Page last updated: 2024-08-25

methotrexate and Sclerosis, Systemic

methotrexate has been researched along with Sclerosis, Systemic in 98 studies

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199014 (14.29)18.7374
1990's13 (13.27)18.2507
2000's30 (30.61)29.6817
2010's29 (29.59)24.3611
2020's12 (12.24)2.80

Authors

AuthorsStudies
Cao, L; Cheng, Y; Jiang, Z; Lin, C; Ren, G; Shen, J; Shen, Y; Wan, W; Xu, W; Zhu, X; Zou, H1
Kayser, C; Victória de Oliveira Martins, L1
Damjanov, N; Jelovac, M; Kotur, N; Pavlovic, D; Pavlovic, S; Ristivojevic, B; Spasovski, V; Zukic, B1
De, D; Handa, S; Kaushik, A; Mahajan, R1
Tirelli, F; Zulian, F1
Assassi, S; Bernstein, EJ; Castelino, FV; Clements, PJ; Domsic, RT; Elashoff, RM; Frech, T; Furst, DE; Goldin, J; Gordon, JK; Hant, FN; Hinchcliff, M; Khanna, D; Li, N; Mayes, MD; Roth, MD; Rünger, D; Shah, AA; Shanmugam, VK; Steen, VD; Tashkin, DP; Volkmann, ER; Ying, J1
Buckley, M; Ede, KC; Edelheit, B; Ishaq, SS; Li, SC; Liu, C; Rabinovich, CE; Torok, KS1
Wells, AU1
Hudowenz, O; Klemm, P; Lange, U; Mueller-Ladner, U1
Batalov, AZ; Batalov, ZA; Karalilova, RV; Matucci-Cerinic, M; Sapundzhieva, TL1
Arida, A; Bournia, VK; Panopoulos, ST; Sfikakis, PP; Tektonidou, MG1
Béhal, H; Duhamel, A; Faivre, JB; Hachulla, AL; Hachulla, E; Hatron, PY; Lambert, M; Launay, D; Le Gouellec, N; Matran, R; Morell-Dubois, S; Perez, T; Remy-Jardin, M; Sobanski, V1
Cutolo, M; Paolino, S; Pizzorni, C; Ruaro, B; Sulli, A1
Adler, S; Allanore, Y; Czirják, L; DelGaldo, F; Denton, CP; Distler, O; Frerix, M; Huscher, D; Matucci-Cerinic, M; Mueller-Ladner, U; Riemekasten, G; Siegert, E; Tarner, IH; Valentini, G; Villiger, PM; Walker, UA1
Zulian, F1
Fernández-Codina, A; Pope, JE; Walker, KM1
Bershow, A; Crowson, AN; Lee, KR1
Pan, L; Wang, Q; Xia, JX; Yang, QR; Zheng, JN; Zhu, GQ1
Andrews, T; Becker, ML; Dedeoglu, F; Feldman, BM; Ferguson, PJ; Fuhlbrigge, RC; Higgins, GC; Hong, S; Ibarra, MF; Laxer, RM; Li, SC; Mason, T; Pope, E; Punaro, M; Rabinovich, CE; Stewart, K; Torok, KS1
Abdo, MS; Gaber, SM; Mohammed, RH; Raslan, HM1
Cuffaro, G; Sperotto, F; Zulian, F1
Ishikawa, O; Motegi, S1
Foeldvari, I1
Bellando-Randone, S; Cappelli, S; Guiducci, S; Matucci-Cerinic, M1
Akiyama, M; Muro, Y; Sugiura, K; Tanahashi, K1
Feld, J; Shupak, A; Zisman, D1
Furst, DE; Volkmann, ER1
Bi, XD; Bian, H; Han, L; Hu, JL; Mao, BY; Yuan, M1
Brusselle, G; Cutolo, M; DE Keyser, F; DE Pauw, M; Decuman, S; Deschepper, E; Melsens, K; Piette, Y; Pizzorni, C; Riccieri, V; Ruaro, B; Smith, V; Sulli, A; Vandecasteele, E1
Rajapakse, C1
Cerinic, MM; Valentini, G1
Afsar, FS; Christen-Zaech, S; Hakim, MD; Paller, AS1
Rudnicka, L; Sicińska, J1
Lee, P; Low, AH1
Feldman, BM; Johnson, SR; Pope, JE; Tomlinson, GA1
Bournia, VK; Gershwin, ME; Moutsopoulos, HM; Selmi, C; Vlachoyiannopoulos, PG1
Dwyer, N; Jones, G; Kilpatrick, D1
Enk, A; Gholam, P; Hartmann, M; Sehr, T1
Denton, CP; Quillinan, NP1
Wimmersberger, Y; Zuercher, D1
Isik, A; Koca, SS; Ozercan, IH; Ozgen, M1
de Souza, CB; Ferriani, VP; Pileggi, GS1
Olesińska, M; Wiesik-Szewczyk, E1
Bau, V; Gahr, M; Hammermann, J; Hedrich, CM; Leszczynska, A1
Pope, J; Walker, KM1
Choi, YJ; Kim, HO; Kim, HS; Lee, JY; Park, YM1
Gutmacher, Z; Levin, L; Teich, S; Zigdon, H1
Baszis, K; Becker, M; Campillo, S; Cartwright, V; Cidon, M; Dedeoglu, F; Ferguson, PJ; Fuhlbrigge, RC; Higgins, GC; Hong, S; Ilowite, NT; Inman, CJ; Jacobe, HT; Jerath, R; Lasky, A; Laxer, RM; Li, SC; O'Neil, KM; Pope, E; Rabinovich, CE; Torok, KS; Vora, S; Wallace, CA; Zeft, A1
Beyer, C; Dees, C; Distler, A; Distler, JH; Distler, O; Gelse, K; Khodzhigorova, A; Lang, V; Schett, G; Schneider, H1
Lebeaux, D; Sène, D1
Alonso, S; Alperi, M; Arboleya, L; Fernández-Serna, M; Queiro, R1
Acar, P; Bodemer, C; Bonnet, D; Fournet, JC; Le Bidois, J; Ouachée-Chardin, M; Prieur, AM; Quartier, P1
Athreya, BH1
Lehman, TJ; Rosenkranz, ME1
Meissner, T1
Chwalińska-Sadowska, H; Mielnik, P; Prochorec-Sobieszek, M; Wagner, T1
Alam, MR; Das, SN; Haq, SA; Islam, N; Khan, GK; Rahim, A; Rahman, MH; Rahman, S; Sutradhar, SR1
Bargagli, E; Bellisai, F; Galeazzi, M; Rottoli, P; Volterrani, L1
Cozzi, F; Favaro, M; Marotta, H; Ostuni, PA; Sfriso, P; Todesco, S1
Furst, DE; Georges, GE; Henstorf, G; Langston, AA; Lee, J; McSweeney, PA; Nash, RA; Nelson, JL; Shulman, H; Storb, R; Sullivan, KM; Wener, M1
van den Hoogen, FH2
Kapoor, A; Khaitan, BK; Krishna Sumanth, M; Sharma, VK; Tejasvi, T1
Szekanecz, Z; Tamási, L1
Barry, J; Moktar, A; Murphy, GM; Ridge, CA1
Alkassab, F1
Baron, M; Bellamy, N; Campbell, J; Carette, S; Chalmers, I; Dales, P; Hanly, J; Kaminska, EA; Lee, P; Pope, JE1
Boerbooms, AM; van de Putte, LB; van den Berg, WB; van den Hoogen, FH; van der Kraan, PM; van Lier, HJ1
Boerbooms, AM; Rasker, JJ; Swaak, AJ; van de Putte, LB; van den Hoogen, FH; van Lier, HJ1
Senécal, JL; Uthman, I; Vázquez-Abad, D1
Cabral, D; Malleson, PN; Ortiz-Alvarez, O; Petty, RE; Prendiville, JS; Stringer, D1
Wilke, WS1
de Boo, T; de Jong, EM; Seyger, MM; van den Hoogen, FH1
Cunningham, BB; Vierra, E1
de Jong, EM; Seyger, MM; van de Kerkhof, PC; van den Hoogen, FH; van Vlijmen-Willems, IM1
Baron, M; Bellamy, N; Carette, S; Catoggio, L; Chalmers, IM; Ellman, M; Furst, DE; Hong, P; Kaminska, E; Markland, J; O'Hanlon, D; Pope, JE; Seibold, JR; Sibley, J; Smith, CD1
Carrier, S; Chen, TY; Zahran, AR1
Steen, VD1
Varga, J1
Lehman, TJ1
Ruszczak, Z1
Schulze, P1
Wigley, FM1
Boerbooms, AM; Rasker, JJ; van de Putte, LB; van den Hoogen, FH; van Venrooij, WJ1
Gross, WL; Reinhold-Keller, E; Schnabel, A; Wolff, HH1
Medsger, TA1
Boerbooms, AM; van de Putte, LB; van den Hoogen, FH1
Paulus, HE1
Moeschlin, S1
Schwartz, RS; Skinner, MD1
Barrière, H; Grolleau, JY; Welin, J1
Kerl, H; Klein, G; Sandhofer, M1
Arnett, FC; Stevens, MB; Whelton, JC; Zizic, TM1
Górkiewicz, A; Kostanecki, W; Mazurkiewicz, W; Zborzil, J1
Romiti, N1
Schuppli, R2
Civatte, J; Clauvel, JP; Danon, F; Degos, R1

Reviews

27 review(s) available for methotrexate and Sclerosis, Systemic

ArticleYear
Treatment of Inflammatory Arthritis in Systemic Sclerosis.
    Rheumatic diseases clinics of North America, 2023, Volume: 49, Issue:2

    Topics: Arthralgia; Arthritis, Rheumatoid; Humans; Methotrexate; Quality of Life; Scleroderma, Systemic

2023
Paediatric morphoea: a holistic review. Part 2: diagnosis, measures of disease activity, management and natural history.
    Clinical and experimental dermatology, 2020, Volume: 45, Issue:6

    Topics: Adrenal Cortex Hormones; Biomarkers; Child; Humans; Methotrexate; Mycophenolic Acid; Phototherapy; Scleroderma, Localized; Scleroderma, Systemic

2020
Treatment in Juvenile Scleroderma.
    Current rheumatology reports, 2020, 06-26, Volume: 22, Issue:8

    Topics: Child; Humans; Methotrexate; Mycophenolic Acid; Scleroderma, Localized; Scleroderma, Systemic

2020
Scleroderma in children.
    Best practice & research. Clinical rheumatology, 2017, Volume: 31, Issue:4

    Topics: Child; Decision Making; Humans; Immunosuppressive Agents; Male; Methotrexate; Scleroderma, Localized; Scleroderma, Systemic

2017
Scleroderma in children: an update.
    Current opinion in rheumatology, 2013, Volume: 25, Issue:5

    Topics: Child; Early Diagnosis; Humans; Immunosuppressive Agents; Methotrexate; Scleroderma, Localized; Scleroderma, Systemic; Treatment Outcome

2013
New developments in juvenile systemic and localized scleroderma.
    Rheumatic diseases clinics of North America, 2013, Volume: 39, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Child; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Microscopic Angioscopy; Mycophenolic Acid; Scleroderma, Localized; Scleroderma, Systemic; Skin; Thermography; Tomography, Optical Coherence; Ultrasonography, Doppler; Uveitis

2013
Is immunosuppressive therapy the anchor treatment to achieve remission in systemic sclerosis?
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:6

    Topics: Azathioprine; Biological Products; Cyclophosphamide; Humans; Immunosuppressive Agents; Methotrexate; Mycophenolic Acid; Remission Induction; Scleroderma, Systemic

2014
Management of Systemic Sclerosis-Related Skin Disease: A Review of Existing and Experimental Therapeutic Approaches.
    Rheumatic diseases clinics of North America, 2015, Volume: 41, Issue:3

    Topics: Animals; Cyclophosphamide; Diagnosis, Differential; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Raynaud Disease; Scleroderma, Systemic; Treatment Failure

2015
Anti-inflammatory: new trends in the treatment of the patient with systemic sclerosis.
    Expert opinion on emerging drugs, 2008, Volume: 13, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Cyclophosphamide; Endothelin A Receptor Antagonists; Europe; Humans; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Scleroderma, Systemic

2008
[Current treatment of systemic sclerosis. Part I. Immunosuppressive treatment].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2008, Volume: 25, Issue:146

    Topics: Adrenal Cortex Hormones; Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Cytostatic Agents; Humans; Immunosuppressive Agents; Methotrexate; Musculoskeletal Diseases; Mycophenolic Acid; Scleroderma, Systemic

2008
Recent advances in the treatment of systemic sclerosis.
    Clinical reviews in allergy & immunology, 2009, Volume: 36, Issue:2-3

    Topics: Animals; Calcium Channel Blockers; Cell Differentiation; Clinical Trials as Topic; Cyclophosphamide; Fibroblasts; Fibrosis; Humans; Immunosuppressive Agents; Methotrexate; Scleroderma, Systemic; Signal Transduction; Vasodilator Agents; Ventricular Remodeling

2009
Disease-modifying treatment in systemic sclerosis: current status.
    Current opinion in rheumatology, 2009, Volume: 21, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Autoantigens; Azathioprine; Collagen Type I; Connective Tissue Growth Factor; Cyclophosphamide; Evidence-Based Practice; Fibrosis; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Methotrexate; Mycophenolic Acid; Plasmapheresis; Rituximab; Scleroderma, Systemic; Transforming Growth Factor beta; Transplantation, Autologous; Tumor Necrosis Factor-alpha

2009
[Management of patients with systemic sclerosis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010, Volume: 28, Issue:167

    Topics: Bone Marrow Transplantation; Cyclophosphamide; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Kidney Diseases; Lung Diseases, Interstitial; Methotrexate; Prognosis; Quality of Life; Raynaud Disease; Scleroderma, Systemic; Stem Cell Transplantation; Treatment Outcome

2010
Eosinophilic fasciitis (Shulman disease).
    Best practice & research. Clinical rheumatology, 2012, Volume: 26, Issue:4

    Topics: Adrenal Cortex Hormones; Churg-Strauss Syndrome; Diagnosis, Differential; Edema; Eosinophilia; Eosinophilia-Myalgia Syndrome; Fasciitis; Humans; Magnetic Resonance Imaging; Methotrexate; Rare Diseases; Scleroderma, Localized; Scleroderma, Systemic; Skin Diseases

2012
Dropped head syndrome in a patient with scleromyositis.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2013, Volume: 19, Issue:1

    Topics: Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Muscle Weakness; Myositis; Neck Muscles; Prednisone; Scleroderma, Systemic; Syndrome; Treatment Outcome

2013
Juvenile scleroderma.
    Current opinion in rheumatology, 2002, Volume: 14, Issue:5

    Topics: Adjuvants, Immunologic; Antirheumatic Agents; Child; Drug Therapy, Combination; Humans; Methotrexate; Scleroderma, Systemic; Vasodilator Agents

2002
[Treatment of systemic sclerosis].
    Zeitschrift fur Rheumatologie, 2006, Volume: 65, Issue:4

    Topics: Cyclophosphamide; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Hematopoietic Stem Cell Transplantation; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Methotrexate; Penicillamine; Randomized Controlled Trials as Topic; Scleroderma, Systemic; Vasodilator Agents

2006
[Biological therapy of arthritis and systemic autoimmune diseases].
    Orvosi hetilap, 2007, Apr-08, Volume: 148 Suppl 1

    Topics: Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Autoimmune Diseases; B-Lymphocytes; Biological Therapy; Dermatomyositis; Humans; Lupus Erythematosus, Systemic; Methotrexate; Polymyositis; Scleroderma, Systemic; Sjogren's Syndrome; Spondylitis, Ankylosing; T-Lymphocytes; Tumor Necrosis Factor-alpha

2007
Methotrexate use in miscellaneous inflammatory diseases.
    Rheumatic diseases clinics of North America, 1997, Volume: 23, Issue:4

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Connective Tissue Diseases; Humans; Inflammation; Lupus Erythematosus, Systemic; Methotrexate; Myositis; Sarcoidosis; Scleroderma, Systemic; Still's Disease, Adult-Onset

1997
Therapeutic interventions in systemic sclerosis.
    The Netherlands journal of medicine, 1998, Volume: 53, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Clinical Trials as Topic; Cyclophosphamide; Humans; Methotrexate; Netherlands; Scleroderma, Systemic; Survival Rate; Treatment Outcome

1998
Morphea and localized scleroderma in children.
    Seminars in cutaneous medicine and surgery, 1999, Volume: 18, Issue:3

    Topics: Adrenal Cortex Hormones; Biomarkers; Calcitriol; Child; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Scleroderma, Localized; Scleroderma, Systemic; Skin; Ultraviolet Therapy

1999
Treatment of systemic sclerosis.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:5

    Topics: Antirheumatic Agents; Cyclosporine; Drug Therapy, Combination; Humans; Interferons; Methotrexate; Middle Aged; Raynaud Disease; Scleroderma, Systemic

2001
[Immunosuppressive agents for therapy of autoimmune diseases of the skin and of psoriasis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1977, Volume: 28, Issue:3

    Topics: Autoimmune Diseases; Dermatitis Herpetiformis; Dermatomyositis; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Pemphigus; Polyarteritis Nodosa; Psoriasis; Pyoderma; Scleroderma, Systemic; Skin Diseases

1977
[Indications and limits of long-term therapy with immunosuppressive (and cytostatic) agents in various chronic skin diseases].
    Zeitschrift fur arztliche Fortbildung, 1977, Jun-15, Volume: 71, Issue:12

    Topics: Arthritis, Reactive; Azathioprine; Chronic Disease; Cyclophosphamide; Dermatomyositis; Humans; Immunosuppressive Agents; Impetigo; Long-Term Care; Lupus Erythematosus, Discoid; Methotrexate; Pemphigus; Penicillamine; Polyarteritis Nodosa; Prednisolone; Psoriasis; Pyoderma; Scleroderma, Systemic; Skin Diseases; Wissler's Syndrome

1977
Treatment of systemic sclerosis.
    Current opinion in rheumatology, 1992, Volume: 4, Issue:6

    Topics: Cyclosporine; Humans; Methotrexate; Penicillamine; Photochemotherapy; Raynaud Disease; Scleroderma, Systemic

1992
Treatment of systemic sclerosis.
    Current opinion in rheumatology, 1990, Volume: 2, Issue:6

    Topics: Humans; Interferon-gamma; Methotrexate; Retinoids; Scleroderma, Systemic

1990
Immunosuppressive therapy. 1.
    The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5

    Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic

1972

Trials

12 trial(s) available for methotrexate and Sclerosis, Systemic

ArticleYear
Tofacitinib in the treatment of skin and musculoskeletal involvement in patients with systemic sclerosis, evaluated by ultrasound.
    Rheumatology international, 2021, Volume: 41, Issue:10

    Topics: Adult; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pilot Projects; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Scleroderma, Systemic; Severity of Illness Index; Skin; Skin Ulcer; Ultrasonography

2021
[Effect of Wenyang Huazhuo Tongluo Recipe on Peripheral Blood Thl7/Treg Cell Balance in Systemic Sclerosis Patients].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:8

    Topics: Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Interleukin-10; Interleukin-17; Methotrexate; Peptide Fragments; Procollagen; Scleroderma, Systemic; T-Lymphocytes, Regulatory; Th17 Cells

2015
Shifting our thinking about uncommon disease trials: the case of methotrexate in scleroderma.
    The Journal of rheumatology, 2009, Volume: 36, Issue:2

    Topics: Adult; Antirheumatic Agents; Bayes Theorem; Clinical Trials as Topic; Data Interpretation, Statistical; Double-Blind Method; Humans; Methotrexate; Outcome Assessment, Health Care; Placebos; Rare Diseases; Reproducibility of Results; Scleroderma, Systemic; Skin Diseases; Treatment Outcome

2009
Safety and immunogenicity of varicella vaccine in patients with juvenile rheumatic diseases receiving methotrexate and corticosteroids.
    Arthritis care & research, 2010, Volume: 62, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Arthritis, Juvenile; Chickenpox Vaccine; Child; Child, Preschool; Dermatomyositis; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Injections, Subcutaneous; Male; Methotrexate; Scleroderma, Systemic; Vaccines, Attenuated; Young Adult

2010
Placebo controlled trial of methotrexate in systemic sclerosis.
    Mymensingh medical journal : MMJ, 2005, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Antirheumatic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Respiratory Function Tests; Scleroderma, Systemic; Statistics, Nonparametric; Treatment Outcome

2005
Evaluation of oral methotrexate in the treatment of systemic sclerosis.
    International journal of dermatology, 2007, Volume: 46, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Immunosuppressive Agents; India; Male; Methotrexate; Middle Aged; Scleroderma, Systemic; Treatment Outcome

2007
Variability of skin scores and clinical measurements in scleroderma.
    The Journal of rheumatology, 1995, Volume: 22, Issue:7

    Topics: Female; Humans; Male; Methotrexate; Middle Aged; Observer Variation; Reproducibility of Results; Scleroderma, Systemic; Skin; Treatment Outcome

1995
Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial.
    British journal of rheumatology, 1996, Volume: 35, Issue:4

    Topics: Adult; Aged; Antirheumatic Agents; Double-Blind Method; Female; Humans; Male; Methotrexate; Middle Aged; Scleroderma, Systemic; Severity of Illness Index; Time Factors; Treatment Outcome

1996
Low-dose methotrexate in the treatment of widespread morphea.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:2 Pt 1

    Topics: Adult; Aged; Biomarkers; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Prospective Studies; Scleroderma, Systemic; Skin; Statistics, Nonparametric; Time Factors

1998
A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:6

    Topics: Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Health Status; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Scleroderma, Systemic; Severity of Illness Index; Skin; Surveys and Questionnaires; Treatment Outcome

2001
Methotrexate shows marginal clinical efficiency in early scleroderma.
    Current rheumatology reports, 2002, Volume: 4, Issue:2

    Topics: Double-Blind Method; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Prospective Studies; Scleroderma, Systemic

2002
Immunosuppressive therapy. 1.
    The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5

    Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic

1972

Other Studies

60 other study(ies) available for methotrexate and Sclerosis, Systemic

ArticleYear
Spontaneous tendon rupture in a patient with systemic sclerosis: a case report.
    BMC musculoskeletal disorders, 2022, Nov-22, Volume: 23, Issue:1

    Topics: Female; Humans; Methotrexate; Middle Aged; Rupture, Spontaneous; Scleroderma, Systemic; Tendon Injuries; Tendons; Tenosynovitis

2022
Can Pharmacogenetic Variants in
    International journal of molecular sciences, 2023, May-10, Volume: 24, Issue:10

    Topics: Azathioprine; Genotype; Humans; Liver-Specific Organic Anion Transporter 1; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Scleroderma, Systemic

2023
Predictive Significance of Serum Interferon-Inducible Protein Score for Response to Treatment in Systemic Sclerosis-Related Interstitial Lung Disease.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:6

    Topics: Adult; Aged; beta 2-Microglobulin; Chemokine CCL19; Chemokine CCL8; Chemokine CXCL10; Chemokine CXCL9; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Observational Studies as Topic; Prognosis; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor, Type II; Scleroderma, Systemic; Vital Capacity

2021
Preliminary evidence on abatacept safety and efficacy in refractory juvenile localized scleroderma.
    Rheumatology (Oxford, England), 2021, 08-02, Volume: 60, Issue:8

    Topics: Abatacept; Adolescent; Antirheumatic Agents; Child; Cohort Studies; Female; Humans; Male; Methotrexate; Mycophenolic Acid; Retrospective Studies; Scleroderma, Localized; Scleroderma, Systemic; Treatment Failure; Treatment Outcome

2021
New insights into the treatment of CTD-ILD.
    Nature reviews. Rheumatology, 2021, Volume: 17, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Connective Tissue Diseases; Disease Progression; Humans; Indoles; Interleukin-6; Lung Diseases, Interstitial; Methotrexate; Prevalence; Protein Kinase Inhibitors; Pulmonary Fibrosis; Randomized Controlled Trials as Topic; Scleroderma, Systemic; Vital Capacity

2021
Widespread soft tissue calcification in systemic sclerosis, polymyositis, and polyarthritis.
    Lancet (London, England), 2021, 01-30, Volume: 397, Issue:10272

    Topics: Arthritis; Azetidines; Female; Humans; Immunoglobulins; Immunosuppressive Agents; Methotrexate; Middle Aged; Polymyositis; Purines; Pyrazoles; Scleroderma, Systemic; Sulfonamides

2021
Anti-interleukin 6 Therapy Effect for Refractory Joint and Skin Involvement in Systemic Sclerosis: A Real-world, Single-center Experience.
    The Journal of rheumatology, 2022, Volume: 49, Issue:1

    Topics: Adult; Antirheumatic Agents; Female; Humans; Interleukin-6; Methotrexate; Middle Aged; Rituximab; Scleroderma, Systemic; Treatment Outcome

2022
Predictors of lung function test severity and outcome in systemic sclerosis-associated interstitial lung disease.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbon Monoxide; Cyclophosphamide; Diffusion; Echocardiography; Female; Fingers; Follow-Up Studies; Humans; Hypertension, Pulmonary; Linear Models; Lung; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Pulmonary Diffusing Capacity; Respiratory Function Tests; Scleroderma, Systemic; Ulcer; Young Adult

2017
Assessment of treatment effects on digital ulcer and blood perfusion by laser speckle contrast analysis in a patient affected by systemic sclerosis.
    Reumatismo, 2017, Sep-21, Volume: 69, Issue:3

    Topics: Bosentan; Female; Fingers; Humans; Iloprost; Lasers; Methotrexate; Microcirculation; Microscopic Angioscopy; Middle Aged; para-Aminobenzoates; Raynaud Disease; Scattering, Radiation; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Tramadol; Treatment Outcome

2017
Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group.
    Arthritis research & therapy, 2018, 01-30, Volume: 20, Issue:1

    Topics: Adult; Aged; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Lung; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Precision Medicine; Respiratory Function Tests; Scleroderma, Systemic

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Calcium Channels; Cyclophosphamide; Endothelin Receptor Antagonists; Glucocorticoids; Humans; Hydroxychloroquine; Hypertension, Pulmonary; Immunosuppressive Agents; Kidney Diseases; Lung Diseases, Interstitial; Methotrexate; Mycophenolic Acid; Phosphodiesterase 5 Inhibitors; Prostaglandins; Raynaud Disease; Rituximab; Scleroderma, Systemic

2018
Elephantiasis nostras verrucosa secondary to scleroderma.
    Cutis, 2019, Volume: 103, Issue:2

    Topics: Anti-Bacterial Agents; Bandages; Biopsy; Cephalexin; Dermatologic Agents; Doxepin; Elephantiasis; Female; Humans; Methotrexate; Middle Aged; Mupirocin; Mycophenolic Acid; PUVA Therapy; Scleroderma, Systemic; Skin; Skin Cream; Terfenadine; Treatment Outcome

2019
Comparative efficacy and safety of immunosuppressive therapies for systemic sclerosis related interstitial lung disease: A Bayesian network analysis.
    Modern rheumatology, 2020, Volume: 30, Issue:4

    Topics: Adult; Azathioprine; Bayes Theorem; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Scleroderma, Systemic; Treatment Outcome; Vital Capacity

2020
Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study.
    Pediatric rheumatology online journal, 2019, Jul-15, Volume: 17, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Antirheumatic Agents; Child; Comparative Effectiveness Research; Drug Therapy, Combination; Feasibility Studies; Female; Glucocorticoids; Humans; Male; Methotrexate; Methylprednisolone; Pilot Projects; Prednisone; Prospective Studies; Rare Diseases; Scleroderma, Localized; Scleroderma, Systemic; Young Adult

2019
Serum B-cell activating factor assessment in a population of Egyptian patients with systemic sclerosis.
    International journal of rheumatic diseases, 2013, Volume: 16, Issue:2

    Topics: Adolescent; Adult; B-Cell Activating Factor; Biomarkers; Case-Control Studies; Chi-Square Distribution; Cross-Sectional Studies; Egypt; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Intestinal Pseudo-Obstruction; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Scleroderma, Systemic; Severity of Illness Index; Up-Regulation; Young Adult

2013
Methotrexate-induced accelerated nodulosis in a patient with rheumatoid arthritis and scleroderma.
    Acta dermato-venereologica, 2014, Volume: 94, Issue:3

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Rheumatoid Nodule; Risk Factors; Scleroderma, Systemic; Time Factors

2014
Disappearance of circulating autoantibodies to RNA polymerase III in a patient with systemic sclerosis successfully treated with corticosteroid and methotrexate.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:7

    Topics: Aged; Autoantibodies; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; RNA Polymerase III; Scleroderma, Systemic

2015
Diffuse systemic sclerosis presenting as Meniere's disease-like symptoms as part of autoimmune inner ear disease.
    The Israel Medical Association journal : IMAJ, 2015, Volume: 17, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arrhythmias, Cardiac; Diagnosis, Differential; Disease Progression; Fatal Outcome; Female; Hearing Loss, Sensorineural; Humans; Labyrinth Diseases; Meniere Disease; Methotrexate; Monitoring, Immunologic; Prednisone; Scleroderma, Systemic

2015
Stabilization of Microcirculation in Patients with Early Systemic Sclerosis with Diffuse Skin Involvement following Rituximab Treatment: An Open-label Study.
    The Journal of rheumatology, 2016, Volume: 43, Issue:5

    Topics: Adult; Female; Humans; Immunologic Factors; Immunosuppressive Agents; Male; Methotrexate; Microcirculation; Microvessels; Middle Aged; Nails; Pilot Projects; Rituximab; Scleroderma, Systemic

2016
Pharyngoesophageal dysphagia: an under recognised, potentially fatal, but very treatable feature of systemic sclerosis.
    Internal medicine journal, 2016, Volume: 46, Issue:11

    Topics: Aged; Deglutition Disorders; Endoscopy, Gastrointestinal; Female; Fluoroscopy; Humans; Male; Methotrexate; Middle Aged; Prednisone; Scleroderma, Systemic

2016
Pediatric morphea (localized scleroderma): review of 136 patients.
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:3

    Topics: Adolescent; Age of Onset; Antibodies, Antinuclear; Autoimmune Diseases; Child; Child, Preschool; Dermatologic Agents; Female; Humans; Infant; Male; Methotrexate; Prevalence; Retrospective Studies; Risk Factors; Scleroderma, Localized; Scleroderma, Systemic; Sex Factors; Skin; White People

2008
Indirect evidence for the efficacy of methotrexate in diffuse systemic sclerosis.
    The Journal of rheumatology, 2008, Volume: 35, Issue:11

    Topics: Adult; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Scleroderma, Systemic

2008
Severe hepatotoxicity in a patient on bosentan upon addition of methotrexate: reversible with resumption of methotrexate without bosentan.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:2

    Topics: Antihypertensive Agents; Bosentan; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Drug Interactions; Female; Humans; Hypertension, Pulmonary; Methotrexate; Middle Aged; Polypharmacy; Scleroderma, Systemic; Sulfonamides

2009
Successful treatment of systemic-sclerosis-related digital ulcers with a selective endothelin type A receptor antagonist (sitaxentan).
    Dermatology (Basel, Switzerland), 2009, Volume: 219, Issue:2

    Topics: Adult; Amlodipine; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Female; Fingers; Follow-Up Studies; Hand Dermatoses; Humans; Methotrexate; Receptor, Endothelin A; Risk Assessment; Scleroderma, Systemic; Severity of Illness Index; Skin Ulcer; Treatment Outcome

2009
Graves' disease associated with primary systemic sclerosis.
    Orbit (Amsterdam, Netherlands), 2009, Volume: 28, Issue:4

    Topics: Azathioprine; Bosentan; Cyclophosphamide; Drug Therapy, Combination; Female; Glucocorticoids; Graves Disease; Humans; Hypertension, Pulmonary; Immunoglobulins, Intravenous; Immunosuppressive Agents; Methotrexate; Middle Aged; Mycophenolic Acid; Proteinuria; Raynaud Disease; Scleroderma, Systemic; Sulfonamides

2009
Methotrexate has no antifibrotic effect in bleomycin-induced experimental scleroderma.
    The Journal of rheumatology, 2010, Volume: 37, Issue:3

    Topics: Animals; Antirheumatic Agents; Bleomycin; Disease Models, Animal; Fibrosis; Injections, Intraperitoneal; Methotrexate; Mice; Mice, Inbred BALB C; Scleroderma, Systemic; Skin; Treatment Outcome

2010
Chorioretinitis in a 7-year-old African girl, probably related to JSSc resolving to methotrexate therapy.
    Klinische Padiatrie, 2011, Volume: 223, Issue:2

    Topics: Child; Chorioretinitis; Diagnosis, Differential; Female; Germany; Humans; Immunosuppressive Agents; Methotrexate; Ophthalmoscopes; Scleroderma, Systemic; Visual Acuity

2011
Expert agreement on EULAR/EUSTAR recommendations for the management of systemic sclerosis.
    The Journal of rheumatology, 2011, Volume: 38, Issue:7

    Topics: Bosentan; Canada; Epoprostenol; Europe; Health Surveys; Humans; Hypertension, Pulmonary; Iloprost; Methotrexate; North America; Practice Guidelines as Topic; Scleroderma, Systemic; Skin Diseases; Societies, Medical; Sulfonamides; Treatment Outcome; Vascular Diseases

2011
Case of juvenile localized scleroderma with joint sclerosis and Sjögren's syndrome in a child with precocious puberty.
    The Journal of dermatology, 2011, Volume: 38, Issue:10

    Topics: Child; Female; Humans; Joint Diseases; Methotrexate; Methylprednisolone; Puberty, Precocious; Scleroderma, Localized; Scleroderma, Systemic; Sclerosis; Sjogren's Syndrome; Triptorelin Pamoate

2011
Full-mouth rehabilitation using dental implants in a patient with scleroderma.
    Quintessence international (Berlin, Germany : 1985), 2011, Volume: 42, Issue:9

    Topics: Alveolar Bone Loss; Dental Caries; Dental Implantation, Endosseous; Dental Implants; Dental Prosthesis, Implant-Supported; Denture Design; Denture, Complete; Esthetics, Dental; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Mouth Rehabilitation; Oral Hygiene; Periodontal Diseases; Scleroderma, Systemic; Steroids; Tooth Extraction

2011
Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma.
    Arthritis care & research, 2012, Volume: 64, Issue:8

    Topics: Adolescent; Consensus; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Methylprednisolone; Practice Guidelines as Topic; Program Development; Randomized Controlled Trials as Topic; Scleroderma, Localized; Scleroderma, Systemic; Treatment Outcome; Young Adult

2012
Inhibition of sumoylation prevents experimental fibrosis.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:11

    Topics: Adolescent; Adult; Animals; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Humans; Immunosuppressive Agents; Keratinocytes; Male; Methotrexate; Mice; Middle Aged; Receptors, Transforming Growth Factor beta; RNA, Small Interfering; Scleroderma, Systemic; Signal Transduction; Skin; Smad3 Protein; SUMO-1 Protein; Sumoylation; Ubiquitin-Conjugating Enzymes; Young Adult

2012
Severe cardiac involvement in children with systemic sclerosis and myositis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:8

    Topics: Adolescent; Cardiomyopathies; Child; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Male; Methotrexate; Polymyositis; Prednisone; Scleroderma, Systemic; Survival Rate; Treatment Outcome

2002
Clinical trials for pediatric scleroderma.
    Current rheumatology reports, 2002, Volume: 4, Issue:6

    Topics: Antirheumatic Agents; Child; Clinical Trials as Topic; Cyclophosphamide; Humans; Methotrexate; Penicillamine; Scleroderma, Systemic

2002
[New strategies against autoaggressive immune system. Is rheumatism to be healable soon?].
    MMW Fortschritte der Medizin, 2003, Oct-16, Volume: 145, Issue:42

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Arthroscopy; Cells, Cultured; Chondrocytes; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Humans; Infliximab; Lupus Erythematosus, Systemic; Methotrexate; Rheumatic Diseases; Scleroderma, Systemic; Stem Cell Transplantation; Tumor Necrosis Factor-alpha

2003
Mucosa-associated lymphoid tissue lymphoma (MALT) of salivary glands and scleroderma: a case report.
    Clinical rheumatology, 2004, Volume: 23, Issue:4

    Topics: Adult; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lymphoma, B-Cell, Marginal Zone; Methotrexate; Parotid Neoplasms; Prednisone; Scleroderma, Systemic

2004
Infliximab treatment in a patient with systemic sclerosis associated with lung fibrosis and pulmonary hypertension.
    Respiration; international review of thoracic diseases, 2008, Volume: 75, Issue:3

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Comorbidity; Drug Therapy, Combination; Female; Fibrosis; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Infliximab; Lung; Methotrexate; Middle Aged; Pulmonary Wedge Pressure; Respiratory Function Tests; Scleroderma, Systemic; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha

2008
Bosentan may induce arthritis flare in patients with scleroderma concomitantly treated with methotrexate.
    Annals of the rheumatic diseases, 2006, Volume: 65, Issue:5

    Topics: Antihypertensive Agents; Arthritis; Bosentan; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Methotrexate; Middle Aged; Scleroderma, Systemic; Sulfonamides

2006
Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:6

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Female; Fibrosis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Methotrexate; Myeloablative Agonists; Scleroderma, Systemic; Skin; Transplantation Conditioning; Transplantation, Homologous

2006
Photochemotherapy and methotrexate used to treat generalized cutaneous scleroderma.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:5

    Topics: Adolescent; Biopsy; Dermatologic Agents; Humans; Male; Methotrexate; PUVA Therapy; Scleroderma, Systemic

2007
Overlap of systemic sclerosis and rheumatoid arthritis.
    The Journal of rheumatology, 2007, Volume: 34, Issue:7

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Female; Hand; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Radiography; Receptors, Tumor Necrosis Factor; Rheumatology; Scleroderma, Systemic; Treatment Outcome

2007
Effects of methotrexate on glycosaminoglycan production by scleroderma fibroblasts in culture.
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:10

    Topics: Adult; Aged; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Fibroblasts; Glycosaminoglycans; Humans; Male; Methotrexate; Middle Aged; Scleroderma, Systemic; Skin

1993
Distinctive features of idiopathic inflammatory myopathies in French Canadians.
    Seminars in arthritis and rheumatism, 1996, Volume: 26, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Rheumatoid; Breast Neoplasms; Canada; Carcinoma; Carcinoma in Situ; Carcinoma, Squamous Cell; Creatine Kinase; Esophageal Neoplasms; Female; Follow-Up Studies; Histidine-tRNA Ligase; Humans; Longitudinal Studies; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Mixed Connective Tissue Disease; Nuclear Envelope; Polymyositis; Prednisone; Pulmonary Fibrosis; Retrospective Studies; Scleroderma, Systemic; Skin Neoplasms; Survival Analysis

1996
Intestinal pseudo-obstruction as an initial presentation of systemic sclerosis in two children.
    British journal of rheumatology, 1997, Volume: 36, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Child, Preschool; Dermatologic Agents; Female; Humans; Intestinal Obstruction; Intestine, Small; Methotrexate; Penicillamine; Prednisone; Radiography; Scleroderma, Systemic; Skin; Stomach

1997
Localized and systemic scleroderma show different histological responses to methotrexate therapy.
    The Journal of pathology, 2001, Volume: 193, Issue:4

    Topics: Adult; Dermatologic Agents; Female; Heparin; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Male; Mast Cells; Methotrexate; Middle Aged; Proteoglycans; Scleroderma, Localized; Scleroderma, Systemic; Tenascin; Treatment Outcome

2001
Penile curvature associated with scleroderma.
    Urology, 2001, Volume: 58, Issue:2

    Topics: Adult; Fibrosis; Humans; Male; Methotrexate; Penile Induration; Scleroderma, Systemic; Ultrasonography

2001
Methotrexate for the treatment of early diffuse scleroderma: comment on the article by Pope et al.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:3

    Topics: Antirheumatic Agents; Child, Preschool; Humans; Methotrexate; Scleroderma, Systemic

2002
Low dose methotrexate treatment in systemic sclerosis.
    The Journal of rheumatology, 1991, Volume: 18, Issue:11

    Topics: Humans; Methotrexate; Pilot Projects; Scleroderma, Systemic

1991
[Tryptophan-induced fasciitis-scleroderma-eosinophilia syndrome].
    Deutsche medizinische Wochenschrift (1946), 1991, Aug-02, Volume: 116, Issue:31-32

    Topics: Aged; Creatine Kinase; Diagnosis, Differential; Eosinophilia; Fasciitis; Female; Fructose-Bisphosphate Aldolase; Glucocorticoids; Humans; Hydroxychloroquine; Methotrexate; Middle Aged; Scleroderma, Systemic; Skin; Syndrome; Time Factors; Tryptophan

1991
Methotrexate treatment in scleroderma.
    The American journal of medicine, 1989, Volume: 87, Issue:1

    Topics: Aged; Female; Humans; Male; Methotrexate; Middle Aged; Scleroderma, Systemic

1989
FDA Arthritis Advisory Committee meeting: methotrexate; guidelines for the clinical evaluation of antiinflammatory drugs; DMSO in scleroderma.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Dimethyl Sulfoxide; Humans; Methotrexate; Scleroderma, Systemic

1986
[Treatment of autoimmune diseases].
    Schweizerische medizinische Wochenschrift, 1971, Oct-02, Volume: 101, Issue:39

    Topics: Adrenal Cortex Hormones; Aged; Anemia, Hemolytic, Autoimmune; Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Blood Protein Disorders; Child, Preschool; Chloramphenicol; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Drug Synergism; Female; Hepatitis; Humans; Immunosuppressive Agents; Long-Term Care; Lupus Vulgaris; Male; Methotrexate; Middle Aged; Nephrosis, Lipoid; Pemphigus; Polyarteritis Nodosa; Postoperative Complications; Purpura, Thrombocytopenic; Scleroderma, Systemic; Transplantation, Homologous

1971
[Scleroderma and Gougerot-Sjögren syndrome. Effect of methotrexate therapy].
    Semaine des hopitaux. Therapeutique, 1973, Volume: 49, Issue:1

    Topics: Adult; Aged; Female; Humans; Methotrexate; Scleroderma, Systemic; Sjogren's Syndrome

1973
[Treatment of "collagen and autoimmune" diseases (author's transl)].
    Wiener klinische Wochenschrift, 1973, Nov-23, Volume: 85, Issue:47

    Topics: Adolescent; Adult; Aminobenzoates; Azathioprine; Chloroquine; Cyclophosphamide; Dermatomyositis; Dextrans; Female; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Norethindrone; Penicillamine; Pregnanes; Scleroderma, Localized; Scleroderma, Systemic

1973
Methotrexate therapy in polymyositis.
    Annals of the rheumatic diseases, 1973, Volume: 32, Issue:6

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biopsy; Creatine Kinase; Dermatomyositis; Female; Fructose-Bisphosphate Aldolase; Humans; L-Lactate Dehydrogenase; Lung; Male; Methotrexate; Middle Aged; Muscular Diseases; Myositis; Pneumonia; Prednisone; Radiography; Scleroderma, Systemic

1973
[Hair changes in immunosuppressive therapy].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1971, Volume: 46, Issue:19

    Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Hair; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Scleroderma, Systemic; Skin Diseases; Vinblastine

1971
[Use of antimetabolites in diseases of auto-aggression].
    Hospital (Rio de Janeiro, Brazil), 1968, Volume: 73, Issue:1

    Topics: Adult; Aged; Autoimmune Diseases; Child, Preschool; Cortisone; Dermatomyositis; Female; Humans; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Middle Aged; Scleroderma, Systemic

1968
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
    Minerva medica, 1970, Jul-11, Volume: 61, Issue:55

    Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Papilloma; Pemphigus; Precancerous Conditions; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms; Virus Diseases

1970
[Treatment of dermatologic lesions using immunosuppressive agents and cytostatics].
    Munchener medizinische Wochenschrift (1950), 1970, Mar-20, Volume: 112, Issue:12

    Topics: Antineoplastic Agents; Azathioprine; Dermatomyositis; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Pemphigus; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms

1970
[Globulin anomalies in skin mucinosis].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:5

    Topics: Adult; Aged; Blood Protein Disorders; Diagnosis, Differential; Female; Humans; Immunoglobulin G; Immunoglobulins; Immunosuppressive Agents; Male; Melphalan; Methotrexate; Middle Aged; Multiple Myeloma; Myxedema; Scleroderma, Systemic; Serum Globulins; Skin Diseases

1970