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methoxsalen and Adult Premature Aging Syndrome

methoxsalen has been researched along with Adult Premature Aging Syndrome in 1 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Research Excerpts

ExcerptRelevanceReference
"The clinical phenotype of Werner Syndrome (WRN) includes features reminiscent of accelerated aging and an increased incidence of sarcomas and other tumors of mesenchymal origin."1.31Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. ( Emond, MJ; Gollahon, KA; Poot, M; Rabinovitch, PS; Silber, JR, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poot, M1
Gollahon, KA1
Emond, MJ1
Silber, JR1
Rabinovitch, PS1

Other Studies

1 other study available for methoxsalen and Adult Premature Aging Syndrome

ArticleYear
Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:7

    Topics: 4-Nitroquinoline-1-oxide; Apoptosis; Carcinogens; Cell Division; Cell Line; Cell Survival; Cells, Cu

2002