methotrexate has been researched along with Thrombopenia in 176 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (47.16) | 18.7374 |
| 1990's | 36 (20.45) | 18.2507 |
| 2000's | 29 (16.48) | 29.6817 |
| 2010's | 20 (11.36) | 24.3611 |
| 2020's | 8 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Alakel, N; Balaian, E; Bornhäuser, M; Heuschkel, S; Knoth, H; Kretschmann, T; Kroschinsky, F; Quick, S; Richter, S; Röllig, C; Teipel, R; von Bonin, M; von Bonin, S | 1 |
| Badillo, M; Fayad, L; Feng, L; Flowers, CR; Fowler, N; Hagemeister, FB; Hill, HA; Iyer, SP; Jain, P; Jorgensen, J; Kanagal-Shamanna, R; Lee, HJ; Li, S; Lin, P; Medeiros, LJ; Nair, R; Nastoupil, L; Navsaria, L; Nogueras Gonzalez, GM; Ok, CY; Patel, KP; Samaniego, F; Santos, D; Steiner, R; Tang, G; Thirumurthi, S; Vega, F; Wagner-Bartak, N; Wang, L; Wang, ML; Wang, SA; Westin, JR; Xu, G; Xuelin, H; Yao, Y; Yin, CC; Zhao, S | 1 |
| Heller, T; Kleiner, DE; Lanis, A; Rider, LG; Shenoi, S; Vittal, A; Volochayev, R | 1 |
| Cruickshank, A; Koury, J | 1 |
| Lyu, H; Solomon, DH; Vanni, KMM | 1 |
| Li, J; Li, R; Lu, X; Zhang, B; Zhang, Y | 1 |
| Abhishek, A; Aithal, GP; Card, T; Doherty, M; Grainge, MJ; Mallen, CD; Nakafero, G; Taal, MW; Zhang, W | 1 |
| Aggarwal, A; Dhawan, V; Dhir, V; Gupta, R; Jain, S; Khullar, A; Leishangthem, B; Maurya, S; Naidu, S; Sharma, A; Sharma, SK | 1 |
| Cacciavillano, W; Rose, A; Scopinaro, M; Villegas Rubio, JA; Zubizarreta, P | 1 |
| Giagounidis, A; Haase, S; Mitsimponas, N; Mitsogianni, M | 1 |
| Althaus, K; Busemann, C; Friesecke, S; Greinacher, A; Hron, G; Knutson, F; Lubenow, N; Thiele, T | 1 |
| Barr, PM; Caimi, PF; Carson, KR; Evens, AM; Gordon, LI; Gregory, SA; Helenowski, I; Islam, N; Jovanovic, B; Kolesar, J; Nabhan, C | 1 |
| Bai, B; Cai, QC; Cai, QQ; Gao, Y; Huang, HQ; Jiang, WQ; Wang, XX; Xia, YF; Xia, ZJ | 1 |
| Brion, A; Chabin, M; Clavert, A; Colombat, P; Cumin, I; Delwail, V; Escoffre-Barbe, M; Gardembas, M; Ingrand, P; Lacotte-Thierry, L; Legouffe, E; Olivier, G; Solal-Celigny, P | 1 |
| Magliano, M; Mankia, KS; Tucker, LJ | 1 |
| Frandsen, T; Nersting, J; Rosthøj, S; Schmiegelow, K; Vang, SI | 1 |
| Lewis, H; Mahdi, AJ; Rowntree, C | 1 |
| Ambrosetti, A; Balzarotti, M; Binder, M; Cavalli, F; Cwynarski, K; Deckert, M; Fabbri, A; Ferrari, A; Ferreri, AJ; Finke, J; Fox, CP; Gørløv, JS; Hemmaway, C; Hertenstein, B; Hess, G; Illerhaus, G; Johnson, P; Keller, U; Krause, SW; Levis, A; Linton, KM; Panse, J; Pisani, F; Politi, LS; Ponzoni, M; Pukrop, T; Pulczynski, E; Reni, M; Rosée, PL; Roth, A; Rudà, R; Schmoll, HJ; Schorb, E; Stilgenbauer, S; Torri, V; Tucci, A; Zucca, E | 1 |
| Ahn, HK; Chang, MH; Kim, SJ; Kim, WS; Lee, SJ; Yi, JH | 1 |
| Schmiegelow, K; Schroeder, H; van Kooten Niekerk, PB | 1 |
| Deckert, M; Feuerhake, F; Finke, J; Ihorst, G; Illerhaus, G; Marks, R; Müller, F; Ostertag, C | 1 |
| Aksoylar, S; Cetingul, N; Cinar, M; Eroglu, Z; Gumus, S; Kantar, M; Kosova, B; Tetik, A; Topcuoglu, N; Toroslu, E; Zafer, N | 1 |
| Guan, ZZ; Lin, H; Ling, JY; Luo, WB; Peng, RJ; Sun, XF; Xia, Y; Xiang, XJ; Zhen, ZJ; Zheng, L | 1 |
| Bohanec Grabar, P; Dolžan, V; Faganel Kotnik, B; Grabnar, I; Jazbec, J | 1 |
| Cui, L; Gao, C; Li, WJ; Li, ZG; Liu, SG; Zhao, XX | 1 |
| Ahmed, M; Gilani, ST; Khan, DA; Khan, FA | 1 |
| Dutta, TK; Karyampudi, A; Krishnamurthy, A; Vishwanath, VK | 1 |
| Dasari, P; Sagili, H | 1 |
| Apibal, S; Hongeng, S; Koomdee, N; Pakakasama, S | 1 |
| Doi, A; Kurita, S; Morishima, K; Nagata, N; Nakanishi, M; Nakatani, K; Nishi, Y; Yagi, M; Yamama, Y | 1 |
| Hatta, Y; Hirabayashi, Y; Hojo, A; Horikoshi, A; Iriyama, N; Kiso, S; Kobayashi, S; Kobayashi, Y; Kodaira, H; Kura, Y; Kurita, D; Kusuda, M; Miura, K; Nakagawa, M; Sawada, U; Takahashi, H; Takeuchi, J; Uchino, Y; Yagi, M; Yamazaki, T | 1 |
| Abrams, K; Berkun, Y; Brik, R; Brunner, HI; Calvo, I; Cimaz, R; Constantin, T; Erguven, M; Ferrandiz, MA; Flato, B; Gamir, ML; Goffin, L; Grom, A; Hofer, M; Horneff, G; Kallinich, T; Kasapcopur, O; Kim, D; Kone-Paut, I; Lheritier, K; Lovell, DJ; Magnusson, B; Martini, A; McCann, L; Nistala, K; Oliveira, SK; Ozen, S; Quartier, P; Ruperto, N; Rutkowska-Sak, L; Schneider, R; Sztajnbok, F; Uziel, Y; Viola, S; Wouters, C; Wulffraat, N | 1 |
| Binard, A; Devauchelle-Pensec, V; Fautrel, B; Flipo, RM; Jousse-Joulin, S; Le Boëdec, M; Le Loët, X; Marhadour, T; Ménard, JF; Saraux, A | 1 |
| Arellano-Rodrigo, E; Bessell, EM; Graus, F; López-Guillermo, A; Montserrat, E; Nomdedeu, B | 1 |
| ALEXANDRE, GP; DAMMIN, GJ; MURRAY, JE; NOLAN, B | 1 |
| BEAHRS, OH; CALDAROLA, VT; HARRISON, EG | 1 |
| KEIDAN, SE; MAINWARING, D | 1 |
| Akaza, H; Hayashi, H; Hinotsu, S; Kawai, K; Miyanaga, N; Miyazaki, J; Onozawa, M; Shimazui, T; Tsukamoto, S | 1 |
| Aravantinos, G; Bafaloukos, D; Bamias, A; Bamias, C; Deliveliotis, C; Dimopoulos, MA; Gika, D; Kalofonos, C; Kosmidis, P; Kourousis, C; Koutras, A; Mitropoulos, D; Papadimitriou, C; Papakostas, P; Pectasides, D; Samantas, E; Xiros, N; Zervas, A | 1 |
| de Dios Luna, J; Hidalgo-Tenorio, C; Jiménez-Alonso, J; Martínez-Brocal, A; Sabio, JM; Tallada, M | 1 |
| Komatsu, H; Matsuzaki, M; Morikawa, H; Nakanishi, S; Nakano, M | 1 |
| Gou, HF; Hou, M; Li, L; Qiu, M; Yan, X; Zhu, J | 1 |
| Openshaw, H | 1 |
| Khanam, A; Mehreen, L | 1 |
| Calcino, LJ; Hill, RL; McEwen, J; Purcell, PM; Riley, CG | 1 |
| André, N; Bernard, JL; Boyer, M; Coze, C; Delorme, J; Gentet, JC; Rome, A | 1 |
| Amory, JK; Kalus, RM; Saint, S; Shojania, KG | 1 |
| Glantz, M; Przekop, AA; Przekop, PR; Tulgan, H | 1 |
| Hirobe, M; Honma, I; Itoh, N; Maeda, T; Masumori, N; Takahashi, A; Tsukamoto, T | 1 |
| Akutsu, M; Inoue, K; Izumi, T; Kano, Y; Katano, S; Kobayashi, H; Masuda, Y; Muroi, K; Nagashima, T; Ohmine, K; Ozawa, K; Shirai, T; Takagi, S; Tsunoda, S; Ueda, M; Ueda, T | 1 |
| Hayashi, Y; Kobayashi, R; Kondo, T; Kurata, T; Kutsuzawa, T; Shioya, S; Sonoda, Y; Takasaki, Y; Tamaya, S; Yamauchi, T | 1 |
| Brema, F; Campora, E; Porcile, G; Rosso, R; Santi, L; Stefani, G | 1 |
| Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Vogl, SE | 1 |
| Ahmed, T; Harper, HD; Kemeny, NE; Michaelson, RA; Yip, LC | 1 |
| Berkowitz, RS; Bernstein, MR; Goldstein, DP | 2 |
| Capizzi, RL; Carney, C; Delaney, D; Kahn, L; Kirsch, M; Lipper, S; Neijstrom, ES; Rudnick, SA | 1 |
| Batley, F; Chen, TY; Cohen, M; Kakos, G; Kilman, J; Mountain, CF; Sealy, R; Stanley, K; Tucker, RD; Vasko, J; Vincent, RG; Williams, TE; Wilson, HE | 1 |
| Baum, E; Bleyer, WA; Fryer, C; Griffin, T; Lampkin, B; Lukens, J; Morgan, E; Movassaghi, N; Provisor, A; White, H | 1 |
| Carpenter, J; Fishkin, E; Krauss, S; Moore, MR; Raab, S; Raney, M; Smalley, RV; Stagg, M; Velez-Garcia, E; Vogel, CL | 1 |
| Carey, RW; Cuttner, J; Ellison, RR; Gottlieb, AJ; Henderson, ES; Levy, RN; Rafla, S; Silver, RT; Terebelo, H; Weinberg, V | 1 |
| Beck, TM; Curtis, PW; Hart, NE; Smith, CE; Woodard, DA | 1 |
| Chahinian, AP; Green, G; Holland, JF | 1 |
| Blumenschein, GR; Buzdar, AU; Distefano, A; Pinnamaneni, K; Yap, HY | 1 |
| Jungi, WF; Senn, HJ; Waibel, PJ | 1 |
| Evans, WK; Gospodarowicz, M; Tannock, IF | 1 |
| Golomb, HM; Sweet, DL | 1 |
| Chabner, BA; Donehower, RC; Schilsky, RL | 1 |
| Demitrish, M; Duffin, H; Enochs, K; Groshko, G; Lockhard, C; Maniscalco-Greb, E; Vaughn, CB | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Rygård, J | 1 |
| Gropp, C; Havemann, K | 1 |
| Gibb, I; Hall, RR; Heath, AB; Herring, DW | 1 |
| Bron, D; Carde, P; de Bock, R; De Wolf-Peeters, C; Delmer, A; Keunig, JJ; Keuning, JJ; Somers, R; Thomas, J; Tirelli, U | 1 |
| Igawa, M; Kadena, H; Ueda, M; Usui, T | 1 |
| Armand, JP; Cappelaere, P; Clavel, M; Cognetti, F; de Graeff, A; de Mulder, PH; Schornagel, JH; Vermorken, JB; Verweij, J; Wildiers, J | 1 |
| Ballestrero, A; Basta, P; Brema, F; Ferrando, F; Ghio, R; Gobbi, M; Moraglio, L; Patrone, F; Sessarego, M; Valbonesi, M | 1 |
| Chessells, JM; Hirst, WJ; Layton, DM; Mieli-Vergani, G; Pritchard, J; Singh, S; Strobel, S | 1 |
| Brunner, V; Bugat, R; Canal, P; Chatelut, E; Chevreau, C; Houin, G; Martinez, M | 1 |
| Greco, FA; Hainsworth, JD; Johnson, DH; Lamar, RE; Murphy, PB | 1 |
| Aglietta, M; Carnino, F; Gavosto, F; Monzeglio, C; Pasquino, P; Stern, AC | 1 |
| Bonadonna, G; Brambilla, C; Ferrari, L; Passoni, P | 1 |
| Ashley, S; Holborn, J; Jones, AL; Smith, IE | 1 |
| Ashley, SE; Luckit, J; Montes, A; O'Brien, ME; Powles, TJ; Treleaven, J | 1 |
| Burghouts, JT; Conroy, T; de Graeff, A; Fickers, M; Lalisang, F; Paillot, B; Roelofs, EJ; Wagener, DJ; Wils, J | 1 |
| Adde, M; Arndt, C; Gootenberg, J; Horak, ID; Jaffe, E; Magrath, I; Neely, J; Nieder, M; Seibel, N; Shad, A; Venzon, D; Wittes, RA | 1 |
| Bander, JJ; Weinmann, M | 1 |
| Franck, H; Herborn, G; Rau, R | 2 |
| Carletti, S; Frondizi, D; Maira, G; Mastronardi, L; Spera, C | 1 |
| Barisone, E; Brach Del Prever, A; Leone, L; Miniero, R; Ridolfi, L; Vivalda, M; Vivenza, C | 1 |
| Baume, D; Bladou, F; Camerlo, J; Coulange, C; Cowen, D; Gravis, G; Lechevallier, E; Maraninchi, D; Resbeut, M; Serment, G; Viens, P | 1 |
| Cooley, TP; Dezube, BJ; Herndier, B; Huang, J; Kaplan, LD; Levine, AM; Northfelt, DW; Straus, DJ; Testa, MA; Tulpule, A; Von Roenn, J | 1 |
| Acquista, CA; Covelli, M; De Bari, C; Dell'Accio, F; Iannone, F; Lapadula, G | 1 |
| Ballardini, G; Martini, A; Ravelli, A; Ruperto, N; Villa, I; Viola, S | 1 |
| Horie, T; Matsukawa, Y; Nishinarita, S; Takahashi, N; Takei, M; Tomita, Y; Yamaguchi, M | 1 |
| Jih, DM; Werth, VP | 1 |
| Balduini, CL; Battaglia, M; Da Prada, GA; Gibelli, N; Noris, P; Pavesi, L; Pedrazzoli, P; Perotti, C; Preti, P; Robustelli della Cuna, G; Salvaneschi, L; Torretta, L; Zibera, C | 1 |
| Balduini, CL; Da Prada, GA; della Cuna, GR; Dornini, G; Livraghi, A; Noris, P; Pedrazzoli, P; Perotti, C; Salvaneschi, L; Torretta, L; Viarengo, G | 1 |
| Flombaum, CD; Meyers, PA | 1 |
| Auclerc, MF; Auvrignon, A; Baruchel, A; Bauduer, F; Berthou, C; Bordigoni, P; Demeocq, F; Lamagnere, JP; Landman-Parker, J; Leblanc, T; Legall, E; Leverger, G; Mathey, C; Michel, G; Pautard, B; Perel, Y; Schaison, G; Schneider, P | 1 |
| Benz, MS; Kramer, D; Murray, TG; Scott, IU; Toledano, S | 1 |
| Appelbaum, FR; Davis, C; Gooley, T; Nash, RA | 1 |
| Angelides, AG; Gang, DL; Kelleher, JF; Monteleone, PM; Steele, DA | 1 |
| Hosaka, M; Ikeda, I; Kawakami, S; Kubota, Y; Masuda, M; Noguchi, S; Ohuchi, H; Saito, K; Takase, K; Yao, M | 1 |
| Bernard, M; Casassus, P; Delain, M; Desablens, B; Guilhot, F; Hunault-Berger, M; Ifrah, N; Jouet, JP; Milpied, N; Sadoun, A | 1 |
| Izumi, Y; Kameyama, M; Sakoda, H; Udaka, F | 1 |
| Barcos, M; Bloomfield, CD; Freter, CE; Frizzera, G; Johnson, JL; Lee, EJ; Peterson, BA; Petroni, GR; Schiffer, CA | 1 |
| Chilcote, RR; Kadin, ME; Kjeldsberg, C; Krailo, MD; Meadows, AT; Morse, M; Siegel, SE; Sposto, R; Steinherz, PG; Termuhlen, AM | 1 |
| Katoh, S; Murayama, T; Nakazaki, S | 1 |
| Agata, S; Altavilla, G; De Nicolo, A; Girolami, A; Menin, C; Motta, G; Pietrogrande, F; Vianello, F | 1 |
| Alberto, P; Lehmann, W; Medenica, R | 1 |
| Bertrand, M; De Jager, R; Kenis, Y; Vanhaelen, C | 1 |
| Carr, DT; Hansen, HH; Sealy, R; Selawry, OS; Simon, R; Tucker, RD; van Wyk, CE | 1 |
| Chahinian, AP; Holland, JF; Jaffrey, IS; Mandel, EM; Teirstein, AS | 1 |
| Herson, J; Perez, C; Sutow, WW; Wang, YM | 1 |
| Banfi, A; Bonadonna, G; Rossi, A; Valagussa, P; Veronesi, U | 1 |
| McDonagh, J; McDonagh, RP; Rider, DM | 1 |
| Haggard, ME; Humphrey, GB; Lee, E; Sullivan, MP; Vietti, TJ | 1 |
| Girdwood, RH | 1 |
| Blomqvist, CP; Muhonen, TT; Pyrhönen, SO; Wiklund, TA | 1 |
| Alarcón, GS; Brooks, RH; Clegg, DO; Reading, JC; Singer, JZ; Skosey, JL; Ward, JR; Weisman, MH; Williams, HJ; Willkens, RF | 1 |
| Buzdar, AU; Forman, AD; Frye, DK; Holmes, FA; Hortobagyi, GN; Newton, LK; Raber, MN; Theriault, RL; Walters, RS | 1 |
| Boutan-Laroze, A; Caty, A; Charrot, P; Droz, JP; Fargeot, P; Kerbrat, P; Mahjoubi, M; Rey, A; Spielmann, M; Voisin, PM | 1 |
| Kaplan, MM; Knox, TA | 1 |
| Barlow, JF; Cullinan, S; Foley, JF; Kardinal, CG; Krook, JE; Moertel, CG; Norris, BD; Schutt, AJ; Tschetter, LK; Wieand, HS | 1 |
| Hill, BT; Price, LA | 1 |
| Campbell, JR; Maloley, PA; Montgomery, HA; Nelson, E | 1 |
| Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC | 1 |
| Igawa, M; Ishino, T; Kume, T; Masu, C; Nakatsu, H; Ohnishi, Y; Okada, K; Ueda, M; Ueki, T; Usui, T | 1 |
| Anderson, N; Beauchamp, K; Bern, M; Lokich, J; Moore, C; Wallach, S; Williams, D | 1 |
| Abeloff, MD; Berkman, AW; Markman, M; Waterfield, WC | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, HS; Hansen, M; Osterlind, K; Rørth, M | 1 |
| Cousar, JB; Greco, FA; Greer, JP; Hainsworth, JD; Stein, RS; Wolff, SN | 1 |
| Bruckner, H; Petrelli, NJ; Rustum, YM; Stablein, D | 1 |
| Anderson, J; Bloomfield, CD; Cooper, MR; Ginsberg, SJ; Gottlieb, AJ; Hurd, DD; Lachant, NA | 1 |
| Biron, P; Bouffet, E; Brunat-Mentigny, M; Frappaz, D; Kassir, A; Latour, JF; Philip, T | 1 |
| Brussaard, HE; de Wit, RF; van Eijk, CL; van Seters, WA; van Toorn, DW | 1 |
| Curt, G; Lokich, JJ | 1 |
| Curt, G; Green, R; Lokich, JJ; Paul, S; Phillips, D; Sonneborn, H; Zipoli, TE | 1 |
| Dold, U | 1 |
| Meister, H; Trux, F | 1 |
| Alberto, P; Broquet, MA; Jacot-Descombe, E; Montandon, A | 1 |
| Hansen, HH; Holland, JF; McCall, CB; Selawry, OS | 1 |
| Bertino, JR; DeConti, RC; Kaplan, SR; Mitchell, MS; Papac, R; Wawro, NW | 1 |
| Bennett, JM; Carbone, PP; Foley, HT | 1 |
| Scheiffarth, F; Warnatz, H | 1 |
| Landolt, AM | 1 |
| Shaw, MT | 1 |
| Alsarraf, D; Reese, L | 1 |
| Bernard, J; Blom, J; Boiron, M; Brunner, K; Cooper, MR; Cuttner, J; Ellison, RR; Gailani, S; Glidewell, OJ; Haurani, F; Holland, JF; Hoogstraten, B; Jacquillat, C; Levy, R; Lowenstein, L; Nissen, NI; Rege, VB; Serpick, AA; Silver, RT; Wasserman, L; Weil, M; Wiernik, PH | 1 |
| Gjemdal, T; Stavem, P | 1 |
| Blom, J; Stutz, FH; Tormey, DC | 1 |
| Bricteux, N | 1 |
| Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Stáva, Z | 1 |
| Gerner, RE; Moore, GE | 1 |
| Damascelli, B; De Palo, GM; Di Pietro, S; Gennari, L; Molinari, R | 1 |
| Canellos, GP; Chabner, BA; Devita, VT; Gold, GL; Schein, PS; Young, RC | 1 |
| Craig, JA | 1 |
| Amiel, JL; Cattan, A; de Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Rosenfeld, C; Schlumberger, JR; Schneider, M; Schwarzenberg, L | 1 |
| Dano, K; Nissen, NI | 1 |
| Curran, RE; Johnson, RE; Senyszyn, JJ | 1 |
| Block, JB; Carbone, PP; Haskell, CM; Leventhal, BG; Selawry, OS | 1 |
| Weiss, AJ; Wilson, WL | 1 |
| Maher, JF; Rath, CE; Schreiner, GE | 1 |
| Zubrod, CG | 1 |
| Braunsteiner, H; Schmalzl, F | 1 |
| Mazzi, R | 1 |
| Dawson, AA; Ogston, D | 1 |
| Rollier, MR | 1 |
| Bourgeois-Spinasse, J; Grupper, C | 1 |
| Frost, P; Weinstein, GD | 1 |
| Dawson, AA; Ogston, D; Philip, JF | 1 |
| Curtis, GH; Fowler-Bergfeld, W; Roenigk, HH | 1 |
9 review(s) available for methotrexate and Thrombopenia
| Article | Year |
|---|---|
Novel approach to decrease platelet exposure in a pediatric Jehovah Witness patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Jehovah's Witnesses; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Platelet Transfusion; Prednisone; Receptors, Fc; Recombinant Fusion Proteins; Remission Induction; Rituximab; Thrombocytopenia; Thrombopoietin; Treatment Refusal; Vincristine | 2019 |
Cytopenias among patients with rheumatic diseases using methotrexate: a meta-analysis of randomized controlled clinical trials.
Topics: Anemia; Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid; Humans; Leucovorin; Leukopenia; Methotrexate; Neutropenia; Pancytopenia; Randomized Controlled Trials as Topic; Rheumatic Diseases; Severity of Illness Index; Thrombocytopenia; Vitamin B Complex | 2020 |
The efficacy and safety comparison of first-line chemotherapeutic agents (high-dose methotrexate, doxorubicin, cisplatin, and ifosfamide) for osteosarcoma: a network meta-analysis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Leukopenia; Methotrexate; Network Meta-Analysis; Osteosarcoma; Survival Rate; Thrombocytopenia; Treatment Outcome | 2020 |
Baseline laboratory test abnormalities are common in early arthritis but rarely contraindicate methotrexate: study of three cohorts (ESPOIR, VErA, and Brittany).
Topics: Alanine Transaminase; Anemia; Antirheumatic Agents; Arthritis; Aspartate Aminotransferases; Cohort Studies; Contraindications; Diagnostic Tests, Routine; Early Diagnosis; Female; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Male; Methotrexate; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Thrombocytopenia | 2013 |
The limited efficacy of methotrexate, actinomycin D and cisplatin (MAP) for patients with advanced testicular cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cisplatin; Dactinomycin; Drug Administration Schedule; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Salvage Therapy; Testicular Neoplasms; Thrombocytopenia; Treatment Outcome | 2003 |
[Toxic lesions caused by cytostatic drugs].
Topics: Alopecia; Antineoplastic Agents; Arrhythmias, Cardiac; Blood Platelets; Blood Transfusion; Bone Marrow; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diarrhea; Digestive System; Doxorubicin; Female; Hair; Humans; Kidney Diseases; Lung; Male; Methotrexate; Methotrimeprazine; Mutation; Pericarditis; Pregnancy; Pulmonary Fibrosis; Thrombocytopenia; Vincristine | 1980 |
Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: results of cancer and leukemia group B study 9251.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infections; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survival Analysis; Thrombocytopenia; Vincristine | 2001 |
[Long-term therapy of immunologic diseases with special reference to the use of immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Antimetabolites; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Colitis, Ulcerative; Cyclophosphamide; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Methotrexate; Nephritis; Thrombocytopenia; Time Factors | 1969 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
46 trial(s) available for methotrexate and Thrombopenia
| Article | Year |
|---|---|
Ibrutinib-rituximab followed by R-HCVAD as frontline treatment for young patients (≤65 years) with mantle cell lymphoma (WINDOW-1): a single-arm, phase 2 trial.
Topics: Adenine; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Lymphoma, Mantle-Cell; Lymphopenia; Methotrexate; Middle Aged; Piperidines; Rituximab; Thrombocytopenia; Treatment Outcome; Vincristine | 2022 |
Comparison of two dose escalation strategies of methotrexate in active rheumatoid arthritis: a multicentre, parallel group, randomised controlled trial.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Polyglutamic Acid; Thrombocytopenia; Treatment Outcome; Young Adult | 2021 |
A multicenter phase II study incorporating high-dose rituximab and liposomal doxorubicin into the CODOX-M/IVAC regimen for untreated Burkitt's lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Polyethylene Glycols; Rituximab; Thrombocytopenia; Treatment Outcome; Vincristine; Young Adult | 2013 |
A phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine, and prednisolone for untreated elderly patients with primary central nervous system lymphoma. The GOELAMS LCP 99 trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Immunocompetence; Infections; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Palliative Care; Prednisolone; Recurrence; Remission Induction; Renal Insufficiency; Thrombocytopenia; Treatment Outcome; Vindesine | 2014 |
Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial.
Topics: Acute Kidney Injury; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Comparative Effectiveness Research; Cytarabine; Death, Sudden; Denmark; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Gastrointestinal Diseases; Germany; Heart Injuries; Hematopoietic Stem Cell Transplantation; Humans; Hyperglycemia; Induction Chemotherapy; Infections; Intraocular Lymphoma; Italy; Kaplan-Meier Estimate; Lymphoma, B-Cell; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Mucositis; Neurotoxicity Syndromes; Neutropenia; Optic Nerve Neoplasms; Poisoning; Radiotherapy, Adjuvant; Remission Induction; Rituximab; Stroke; Switzerland; Thiotepa; Thrombocytopenia; Thrombosis; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; United Kingdom | 2016 |
High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Karnofsky Performance Status; Leukopenia; Lomustine; Longitudinal Studies; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Pilot Projects; Procarbazine; Proportional Hazards Models; Radiotherapy, Adjuvant; Survival Analysis; Thrombocytopenia; Time Factors; Treatment Outcome | 2009 |
[Efficacy of modified B-NHL-BFM-90 protocol on anaplastic T-cell lymphoma in children and adolescents].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; L-Lactate Dehydrogenase; Leukopenia; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Neoplasm Staging; Remission Induction; Stem Cell Transplantation; Thrombocytopenia; Vincristine; Vindesine | 2009 |
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Juvenile; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Infections; Interleukin-1beta; Kaplan-Meier Estimate; Macrophage Activation Syndrome; Male; Methotrexate; Neutropenia; Thrombocytopenia | 2012 |
Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Docetaxel; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Prognosis; Taxoids; Thrombocytopenia; Treatment Outcome; Urologic Neoplasms; Vinblastine | 2004 |
[Clinical randomized comparative trial of ProMACE-CytaBOM regimen and CHOP regimen in treating non-Hodgkin's lymphoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Nausea; Prednisone; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine | 2005 |
Evaluation of toxicities induced by chemotherapy in breast cancer patients.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Breast Neoplasms; Cisplatin; Cohort Studies; Drug Evaluation; Drug Therapy, Combination; Erythrocyte Count; Erythrocytes; Female; Fluorouracil; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Leukocytes; Leukopenia; Methotrexate; Middle Aged; Pakistan; Platelet Count; Tamoxifen; Thrombocytopenia | 2005 |
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Lymphocytes; Male; Methotrexate; Middle Aged; Mucous Membrane; Nausea; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Prospective Studies; Rectal Neoplasms; Ribose-Phosphate Pyrophosphokinase; Thrombocytopenia; Vomiting | 1984 |
Comparison of chemotherapy alone versus chemotherapy and radiation therapy of extensive small cell carcinoma of the lung.
Topics: Aged; Body Weight; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Random Allocation; Thrombocytopenia | 1983 |
Treatment of patients with metastatic osteogenic sarcoma: a report from the Children's Cancer Study Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Neutropenia; Osteosarcoma; Thrombocytopenia; Time Factors; Vincristine | 1984 |
Randomized trial of cyclophosphamide, doxorubicin, and 5-fluorouracil alone or alternating with a "cycle active" non-cross-resistant combination in women with visceral metastatic breast cancer: a Southeastern Cancer Study Group project.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Nausea; Random Allocation; Thrombocytopenia; Vincristine; Vomiting | 1984 |
Efficacy of daunorubicin in the therapy of adult acute lymphocytic leukemia: a prospective randomized trial by cancer and leukemia group B.
Topics: Adult; Antibiotics, Antineoplastic; Asparaginase; B-Lymphocytes; Brain Neoplasms; Clinical Trials as Topic; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Male; Methotrexate; Naphthacenes; Neutropenia; Prednisone; Prognosis; Prospective Studies; Random Allocation; T-Lymphocytes; Thrombocytopenia; Vincristine | 1984 |
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Thrombocytopenia; Vomiting | 1984 |
Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma. A comparative trial of localized versus extensive radiotherapy including prophylactic brain irradiation in patients receiving combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Deglutition Disorders; Drug Therapy, Combination; Female; Hospitalization; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Radiotherapy; Thrombocytopenia | 1980 |
EORTC study of non-Hodgkin's lymphoma: phase III study comparing CHVmP-VB and ProMACE-MOPP in patients with stage II, III, and IV intermediate- and high-grade lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leucovorin; Life Tables; Lymphoma, Non-Hodgkin; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Procarbazine; Remission Induction; Survival Analysis; Teniposide; Thrombocytopenia; Treatment Outcome; Vincristine | 1994 |
Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Group stu
Topics: Agranulocytosis; Aminopterin; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Lung; Male; Methotrexate; Respiratory Distress Syndrome; Thrombocytopenia | 1995 |
Four-step high-dose sequential chemotherapy with double hematopoietic progenitor-cell rescue for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Etoposide; Feasibility Studies; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Methotrexate; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Neutropenia; Remission Induction; Thrombocytopenia; Vincristine | 1995 |
A pharmacologically guided phase I study of carboplatin in combination with methotrexate and vinblastine in advanced urothelial cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cell Count; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Neoplasms; Linear Models; Male; Methotrexate; Middle Aged; Neutropenia; Neutrophils; Thrombocytopenia; Ultrafiltration; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vinblastine | 1995 |
Short-term administration of granulocyte-macrophage colony stimulating factor decreases hematopoietic toxicity of cytostatic drugs.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Methotrexate; Middle Aged; Neutropenia; Thrombocytopenia | 1993 |
Carboplatin in combination as first-line therapy in advanced breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neutropenia; Thrombocytopenia | 1993 |
CVM versus ACE in the treatment of small cell lung cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Infant, Newborn; Infections; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia; Treatment Outcome; Vinblastine | 1993 |
A toxic interaction between mitomycin C and tamoxifen causing the haemolytic uraemic syndrome.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Interactions; Female; Hemolytic-Uremic Syndrome; Humans; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Retrospective Studies; Tamoxifen; Thrombocytopenia | 1993 |
Phase II study of sequential high-dose methotrexate (MTX) and 5-fluorouracil (F) alternated with epirubicin (E) and cisplatin (P) [FEMTX-P] in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Thrombocytopenia | 1993 |
Adults and children with small non-cleaved-cell lymphoma have a similar excellent outcome when treated with the same chemotherapy regimen.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Prednisone; Survival Analysis; Thrombocytopenia; Vincristine | 1996 |
Impact of recombinant human granulocyte colony stimulating factor on dose intensity and toxicity of three cycles of methotrexate, vinblastine, doxorubicin and cisplatin in patients with previously untreated urothelial bladder carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neutropenia; Recombinant Proteins; Stomatitis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 1996 |
Low-dose compared with standard-dose m-BACOD chemotherapy for non-Hodgkin's lymphoma associated with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; CD4 Lymphocyte Count; Cyclophosphamide; Dexamethasone; Doxorubicin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Survival Analysis; Thrombocytopenia; Vincristine | 1997 |
Use of recombinant human granulocyte colony-stimulating factor to increase chemotherapy dose-intensity: a randomized trial in very high-risk childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recombinant Proteins; Thrombocytopenia; Treatment Outcome; Vincristine | 2000 |
Daunorubicin continuous infusion induces more toxicity than bolus infusion in acute lymphoblastic leukemia induction regimen: a randomized study.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Infusions, Intravenous; Injections, Intravenous; Life Tables; Male; Methotrexate; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine | 2001 |
Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: results of cancer and leukemia group B study 9251.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infections; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survival Analysis; Thrombocytopenia; Vincristine | 2001 |
Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Prednisone; Recurrence; Stomatitis; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine | 2001 |
Vinblastine, methotrexate, bleomycin, in the management of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leukopenia; Methotrexate; Thrombocytopenia; Vinblastine | 1979 |
Combination chemotherapy of advanced lung cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukopenia; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Procarbazine; Thrombocytopenia; Vincristine | 1976 |
The CMF program for operable breast cancer with positive axillary nodes. Updated analysis on the disease-free interval, site of relapse and drug tolerance.
Topics: Amenorrhea; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Thrombocytopenia | 1977 |
Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis. A controlled clinical trial.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Auranofin; Double-Blind Method; Drug Therapy, Combination; Humans; Leukopenia; Methotrexate; Middle Aged; Thrombocytopenia | 1992 |
Phase II trial of taxol, an active drug in the treatment of metastatic breast cancer.
Topics: Adult; Aged; Agranulocytosis; Alkaloids; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Doxorubicin; Drug Evaluation; Female; Heart Diseases; Humans; Methotrexate; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Peripheral Nervous System Diseases; Remission Induction; Soft Tissue Neoplasms; Thrombocytopenia | 1991 |
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine | 1990 |
[M-VAC (methotrexate, vinblastine, adriamycin and cisplatin) chemotherapy in advanced renal pelvic and ureteral carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Evaluation; Female; Humans; Japan; Kidney Neoplasms; Kidney Pelvis; Leukopenia; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Remission Induction; Thrombocytopenia; Ureteral Neoplasms; Vinblastine | 1989 |
Chemotherapy versus chemotherapy plus irradiation in limited small cell lung cancer. Results of a controlled trial with 5 years follow-up.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Prognosis; Random Allocation; Thrombocytopenia; Vincristine | 1986 |
The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Diarrhea; Fluorouracil; Humans; Leucovorin; Leukopenia; Methotrexate; Random Allocation; Thrombocytopenia | 1988 |
Acute lymphocytic leukemia in children: maintenance therapy with methotrexat administered intermittently. Acute Leukemia Group B.
Topics: Adolescent; Adult; Blood Platelets; Bone Marrow Cells; Bone Marrow Examination; Child; Child, Preschool; Dyspnea; Female; Gastrointestinal Diseases; Hemoglobins; Herpesviridae Infections; Humans; Infant; Infant, Newborn; Infections; Injections, Intramuscular; Leukemia, Lymphoid; Leukocyte Count; Leukopenia; Male; Methotrexate; Mouth Diseases; Neurologic Manifestations; Osteoporosis; Pneumonia; Pneumonia, Pneumocystis; Prednisolone; Respiratory Tract Diseases; Thrombocytopenia; Vincristine | 1969 |
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.
Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine | 1972 |
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Radiography; Sarcoma, Ewing; Stomatitis; Suppuration; Thrombocytopenia; Vomiting | 1970 |
122 other study(ies) available for methotrexate and Thrombopenia
| Article | Year |
|---|---|
Half-dose glucarpidase as efficient rescue for toxic methotrexate levels in patients with acute kidney injury.
Topics: Acute Kidney Injury; Adult; Aged; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Middle Aged; Recombinant Proteins; Thrombocytopenia | 2022 |
Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis.
Topics: Abatacept; Adolescent; Arthritis; Autoantibodies; Azathioprine; Calcinosis; Child; Cyclophosphamide; Dermatomyositis; Female; Humans; Hyperplasia; Hypertension, Portal; Liver; Male; Methotrexate; Mycophenolic Acid; Prednisone; Rituximab; Splenomegaly; Thrombocytopenia; Transaminases; Young Adult | 2022 |
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Female; Humans; Immunosuppressive Agents; Incidence; Leflunomide; Liver Diseases; Male; Methotrexate; Middle Aged; Renal Insufficiency; Rheumatic Diseases; Thrombocytopenia; United Kingdom; Withholding Treatment | 2021 |
Ambulatory High-dose Methotrexate Administration in Pediatric Osteosarcoma Patients at a Single Institution in Argentina.
Topics: Adolescent; Algorithms; Ambulatory Care; Anemia; Antacids; Argentina; Chemical and Drug Induced Liver Injury; Child; Diarrhea; Female; Humans; Hydrogen-Ion Concentration; Leucovorin; Leukopenia; Male; Methotrexate; Mucositis; Neutropenia; Osteosarcoma; Retrospective Studies; Thrombocytopenia; Vomiting | 2017 |
Treatment of Combined Autoimmune Neutropenia and Immune Thrombocytopenia with Methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Autoantibodies; Autoimmune Diseases; Humans; Male; Methotrexate; Neutropenia; Neutrophils; Platelet Count; Thrombocytopenia | 2020 |
Alternative diagnosis to heparin-induced thrombocytopenia in two critically ill patients despite a positive PF4/heparin-antibody test.
Topics: Aged; Critical Illness; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; Femoral Neck Fractures; Heparin; Humans; Methotrexate; Pancytopenia; Penicillanic Acid; Piperacillin; Platelet Count; Platelet Factor 4; Purpura, Thrombocytopenic; Tazobactam; Thrombocytopenia; Transfusion Reaction | 2013 |
Clinical outcomes of patients with newly diagnosed primary central nervous system lymphoma are comparable on treatment with high-dose methotrexate plus temozolomide and with high-dose methotrexate plus cytarabine: a single-institution experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Temozolomide; Thrombocytopenia; Treatment Outcome; Young Adult | 2014 |
Extra-cranial giant cell arteritis: a diagnostic challenge.
Topics: Aged; C-Reactive Protein; Female; Giant Cell Arteritis; Humans; Methotrexate; Middle Aged; Platelet Transfusion; Positron-Emission Tomography; Prednisolone; Thrombocytopenia | 2015 |
Mercaptopurine metabolite levels are predictors of bone marrow toxicity following high-dose methotrexate therapy of childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythrocytes; Female; Guanine Nucleotides; Humans; Infant; Male; Mercaptopurine; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thionucleotides; Thrombocytopenia | 2015 |
Bilateral subdural hygromas following administration of intrathecal methotrexate chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dura Mater; Fatal Outcome; Humans; Injections, Spinal; Intracranial Hemorrhages; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Sepsis; Spinal Puncture; Subdural Effusion; Thrombocytopenia | 2015 |
Rituximab-induced acute thrombocytopenia: a case report and review of the literature.
Topics: Acute Disease; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Immunophenotyping; Infusions, Parenteral; L-Lactate Dehydrogenase; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Platelet Count; Rituximab; Splenomegaly; Thrombocytopenia; Vincristine | 2009 |
Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Humans; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neutropenia; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Thrombocytopenia | 2008 |
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Topics: Adolescent; Alleles; Anemia; Antimetabolites, Antineoplastic; Bone Marrow; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Gene Frequency; Genotype; Humans; Kidney; Liver; Lymphoma, Non-Hodgkin; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thrombocytopenia; Time Factors | 2009 |
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child, Preschool; Female; Folic Acid; Genotype; Humans; Lymphoma; Male; Metabolic Networks and Pathways; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mucositis; Nonlinear Dynamics; Odds Ratio; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Retrospective Studies; Thrombocytopenia | 2011 |
Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asian People; Child; Child, Preschool; China; Drug-Related Side Effects and Adverse Reactions; Female; Gene Frequency; Genotype; Haplotypes; Humans; Infant; Linkage Disequilibrium; Logistic Models; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neutropenia; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Skin Diseases; Thrombocytopenia | 2011 |
Adverse effects of low dose methotrexate in rheumatoid arthritis patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Age Distribution; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Blood Chemical Analysis; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Pancytopenia; Prognosis; Risk Assessment; ROC Curve; Severity of Illness Index; Sex Distribution; Thrombocytopenia; Young Adult | 2012 |
Fever of unknown origin in a patient of systemic onset juvenile idiopathic arthritis.
Topics: Adolescent; Anemia; Anti-Inflammatory Agents; Arthritis, Juvenile; Cyclosporine; Dexamethasone; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Thrombocytopenia | 2010 |
Life-threatening complications following multidose methotrexate for medical management of ectopic pregnancy.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Therapeutic; Adult; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leucovorin; Medical Errors; Methotrexate; Neutropenia; Pregnancy; Pregnancy, Ectopic; Recombinant Proteins; Respiration, Artificial; Sepsis; Shock; Thrombocytopenia; Vitamin B Complex | 2012 |
Association between polymorphisms of dihydrofolate reductase and gamma glutamyl hydrolase genes and toxicity of high dose methotrexate in children with acute lymphoblastic leukemia.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Female; gamma-Glutamyl Hydrolase; Gene Frequency; Genotype; Humans; Infant; Leukopenia; Male; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase; Thrombocytopenia | 2012 |
[Anesthetic management of a patient with thrombocytopenia induced by methotrexate undergoing emergent clipping surgery].
Topics: Aged; Anesthesia, General; Arthritis, Rheumatoid; Emergencies; Female; Humans; Immunosuppressive Agents; Intracranial Aneurysm; Leucovorin; Methotrexate; Piperidines; Platelet Transfusion; Postoperative Care; Propofol; Remifentanil; Subarachnoid Hemorrhage; Thrombocytopenia; Treatment Outcome; Vascular Surgical Procedures | 2012 |
Efficacy of a dose-intensified CHOP (Double-CHOP) regimen for peripheral T-cell lymphomas.
Topics: Adolescent; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Lymphoma, T-Cell, Peripheral; Male; Methotrexate; Middle Aged; Neutropenia; Prednisone; Retrospective Studies; Risk Factors; Stem Cell Transplantation; Survival Rate; Thrombocytopenia; Transplantation, Autologous; Vincristine; Young Adult | 2013 |
Salvage treatment with etoposide (VP-16), ifosfamide and cytarabine (Ara-C) for patients with recurrent primary central nervous system lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child, Preschool; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Ifosfamide; Life Tables; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thrombocytopenia; Vincristine | 2003 |
IMMUNOSUPPRESSIVE DRUG THERAPY IN CANINE RENAL AND SKIN HOMOGRAFTS.
Topics: Allergy and Immunology; Allografts; Animals; Azaserine; Dactinomycin; Dogs; Immunosuppressive Agents; Kidney Transplantation; Leukopenia; Methotrexate; Purines; Pyrazoles; Pyrimidines; Research; Skin Transplantation; Thrombocytopenia; Urea | 1963 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria | 1964 |
ASSOCIATION OF HERPES ZOSTER WITH LEUKEMIA AND LYMPHOMA IN CHILDREN.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Child; Cyclophosphamide; Drug Therapy; Herpes Zoster; Hodgkin Disease; Leukemia; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Prednisolone; Surgical Procedures, Operative; Thrombocytopenia | 1965 |
Urinary tract infections and lupus erythematosus.
Topics: Adult; Age Factors; Antibodies, Antinuclear; Antirheumatic Agents; Escherichia coli; Female; Hospitalization; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Prevalence; Prospective Studies; Recurrence; Risk Factors; Thrombocytopenia; Urinary Tract Infections | 2004 |
[Clinical study of modified M-VAC therapy with one 21-day cycle for advanced urothelial cancer].
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neutropenia; Thrombocytopenia; Urologic Neoplasms; Vinblastine | 2004 |
Kernohan notch lesion after spinal tap.
Topics: Adult; Causality; Cerebral Veins; Disease Progression; Efferent Pathways; Female; Headache; Hematoma, Subdural, Intracranial; Hemiplegia; Humans; Injections, Spinal; Intracranial Hypotension; Magnetic Resonance Imaging; Mesencephalon; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Puncture; Thrombocytopenia | 2005 |
The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anemia; Antirheumatic Agents; Australia; Carbamazepine; Child; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Humans; Incidence; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Neutropenia; Organogold Compounds; Pancytopenia; Thrombocytopenia | 2007 |
Can dantrolene contribute to methotrexate toxicity?
Topics: Acute Kidney Injury; Adolescent; Chemical and Drug Induced Liver Injury; Dantrolene; Drug Interactions; Female; Humans; Methotrexate; Mucositis; Thrombocytopenia | 2006 |
Clinical problem-solving. Lost in transcription.
Topics: Bone Marrow; Diagnosis, Differential; Female; Fever; Hematuria; Humans; Immunosuppressive Agents; Leukopenia; Medical Records Systems, Computerized; Medication Errors; Methotrexate; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Thrombocytopenia; Urinary Catheterization; Urination Disorders | 2006 |
Adverse drug reaction to methotrexate: pharmacogenetic origin.
Topics: Antimetabolites, Antineoplastic; Female; Genetic Predisposition to Disease; Genotype; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mucositis; Neutropenia; Pharmacogenetics; Polymorphism, Single Nucleotide; Thrombocytopenia | 2006 |
Adverse events of MVAC chemotherapy in patients with advanced urothelial cancer of the bladder.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neutropenia; Retrospective Studies; Serotonin Antagonists; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 2007 |
[MTX-HOPE (methotrexate, hydrocortisone, vincristine, sobuzoxane, and etoposide) as a low-dose salvage chemotherapy for recurrent or refractory non-Hodgkin's lymphoma].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Hydrocortisone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Piperazines; Salvage Therapy; Survival Rate; Thrombocytopenia; Vincristine | 2007 |
Clinical evaluation of two combination chemotherapies for the treatment of small cell carcinoma of the lung.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nimustine; Nitrosourea Compounds; Pulmonary Fibrosis; Thrombocytopenia; Vincristine | 1984 |
Acute bleomycin and methotrexate toxicity: report of two cases.
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Gingivitis, Necrotizing Ulcerative; Humans; Hypotension; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Thrombocytopenia | 1982 |
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia | 1983 |
Modified triple chemotherapy in the management of high-risk metastatic gestational trophoblastic tumors.
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin; Cisplatin; Cyclophosphamide; Dactinomycin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Pregnancy Complications, Neoplastic; Risk; Thrombocytopenia; Trophoblastic Neoplasms; Uterine Neoplasms; Vinblastine | 1984 |
Methotrexate with citrovorum factor rescue as primary therapy for gestational trophoblastic disease.
Topics: Adolescent; Adult; Agranulocytosis; Chemical and Drug Induced Liver Injury; Dactinomycin; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Middle Aged; Neoplasm Metastasis; Pregnancy; Thrombocytopenia; Trophoblastic Neoplasms; Uterine Neoplasms | 1982 |
High-dose methotrexate in small cell lung cancer. Lack of efficacy in preventing CNS relapse.
Topics: Aged; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nervous System Neoplasms; Paraneoplastic Syndromes; Smoking; Thrombocytopenia | 1983 |
Treatment of metastatic colorectal carcinoma with 5-FU, mitomycin, vincristine, and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Thrombocytopenia; Vincristine | 1984 |
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mitolactol; Mitomycins; Nausea; Prednisone; Soft Tissue Neoplasms; Thrombocytopenia; Time Factors; Vincristine; Vomiting | 1984 |
[Chemotherapy of metastasizing breast cancer. Adriamycin mono and combination therapy after LMFP pretreatment].
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Thrombocytopenia; Vincristine | 1983 |
Chemotherapy for metastatic transitional carcinoma of the urinary tract. A prospective trial of methotrexate, adriamycin, and cyclophosphamide (MAC) with cis-platinum for failure.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Inflammation; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane; Prospective Studies; Thrombocytopenia; Urologic Neoplasms | 1983 |
The treatment of histiocytic lymphoma.
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leucovorin; Leukopenia; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Prednisone; Procarbazine; Radiotherapy, High-Energy; Thrombocytopenia; Vincristine | 1980 |
Clinical pharmacology of methotrexate.
Topics: Animals; Creatinine; Half-Life; Haplorhini; Humans; Intestinal Absorption; Kidney; Leukopenia; Liver; Methotrexate; Rats; Thrombocytopenia; Tissue Distribution | 1981 |
VP-16 and adriamycin in patients with advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prednisone; Thrombocytopenia; Vincristine; Vomiting | 1982 |
Prophylactic oral methotrexate therapy for multiple superficial bladder carcinoma.
Topics: Administration, Oral; Carcinoma, Transitional Cell; Humans; Methotrexate; Neoplasm Recurrence, Local; Stomatitis, Aphthous; Thrombocytopenia; Urinary Bladder Neoplasms | 1981 |
M-VEC (methotrexate, vinblastine, 4'-epirubicin and cisplatin) combined with glycosylated recombinant human granulocyte colony-stimulating factor (rhG-CSF) for the treatment of transitional cell carcinoma of urothelium: reduction in toxicity produced by r
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Epirubicin; Female; Glycosylation; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Recombinant Proteins; Survival Analysis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 1994 |
Haemophagocytic lymphohistiocytosis: experience at two U.K. centres.
Topics: Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Drug Therapy, Combination; Etoposide; Female; Fibrinogen; Follow-Up Studies; Histiocytosis, Non-Langerhans-Cell; Humans; Infant; Infant, Newborn; Male; Methotrexate; Methylprednisolone; Retrospective Studies; Survival Analysis; Thrombocytopenia; Treatment Outcome; United Kingdom | 1994 |
High-dose, brief duration, multiagent chemotherapy for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hemorrhage; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Survival Rate; Thrombocytopenia | 1994 |
Introduction of a new tracheostomy exchange device after percutaneous tracheostomy in a patient with coagulopathy.
Topics: Adult; Blood Coagulation Disorders; Bone Marrow Transplantation; Equipment Design; Humans; Male; Methotrexate; Mouth Mucosa; Respiratory Insufficiency; Stomatitis; Thrombocytopenia; Tracheostomy | 1996 |
Thrombocytopenia in patients with rheumatoid arthritis on long-term treatment with low dose methotrexate.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Leukocyte Count; Methotrexate; Middle Aged; Platelet Count; Retrospective Studies; Thrombocytopenia | 1996 |
Thrombocytopenia in patients with rheumatoid arthritis on long-term treatment with low dose methotrexate.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Methotrexate; Middle Aged; Retrospective Studies; Thrombocytopenia; Time Factors | 1996 |
Cervical spontaneous epidural hematoma as a complication of non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Hematoma, Epidural, Cranial; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Spinal Cord Compression; Thrombocytopenia; Vincristine | 1996 |
[Toxicity of high dose methotrexate repeated infusions in children treated for acute lymphoblastic leukemia and osteosarcoma].
Topics: Antineoplastic Agents; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Kidney; Liver; Methotrexate; Neutropenia; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thrombocytopenia | 1996 |
Isolated thrombocytopenia associated with low dose methotrexate therapy.
Topics: Aged; Antirheumatic Agents; Humans; Male; Methotrexate; Thrombocytopenia | 1997 |
Methotrexate therapy in refractory pediatric onset systemic lupus erythematosus.
Topics: Adolescent; Age of Onset; Antirheumatic Agents; Child; Female; Folic Acid Antagonists; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Nephritis; Thrombocytopenia; Treatment Outcome | 1998 |
Successful methotrexate therapy for adult Still's disease with marked thrombocytopenia.
Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Methotrexate; Still's Disease, Adult-Onset; Thrombocytopenia | 1998 |
Thrombocytopenia after a single test dose of methotrexate.
Topics: Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Methotrexate; Skin Diseases; Thrombocytopenia | 1998 |
Autologous platelet transfusion in patients receiving high-dose chemotherapy and circulating progenitor cell transplantation for stage II/III breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fever; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Inflammation; Methotrexate; Middle Aged; Mucous Membrane; Platelet Count; Platelet Transfusion; Plateletpheresis; Thrombocytopenia; Transplantation Conditioning; Treatment Outcome; Vincristine | 1998 |
Autologous platelet collection and storage to support thrombocytopenia in patients undergoing high-dose chemotherapy and circulating progenitor cell transplantation for high-risk breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Blood Preservation; Blood Transfusion, Autologous; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Methotrexate; Platelet Transfusion; Thiotepa; Thrombocytopenia | 1998 |
High-dose leucovorin as sole therapy for methotrexate toxicity.
Topics: Antidotes; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Creatinine; Drug Administration Schedule; Female; Folic Acid Antagonists; Humans; Kidney; Leucovorin; Methotrexate; Neutropenia; Osteosarcoma; Retrospective Studies; Thrombocytopenia | 1999 |
Complications of systemic chemotherapy as treatment of retinoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cyclosporine; Cytarabine; Etoposide; Female; Fever; Humans; Infant; Male; Methotrexate; Neutropenia; Organophosphorus Compounds; Retinal Neoplasms; Retinoblastoma; Thrombocytopenia; Vincristine | 2000 |
The problem of thrombocytopenia after hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow Transplantation; Child; Child, Preschool; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk; Risk Factors; Sex Factors; Thrombocytopenia; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1996 |
Hepatic dysfunction as the presenting feature of acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biopsy; Child, Preschool; Cholestasis, Intrahepatic; Chromosome Deletion; Daunorubicin; Hepatomegaly; Humans; Liver; Liver Function Tests; Male; Mercaptopurine; Methotrexate; Practice Guidelines as Topic; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Thrombocytopenia; Ultrasonography; Vincristine | 2001 |
[Study of neoadjuvant chemotherapy for invasive bladder cancer with MEC (methotrexate, epirubicin, cisplatin) therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Drug Administration Schedule; Epirubicin; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Prognosis; Survival Analysis; Thrombocytopenia; Urinary Bladder Neoplasms | 2001 |
[A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis].
Topics: Adult; Amphotericin B; Antifungal Agents; Antiphospholipid Syndrome; Female; Flucytosine; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Meningitis, Cryptococcal; Methotrexate; Prednisolone; Thrombocytopenia; Thrombophlebitis | 2001 |
[Cytopenia associated with low dose pulse methotrexate in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Pancytopenia; Pulse Therapy, Drug; Thrombocytopenia | 2001 |
Hepatosplenic gammadelta T-cell lymphoma presenting with immune-mediated thrombocytopenia and hemolytic anemia (Evans' syndrome).
Topics: Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Autoimmune Diseases; Biopsy; Bleomycin; Blood Platelets; Bone Marrow; Cyclophosphamide; Doxorubicin; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Hepatomegaly; Humans; Hydrocortisone; Leucovorin; Liver Neoplasms; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Prednisone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Splenic Neoplasms; Splenomegaly; Syndrome; Thrombocytopenia; Vincristine | 2002 |
[Treatment of disseminated oro-pharyngo-laryngeal epidermoid carcinomas with a combination of methotrexate and bleomycine in small doses].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Lung Diseases; Methotrexate; Thrombocytopenia | 1976 |
MACC (methotrexate, adriamycin, cyclophosphamide and CCNU) in advanced lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Drug Therapy, Combination; Female; Heart Diseases; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia | 1979 |
Evaluation of overall toxicity of high-dosage methotrexate regimens.
Topics: Adolescent; Age Factors; Bone Marrow; Bone Neoplasms; Child; Dermatitis; Drug Administration Schedule; Female; Humans; Kidney; Leucovorin; Leukopenia; Liver; Male; Methotrexate; Osteosarcoma; Sex Factors; Stomatitis; Thrombocytopenia; Vincristine | 1979 |
A possible contributory role of the platelet in the formation of plasma factor XIII.
Topics: Animals; Blood Cell Count; Blood Platelets; Cyclophosphamide; Factor XIII; Fibrinogen; Male; Methotrexate; Quinidine; Rats; Thrombocytopenia; Vincristine | 1978 |
Superiority of conventional intrathecal methotrexate therapy with maintenance over intensive intrathecal methotrexate therapy, unmaintained, or radiotherapy (2000-2500 rads tumor dose) in treatment for meningeal leukemia.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Humans; Injections, Spinal; Leukemia; Meninges; Methotrexate; Radiotherapy Dosage; Radiotherapy, High-Energy; Remission, Spontaneous; Thrombocytopenia; Time Factors | 1975 |
The nature of possible adverse reactions to co-trimoxazole.
Topics: Aminopterin; Anemia, Megaloblastic; Chemical Phenomena; Chemistry; Drug Combinations; Folic Acid; Humans; Methotrexate; Pyrimethamine; Sulfamethoxazole; Thrombocytopenia; Trimethoprim; Vitamin B 12 | 1976 |
Unexpected prolonged myelosuppression after mitomycin, mitoxantrone and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Thrombocytopenia; Time Factors | 1992 |
M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for advanced carcinoma of the bladder. The French Federation of Cancer Centers experience.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Male; Methotrexate; Middle Aged; Prognosis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 1991 |
Treatment of primary biliary cirrhosis with low-dose weekly methotrexate.
Topics: Adult; Alkaline Phosphatase; Bilirubin; Biopsy; Cholesterol; Drug Evaluation; Fatigue; Female; Follow-Up Studies; Humans; Leukopenia; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged; Pruritus; Thrombocytopenia; Transaminases | 1991 |
Higher average received relative dose intensities of cyclophosphamide, methotrexate and 5-fluorouracil using a 24-hour method: implications for improved cure rates in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Remission Induction; Thrombocytopenia; Vincristine | 1990 |
Severe reversible thrombocytopenia resulting from butoconazole cream.
Topics: Administration, Intravaginal; Antifungal Agents; Female; Humans; Ibuprofen; Imidazoles; Methotrexate; Middle Aged; Ointments; Thrombocytopenia | 1990 |
Short term high density systemic therapy for metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluoxymesterone; Humans; Leucovorin; Leukopenia; Lung; Methotrexate; Mitolactol; Neoplasm Metastasis; Prednisone; Receptors, Estrogen; Tamoxifen; Thrombocytopenia; Time Factors; Vincristine | 1985 |
Cyclophosphamide, methotrexate, and 5-fluorouracil in a three-drug admixture. Phase I trial of 14-day continuous ambulatory infusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Stability; Fluorouracil; Humans; Infusions, Intravenous; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia | 1989 |
Intensive alternating chemotherapy regimen in small cell carcinoma of the lung.
Topics: Actuarial Analysis; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Gastrointestinal Hemorrhage; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia; Vincristine | 1985 |
Effects of Mega-COMLA (cyclophosphamide, cytarabine, vincristine, and methotrexate followed by leucovorin and prednisone) plus CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in the treatment of lymphoid neoplasms with very poor prognosi
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Staging; Neutropenia; Peripheral Nervous System Diseases; Prednisone; Prognosis; Thrombocytopenia; Vincristine | 1986 |
Treatment of refractory lymphoma with methotrexate, VM-26 (teniposide), procarbazine, and dexamethasone: Cancer and Leukemia Group B study 7902.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Evaluation; Female; Humans; Leucovorin; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Procarbazine; Teniposide; Thrombocytopenia; Vincristine | 1988 |
[Methotrexate poisoning: value of exchange transfusion].
Topics: Acute Kidney Injury; Child; Exchange Transfusion, Whole Blood; Humans; Leukopenia; Male; Methotrexate; Osteosarcoma; Thrombocytopenia | 1987 |
[Acute bone marrow suppression with low-dosage methotrexate].
Topics: Aged; Arthritis, Rheumatoid; Bone Marrow; Female; Half-Life; Humans; Leukopenia; Methotrexate; Pancytopenia; Psoriasis; Thrombocytopenia | 1987 |
A phase I and pharmacology study of continuous-infusion low-dose methotrexate administration.
Topics: Adult; Aged; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia | 1985 |
5-Fluorouracil and methotrexate administered simultaneously as a continuous infusion. A phase I study.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia | 1985 |
[Cytostatic therapy of bronchial carcinoma].
Topics: Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Humans; Leukopenia; Methotrexate; Palliative Care; Procarbazine; Thrombocytopenia; Triaziquone; Vincristine | 1972 |
[Immature cell panmyelosis].
Topics: Acid Phosphatase; Adult; Antibiotics, Antineoplastic; Asparaginase; Blood Transfusion; Bone Marrow Examination; Daunorubicin; Drug Combinations; Esterases; Glucuronidase; Hematologic Diseases; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Male; Megakaryocytes; Methotrexate; Peroxidases; Prednisolone; Spleen; Staining and Labeling; Thrombocytopenia; Vincristine | 1973 |
[Treatment of epidermoid carcinoma of the oro-pharyngo-laryngeal area with combination of methotrexate and bleomycin].
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms; Thrombocytopenia | 1974 |
The variability of individual tolerance to methotrexate in cancer patients.
Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting | 1971 |
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
Combination chemotherapy in accelerated phase of chronic granulocytic leukemia.
Topics: Adolescent; Adult; Aged; Anemia; Blood Platelets; Blood Transfusion; Blood Urea Nitrogen; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytomegalovirus; Female; Fever; Hemorrhage; Humans; Jaundice; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nocardia Infections; Pneumonia; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Thrombocytopenia; Vincristine | 1969 |
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia | 1971 |
The effect of methotrexate and folinic acid therapy on the platelet count.
Topics: Blood Cell Count; Blood Platelets; Female; Humans; Leucovorin; Methotrexate; Pregnancy; Thrombocytopenia; Thrombocytosis; Time Factors; Trophoblastic Neoplasms; Uterine Neoplasms | 1973 |
Management of acute renal failure due to marked hyperuricemia.
Topics: Acute Kidney Injury; Adolescent; Allopurinol; Bicarbonates; Humans; Infusions, Parenteral; Kidney; Leukemia, Lymphoid; Male; Methotrexate; Potassium; Prednisone; Radiography; Regional Blood Flow; Renal Dialysis; Sodium; Thrombocytopenia; Uric Acid; Vincristine | 1972 |
Daunorubicin in the therapy of acute granulocytic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Female; Humans; Hydrazines; Hyperplasia; Leukemia, Myeloid; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thrombocytopenia; Time Factors | 1973 |
Acute leukemia in adults.
Topics: Adult; Agranulocytosis; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Thrombocytopenia; Time Factors | 1973 |
Combination chemotherapy in disseminated carcinoma of the breast.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Feeding and Eating Disorders; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Nausea; Neoplasm Metastasis; Pneumonia; Prednisone; Thrombocytopenia; Vincristine | 1974 |
[Treatment of complications induced by chemotherapy of acute leukemias].
Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Antineoplastic Agents; Asparaginase; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hemorrhage; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Prednisone; Thrombocytopenia; Vincristine | 1974 |
Methrotrexate U.S.P. (amethopterin) and methotrexate sodium.
Topics: Abortion, Induced; Anemia; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Choriocarcinoma; Drug Interactions; Female; Humans; Leukemia; Leukopenia; Male; Methotrexate; Neoplasms; Pregnancy; Psoriasis; Skin Diseases; Testicular Neoplasms; Thrombocytopenia; Uric Acid; Uterine Neoplasms | 1973 |
[Methotrexate in the therapy of psoriasis].
Topics: Fever; Gastrointestinal Diseases; Humans; Methotrexate; Psoriasis; Thrombocytopenia | 1973 |
Multiple-drug therapy for malignant solid tumors in adults.
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Vincristine | 1973 |
Cancer chemotherapy by intra-arterial infusion with adriamycin.
Topics: Adult; Alopecia; Anemia; Doxorubicin; Electrocardiography; Female; Femoral Artery; Fluorouracil; Heart; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Thrombocytopenia | 1973 |
Cyclical combination chemotherapy for advanced breast carcinoma.
Topics: Adrenalectomy; Adult; Alopecia; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lung Neoplasms; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thrombocytopenia | 1974 |
Jaundice in acute pustular psoriasis.
Topics: Arthropathy, Neurogenic; Bilirubin; Chemical and Drug Induced Liver Injury; Clindamycin; Female; Fusidic Acid; Humans; Jaundice; Leukocytosis; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1974 |
[A new combination of methotrexate and folinic acid for cancer treatment (acute leukemia and solid tumors)].
Topics: Agranulocytosis; Antineoplastic Agents; Breast Neoplasms; Female; Hemangiosarcoma; Hodgkin Disease; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Osteosarcoma; Pancreatic Neoplasms; Radiography; Rectal Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Thrombocytopenia | 1969 |
Clinical experience with L-asparaginase.
Topics: Adolescent; Adult; Aged; Asparaginase; Azaserine; Burkitt Lymphoma; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Escherichia coli; Female; Humans; Leukemia, Lymphoid; Leukopenia; Lymphoma, Non-Hodgkin; Lymphopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms; Pancreatitis; Thrombocytopenia | 1970 |
Evaluation of the combination of hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in carcinoma of the lung.
Topics: Administration, Oral; Amines; Antineoplastic Agents; Carcinoma, Bronchogenic; Diarrhea; Evaluation Studies as Topic; Humans; Injections, Intramuscular; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Remission, Spontaneous; Stomatitis; Thrombocytopenia; Triazines; Vomiting | 1971 |
Hyperuricemia complicating leukemia: treatment with allopurinol and dialysis.
Topics: Acetazolamide; Acute Kidney Injury; Adult; Allopurinol; Anuria; Bicarbonates; Blood Gas Analysis; Blood Urea Nitrogen; Carbon Dioxide; Cystoscopy; Electroencephalography; Eye Manifestations; Female; Humans; Leukemia, Lymphoid; Leukocytosis; Mannitol; Mercaptopurine; Methotrexate; Peritoneal Dialysis; Prednisone; Splenomegaly; Thrombocytopenia; Uric Acid; Urinary Catheterization; Vincristine; Water-Electrolyte Balance | 1969 |
The treatment of acute lymphocytic leukemia.
Topics: Animals; Antineoplastic Agents; Asparaginase; Blood Platelets; Bone Marrow Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Synergism; Hemorrhage; Humans; Infections; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mice; Prednisone; Prognosis; Thrombocytopenia; Vincristine | 1970 |
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine | 1971 |
[Experience with methotrexate in the management of psoriasis].
Topics: Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous; Methotrexate; Nausea; Psoriasis; Thrombocytopenia; Time Factors | 1969 |
Thrombocytosis following thrombocytopenia in man.
Topics: Anemia, Pernicious; Humans; Methotrexate; Neoplasms; Prednisone; Purpura, Thrombocytopenic; Thrombocytopenia; Thrombocytosis; Vitamin B 12 | 1969 |
[72 cases of psoriasis treated by methotrexate].
Topics: Adolescent; Adult; Biopsy; Child; Female; Humans; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Thrombocytopenia | 1969 |
[Methotrexate in the treatment of psoriasis].
Topics: Adult; Aged; Asthenia; Chemical and Drug Induced Liver Injury; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1970 |
Methotrexate for psoriasis. A new therapeutic schedule.
Topics: Administration, Oral; Alopecia; Humans; Injections, Intramuscular; Leukopenia; Methotrexate; Mouth Diseases; Nausea; Prognosis; Psoriasis; Thrombocytopenia; Ulcer; Urticaria | 1971 |
Methotrexate and the platelet count.
Topics: Antineoplastic Agents; Azathioprine; Blood Cell Count; Blood Platelets; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Thrombocytosis; Time Factors | 1968 |
Methotrexate for psoriasis in weekly oral doses.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anemia; Aspartate Aminotransferases; Child; Female; Folic Acid Antagonists; Follow-Up Studies; Humans; Kidney Function Tests; Leukopenia; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1969 |