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methoxsalen and Acquired Immunodeficiency Syndrome

methoxsalen has been researched along with Acquired Immunodeficiency Syndrome in 1 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"Four consecutive AIDS patients with psoriasis and CD4 count lower than 20/mm3 were treated with 8-methoxypsoralen and UVA (PUVA)."1.30Impact of PUVA therapy on HIV viremia: a pilot study. ( Krischer, J; Lemonnier, E; Pechère, M; Perrin, L; Saurat, JH; Yerly, S, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pechère, M1
Yerly, S1
Lemonnier, E1
Krischer, J1
Perrin, L1
Saurat, JH1

Other Studies

1 other study available for methoxsalen and Acquired Immunodeficiency Syndrome

ArticleYear
Impact of PUVA therapy on HIV viremia: a pilot study.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; HIV-1; Humans; Methoxsale

1997