Page last updated: 2024-08-25

methotrexate and Renal Insufficiency

methotrexate has been researched along with Renal Insufficiency in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.28)	18.7374
1990's	5 (8.20)	18.2507
2000's	18 (29.51)	29.6817
2010's	28 (45.90)	24.3611
2020's	8 (13.11)	2.80

Authors

Authors	Studies
De Pinieux, G; Le Nail, LR; Narciso, B; Salaün, H; Simon, C; Vegas, H; Vinceneux, A	1
Aboelghar, HM; El-Deeb, SM; Elharoun, MS; Elsalam, HBA; Mahmoud, AAS; Zanaty, FM	1
Afkhami Fard, L; Esmaeilzadeh, Z; Ghasemnejad-Berenji, M; Jafari, A; Khezri, MR; Malekinejad, H	1
Iqbal, MA; Mumtaz, T; Tahir, A; Tariq, MA	1
Barnett, JL; Cairns, T; Devaraj, A; Donovan, J; Kokosi, M; Nicholson, AG; Renzoni, EA; Rice, A; Stainer, A; Wells, AU	1
Fisch, A; Gallais Sérézal, I; Johnell, K; Morin, L; Talme, T	1
Assanasen, C; Gramatges, MM; Khalfe, Y; Lucari, B; Mullikin, D; Ranch, D; Schafer, ES; Scheurer, ME; Zobeck, MC	1
Fried, M; Krämer, I; Kühn, M; Rosentreter, J	1
Abhishek, A; Aithal, GP; Card, T; Doherty, M; Grainge, MJ; Mallen, CD; Nakafero, G; Taal, MW; Zhang, W	1
Koratala, A; Ruchi, R	1
Coskun, BN; Dalkilic, E; Ermurat, S; Pehlivan, Y; Tufan, AN; Yağız, B	1
Tian, J; Wang, X; Wang, Z; Yang, Y	1
Jamil, H; Khawla, K; Moez, J; Raida, BS; Saida, G; Sameh, M; Yosra, C; Zouhir, B	1
Dalton, JT; Devine, SM; Edwards, RB; Farag, SS; Grever, MR; Hofmeister, CC; Jansak, BS; Johnston, JS; Lucas, DM; Phelps, MA; Poi, MJ	1
Bartlett, NL; Butler, S; Carson, KR; Liu, W; May, J; Wagner-Johnston, ND	1
Bergsbaken, J; Fermiano, M; Kolesar, JM	1
Brion, A; Chabin, M; Clavert, A; Colombat, P; Cumin, I; Delwail, V; Escoffre-Barbe, M; Gardembas, M; Ingrand, P; Lacotte-Thierry, L; Legouffe, E; Olivier, G; Solal-Celigny, P	1
Shen, DY; Song, H; Xu, XJ; Yang, SL; Zhao, FY	1
Bhattad, S; Gupta, A; Mitra, S; Nada, R; Sharma, A; Singh, S	1
Widemann, BC	1
Cirrincione, CT; Cohen, HJ; Gralow, J; Hurria, A; Jatoi, A; Lichtman, SM; Magrinat, G; Morganstern, DE; Muss, HB; Theodoulou, M; Wolff, AC	1
Dietrich, PY; Espeli, V; Hottinger, AF; Modarressi, A; Ruegg, E	1
Eutsler, E; Ferguson, C; Kitcharoensakkul, M; Orandi, AB; White, AJ	1
Rensma, PL; Rodenburg, RJ; Wijnands, MJ	1
Cheung, KK; Chow, KM; Kwan, BC; Li, PK; Szeto, CC; Tai, MH	1
Lee, SM; Patterson, DM	1
Kellogg, M; Kumar, VS; Law, T	1
Christoulas, D; Dimopoulos, MA; Efstathiou, E; Gavriatopoulou, M; Grapsa, I; Kastritis, E; Matsouka, C; Migkou, M; Mparmparoussi, D; Psimenou, E; Roussou, M; Terpos, E	1
Goto, D; Hayashi, T; Ito, S; Matsumoto, I; Sumida, T	1
Flombaum, C; Meyers, PA	1
Bouafia, F; Franchon, E; Gouraud, A; Pham, BN; Ranchon, F; Rioufol, C; Salles, G; Schwiertz, V; Vantard, N; Vial, T; You, B	1
de Groot, K; Erdbrügger, U	1
Csóka, M; Csordás, K; Eipel, O; Hegyi, M; Kovács, G; Pap, E	1
Fiehn, C	1
Al Omar, S; Tuffaha, HW	1
Çağlar, Y; Gönlüşen, G; Matur, I; Özgür, H; Polat, S; Tuli, A; Yenilmez, ED	1
Binard, A; Devauchelle-Pensec, V; Fautrel, B; Flipo, RM; Jousse-Joulin, S; Le Boëdec, M; Le Loët, X; Marhadour, T; Ménard, JF; Saraux, A	1
MEYERS, MC; PENNER, JA; WEINTRAUB, LR	1
DE VRIES, A; DJALDETTI, M; DULCE, M; PINKHAS, J	1
Aker, M; Bloom, AI; Muszkat, M; Or, R; Resnick, IB; Sasson, T; Shapira, MY; Slavin, S; Verstandig, A; Zilberman, I	1
Kornegay, N; Panetta, JC; Pauley, JL; Pui, CH; Relling, MV; Schmidt, J	1
Kallianpur, AR	1
Caramella, C; de Person, F; Deray, G; Izzedine, H; Karie, S; Launay-Vacher, V	1
Alvegard, TA; Bacci, G; Bernini, G; Bertoni, F; Böhling, T; Brosjö, O; Capanna, R; Comandone, A; Del Prever, AB; Ferrari, S; Longhi, A; Mercuri, M; Müller, C; Picci, P; Ruggieri, P; Saeter, G; Smeland, S; Tienghi, A; Wiebe, T	1
Avery, JK	1
Adamson, PC; Widemann, BC	1
Albiol, S; Bellmunt, J; de Olano, AR; Maroto, P; Pujadas, J	1
Beijnen, JH; Schellens, JH	1
Snyder, RL	1
Herrmann, R; Josting, A; Rimpler, M; Sieniawski, M	1
Auton, T; Borner, K; Fischer, L; Korfel, A; Martus, P; Müller, K; Schwartz, S; Thiel, E	1
Chalumeau, S; Claudel-Bonvoisin, S; Flourié, B; Moussata, D; Nancey, S; Saurin, JC	1
Bateman, J; Penfold, R; Rigby, SP	1
Maiche, AG	1
DuBose, TD; Jaffe, N; Johansen, MJ; Madden, T; Molony, DA; Wall, SM	1
Adams, PT; Jacobson, P; Ratanatharathorn, V; Scalzo, A; Silver, SM; Uberti, JP	1
Bologna, C; Bressolle, F; Combe, B; Kinowski, JM; Sany, J	1
Burge, S; Sheerin, S; Stone, N	1
Blayac, JP; Guinet, C; Hillaire-Buys, D; Mohty, M; Peyriere, H; Rossi, JF	1
Cociglio, M; Hansel, S; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Poiree, M	1
Stadler, WM	1

Reviews

11 review(s) available for methotrexate and Renal Insufficiency

Article	Year
Glucarpidase for the management of elevated methotrexate levels in patients with impaired renal function. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, May-15, Volume: 71, Issue:10 Topics: Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency	2014
[Serious complications during treatment with methotrexate: also in chronic low-dosage use]. Nederlands tijdschrift voor geneeskunde, 2017, Volume: 161 Topics: Aged; Arthritis, Psoriatic; Arthritis, Rheumatoid; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Renal Insufficiency	2017
Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2009, Volume: 15, Issue:4 Topics: Antirheumatic Agents; Arthritis, Psoriatic; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis; Renal Dialysis; Renal Insufficiency	2009
Glucarpidase following high-dose methotrexate: update on development. Expert opinion on biological therapy, 2010, Volume: 10, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Compassionate Use Trials; gamma-Glutamyl Hydrolase; Humans; Kidney Neoplasms; Methotrexate; Renal Insufficiency	2010
[Is methotrexate nephrotoxic? Dose-dependency, comorbidities and comedication]. Zeitschrift fur Rheumatologie, 2011, Volume: 70, Issue:7 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Metabolic Clearance Rate; Methotrexate; Renal Insufficiency; Risk Factors	2011
Glucarpidase for the treatment of life-threatening methotrexate overdose. Drugs of today (Barcelona, Spain : 1998), 2012, Volume: 48, Issue:11 Topics: Animals; Antimetabolites, Antineoplastic; Drug Interactions; Drug Overdose; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency	2012
Baseline laboratory test abnormalities are common in early arthritis but rarely contraindicate methotrexate: study of three cohorts (ESPOIR, VErA, and Brittany). Seminars in arthritis and rheumatism, 2013, Volume: 42, Issue:5 Topics: Alanine Transaminase; Anemia; Antirheumatic Agents; Arthritis; Aspartate Aminotransferases; Cohort Studies; Contraindications; Diagnostic Tests, Routine; Early Diagnosis; Female; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Male; Methotrexate; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Thrombocytopenia	2013
Genomic screening and complications of hematopoietic stem cell transplantation: has the time come? Bone marrow transplantation, 2005, Volume: 35, Issue:1 Topics: Alleles; Genetic Linkage; Genetic Predisposition to Disease; Genome; Genotype; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Iron; Liver; Lung Diseases; Mass Screening; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Models, Chemical; Oligonucleotide Array Sequence Analysis; Oxidants; Polymorphism, Genetic; Renal Insufficiency; Risk Factors; Time Factors; Transplantation Conditioning; Treatment Outcome	2005
Understanding and managing methotrexate nephrotoxicity. The oncologist, 2006, Volume: 11, Issue:6 Topics: Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Methotrexate; Neoplasms; Renal Insufficiency	2006
Gemcitabine in the treatment of advanced transitional cell carcinoma of the urothelium. Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17 Suppl 5 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Comorbidity; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Methotrexate; Pharmacogenetics; Prognosis; Renal Insufficiency; Urinary Bladder Neoplasms; Urothelium; Vinblastine	2006
Gemcitabine doublets in advanced urothelial cancer. Seminars in oncology, 2002, Volume: 29, Issue:1 Suppl 3 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials, Phase II as Topic; Deoxycytidine; Doxorubicin; Forecasting; Gemcitabine; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Prognosis; Renal Insufficiency; Survival Analysis; Trastuzumab; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine	2002

Trials

5 trial(s) available for methotrexate and Renal Insufficiency

Article	Year
Standard pentostatin dose reductions in renal insufficiency are not adequate: selected patients with steroid-refractory acute graft-versus-host disease. Clinical pharmacokinetics, 2013, Volume: 52, Issue:8 Topics: Adenosine Deaminase Inhibitors; Adult; Antibodies, Monoclonal; Area Under Curve; Blood Transfusion, Autologous; Creatinine; Cyclosporine; Drug Resistance; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infliximab; Lymphocyte Transfusion; Male; Methotrexate; Methylprednisolone; Middle Aged; Pentostatin; Renal Insufficiency; Stem Cell Transplantation; Tacrolimus; Young Adult	2013
A phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine, and prednisolone for untreated elderly patients with primary central nervous system lymphoma. The GOELAMS LCP 99 trial. American journal of hematology, 2014, Volume: 89, Issue:11 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Immunocompetence; Infections; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Palliative Care; Prednisolone; Recurrence; Remission Induction; Renal Insufficiency; Thrombocytopenia; Treatment Outcome; Vindesine	2014
Intrahepatic arterial administration of low-dose methotrexate in patients with severe hepatic graft-versus-host disease: an open-label, uncontrolled trial. Clinical therapeutics, 2004, Volume: 26, Issue:3 Topics: Adolescent; Adult; Child; Drug Resistance; Female; Graft vs Host Disease; Hepatic Artery; Humans; Immunosuppressive Agents; Infusions, Intra-Arterial; Male; Methotrexate; Methylprednisolone; Renal Insufficiency	2004
Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Follow-Up Studies; Heart Failure; Humans; Ifosfamide; Italy; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Patient Compliance; Prospective Studies; Renal Insufficiency; Scandinavian and Nordic Countries; Treatment Outcome	2005
Glucarpidase (carboxypeptidase g2) intervention in adult and elderly cancer patients with renal dysfunction and delayed methotrexate elimination after high-dose methotrexate therapy. The oncologist, 2007, Volume: 12, Issue:11 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Kidney Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Renal Insufficiency; Risk Factors; Time Factors; Treatment Outcome	2007

Other Studies

45 other study(ies) available for methotrexate and Renal Insufficiency

Article	Year
Unexpected severe hepatic and skin toxicities during high dose methotrexate course for osteosarcoma. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:6 Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Liver-Specific Organic Anion Transporter 1; Methotrexate; Osteosarcoma; Renal Insufficiency; Stevens-Johnson Syndrome	2022
Evaluation of kidney dysfunction in childhood cancer survivors. Pediatric research, 2022, Volume: 92, Issue:6 Topics: Acute Kidney Injury; Biomarkers; Cancer Survivors; Child; Cisplatin; Creatinine; Cross-Sectional Studies; Cystatin C; Humans; Kidney; Lipocalin-2; Methotrexate; Neoplasms; Renal Insufficiency	2022
Protective effects of sitagliptin on methotrexate-induced nephrotoxicity in rats. Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 2023, Volume: 41, Issue:1-2 Topics: Animals; Antioxidants; Creatinine; Kidney; Methotrexate; Rats; Renal Insufficiency; Sitagliptin Phosphate	2023
Comparative analysis of multiorgan toxicity induced by long term use of disease modifying anti-rheumatic drugs. PloS one, 2023, Volume: 18, Issue:8 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Humans; Leflunomide; Methotrexate; Renal Insufficiency; Urea; Uric Acid	2023
Diffuse alveolar haemorrhage associated with subsequent development of ANCA positivity and emphysema in three young adults. BMC pulmonary medicine, 2019, Oct-24, Volume: 19, Issue:1 Topics: Adolescent; Adult; Antibodies, Antineutrophil Cytoplasmic; Child; Diagnosis, Differential; Female; Glucocorticoids; Hemoptysis; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Immunosuppressive Agents; Lung; Lung Diseases; Male; Methotrexate; Patient Care Management; Peroxidase; Pulmonary Emphysema; Renal Insufficiency; Rituximab; Tomography, X-Ray Computed	2019
Low-dose methotrexate use and safety for older patients with bullous pemphigoid and impaired renal function: A cohort study. Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:6 Topics: Aged; Aged, 80 and over; Cohort Studies; Humans; Methotrexate; Pemphigoid, Bullous; Renal Insufficiency; Retrospective Studies	2020
Hispanic ethnicity is associated with prolonged clearance of high dose methotrexate and severe nephrotoxicity in children and adolescents with acute lymphoblastic leukemia. Leukemia & lymphoma, 2020, Volume: 61, Issue:11 Topics: Adolescent; Child; Ethnicity; Hispanic or Latino; Humans; Infant; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency	2020
Significant interaction between high-dose methotrexate and high-dose piperacillin-tazobactam causing reversible neurotoxicity and renal failure in an osteosarcoma patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Piperacillin; Renal Insufficiency	2021
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline? Rheumatology (Oxford, England), 2021, 12-01, Volume: 60, Issue:12 Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Female; Humans; Immunosuppressive Agents; Incidence; Leflunomide; Liver Diseases; Male; Methotrexate; Middle Aged; Renal Insufficiency; Rheumatic Diseases; Thrombocytopenia; United Kingdom; Withholding Treatment	2021
Glucarpidase for methotrexate nephrotoxicity: another string to our bow. Internal medicine journal, 2017, Volume: 47, Issue:11 Topics: Aged; Antimetabolites, Antineoplastic; Creatinine; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Renal Insufficiency	2017
Methotrexate intoxication: Beyond the adverse events. International journal of rheumatic diseases, 2018, Volume: 21, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Communicable Diseases; Dose-Response Relationship, Drug; Drug Interactions; Female; Fever; Humans; Male; Medication Errors; Methotrexate; Middle Aged; Mucositis; Purpura, Thrombocytopenic; Renal Insufficiency; Retrospective Studies; Risk Assessment; Risk Factors; Turkey	2018
Renal Function and Plasma Methotrexate Concentrations Predict Toxicities in Adults Receiving High-Dose Methotrexate. Medical science monitor : international medical journal of experimental and clinical research, 2018, Oct-29, Volume: 24 Topics: Adult; Asian People; China; Female; Humans; Kidney; Kidney Function Tests; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Retrospective Studies	2018
[Renal amyloidosis complicating adult onset Still's disease: about three cases]. The Pan African medical journal, 2019, Volume: 32 Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Biopsy, Needle; Colchicine; Disease Progression; Female; Humans; Kidney Failure, Chronic; Methotrexate; Middle Aged; Nephrotic Syndrome; Renal Insufficiency; Still's Disease, Adult-Onset	2019
High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis. Leukemia & lymphoma, 2014, Volume: 55, Issue:6 Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Hospital Mortality; Humans; Incidence; Length of Stay; Lymphoma; Male; Methotrexate; Middle Aged; Patient Outcome Assessment; Renal Insufficiency; Retrospective Studies; Risk Factors	2014
Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate. TheScientificWorldJournal, 2015, Volume: 2015 Topics: Adolescent; Biomarkers; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney Function Tests; Male; Methotrexate; Predictive Value of Tests; Renal Insufficiency	2015
Systemic Juvenile Idiopathic Arthritis with Amyloidosis: An Uncommon Complication with a Favourable Outcome. Indian journal of pediatrics, 2016, Volume: 83, Issue:5 Topics: Amyloidosis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Child; Humans; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Methotrexate; Microscopy, Polarization; Renal Insufficiency; Treatment Outcome	2016
Reply to: Glucarpidase for the Treatment of Methotrexate-Induced Renal Dysfunction and Delayed Methotrexate Excretion. Pediatric blood & cancer, 2016, Volume: 63, Issue:2 Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Renal Insufficiency	2016
Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-01, Volume: 34, Issue:7 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Capecitabine; Creatinine; Cyclophosphamide; Female; Fluorouracil; Humans; Kidney Function Tests; Methotrexate; Prognosis; Renal Insufficiency; Survival Rate; Tamoxifen; Treatment Outcome	2016
Weekly Multi-agent Chemotherapy (CMF-b) for Advanced Non-melanoma Skin Cancer. Anticancer research, 2016, Volume: 36, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Carboplatin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Renal Insufficiency; Retrospective Studies; Salvage Therapy; Skin Neoplasms	2016
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent. Pediatric rheumatology online journal, 2016, Nov-10, Volume: 14, Issue:1 Topics: Adalimumab; Adolescent; Antirheumatic Agents; Diagnosis, Differential; Female; Granuloma; Humans; Hypercalcemia; Methotrexate; Muscle Weakness; Myositis; Prednisone; Renal Insufficiency; Sarcoidosis; Treatment Outcome	2016
Liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for monitoring methotrexate in the setting of carboxypeptidase-G2 therapy. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603 Topics: Chromatography, High Pressure Liquid; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2010
Lenalidomide and dexamethasone for the treatment of refractory/relapsed multiple myeloma: dosing of lenalidomide according to renal function and effect on renal impairment. European journal of haematology, 2010, Volume: 85, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Creatinine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Kidney; Lenalidomide; Male; Methotrexate; Middle Aged; Multiple Myeloma; Renal Insufficiency; Thalidomide	2010
Elevated level of serum cystatin-C concentration is a useful predictor for myelosuppression induced by methotrexate for treatment of rheumatoid arthritis. Modern rheumatology, 2010, Volume: 20, Issue:6 Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow; Bone Marrow Diseases; Creatinine; Cystatin C; Female; Humans; Immunosuppressive Agents; Kidney Function Tests; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Renal Insufficiency	2010
High-dose methotrexate-induced renal dysfunction: is glucarpidase necessary for rescue? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-01, Volume: 29, Issue:7 Topics: Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; gamma-Glutamyl Hydrolase; Humans; Kidney Function Tests; Male; Methotrexate; Primary Prevention; Renal Insufficiency; Risk Assessment; Time Factors; Treatment Outcome	2011
Suspicion of drug-drug interaction between high-dose methotrexate and proton pump inhibitors: a case report - should the practice be changed? Chemotherapy, 2011, Volume: 57, Issue:3 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acyclovir; Antimetabolites, Antineoplastic; Antiviral Agents; Drug Interactions; Female; Fluoxetine; Humans; Methotrexate; Middle Aged; Pantoprazole; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proton Pump Inhibitors; Renal Insufficiency; Valacyclovir; Valine	2011
[Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies]. Orvosi hetilap, 2011, Oct-02, Volume: 152, Issue:40 Topics: Adolescent; Antimetabolites, Antineoplastic; Blood Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Drug Administration Schedule; Female; Humans; Kidney; Liver; Liver Failure; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stomatitis; Time Factors; Treatment Outcome	2011
[The other opinion: nephrotoxicity of low-dose methotrexate - a problem which does not exist]. Zeitschrift fur Rheumatologie, 2011, Volume: 70, Issue:10 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrexate; Renal Insufficiency	2011
Ultrastructural evaluation of the effect of N-acetylcysteine on methotrexate nephrotoxicity in rats. Histology and histopathology, 2013, Volume: 28, Issue:7 Topics: Acetylcysteine; Animals; Blood Urea Nitrogen; Creatinine; Glutathione Peroxidase; Immunohistochemistry; Ki-67 Antigen; Kidney; Kidney Glomerulus; Male; Malondialdehyde; Methotrexate; Rats; Rats, Wistar; Renal Insufficiency; Superoxide Dismutase	2013
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS. Archives of internal medicine, 1964, Volume: 113 Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; Metabolism; Methotrexate; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency; Toxicology; Uric Acid; Urine	1964
[COMPLICATIONS OF LEUKEMIA AND THEIR TREATMENT]. Harefuah, 1963, Dec-01, Volume: 65 Topics: Acute Kidney Injury; Beverages; Erythromycin; Humans; Leukemia; Leukemia, Myeloid; Lung Abscess; Lung Diseases, Fungal; Methotrexate; Nystatin; Papilledema; Renal Insufficiency	1963
Late-onset delayed excretion of methotrexate. Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:2 Topics: Adolescent; Antimetabolites, Antineoplastic; Ascites; Humans; Male; Methotrexate; Pleural Effusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency	2004
Is low-dose methotrexate nephrotoxic? Case report and review of the literature. Clinical nephrology, 2005, Volume: 64, Issue:4 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Female; Follow-Up Studies; Humans; Kidney Glomerulus; Methotrexate; Middle Aged; Renal Insufficiency	2005
Be careful about what you sign. Tennessee medicine : journal of the Tennessee Medical Association, 2005, Volume: 98, Issue:12 Topics: Aged, 80 and over; Fatal Outcome; Female; Humans; Liability, Legal; Medication Errors; Methotrexate; Quality of Health Care; Renal Insufficiency	2005
[Management recommendations in patients with methotrexate intoxication]. Nederlands tijdschrift voor geneeskunde, 2007, Feb-10, Volume: 151, Issue:6 Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Humans; Kidney; Leucovorin; Lymphoma; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Renal Insufficiency; Thymidine; Vitamin B Complex	2007
Resumption of high-dose methotrexate after methotrexate-induced nephrotoxicity and carboxypeptidase G2 use. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Jun-01, Volume: 64, Issue:11 Topics: Adolescent; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasm Recurrence, Local; Renal Insufficiency; Retreatment	2007
Successful carboxypeptidase G2 rescue of a high-risk elderly Hodgkin lymphoma patient with methotrexate intoxication and renal failure. Leukemia & lymphoma, 2007, Volume: 48, Issue:8 Topics: gamma-Glutamyl Hydrolase; Hodgkin Disease; Humans; Male; Methotrexate; Middle Aged; Renal Insufficiency	2007
[Pancytopenia induced by two low-dose injections of methotrexate in a patient treated for ulcerative colitis]. Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:12 Topics: Aged; Colitis, Ulcerative; Folic Acid Antagonists; Humans; Hypoalbuminemia; Immunosuppressive Agents; Injections, Subcutaneous; Klebsiella Infections; Klebsiella pneumoniae; Male; Methotrexate; Pancytopenia; Proctocolitis; Renal Insufficiency; Risk Factors; Sepsis	2007
Comment on: Kidney disease in RA patients: prevalence and implication on RA-related drugs management: the MATRIX study. Rheumatology (Oxford, England), 2008, Volume: 47, Issue:8 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Fatal Outcome; Female; Humans; Methotrexate; Renal Insufficiency	2008
Acute renal insufficiency due to viral infection caused by cytomegalovirus (CMV) during treatment with methotrexate. Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:7 Topics: Aged; Antimetabolites, Antineoplastic; Cytomegalovirus Infections; Humans; Immunosuppressive Agents; Lymphoma, B-Cell; Male; Methotrexate; Renal Insufficiency	1995
Effective clearance of methotrexate using high-flux hemodialysis membranes. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:6 Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; Humans; Male; Membranes, Artificial; Methotrexate; Middle Aged; Neoplasms; Renal Dialysis; Renal Insufficiency	1996
Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies. Bone marrow transplantation, 1997, Volume: 19, Issue:12 Topics: Acute Disease; Adult; Bone Marrow Transplantation; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Humans; Hyperbilirubinemia; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prognosis; Recurrence; Renal Insufficiency; Tacrolimus; Transplantation, Homologous	1997
Effects of moderate renal insufficiency on pharmacokinetics of methotrexate in rheumatoid arthritis patients. Annals of the rheumatic diseases, 1998, Volume: 57, Issue:2 Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Female; Humans; Male; Methotrexate; Middle Aged; Renal Insufficiency	1998
Toxic epidermal necrolysis and graft vs. host disease: a clinical spectrum but a diagnostic dilemma. Clinical and experimental dermatology, 1999, Volume: 24, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Diagnosis, Differential; Diarrhea; Fatal Outcome; Fever; Graft vs Host Disease; Humans; Liver Failure; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Platelet Transfusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stevens-Johnson Syndrome	1999
Carboxypeptidase G2 rescue in delayed methotrexate elimination in renal failure. Leukemia & lymphoma, 2000, Volume: 37, Issue:3-4 Topics: Aged; Brain Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Infusions, Intravenous; Lymphoma; Methotrexate; Renal Insufficiency	2000
Reversal of neurologic disturbances related to high-dose methotrexate by aminophylline. Medical and pediatric oncology, 2001, Volume: 36, Issue:6 Topics: Aminophylline; Antimetabolites, Antineoplastic; Child; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency	2001