methotrexate has been researched along with Polyploid in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dabrowska, M; Mosieniak, G; Rode, W; Sikora, E; Skierski, J | 1 |
| Fox, BW; McGown, AT; Poppitt, DG; Swindell, R | 1 |
| Haug, BA; Krygier-Stojalowska, A; Pilichowska, ME; Schröter, P | 1 |
| Kavallaris, M; Pittman, SM; Stewart, BW | 1 |
| Chang, CC; Hashimoto, MW; Kobayashi, N; Mori, T; Nikaido, O; Trosko, JE | 1 |
| Blom, J; Kaplan, SS; Rybka, WB; Shekhter-Levin, S | 1 |
| Finley, WH | 1 |
| Siminovitch, L | 1 |
| Choi, GH; Hole, H; Spahlinger, B | 1 |
| Hamlin, JL; Trask, BJ | 1 |
| Altaner, C; Hladká, M | 1 |
| Hauschka, TS; Holdridge, BA | 1 |
| Arroyo Nombela, JJ; Rodriguez Murcia, C | 1 |
1 review(s) available for methotrexate and Polyploid
| Article | Year |
|---|---|
On the nature of hereditable variation in cultured somatic cells.
Topics: Amanitins; Azaguanine; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromosomes; Colchicine; Cycloheximide; Diploidy; Drug Resistance; Genes; Genes, Lethal; Genes, Recessive; Genetic Variation; Hybrid Cells; Hydroxyurea; Immunoglobulins; Lectins; Methotrexate; Mutation; Ouabain; Phenotype; Polyploidy; Temperature | 1976 |
1 trial(s) available for methotrexate and Polyploid
| Article | Year |
|---|---|
Malignant gliomas--ploidy and DNA-content before and after therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Diploidy; DNA, Neoplasm; Female; Glioma; Humans; Male; Methotrexate; Middle Aged; Ploidies; Polyploidy; Prednisone; Radiotherapy Dosage; Vincristine | 1994 |
11 other study(ies) available for methotrexate and Polyploid
| Article | Year |
|---|---|
Methotrexate-induced senescence in human adenocarcinoma cells is accompanied by induction of p21(waf1/cip1) expression and lack of polyploidy.
Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Humans; Methotrexate; Polyploidy | 2009 |
The effect of vinca alkaloids in enhancing the sensitivity of a methotrexate-resistant (L1210/R7A) line, studied by flow cytometric and chromosome number analysis.
Topics: Animals; Cell Division; Cell Line; Chromosomes; DNA, Neoplasm; Drug Resistance; Flow Cytometry; Leukemia L1210; Methotrexate; Mice; Polyploidy; Vinblastine; Vinca Alkaloids; Vincristine; Vindesine | 1984 |
Karyotypic analysis of CCRF-CEM and drug-resistant cell lines with stable and unstable ploidy.
Topics: Chromosome Aberrations; Chromosomes, Human, Pair 8; Drug Resistance; Gene Deletion; Humans; Karyotyping; Leukemia, T-Cell; Methotrexate; Ploidies; Polyploidy; Tumor Cells, Cultured; Vincristine | 1993 |
A comparison of the propensity for gene amplification between near-tetraploid and near-diploid V79 clones resistant to 150 nM methotrexate.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line; Cricetinae; Diploidy; Drug Resistance; Gene Amplification; In Situ Hybridization, Fluorescence; Methotrexate; Microscopy, Confocal; Phenotype; Polyploidy; Tetrahydrofolate Dehydrogenase | 1996 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Fatal Outcome; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma, Large B-Cell, Diffuse; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Neoplastic Stem Cells; Palliative Care; Polyploidy; Prednisone; Procarbazine; Recurrence; Vincristine | 1998 |
Effect of drugs on chromosome structure.
Topics: Carcinogens; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Contraceptives, Oral; DNA; Down Syndrome; Female; Humans; Karyotyping; Leukocytes; Lysergic Acid Diethylamide; Methotrexate; Mitosis; Mutagens; Nutrition Disorders; Polyploidy; RNA; Teratogens; Trisomy | 1975 |
[Effects of Methotrexat on the chromosomes of a human fetus in vivo (author's transl)].
Topics: Abortion, Therapeutic; Blood Cells; Brain; Chromatids; Chromosome Aberrations; Chromosomes; Cytogenetics; Female; Fetus; Hodgkin Disease; Humans; Lung; Methotrexate; Mitosis; Polyploidy; Pregnancy; Pregnancy Complications; Skin | 1975 |
Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus.
Topics: Animals; Cell Line; Chromosomes; Diploidy; Drug Resistance; Fluorescent Dyes; Gene Amplification; Methotrexate; Mitosis; Nucleic Acid Hybridization; Plasmids; Polyploidy; Sister Chromatid Exchange; Tetrahydrofolate Dehydrogenase | 1989 |
Suppression of the avian sarcoma virus genome in hamster-transformed cells made resistant to 8-azaguanine.
Topics: Animals; Antigens, Viral; Avian Sarcoma Viruses; Azaguanine; Carbon Radioisotopes; Cell Division; Cell Fusion; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Chickens; Chromosome Mapping; Clone Cells; Cricetinae; Drug Resistance; Genotype; Glycine; Hypoxanthines; Methotrexate; Neoplasms, Experimental; Pentosyltransferases; Phenotype; Polyploidy; Thymidine | 1974 |
Selective cell survival and changes of marker properties during cryopreservation for up to 16 years.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Chromosomes; Clone Cells; Culture Techniques; Freezing; Histocompatibility Antigens; Humans; Lymphoma; Methotrexate; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Polyploidy; Sarcoma 180; Species Specificity; Time Factors; Tissue Preservation; Transplantation, Homologous | 1974 |
Cytological aberrations produced by methotrexate in mouse ascites tumours.
Topics: Animals; Cell Line; Chromatids; Chromosome Aberrations; Methotrexate; Mice; Mice, Inbred Strains; Mitosis; Neoplasms, Experimental; Polyploidy; Time Factors | 1972 |