Page last updated: 2024-08-17

methoxamine and Hypertension, Portal

methoxamine has been researched along with Hypertension, Portal in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's12 (52.17)18.2507
2000's7 (30.43)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moeller, M; Pohl, S; Ripoll, C; Thonig, A; Zipprich, A1
Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Tsai, TH; Yang, YY1
Casteleyn, C; D'Hondt, M; De Winter, B; Francque, S; Kwanten, W; Laleman, W; Michielsen, P; Pelckmans, P; Ramon, A; Van Dyck, C; Van Marck, E; Van Marck, V; Van Steenkiste, C; Verbeke, L; Vermeulen, W1
Ai, JH; Qiu, FZ; Yang, Z; Zhu, T1
Cadelina, GW; Groszmann, RJ; Iwakiri, Y; Loureiro-Silva, MR1
Ai, JH; Qiu, FZ; Yang, Z1
Biecker, E; Heller, J; Hennenberg, M; Jochem, K; Leifeld, L; Sauerbruch, T; Trebicka, J; Zhou, Q1
Heinemann, A; Stauber, RE2
Atucha, NM; García-Estañ, J; Martínez, C; Ortíz, MC; Quesada, T1
Atucha, NM; García-Estañ, J; Groszmann, RJ1
Atucha, NM; García-Cardeña, G; Groszmann, RJ; Sessa, WE; Shah, V1
Cahill, PA; Hou, MC; Redmond, EM; Sitzmann, JV; Zhang, S1
Fickert, P; Heinemann, A; Holzer, P; Stauber, RE; Wachter, CH1
Atucha, NM; Fortepiani, LA; García-Estañ, J; Martínez, C; Ortíz, MC; Ruiz, FM1
Groszmann, RJ; Sessa, WC; Shah, V; Wiest, R1
Cadelina, G; Garcia-Cardena, G; Groszmann, RJ; Sessa, WC; Shah, V; Wiest, R1
Groszmann, RJ; Tsai, MH; Wiest, R1
Bonkovsky, HL; Fernandez, M; Lambrecht, RW1
Fulton, D; Gratton, JP; Groszmann, RJ; Iwakiri, Y; McCabe, TJ; Sessa, WC; Tsai, MH1
Albillos, A; Colombato, LA; Groszmann, RJ; Lee, FY1
Groszmann, RJ; Sieber, CC1
Bosch, J; Bruix, J; Kravetz, D; Mastai, R; Navasa, M; Rodés, J; Viola, C1

Other Studies

23 other study(ies) available for methoxamine and Hypertension, Portal

ArticleYear
Hepatic arterial vasodilation is independent of portal hypertension in early stages of cirrhosis.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Blotting, Western; Dose-Response Relationship, Drug; Hepatic Artery; Hypertension, Portal; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Liver Cirrhosis; Male; Methoxamine; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Rats, Wistar; Vascular Resistance; Vasodilation

2015
Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis.
    Clinical science (London, England : 1979), 2012, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animals; Arachidonic Acid; Benzofurans; Choline; Clodronic Acid; Diet, High-Fat; DNA Primers; Fatty Acids, Unsaturated; Fatty Liver; Gadolinium; Hemodynamics; Hypertension, Portal; Insulin Resistance; Kupffer Cells; Leptin; Methionine; Methoxamine; Microcirculation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Receptors, Thromboxane A2, Prostaglandin H2; RNA, Messenger; Sulfonylurea Compounds; Thiobarbituric Acid Reactive Substances; Thromboxane A2

2012
Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:10

    Topics: Analysis of Variance; Animals; Cytokines; Endothelin-1; Endothelium, Vascular; Fatty Liver; Hypertension, Portal; Liver; Liver Circulation; Liver Cirrhosis; Male; Methoxamine; Microscopy, Electron, Scanning; Microvessels; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents

2012
Heat shock protein 90 is responsible for hyperdynamic circulation in portal hypertensive rats.
    World journal of gastroenterology, 2003, Volume: 9, Issue:11

    Topics: Acetylcholine; Animals; Gene Expression; HSP90 Heat-Shock Proteins; Hypertension, Portal; Male; Methoxamine; Nitroprusside; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2003
A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats.
    Journal of hepatology, 2003, Volume: 39, Issue:6

    Topics: Animals; Drug Interactions; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Mesenteric Artery, Superior; Methoxamine; Nitrates; Nitric Oxide Donors; Portal Vein; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid; Vascular Resistance; Vasoconstrictor Agents

2003
[Role of heat shock protein 90 in hyperdynamic circulation of portal hypertensive rats].
    Zhonghua yi xue za zhi, 2004, Jan-02, Volume: 84, Issue:1

    Topics: Acetylcholine; Animals; Antibiotics, Antineoplastic; Benzoquinones; Blotting, Western; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Hypertension, Portal; Lactams, Macrocyclic; Male; Methoxamine; Portal Vein; Quinones; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents

2004
Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis.
    Gut, 2006, Volume: 55, Issue:9

    Topics: Animals; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Portal; Intracellular Signaling Peptides and Proteins; Liver; Liver Circulation; Liver Cirrhosis, Biliary; Male; Methoxamine; Microfilament Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Up-Regulation; Vascular Resistance; Vasoconstrictor Agents

2006
The role of inducible nitric oxide synthase in vascular hyporeactivity of endotoxin-treated and portal hypertensive rats.
    European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Endotoxins; Enzyme Induction; Escherichia coli; Guanidines; Hypertension, Portal; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vascular Resistance

1995
Role of protein kinase C in mesenteric pressor responses of rats with portal hypertension.
    British journal of pharmacology, 1996, Volume: 118, Issue:2

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Enzyme Activation; Hypertension, Portal; Male; Methoxamine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Splanchnic Circulation

1996
Effect of terlipressin on in vitro vascular hyporeactivity of portal hypertensive rats.
    Journal of hepatology, 1996, Volume: 24, Issue:6

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Portal; In Vitro Techniques; Lypressin; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Terlipressin; Vasodilation

1996
Renal response to methoxamine in portal hypertensive rats: role of prostaglandins and nitric oxide.
    Journal of hepatology, 1996, Volume: 25, Issue:2

    Topics: Acetylcholine; Animals; Enzyme Inhibitors; Hypertension, Portal; In Vitro Techniques; Indomethacin; Kidney; Male; Methoxamine; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Prostaglandins; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction; Vasodilator Agents

1996
Role of endothelium in the abnormal response of mesenteric vessels in rats with portal hypertension and liver cirrhosis.
    Gastroenterology, 1996, Volume: 111, Issue:6

    Topics: Animals; Endothelium, Vascular; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Methoxamine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstriction; Vasoconstrictor Agents

1996
Enhanced G-protein-induced relaxation in portal hypertensive rats: role of nitric oxide.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:1

    Topics: Animals; Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Hemodynamics; Hypertension, Portal; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Fluoride

1997
Nitric oxide-dependent and -independent vascular hyporeactivity in mesenteric arteries of portal hypertensive rats.
    British journal of pharmacology, 1997, Volume: 121, Issue:5

    Topics: Animals; Arginine Vasopressin; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents

1997
Role of cyclic guanosine monophosphate and K+ channels as mediators of the mesenteric vascular hyporesponsiveness in portal hypertensive rats.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:4

    Topics: Animals; Cyclic GMP; Hypertension, Portal; Male; Mesenteric Arteries; Methoxamine; Nitric Oxide; Potassium Channels; Rats; Rats, Sprague-Dawley; Tetraethylammonium Compounds

1998
NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Endothelium, Vascular; Hypertension, Portal; Kinetics; Luminescent Measurements; Male; Mesenteric Artery, Superior; Methoxamine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Stress, Mechanical

1999
Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension.
    The American journal of physiology, 1999, Volume: 277, Issue:2

    Topics: Acetylcholine; Animals; Benzoquinones; Blood Vessels; HSP90 Heat-Shock Proteins; Hypertension, Portal; In Vitro Techniques; Lactams, Macrocyclic; Male; Methoxamine; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Quinones; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Tissue Distribution; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1999
Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats.
    Gastroenterology, 2001, Volume: 120, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Endothelium, Vascular; Hypertension, Portal; Male; Methoxamine; Nitric Oxide; Octreotide; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstrictor Agents

2001
Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity.
    Journal of hepatology, 2001, Volume: 34, Issue:6

    Topics: Animals; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hypertension, Portal; Male; Metalloporphyrins; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstriction

2001
Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Androstadienes; Animals; Enzyme Inhibitors; Hypertension, Portal; Ligation; Male; Mesenteric Artery, Superior; Methoxamine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphorylation; Portal Vein; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Wortmannin

2002
The role of nitric oxide in the vascular hyporesponsiveness to methoxamine in portal hypertensive rats.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:4

    Topics: Animals; Arginine; Blood Pressure; Blood Vessels; Dose-Response Relationship, Drug; Hypertension, Portal; Male; Methoxamine; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Vascular Resistance

1992
In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 1

    Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Hypertension, Portal; Kinetics; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Rats; Rats, Inbred Strains

1992
Effects of alpha-adrenergic stimulation and beta-adrenergic blockade on azygos blood flow and splanchnic haemodynamics in patients with cirrhosis.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Azygos Vein; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Methoxamine; Middle Aged; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Splanchnic Circulation

1987