methoxamine has been researched along with Torsade de Pointes in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beekman, JD; Tieland, RG; Van Der Heyden, MA; Varkevisser, R; Vos, MA | 1 |
| Carlsson, L | 2 |
| Beekman, JD; de Boer, TP; Duker, G; Houtman, MJ; Jonsson, MK; Nalos, L; Peschar, M; Rook, MB; Sartipy, P; Thomsen, MB; van der Heyden, MA; van der Nagel, R; van Veen, TA; Varkevisser, R; Vos, MA | 1 |
| Acsai, K; Csanády, M; Dézsi, L; Farkas, A; Farkas, AS; Forster, T; Orosz, S; Papp, JG; Tóth, A; Varró, A | 1 |
| Hasumi, H; Hata, Y; Kaneko, N; Matsuda, R; Shimamoto, K | 1 |
| Dai, DZ; Dai, Y; Huang, ZJ; Ji, M; Li, N; Na, T | 1 |
| Belardinelli, L; Dhalla, AK; Robertson, C; Wang, WQ | 1 |
| Ajiki, K; Hayami, N; Inaba, H; Kunishima, T; Murakawa, Y; Sugishita, Y; Yamagishi, N; Yamagishi, S | 1 |
| Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G | 1 |
| Kamiya, T; Kawade, M; Ohe, T | 1 |
| Abrahamsson, C; Andersson, B; Carlsson, L; Duker, G; Schiller-Linhardt, G | 1 |
| Carlsson, L; Hallman, K | 1 |
| D'Alonzo, AJ; Darbenzio, RB; Zhu, JL | 1 |
| Chow, MS; Kluger, J; White, CM; Xie, J | 1 |
| Hou, CJ; Sung, RJ; Tan, HL | 1 |
| Anderson, ME; Mazur, A; Roden, DM | 1 |
| De Clerck, F; Lu, HR; Remeysen, P | 1 |
| Leunissen, JD; van Opstal, JM; Verduyn, SC; Vos, MA | 1 |
| Anderson, ME; Gbadebo, TD; Khoo, MS; Roden, DM; Temple, J; Trimble, RW | 1 |
| Chezalviel, F; Davy, JM; Ertzbischoff, O; Weissenburger, J | 1 |
3 review(s) available for methoxamine and Torsade de Pointes
| Article | Year |
|---|---|
The anaesthetised methoxamine-sensitised rabbit model of torsades de pointes.
Topics: Adrenergic alpha-Agonists; Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Guidelines as Topic; Humans; Methoxamine; Rabbits; Torsades de Pointes; Toxicity Tests | 2008 |
In vitro and in vivo models for testing arrhythmogenesis in drugs.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Disease Models, Animal; Dogs; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Heart; Heart Block; Heart Ventricles; Long QT Syndrome; Methoxamine; Rabbits; Torsades de Pointes | 2006 |
Assessment of the pro-arrhythmic potential of anti-arrhythmic drugs: an experimental approach.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Heart Block; Humans; Methoxamine; Rabbits; Torsades de Pointes | 2001 |
18 other study(ies) available for methoxamine and Torsade de Pointes
| Article | Year |
|---|---|
AV-block and conduction slowing prevail over TdP arrhythmias in the methoxamine-sensitized pro-arrhythmic rabbit model.
Topics: Action Potentials; Anesthetics; Animals; Anti-Arrhythmia Agents; Atrioventricular Block; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Flunarizine; Heart Conduction System; Heart Rate; Methoxamine; Phenethylamines; Rabbits; Sulfonamides; Time Factors; Torsades de Pointes | 2015 |
Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aza Compounds; Cell Line; Disease Models, Animal; Dogs; Embryonic Stem Cells; Female; Fluoroquinolones; Heart; Heart Block; Humans; Methoxamine; Moxifloxacin; Myocytes, Cardiac; Phenethylamines; Piperidines; Potassium Channel Blockers; Pyridines; Quinolines; Rabbits; Sulfonamides; Torsades de Pointes; Ventricular Remodeling | 2012 |
Importance of extracardiac alpha1-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Electrocardiography; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Methoxamine; Phenethylamines; Rabbits; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sulfonamides; Torsades de Pointes | 2006 |
K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Electrocardiography; Heart Rate; Long QT Syndrome; Male; Methoxamine; Potassium Channel Blockers; Quaternary Ammonium Compounds; Rabbits; Sodium Channel Blockers; Thiazepines; Torsades de Pointes | 2007 |
Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits.
Topics: Algorithms; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Electrocardiography; Female; Guinea Pigs; Heart Rate; Long QT Syndrome; Male; Membrane Potentials; Methoxamine; Molecular Structure; Myocardial Contraction; Myocytes, Cardiac; Naphthalenes; Phenethylamines; Potassium Channels, Inwardly Rectifying; Rabbits; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sulfonamides; Torsades de Pointes | 2007 |
Antitorsadogenic effects of ({+/-})-N-(2,6-dimethyl-phenyl)-(4[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine (ranolazine) in anesthetized rabbits.
Topics: Acetanilides; Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Female; Heart Rate; Lidocaine; Methoxamine; Phenylephrine; Piperazines; Potassium Channel Blockers; Prazosin; Quaternary Ammonium Compounds; Rabbits; Ranolazine; Torsades de Pointes | 2008 |
Human atrial natriuretic peptide suppresses torsades de pointes in rabbits.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Calcium Channels, L-Type; Cyclic GMP; Disease Models, Animal; Electrocardiography; Humans; Hydralazine; Male; Methoxamine; Pyrimidinones; Rabbits; Sympathomimetics; Torsades de Pointes; Vasodilator Agents | 2008 |
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes | 1993 |
Provocative testing and drug response in a patient with the long QT syndrome.
Topics: Adolescent; Drug Therapy, Combination; Electrocardiography; Epinephrine; Female; Humans; Isoproterenol; Long QT Syndrome; Methoxamine; Propranolol; Torsades de Pointes; Verapamil | 1995 |
Proarrhythmic effects of the class III agent almokalant: importance of infusion rate, QT dispersion, and early afterdepolarisations.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cats; Drug Administration Schedule; Electrophysiology; Heart; Infusions, Intravenous; Long QT Syndrome; Male; Methoxamine; Propanolamines; Purkinje Fibers; Rabbits; Torsades de Pointes | 1993 |
Prevention of class III-induced proarrhythmias by flecainide in an animal model of the acquired long QT syndrome.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Flecainide; Male; Methoxamine; Propanolamines; Rabbits; Torsades de Pointes | 1995 |
Effects of class III antiarrhythmic agents in an in vitro rabbit model of spontaneous torsades de pointe.
Topics: Acetylcholine; Action Potentials; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Heart; Heart Rate; In Vitro Techniques; Male; Methoxamine; Nadolol; Perfusion; Phenethylamines; Rabbits; Sulfonamides; Torsades de Pointes; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Prophylactic magnesium to decrease the arrhythmogenic potential of class III antiarrhythmic agents in a rabbit model.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Magnesium; Methoxamine; Quaternary Ammonium Compounds; Rabbits; Sympathomimetics; Torsades de Pointes | 1999 |
Effects of adenosine A1-receptor activation on torsade de pointes in rabbits.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Drug Interactions; Electrocardiography; Methoxamine; Neuroprotective Agents; Potassium Channels; Propranolol; Quaternary Ammonium Compounds; Rabbits; Torsades de Pointes | 1999 |
Systemic administration of calmodulin antagonist W-7 or protein kinase A inhibitor H-8 prevents torsade de pointes in rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Agonists; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Heart Rate; Isoquinolines; Long QT Syndrome; Male; Methoxamine; Quaternary Ammonium Compounds; Rabbits; Sulfonamides; Torsades de Pointes | 1999 |
Nonselective I(Kr)-blockers do not induce torsades de pointes in the anesthetized rabbit during alpha1-adrenoceptor stimulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Delayed Rectifier Potassium Channels; Electrocardiography; Heart Rate; Male; Methoxamine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Rabbits; Terfenadine; Torsades de Pointes | 2000 |
Calmodulin inhibitor W-7 unmasks a novel electrocardiographic parameter that predicts initiation of torsade de pointes.
Topics: Animals; Arrhythmias, Cardiac; Calmodulin; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; Heart Rate; Male; Methoxamine; Potassium Channel Blockers; Predictive Value of Tests; Quaternary Ammonium Compounds; Rabbits; Signal Processing, Computer-Assisted; Sulfonamides; Torsades de Pointes | 2002 |
[Experimental models of torsades de pointes].
Topics: Animals; Cesium; Dogs; Electrocardiography; Heart Conduction System; Hypokalemia; Methoxamine; Models, Biological; Rabbits; Torsades de Pointes | 1992 |