Page last updated: 2024-08-25

methotrexate and Weight Loss

methotrexate has been researched along with Weight Loss in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's10 (27.78)18.2507
2000's9 (25.00)29.6817
2010's11 (30.56)24.3611
2020's4 (11.11)2.80

Authors

AuthorsStudies
Chen, L; Fang, Q; Huang, X; Ouyang, D; Rao, T; Tan, Z; Zeng, X; Zhou, L1
da Silva Ferreira, AR; Harmsen, HJM; Havinga, R; Lichtenberg Cloo, S; Tissing, WJE; Vermeij, WP; Wardill, HR1
Haberstroh, WD; Lenka, A; Triano, MJ; Whelton, SA1
Aslan, K; Azizoglu, ZB; Deniz, K; Erdem, S; Haliloglu, Y; Karakukcu, M; Patiroglu, T; Per, S; Suna, PA; Tasdemir, A; Unal, E; Yay, AH; Yilmaz, E1
Epafra, E; Janabi, M; Kazahura, P; Lyimo, F; Nicholaus, P; Pallangyo, P1
Adelowo, O; Anaba, EL; Ekeigwe, NL; Olaosebikan, H1
Oberhofer, E1
Abraham, P; Isaac, B; Kolli, VK; Natarajan, K; Selvakumar, D1
Baker, JF; Cannon, GW; Caplan, L; Haroldsen, C; Ibrahim, S; Mikuls, TR1
Araújo, TE; Borba, PB; da Silva, AI; de Araújo Júnior, RF; de Araújo, AA; de Souza, FH; Nogueira, AC; Saldanha, TS1
Bayat, N; Bükücü, N; Sencar, L; Tarakçioğlu, M; Yüncü, M1
Gao, HF; Li, LF; Liu, ZH; Shen, T; Shi, CJ; Wen, XS; Xian, CJ; Xu, XK1
Bauerova, K; Jurcovicova, J; Rovensky, J; Scsukova, S; Stancikova, M; Svik, K1
Hawks, RG; Meza, JL; Post-White, JE; Sacks, N; Seibel, NL; Smith, LM; Withycombe, JS1
El-Haddad, B; Hammoud, D; Shahouri, S; Shaver, T1
Del Giglio, M; Girolomoni, G; Gisondi, P; Tessari, G1
Ameloot, K; De Wever, W; Goffin, K; Palmers, PJ; Voigt, JU1
Bertino, JR; Chabner, BA; Johns, DG1
Balthasar, JP; Lobo, ED1
Balthasar, JP; Lobo, ED; Soda, DM1
Araujo, DH; Brito, GA; Carneiro-Filho, BA; Carvalho, GH; Cavalcante, MC; Lima, AA; Lima, IP; Lima, V; Monteiro, SM; Ribeiro, RA; Santos, FN1
Chau, Y; Dang, NM; Langer, R; Padera, RF1
Celik, A; Eralp, A; Yüncü, M1
Arakawa, Y; Hirotani, Y; Ikeda, K; Kitamura, K; Kurokawa, N; Li, J; Tanaka, K; Yamamoto, K1
Baracos, VE; Cynober, L; Gugins, S; Le Bricon, T1
Chevreau, N; Funk-Archuleta, M1
Catsoulakos, P; Karakiulakis, G; Pispirigos, K1
Black, KW; Prielipp, R; Roberts, P; Zaloga, GP1
Kadin, ME; Sajjadian, A; Vonderheid, EC1
Gilchrist, GS; O'Marcaigh, AS1
Higuchi, S; Inoue, K; Nakano, S; Ogawa, N; Ohdo, S; Yukawa, E1
Akman, RY; Arikan, AY; Can, C; Senel, FM1
Frerichs, J; Hoijer, M; Jager, D; Koetsier, M; M'Rabet, L; Meijer, HP; Smeets, RL; van't Land, B1
Eagan, RT; Feldman, ER; Schaid, DJ1
Bortnowski, HB; Rosenthal, RC1
Allum, WH; Hallissey, MT; Kelly, KA1

Trials

2 trial(s) available for methotrexate and Weight Loss

ArticleYear
Weight reduction alone may not be sufficient to maintain disease remission in obese patients with psoriasis: a randomized, investigator-blinded study.
    Dermatology (Basel, Switzerland), 2012, Volume: 224, Issue:1

    Topics: Adult; Aged; Body Mass Index; Dermatologic Agents; Diet, Reducing; Female; Humans; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Treatment Outcome; Weight Loss

2012
Adjuvant chemotherapy in operable gastric cancer. 5 year follow-up of first British Stomach Cancer Group trial.
    Lancet (London, England), 1989, Mar-18, Volume: 1, Issue:8638

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; England; Female; Fluorouracil; Follow-Up Studies; Gastrectomy; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Multicenter Studies as Topic; Neoplasm Staging; Prognosis; Random Allocation; Stomach Neoplasms; Vincristine; Wales; Weight Loss

1989

Other Studies

34 other study(ies) available for methotrexate and Weight Loss

ArticleYear
Leucovorin ameliorated methotrexate induced intestinal toxicity via modulation of the gut microbiota.
    Toxicology and applied pharmacology, 2020, 03-15, Volume: 391

    Topics: Animals; Bifidobacterium; Colon; DNA, Bacterial; Gastrointestinal Microbiome; Intestinal Diseases; Leucovorin; Male; Methotrexate; Mice; Mice, Inbred BALB C; RNA, Ribosomal, 16S; Weight Loss

2020
Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis.
    Gut microbes, 2020, 11-09, Volume: 12, Issue:1

    Topics: Animals; Bacteria; Cell Proliferation; Citrulline; Enterocytes; Fasting; Feces; Gastrointestinal Microbiome; Gastrointestinal Tract; Intestinal Mucosa; Jejunum; Lactobacillus; Male; Methotrexate; Mucositis; Rats; Rats, Wistar; Weight Loss

2020
Relapsed granulomatosis with polyangiitis with panhypopituitarism.
    BMJ case reports, 2021, Jan-28, Volume: 14, Issue:1

    Topics: Adrenal Insufficiency; Androgens; Diabetes Insipidus; Fatigue; Glucocorticoids; Granulomatosis with Polyangiitis; Hormone Replacement Therapy; Humans; Hypogonadism; Hypopituitarism; Hypothyroidism; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Pituitary Diseases; Pituitary Gland; Recurrence; Rhinitis; Sella Turcica; Sinusitis; Testosterone; Thyroxine; Weight Loss

2021
Therapeutic effects of vitamin D and IL-22 on methotrexate-induced mucositis in mice.
    Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Gene Transfer Techniques; Inflammation Mediators; Interleukin-22; Interleukins; Intestinal Mucosa; Methotrexate; Mice; Mice, Inbred BALB C; Mucositis; Vitamin D; Weight Loss

2022
Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report.
    Journal of medical case reports, 2017, Jun-10, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Blindness; Computed Tomography Angiography; Dexamethasone; Female; Humans; Methotrexate; Optic Neuropathy, Ischemic; Quality of Life; Takayasu Arteritis; Treatment Outcome; Weight Loss; Young Adult

2017
Eosinophilic granulomatosis with polyangiitis in a Nigerian woman.
    BMJ case reports, 2019, Jun-18, Volume: 12, Issue:6

    Topics: Antibodies, Antineutrophil Cytoplasmic; Edema; Female; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Leg Ulcer; Methotrexate; Middle Aged; Nigeria; Treatment Outcome; Weight Loss

2019
[Weight loss as the alpha and omega. New EULAR recommendations for hip and knee arthrosis].
    MMW Fortschritte der Medizin, 2013, Aug-22, Volume: 155, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Combined Modality Therapy; Exercise; Feeding Behavior; Humans; Methotrexate; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Education as Topic; Shoes; Weight Loss

2013
Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis.
    Human & experimental toxicology, 2014, Volume: 33, Issue:10

    Topics: Animals; Cell Survival; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Enteritis; Enterocytes; Intestine, Small; Male; Methotrexate; Mitochondria; Mitochondrial Diseases; Peroxynitrous Acid; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Weight Loss

2014
Predictors of longterm changes in body mass index in rheumatoid arthritis.
    The Journal of rheumatology, 2015, Volume: 42, Issue:6

    Topics: Adult; Age Factors; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Hospitals, Veterans; Humans; Linear Models; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prednisone; Registries; Risk Assessment; Sex Factors; Time Factors; Treatment Outcome; United States; Weight Loss

2015
In a methotrexate-induced model of intestinal mucositis, olmesartan reduced inflammation and induced enteropathy characterized by severe diarrhea, weight loss, and reduced sucrose activity.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Diarrhea; Disease Models, Animal; Imidazoles; Inflammation; Interleukin-1beta; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Mucositis; Neoplasms; Olmesartan Medoxomil; Rats, Wistar; Sucrose; Tetrazoles; Tumor Necrosis Factor-alpha; Weight Loss

2015
The effect of vitamin E and L-carnitine against methotrexate-induced injury in rat testis.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:3

    Topics: Analysis of Variance; Animals; Antioxidants; Carnitine; Male; Malondialdehyde; Methotrexate; Rats; Rats, Wistar; Superoxide Dismutase; Testicular Diseases; Vitamin B Complex; Vitamin E; Weight Loss

2015
Steamed root of Rehmannia glutinosa Libosch (Plantaginaceae) alleviates methotrexate-induced intestinal mucositis in rats.
    Journal of ethnopharmacology, 2016, May-13, Volume: 183

    Topics: Animals; Disease Models, Animal; Female; Glutathione; Intestinal Mucosa; Methotrexate; Mucositis; Plant Preparations; Plant Roots; Plantaginaceae; Rats; Rats, Wistar; Rehmannia; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Weight Loss

2016
Methotrexate treatment ameliorated testicular suppression and anorexia related leptin reduction in rats with adjuvant arthritis.
    Rheumatology international, 2009, Volume: 29, Issue:10

    Topics: Animals; Anorexia; Arthritis, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Leptin; Male; Methotrexate; Rats; Rats, Inbred Lew; Serum Albumin; Testis; Testosterone; Weight Loss

2009
Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Mass Index; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Daunorubicin; Ethnicity; Female; Gastrointestinal Diseases; Glucose Intolerance; Humans; Incidence; Male; Methotrexate; Obesity; Pancreatitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Vincristine; Weight Gain; Weight Loss; Young Adult

2009
Malignancy-associated multicentric reticulohistiocytosis.
    Rheumatology international, 2011, Volume: 31, Issue:9

    Topics: Antihypertensive Agents; Antineoplastic Agents; Arthralgia; Atenolol; Combined Modality Therapy; Drug Therapy, Combination; Fatigue; Female; Hand; Histiocytosis, Non-Langerhans-Cell; Humans; Hydrochlorothiazide; Hypertension; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasms, Squamous Cell; Prednisone; Radiography; Weight Loss

2011
An echocardiographic finding leading to the diagnosis of giant cell arteritis.
    European heart journal. Cardiovascular Imaging, 2013, Volume: 14, Issue:5

    Topics: Aged; Echocardiography, Transesophageal; Fatigue; Follow-Up Studies; Giant Cell Arteritis; Humans; Methotrexate; Methylprednisolone; Positron-Emission Tomography; Risk Assessment; Syncope; Treatment Outcome; Weight Loss

2013
Enzymatic cleavage of methotrexate provides a method for prevention of drug toxicity.
    Nature, 1972, Oct-13, Volume: 239, Issue:5372

    Topics: Animals; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; gamma-Glutamyl Hydrolase; Half-Life; Hydrolysis; Leucovorin; Leukemia; Male; Methotrexate; Mice; Pseudomonas; Survival Rate; Time Factors; Weight Loss

1972
Pharmacokinetic-pharmacodynamic modeling of methotrexate-induced toxicity in mice.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:8

    Topics: Animals; Male; Methotrexate; Mice; Models, Chemical; Weight Loss

2003
Application of pharmacokinetic-pharmacodynamic modeling to predict the kinetic and dynamic effects of anti-methotrexate antibodies in mice.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Computer Simulation; Hybridomas; Male; Methotrexate; Mice; Models, Biological; Models, Chemical; Predictive Value of Tests; Weight Loss

2003
Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenum; Eating; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methotrexate; Potassium; Rats; Rats, Wistar; Sodium; Stomatitis; Water; Weight Loss

2004
Antitumor efficacy of a novel polymer-peptide-drug conjugate in human tumor xenograft models.
    International journal of cancer, 2006, Mar-15, Volume: 118, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbohydrate Sequence; Cell Line, Tumor; Dextrans; Drug Design; Female; Humans; Immunohistochemistry; Intestine, Small; Ki-67 Antigen; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methotrexate; Mice; Mice, SCID; Molecular Sequence Data; Molecular Structure; Neoplasms; Peptides; Treatment Outcome; Weight Loss; Xenograft Model Antitumor Assays

2006
Effect of aged garlic extract against methotrexate-induced damage to the small intestine in rats.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:6

    Topics: Animals; Diarrhea; Garlic; Intestine, Small; Lactic Acid; Male; Malondialdehyde; Methotrexate; Plant Extracts; Rats; Rats, Wistar; Weight Loss

2006
Correlation between plasma glucagon-like peptide 2 levels and proliferative makers in small intestinal injury in rats induced by methotrexate administration.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:11

    Topics: Administration, Oral; Animals; Biomarkers; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucagon-Like Peptide 2; Intestinal Mucosa; Intestine, Small; Membrane Proteins; Methotrexate; Mucositis; Rats; Weight Loss

2006
Negative impact of cancer chemotherapy on protein metabolism in healthy and tumor-bearing rats.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:10

    Topics: Animals; Antineoplastic Agents; Cachexia; Cisplatin; Cyclophosphamide; DNA; Eating; Female; Fluorouracil; Intestine, Small; Liver; Liver Neoplasms, Experimental; Methotrexate; Muscle, Skeletal; Nitrogen; Organ Size; Proteins; Rats; Rats, Sprague-Dawley; RNA; Weight Loss

1995
Effect of enteral formulas on methotrexate toxicity.
    Nutrition and cancer, 1995, Volume: 23, Issue:2

    Topics: Animals; Caseins; Diarrhea; Dietary Fiber; Enteral Nutrition; Food, Formulated; Humans; Male; Methotrexate; Plant Proteins, Dietary; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weight Loss

1995
Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Azasteroids; Blood Glucose; Chemical and Drug Induced Liver Injury; Chlorambucil; Cholesterol; Cisplatin; Epirubicin; gamma-Glutamyltransferase; Kidney; Kidney Diseases; Liver Diseases; Male; Methotrexate; Nitrogen; Nitrogen Mustard Compounds; Potassium; Rats; Rats, Wistar; Sodium; Weight Loss

1993
Gut bacterial translocation/dissemination explains the increased mortality produced by parenteral nutrition following methotrexate.
    Circulatory shock, 1993, Volume: 39, Issue:4

    Topics: Animals; Colony Count, Microbial; Digestive System; Enteral Nutrition; Intestinal Mucosa; Male; Methotrexate; Organ Size; Parenteral Nutrition, Total; Proteins; Rats; Rats, Sprague-Dawley; Weight Loss

1993
Methotrexate is effective therapy for lymphomatoid papulosis and other primary cutaneous CD30-positive lymphoproliferative disorders.
    Journal of the American Academy of Dermatology, 1996, Volume: 34, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anemia; Antimetabolites, Antineoplastic; Aspartate Aminotransferases; Dermatologic Agents; Diarrhea; Drug Administration Schedule; Fatigue; Female; Follow-Up Studies; Humans; Ki-1 Antigen; Liver Cirrhosis; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Lymphomatoid Papulosis; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Nausea; Remission Induction; Skin Diseases; Skin Neoplasms; Weight Loss

1996
Dose reduction of chemotherapeutic agents after weight loss.
    American journal of clinical oncology, 1997, Volume: 20, Issue:2

    Topics: Antineoplastic Agents; Body Surface Area; Computer Simulation; Drug Therapy, Computer-Assisted; Humans; Methotrexate; Models, Biological; Weight Loss

1997
Chronotoxicity of methotrexate in mice and its relation to circadian rhythm of DNA synthesis and pharmacokinetics.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Circadian Rhythm; DNA; Folic Acid; Leukocyte Count; Male; Methotrexate; Mice; Mice, Inbred ICR; Weight Loss

1997
Comparison of the effects of various anticancer agents on intestinal anastomosis after intraperitoneal administration.
    Surgery today, 1999, Volume: 29, Issue:8

    Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Doxorubicin; Fluorouracil; Injections, Intraperitoneal; Intestine, Small; Male; Methotrexate; Rats; Rats, Wistar; Statistics, Nonparametric; Weight Loss; Wound Healing

1999
Transforming Growth Factor-beta2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling.
    British journal of cancer, 2002, Jul-01, Volume: 87, Issue:1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Atrophy; Cell Cycle; Cell Death; Disease Models, Animal; Epithelial Cells; Female; Immunosuppressive Agents; Intestine, Small; Methotrexate; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta2; Weight Loss

2002
Metastatic bronchioloalveolar carcinoma and metastatic adenocarcinoma of the lung: comparison of clinical manifestations, chemotherapeutic responses, and prognosis.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Lomustine; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Methotrexate; Middle Aged; Mitomycin; Pleural Neoplasms; Prednisone; Prognosis; Remission Induction; Risk Factors; Sex Factors; Survival Rate; Triazines; Vincristine; Weight Loss

1992
Preclinical evaluation of L-asparaginase and methotrexate administered at intermediate doses in dogs.
    American journal of veterinary research, 1991, Volume: 52, Issue:10

    Topics: Animals; Asparaginase; Diarrhea; Dog Diseases; Dogs; Female; Male; Methotrexate; Random Allocation; Vomiting; Weight Loss

1991