methoxsalen has been researched along with Cancer of Skin in 160 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In search of such a drug, we examined the efficacy of graveoline, a bioactive compound isolated from Ruta graveolens on skin melanoma A375 cells through the use of specific signaling cascades and their inhibitors." | 7.80 | Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. ( Bishayee, K; Ghosh, S; Khuda-Bukhsh, AR, 2014) |
| "Photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is an effective treatment for psoriasis." | 7.69 | Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study. ( Nichols, KT; Stern, RS; Väkevä, LH, 1997) |
| "Methoxsalen photochemotherapy (PUVA; psoralen plus ultraviolet light) is effective in the treatment of mycosis fungoides (MF)." | 7.66 | Methoxsalen photochemotherapy for mycosis fungoides. ( Gilchrest, BA, 1979) |
| "The cutaneous manifestations of mycosis fungoides have been successfully treated in nine patients for 16 to 28 months with oral methoxsalen and subsequent irradiation with longwave ultraviolet light." | 7.65 | Oral methoxsalen photochemotherapy of mycosis fungoides. ( Fitzpatrick, TB; Gilchrest, BA; Haynes, HA; Parrish, JA; Tanenbaum, L, 1976) |
| "Photochemotherapy using methoxsalen in combination with long-wave ultraviolet light (PUVA) is an essential modality in the treatment of various skin diseases." | 4.80 | PUVA therapy: current concerns in Japan. ( Danno, K, 1999) |
| "A child was treated from age 18 months to 8 years with oral methoxsalen and ultraviolet A radiation (PUVA) for refractory psoriasis." | 4.79 | Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study. ( Nichols, KT; Stern, RS, 1996) |
| "The combination of methoxsalen and long-wave UV radiation (UV-A) is being used on a large scale in clinical practice to treat a variety of dermatoses, particularly psoriasis." | 4.76 | Mutagenicity and carcinogenicity of methoxsalen plus UV-A. ( Roelandts, R, 1984) |
| " In search of such a drug, we examined the efficacy of graveoline, a bioactive compound isolated from Ruta graveolens on skin melanoma A375 cells through the use of specific signaling cascades and their inhibitors." | 3.80 | Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. ( Bishayee, K; Ghosh, S; Khuda-Bukhsh, AR, 2014) |
| "Oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is a highly effective therapy for psoriasis and many other skin conditions." | 3.71 | The risk of melanoma in association with long-term exposure to PUVA. ( Stern, RS, 2001) |
| "Photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is an effective treatment for psoriasis." | 3.69 | Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study. ( Nichols, KT; Stern, RS; Väkevä, LH, 1997) |
| " It is advocated as a means of determining an individual's relative risk of skin tumors and has been used to determine the initial therapeutic dose of UV radiation for UV-B phototherapy or oral methoxsalen photochemotherapy (PUVA) for psoriasis." | 3.67 | Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy. ( Momtaz, K; Stern, RS, 1984) |
| "Kaposi's varicelliform eruption, caused by herpes simplex type 1, developed in a patient with mycosis fungoides four days after initiation of photochemotherapy with methoxsalen plus long-wave ultraviolet light (PUVA)." | 3.66 | Kaposi's varicelliform eruption in mycosis fungoides. ( Segal, RJ; Watson, W, 1978) |
| "Methoxsalen photochemotherapy (PUVA; psoralen plus ultraviolet light) is effective in the treatment of mycosis fungoides (MF)." | 3.66 | Methoxsalen photochemotherapy for mycosis fungoides. ( Gilchrest, BA, 1979) |
| "Nine patients with stages 2 or 3 mycosis fungoides (MF) and one with Sézary's syndrome were treated with oral methoxsalen and long-wave ultraviolet light." | 3.66 | Photochemotherapy for mycosis fungoides: a clinical and histological study. ( Cripps, DJ; Dufton, PA; Lowe, NJ; Vickers, CF, 1979) |
| "Six patients with mycosis fungoides were treated with methoxsalen and long-wave ultraviolet light." | 3.65 | Photochemotherapy in mycosis fungoides. ( Bleehen, S; Gange, RW; Hodge, L; Vella Briffa, D; Warin, AP, 1977) |
| "The cutaneous manifestations of mycosis fungoides have been successfully treated in nine patients for 16 to 28 months with oral methoxsalen and subsequent irradiation with longwave ultraviolet light." | 3.65 | Oral methoxsalen photochemotherapy of mycosis fungoides. ( Fitzpatrick, TB; Gilchrest, BA; Haynes, HA; Parrish, JA; Tanenbaum, L, 1976) |
| " Fourteen patients (all male) aged 38 to 72 years with CTCL of the mycosis fungoides type, stage IIa/IIb, and a 72-year-old male patient with a Ki-1 lymphoma were treated twice a month for 6 months with extracorporeal photochemotherapy using oral 8-methoxypsoralen as photosensitizer in combination with interferon alfa-2a subcutaneously 3 times a week in the maximal tolerable dosage (ie, up to 18 x 10(6) U)." | 2.70 | Treatment of stage II cutaneous T-cell lymphoma with interferon alfa-2a and extracorporeal photochemotherapy: a prospective controlled trial. ( Hipler, UC; Knopf, B; Koch, HJ; Liebold, K; Looks, A; Meyer, J; Wollina, U, 2001) |
| "There is an increased risk of skin cancer following PUVA, shown by both US and European studies." | 2.48 | Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review. ( Aractingi, S; Archier, E; Aubin, F; Bachelez, H; Castela, E; Cribier, B; Devaux, S; Gallini, A; Joly, P; Jullien, D; Le Maître, M; Misery, L; Ortonne, JP; Paul, C; Richard, MA, 2012) |
| "X-rays are an effective treatment for skin cancers." | 1.62 | Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice. ( Al-Chaer, RN; Glud, M; Lerche, CM; Philipsen, PA; Wulf, HC, 2021) |
| " Safety was assessed using reports of adverse device effects (ADEs) and unanticipated ADEs (UADEs), device malfunctions and defects, vital signs, laboratory parameters and physical examinations." | 1.35 | Safety of a new, single, integrated, closed photopheresis system in patients with cutaneous T-cell lymphoma. ( Bisaccia, E; Geskin, L; Vonderheid, EC, 2009) |
| "Hypericin is a photodynamic compound activated by either visible (400-700 nm) or UVA (320-400 nm) light, and has been shown to inhibit the growth of a variety of neoplastic cell types." | 1.30 | Photoactivated hypericin is an anti-proliferative agent that induces a high rate of apoptotic death of normal, transformed, and malignant T lymphocytes: implications for the treatment of cutaneous lymphoproliferative and inflammatory disorders. ( Fox, FE; Niu, Z; Rook, AH; Tobia, A, 1998) |
| " In serum, peak 8-MOP concentrations were reached < or =40 min following ingestion; the half-life of 8-MOP in the serum was 50+/-14 min (n=7)." | 1.30 | Pharmacokinetics of 8-methoxypsoralen during extracorporeal photopheresis. ( Nestle, FO; Panizzon, R; Shephard, SE, 1999) |
| "One psoriatic patient developed Bowen's disease." | 1.29 | Cutaneous carcinoma and PUVA lentigines in Thai patients treated with oral PUVA. ( Gritiyarangsan, P; Kullavanijaya, P; Rungrairatanaroj, P; Sindhavananda, J, 1995) |
| "A total of 18 squamous cell carcinomas of the skin were reported in 2975 PUVA-treated patients until 1987." | 1.28 | Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report. ( Berne, B; Larkö, O; Lindelöf, B; Sigurgeirsson, B; Tegner, E, 1992) |
| "The number of chromosomal aberrations and SCE were increased upon treatment, but only transiently, returning to basal levels between consecutive treatments." | 1.28 | Cytogenetic effects during extracorporeal photopheresis treatment of two patients with cutaneous T-cell lymphoma. ( Gebauer, HJ; Küster, W; Meschig, R; Peterseim, UM; Plewig, G, 1991) |
| "Histopathologically, some tumors were squamous cell carcinomas." | 1.27 | Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1 with longwave ultraviolet light. ( Nagayo, K; Song, PS; Tran, RM; Way, BH, 1983) |
| " All test groups developed atypical squamous papillomas in direct proportion to the dosage of UVA radiation received." | 1.27 | Psoralen-containing sunscreen is tumorigenic in hairless mice. ( Cartwright, LE; Walter, JF, 1983) |
| " In one patient who showed a lower absorption rate of 8-MOP plasma levels varied from 0-126 ng/ml." | 1.26 | Intraindividual variations of 8-methoxypsoralen plasma levels. ( Korting, HC; Schäfer-Korting, M, 1982) |
| "Most of the tumors were rapidly growing squamous cell carcinomas giving metastases in 20% of the animals." | 1.26 | 5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation. ( Bisagni, E; Zajdela, F, 1981) |
| "Multiple lesions of Bowen's disease and squamous cell carcinoma on the penis and pubic areas developed in a 32-year-old patient with psoriasis who was undergoing treatment with psoralen and long-wave ultraviolet radiation (PUVA)." | 1.26 | Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy. ( Tam, DW; Urbach, F; Van Scott, EJ, 1979) |
| "Mycosis fungoides is a cutaneously-derived malignant lymphoma which, without effective treatment, may run an unrelenting, rapidly lethal course." | 1.26 | Mycosis fungoides: clinical and therapeutic review. ( Basler, RS; Lynch, PJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (58.75) | 18.7374 |
| 1990's | 40 (25.00) | 18.2507 |
| 2000's | 14 (8.75) | 29.6817 |
| 2010's | 9 (5.63) | 24.3611 |
| 2020's | 3 (1.88) | 2.80 |
| Authors | Studies |
|---|---|
| Lerche, CM | 1 |
| Al-Chaer, RN | 1 |
| Glud, M | 1 |
| Philipsen, PA | 1 |
| Wulf, HC | 1 |
| Nakahashi, K | 1 |
| Nihira, K | 1 |
| Suzuki, M | 1 |
| Ishii, T | 1 |
| Masuda, K | 1 |
| Mori, K | 1 |
| Hoang, M | 1 |
| Qureshi, A | 1 |
| Oancea, E | 1 |
| Cho, E | 1 |
| Trautinger, F | 3 |
| Holien, T | 1 |
| Gederaas, OA | 1 |
| Darvekar, SR | 1 |
| Christensen, E | 1 |
| Peng, Q | 1 |
| Ghosh, S | 1 |
| Bishayee, K | 1 |
| Khuda-Bukhsh, AR | 1 |
| Zic, JA | 2 |
| Chowdhari, S | 1 |
| Saini, N | 1 |
| Bisaccia, E | 2 |
| Vonderheid, EC | 1 |
| Geskin, L | 1 |
| Kofoed, K | 1 |
| Schiødt, I | 1 |
| Gniadecki, R | 1 |
| Archier, E | 1 |
| Devaux, S | 1 |
| Castela, E | 1 |
| Gallini, A | 1 |
| Aubin, F | 1 |
| Le Maître, M | 1 |
| Aractingi, S | 1 |
| Bachelez, H | 1 |
| Cribier, B | 1 |
| Joly, P | 1 |
| Jullien, D | 1 |
| Misery, L | 1 |
| Paul, C | 1 |
| Ortonne, JP | 2 |
| Richard, MA | 1 |
| Whittaker, S | 1 |
| Ortiz, P | 1 |
| Dummer, R | 1 |
| Ranki, A | 1 |
| Hasan, B | 1 |
| Meulemans, B | 1 |
| Gellrich, S | 1 |
| Knobler, R | 4 |
| Stadler, R | 1 |
| Karrasch, M | 1 |
| Crovetti, G | 1 |
| Carabelli, A | 1 |
| Berti, E | 1 |
| Guizzardi, M | 1 |
| Fossati, S | 1 |
| De Filippo, C | 1 |
| Bertani, E | 1 |
| Chignell, CF | 1 |
| Haseman, JK | 1 |
| Sik, RH | 1 |
| Tennant, RW | 1 |
| Trempus, CS | 1 |
| GRIFFIN, AC | 4 |
| HAKIM, RE | 2 |
| KNOX, JM | 2 |
| SPOOR, HJ | 1 |
| MEYERZUMBUESCHENFELDE, KH | 1 |
| WULF, K | 1 |
| MACDONALD, EJ | 2 |
| HOPKINS, CE | 2 |
| SMITH, L | 1 |
| GARRETT, H | 1 |
| BLACK, GL | 1 |
| BELISARIO, JC | 1 |
| DAVIS, CT | 1 |
| Carneiro Leite, V | 1 |
| Ferreira Santos, R | 1 |
| Chen Chen, L | 1 |
| Andreu Guillo, L | 1 |
| Lambertini, L | 1 |
| Surin, K | 1 |
| Ton, TV | 1 |
| Clayton, N | 1 |
| Dunnick, JK | 1 |
| Kim, Y | 1 |
| Hong, HH | 1 |
| Devereux, TR | 1 |
| Sills, RC | 1 |
| Weber, F | 1 |
| Schmuth, M | 1 |
| Sepp, N | 1 |
| Fritsch, P | 1 |
| Wackernagel, A | 1 |
| Hofer, A | 1 |
| Legat, F | 1 |
| Kerl, H | 2 |
| Wolf, P | 2 |
| Ogino, J | 1 |
| Saga, K | 1 |
| Kagaya, M | 1 |
| Kamada, A | 1 |
| Hirosaki, K | 1 |
| Kaneko, R | 1 |
| Jimbow, K | 1 |
| Kilinc Karaarslan, I | 1 |
| Teban, L | 1 |
| Dawid, M | 1 |
| Tanew, A | 1 |
| Kittler, H | 1 |
| Vagace, JM | 1 |
| Gervasini, G | 1 |
| Morais, F | 1 |
| Benitez, J | 1 |
| Alonso, N | 1 |
| de Argila, D | 1 |
| Arranz, I | 1 |
| Bajo, R | 1 |
| Cao, H | 1 |
| Hearst, JE | 1 |
| Corash, L | 1 |
| Wang, Y | 1 |
| Becker, SW | 1 |
| Roelandts, R | 1 |
| Nagayo, K | 2 |
| Way, BH | 1 |
| Tran, RM | 1 |
| Song, PS | 1 |
| Halprin, KM | 1 |
| Comerford, M | 1 |
| Taylor, JR | 1 |
| Magnus, IA | 5 |
| Young, AR | 10 |
| Stern, RS | 7 |
| Momtaz, K | 1 |
| Pathak, MA | 1 |
| Davies, AC | 1 |
| Smith, NP | 1 |
| Cartwright, LE | 1 |
| Walter, JF | 1 |
| Shimada, S | 1 |
| Kawashima, M | 1 |
| Watanabe, S | 1 |
| Yamada, K | 1 |
| Mizoguchi, M | 1 |
| Hori, Y | 1 |
| Kukita, A | 1 |
| Parrish, JA | 4 |
| LeVine, MJ | 1 |
| Fitzpatrick, TB | 4 |
| Fry, RJ | 3 |
| Ley, RD | 3 |
| Grube, D | 1 |
| Staffeldt, E | 1 |
| Schäfer-Korting, M | 1 |
| Korting, HC | 1 |
| Zajdela, F | 2 |
| Bisagni, E | 2 |
| Epenetos, AA | 1 |
| Dubroff, LM | 1 |
| Farber, EM | 1 |
| Forlot, P | 1 |
| Kersey, P | 1 |
| Grupper, C | 1 |
| Beretti, B | 1 |
| Hook, I | 1 |
| Halder, RM | 1 |
| Battle, EF | 1 |
| Smith, EM | 1 |
| Stivala, LA | 1 |
| Pizzala, R | 2 |
| Rossi, R | 1 |
| Melli, R | 1 |
| Verri, MG | 1 |
| Bianchi, L | 2 |
| Bunn, PA | 1 |
| Marschalkó, M | 1 |
| Soós, G | 1 |
| Berecz, M | 1 |
| Pálóczy, K | 1 |
| Rácz, I | 1 |
| Knobler, RM | 2 |
| Graninger, W | 1 |
| Macheiner, W | 1 |
| Gruenwald, C | 1 |
| Neumann, R | 1 |
| Ramer, W | 1 |
| Lim, HW | 1 |
| Edelson, RL | 3 |
| Müllegger, R | 1 |
| Cerroni, L | 1 |
| Aigner, R | 1 |
| Fueger, G | 1 |
| Höfler, G | 1 |
| Derbaschnig, J | 1 |
| Nataraj, AJ | 1 |
| Black, HS | 1 |
| Ananthaswamy, HN | 1 |
| Gritiyarangsan, P | 1 |
| Sindhavananda, J | 1 |
| Rungrairatanaroj, P | 1 |
| Kullavanijaya, P | 1 |
| Duvic, M | 1 |
| Hester, JP | 1 |
| Lemak, NA | 1 |
| Stricklin, GP | 2 |
| Greer, JP | 1 |
| Kinney, MC | 1 |
| Shyr, Y | 1 |
| Wilson, DC | 1 |
| King, LE | 2 |
| Nichols, KT | 2 |
| Mäkinen, M | 1 |
| Forbes, PD | 5 |
| Stenbäck, F | 2 |
| Väkevä, LH | 1 |
| Fox, FE | 1 |
| Niu, Z | 1 |
| Tobia, A | 1 |
| Rook, AH | 1 |
| Balogh, A | 1 |
| Merkel, U | 1 |
| Looks, A | 2 |
| Vollandt, R | 1 |
| Wollina, U | 2 |
| Lunder, EJ | 1 |
| Danno, K | 1 |
| Shephard, SE | 2 |
| Nestle, FO | 1 |
| Panizzon, R | 1 |
| Hannuksela-Svahn, A | 1 |
| Pukkala, E | 1 |
| Koulu, L | 1 |
| Jansén, CT | 1 |
| Karvonen, J | 1 |
| Panizzon, RG | 1 |
| Monti, P | 1 |
| Inga, A | 1 |
| Aprile, A | 1 |
| Campomenosi, P | 1 |
| Menichini, P | 1 |
| Ottaggio, L | 1 |
| Viaggi, S | 1 |
| Ghigliotti, G | 1 |
| Abbondandolo, A | 1 |
| Fronza, G | 1 |
| Meyer, J | 1 |
| Knopf, B | 1 |
| Koch, HJ | 1 |
| Liebold, K | 1 |
| Hipler, UC | 1 |
| Molin, L | 1 |
| Skogh, M | 1 |
| Volden, G | 2 |
| Husby, G | 1 |
| Schmitt, D | 1 |
| Alario, A | 1 |
| Thivolet, J | 1 |
| Zachariae, H | 1 |
| Kragballe, K | 1 |
| Søgaard, H | 1 |
| Pembroke, AC | 1 |
| Hehir, ME | 1 |
| du Vivier, AW | 1 |
| Marten, RH | 1 |
| Mourelatos, DC | 1 |
| Spittle, MF | 1 |
| Minna, JD | 1 |
| Roenigk, HH | 3 |
| Glatstein, E | 1 |
| Greaves, MW | 1 |
| Hofmann, C | 1 |
| Burg, G | 1 |
| Plewig, G | 3 |
| Braun-Falco, O | 1 |
| Urbach, F | 5 |
| Segal, RJ | 1 |
| Watson, W | 1 |
| Dubertret, L | 2 |
| Averbeck, D | 2 |
| Moustacchi, E | 1 |
| Touraine, R | 1 |
| Latarjet, R | 1 |
| Briffa, DV | 2 |
| Warin, AP | 6 |
| Thibodeau, LA | 2 |
| Kleinerman, RA | 1 |
| Epstein, JH | 1 |
| Tam, DW | 1 |
| Van Scott, EJ | 1 |
| Basler, RS | 1 |
| Lynch, PJ | 1 |
| Gilchrest, BA | 2 |
| Thomsen, K | 1 |
| Mackie, RM | 1 |
| Morgan, RW | 1 |
| Spellman, CW | 1 |
| Harrington, CI | 1 |
| Bleehen, SS | 2 |
| Niemi, KM | 1 |
| Verdich, J | 1 |
| Ashwood-Smith, MJ | 1 |
| Harber, LC | 1 |
| Mortazawi, SA | 1 |
| Vella Briffa, D | 3 |
| Calnan, CD | 1 |
| Brückner, V | 1 |
| Hodge, L | 1 |
| Gange, RW | 1 |
| Bleehen, S | 1 |
| Gilchrest, B | 1 |
| Parrish, J | 1 |
| Konrad, K | 1 |
| Grube, DD | 2 |
| Davies, RE | 3 |
| Lowe, NJ | 1 |
| Cripps, DJ | 1 |
| Dufton, PA | 1 |
| Vickers, CF | 1 |
| Carruthers, JA | 1 |
| Tanenbaum, L | 1 |
| Haynes, HA | 1 |
| Hjortshoj, A | 1 |
| Schmidt, H | 1 |
| Moller, R | 1 |
| Howitz, J | 1 |
| Laksmipathi, T | 1 |
| Gould, P | 1 |
| Johnson, BE | 1 |
| Mackenzie, LA | 1 |
| Frain-Bell, W | 1 |
| Heald, P | 2 |
| Rook, A | 1 |
| Perez, M | 1 |
| Wintroub, B | 2 |
| Jegasothy, B | 2 |
| Gasparro, F | 2 |
| Berger, C | 3 |
| Edelson, R | 2 |
| Agin, P | 1 |
| Lerner, AB | 1 |
| Lindelöf, B | 1 |
| Sigurgeirsson, B | 1 |
| Tegner, E | 1 |
| Larkö, O | 1 |
| Berne, B | 1 |
| Zic, J | 1 |
| Arzubiaga, C | 1 |
| Salhany, KE | 1 |
| Parker, RA | 1 |
| Wilson, D | 1 |
| Greer, J | 1 |
| Goldoft, MJ | 1 |
| Weiss, NS | 1 |
| Hornicek, FJ | 1 |
| Malinin, GI | 1 |
| Malinin, TI | 1 |
| Lo, HK | 1 |
| Fossel, ET | 1 |
| Fletcher, JG | 1 |
| McDonagh, J | 1 |
| Hui, KK | 1 |
| Laskin, JD | 1 |
| Lee, E | 1 |
| Peterseim, UM | 1 |
| Küster, W | 1 |
| Gebauer, HJ | 1 |
| Meschig, R | 1 |
| Reeve, VE | 1 |
| Greenoak, GE | 1 |
| Boehm-Wilcox, C | 1 |
| Canfield, PJ | 1 |
| Gallagher, CH | 1 |
| Walker, SL | 2 |
| Kinley, JS | 1 |
| Plastow, SR | 1 |
| Morlière, P | 1 |
| Armus, S | 1 |
| Keyes, B | 1 |
| Cahill, C | 1 |
| Crater, D | 1 |
| Scarborough, D | 1 |
| Klainer, A | 1 |
| Heald, PW | 1 |
| Perez, MI | 1 |
| Gasparro, FP | 1 |
| Gibbs, NK | 3 |
| Hönigsmann, H | 2 |
| Santamaria, L | 1 |
| Bianchi, A | 1 |
| Arnaboldi, A | 1 |
| Ravetto, C | 1 |
| Andreoni, L | 1 |
| Santagati, G | 1 |
| Bermond, P | 1 |
| Garmyn, M | 1 |
| Torinuki, W | 1 |
| Tagami, H | 1 |
| Vonderheid, E | 1 |
| Wolff, K | 1 |
| Hannuksela, M | 1 |
| Lahti, A | 1 |
| Bridges, BA | 1 |
| Douglas, WS | 1 |
| Railton, R | 1 |
| Newman, PN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label, Single-cohort, and Single-center Phase II Study Evaluating Tumor-specific Immunity After Extracorporeal Photopheresis in Patients With Sézary Syndrome at Single-cell Resolution[NCT05157581] | 15 participants (Anticipated) | Observational | 2023-04-04 | Recruiting | |||
| A Randomized, Open-Label Phase III Trial to Evaluate the Efficacy and Safety of Bexarotene (Targretin) Capsules Combined With PUVA, Compared to PUVA Treatment Alone in Patients With Mycosis Fungoides[NCT00056056] | Phase 3 | 93 participants (Actual) | Interventional | 2003-01-31 | Terminated (stopped due to poor accrual) | ||
| Adaption of the Skin Sun Sensitivity Scale for People With All Pigment Varieties[NCT01975038] | 292 participants (Actual) | Observational | 2013-10-31 | Completed | |||
| A Single Arm Study of Extracorporeal Photoimmune Therapy With Uvadex For Corticosteroid Sparing in Patients With Corticosteroid-Dependent Crohn's Disease Who May Also Be Refractory or Intolerant to Immunosuppressants and/or Anti-Tumor Necrosis Factor Agen[NCT00056355] | Phase 1 | 10 participants | Interventional | 2003-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
22 reviews available for methoxsalen and Cancer of Skin
| Article | Year |
|---|---|
Phototherapy of mycosis fungoides.
Topics: Combined Modality Therapy; Dermatologic Agents; Humans; Methoxsalen; Mycosis Fungoides; Photosensiti | 2017 |
Phototherapy of cutaneous T-cell lymphomas.
Topics: Humans; Lymphoma, T-Cell, Cutaneous; Lymphomatoid Papulosis; Methoxsalen; Mycosis Fungoides; Photose | 2018 |
Extracorporeal Photopheresis in the Treatment of Mycosis Fungoides and Sézary Syndrome.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Humans; Immunomodulation; Methoxsalen; Mycosis Fungoi | 2015 |
[Documented effect of extra corporeal photopheresis on T-cell mediated diseases].
Topics: Evidence-Based Medicine; Graft vs Host Disease; Humans; Lymphoma, T-Cell, Cutaneous; Methoxsalen; Ph | 2011 |
Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review.
Topics: Chronic Disease; Female; Humans; Male; Methoxsalen; Photochemotherapy; Photosensitizing Agents; Psor | 2012 |
Mutagenicity and carcinogenicity of methoxsalen plus UV-A.
Topics: Animals; Carcinogens; Guinea Pigs; Humans; Hypersensitivity, Delayed; Immunosuppression Therapy; In | 1984 |
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; beta Carotene; Carotenoids; Chloro | 1982 |
Oral methoxsalen photochemotherapy of psoriasis and mycosis fungoides.
Topics: Adolescent; Adult; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cataract; Child; Furoco | 1980 |
Studies on the multistage nature of radiation carcinogenesis.
Topics: Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Radiation; Harderian Gland; Huma | 1982 |
Photopheresis for the treatment of cutaneous T-cell lymphoma.
Topics: Humans; Lymphoma, T-Cell, Cutaneous; Methoxsalen; Photopheresis; Skin Neoplasms | 1995 |
Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study.
Topics: Administration, Oral; Adolescent; Carcinoma, Basal Cell; Follow-Up Studies; Humans; Male; Methoxsale | 1996 |
PUVA therapy: current concerns in Japan.
Topics: Humans; Japan; Methoxsalen; Photosensitizing Agents; PUVA Therapy; Skin Diseases; Skin Neoplasms | 1999 |
Report of the Committee on Therapy for Mycosis Fungoides and Sézary Syndrome.
Topics: Administration, Topical; Antineoplastic Agents; Drug Therapy, Combination; Humans; Methoxsalen; Myco | 1979 |
Dermatology.
Topics: Acne Vulgaris; Anti-Bacterial Agents; Humans; Methoxsalen; Psoriasis; Rosacea; Skin Diseases; Skin D | 1976 |
Photochemotherapy in psoriasis: a review.
Topics: Animals; Cataract; Humans; Methoxsalen; Mutagens; Photochemotherapy; Psoriasis; Rats; Skin Diseases; | 1979 |
Editorial: Photochemotherapy in psoriasis.
Topics: Animals; Cataract; Coumarins; Ficusin; Furocoumarins; Humans; Methoxsalen; Mice; Nausea; Pruritus; P | 1976 |
The Seiji memorial lecture. Pigment stories: from vitiligo to melanomas and points in between.
Topics: Adult; Female; Humans; Hydroquinones; Male; Melanoma; Melanosis; Methoxsalen; Nevus, Pigmented; Para | 1992 |
Photopheresis: present and future aspects.
Topics: Animals; Humans; Immune System Diseases; Immunotherapy; Lymphocyte Depletion; Lymphoma, T-Cell, Cuta | 1991 |
Photocarcinogenicity of psoralens used in PUVA treatment: present status in mouse and man.
Topics: Animals; Carcinogens; Furocoumarins; Humans; Methoxsalen; Photochemotherapy; Skin Neoplasms | 1990 |
Effects of chemicals on photobiologic reactions of skin.
Topics: Animals; Carcinogens; Humans; Methoxsalen; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agent | 1990 |
Aspects of psoralen phototumorigenesis with emphasis on the possible role of tumour promotion.
Topics: Animals; Cross-Linking Reagents; DNA; Furocoumarins; Methoxsalen; Neoplasms, Experimental; Ornithine | 1986 |
Psoralen photochemotherapy--mechanisms, drugs, toxicity.
Topics: DNA; Erythema; Furocoumarins; Humans; Methoxsalen; Neoplasms, Radiation-Induced; Photosensitivity Di | 1986 |
5 trials available for methoxsalen and Cancer of Skin
| Article | Year |
|---|---|
Efficacy and safety of bexarotene combined with psoralen-ultraviolet A (PUVA) compared with PUVA treatment alone in stage IB-IIA mycosis fungoides: final results from the EORTC Cutaneous Lymphoma Task Force phase III randomized clinical trial (NCT00056056
Topics: Adolescent; Adult; Aged; Anticarcinogenic Agents; Bexarotene; Child; Child, Preschool; Combined Moda | 2012 |
Plasma and buffy coat concentration of 8-methoxypsoralen in patients treated with extracorporeal photopheresis.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Female; Humans; Leukapheresis; Lymphoma, T-Cell; M | 1998 |
Treatment of stage II cutaneous T-cell lymphoma with interferon alfa-2a and extracorporeal photochemotherapy: a prospective controlled trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Humans; Injections, Subcutaneous; Interfer | 2001 |
[Photochemotherapy of cutaneous lymphoma: oral and local 8-MOP-UVA treatment (author's transl)].
Topics: Aged; Dermatitis, Exfoliative; Female; Humans; Keratoderma, Palmoplantar; Lymphatic Diseases; Lympho | 1977 |
Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. Preliminary results.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Female; Humans; Lymphoma; Male; Methoxs | 1987 |
133 other studies available for methoxsalen and Cancer of Skin
| Article | Year |
|---|---|
Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice.
Topics: Animals; Immunocompromised Host; Kaplan-Meier Estimate; Methoxsalen; Mice; Mice, Hairless; Neoplasms | 2021 |
A novel mouse model of cutaneous T-cell lymphoma revealed the combined effect of mogamulizumab with psoralen and ultraviolet a therapy.
Topics: Animals; Ficusin; Lymphoma, T-Cell, Cutaneous; Methoxsalen; Mice; Mycosis Fungoides; PUVA Therapy; S | 2022 |
Furocoumarins potentiate UVA-induced DNA damage in skin melanocytes.
Topics: Citrus; DNA Damage; Furocoumarins; Humans; Melanocytes; Methoxsalen; Skin Neoplasms; Ultraviolet Ray | 2023 |
Comparison between 8-methoxypsoralen and 5-aminolevulinic acid in killing T cells of photopheresis patients ex vivo.
Topics: Aminolevulinic Acid; Cell Culture Techniques; Graft vs Host Disease; Humans; Lymphoma, T-Cell, Cutan | 2018 |
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Humans; Me | 2014 |
Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes.
Topics: Apoptosis; DEAD Box Protein 58; DEAD-box RNA Helicases; Gene Expression Profiling; Humans; Interfero | 2016 |
Safety of a new, single, integrated, closed photopheresis system in patients with cutaneous T-cell lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Administration Schedule; Equ | 2009 |
Photopheresis in cutaneous T-cell lymphoma: five-year experience.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Interferon-alpha; Lymphoma, T-Cell, Cutaneous; M | 2000 |
Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen.
Topics: Animals; Animals, Genetically Modified; Carcinogenicity Tests; Dose-Response Relationship, Drug; Fem | 2003 |
Methoxsalen in ultraviolet carcinogenesis in the mouse.
Topics: Animals; Carcinogenesis; Furans; Methoxsalen; Mice; Skin Neoplasms; Ultraviolet Rays | 1959 |
Erythema and tumor formation in methoxsalen-treated mice exposed to flourescent light.
Topics: Animals; Dermatitis, Phototoxic; Erythema; Humans; Light; Methoxsalen; Mice; Neoplasms; Photosensiti | 1960 |
Effect of topical hormones and other dermatologicals on melanin pigment.
Topics: Humans; Keratosis; Melanins; Methoxsalen; Nevus; Nevus, Pigmented; Pigmentation Disorders; Skin Neop | 1963 |
[EXPERIMENTAL STUDIES ON THE EFFECT OF PHOTODYNAMIC REACTIONS ON THE PATHOGENESIS OF LIGHT CARCINOMA].
Topics: Dermatitis, Phototoxic; Khellin; Light; Methoxsalen; Neoplasms, Experimental; Photosensitivity Disor | 1963 |
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL I.
Topics: Ficusin; Geriatrics; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology | 1963 |
PSORALEN PROPHYLAXIS AGAINST SKIN CANCER: REPORT OF CLINICAL TRIAL II.
Topics: Ficusin; Humans; Methoxsalen; Neoplasms; Skin Neoplasms; Sunburn; Toxicology | 1963 |
Protection from ultraviolet carcinogenesis.
Topics: 4-Aminobenzoic Acid; Biomedical Research; Carcinogenesis; Humans; Methoxsalen; Skin Neoplasms; Sulfo | 1960 |
Psoralen derivatives and longwave ultraviolet irradiation are active in vitro against human melanoma cell line.
Topics: Cell Division; Cell Line; Cisplatin; Colorimetry; Cross-Linking Reagents; DNA; Dose-Response Relatio | 2004 |
Analysis of p53 tumor suppressor gene, H-ras protooncogene and proliferating cell nuclear antigen (PCNA) in squamous cell carcinomas of HRA/Skh mice following exposure to 8-methoxypsoralen (8-MOP) and UVA radiation (PUVA therapy).
Topics: Animals; Carcinoma, Squamous Cell; DNA Mutational Analysis; DNA, Neoplasm; Genes, p53; Genes, ras; H | 2005 |
Bath-water PUVA therapy with 8-methoxypsoralen in mycosis fungoides.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Baths; Female; Humans; Male; Methoxsal | 2005 |
Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoides.
Topics: 5-Methoxypsoralen; Adult; Aged; Aged, 80 and over; Epidemiologic Methods; Female; Humans; Male; Meth | 2006 |
CD30+ large cell transformation of mycosis fungoides after psoralen plus ultraviolet A photochemotherapy.
Topics: Aged; Female; Humans; Lymphoma, Large-Cell, Anaplastic; Male; Methoxsalen; Mycosis Fungoides; PUVA T | 2007 |
Changes in the dermoscopic appearance of melanocytic naevi after photochemotherapy or narrow-band ultraviolet B phototherapy.
Topics: Adult; Dermoscopy; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Male; Met | 2007 |
Retinal toxic reactions following photopheresis.
Topics: Chorioretinitis; Humans; Male; Methoxsalen; Middle Aged; Photopheresis; Photosensitizing Agents; Sez | 2007 |
LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells.
Topics: Chromatography, Liquid; DNA; DNA Adducts; DNA, Neoplasm; Humans; Melanoma; Methoxsalen; Skin Neoplas | 2008 |
Psoralen phototherapeutic agents.
Topics: Coumarins; Humans; Liver; Methoxsalen; Pigmentation Disorders; Skin Neoplasms; Substance-Related Dis | 1967 |
Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1 with longwave ultraviolet light.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Carcinoma, Squamous Cell; Methoxsalen; Mice; Neoplas | 1983 |
Skin cancer in patients treated with 8-methoxypsoralen plus longwave ultraviolet radiation.
Topics: Humans; Methoxsalen; Photochemotherapy; PUVA Therapy; Skin Neoplasms | 1984 |
Is psoralen-containing sunscreen tumorigenic in hairless mice?
Topics: 5-Methoxypsoralen; Animals; Methoxsalen; Mice; Mice, Hairless; Photochemotherapy; PUVA Therapy; Skin | 1984 |
Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy.
Topics: Administration, Oral; Humans; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Risk; Skin; S | 1984 |
A comparison of the phototumorigenic potential of 8-MOP and 5-MOP in hairless albino mice exposed to solar simulated radiation.
Topics: 5-Methoxypsoralen; Animals; Female; Male; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Radiation-In | 1983 |
Psoralen-containing sunscreen is tumorigenic in hairless mice.
Topics: 5-Methoxypsoralen; Animals; Cysts; Dose-Response Relationship, Drug; Female; Isomerism; Methoxsalen; | 1983 |
Methoxsalen.
Topics: Animals; Chemical Phenomena; Chemistry; Cocarcinogenesis; DNA; Female; Humans; Male; Methoxsalen; Mi | 1980 |
[Cell kinetic studies on human melanoma cell line (SEKI, II) under the effect of 8-methoxypsoralen with UVA irradiation (author's transl)].
Topics: Cell Cycle; Cell Line; Humans; Melanoma; Methoxsalen; Neoplasms, Experimental; Photochemotherapy; PU | 1980 |
The sunburn cell in hairless mouse epidermis: quantitative studies with UV-A radiation and mono- and bifunctional psoralens.
Topics: Animals; DNA; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Epidermal Cel | 1982 |
Intraindividual variations of 8-methoxypsoralen plasma levels.
Topics: Adult; Aged; Biological Availability; Female; Humans; Intestinal Absorption; Liver; Male; Metabolic | 1982 |
5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation.
Topics: 5-Methoxypsoralen; Animals; Carcinogens; Carcinoma, Squamous Cell; DNA Repair; Female; Male; Methoxs | 1981 |
Sunshine and malignant melanoma.
Topics: Humans; Melanoma; Methoxsalen; Skin Neoplasms; Sunlight; Sunscreening Agents | 1980 |
Psoralen and photoactivation.
Topics: Darkness; DNA; Humans; Methoxsalen; Photochemotherapy; Risk; Skin Neoplasms; Ultraviolet Therapy | 1980 |
Psoralen and ultraviolet A (PUVA)--a critique.
Topics: Carcinoma, Basal Cell; Cataract; Humans; Keratosis; Methoxsalen; Photochemotherapy; Psoriasis; Risk; | 1980 |
Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation.
Topics: Humans; Methoxsalen; Skin Neoplasms; Structure-Activity Relationship; Sunscreening Agents | 1980 |
Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation.
Topics: Humans; Methoxsalen; Skin Neoplasms; Sunscreening Agents | 1980 |
Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation.
Topics: Humans; Methoxsalen; Photochemotherapy; Skin Neoplasms; Sunscreening Agents | 1980 |
Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation.
Topics: Humans; Methoxsalen; Mutation; Perfume; Photosensitivity Disorders; Skin; Skin Neoplasms | 1980 |
Cutaneous malignancies in patients treated with psoralen photochemotherapy (PUVA) for vitiligo.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; F | 1995 |
Photoinduction of micronuclei by 4,4',6-trimethylangelicin and 8-methoxypsoralen in different experimental models.
Topics: Animals; Cell Survival; Cocarcinogenesis; Erythroid Precursor Cells; Female; Fibroblasts; Furocoumar | 1995 |
Cutaneous T cell lymphomas.
Topics: Administration, Topical; Humans; Lymphoma, T-Cell, Cutaneous; Mechlorethamine; Methoxsalen; Randomiz | 1994 |
British Photodermatology Group guidelines for PUVA.
Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis; | 1994 |
[Extracorporeal photopheresis in the therapy of Sézary syndrome].
Topics: Administration, Oral; Blood Component Transfusion; Chlorambucil; Combined Modality Therapy; Humans; | 1993 |
Parenteral administration of 8-methoxypsoralen in photopheresis.
Topics: Administration, Oral; Capsules; Cell Survival; Chromatography, High Pressure Liquid; Humans; Infusio | 1993 |
Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis.
Topics: 5-Methoxypsoralen; Dermatitis, Exfoliative; HIV Seronegativity; Humans; Interferon alpha-2; Interfer | 1996 |
Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Codon; Cross-Linking Reagents; DNA Damage; | 1996 |
Cutaneous carcinoma and PUVA lentigines in Thai patients treated with oral PUVA.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Arsenic; Bowen's Disease; Female; Follow | 1995 |
Photopheresis therapy for cutaneous T-cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Dermatitis, Exfoliative; Female; Follow-Up Studies; Forecasting; Hum | 1996 |
Long-term follow-up of patients with cutaneous T-cell lymphoma treated with extracorporeal photochemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Lymphoma, T-Cell, Cutaneous; Male | 1996 |
Quinolone antibacterials: a new class of photochemical carcinogens.
Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fle | 1997 |
Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). The PUVA Follow-Up Study.
Topics: Adult; Aged; Female; Humans; Male; Melanoma; Methoxsalen; Middle Aged; Odds Ratio; Prospective Studi | 1997 |
Photoactivated hypericin is an anti-proliferative agent that induces a high rate of apoptotic death of normal, transformed, and malignant T lymphocytes: implications for the treatment of cutaneous lymphoproliferative and inflammatory disorders.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Cells, Cultured; Humans; Keratitis; Lymphocyte Activa | 1998 |
Merkel-cell carcinomas in patients treated with methoxsalen and ultraviolet A radiation.
Topics: Aged; Aged, 80 and over; Carcinoma, Merkel Cell; Female; Humans; Male; Methoxsalen; Photosensitizing | 1998 |
Pharmacokinetics of 8-methoxypsoralen during extracorporeal photopheresis.
Topics: Adult; Aged; Biological Availability; Chromatography, High Pressure Liquid; Dose-Response Relationsh | 1999 |
Cancer incidence among Finnish psoriasis patients treated with 8-methoxypsoralen bath PUVA.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Baths; Carcinoma, Basal Cell; | 1999 |
Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; Baths; DNA Adducts; Female; Humans | 1999 |
p53 mutations experimentally induced by 8-methoxypsoralen plus UVA (PUVA) differ from those found in human skin cancers in PUVA-treated patients.
Topics: DNA Mutational Analysis; Genes, p53; Humans; Methoxsalen; Mutation; Plasmids; PUVA Therapy; Skin Neo | 2000 |
The risk of melanoma in association with long-term exposure to PUVA.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Female; Humans; Incidence; Male; Melanoma; Methoxsal | 2001 |
Successful PUVA-treatment in the tumour stage of mycosis fungoides associated with the appearance of lesions in organs other than the skin.
Topics: Drug Evaluation; Female; Humans; Lymphatic Metastasis; Male; Methoxsalen; Mycosis Fungoides; Photoch | 1978 |
Occurrence of immunoglobulins and complement in the skin of patients undergoing topical treatment of mycosis fungoides.
Topics: Complement System Proteins; Fluorescent Antibody Technique; Humans; Immunoglobulin A; Immunoglobulin | 1979 |
Does photochemotherapy increase the risk of skin cancer?
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; | 1979 |
Oral photochemotherapy in lichen planus (LP) and mycosis fungoides (MF): ultrastructural modifications of the infiltrating cells.
Topics: Cell Nucleus; Cytoplasm; Humans; Lichen Planus; Methoxsalen; Mycosis Fungoides; Necrosis; Photochemo | 1979 |
Liver biopsy in PUVA-treated patients.
Topics: Adult; Female; Humans; Liver; Male; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Psoriasis; Sk | 1979 |
Photochemotherapy and risk of skin cancer.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms | 1979 |
Photochemotherapy and the risk of skin cancer.
Topics: Carcinogens; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Risk; Skin Neoplasms | 1979 |
Mycosis fungoides: electron beam therapy in England.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Radiation Injuries; Radiotherapy, High-En | 1979 |
Experimental modification of photocarcinogenesis. III. Simulation of exposure to sunlight and fluorescent whitening agents.
Topics: Animals; Arylsulfonates; Infrared Rays; Methoxsalen; Mice; Mice, Nude; Neoplasms, Experimental; Neop | 1975 |
Kaposi's varicelliform eruption in mycosis fungoides.
Topics: Humans; Kaposi Varicelliform Eruption; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemo | 1978 |
Photochemotherapy (PUVA) of psoriasis using 3-carbethoxypsoralen, a non-carcinogenic compound in mice.
Topics: Animals; DNA, Fungal; Drug Evaluation, Preclinical; Female; Furocoumarins; Humans; Male; Methoxsalen | 1979 |
Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis.
Topics: Administration, Oral; Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Hum | 1979 |
Risks and benefits of the treatment of psoriasis.
Topics: Administration, Oral; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Coal Tar; Furocoumar | 1979 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; M | 1979 |
Mycosis fungoides: clinical and therapeutic review.
Topics: Humans; Lymphoma; Mechlorethamine; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Sezary Syndrom | 1979 |
Methoxsalen photochemotherapy for mycosis fungoides.
Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; Remissio | 1979 |
Photochemotherapy for mycosis fungoides: long-term followup study.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Precancerous Conditions; Remission, Spont | 1979 |
Scandinavian mycosis fungoides trial.
Topics: Administration, Topical; Antineoplastic Agents; Female; Humans; Male; Mechlorethamine; Methoxsalen; | 1979 |
Onycholysis occurring during PUVA therapy.
Topics: Female; Humans; Methoxsalen; Middle Aged; Mycosis Fungoides; Nail Diseases; Photochemotherapy; Skin | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultraviolet Therapy | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Animals; Humans; Methoxsalen; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Photochemothe | 1979 |
Skin cancer after PUVA treatment for psoriasis.
Topics: Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultraviolet Therapy | 1979 |
Photochemotherapy in mycosis fungoides--a study of fifty-six patients [proceedings].
Topics: Female; Humans; Male; Methoxsalen; Mycosis Fungoides; Neoplasm Staging; Photochemotherapy; Skin Neop | 1979 |
PUVA treatment in mycosis fungoides.
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Pho | 1979 |
Squamous cell carcinoma. Occurrence in mycosis fungoides treated with psoralens plus long-wave ultraviolet radiation.
Topics: Aged; Carcinoma, Squamous Cell; Furocoumarins; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungo | 1979 |
Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
Topics: Female; Humans; Male; Methoxsalen; Skin Neoplasms; Sunscreening Agents | 1979 |
PUVA therapy status.
Topics: Carcinoma, Squamous Cell; Humans; Methoxsalen; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultravi | 1979 |
[Treatment of basaliomas and spinaliomas with the local use of 8-MOP and black light].
Topics: Administration, Topical; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Fe | 1979 |
Parakeratosis variegata: a report of two cases and their treatment with PUVA.
Topics: Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Parapsoriasis; Photochemoth | 1979 |
Photosensitizers and radiosensitizers in dermatology and oncology.
Topics: Brain Neoplasms; DNA; Humans; Methoxsalen; Metronidazole; Misonidazole; Mycosis Fungoides; Photochem | 1979 |
Photochemotherapy in mycosis fungoides.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; S | 1977 |
Mycosis fungoides [proceedings].
Topics: Female; Humans; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; Skin Neoplasms | 1978 |
PUVA treatment of mycosis fungoides [proceedings].
Topics: Humans; Methoxsalen; Mycosis Fungoides; Photochemotherapy; Remission, Spontaneous; Skin Neoplasms | 1978 |
Photochemotherapy in mycosis fungoides.
Topics: Female; Humans; Male; Methoxsalen; Microscopy, Electron; Mycosis Fungoides; Photochemotherapy; Skin; | 1978 |
Photosensitized reactions and carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; DNA; Female; Methoxsalen; Mice; Mice, Nude; Neo | 1978 |
Interaction of light and chemicals in carcinogenesis.
Topics: Animals; Carcinogens; Cocarcinogenesis; Methoxsalen; Neoplasms, Experimental; Neoplasms, Radiation-I | 1978 |
Photochemotherapy for mycosis fungoides: a clinical and histological study.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Photochemotherapy; R | 1979 |
Oral methoxsalen photochemotherapy of mycosis fungoides.
Topics: Administration, Oral; Aged; Female; Humans; Male; Mechlorethamine; Methoxsalen; Middle Aged; Mycosis | 1976 |
Photochemotherapy of mycosis fungoides: Preliminary communication.
Topics: Administration, Oral; Aged; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Skin Neoplasm | 1977 |
Photochemotherapy for mycosis fungoides.
Topics: Adult; Aged; Female; Humans; Male; Methoxsalen; Middle Aged; Mycosis Fungoides; Skin Neoplasms; Ultr | 1977 |
Photosensitizing effects of 8-methoxypsoralen on the skin of hairless mice--II. Strain and spectral differences for tumorigenesis.
Topics: Animals; Carcinoma, Squamous Cell; DNA; Dose-Response Relationship, Radiation; Epidermis; Female; Me | 1977 |
Methoxsalen and multiple basal cell carcinomas.
Topics: Adult; Arsenic; Carcinoma, Basal Cell; Cocarcinogenesis; Female; Humans; Methoxsalen; Skin Neoplasms | 1976 |
Phototoxicity and photocarcinogenesis: comparative effects of anthracene and 8-methoxypsoralen in the skin of mice.
Topics: Animals; Anthracenes; Erythema; Methoxsalen; Mice; Neoplasms; Neoplasms, Experimental; Neoplasms, Ra | 1976 |
Experimental modification of photocarcinogenesis. II. Fluorescent whitening agents and simulated solar UVR.
Topics: Animals; Methoxsalen; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Photo | 1975 |
Proceedings: Photochemotherapy. A study of its efficacy in fifty patients suffering from psoriasis and other dermatoses.
Topics: Humans; Methoxsalen; Mycosis Fungoides; Parapsoriasis; Psoriasis; Skin Neoplasms; Ultraviolet Therap | 1976 |
Treatment of erythrodermic cutaneous T-cell lymphoma with extracorporeal photochemotherapy.
Topics: CD4-CD8 Ratio; Dermatitis, Exfoliative; Follow-Up Studies; Humans; Lymphoma, T-Cell, Cutaneous; Meth | 1992 |
Broad-spectrum protection in sunscreen products.
Topics: Benzoates; Camphor; Chalcones; Humans; Methoxsalen; Skin Neoplasms; Sunscreening Agents; Ultraviolet | 1992 |
Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Humans; Male; Methoxsalen; PUVA Thera | 1992 |
Extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Extracorporeal Circulation; Female; Human | 1992 |
Incidence of male genital skin tumors: lack of increase in the United States.
Topics: Carcinoma, Squamous Cell; Genital Neoplasms, Male; Humans; Incidence; Male; Methoxsalen; Penile Neop | 1992 |
Turnover of phospholipids in HUT 102 lymphoblasts and chromatographic characterization of purified lecithins after their exposure to long-wave UV light, psoralen, and UV light and psoralen.
Topics: Cell Line; Chromatography, Thin Layer; Humans; Lymphoma, T-Cell; Methoxsalen; Phosphatidylcholines; | 1992 |
Selective cytotoxicity of low-density lipoprotein to helper T cells of cutaneous T-cell lymphoma after photoperoxidation with 8-methoxypsoralen.
Topics: Cell Survival; Humans; Lipid Peroxidation; Lipoproteins, LDL; Methoxsalen; Photochemotherapy; Sezary | 1991 |
Psoralen binding and inhibition of epidermal growth factor binding by psoralen/ultraviolet light (PUVA) in human epithelial cells.
Topics: Binding, Competitive; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Methoxsalen; PUVA | 1991 |
Cytogenetic effects during extracorporeal photopheresis treatment of two patients with cutaneous T-cell lymphoma.
Topics: Administration, Oral; Aged; Chromosome Aberrations; Female; Humans; Lymphocytes; Lymphoma, T-Cell, C | 1991 |
Effect on topical 5-methoxypsoralen on tumorigenesis induced in albino and pigmented hairless mouse skin by UV irradiation.
Topics: 5-Methoxypsoralen; Albinism; Animals; Dose-Response Relationship, Radiation; Isomerism; Methoxsalen; | 1990 |
Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model.
Topics: 5-Methoxypsoralen; Animals; Carcinogens; Disease Models, Animal; Female; Humans; Methoxsalen; Mice; | 1990 |
Photopheresis for the treatment of cutaneous T cell lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Dermatitis, Exfoliative; Female; Humans; Leukapheresis; Lymphoma, T- | 1990 |
Dosage guidelines: extracorporeal photochemotherapy (photopheresis)
Topics: Humans; Lymphoma, T-Cell, Cutaneous; Methoxsalen; Photochemotherapy; Skin Neoplasms | 1990 |
Photopheresis.
Topics: Animals; Blood; Blood Component Removal; Drug Carriers; Humans; Liposomes; Lymphoma; Methoxsalen; Mi | 1990 |
PUVA treatment strategies and cancer risk.
Topics: Dose-Response Relationship, Drug; Humans; Methoxsalen; PUVA Therapy; Risk; Skin Neoplasms | 1986 |
[Photocarcinogenicity of 8-methoxypsoralen and aflatoxin B1].
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinoma, Squamous Cell; Keratosis; Methoxsalen; Mice; Photosens | 1987 |
Chemoprevention of indirect and direct chemical carcinogenesis by carotenoids as oxygen radical quenchers.
Topics: Animals; Benzo(a)pyrene; beta Carotene; Canthaxanthin; Carcinogens; Carotenoids; Diet; Female; Free | 1988 |
A first approach to an action spectrum for 8-MOP phototumorigenesis in mice.
Topics: Animals; DNA; Female; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Skin Neoplasm | 1988 |
Incidence of skin cancer in Japanese psoriatic patients treated with either methoxsalen phototherapy, Goeckerman regimen, or both therapies. A 10-year follow-up study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Jap | 1988 |
Photopheresis--extracorporeal irradiation of 8-MOP containing blood--a new therapeutic modality.
Topics: Combined Modality Therapy; Extracorporeal Circulation; Humans; Lymphoma; Methoxsalen; Plasmapheresis | 1987 |
Modification of 5-methoxypsoralen phototumorigenesis by UVB sunscreens: a statistical and histologic study in the hairless albino mouse.
Topics: 5-Methoxypsoralen; Animals; Female; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; | 1987 |
The carcinogenic properties of topical PUVA. A lifelong study in mice.
Topics: Animals; Carcinogens; Dose-Response Relationship, Radiation; Female; Furocoumarins; Methoxsalen; Mic | 1986 |
Interaction of ionizing radiation and 8-methoxypsoralen photosensitization: some implications for risk assessment.
Topics: Animals; Carcinogens; Methoxsalen; Mice; Mutation; Neoplasms, Radiation-Induced; Skin Neoplasms; Ult | 1985 |
Sunscreens and PUVA.
Topics: Erythema; Humans; Methoxsalen; PUVA Therapy; Skin Neoplasms; Spectrophotometry, Ultraviolet; Sunscre | 1985 |
Failure of UVR dose reciprocity for skin tumorigenesis in hairless mice treated with 8-methoxypsoralen.
Topics: Animals; Dose-Response Relationship, Drug; Female; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Rad | 1985 |