methotrexate has been researched along with Renal Insufficiency in 61 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (3.28) | 18.7374 |
1990's | 5 (8.20) | 18.2507 |
2000's | 18 (29.51) | 29.6817 |
2010's | 28 (45.90) | 24.3611 |
2020's | 8 (13.11) | 2.80 |
Authors | Studies |
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De Pinieux, G; Le Nail, LR; Narciso, B; Salaün, H; Simon, C; Vegas, H; Vinceneux, A | 1 |
Aboelghar, HM; El-Deeb, SM; Elharoun, MS; Elsalam, HBA; Mahmoud, AAS; Zanaty, FM | 1 |
Afkhami Fard, L; Esmaeilzadeh, Z; Ghasemnejad-Berenji, M; Jafari, A; Khezri, MR; Malekinejad, H | 1 |
Iqbal, MA; Mumtaz, T; Tahir, A; Tariq, MA | 1 |
Barnett, JL; Cairns, T; Devaraj, A; Donovan, J; Kokosi, M; Nicholson, AG; Renzoni, EA; Rice, A; Stainer, A; Wells, AU | 1 |
Fisch, A; Gallais Sérézal, I; Johnell, K; Morin, L; Talme, T | 1 |
Assanasen, C; Gramatges, MM; Khalfe, Y; Lucari, B; Mullikin, D; Ranch, D; Schafer, ES; Scheurer, ME; Zobeck, MC | 1 |
Fried, M; Krämer, I; Kühn, M; Rosentreter, J | 1 |
Abhishek, A; Aithal, GP; Card, T; Doherty, M; Grainge, MJ; Mallen, CD; Nakafero, G; Taal, MW; Zhang, W | 1 |
Koratala, A; Ruchi, R | 1 |
Coskun, BN; Dalkilic, E; Ermurat, S; Pehlivan, Y; Tufan, AN; Yağız, B | 1 |
Tian, J; Wang, X; Wang, Z; Yang, Y | 1 |
Jamil, H; Khawla, K; Moez, J; Raida, BS; Saida, G; Sameh, M; Yosra, C; Zouhir, B | 1 |
Dalton, JT; Devine, SM; Edwards, RB; Farag, SS; Grever, MR; Hofmeister, CC; Jansak, BS; Johnston, JS; Lucas, DM; Phelps, MA; Poi, MJ | 1 |
Bartlett, NL; Butler, S; Carson, KR; Liu, W; May, J; Wagner-Johnston, ND | 1 |
Bergsbaken, J; Fermiano, M; Kolesar, JM | 1 |
Brion, A; Chabin, M; Clavert, A; Colombat, P; Cumin, I; Delwail, V; Escoffre-Barbe, M; Gardembas, M; Ingrand, P; Lacotte-Thierry, L; Legouffe, E; Olivier, G; Solal-Celigny, P | 1 |
Shen, DY; Song, H; Xu, XJ; Yang, SL; Zhao, FY | 1 |
Bhattad, S; Gupta, A; Mitra, S; Nada, R; Sharma, A; Singh, S | 1 |
Widemann, BC | 1 |
Cirrincione, CT; Cohen, HJ; Gralow, J; Hurria, A; Jatoi, A; Lichtman, SM; Magrinat, G; Morganstern, DE; Muss, HB; Theodoulou, M; Wolff, AC | 1 |
Dietrich, PY; Espeli, V; Hottinger, AF; Modarressi, A; Ruegg, E | 1 |
Eutsler, E; Ferguson, C; Kitcharoensakkul, M; Orandi, AB; White, AJ | 1 |
Rensma, PL; Rodenburg, RJ; Wijnands, MJ | 1 |
Cheung, KK; Chow, KM; Kwan, BC; Li, PK; Szeto, CC; Tai, MH | 1 |
Lee, SM; Patterson, DM | 1 |
Kellogg, M; Kumar, VS; Law, T | 1 |
Christoulas, D; Dimopoulos, MA; Efstathiou, E; Gavriatopoulou, M; Grapsa, I; Kastritis, E; Matsouka, C; Migkou, M; Mparmparoussi, D; Psimenou, E; Roussou, M; Terpos, E | 1 |
Goto, D; Hayashi, T; Ito, S; Matsumoto, I; Sumida, T | 1 |
Flombaum, C; Meyers, PA | 1 |
Bouafia, F; Franchon, E; Gouraud, A; Pham, BN; Ranchon, F; Rioufol, C; Salles, G; Schwiertz, V; Vantard, N; Vial, T; You, B | 1 |
de Groot, K; Erdbrügger, U | 1 |
Csóka, M; Csordás, K; Eipel, O; Hegyi, M; Kovács, G; Pap, E | 1 |
Fiehn, C | 1 |
Al Omar, S; Tuffaha, HW | 1 |
Çağlar, Y; Gönlüşen, G; Matur, I; Özgür, H; Polat, S; Tuli, A; Yenilmez, ED | 1 |
Binard, A; Devauchelle-Pensec, V; Fautrel, B; Flipo, RM; Jousse-Joulin, S; Le Boëdec, M; Le Loët, X; Marhadour, T; Ménard, JF; Saraux, A | 1 |
MEYERS, MC; PENNER, JA; WEINTRAUB, LR | 1 |
DE VRIES, A; DJALDETTI, M; DULCE, M; PINKHAS, J | 1 |
Aker, M; Bloom, AI; Muszkat, M; Or, R; Resnick, IB; Sasson, T; Shapira, MY; Slavin, S; Verstandig, A; Zilberman, I | 1 |
Kornegay, N; Panetta, JC; Pauley, JL; Pui, CH; Relling, MV; Schmidt, J | 1 |
Kallianpur, AR | 1 |
Caramella, C; de Person, F; Deray, G; Izzedine, H; Karie, S; Launay-Vacher, V | 1 |
Alvegard, TA; Bacci, G; Bernini, G; Bertoni, F; Böhling, T; Brosjö, O; Capanna, R; Comandone, A; Del Prever, AB; Ferrari, S; Longhi, A; Mercuri, M; Müller, C; Picci, P; Ruggieri, P; Saeter, G; Smeland, S; Tienghi, A; Wiebe, T | 1 |
Avery, JK | 1 |
Adamson, PC; Widemann, BC | 1 |
Albiol, S; Bellmunt, J; de Olano, AR; Maroto, P; Pujadas, J | 1 |
Beijnen, JH; Schellens, JH | 1 |
Snyder, RL | 1 |
Herrmann, R; Josting, A; Rimpler, M; Sieniawski, M | 1 |
Auton, T; Borner, K; Fischer, L; Korfel, A; Martus, P; Müller, K; Schwartz, S; Thiel, E | 1 |
Chalumeau, S; Claudel-Bonvoisin, S; Flourié, B; Moussata, D; Nancey, S; Saurin, JC | 1 |
Bateman, J; Penfold, R; Rigby, SP | 1 |
Maiche, AG | 1 |
DuBose, TD; Jaffe, N; Johansen, MJ; Madden, T; Molony, DA; Wall, SM | 1 |
Adams, PT; Jacobson, P; Ratanatharathorn, V; Scalzo, A; Silver, SM; Uberti, JP | 1 |
Bologna, C; Bressolle, F; Combe, B; Kinowski, JM; Sany, J | 1 |
Burge, S; Sheerin, S; Stone, N | 1 |
Blayac, JP; Guinet, C; Hillaire-Buys, D; Mohty, M; Peyriere, H; Rossi, JF | 1 |
Cociglio, M; Hansel, S; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Poiree, M | 1 |
Stadler, WM | 1 |
11 review(s) available for methotrexate and Renal Insufficiency
Article | Year |
---|---|
Glucarpidase for the management of elevated methotrexate levels in patients with impaired renal function.
Topics: Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency | 2014 |
[Serious complications during treatment with methotrexate: also in chronic low-dosage use].
Topics: Aged; Arthritis, Psoriatic; Arthritis, Rheumatoid; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Renal Insufficiency | 2017 |
Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis; Renal Dialysis; Renal Insufficiency | 2009 |
Glucarpidase following high-dose methotrexate: update on development.
Topics: Animals; Antimetabolites, Antineoplastic; Compassionate Use Trials; gamma-Glutamyl Hydrolase; Humans; Kidney Neoplasms; Methotrexate; Renal Insufficiency | 2010 |
[Is methotrexate nephrotoxic? Dose-dependency, comorbidities and comedication].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Metabolic Clearance Rate; Methotrexate; Renal Insufficiency; Risk Factors | 2011 |
Glucarpidase for the treatment of life-threatening methotrexate overdose.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Interactions; Drug Overdose; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency | 2012 |
Baseline laboratory test abnormalities are common in early arthritis but rarely contraindicate methotrexate: study of three cohorts (ESPOIR, VErA, and Brittany).
Topics: Alanine Transaminase; Anemia; Antirheumatic Agents; Arthritis; Aspartate Aminotransferases; Cohort Studies; Contraindications; Diagnostic Tests, Routine; Early Diagnosis; Female; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Male; Methotrexate; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Thrombocytopenia | 2013 |
Genomic screening and complications of hematopoietic stem cell transplantation: has the time come?
Topics: Alleles; Genetic Linkage; Genetic Predisposition to Disease; Genome; Genotype; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Iron; Liver; Lung Diseases; Mass Screening; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Models, Chemical; Oligonucleotide Array Sequence Analysis; Oxidants; Polymorphism, Genetic; Renal Insufficiency; Risk Factors; Time Factors; Transplantation Conditioning; Treatment Outcome | 2005 |
Understanding and managing methotrexate nephrotoxicity.
Topics: Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Methotrexate; Neoplasms; Renal Insufficiency | 2006 |
Gemcitabine in the treatment of advanced transitional cell carcinoma of the urothelium.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Comorbidity; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Methotrexate; Pharmacogenetics; Prognosis; Renal Insufficiency; Urinary Bladder Neoplasms; Urothelium; Vinblastine | 2006 |
Gemcitabine doublets in advanced urothelial cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials, Phase II as Topic; Deoxycytidine; Doxorubicin; Forecasting; Gemcitabine; Humans; Methotrexate; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Prognosis; Renal Insufficiency; Survival Analysis; Trastuzumab; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2002 |
5 trial(s) available for methotrexate and Renal Insufficiency
Article | Year |
---|---|
Standard pentostatin dose reductions in renal insufficiency are not adequate: selected patients with steroid-refractory acute graft-versus-host disease.
Topics: Adenosine Deaminase Inhibitors; Adult; Antibodies, Monoclonal; Area Under Curve; Blood Transfusion, Autologous; Creatinine; Cyclosporine; Drug Resistance; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infliximab; Lymphocyte Transfusion; Male; Methotrexate; Methylprednisolone; Middle Aged; Pentostatin; Renal Insufficiency; Stem Cell Transplantation; Tacrolimus; Young Adult | 2013 |
A phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine, and prednisolone for untreated elderly patients with primary central nervous system lymphoma. The GOELAMS LCP 99 trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Immunocompetence; Infections; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Palliative Care; Prednisolone; Recurrence; Remission Induction; Renal Insufficiency; Thrombocytopenia; Treatment Outcome; Vindesine | 2014 |
Intrahepatic arterial administration of low-dose methotrexate in patients with severe hepatic graft-versus-host disease: an open-label, uncontrolled trial.
Topics: Adolescent; Adult; Child; Drug Resistance; Female; Graft vs Host Disease; Hepatic Artery; Humans; Immunosuppressive Agents; Infusions, Intra-Arterial; Male; Methotrexate; Methylprednisolone; Renal Insufficiency | 2004 |
Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Female; Follow-Up Studies; Heart Failure; Humans; Ifosfamide; Italy; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Patient Compliance; Prospective Studies; Renal Insufficiency; Scandinavian and Nordic Countries; Treatment Outcome | 2005 |
Glucarpidase (carboxypeptidase g2) intervention in adult and elderly cancer patients with renal dysfunction and delayed methotrexate elimination after high-dose methotrexate therapy.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Kidney Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Renal Insufficiency; Risk Factors; Time Factors; Treatment Outcome | 2007 |
45 other study(ies) available for methotrexate and Renal Insufficiency
Article | Year |
---|---|
Unexpected severe hepatic and skin toxicities during high dose methotrexate course for osteosarcoma.
Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Liver-Specific Organic Anion Transporter 1; Methotrexate; Osteosarcoma; Renal Insufficiency; Stevens-Johnson Syndrome | 2022 |
Evaluation of kidney dysfunction in childhood cancer survivors.
Topics: Acute Kidney Injury; Biomarkers; Cancer Survivors; Child; Cisplatin; Creatinine; Cross-Sectional Studies; Cystatin C; Humans; Kidney; Lipocalin-2; Methotrexate; Neoplasms; Renal Insufficiency | 2022 |
Protective effects of sitagliptin on methotrexate-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Creatinine; Kidney; Methotrexate; Rats; Renal Insufficiency; Sitagliptin Phosphate | 2023 |
Comparative analysis of multiorgan toxicity induced by long term use of disease modifying anti-rheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Humans; Leflunomide; Methotrexate; Renal Insufficiency; Urea; Uric Acid | 2023 |
Diffuse alveolar haemorrhage associated with subsequent development of ANCA positivity and emphysema in three young adults.
Topics: Adolescent; Adult; Antibodies, Antineutrophil Cytoplasmic; Child; Diagnosis, Differential; Female; Glucocorticoids; Hemoptysis; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Immunosuppressive Agents; Lung; Lung Diseases; Male; Methotrexate; Patient Care Management; Peroxidase; Pulmonary Emphysema; Renal Insufficiency; Rituximab; Tomography, X-Ray Computed | 2019 |
Low-dose methotrexate use and safety for older patients with bullous pemphigoid and impaired renal function: A cohort study.
Topics: Aged; Aged, 80 and over; Cohort Studies; Humans; Methotrexate; Pemphigoid, Bullous; Renal Insufficiency; Retrospective Studies | 2020 |
Hispanic ethnicity is associated with prolonged clearance of high dose methotrexate and severe nephrotoxicity in children and adolescents with acute lymphoblastic leukemia.
Topics: Adolescent; Child; Ethnicity; Hispanic or Latino; Humans; Infant; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency | 2020 |
Significant interaction between high-dose methotrexate and high-dose piperacillin-tazobactam causing reversible neurotoxicity and renal failure in an osteosarcoma patient.
Topics: Adolescent; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Osteosarcoma; Piperacillin; Renal Insufficiency | 2021 |
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Female; Humans; Immunosuppressive Agents; Incidence; Leflunomide; Liver Diseases; Male; Methotrexate; Middle Aged; Renal Insufficiency; Rheumatic Diseases; Thrombocytopenia; United Kingdom; Withholding Treatment | 2021 |
Glucarpidase for methotrexate nephrotoxicity: another string to our bow.
Topics: Aged; Antimetabolites, Antineoplastic; Creatinine; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Renal Insufficiency | 2017 |
Methotrexate intoxication: Beyond the adverse events.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Communicable Diseases; Dose-Response Relationship, Drug; Drug Interactions; Female; Fever; Humans; Male; Medication Errors; Methotrexate; Middle Aged; Mucositis; Purpura, Thrombocytopenic; Renal Insufficiency; Retrospective Studies; Risk Assessment; Risk Factors; Turkey | 2018 |
Renal Function and Plasma Methotrexate Concentrations Predict Toxicities in Adults Receiving High-Dose Methotrexate.
Topics: Adult; Asian People; China; Female; Humans; Kidney; Kidney Function Tests; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Retrospective Studies | 2018 |
[Renal amyloidosis complicating adult onset Still's disease: about three cases].
Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Biopsy, Needle; Colchicine; Disease Progression; Female; Humans; Kidney Failure, Chronic; Methotrexate; Middle Aged; Nephrotic Syndrome; Renal Insufficiency; Still's Disease, Adult-Onset | 2019 |
High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Female; Hospital Mortality; Humans; Incidence; Length of Stay; Lymphoma; Male; Methotrexate; Middle Aged; Patient Outcome Assessment; Renal Insufficiency; Retrospective Studies; Risk Factors | 2014 |
Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Kidney Function Tests; Male; Methotrexate; Predictive Value of Tests; Renal Insufficiency | 2015 |
Systemic Juvenile Idiopathic Arthritis with Amyloidosis: An Uncommon Complication with a Favourable Outcome.
Topics: Amyloidosis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Juvenile; Biopsy; Child; Humans; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Methotrexate; Microscopy, Polarization; Renal Insufficiency; Treatment Outcome | 2016 |
Reply to: Glucarpidase for the Treatment of Methotrexate-Induced Renal Dysfunction and Delayed Methotrexate Excretion.
Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Male; Methotrexate; Renal Insufficiency | 2016 |
Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Capecitabine; Creatinine; Cyclophosphamide; Female; Fluorouracil; Humans; Kidney Function Tests; Methotrexate; Prognosis; Renal Insufficiency; Survival Rate; Tamoxifen; Treatment Outcome | 2016 |
Weekly Multi-agent Chemotherapy (CMF-b) for Advanced Non-melanoma Skin Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Carboplatin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Remission Induction; Renal Insufficiency; Retrospective Studies; Salvage Therapy; Skin Neoplasms | 2016 |
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent.
Topics: Adalimumab; Adolescent; Antirheumatic Agents; Diagnosis, Differential; Female; Granuloma; Humans; Hypercalcemia; Methotrexate; Muscle Weakness; Myositis; Prednisone; Renal Insufficiency; Sarcoidosis; Treatment Outcome | 2016 |
Liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for monitoring methotrexate in the setting of carboxypeptidase-G2 therapy.
Topics: Chromatography, High Pressure Liquid; gamma-Glutamyl Hydrolase; Humans; Methotrexate; Renal Insufficiency; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Lenalidomide and dexamethasone for the treatment of refractory/relapsed multiple myeloma: dosing of lenalidomide according to renal function and effect on renal impairment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Creatinine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Kidney; Lenalidomide; Male; Methotrexate; Middle Aged; Multiple Myeloma; Renal Insufficiency; Thalidomide | 2010 |
Elevated level of serum cystatin-C concentration is a useful predictor for myelosuppression induced by methotrexate for treatment of rheumatoid arthritis.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow; Bone Marrow Diseases; Creatinine; Cystatin C; Female; Humans; Immunosuppressive Agents; Kidney Function Tests; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Renal Insufficiency | 2010 |
High-dose methotrexate-induced renal dysfunction: is glucarpidase necessary for rescue?
Topics: Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; gamma-Glutamyl Hydrolase; Humans; Kidney Function Tests; Male; Methotrexate; Primary Prevention; Renal Insufficiency; Risk Assessment; Time Factors; Treatment Outcome | 2011 |
Suspicion of drug-drug interaction between high-dose methotrexate and proton pump inhibitors: a case report - should the practice be changed?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acyclovir; Antimetabolites, Antineoplastic; Antiviral Agents; Drug Interactions; Female; Fluoxetine; Humans; Methotrexate; Middle Aged; Pantoprazole; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proton Pump Inhibitors; Renal Insufficiency; Valacyclovir; Valine | 2011 |
[Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies].
Topics: Adolescent; Antimetabolites, Antineoplastic; Blood Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Drug Administration Schedule; Female; Humans; Kidney; Liver; Liver Failure; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stomatitis; Time Factors; Treatment Outcome | 2011 |
[The other opinion: nephrotoxicity of low-dose methotrexate - a problem which does not exist].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrexate; Renal Insufficiency | 2011 |
Ultrastructural evaluation of the effect of N-acetylcysteine on methotrexate nephrotoxicity in rats.
Topics: Acetylcysteine; Animals; Blood Urea Nitrogen; Creatinine; Glutathione Peroxidase; Immunohistochemistry; Ki-67 Antigen; Kidney; Kidney Glomerulus; Male; Malondialdehyde; Methotrexate; Rats; Rats, Wistar; Renal Insufficiency; Superoxide Dismutase | 2013 |
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS.
Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; Metabolism; Methotrexate; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency; Toxicology; Uric Acid; Urine | 1964 |
[COMPLICATIONS OF LEUKEMIA AND THEIR TREATMENT].
Topics: Acute Kidney Injury; Beverages; Erythromycin; Humans; Leukemia; Leukemia, Myeloid; Lung Abscess; Lung Diseases, Fungal; Methotrexate; Nystatin; Papilledema; Renal Insufficiency | 1963 |
Late-onset delayed excretion of methotrexate.
Topics: Adolescent; Antimetabolites, Antineoplastic; Ascites; Humans; Male; Methotrexate; Pleural Effusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency | 2004 |
Is low-dose methotrexate nephrotoxic? Case report and review of the literature.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Female; Follow-Up Studies; Humans; Kidney Glomerulus; Methotrexate; Middle Aged; Renal Insufficiency | 2005 |
Be careful about what you sign.
Topics: Aged, 80 and over; Fatal Outcome; Female; Humans; Liability, Legal; Medication Errors; Methotrexate; Quality of Health Care; Renal Insufficiency | 2005 |
[Management recommendations in patients with methotrexate intoxication].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Humans; Kidney; Leucovorin; Lymphoma; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Renal Insufficiency; Thymidine; Vitamin B Complex | 2007 |
Resumption of high-dose methotrexate after methotrexate-induced nephrotoxicity and carboxypeptidase G2 use.
Topics: Adolescent; Antimetabolites, Antineoplastic; gamma-Glutamyl Hydrolase; Humans; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Neoplasm Recurrence, Local; Renal Insufficiency; Retreatment | 2007 |
Successful carboxypeptidase G2 rescue of a high-risk elderly Hodgkin lymphoma patient with methotrexate intoxication and renal failure.
Topics: gamma-Glutamyl Hydrolase; Hodgkin Disease; Humans; Male; Methotrexate; Middle Aged; Renal Insufficiency | 2007 |
[Pancytopenia induced by two low-dose injections of methotrexate in a patient treated for ulcerative colitis].
Topics: Aged; Colitis, Ulcerative; Folic Acid Antagonists; Humans; Hypoalbuminemia; Immunosuppressive Agents; Injections, Subcutaneous; Klebsiella Infections; Klebsiella pneumoniae; Male; Methotrexate; Pancytopenia; Proctocolitis; Renal Insufficiency; Risk Factors; Sepsis | 2007 |
Comment on: Kidney disease in RA patients: prevalence and implication on RA-related drugs management: the MATRIX study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Fatal Outcome; Female; Humans; Methotrexate; Renal Insufficiency | 2008 |
Acute renal insufficiency due to viral infection caused by cytomegalovirus (CMV) during treatment with methotrexate.
Topics: Aged; Antimetabolites, Antineoplastic; Cytomegalovirus Infections; Humans; Immunosuppressive Agents; Lymphoma, B-Cell; Male; Methotrexate; Renal Insufficiency | 1995 |
Effective clearance of methotrexate using high-flux hemodialysis membranes.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; Humans; Male; Membranes, Artificial; Methotrexate; Middle Aged; Neoplasms; Renal Dialysis; Renal Insufficiency | 1996 |
Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies.
Topics: Acute Disease; Adult; Bone Marrow Transplantation; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Humans; Hyperbilirubinemia; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prognosis; Recurrence; Renal Insufficiency; Tacrolimus; Transplantation, Homologous | 1997 |
Effects of moderate renal insufficiency on pharmacokinetics of methotrexate in rheumatoid arthritis patients.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Female; Humans; Male; Methotrexate; Middle Aged; Renal Insufficiency | 1998 |
Toxic epidermal necrolysis and graft vs. host disease: a clinical spectrum but a diagnostic dilemma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Diagnosis, Differential; Diarrhea; Fatal Outcome; Fever; Graft vs Host Disease; Humans; Liver Failure; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Platelet Transfusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stevens-Johnson Syndrome | 1999 |
Carboxypeptidase G2 rescue in delayed methotrexate elimination in renal failure.
Topics: Aged; Brain Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Infusions, Intravenous; Lymphoma; Methotrexate; Renal Insufficiency | 2000 |
Reversal of neurologic disturbances related to high-dose methotrexate by aminophylline.
Topics: Aminophylline; Antimetabolites, Antineoplastic; Child; Humans; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency | 2001 |