Page last updated: 2024-08-25

methotrexate and Pancreatic Neoplasms

methotrexate has been researched along with Pancreatic Neoplasms in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199031 (43.06)18.7374
1990's24 (33.33)18.2507
2000's9 (12.50)29.6817
2010's7 (9.72)24.3611
2020's1 (1.39)2.80

Authors

AuthorsStudies
Adile, AA; Bakhshinyan, D; Berger-Becvar, A; de Araujo, ED; Deininger, MW; Fishel, ML; Gawel, JM; Geletu, M; Grimard, ML; Gunning, PT; Heaton, WL; Konieczny, SF; Luchman, HA; O'Hare, T; Raouf, YS; Shah, F; Shouksmith, AE; Singh, SK; Venugopal, C; Weiss, S1
Bai, C; Chen, L; Lin, S; Liu, Y; Liu, Z; Tian, X; Zeng, X1
Chang, LC; Lin, FC; Manoharan, D; Shan, YS; Sheu, HS; Su, WP; Wang, LC; Wu, LC; Yeh, CS1
Adelstein, SJ; Artignan, X; Balosso, J; Desruet, MD; Fagret, D; Gauchez, AS; Hoffmann, D; Kassis, AI; Rebischung, C; Stefani, L; Vincent, F; Vuillez, J; Wang, K; Zhang, H1
Bengrine-Lefevre, L; Chouaid, C; Olezac, AS; Papanikolaou, I1
Chan, S; Melia, W; Minchom, A; Shah, R1
Abolhassani, M; Baronzio, G; Behzadi, M; Campion, F; Fiorentini, G; Guais, A; Mainini, C; Montagnani, F; Sanders, E; Schwartz, L1
Azad, NA; Kern, SE; Patel, K; Yerram, SR1
Deschatrette, J; Ng-Bonaventure, K; Philippe, L; Wolfrom, C1
Choi, EW; Cusack, JC; Donahue, JM; Fuchs, BC; Kasuya, H; Kawasaki, H; Kulu, Y; Kuruppu, DK; Tanabe, KK1
Baba, Y; Hayashi, S; Ishikawa, T; Kamimura, T; Nomura, K; Oota, H; Yoshida, T1
NORCROSS, JW; SULLIVAN, RD; WATKINS, E1
SULLIVAN, RD; ZUREK, WZ1
Imaoka, S; Ishikawa, O; Nakaizumi, A; Ohigashi, H; Sasaki, Y; Uehara, H; Yamada, T; Yokayama, S1
Arai, K; Ema, T; Iwasaki, Y; Katayanagi, S; Maeda, Y; Takahashi, K; Takahashi, T; Yamaguchi, T1
Eibl, G; Jolly, CI; Narayanan, S; Patil, S1
Barkanov, AI; Itin, AB; Klimenkov, AA1
Benz, C; Cadman, E1
Chang, BK; Gutman, R1
Abe, M; Ichiba, K; Kuraishi, Y; Meguro, S; Mikouchi, S; Yoda, T1
Cocking, JB; Cwynarski, MT; Diffey, BL; Fox, CA; Hanley, J; Jackson, GA; Mallinson, CN; Rake, MO; Wass, VJ1
Banfi, L; Garelli, S; Schieppati, G; Valbonesi, M1
Itakura, M; Kobayashi, F; Matsuzaki, S; Muramatsu, C; Onami, S; Sato, T; Shiraishi, K; Simamura, K; Watanabe, M1
Chandrasekaran, B; Duch, DS; Kute, TE1
Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Masutani, S; Nakamori, S; Ohigashi, H; Sasaki, Y2
Chen, ZH; Savarese, TM; Zhang, H1
Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Iwanaga, T; Kabuto, T; Kameyama, M; Nakamori, S; Nakano, H; Ohigashi, H; Sasaki, Y; Tsuji, Y; Yasuda, T1
Ansari, R; Gonin, R; Loehrer, PJ; McClean, J; Miller, KD; Mortimer, J; Pletcher, W; Spiridonidis, CH; Weber, G1
Hashimoto, M; Kawasaki, T; Kikuyama, M; Kobayashi, Y; Murohisa, G; Shimizu, E; Souda, K; Suzuki, F; Tsugiki, M; Yoshimi, T1
Iwasaki, R; Kamano, T; Kobayashi, S; Matsumura, S; Ono, K; Sakamoto, K1
Atsumi, M; Hayashi, K; Konishi, Y; Maruyama, H; Nakatsuji, N; Shimamoto, K; Sugihara, S; Tsutsumi, M1
Chen, ZH; Olopade, OI; Savarese, TM1
Berns, T; Harstrick, A; Hiddemann, W; Köhne, CH; Preusser, P; Schmoll, HJ; Seeber, S; Strumberg, D; Wilke, H1
Fujita, M; Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Kuroda, C; Nakamori, S; Nakano, H; Ohigashi, H; Sasaki, Y; Yasuda, T1
Fujita, M; Furukawa, H; Hiratsuka, M; Hosomi, N; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Kuroda, C; Murata, K; Nakaizumi, A; Nakano, H; Ohigashi, H; Sasaki, Y; Uehara, H; Yasuda, T1
Kunii, Y; Masamune, R; Takahashi, N1
Angiona, S; Canaletti, R; Cavicchi, F; Contu, A; Di Costanzo, F; Gasperoni, S; Luppi, G; Olmeo, N; Pucci, F; Rodinò, C; Sdrobolini, A; Zironi, S1
Ishikawa, T; Matsui, S; Matsuki, H; Matsuzawa, J; Mita, Y; Sato, S; Tashiro, K; Tashiro, S1
Bruckner, HW; Evans, A; Kozuch, P; Petryk, M1
Cubilla, AL; Hajdu, SI1
Oberfield, RA1
Barkin, J; Bateman, J; Brooks, J; Chaffe, J; Douglass, HO; Frytak, S; Hahn, RG; Kalser, M; Knowlton, A; Lavin, PT; Lessner, H; Like, A; Livstone, E; Lokich, J; Mann-Kaplan, R; Milliron, S; Moertel, CG; O'Connell, MJ; Ramming, K; Redlhammer, D; Reitemeier, RJ; Rubin, J; Schein, PS; Schutt, AJ; Silverman, M; Spiro, H; Troner, M; Weiland, LH; Zamcheck, N1
Costanzi, JJ; Panettiere, FJ; Wolma, FJ1
Hartmann, D; Obrecht, JP1
Herman, T; Kim, E1
Hunstein, W; Rehn, K1
Nagy, A; Radulovic, S; Schally, AV; Szoke, B1
Taniki, T; Weber, G; Zhen, YS1
Kao, GD1
Fukuda, I; Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Masutani, S; Ohigashi, H; Sasaki, Y1
Pyrhönen, S; Valtonen, M1
Moroni, M; Nastasi, G; Porta, C; Spaghi, A1
Nagai, M; Nakamura, H; Olah, E; Prajda, N; Szekeres, T; Weber, G1
Barlow, JF; Cullinan, S; Foley, JF; Kardinal, CG; Krook, JE; Moertel, CG; Norris, BD; Schutt, AJ; Tschetter, LK; Wieand, HS1
Funovics, J; Ludwig, H; Mueller, C; Scheithauer, W1
Barkanov, AI; Itin, AB1
Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Iwanaga, T; Kabuto, T; Ohigashi, H; Sasaki, Y; Shibata, T; Yasuda, T1
Funovics, J; Grabner, G; Knoflach, P; Ludwig, H; Müller, C; Scheithauer, W; Zielinski, C1
Kimoto, Y2
Omote, Y1
Ishikawa, O; Iwanaga, T; Ohhigashi, H1
Cocconi, G; Missale, G; Pettenati, V1
Griffen, WO; Humphrey, L; Sosin, H1
Hahn, RG; Moertel, CG; Reitemeier, RJ1
Coltman, CA; Costanzi, JJ1
Chernik, NL; Olson, ME; Posner, JB1
Gazet, JC; Smith, R1
Lynch, RG; Tavassoli, FA1
Amiel, JL; Cattan, A; de Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Rosenfeld, C; Schlumberger, JR; Schneider, M; Schwarzenberg, L1
Porter, EA1

Reviews

5 review(s) available for methotrexate and Pancreatic Neoplasms

ArticleYear
[A case of retroperitoneal NHL with direct invasion to the liver, pancreas and gastric wall].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Humans; Leucovorin; Liver Neoplasms; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Invasiveness; Pancreatic Neoplasms; Prednisone; Remission Induction; Retroperitoneal Neoplasms; Stomach Neoplasms; Vincristine

1995
[A case of alpha-fetoprotein-producing pancreatic carcinoma--review of 41 cases reported in Japan].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1996, Volume: 93, Issue:12

    Topics: Adenocarcinoma; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Humans; Immunohistochemistry; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Stents

1996
Anaplastic Ki-1-positive large cell lymphoma of the pancreas: a case report and review of the literature.
    Japanese journal of clinical oncology, 1997, Volume: 27, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Humans; Lymphoma, Large-Cell, Anaplastic; Methotrexate; Middle Aged; Pancreatic Neoplasms; Peplomycin; Prednisolone; Vincristine

1997
Treatment of metastatic pancreatic adenocarcinoma: a comprehensive review.
    The Surgical clinics of North America, 2001, Volume: 81, Issue:3

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Irinotecan; Methotrexate; Pancreatic Neoplasms; Randomized Controlled Trials as Topic

2001
The prognosis and management of recurrent abdominal malignancies.
    Current problems in surgery, 1969

    Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Bile Duct Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Mechlorethamine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Palliative Care; Pancreatic Neoplasms; Prognosis; Rectal Neoplasms; Stomach Neoplasms; Thiotepa

1969

Trials

6 trial(s) available for methotrexate and Pancreatic Neoplasms

ArticleYear
Chemotherapy in pancreatic cancer: results of a controlled, prospective, randomised, multicentre trial.
    British medical journal, 1980, Dec-13, Volume: 281, Issue:6255

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Pancreatic Neoplasms; Prospective Studies; Random Allocation; Vincristine

1980
A phase II study of weekly oral methotrexate and zidovudine (AZT) in advanced adenocarcinoma of the pancreas and hepatocellular carcinoma.
    Investigational new drugs, 1996, Volume: 14, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Remission Induction; Zidovudine

1996
Modulation of fluorouracil by methotrexate, leucovorin, and cisplatin (M-FLP) in the treatment of advanced pancreatic cancer: a phase II study of the Italian Oncology Group for Clinical Research (GOIRC).
    American journal of clinical oncology, 2000, Volume: 23, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Immunologic Factors; Italy; Leucovorin; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Survival Rate; Treatment Failure

2000
Randomized phase II clinical trial of adriamycin, methotrexate, and actinomycin-D in advanced measurable pancreatic carcinoma: a Gastrointestinal Tumor Study Group Report.
    Cancer, 1978, Volume: 42, Issue:1

    Topics: Adult; Aged; Bone Marrow; Clinical Trials as Topic; Dactinomycin; Doxorubicin; Drug Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Remission, Spontaneous; Time Factors

1978
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
    Cancer, 1990, May-15, Volume: 65, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine

1990
[Chemotherapy of advanced pancreatic cancer with 5-fluorouracil, doxorubicin and high-dose methotrexate].
    Leber, Magen, Darm, 1988, Volume: 18, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms

1988

Other Studies

61 other study(ies) available for methotrexate and Pancreatic Neoplasms

ArticleYear
Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer.
    Journal of medicinal chemistry, 2019, 03-14, Volume: 62, Issue:5

    Topics: Animals; Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Disease Models, Animal; Histone Deacetylase Inhibitors; Humans; Hydrocarbons, Fluorinated; Hydroxamic Acids; Mice; Pancreatic Neoplasms; Sulfonamides

2019
Fatal myositis and spontaneous haematoma induced by combined immune checkpoint inhibitor treatment in a patient with pancreatic adenocarcinoma.
    BMC cancer, 2019, Dec-05, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Antineoplastic Agents, Immunological; Fatal Outcome; Hematoma; Humans; Ipilimumab; Male; Methotrexate; Myositis; Nivolumab; Pancreatic Neoplasms

2019
Synchronization of Nanoparticle Sensitization and Radiosensitizing Chemotherapy through Cell Cycle Arrest Achieving Ultralow X-ray Dose Delivery to Pancreatic Tumors.
    ACS nano, 2021, 05-25, Volume: 15, Issue:5

    Topics: Cell Cycle Checkpoints; Drug Delivery Systems; Humans; Methotrexate; Nanoparticles; Pancreatic Neoplasms; X-Rays

2021
First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.
    International journal of radiation biology, 2008, Volume: 84, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Antigens, Tumor-Associated, Carbohydrate; Brain Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Idoxuridine; Injections, Spinal; Iodine Radioisotopes; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Radiopharmaceuticals

2008
[Choriocarcinoma with pulmonary metastasis: diagnosis and treatment].
    Revue des maladies respiratoires, 2009, Volume: 26, Issue:7

    Topics: Antimetabolites, Antineoplastic; Biopsy; Choriocarcinoma; Choriocarcinoma, Non-gestational; Chorionic Gonadotropin; Diagnosis, Differential; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Pancreatic Neoplasms; Prognosis; Radiography, Thoracic; Remission Induction; Scalp; Skin; Skin Neoplasms; Tomography, X-Ray Computed

2009
An unusual case of pancreatic cancer with leptomeningeal infiltration.
    Journal of gastrointestinal cancer, 2010, Volume: 41, Issue:2

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Cytarabine; Drug Therapy, Combination; Fatal Outcome; Humans; Hydrocortisone; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Pancreatic Neoplasms

2010
Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cisplatin; Citrates; Deoxycytidine; Energy Metabolism; Female; Gemcitabine; Humans; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pancreatic Neoplasms; Thioctic Acid; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Urinary Bladder Neoplasms

2012
A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.
    Oncotarget, 2012, Volume: 3, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Monitoring; Female; Floxuridine; Fluorouracil; Immunoenzyme Techniques; Methotrexate; Mice; Mice, Nude; Pancreatic Neoplasms; Rats; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured

2012
Interaction between Gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Death; Drug Resistance, Neoplasm; Drug Synergism; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Melanoma, Experimental; Methotrexate; Mice; Pancreatic Neoplasms; Rats; Tetrahydrofolate Dehydrogenase; Xanthones

2013
Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis.
    Cancer gene therapy, 2013, Volume: 20, Issue:2

    Topics: Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Herpesvirus 1, Human; Humans; Irinotecan; Methotrexate; NF-kappa B; Oncolytic Virotherapy; Oncolytic Viruses; Pancreatic Neoplasms; Transcriptional Activation; Tumor Necrosis Factor-alpha; Virus Replication

2013
[A case of advanced gastric cancer with liver and intra-abdominal lymph node metastasis treated by hypertensive selective chemotherapy with pharmacokinetic modulating chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8

    Topics: Adenocarcinoma; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur

2003
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
    The New England journal of medicine, 1964, Feb-13, Volume: 270

    Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Erythrocyte Count; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Sulfobromophthalein; Transaminases; Uterine Cervical Neoplasms

1964
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
    Cancer chemotherapy reports, 1964, Volume: 37

    Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exfoliative; Equipment and Supplies; Floxuridine; Fluorouracil; Humans; Infusion Pumps; Infusions, Parenteral; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms; Testicular Neoplasms; Thyroid Neoplasms; Tongue Neoplasms; Toxicology

1964
Intra-arterial infusion chemotherapy with angiotensin-II for locally advanced and nonresectable pancreatic adenocarcinoma: further evaluation and prognostic implications.
    Annals of surgical oncology, 2003, Volume: 10, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Angiotensin II; Chi-Square Distribution; Female; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Prognosis; Statistics, Nonparametric; Survival Analysis; Vasoconstrictor Agents

2003
[A case of curatively resected gastric cancer through an effective response to chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Jejunostomy; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Invasiveness; Pancreatic Neoplasms; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms

2004
Evaluation of antimitotic activity of Rotula aquatica (Lour): a traditional herb used in treatment of cancer.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:9

    Topics: Allium; Antimetabolites, Antineoplastic; Boraginaceae; Cell Division; Chromatography, High Pressure Liquid; Folic Acid; Mass Spectrometry; Methotrexate; Mitotic Index; Pancreatic Neoplasms; Phytotherapy; Plant Extracts; Plant Roots; Steroids; Tannins

2004
[A method of radiation and combined treatment in inoperable cancer of the pancreas].
    Voprosy onkologii, 1984, Volume: 30, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Gamma Rays; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Pancreatic Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage; Radiotherapy, High-Energy; Vincristine

1984
Cytotoxicity of several chemotherapeutic agents in a human pancreatic cancer cell line (Colo-357).
    Cancer treatment reports, 1984, Volume: 68, Issue:2

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Doxorubicin; Drug Evaluation; Humans; Methotrexate; Mitomycins; Pancreatic Neoplasms; Time Factors

1984
Chemotherapy of pancreatic adenocarcinoma: initial report on two transplantable models in the Syrian hamster.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Cyclophosphamide; Disease Models, Animal; Fluorouracil; Guinea Pigs; Male; Mesocricetus; Methotrexate; Mitomycin; Mitomycins; Neoplasms, Experimental; Pancreatic Neoplasms; Vincristine

1982
Combination chemotherapy with 5-FU 1-(aminomethyl)-3-(2-chloroethyl)-3-nitrosourea (ACNU), and mitomycin (FUM) for carcinoma of the pancreas.
    Cancer treatment reports, 1982, Volume: 66, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Nimustine; Nitrosourea Compounds; Pancreatic Neoplasms

1982
Defective function of granulocytes in patients with cancer.
    Tumori, 1981, Oct-31, Volume: 67, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Granulocytes; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Uterine Neoplasms

1981
Synchronization of cells in the S phase of the cell cycle by 3'-azido-3'-deoxythymidine: implications for cell cytotoxicity.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Leukemia; Melanoma; Methotrexate; Pancreatic Neoplasms; S Phase; Tumor Cells, Cultured; Zidovudine

1995
[Evaluation of intra-arterial infusion chemotherapy and radical pancreatectomy in patients with locally advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:11

    Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Doxorubicin; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Neoplasm Invasiveness; Pancreatectomy; Pancreatic Neoplasms; Survival Rate

1993
Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy.
    Cancer research, 1996, Mar-01, Volume: 56, Issue:5

    Topics: Antimetabolites, Antineoplastic; Base Sequence; Carcinoma; Drug Resistance; Gene Deletion; Humans; Interferon-alpha; Interferon-beta; Methotrexate; Molecular Sequence Data; Pancreatic Neoplasms; Purine-Nucleoside Phosphorylase; Tumor Cells, Cultured

1996
[A case of non-resectable pancreatic cancer surviving more than 4 years by intra-arterial infusion chemotherapy with angiotensin-II].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11

    Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Pancreatic Neoplasms; Survivors

1996
[A case of gastric malignant lymphoma with perforation during chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Prednisolone; Rupture, Spontaneous; Splenic Neoplasms; Stomach Neoplasms; Stomach Rupture; Vincristine

1997
Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis.
    Molecular pharmacology, 1997, Volume: 52, Issue:5

    Topics: Adenosine; Antimalarials; Antimetabolites, Antineoplastic; Azaserine; Biomarkers, Tumor; Cell Count; Deoxyadenosines; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Methionine; Methotrexate; Pancreatic Neoplasms; Purine-Nucleoside Phosphorylase; Purines; RNA, Messenger; Thionucleosides; Tumor Cells, Cultured

1997
Modulation of 5-fluorouracil with methotrexate and low-dose N-(phosphonacetyl)-L-aspartate (PALA) is inactive in advanced pancreatic carcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Phosphonoacetic Acid

1997
[A case report of preoperative intra-arterial infusion chemotherapy for pancreatic head carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12

    Topics: Adenocarcinoma; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Vasoconstrictor Agents

1997
[A measure to continue intra-arterial infusion chemotherapy long-term for locally advanced pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:9

    Topics: Angiotensin II; Antimetabolites, Antineoplastic; Catheters, Indwelling; Drug Administration Schedule; Female; Heparin; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Methotrexate; Middle Aged; Pancreatic Neoplasms

1998
[A case of unresectable pancreatic cancer responding to MTX/5-FU sequential therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Quality of Life

1999
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with angiotensin-II and administration of tegafur/uracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:4

    Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Tegafur; Uracil

2001
Islet cell carcinoma of the pancreas.
    Archives of pathology, 1975, Volume: 99, Issue:4

    Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Hyperglycemia; Hypoglycemia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Streptozocin

1975
Recent trends in chemotherapy of solid tumors.
    The Medical clinics of North America, 1975, Volume: 59, Issue:2

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms

1975
Combination chemotherapy for advanced pancreatic carcinoma.
    Texas medicine, 1979, Volume: 75, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Vincristine

1979
[Current state of therapy for gastrointestinal tumors].
    Schweizerische medizinische Wochenschrift, 1978, Sep-02, Volume: 108, Issue:35

    Topics: Carmustine; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Methotrexate; Pancreatic Neoplasms; Prognosis; Remission, Spontaneous; Stomach Neoplasms; Vincristine

1978
Burkitt's lymphoma in an American youth: usefulness of radionuclide imaging in diagnosis and measuring the effects of treatment.
    Clinical pediatrics, 1977, Volume: 16, Issue:9

    Topics: Adolescent; Burkitt Lymphoma; Cyclophosphamide; Humans; Liver Neoplasms; Male; Methotrexate; Pancreatic Neoplasms; Prednisone; Radionuclide Imaging; Thyroid Neoplasms; Vincristine

1977
[Tumor-induction through cytostatic agents in man].
    Deutsche medizinische Wochenschrift (1946), 1975, Jan-24, Volume: 100, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Carcinogens; Cyclophosphamide; Humans; Leukemia, Myeloid; Lung Neoplasms; Melphalan; Methotrexate; Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Triaziquone; Urinary Bladder Neoplasms

1975
Cytotoxic analog of somatostatin containing methotrexate inhibits growth of MIA PaCa-2 human pancreatic cancer xenografts in nude mice.
    Cancer letters, 1992, Mar-15, Volume: 62, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Division; Cell Line; Growth Hormone; Humans; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Octreotide; Organ Size; Pancreatic Neoplasms; Receptors, Neurotransmitter; Receptors, Somatostatin

1992
[Evaluation of radiation therapy combined with intra-arterial infusion chemotherapy in patients with non-resectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Pancreatic Neoplasms; Radiotherapy, High-Energy; Retrospective Studies; Survival Rate

1992
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells.
    Oncology research, 1992, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine

1992
Chemotherapy for pancreatic carcinoma.
    Lancet (London, England), 1991, Jan-19, Volume: 337, Issue:8734

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Survival Rate

1991
[Hepatic arterial infusion chemotherapy and loco-regional treatment and irradiation of pancreas tumor in non-resectable pancreas cancer with liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Administration, Oral; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Radiotherapy, High-Energy

1991
Response to doxorubicin/methotrexate/fluorouracil in advanced adenocarcinoma of pancreas or biliary tract.
    Lancet (London, England), 1990, Jul-14, Volume: 336, Issue:8707

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Prognosis

1990
Doxorubicin/methotrexate/fluorouracil in advanced pancreatic cancer.
    Lancet (London, England), 1990, Dec-08, Volume: 336, Issue:8728

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms

1990
AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells.
    Cancer communications, 1991, Volume: 3, Issue:4

    Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Methotrexate; Ovarian Neoplasms; Pancreatic Neoplasms; Rats; Thymidine; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine

1991
Sequential high-dose methotrexate, 5-fluorouracil, and doxorubicin for treatment of advanced pancreatic cancer.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms

1990
[Chemoradiation treatment of pancreatic cancer].
    Meditsinskaia radiologiia, 1985, Volume: 30, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Pancreatic Neoplasms; Radiotherapy Dosage; Time Factors; Vincristine

1985
[Preventive effects of intra-arterial infusion chemotherapy of liver metastasis in non-resectable pancreatic cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Alprostadil; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Portal Vein

1989
[Antitumor effect of interferons with chemotherapeutic agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Cell Line; Cells, Cultured; Cisplatin; Drug Therapy, Combination; Fluorouracil; Humans; Interferon Type I; Interferon-gamma; Methotrexate; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms

1986
[Combined effect of interferons alpha, beta and gamma on tumor growth in vitro].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Animals; Cell Line; Cells, Cultured; Drug Therapy, Combination; Fluorouracil; Humans; Interferon Type I; Interferon-gamma; Methotrexate; Mice; Pancreatic Neoplasms; Stomach Neoplasms

1986
[An experimental attempt to potentiate therapeutic effects of combined use of pulsing magnetic fields and antitumor agents].
    Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:8

    Topics: Adenocarcinoma; Animals; Cell Division; Combined Modality Therapy; Cricetinae; DNA, Neoplasm; Electromagnetic Phenomena; Leukemia, Experimental; Magnetic Field Therapy; Male; Methotrexate; Mitomycin; Mitomycins; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured

1988
[Intra-arterial infusion chemotherapy for non-resectable pancreatic cancer using angiotensin-II and prostaglandin-E1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Adult; Aged; Alprostadil; Angiography; Angiotensin II; Catheterization; Drug Administration Schedule; Female; Humans; Infusions, Intra-Arterial; Male; Methotrexate; Middle Aged; Pancreas; Pancreatic Neoplasms; Prognosis; Prostaglandins E; Regional Blood Flow

1985
[Comparison of several different methods of antiblastic therapy in advanced carcinomas of the digestive system].
    Il Cancro, 1974, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Esophageal Neoplasms; Fluorouracil; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Methotrexate; Pancreatic Neoplasms; Vincristine

1974
Oral methotrexate therapy of gastrointestinal carcinoma.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:2

    Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Liver Neoplasms; Methotrexate; Palliative Care; Pancreatic Neoplasms; Stomach Neoplasms

1970
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors.
    Cancer, 1969, Volume: 23, Issue:3

    Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Pancreatic Neoplasms; Pharyngeal Neoplasms; Prognosis; Sarcoma; Sarcoma, Synovial; Vincristine

1969
Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study.
    Archives of neurology, 1974, Volume: 30, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Autopsy; Brain Neoplasms; Breast Neoplasms; Cerebral Cortex; Cranial Nerves; Female; Headache; Humans; Injections, Spinal; Intracranial Pressure; Lung Neoplasms; Lymphoma; Male; Melanoma; Meninges; Mental Disorders; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Seeding; Pancreatic Neoplasms; Sarcoma; Spinal Nerve Roots

1974
Intra-arterial chemotherapy for patients with inoperable carcinoma of the pancreas.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:11

    Topics: Catheterization; Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Jaundice; Methods; Methotrexate; Pain; Pancreatic Neoplasms; Vincristine

1974
Occult adenocarcinoma of the pancreas in a 17-year-old patient with immunosuppressed leukemia.
    Gastroenterology, 1974, Volume: 66, Issue:5

    Topics: Adenocarcinoma; Adolescent; Age Factors; Autopsy; Brain Neoplasms; Cyclophosphamide; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Neoplasms, Multiple Primary; Pancreas; Pancreatic Neoplasms; Prednisone; Vincristine

1974
[A new combination of methotrexate and folinic acid for cancer treatment (acute leukemia and solid tumors)].
    La Presse medicale, 1969, Mar-01, Volume: 77, Issue:11

    Topics: Agranulocytosis; Antineoplastic Agents; Breast Neoplasms; Female; Hemangiosarcoma; Hodgkin Disease; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Osteosarcoma; Pancreatic Neoplasms; Radiography; Rectal Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Thrombocytopenia

1969
Carcinoma of the pancreas.
    The New Zealand medical journal, 1970, Volume: 71, Issue:456

    Topics: Adult; Age Factors; Aged; Barium Sulfate; Bilirubin; Carcinoma; Cyclophosphamide; Duodenum; Female; Glucocorticoids; Humans; Jaundice; Laparotomy; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Sex Factors

1970