methoxsalen has been researched along with Carcinoma, Epidermoid in 21 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 18 squamous cell carcinomas of the skin were reported in 2975 PUVA-treated patients until 1987." | 1.28 | Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report. ( Berne, B; Larkö, O; Lindelöf, B; Sigurgeirsson, B; Tegner, E, 1992) |
| "Histopathologically, some tumors were squamous cell carcinomas." | 1.27 | Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1 with longwave ultraviolet light. ( Nagayo, K; Song, PS; Tran, RM; Way, BH, 1983) |
| "Most of the tumors were rapidly growing squamous cell carcinomas giving metastases in 20% of the animals." | 1.26 | 5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation. ( Bisagni, E; Zajdela, F, 1981) |
| "Multiple lesions of Bowen's disease and squamous cell carcinoma on the penis and pubic areas developed in a 32-year-old patient with psoriasis who was undergoing treatment with psoralen and long-wave ultraviolet radiation (PUVA)." | 1.26 | Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy. ( Tam, DW; Urbach, F; Van Scott, EJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yan, X | 1 |
| Wu, J | 1 |
| Chen, J | 1 |
| Lambertini, L | 1 |
| Surin, K | 1 |
| Ton, TV | 1 |
| Clayton, N | 1 |
| Dunnick, JK | 1 |
| Kim, Y | 1 |
| Hong, HH | 1 |
| Devereux, TR | 1 |
| Sills, RC | 1 |
| Nagayo, K | 2 |
| Way, BH | 1 |
| Tran, RM | 1 |
| Song, PS | 1 |
| Parrish, JA | 2 |
| LeVine, MJ | 1 |
| Fitzpatrick, TB | 2 |
| Zajdela, F | 1 |
| Bisagni, E | 1 |
| Mäkinen, M | 1 |
| Forbes, PD | 1 |
| Stenbäck, F | 1 |
| Schindl, A | 1 |
| Klosner, G | 1 |
| Hönigsmann, H | 1 |
| Jori, G | 1 |
| Calzavara-Pinton, PC | 1 |
| Trautinger, F | 1 |
| Liu, Z | 1 |
| Lu, Y | 1 |
| Lebwohl, M | 1 |
| Wei, H | 1 |
| Stern, RS | 1 |
| Thibodeau, LA | 1 |
| Kleinerman, RA | 1 |
| Epstein, JH | 1 |
| Tam, DW | 1 |
| Van Scott, EJ | 1 |
| Urbach, F | 1 |
| Verdich, J | 1 |
| Harber, LC | 1 |
| Mortazawi, SA | 1 |
| Fry, RJ | 2 |
| Ley, RD | 2 |
| Grube, DD | 2 |
| Lindelöf, B | 1 |
| Sigurgeirsson, B | 1 |
| Tegner, E | 1 |
| Larkö, O | 1 |
| Berne, B | 1 |
| Goldoft, MJ | 1 |
| Weiss, NS | 1 |
| Torinuki, W | 1 |
| Tagami, H | 1 |
1 review available for methoxsalen and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Oral methoxsalen photochemotherapy of psoriasis and mycosis fungoides.
Topics: Adolescent; Adult; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cataract; Child; Furoco | 1980 |
20 other studies available for methoxsalen and Carcinoma, Epidermoid
| Article | Year |
|---|---|
[Inhibitory effects of 8-methoxypsoralen combining with all trans retinoic acid on oral squamous cancer cell lines].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Division; Cell Line, | 1998 |
Analysis of p53 tumor suppressor gene, H-ras protooncogene and proliferating cell nuclear antigen (PCNA) in squamous cell carcinomas of HRA/Skh mice following exposure to 8-methoxypsoralen (8-MOP) and UVA radiation (PUVA therapy).
Topics: Animals; Carcinoma, Squamous Cell; DNA Mutational Analysis; DNA, Neoplasm; Genes, p53; Genes, ras; H | 2005 |
Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1 with longwave ultraviolet light.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Squamous Cell; Methoxsalen; Mice; Neoplas | 1983 |
5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation.
Topics: 5-Methoxypsoralen; Animals; Carcinogens; Carcinoma, Squamous Cell; DNA Repair; Female; Male; Methoxs | 1981 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fle | 1997 |
Flow cytometric quantification of UV-induced cell death in a human squamous cell carcinoma-derived cell line: dose and kinetic studies.
Topics: Annexin A5; Carcinoma, Squamous Cell; Cell Death; Dose-Response Relationship, Radiation; Flow Cytome | 1998 |
PUVA (8-methoxy-psoralen plus ultraviolet A) induces the formation of 8-hydroxy-2'-deoxyguanosine and DNA fragmentation in calf thymus DNA and human epidermoid carcinoma cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinoma, Squamous Cell; Cattle; Deoxyguanosine; DNA; DNA Dam | 1999 |
Does photochemotherapy increase the risk of skin cancer?
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; | 1979 |
Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis.
Topics: Administration, Oral; Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Hum | 1979 |
Risks and benefits of the treatment of psoriasis.
Topics: Administration, Oral; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Coal Tar; Furocoumar | 1979 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; M | 1979 |
Squamous cell carcinoma. Occurrence in mycosis fungoides treated with psoralens plus long-wave ultraviolet radiation.
Topics: Aged; Carcinoma, Squamous Cell; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungo | 1979 |
PUVA therapy status.
Topics: Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultravi | 1979 |
[Treatment of basaliomas and spinaliomas with the local use of 8-MOP and black light].
Topics: Administration, Topical; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Fe | 1979 |
Photosensitized reactions and carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA; Female; Methoxsalen; Mice; Mice, Nude; Neo | 1978 |
Photosensitizing effects of 8-methoxypsoralen on the skin of hairless mice--II. Strain and spectral differences for tumorigenesis.
Topics: Animals; Carcinoma, Squamous Cell; DNA; Dose-Response Relationship, Radiation; Epidermis; Female; Me | 1977 |
Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Humans; Male; Methoxsalen; PUVA Thera | 1992 |
Incidence of male genital skin tumors: lack of increase in the United States.
Topics: Carcinoma, Squamous Cell; Genital Neoplasms, Male; Humans; Incidence; Male; Methoxsalen; Penile Neop | 1992 |
[Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Squamous Cell; Keratosis; Methoxsalen; Mice; Photosens | 1987 |
Incidence of skin cancer in Japanese psoriatic patients treated with either methoxsalen phototherapy, Goeckerman regimen, or both therapies. A 10-year follow-up study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Jap | 1988 |