Page last updated: 2024-08-25

methotrexate and Stroke

methotrexate has been researched along with Stroke in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (9.09)29.6817
2010's24 (72.73)24.3611
2020's6 (18.18)2.80

Authors

AuthorsStudies
Astorquizaga, L; Cheistwer, A; Font, D; Marin, F; Palmieri, F1
Andión-Catalán, M; García-Salido, A; Lassaleta-Atienza, Á; Leoz-Gordillo, I; López-De Suso, D; Sirvent-Cerdá, S1
Almeida, JR; Brouwer, ES; Burn, E; Carmona, L; Chatzidionysiou, K; Duarte-Salles, T; Fakhouri, W; Hottgenroth, A; Jani, M; Kolde, R; Kors, JA; Kullamaa, L; Lane, J; Marinier, K; Michel, A; Prats-Uribe, A; Prieto-Alhambra, D; Reisberg, S; Rijnbeek, PR; Ryan, P; Sena, AG; Stewart, HM; Swerdel, JN; Torre, CO; Verhamme, K; Vizcaya, D; Weaver, J; Williams, RD; Yang, C1
Schmidt, WA1
Kaneko, Y; Takanashi, S; Takeuchi, T1
Anderson, DR; Baker, JF; England, BR; George, MD; Johnson, TM; Liao, KP; Mikuls, TR; Roul, P; Sauer, B; Sayles, HR; Zheng, C1
Boehm, M; Hallenbeck, J; Hollander, MC; Ishii, H; Latour, LL; Lin, PC; Merchant, AS; Min, Y; Munasinghe, J; Ray-Choudhury, A; Xiao, Z; Yang, D; Yang, L1
Akbaraly, T; Deneux, V; Haouy, S; Leboucq, N; Saumet, L; Sirvent, N1
Kanfi, A; Samanta, D; Willis, E1
Chen, CH; Chen, CM; Chiou, JY; Leong, PY; Li, YC; Lin, LC; Tam, HW; Wang, YH; Wei, JC1
Ago, T; Kitayama, J; Kitazono, T; Okata, T; Sambongi, Y; Tanimoto, K; Yamanaka, I; Yamanaka, K1
Arakawa, Y; Hanada, R; Ikeda, Y; Isobe, K; Koh, K; Mori, M; Oguma, E; Oyama, C; Sasaki, K; Uehara, T; Watanabe, K; Yanagi, M1
Bertrand, O; Butman, S; Clearfield, M; Everett, BM; Glynn, RJ; Goldhaber, SZ; Gupta, M; Hasan, A; Iturriaga, E; Johnston, J; Le May, M; Libby, P; MacFadyen, JG; Mam, V; Ofori, C; Paynter, NP; Pradhan, A; Ridker, PM; Rosenberg, Y; Saklayen, M; Seagle, R; Singh, N; Solomon, DH; Tsigoulis, M; Verma, S; Zaharris, E1
Evers, D; Klijn, CJM; Maas, RPPWM; Pegge, SAH; van Samkar, A1
Cossburn, MD; Harris, MJ; Pengas, G1
Ridker, PM1
Goyal, M; Pandey, A1
Chen, L; Curtis, JR; Graham, DJ; Griffin, MR; Harrold, LR; Herrinton, LJ; Kowal, MK; Kuriya, B; Lewis, JD; Lii, J; Liu, L; Rassen, JA; Saag, KG; Solomon, DH1
Ahlehoff, O; Bryld, LE; Gislason, G; Gniadecki, R; Hansen, PR; Iversen, L; Kristensen, SL; Lasthein, S; Lindhardsen, J; Skov, L; Torp-Pedersen, C1
Baud, JM; Chadenat, ML; Herlin, B; Pico, F1
Ambrosetti, A; Balzarotti, M; Binder, M; Cavalli, F; Cwynarski, K; Deckert, M; Fabbri, A; Ferrari, A; Ferreri, AJ; Finke, J; Fox, CP; Gørløv, JS; Hemmaway, C; Hertenstein, B; Hess, G; Illerhaus, G; Johnson, P; Keller, U; Krause, SW; Levis, A; Linton, KM; Panse, J; Pisani, F; Politi, LS; Ponzoni, M; Pukrop, T; Pulczynski, E; Reni, M; Rosée, PL; Roth, A; Rudà, R; Schmoll, HJ; Schorb, E; Stilgenbauer, S; Torri, V; Tucci, A; Zucca, E1
Ho, A; Kurtzman, DJ; Rubenstein, MH; Vleugels, RA; Wright, NA1
Cloutier, M; Dea, K; Guérin, A; Mulani, P; Sundaram, M; Wu, JJ1
Drachtman, RA; Haines, C; Pan, WJ; Rogers, P1
Alpern, ER; Thomas, N1
El-Hakam, LM; Illner, A; Ramocki, MB; Riviello, JJ1
Agarwal, A; Ouyang, T; Thamburaj, K; Vijay, K1
Hattori, N; Nishioka, K; Sasaki-Ikesawa, K; Shimura, H; Tanaka, R; Tanaka, S1
Daïen, CI; Fesler, P1
Bond, J; Goulden, N; Hough, R; Mitchell, C; Moppett, J; Vora, A1
Baldini, L; Balzarotti, M; Bernardi, M; Bobbio, F; Brandes, AA; Caligaris Cappio, F; Corazzelli, G; Dell'Oro, S; Ferreri, AJ; Foppoli, M; Ilariucci, F; Montanari, M; Picozzi, P; Ponzoni, M; Reni, M; Spina, M; Stelitano, C; Tosoni, A; Zaja, F1
Baehring, JM; Fulbright, RK1

Reviews

4 review(s) available for methotrexate and Stroke

ArticleYear
Methotrexate-induced stroke-like neurotoxicity: Case report, 8 years of experience, and literature review.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:9

    Topics: Antimetabolites, Antineoplastic; Humans; Methotrexate; Neurotoxicity Syndromes; Stroke

2022
[Inflammatory Muscle Pain: Polymyalgia Rheumatica with or without Large Vessel Vasculitis].
    Deutsche medizinische Wochenschrift (1946), 2020, Volume: 145, Issue:13

    Topics: Aged; Antibodies, Monoclonal, Humanized; Blindness; Diagnosis, Differential; Fatigue; Female; Giant Cell Arteritis; Humans; Methotrexate; Polymyalgia Rheumatica; Prednisolone; Stroke; Ultrasonography; Vasculitis

2020
Anticytokine Agents: Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis
    Circulation research, 2019, Volume: 124, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Diabetes Mellitus, Type 2; Disease Models, Animal; Hematopoiesis; Humans; Inflammasomes; Interleukin-18; Interleukin-1beta; Interleukin-6; Methotrexate; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Signal Transduction; Stroke; Thrombosis; Triggering Receptor Expressed on Myeloid Cells-1

2019
[Rheumatoid arthritis: a cardiovascular disease?].
    Annales de cardiologie et d'angeiologie, 2012, Volume: 61, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Humans; Inflammation; Methotrexate; Risk Factors; Stroke; Tumor Necrosis Factor-alpha

2012

Trials

3 trial(s) available for methotrexate and Stroke

ArticleYear
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.
    The New England journal of medicine, 2019, 02-21, Volume: 380, Issue:8

    Topics: Aged; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Confidence Intervals; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Statistics, Nonparametric; Stroke; Transaminases

2019
Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:5

    Topics: Acute Kidney Injury; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Comparative Effectiveness Research; Cytarabine; Death, Sudden; Denmark; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Gastrointestinal Diseases; Germany; Heart Injuries; Hematopoietic Stem Cell Transplantation; Humans; Hyperglycemia; Induction Chemotherapy; Infections; Intraocular Lymphoma; Italy; Kaplan-Meier Estimate; Lymphoma, B-Cell; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Mucositis; Neurotoxicity Syndromes; Neutropenia; Optic Nerve Neoplasms; Poisoning; Radiotherapy, Adjuvant; Remission Induction; Rituximab; Stroke; Switzerland; Thiotepa; Thrombocytopenia; Thrombosis; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; United Kingdom

2016
MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.
    Neurology, 2006, May-09, Volume: 66, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Hematologic Diseases; Humans; Idarubicin; Life Tables; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Remission Induction; Stroke; Survival Analysis; Thiotepa

2006

Other Studies

26 other study(ies) available for methotrexate and Stroke

ArticleYear
[Methotrexate-induced stroke-like syndrome: A pediatric case report].
    Archivos argentinos de pediatria, 2021, Volume: 119, Issue:5

    Topics: Antimetabolites, Antineoplastic; Child; Humans; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2021
Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis.
    Seminars in arthritis and rheumatism, 2022, Volume: 56

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Humans; Methotrexate; Outcome Assessment, Health Care; Stroke

2022
Elderly patients with comorbidities in the definition of difficult-to-treat rheumatoid arthritis.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:11

    Topics: Abatacept; Age Factors; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Comorbidity; Drug Resistance; Female; Fractures, Bone; Glucocorticoids; Humans; Hypertension; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Myocardial Ischemia; Prednisolone; Renal Insufficiency, Chronic; Severity of Illness Index; Stroke; Tumor Necrosis Factor Inhibitors

2021
Investigating changes in disease activity as a mediator of cardiovascular risk reduction with methotrexate use in rheumatoid arthritis.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:11

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Coronary Artery Disease; Female; Heart Disease Risk Factors; Heart Failure; Hospitalization; Humans; Incidence; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Stroke

2021
Attenuation of Myeloid-Specific TGFβ Signaling Induces Inflammatory Cerebrovascular Disease and Stroke.
    Circulation research, 2017, Dec-08, Volume: 121, Issue:12

    Topics: Animals; Cell Line; Immunosuppressive Agents; Inflammation; Metformin; Methotrexate; Mice; Mice, Inbred C57BL; Myeloid Cells; NF-kappa B; Penetrance; Signal Transduction; Stroke; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2017
[Acute methotrexate-related neurotoxicity and pseudo-stroke syndrome].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:12

    Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Child; Diagnosis, Differential; Female; Humans; Leukoencephalopathies; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; Syndrome

2017
A Not Uncommon Cause of Stroke Mimicker in Children.
    Pediatric neurology, 2018, Volume: 80

    Topics: Adolescent; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2018
Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population-based retrospective cohort study.
    International journal of rheumatic diseases, 2018, Volume: 21, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Databases, Factual; Female; Humans; Hydroxychloroquine; Incidence; Male; Methotrexate; Middle Aged; Protective Factors; Retrospective Studies; Risk Factors; Stroke; Sulfasalazine; Taiwan; Treatment Outcome

2018
Subacute Methotrexate Encephalopathy Mimicking Ischemic Stroke With Dynamic Changes on Magnetic Resonance Imaging.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:11

    Topics: Adult; Antimetabolites, Antineoplastic; Brain Ischemia; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Dysarthria; Early Diagnosis; Encephalitis; Female; Humans; Lymphoma, B-Cell; Methotrexate; Paresis; Predictive Value of Tests; Stroke

2018
Characteristics of methotrexate-induced stroke-like neurotoxicity.
    International journal of hematology, 2018, Volume: 108, Issue:6

    Topics: Antimetabolites, Antineoplastic; Blood Coagulation; Blood Coagulation Tests; Child; Child, Preschool; Diagnosis, Differential; Female; Hematologic Neoplasms; Humans; Leukoencephalopathies; Male; Methotrexate; Neurotoxicity Syndromes; Retrospective Studies; Stroke

2018
Methotrexate-induced toxic leukoencephalopathy: an uncommon stroke mimic.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019, Volume: 40, Issue:6

    Topics: Antimetabolites, Antineoplastic; Brain; Diagnosis, Differential; Female; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Methotrexate; Stroke; Young Adult

2019
Multiple cerebral infarcts: a rare complication of neurosarcoidosis.
    Practical neurology, 2019, Volume: 19, Issue:3

    Topics: Adrenal Cortex Hormones; Central Nervous System Diseases; Cerebral Infarction; Humans; Hydrocephalus; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Sarcoidosis; Stroke

2019
Methotrexate: CIRTified for preventing atherosclerotic events?
    The journal of the Royal College of Physicians of Edinburgh, 2019, Volume: 49, Issue:2

    Topics: Antirheumatic Agents; Atherosclerosis; Hospitalization; Humans; Methotrexate; Myocardial Infarction; Stroke

2019
Cardiovascular risk in rheumatoid arthritis: comparing TNF-α blockade with nonbiologic DMARDs.
    The American journal of medicine, 2013, Volume: 126, Issue:8

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Cohort Studies; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Myocardial Infarction; Myocardial Revascularization; Proportional Hazards Models; Retrospective Studies; Risk; Stroke; Treatment Outcome; Tumor Necrosis Factor-alpha

2013
Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with severe psoriasis: 5-year follow-up of a Danish nationwide cohort.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Biological Products; Cardiovascular Diseases; Cause of Death; Climatotherapy; Cyclosporine; Denmark; Dermatologic Agents; Female; Follow-Up Studies; Humans; Incidence; Longitudinal Studies; Male; Methotrexate; Middle Aged; Myocardial Infarction; Phototherapy; Psoriasis; Registries; Retinoids; Severity of Illness Index; Stroke; Tumor Necrosis Factor-alpha; Ustekinumab

2015
Contrast-enhanced ultrasonography in Takayasu arteritis: watching and monitoring the arterial inflammation.
    BMJ case reports, 2015, Oct-09, Volume: 2015

    Topics: Adrenal Cortex Hormones; Adult; Carotid Artery, Common; Contrast Media; Disease Management; Humans; Male; Methotrexate; Stroke; Takayasu Arteritis; Tissue Plasminogen Activator; Ultrasonography

2015
Unilateral Gottron Papules in a Patient Following a Stroke: Clinical Insights Into the Disease Mechanisms and Pathophysiology of Cutaneous Dermatomyositis.
    JAMA dermatology, 2016, 09-01, Volume: 152, Issue:9

    Topics: Biopsy, Needle; Dermatomyositis; Drug Therapy, Combination; Female; Hand Dermatoses; Humans; Hydroxychloroquine; Immunohistochemistry; Methotrexate; Middle Aged; Stroke; Treatment Outcome

2016
Cardiovascular event risk assessment in psoriasis patients treated with tumor necrosis factor-α inhibitors versus methotrexate.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:1

    Topics: Adalimumab; Adolescent; Adult; Aged; Angina, Unstable; Cardiovascular Diseases; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Protective Factors; Psoriasis; Risk Assessment; Stroke; Time Factors; Tumor Necrosis Factor-alpha; Young Adult

2017
A Stroke Mimic: Methotrexate-induced Neurotoxicity in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:4

    Topics: Adolescent; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dextromethorphan; Emergency Service, Hospital; Excitatory Amino Acid Antagonists; Facial Paralysis; Female; Humans; Lower Extremity; Methotrexate; Muscle Hypotonia; Muscle Weakness; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; Upper Extremity

2017
A Stroke Mimic: A 14-Year-Old Cancer Patient Presenting With Acute Right-Sided Weakness.
    Pediatric emergency care, 2017, Volume: 33, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Diagnosis, Differential; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Paresis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2017
Hyperperfusion on magnetic resonance imaging in acute chemotherapy-related leukoencephalopathy.
    Journal of child neurology, 2010, Volume: 25, Issue:6

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Diagnosis, Differential; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; Vincristine

2010
Transient leukoencephalopathy after intrathecal methotrexate mimicking stroke.
    Emergency radiology, 2011, Volume: 18, Issue:4

    Topics: Adolescent; Antimetabolites, Antineoplastic; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Humans; Injections, Spinal; Leukoencephalopathies; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2011
Methotrexate leukoencephalopathy mimics acute progressive stroke.
    Journal of neurology, 2011, Volume: 258, Issue:11

    Topics: Adolescent; Antimetabolites, Antineoplastic; Diagnosis, Differential; Humans; Leukoencephalopathies; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2011
'Stroke-like syndrome' caused by intrathecal methotrexate in patients treated during the UKALL 2003 trial.
    Leukemia, 2013, Volume: 27, Issue:4

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Female; Humans; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; United Kingdom

2013
Heart risks of RA drugs compared. Biologics confer same risk as old-fashioned methotrexate; cytotoxic drugs increase cardiac risk.
    DukeMedicine healthnews, 2007, Volume: 13, Issue:3

    Topics: Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Methotrexate; Myocardial Infarction; Stroke

2007
Delayed leukoencephalopathy with stroke-like presentation in chemotherapy recipients.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain; Brain Edema; Capecitabine; Dementia, Vascular; Deoxycytidine; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Female; Fluorouracil; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasms; Nerve Fibers, Myelinated; Neurologic Examination; Registries; Remission, Spontaneous; Stroke; Tegafur

2008