Page last updated: 2024-10-31

methoxsalen and Breast Neoplasms

methoxsalen has been researched along with Breast Neoplasms in 9 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"In MCF7 and ZR-75 breast cancer cells Bergapten exhibited anti-survival response by inducing the autophagic process increasing Beclin1, PI3KIII, UVRAG, AMBRA expression and conversion of LC3-I to LC3-II."1.42Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells. ( Andò, S; Aquila, S; De Amicis, F; Giordano, F; Guido, C; Mauro, L; Morelli, C; Nigro, A; Panno, ML; Perrotta, I; Santoro, M, 2015)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Amicis, F4
Aquila, S4
Morelli, C1
Guido, C2
Santoro, M2
Perrotta, I1
Mauro, L2
Giordano, F4
Nigro, A1
Andò, S5
Panno, ML5
Sisci, D3
Cione, E1
Vincenza, D1
Donà, A1
Tavolaro, P1
Martino, G1
Tavolaro, A1
Palma, MG2
Bartella, V2
Rago, V1
Maggiolini, M1
Lanzino, M1
Mastroianni, F1
Carpino, A1
Rizza, P1
Pellegrino, M1
Zito, D1
Giordano, C1
Catalano, S1
Vivacqua, A1
Fuqua, SW1
Prager, A1
Green, M1
Ben-Hur, E1
Sauter, C1
Santamaria, L1
Arnaboldi, A1
Daffara, P1
Bianchi, A1

Other Studies

9 other studies available for methoxsalen and Breast Neoplasms

ArticleYear
Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells.
    Molecular cancer, 2015, Jul-07, Volume: 14

    Topics: 5-Methoxypsoralen; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Gene Expres

2015
Bergapten induces metabolic reprogramming in breast cancer cells.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: 5-Methoxypsoralen; Breast Neoplasms; Cell Line, Tumor; Energy Metabolism; Female; Gene Expression Re

2016
Zeolite scaffolds for cultures of human breast cancer cells. Part II: Effect of pure and hybrid zeolite membranes on neoplastic and metastatic activity control.
    Materials science & engineering. C, Materials for biological applications, 2016, Nov-01, Volume: 68

    Topics: 5-Methoxypsoralen; Breast Neoplasms; Cell Culture Techniques; Doxorubicin; Female; Humans; MCF-7 Cel

2016
Evidence that bergapten, independently of its photoactivation, enhances p53 gene expression and induces apoptosis in human breast cancer cells.
    Current cancer drug targets, 2009, Volume: 9, Issue:4

    Topics: 5-Methoxypsoralen; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinas

2009
Breast cancer cell survival signal is affected by bergapten combined with an ultraviolet irradiation.
    FEBS letters, 2010, Jun-03, Volume: 584, Issue:11

    Topics: 5-Methoxypsoralen; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Humans; Insulin-Like Growth Fa

2010
Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination.
    Breast cancer research and treatment, 2012, Volume: 136, Issue:2

    Topics: 5-Methoxypsoralen; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dr

2012
Inhibition of ornithine decarboxylase induction by psoralen plus near ultraviolet light in human cells: the role of monoadducts vs DNA crosslinks.
    Photochemistry and photobiology, 1983, Volume: 37, Issue:5

    Topics: Breast Neoplasms; Carboxy-Lyases; Cell Line; DNA, Neoplasm; Enzyme Induction; Female; Humans; Methox

1983
[Heracl'eum mantegazzi'anum: photosensitization].
    Praxis, 2001, Jan-18, Volume: 90, Issue:3

    Topics: 5-Methoxypsoralen; Breast Neoplasms; Dermatitis, Contact; Diagnosis, Differential; Female; Humans; M

2001
Photocarcinogenesis by methoxypsoralen, neutral red and proflavine.
    Bollettino chimico farmaceutico, 1979, Volume: 118, Issue:7

    Topics: Acridines; Animals; Breast Neoplasms; Female; Methoxsalen; Mice; Neoplasms; Neutral Red; Phenazines;

1979