methoxsalen has been researched along with Adenocarcinoma in 1 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This trial explores SM-88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) METHODS: Forty-nine patients were randomized to daily 460 or 920 mg oral SM-88 with MPS (SM-88 Regimen)." | 5.51 | A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond. ( Chung, V; Hartley, ML; Kim, DW; Kim, S; Noel, MS; Ocean, AJ; Philip, PA; Picozzi, VJ; Staszewski, H; Van Tornout, JM; Wang-Gillam, A; Wong, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noel, MS | 1 |
| Kim, S | 1 |
| Hartley, ML | 1 |
| Wong, S | 1 |
| Picozzi, VJ | 1 |
| Staszewski, H | 1 |
| Kim, DW | 1 |
| Van Tornout, JM | 1 |
| Philip, PA | 1 |
| Chung, V | 1 |
| Ocean, AJ | 1 |
| Wang-Gillam, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Phase 2/3 Multi-Center Study of SM-88 in Subjects With Pancreatic Cancer Whose Disease Has Progressed or Recurred[NCT03512756] | Phase 2/Phase 3 | 132 participants (Actual) | Interventional | 2018-03-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methoxsalen and Adenocarcinoma
| Article | Year |
|---|---|
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neop | 2022 |