methoxsalen has been researched along with Cataract in 18 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapy with methoxsalen and type A (long-wavelength) ultraviolet radiation (PUVA) has recently become a common method of treating psoriasis and other dermatologic conditions." | 3.67 | Lens opacities appearing during therapy with methoxsalen and long-wavelength ultraviolet radiation. ( Grenier, R; Lafond, G; Roy, PE, 1984) |
| "Psoralen photoproducts were identified in association with cataracts in a psoriatic patient several years after oral methoxsalen plus ultraviolet A light (PUVA) therapy." | 3.67 | Lenticular psoralen photoproducts and cataracts of a PUVA-treated psoriatic patient. ( Anderson, TF; Lerman, S; Wong, JM; Wong, RC; Woo, TY, 1985) |
| "Unilateral aphakia or pseudophakia was induced surgically and the eyes were allowed to heal." | 1.27 | Photobinding of 3H 8-methoxypsoralen to monkey intraocular tissues. ( Franks, Y; Gammon, A; Gardner, K; Lerman, S; Megaw, J; Takei, Y, 1984) |
| "No cataracts were seen in any of the animals." | 1.26 | Dermatological and ocular examinations in rabbits chronically photosensitized with methoxsalen. ( Cheng, HM; Chylack, LT; Krugler, J; Morison, WL; Nelson, WF; Parrish, JA; Pathak, MA; Woehler, ME, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (94.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bäck, O | 1 |
| Hollström, E | 1 |
| Lidén, S | 1 |
| Thorburn, W | 1 |
| Hammershøy, O | 1 |
| Jessen, F | 1 |
| Lerman, S | 4 |
| Megaw, J | 3 |
| Gardner, K | 3 |
| Takei, Y | 1 |
| Franks, Y | 1 |
| Gammon, A | 1 |
| Lafond, G | 1 |
| Roy, PE | 1 |
| Grenier, R | 1 |
| Parrish, JA | 2 |
| LeVine, MJ | 1 |
| Fitzpatrick, TB | 1 |
| Koch, HR | 2 |
| Beitzen, R | 1 |
| Kremer, F | 1 |
| Chioralia, G | 1 |
| Baurmann, H | 1 |
| Marqversen, J | 1 |
| Axelsen, I | 1 |
| Nielsen, E | 1 |
| Zachariae, H | 1 |
| Farber, EM | 1 |
| Glew, WB | 1 |
| Briffa, DV | 1 |
| Warin, AP | 2 |
| Chylack, LT | 1 |
| Woehler, ME | 1 |
| Cheng, HM | 1 |
| Pathak, MA | 1 |
| Morison, WL | 1 |
| Krugler, J | 1 |
| Nelson, WF | 1 |
| De Witte, E | 1 |
| Coppens, A | 1 |
| Missotten, L | 1 |
| Carruthers, JA | 1 |
| Barker, FM | 1 |
| Dayhaw-Barker, P | 1 |
| Forbes, PD | 1 |
| Davies, RE | 1 |
| Woo, TY | 1 |
| Wong, RC | 1 |
| Wong, JM | 1 |
| Anderson, TF | 1 |
4 reviews available for methoxsalen and Cataract
| Article | Year |
|---|---|
Oral methoxsalen photochemotherapy of psoriasis and mycosis fungoides.
Topics: Adolescent; Adult; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cataract; Child; Furoco | 1980 |
Determination of 8-methoxypsoralen in serum, aqueous, and lens: relation to long-wave ultraviolet phototoxicity in experimental and clinical photochemotherapy.
Topics: Adolescent; Adult; Aged; Animals; Aqueous Humor; Biological Assay; Cataract; Female; Humans; Lens, C | 1979 |
Photochemotherapy in psoriasis: a review.
Topics: Animals; Cataract; Humans; Methoxsalen; Mutagens; Photochemotherapy; Psoriasis; Rats; Skin Diseases; | 1979 |
Editorial: Photochemotherapy in psoriasis.
Topics: Animals; Cataract; Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mice; Nausea; Pruritus; P | 1976 |
14 other studies available for methoxsalen and Cataract
| Article | Year |
|---|---|
Absence of cataract ten years after treatment with 8-methoxypsoralen.
Topics: Adult; Aged; Cataract; Humans; Methoxsalen; Middle Aged; Photochemotherapy; Vitiligo | 1980 |
A retrospective study of cataract formation in 96 patients treated with PUVA.
Topics: Adolescent; Adult; Aged; Cataract; Female; Humans; Male; Methoxsalen; Middle Aged; Ophthalmoscopy; P | 1982 |
Photobinding of 3H 8-methoxypsoralen to monkey intraocular tissues.
Topics: Animals; Aphakia; Autoradiography; Cataract; Darkness; Eye; Luminescent Measurements; Macaca mulatta | 1984 |
Lens opacities appearing during therapy with methoxsalen and long-wavelength ultraviolet radiation.
Topics: Adult; Aged; Cataract; Eye Protective Devices; Female; Humans; Male; Methoxsalen; Middle Aged; Photo | 1984 |
8-methoxypsoralen and long ultraviolet effects on the rat lens: experiments with high dosage.
Topics: Animals; Cataract; Corneal Opacity; Dose-Response Relationship, Drug; Eye Diseases; Lens, Crystallin | 1982 |
Psoralen--long-wave ultraviolet therapy and human cataractogenesis.
Topics: Adult; Animals; Cataract; DNA; Eye Proteins; Humans; Methoxsalen; Photochemotherapy; PUVA Therapy; R | 1982 |
8-methoxypsoralen and the eye.
Topics: Aged; Aqueous Humor; Cataract; Cataract Extraction; Humans; Methoxsalen; Middle Aged; Tritium | 1981 |
Psoralen and ultraviolet A (PUVA)--a critique.
Topics: Carcinoma, Basal Cell; Cataract; Humans; Keratosis; Methoxsalen; Photochemotherapy; Psoriasis; Risk; | 1980 |
British Photodermatology Group guidelines for PUVA.
Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis; | 1994 |
Dermatological and ocular examinations in rabbits chronically photosensitized with methoxsalen.
Topics: Animals; Cataract; Eye Protective Devices; Female; Lens, Crystalline; Methoxsalen; Photochemotherapy | 1979 |
[Could PUVA therapy and solar lights provoke ocular lesions?].
Topics: Animals; Cataract; Eye Protective Devices; Eyeglasses; Guinea Pigs; Humans; Lens, Crystalline; Metho | 1979 |
[Photochemotherapy and cataract formation].
Topics: Animals; Cataract; Guinea Pigs; Humans; Lens, Crystalline; Methoxsalen; Mice; Photochemotherapy; Pso | 1978 |
Ocular effects of treatment with various psoralen derivatives and ultraviolet-A (UVA) radiation in HRA/Skh hairless mice.
Topics: 5-Methoxypsoralen; Animals; Cataract; Corneal Opacity; Eye; Furocoumarins; Methoxsalen; Mice; Mice, | 1986 |
Lenticular psoralen photoproducts and cataracts of a PUVA-treated psoriatic patient.
Topics: Adult; Cataract; Humans; Lens, Crystalline; Male; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Th | 1985 |