, C | 1 |
| Weissmann, I | 1 |
| Plewig, G | 1 |
| Layton, AM | 1 |
| Sheehan-Dare, R | 1 |
| Cunliffe, WJ | 1 |
| Yokel, BK | 1 |
| Hood, AF | 1 |
| Morison, WL | 1 |
| Iakubovich, AI | 1 |
| Krivatkin, SL | 1 |
| Lassus, A | 1 |
| Lauharanta, J | 1 |
| Eskelinen, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP): A Randomised Clinical Trial[NCT02347501] | Phase 2 | 118 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for methoxsalen and Chronic Disease
| Article | Year |
|---|---|
Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in children and adolescents.
Topics: Adolescent; Child; Chronic Disease; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; | 2022 |
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp | 2017 |
Efficacy of psoralen UV-A therapy vs. narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.
Topics: Chronic Disease; Humans; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psoriasis; Randomi | 2012 |
Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.
Topics: Chronic Disease; Female; Humans; Male; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psor | 2012 |
Phototoxicity and photoallergy in man.
Topics: Acute Disease; Allergens; Anti-Infective Agents; Antigen-Antibody Complex; Chronic Disease; Dermatit | 1983 |
15 trials available for methoxsalen and Chronic Disease
| Article | Year |
|---|---|
Treatment of chronic GVHD with extracorporeal photochemotherapy.
Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Female; Graft vs Host Disease; Humans; Leukapheresi | 2013 |
Oral vs. bath PUVA using 8-methoxypsoralen for chronic palmoplantar eczema.
Topics: Administration, Oral; Adult; Chronic Disease; Dose-Response Relationship, Radiation; Eczema; Female; | 2009 |
Narrowband UV-B (TL-01) phototherapy vs oral 8-methoxypsoralen psoralen-UV-A for the treatment of chronic plaque psoriasis.
Topics: Administration, Oral; Adult; Chronic Disease; Female; Humans; Male; Methoxsalen; Middle Aged; Photos | 2003 |
Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy.
Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Baths; Capsules; Chronic Disease; Eczema; Female | 2004 |
Randomized, double-blind comparison of 1 mg/L versus 5 mg/L methoxsalen bath-PUVA therapy for chronic plaque-type psoriasis.
Topics: Adult; Chronic Disease; Double-Blind Method; Female; Humans; Male; Methoxsalen; Middle Aged; Psorias | 2006 |
Extracorporeal photopheresis as a treatment for patients with severe, refractory atopic dermatitis.
Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Male; Methoxsalen; Middle Aged; Photopheresis; | 2007 |
PUVA therapy for polymorphous light eruptions: comparison of systemic methoxsalen and topical trioxsalen regimens and evaluation of local protective mechanisms.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Baths; Chronic Disease; Drug | 1982 |
Topical PUVA therapy for chronic hand eczema.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chronic Disease; Eczema; Female; Hand Dermatoses; | 1998 |
Half-side comparison study on the efficacy of 8-methoxypsoralen bath-PUVA versus narrow-band ultraviolet B phototherapy in patients with severe chronic atopic dermatitis.
Topics: Adult; Chronic Disease; Dermatitis, Atopic; Humans; Methoxsalen; PUVA Therapy; Treatment Outcome; Ul | 2000 |
Comparison of photochemotherapy and dithranol in the treatment of chronic plaque psoriasis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anthracenes; Anthralin; Chronic Di | 1979 |
Treatment of psoriasis with 8-methoxypsoralen and sunlight.
Topics: Administration, Topical; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Evaluation | 1978 |
[1st attempt at photochemotherapy of psoriasis in the USSR].
Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Methoxsalen; Mid | 1979 |
Bath-water compared with oral delivery of 8-methoxypsoralen PUVA therapy for chronic plaque psoriasis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Baths; Chronic Disease; Female; Hu | 1992 |
A double-blind, placebo-controlled trial of topical PUVA in persistent palmoplantar pustulosis.
Topics: Administration, Topical; Chronic Disease; Double-Blind Method; Foot; Hand; Humans; Methoxsalen; Psor | 1991 |
The effect of etretinate compared with different regimens of PUVA in the treatment of persistent palmoplantar pustulosis.
Topics: Chronic Disease; Etretinate; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methoxsalen; Mi | 1985 |
16 other studies available for methoxsalen and Chronic Disease
| Article | Year |
|---|---|
The concurrent administration of imatinib with extracorporeal photopheresis leads to complete and durable responses in patients with refractory sclerotic type chronic graft-versus-host disease.
Topics: Adrenal Cortex Hormones; Adult; Chronic Disease; Combined Modality Therapy; Drug Resistance; Female; | 2020 |
Treatment of cutaneous plasmacytosis with mask-bath PUVA: A therapeutic option.
Topics: Adult; Baths; Chronic Disease; Humans; Hypergammaglobulinemia; Male; Methoxsalen; Photosensitizing A | 2017 |
Extracorporeal photochemotherapy in graft-versus-host disease: a longitudinal study on factors influencing the response and survival in pediatric patients.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Chronic Disease; Disease-Free Survival; Female; | 2010 |
Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registry.
Topics: 5-Methoxypsoralen; Adult; Aged; Antibodies, Monoclonal; Biological Products; Chronic Disease; Combin | 2011 |
Comparison of localized high-dose UVA1 irradiation versus topical cream psoralen-UVA for treatment of chronic vesicular dyshidrotic eczema.
Topics: Administration, Topical; Adult; Aged; Chronic Disease; Dosage Forms; Eczema, Dyshidrotic; Female; Hu | 2004 |
The efficacy of localized PUVA therapy for chronic hand and foot dermatoses.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Chronic Disease; Fe | 1994 |
A case of chronic GVHD following bone marrow transplantation from a phenotypically HLA-matched unrelated donor.
Topics: Bone Marrow Transplantation; Chronic Disease; Graft vs Host Disease; Histocompatibility; Humans; Leu | 1994 |
Foil bath PUVA in the treatment of prurigo simplex subacuta.
Topics: Adult; Aged; Aged, 80 and over; Baths; Chronic Disease; Female; Humans; Male; Methoxsalen; Middle Ag | 1996 |
Treatment of chronic palmoplantar eczema with local bath-PUVA therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baths; Chronic Disease; Eczema; Female; Foot Dermatoses; | 1997 |
Does smoking influence the efficacy of bath-PUVA therapy in chronic palmoplantar eczema?
Topics: Adult; Aged; Baths; Chronic Disease; Eczema; Eczema, Dyshidrotic; Female; Humans; Keratosis; Male; M | 2000 |
[Pityriasis lichenoides chronica--a new indication for PUVA therapy? (author's transl)].
Topics: Administration, Oral; Adult; Chronic Disease; Drug Evaluation; Female; Humans; Male; Methoxsalen; Ph | 1979 |
[Treatment of psoriasis by photochemotherapy using a Soviet long-wave ultraviolet unit].
Topics: Adult; Chronic Disease; Female; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Photochemothe | 1979 |
Editorial: Photochemotherapy for psoriasis.
Topics: Animals; Chronic Disease; DNA Repair; Guinea Pigs; Humans; Methoxsalen; Mice; Psoriasis; Ultraviolet | 1975 |
Management of chronic photosensitive eczema.
Topics: Chronic Disease; Eczema; Female; Humans; Methoxsalen; Middle Aged; Photosensitivity Disorders; PUVA | 1990 |
[Late results of photochemotherapy of patients with psoriasis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chronic Disease; Drug Therapy, Combination; Female; Foll | 1990 |
[Comparative characteristics of the results of photochemotherapy with the external use of psoberan in patients with psoriasis].
Topics: Administration, Oral; Baths; Chronic Disease; Drug Combinations; Drug Evaluation; Ficusin; Furocouma | 1988 |