methoxsalen has been researched along with Carcinoma, Basal Cell in 9 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Carcinoma, Basal Cell: A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A child was treated from age 18 months to 8 years with oral methoxsalen and ultraviolet A radiation (PUVA) for refractory psoriasis." | 4.79 | Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study. ( Nichols, KT; Stern, RS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parrish, JA | 2 |
| LeVine, MJ | 1 |
| Fitzpatrick, TB | 2 |
| Farber, EM | 1 |
| Stern, RS | 2 |
| Nichols, KT | 1 |
| Hannuksela-Svahn, A | 1 |
| Pukkala, E | 1 |
| Koulu, L | 1 |
| Jansén, CT | 1 |
| Karvonen, J | 1 |
| Thibodeau, LA | 1 |
| Kleinerman, RA | 1 |
| Epstein, JH | 1 |
| Mortazawi, SA | 1 |
| Moller, R | 1 |
| Howitz, J | 1 |
2 reviews available for methoxsalen and Carcinoma, Basal Cell
| Article | Year |
|---|---|
Oral methoxsalen photochemotherapy of psoriasis and mycosis fungoides.
Topics: Adolescent; Adult; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cataract; Child; Furoco | 1980 |
Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study.
Topics: Administration, Oral; Adolescent; Carcinoma, Basal Cell; Follow-Up Studies; Humans; Male; Methoxsale | 1996 |
7 other studies available for methoxsalen and Carcinoma, Basal Cell
| Article | Year |
|---|---|
Psoralen and ultraviolet A (PUVA)--a critique.
Topics: Carcinoma, Basal Cell; Cataract; Humans; Keratosis; Methoxsalen; Photochemotherapy; Psoriasis; Risk; | 1980 |
Cancer incidence among Finnish psoriasis patients treated with 8-methoxypsoralen bath PUVA.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Baths; Carcinoma, Basal Cell; | 1999 |
Does photochemotherapy increase the risk of skin cancer?
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; | 1979 |
Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis.
Topics: Administration, Oral; Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Hum | 1979 |
Risks and benefits of the treatment of psoriasis.
Topics: Administration, Oral; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Coal Tar; Furocoumar | 1979 |
[Treatment of basaliomas and spinaliomas with the local use of 8-MOP and black light].
Topics: Administration, Topical; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Fe | 1979 |
Methoxsalen and multiple basal cell carcinomas.
Topics: Adult; Arsenic; Carcinoma, Basal Cell; Cocarcinogenesis; Female; Humans; Methoxsalen; Skin Neoplasms | 1976 |