Page last updated: 2024-10-31

methoxsalen and Anasarca

methoxsalen has been researched along with Anasarca in 7 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Research Excerpts

ExcerptRelevanceReference
" Treatment with the cytochrome P-450 inhibitor cimetidine or 8-methoxypsoralen did not improve survival or reduce lung edema in rats exposed to 100% oxygen."3.68Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats. ( Hunt, CM; Kennedy, TP; Piantadosi, CA; Todd, NW; Whorton, AR, 1992)
"The results of the first six months of treatment of psoriasis with photochemotherapy in the Skin and Cancer Foundation's clinic resulted in 30 out of 53 patients being completely clear of psoriasis lesions, 14 showing progressive improvement (and subsequently clearing), four failures, and five withdrawals."1.26Photochemotherapy in psoriasis: the first six months in Australia. ( King, R; O'Brien, H; Paver, K; Poyzer, K, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chu, Z1
Xu, Q1
Zhu, Q1
Ma, X1
Mo, J1
Lin, G1
Zhao, Y1
Gu, Y1
Bian, L1
Shao, L1
Guo, J1
Ye, W1
Li, J1
He, G1
Xu, Y1
Shigehara, N1
Miyataka, H1
Kakegawa, H1
Nishiki, M1
Matsumoto, H1
Isobe, A1
Satoh, T1
King, R1
Poyzer, K1
Paver, K1
O'Brien, H1
Todd, NW1
Hunt, CM1
Kennedy, TP1
Piantadosi, CA1
Whorton, AR1
Gerberick, GF1
Ryan, CA1
Nash, JD1
Fusaro, RM1
Wolff, K1
Holubar, K1

Other Studies

7 other studies available for methoxsalen and Anasarca

ArticleYear
Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Animals; Boron Compounds; Calcitriol; Cyclic Nucleotide Phosphodiesterases, Type 4; Dermatitis, Atop

2021
Inflammatory action of 8-methoxypsoralen-spermine photoproduct (8-MOP-Spm-P(GFC)) and effects of various drugs on rat paw edema induced by 8-MOP-Spm-P(GFC).
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Erythrocytes; Hemolysis; Histamine Antagoni

1999
Photochemotherapy in psoriasis: the first six months in Australia.
    The Medical journal of Australia, 1979, Jan-13, Volume: 1, Issue:1

    Topics: Australia; Darier Disease; Dermatitis; Edema; Erythema; Humans; Methoxsalen; Photochemotherapy; Prur

1979
Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats.
    American journal of respiratory cell and molecular biology, 1992, Volume: 7, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Cimetidine; Cytochrome P-450 CYP1A1;

1992
A predictive mouse ear-swelling model for investigating topical phototoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:12

    Topics: Administration, Cutaneous; Animals; Data Interpretation, Statistical; Dose-Response Relationship, Dr

1989
A gravimetric technique for the analysis of acute ultraviolet damage.
    Acta dermato-venereologica, 1971, Volume: 51, Issue:5

    Topics: Animals; Biological Assay; Edema; Male; Methods; Methoxsalen; Organ Size; Photosensitivity Disorders

1971
[Phototoxic reaction to 8-methoxypsoralen. Ultrastructural changes in the epidermis].
    Archiv fur klinische und experimentelle Dermatologie, 1970, Volume: 237, Issue:1

    Topics: Animals; Cell Nucleus; Edema; Guinea Pigs; Leukocytes; Methoxsalen; Microscopy, Electron; Organoids;

1970