methotrexate has been researched along with Palmoplantaris Pustulosis in 1799 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 670 (37.24) | 18.7374 |
| 1990's | 169 (9.39) | 18.2507 |
| 2000's | 247 (13.73) | 29.6817 |
| 2010's | 494 (27.46) | 24.3611 |
| 2020's | 219 (12.17) | 2.80 |
| Authors | Studies |
|---|---|
| Clary, DD; Fanciullo, J; Kiani, R; Reid, AT | 1 |
| Cerroni, L; Kränke, B; Sadoghi, B; Weger, W | 1 |
| Gmeiner, T; Grželj, J; Marko, PB; Marovt, M; Mlinarič-Raščan, I; Šmid, A | 2 |
| Chhabra, M; Kumar, S; Rashid, M; Venkataraman, R; Zuber, M | 1 |
| Higashi, Y; Imafuku, S; Katayama, E; Ohata, C; Saito, K; Tsuruta, N; Yonekura, K | 1 |
| Albrecht, LE; Gooderham, MJ; Lynde, CW; Papp, KA; Raymond, MA | 1 |
| Akiki, D; El Hage, S; El Masri, J; Roustom, M | 1 |
| Kuo, G; Lin, MS; Lin, YS; Ting, SW; Ting, SY | 1 |
| Jamil, A; Khor, YH; Lee, CK; Lee, JHM; Loo, CH; Tan, WC | 1 |
| Kumsa, SM; Tadesse, TA; Woldu, MA | 1 |
| Fu, S; Lai, R; Liu, Z; Lu, Y; Luo, W; Wang, Y; Xu, Y | 1 |
| Loft, N; Møller, DL; Nielsen, SD; Ostrowski, SR; Skov, L; Todberg, T | 1 |
| Deng, H; Fang, X; Han, L; Hu, Y; Huang, Q; Wang, B; Wu, S; Yan, K; Yang, K; Yawalkar, N; Zhang, Z; Zheng, Z | 1 |
| Chaowattanapanit, S; Choonhakarn, C; Julanon, N; Limpawattana, P | 1 |
| Beukelman, T; Son, MB; Sullivan, E; Zhao, Y | 1 |
| Alessandrini, A; Bruni, F; D'Altobrando, A; Ferrari, T; Iorizzo, M; Piraccini, BM; Starace, M | 1 |
| Baskaev, KK; Denisova, EV; Korsunskaya, IM; Sobolev, VV; Voron'ko, OE | 1 |
| Chen, Y; Gu, Y; Liu, Y; Wang, Y; Wang, Z; Xiang, X; Xu, Z; Zhao, M | 1 |
| Busard, C; de Jong, E; de Kort, W; de Rie, M; de Vries, A; Hutten, B; Lambert, J; Menting, S; Musters, A; Ouwerkerk, W; Prens, E; Rispens, T; Spuls, P; van Bezooijen, SJ; van den Reek, J; van der Kraaij, G; van Doorn, M | 1 |
| Banga, AK; Garimella, HT; German, CL; Vora, D | 1 |
| Alakad, R; Atef, H; Eldeeb, F; Nassar, A | 1 |
| Abad, ME; Akman-Karakas, A; Appelen, D; Araujo, RR; Ayanlowo, O; Azimi, SZ; Babic, LT; Balak, D; Barber, K; Boonen, HPJ; Brajac, I; Bylaite-Bucinskiene, M; Calzavara-Pinton, P; Cárdenas Rojas, PJ; Carija, A; Carretero, G; Castro, C; Castro-Ayarza, JR; Ceovic, R; Cetkovska, P; Chandrashekar, L; Choon, SE; Chosidow, O; Claréus, BW; Colombo, EP; Conrad, C; Correa, CC; Csányi, I; da Cruz Costa, SA; Damiani, G; Danespazhooh, M; de Jong, EMGJ; de la Cruz, C; de la Cueva, P; de Oliveira, MFSP; de Rie, MA; de Souza Sittart, JA; Del-Río, R; Doss, N; Drvar, DL; Dutil, M; Echeverría, CM; Egeberg, A; El Gamal, E; El-Sayed, MH; Fábos, B; Fardet, L; Félix, PAO; Fernandez-Peñas, P; Ferran, M; Ferrándiz, C; Firooz, A; Fougerousse, AC; Foulkes, A; Franco, MD; Frez, ML; García-Doval, I; Gebauer, KA; Ghislain, PD; Gisondi, P; Gomez, LC; Gómez-Flores, M; Gonçalo, M; Gonzalez, C; Gonzalez, GO; Gooderham, MJ; Goujon, C; Grewal, P; Griffiths, CEM; Grozdev, I; Gulin, SJ; Gulliver, W; Gyulai, R; Handa, S; Handjani, F; Holló, P; Hong, CH; Horváth, B; Hsiao, JP; Huldt-Nystrøm, T; Hunter, HJA; Hurtová, T; Ingram, JR; Iversen, L; Janmohamed, SR; Jullien, D; Kaštelan, M; Khobzei, K; Kim, DH; Kolalapudi, SA; Krisztián, G; Krnjevic-Pezic, G; Kui, R; Kumar, AS; Laffitte, E; Lafuente-Urrez, RF; Lambert, JLW; le Cleach, L; Lebwohl, M; Lecluse, L; Leonidze, T; Liu, TY; Llamas-Velasco, M; Luna, PC; Mahé, E; Mahil, SK; Maldonado-García, C; Mälkönen, T; Marchesi, C; Margasin, SM; Marrón, SE; Massari, LP; Matlock, BH; Maul, JT; Maul, LV; Menting, SP; Middelkamp-Hup, MA; Misery, L; Moussa, IO; Muresanu, LI; Nicolopoulos, J; Novoa, FD; Oakley, A; Olszewska, M; Oon, HH; Pellerano, G; Polic, MV; Prinz, JC; Puig, L; Rademaker, M; Ramam, M; Ramos, AMC; Reciné, TR; Reich, K; Riad, H; Romiti, R; Salleras I Redonnet, M; Sanchez, JL; Sator, P; Schejtman, AA; Schram, ME; Seyger, MMB; Sharma, VK; Sikora, M; Silverberg, NB; Skov, L; Sonkoly, E; Spuls, PI; Törocsik, D; Torres, T; Trcko, K; Turchin, I; Urbancek, S; Valenzuela, F; van den Reek, JMPA; van der Kraaij, GE; van Doorn, M; van Huizen, AM; Varela, P; Velásquez-Lopera, MM; Veldkamp, W; Vender, R; Vestergaard, C; Vilarrasa, E; Vílchez-Márquez, F; Warren, RB; Weightman, W; Weinberg, JM; Wells, J; Willaert, F; Wiseman, MC; Wong, TW; Yawalkar, N; Zargari, O; Zheng, M | 1 |
| Agostini, SBN; Alves, CO; Bernardes, MTCP; Carvalho, FC; da Silva, LP; Gonçalves, RV; Novaes, RD; Pereira, GR | 1 |
| Cordoro, KM; Ornelas, J | 1 |
| Capalbo, E; Cartocci, A; Cinotti, E; Cortonesi, G; Orsini, C; Rubegni, P; Trovato, E | 1 |
| Ariane, M; Mahé, E | 1 |
| Armeni, P; Bellinato, F; Geat, D; Girolomoni, G; Gisondi, P; Maurelli, M | 1 |
| Deng, H; Fang, X; Guo, M; Han, L; Huang, Q; Meng, Q; Wang, B; Wu, S; Yan, K; Yang, K; Yawalkar, N; Zhang, Z; Zheng, Z; Zhu, J | 1 |
| Cha, X; Chen, Y; Lai, B; Tao, T; Wang, J; Wang, W; Xiao, W | 1 |
| Alinia, H; Cardwell, LA; Cline, A; Feldman, SR; Huang, WW; Tull, R; Unrue, EL | 1 |
| Livesey, A; Raahimi, M; Sheppeard, R | 1 |
| Jendoubi, F; Masson Regnault, M; Paul, C; Shourick, J; Tauber, M | 1 |
| Altunay, IK; Erdem, Y; Ozkur, E; Tuncel, D; Ugurer, E | 1 |
| Bognar, K; Broder, MS; Chang, E; Desai, P; Husni, E; Kaplan, D; Khilfeh, I; Paydar, C; Richter, S; Yan, J | 1 |
| Patel, NP | 1 |
| Afach, S; Chaimani, A; Doney, L; Dressler, C; Garcia-Doval, I; Hua, C; Hughes, C; Le Cleach, L; Naldi, L; Sbidian, E | 1 |
| Bronckers, IMGJ; Bruins, FM; De Jong, EMGJ; Groenewoud, HMM; Seyger, MMB; Van Acht, MR | 1 |
| Han, L; He, H; Huang, Q; Meng, Q; Wang, ZC; Xu, JX; Yan, KX; Yawalkar, N; Zhang, ZH; Zhou, H; Zhu, HW | 1 |
| Chen, M; Dong, Z; Du, Y; Wang, F; Yan, Q | 1 |
| Abdelmeniem, IM; El Eryan, IM; Fouda, I; Nofal, A; Omar, SS | 1 |
| Dogra, S; Handa, S; Kumar, S; Narang, T; Singh, N | 1 |
| Akinde, M; Amy de la Bretêque, M; Bachelerie, M; Bachelez, H; Beauchet, A; Bellissen, A; Belloni Fortina, A; Bourrat, E; Brzezinski, P; Bursztejn, AC; Chiriac, A; Di Lernia, V; Epishev, R; Flohr, C; Lasek, A; Lesiak, A; Luca, C; Luna, PC; Mahé, E; Mahil, SK; Mallet, S; Maruani, A; McPherson, T; Murashkin, N; Neri, I; Smith, CH; Sonkoly, E; Steff, M; Thomas, J; Topkarci, Z; Torres, T; van den Reek, JMPA; Vidaurri de la Cruz, H; Zafiriou, E; Zitouni, J | 1 |
| Alt, C; Fink, C; Kilian, S; Schäkel, K; Schank, TE; Sies, K | 1 |
| Desai, RJ; Jin, Y; Kim, SC; Krueger, W; Landon, JE; Liede, A | 1 |
| Abhishek, A; Altmann, DM; Appelbe, D; Barber, V; Bluett, J; Boyton, RJ; Brooks, T; Coates, LC; Cook, JA; Cureton, L; Eldridge, L; Francis, A; Julier, P; McKnight, Á; Nguyen-Van-Tam, JS; Peckham, N; Rombach, I; Valdes, AM; Williams, HC | 1 |
| Chrobok, V; Dědková, J; Kašparová, P; Podrazilová, L; Rob, F; Školoudík, L | 1 |
| Baraldi, C; Patrizi, A; Savoia, F; Tabanelli, M; Zago, S | 1 |
| Bogdanos, DP; Dardiotis, E; Mavropoulos, A; Tsiogkas, SG; Zafiriou, E | 1 |
| Krebs, B; Menter, AM; Valdecantos, WC; Weiss, J; Zema, CL | 1 |
| Hsieh, CY; Tsai, TF | 1 |
| Darbasizadeh, B; Hashemi, S; Moghimi, HR; Mortazavi, SA | 1 |
| Chhabra, N; Choudhary, R; Gupta, AK; Singh, A | 1 |
| Mar, VJ; Wang, C; Wluka, AE; Wolfe, R; Yan, MK | 1 |
| Atwa, D; El Gayar, MA; Girgis, G; Marie, L | 1 |
| Bahuguna, A; Das, P; Sapra, D; Singh, GK | 1 |
| Chang, YT; Chou, YJ; Pan, TY; Wu, CY | 1 |
| Chen, S; Shi, Y; Tong, X; Wang, H; Wu, C; Zhao, Z | 1 |
| Ajgeiy, KK; Egeberg, A; Harboe, ZB; Liljendahl, MS; Loft, N; Møller, DL; Nielsen, SD; Rasmussen, MK; Rezahosseini, O; Skov, L | 1 |
| Aubert, H; Balguerie, X; Barbarot, S; Barthélémy, H; Beauchet, A; Boralevi, F; Di Lernia, V; Girard, C; Hadj-Rabia, S; Mahé, E; Mallet, S; Martin, L; Mazereeuw-Hautier, J; Phan, A; Phan, C; Piram, M; Severino-Freire, M; Zitouni, J | 1 |
| Cifuentes-González, C; de-la-Torre, A; Peña-Pulgar, LF; Pineda-Sierra, JS; Rojas-Carabali, W | 1 |
| Aubin, F; Gallais-Sérézal, I; Toussirot, E | 1 |
| Chen, Y; Deng, H; Deng, J; Deng, Y; Fang, X; Han, L; Huang, R; Lu, C; Qiu, Q; Roy, B; Shang, X; Yan, Y; Yao, D; Ye, S; Zheng, G | 1 |
| Chen, YJ; Dong, RJ; Kuang, YQ; Li, YY; Lu, YW; Shi, N; Wang, HM; Yang, LH | 1 |
| Imafuku, S; Sato, E; Takano-Kawasaki, S; Yamaguchi, K | 1 |
| Bautista Molano, W; Bisoendial, R; Candia, L; Casasola Vargas, JC; Ezeonyeji, A; FitzGerald, O; Goldenstein-Schainberg, C; Grazio, S; Gudu, T; Gutierrez Urena, SR; Korotaeva, TV; Leung, YY; Lindqvist, U; Malliotis, N; Meghnathi, B; Miranda, JRS; Mody, GM; Möller, B; Olsder, W; Pedersen, SJ; Perez-Alamino, R; Pineda, C; Prasad, R; Raffayova, H; Richette, P; Rohekar, S; Ruderman, EM; Simon, D; Soriano, ER | 1 |
| Ashforth, G; Ouellette, S; Razi, S; Shah, R; Wassef, C | 1 |
| Bouma, G; Bulatović Ćalasan, M; de Bruin-Weller, MS; de Jonge, R; Fidder, HH; Hebing, RCF; Heymans, MW; Nurmohamed, MT; Tekstra, J; van de Meeberg, MM; van den Bemt, B | 1 |
| Benites, E; Carrillo, E; Heras, M | 1 |
| Chen, M; Chen, W; Chen, X; Kuang, Y; Liu, P; Lu, Y; Lv, C; Mao, M; Yan, K; Zhu, W | 1 |
| Contri, RV; Frank, LA; Gomes, GS; Guterres, SS; Longhi, MS; Pohlmann, AR | 1 |
| Almirol, BJQ; de Guzman, DC; Dofitas, BL; Frez, MLF; Guce, K; Kimwell, MJM; Malaluan, MJQ; Mendoza, CG; Onda, AJM; Rivera, FD | 1 |
| Jabbour, R; Kaikati, J; Khater, JA; Skaff, S; Tomb, R | 1 |
| Abhishek, A; Aithal, GP; Ala, A; Aspinall, RJ; Atallah, E; Burden-Teh, E; Crooks, C; Grove, JI; Hutchinson, D; Jordan, KM; Moreea, S; Murphy, R | 1 |
| Al-Sofi, RF; Armenteros, JJA; Bundgaard, H; Fogh, K; Frikke-Schmidt, R; Garred, P; Hamm, SR; Hansen, CB; Hasselbalch, RB; Heftdal, LD; Hilsted, L; Iversen, K; Kvist-Hansen, A; Madsen, JR; Møller, DL; Nielsen, SD; Ostrowski, SR; Pérez-Alós, L; Pries-Heje, MM; Skov, L; Sørensen, E; Zachariae, C | 1 |
| Onuora, S | 1 |
| Egeberg, A; Gillstedt, M; Kristensen, K; Polesie, S; Pottegård, A; Schmidt, SAJ | 1 |
| Glynn, RJ; Jin, Y; Merola, JF; Oduol, T; Savage, TJ; Schneeweiss, MC; Schneeweiss, S; Schoder, K; Sidbury, R; Wyss, R | 1 |
| Carrascosa, JM | 1 |
| Aspinall, RJ; Hamilton, J; Livesey, A; Raahimi, MM; Shipman, AR | 1 |
| Alabas, OA; Bewley, A; Griffiths, CEM; Hampton, PJ; Laws, PM; Lunt, M; Mason, KJ; Owen, CM; Reynolds, NJ; Smith, CH; Warren, RB; Yiu, ZZN | 1 |
| Blanchard, I; Kodali, N; Kunamneni, S; Lebwohl, MG | 1 |
| Jiang, D; Li, J; Lyu, Y; Wu, D; Xin, X; Yang, L; Yin, L; Zhou, Y; Zhu, Y | 1 |
| Bi, D; Du, H; Liu, H; Liu, P; Liu, Y; Qu, F; Tao, J; Wu, J; Xiao, W; Xie, Y; Zhang, L; Zhu, J | 1 |
| Caldarola, G; Chiricozzi, A; De Luca, E; De Simone, C; Mariani, M; Peris, K | 1 |
| Becker, JC; Dittmer, U; Fiedler, M; Hölsken, S; Krefting, F; Lodde, GC; Placke, JM; Schadendorf, D; Schneider, L; Sondermann, W; Ugurel, S | 1 |
| Busard, CI; de Jong, EMGJ; de Vries, A; Lambert, J; Menting, SP; Ouwerkerk, W; Prens, EP; Rispens, T; Spuls, PI; van den Reek, JMPA; van der Kraaij, GE; van Doorn, MBA; van Huizen, AM | 1 |
| Chang, YC; Chen, CB; Chen, WT; Chung, WH; Hui, RC; Wang, CW; Wang, CY | 1 |
| Al-Nemrawi, NK; Alzoubi, KH; Khafajah, AS | 1 |
| Callaghan, G; Lyons, D; Murray, G; Roche, M; Ryan, J | 1 |
| Alabas, OA; Griffiths, CEM; Lunt, M; Mason, KJ; Smith, CH; Warren, RB; Yiu, ZZN | 1 |
| Girolomoni, G; Gisondi, P; Maurelli, M | 1 |
| Adiay, C; Akin Cakici, O; Apti Sengun, O; Ay, P; Enul, H; Ergun, T; Haklar, G; Hosgoren Tekin, S; Seckin, D; Sili, U; Yilmaz, S | 1 |
| Brueck, N; Dressler, F; Fasshauer, M; Foell, D; Horneff, G; Hospach, T; Hufnagel, M; Klein, A; Kuemmerle-Deschner, JB; Onken, N; Zimmer, A | 1 |
| Carrero, JJ; Krantz, Å; Lysell, J; Mazhar, F; Schalin, L; Yang, Y | 1 |
| Abbad-Jaime de Aragon, C; Berna-Rico, E; Gonzalez-Cantero, A; Perez-Bootello, J | 1 |
| Thomas, SE; van den Reek, JMPA | 1 |
| Afach, S; Chaimani, A; Garcia-Doval, I; Guelimi, R; Hua, C; Hughes, C; Kinberger, M; Le Cleach, L; Naldi, L; Sbidian, E | 1 |
| Baran, P; Ford, JP; Kamerow, HN; Patel, AB; Vanden Heuvel, JP; Zhou, S | 1 |
| Bandidniyamanon, W; Chaiyabutr, C; Charatcharoenwitthaya, P; Chularojanamontri, L; Griffiths, CEM; Likittanasombat, S; Panjapakkul, W; Pruksaeakanan, C; Wongdama, S | 1 |
| Stone, C; Taylor, DR | 1 |
| Smith, CR | 1 |
| Anwar, I; Essam, M; Komy, ME; Mohammed, RHA; Shehab, H | 1 |
| Han, L; Huang, Q; Wang, B; Wang, Z; Yan, K; Yang, W; Yao, Y; Yawalkar, N; Zhang, Z | 1 |
| Chiu, TM; Huo, AP; Leong, PY; Wei, JC | 1 |
| Arias-de la Rosa, I; Barbarroja, N; Barranco, A; Collantes-Estévez, E; Cuesta-López, L; Escudero-Contreras, A; Gahete, MD; Herman-Sánchez, N; López-Medina, C; López-Montilla, MD; López-Pedrera, C; Lucendo, AJ; Navarro, P; Ortiz-Buitrago, P; Pérez-Sánchez, C; Ruiz-Ponce, M | 1 |
| Anzengruber, F; Djamei, V; Drach, M; Häusermann, P; Maul, JT; Navarini, AA; Papageorgiou, K; Yawalkar, N | 1 |
| Bahramizadeh, M; Esmaily, H; Golmohammadzadeh, S; Hatamipour, M; Jafari, MR; Jafarian, AH; Kiafar, B; Moosavian, SA; Nikpoor, AR; Rezaeemehr, Z | 1 |
| Damiani, G | 1 |
| Aggarwal, G; Chandra, A; Manchanda, S; Narula, A | 1 |
| Bulut, H; Engin, B; Gökalp, E; Kutlubay, Z; Özkoca, D; Serdaroğlu, S; Songür, A; Tanakol, A; Tüzün, Y; Vehid, HE | 1 |
| Ståhle, M; Svedbom, A | 1 |
| deShazo, R; Fakharzadeh, S; Galindo, C; Goyal, K; Kalia, S; Krishnasamy, S; Krueger, G; Langholff, W; Langley, RG; Soltani-Arabshahi, R; Srivastava, B; Ståhle, M | 1 |
| Andreadou, I; Ikonomidis, I; Kapniari, I; Katsimbri, P; Loukeri, E; Makavos, G; Papadavid, E; Parissis, J; Pavlidis, G; Rafouli-Stergiou, P; Theodoropoulos, K; Thymis, J; Triantafyllidi, H; Tsoumani, M; Varoudi, M | 1 |
| Ashcroft, DM; Burden, AD; Griffiths, CEM; Lunt, M; Mason, KJ; McElhone, K; Rungapiromnan, W; Rutter, MK; Warren, RB | 1 |
| Schmutz, JL | 1 |
| Carneiro, GP; Duarte, AA; Jesus, LCB; Murari, CM | 1 |
| Du, H; Lan, J; Li, Y; Liu, P; Tao, J; Zhang, L; Zhu, J | 1 |
| Akdis, CA; Boyman, O; Hafner, J; Impellizzieri, D; Kolios, AGA; Kurzbach, D; Nguyen, TT; Nilsson, J; Özcan, A; Sahin, D; Tan, G; Yawalkar, N | 1 |
| Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Farley Prater, EA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Wong, EB; Wu, JJ | 1 |
| Chen, F; Ding, Y; Liu, N; Wang, Y; Zheng, J | 1 |
| Boggs, J; Collins, S; Feighery, C; Hollywood, A; O'Keeffe, C | 1 |
| Lim, YL; Toh, JJ; Yew, YW | 1 |
| Gabriel, A; Gogler-Piglowska, A; Kupczak, M; Michalski, M; Mielanczyk, A; Mielanczyk, Ł; Mrowiec, K; Neugebauer, D; Scieglinska, D; Skonieczna, M | 1 |
| Chen, JS; Chen, M; Cui, PG; Fang, H; Gao, XH; Gu, J; Guo, ZP; Jin, HZ; Lai, W; Li, W; Li, YZ; Liu, LF; Liu, XM; Lyu, CZ; Pang, XW; Shi, YL; Song, ZQ; Sun, Q; Wang, G; Xie, HF; Xu, JH; Yu, C; Zhang, W; Zhao, NQ; Zheng, M | 1 |
| Bélanger, A; Gendreau, I; Grenier, A; Legault, J; Pichette, A; Pouliot, R; Simard, F | 1 |
| Bavaharan, B; Kawali, A; Mahendradas, P; Mohan, A; Sanjay, S; Shetty, B | 1 |
| Curman, P; Krynitz, B; Lapins, J; Radros, N; Wikström, JD | 1 |
| Montanez-Wiscovich, ME; Shivers, L | 1 |
| Andanooru Chandrappa, NK; Channakeshavaiah Ravikumar, B; Rangegowda, SM | 1 |
| Gillstedt, M; Osmancevic, A; Paoli, J; Polesie, S | 1 |
| Alexopoulos, A; Belazarian, L; Blume-Peytavi, U; Bronckers, IMGJ; Cordoro, KM; Hogeling, M; Holland, K; Kievit, W; Lambert, J; Lara-Corrales, I; Mahé, E; Mrowietz, U; Murphy, R; Paller, AS; Puig, L; Seyger, MMB; Siegfried, E; Szalai, Z; Tollefson, MM; Tom, WL; Vleugels, RA; West, DP; Zachariae, C | 1 |
| Fleischer, AB; Muddasani, S | 1 |
| Balighi, K; Daneshpazhooh, M; Mahmoudi, H; Tavakolpour, S | 1 |
| Silverberg, JI; Singh, P | 1 |
| Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Prater, EF; Rahimi, RS; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Tapper, EB; Wong, EB; Wu, JJ | 1 |
| Müller, S; Schultes, D; Wilsmann-Theis, D | 1 |
| Egeberg, A; Haugaard, JH | 1 |
| Cappelli, LC; Demehri, S; Gelber, AC; Ponor, IL; Wright, SM | 1 |
| Alqarni, AM; Zeidler, MP | 1 |
| Augustin, M; Mrowietz, U; Radtke, MA; Reich, K; Rustenbach, SJ; Sorbe, C; Von Kiedrowski, R; Weckbecker, J | 1 |
| Chen, M; Chen, W; Chen, X; Kuang, Y; Liu, P; Lu, Y; Lv, C; Qin, Q; Yan, K; Zhang, M; Zhu, W | 1 |
| Ahmed, SH; El Saied, ARA; El-Hamd, MA; Hegazy, EM; Ibrahim, HM | 1 |
| Etesami, I; Fazlolahi, S; Ghiasi, M; Kashiri, A; Khosravi, D; Lajevardi, V | 1 |
| Alam, M; Ara, S; Khan, I; Mowla, MR | 1 |
| Choudhary, P; Ghiya, BC; Mehta, RD; Sharma, D | 1 |
| Abu-Farsakh, S; Al-Judaibi, B; Aranez, J; Cheong, J; Kyi, K; Laryea, M; Park, S; Whitney-Miller, C | 1 |
| Aickara, D; Bashyam, AM; Feldman, SR; Pichardo, RO | 1 |
| Chen, M; Lian, N; Liu, L; Shi, L | 1 |
| Aiempanakit, K | 1 |
| D, S; Dogra, S; Rajagopalan, M | 1 |
| Callis Duffin, K; Gladman, DD; Goel, N; Gottlieb, AB | 1 |
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| Chandrashekar, L; Priyadarssini, M; Rajappa, M | 1 |
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| Feldman, SR; Margolis, DJ; Nijsten, T; Rolstad, T; Stern, RS | 1 |
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283 review(s) available for methotrexate and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Methotrexate Hepatotoxicity Monitoring Guidelines in Psoriasis and Rheumatoid Arthritis: Is There a Consensus?
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Consensus; Diabetes Mellitus, Type 2; Humans; Methotrexate; Psoriasis | 2021 |
Methotrexate related cutaneous adverse drug reactions: a systematic literature review.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Spondylitis, Ankylosing; Young Adult | 2022 |
Clinical Decisions in Pediatric Psoriasis: A Practical Approach to Systemic Therapy.
Topics: Child; Comorbidity; Drug Therapy, Combination; Humans; Methotrexate; Phototherapy; Psoriasis | 2022 |
Time to Relapse After Discontinuing Systemic Treatment for Psoriasis: A Systematic Review.
Topics: Chronic Disease; Cyclosporine; Humans; Interleukin-17; Interleukin-23; Methotrexate; Psoriasis; Recurrence; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2022 |
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.
Topics: Adalimumab; Adult; Biological Products; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Network Meta-Analysis; Psoriasis; Systematic Reviews as Topic; Tumor Necrosis Factor-alpha; Ustekinumab | 2022 |
Efficacy of adalimumab in pediatric generalized pustular psoriasis: case series and literature review.
Topics: Acitretin; Acute Disease; Adalimumab; Adult; Child; Chronic Disease; Humans; Methotrexate; Psoriasis; Skin Diseases, Vesiculobullous | 2022 |
Management of Coexisting Bullous Pemphigoid and Psoriasis: A Review.
Topics: Acitretin; Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Biological Factors; Biological Products; Cyclosporins; Dermatologic Agents; Etanercept; Humans; Immunosuppressive Agents; Methotrexate; Niacinamide; Pemphigoid, Bullous; Psoriasis; Rituximab; Ustekinumab; Vitamins | 2022 |
Association Between Low-Dose Methotrexate Exposure and Melanoma: A Systematic Review and Meta-analysis.
Topics: Arthritis, Rheumatoid; Humans; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Psoriasis | 2022 |
The cardiometabolic conditions of psoriatic disease.
Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Cytokines; Humans; Inflammation; Interleukin-17; Interleukin-23; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2022 |
Management of Peripheral Arthritis in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Humans; Interleukin-12; Janus Kinase Inhibitors; Methotrexate; Psoriasis | 2023 |
Fatal low-dose methotrexate toxicity: A case report and literature review.
Topics: Aged; Arthritis, Psoriatic; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Male; Methotrexate; Psoriasis; Risk Factors | 2022 |
A meta-analysis of methotrexate polyglutamates in relation to efficacy and toxicity of methotrexate in inflammatory arthritis, colitis and dermatitis.
Topics: Antirheumatic Agents; Arthritis; Colitis; Dermatitis; Dermatologic Agents; Humans; Immunomodulating Agents; Methotrexate; Psoriasis | 2023 |
Nanotechnology-based alternatives for the topical delivery of immunosuppressive agents in psoriasis.
Topics: Drug Carriers; Humans; Immunosuppressive Agents; Methotrexate; Nanoparticles; Nanotechnology; Psoriasis | 2023 |
Liver fibrosis for the dermatologist: a review.
Topics: Dermatologists; Fibrosis; Humans; Liver Cirrhosis; Methotrexate; Non-alcoholic Fatty Liver Disease; Psoriasis | 2023 |
Current management of generalized pustular psoriasis.
Topics: Acute Disease; CARD Signaling Adaptor Proteins; Chronic Disease; Cyclosporine; Female; Guanylate Cyclase; Humans; Interleukins; Membrane Proteins; Methotrexate; Psoriasis; Retinoids; Skin Diseases, Vesiculobullous | 2023 |
Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated Review.
Topics: Acitretin; Endonucleases; Humans; Methotrexate; Pharmacogenetics; Psoriasis; Tumor Necrosis Factor Inhibitors | 2023 |
Genetic Influence on Treatment Response in Psoriasis: New Insights into Personalized Medicine.
Topics: HLA Antigens; HLA-C Antigens; Humans; Methotrexate; Polymorphism, Single Nucleotide; Precision Medicine; Psoriasis; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2023 |
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.
Topics: Adult; Biological Products; Female; Humans; Infliximab; Male; Methotrexate; Network Meta-Analysis; Psoriasis; Systematic Reviews as Topic; Tumor Necrosis Factor-alpha; Ustekinumab | 2023 |
How does methotrexate work?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Cell Line; Crohn Disease; Folic Acid; Humans; Inflammation; Janus Kinases; MAP Kinase Signaling System; Methotrexate; Psoriasis; Signal Transduction; STAT Transcription Factors | 2020 |
Cholestasis and disseminated histoplasmosis in a psoriatic patient on infliximab: case report and review of literature.
Topics: Cholestasis; Female; Histoplasma; Histoplasmosis; Humans; Immunocompromised Host; Infliximab; Methotrexate; Middle Aged; Psoriasis | 2020 |
Topical methotrexate in dermatology: a review of the literature.
Topics: Dermatologic Agents; Dermatology; Humans; Methotrexate; Mycosis Fungoides; Psoriasis; Skin Neoplasms | 2022 |
Tapering and discontinuation of systemic medications in psoriasis patients with low disease activity.
Topics: Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Psoriasis; Quality of Life; Severity of Illness Index | 2020 |
Anti-CD6 mAbs for the treatment of psoriasis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; Cell Differentiation; Cyclosporine; Humans; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2020 |
Efficacy and Safety of Systemic Treatments for Skin and Joint Manifestations in Patients With Psoriasis.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Psoriatic; Cyclosporine; Humans; Methotrexate; Psoriasis | 2020 |
Management of nail psoriasis.
Topics: Administration, Topical; Child; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Nail Diseases; Nails; Psoriasis | 2021 |
Intralesional methotrexate in dermatology: Diverse indications and practical considerations.
Topics: Dermatology; Humans; Injections, Intralesional; Keratoacanthoma; Methotrexate; Psoriasis | 2021 |
Inflammatory nail conditions. Part 1: nail changes in psoriasis.
Topics: Administration, Topical; Dermatologic Agents; Dermoscopy; Glucocorticoids; Humans; Injections, Intralesional; Methotrexate; Nail Diseases; Nails; Psoriasis; Steroids; Triamcinolone | 2021 |
Does methotrexate cause progressive fibrotic interstitial lung disease? A systematic review.
Topics: Causality; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Methotrexate; Psoriasis | 2021 |
PASI 100 response rates in moderate to severe psoriasis: a systematic literature review and analysis of clinical practice guidelines.
Topics: Humans; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2022 |
Are biologics combined with methotrexate better than biologics monotherapy in psoriasis and psoriatic arthritis: A meta-analysis of randomized controlled trials.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Psoriatic; Biological Products; Humans; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Treatment Outcome | 2021 |
Translating the 2020 AAD-NPF Guidelines of Care for the Management of Psoriasis With Systemic Nonbiologics to Clinical Practice.
Topics: Acitretin; Adult; Cyclosporine; Humans; Methotrexate; Psoriasis; United States | 2021 |
Methotrexate and cardiovascular risk in rheumatic diseases:A comprehensive review.
Topics: Animals; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cardiovascular Diseases; Heart Disease Risk Factors; Humans; Inflammation; Methotrexate; Oxidative Stress; Psoriasis | 2021 |
Recent Advancement in Topical Nanocarriers for the Treatment of Psoriasis.
Topics: Administration, Cutaneous; Animals; Cyclosporine; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Liposomes; Methotrexate; Nanocapsules; Psoriasis; Salicylic Acid | 2021 |
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Humans; Methotrexate; Psoriasis | 2021 |
Preclinical study of methotrexate-based hydrogels versus surfactant based liquid crystal systems on psoriasis treatment.
Topics: Animals; Hydrogels; Liquid Crystals; Methotrexate; Mice; Psoriasis; Surface-Active Agents; Swine | 2021 |
Diagnosis and management of psoriasis.
Topics: Administration, Topical; Adrenal Cortex Hormones; Biological Factors; Cholecalciferol; Chronic Disease; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Phototherapy; Psoriasis; Severity of Illness Index | 2017 |
Management of psoriatic arthritis among cutaneous psoriasis patients: from pathogenesis to therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Psoriatic; Cooperative Behavior; Dermatologic Agents; Early Diagnosis; Humans; Methotrexate; Psoriasis; Quality of Life; Risk Factors | 2017 |
Methotrexate in the Treatment of Psoriasis and Rheumatoid Arthritis: Mechanistic Insights, Current Issues and Novel Delivery Approaches.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Delivery Systems; Humans; Methotrexate; Psoriasis | 2017 |
Psoriasis and Cardiovascular Comorbidities: Focusing on Severe Vascular Events, Cardiovascular Risk Factors and Implications for Treatment.
Topics: Cardiovascular Diseases; Comorbidity; Female; Humans; Male; Methotrexate; Psoriasis; Risk Factors | 2017 |
Immunosuppression/Infections across Indications.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Candidiasis; Clinical Trials as Topic; Cyclosporine; Cytokines; Etanercept; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infliximab; Methotrexate; Psoriasis; Surgical Wound Infection; Tuberculosis; Ustekinumab; Virus Diseases | 2018 |
Liver Illness and Psoriatic Patients.
Topics: Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Cyclosporine; Humans; Inflammation; Liver; Liver Diseases; Methotrexate; Psoriasis | 2018 |
Persistence and effectiveness of nonbiologic systemic therapies for moderate-to-severe psoriasis in adults: a systematic review.
Topics: Acitretin; Adult; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Fumarates; Humans; Methotrexate; Multicenter Studies as Topic; Observational Studies as Topic; Psoriasis; Severity of Illness Index; Treatment Outcome | 2019 |
Secukinumab (Cosentyx°) and plaque psoriasis.
Topics: Acitretin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Cyclosporine; Etanercept; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Psoriasis; PUVA Therapy; Severity of Illness Index; Treatment Failure; Tumor Necrosis Factor-alpha; Ultraviolet Therapy | 2017 |
Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus.
Topics: Acitretin; Administration, Oral; Administration, Topical; Adult; Aged; Biological Products; Consensus; Cyclosporine; Dermatologic Agents; Disease Management; Expert Testimony; Female; Humans; Injections, Intralesional; Male; Methotrexate; Middle Aged; Nail Diseases; Practice Guidelines as Topic; Psoriasis; Recurrence; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2019 |
The pharmacological management of patients with comorbid psoriasis and obesity.
Topics: Adipokines; Antibodies, Monoclonal; Cytokines; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Obesity; Phototherapy; Psoriasis | 2019 |
Moderate to severe plaque psoriasis - treatment with drugs of the classic scheme.
Topics: Acitretin; Antibodies, Monoclonal; Brazil; Clinical Decision-Making; Cyclosporine; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Severity of Illness Index; Time Factors; Treatment Outcome | 2019 |
Osteoporosis and Psoriasis.
Topics: Adrenal Cortex Hormones; Bone and Bones; Bone Density; Densitometry; Female; Fractures, Spontaneous; Humans; Immunosuppressive Agents; Male; Methotrexate; Osteoporosis; Psoriasis; Risk Factors; Vitamin D | 2019 |
Interventions for nail psoriasis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Humans; Infliximab; Methotrexate; Nail Diseases; Psoriasis; Quality of Life; Randomized Controlled Trials as Topic; Ustekinumab | 2013 |
The effect of folate supplementation on methotrexate efficacy and toxicity in psoriasis patients and folic acid use by dermatologists in the USA.
Topics: Dermatology; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Methotrexate; Psoriasis; United States | 2013 |
Sarcoidosis and psoriasis: a case series and review of the literature exploring co-incidence vs coincidence.
Topics: Adult; Aged; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Peptidyl-Dipeptidase A; Psoriasis; Radiography; Sarcoidosis, Pulmonary; Steroids; Th1 Cells; Th17 Cells | 2013 |
Systemic methotrexate therapy for psoriasis: past, present and future.
Topics: Dermatologic Agents; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2013 |
An update on drug-drug interactions with biologics for the treatment of moderate-to-severe psoriasis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Cyclosporine; Cytochrome P-450 Enzyme System; Drug Interactions; Etanercept; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; United States; Ustekinumab | 2014 |
Infliximab in psoriasis and psoriatic arthritis.
Topics: Adult; Antibodies, Monoclonal; Arthritis, Psoriatic; Clinical Trials as Topic; Dermatologic Agents; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Molecular Targeted Therapy; Nails; Psoriasis; Quality of Life; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
Treatment of psoriasis and psoriatic arthritis.
Topics: Adalimumab; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Dermatologic Agents; Humans; Infliximab; Interleukin-12; Interleukin-23; Methotrexate; Molecular Targeted Therapy; Psoriasis; Recombinant Fusion Proteins; Ustekinumab | 2013 |
From the Medical Board of the National Psoriasis Foundation: Vaccination in adult patients on systemic therapy for psoriasis.
Topics: Contraindications; Humans; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Psoriasis; Risk Factors; Travel; Tumor Necrosis Factor-alpha; Vaccination | 2013 |
Antidrug antibodies in psoriasis: a systematic review.
Topics: Adalimumab; Antibodies; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Factors; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Immunologic Factors; Immunosuppressive Agents; Infliximab; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Ustekinumab | 2014 |
Anti-drug antibodies in psoriasis: a critical evaluation of clinical significance and impact on treatment response.
Topics: Adalimumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Formation; Etanercept; Humans; Immunoglobulin G; Immunomodulation; Infliximab; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Treatment Outcome; Ustekinumab | 2013 |
Efficacy and safety of systemic treatments for moderate-to-severe psoriasis: meta-analysis of randomized controlled trials.
Topics: Biological Factors; Cyclosporine; Dermatologic Agents; Fumarates; Humans; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Retinoids; Risk Factors; Treatment Outcome | 2014 |
From the Medical Board of the National Psoriasis Foundation: The risk of cardiovascular disease in individuals with psoriasis and the potential impact of current therapies.
Topics: Acitretin; Antibodies, Monoclonal, Humanized; Biological Therapy; Cardiovascular Diseases; Cyclosporine; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Mycophenolic Acid; Psoriasis; PUVA Therapy; Tumor Necrosis Factor-alpha; Ustekinumab | 2014 |
Psoriasis.
Topics: Acitretin; Administration, Topical; Cardiovascular Diseases; Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Phototherapy; Psoriasis; Tumor Necrosis Factor-alpha | 2013 |
Does treatment of psoriasis reduce the risk of cardiovascular disease?
Topics: Biomarkers; Cardiovascular Diseases; Humans; Inflammation; Inflammation Mediators; Interleukin-12; Interleukin-23; Methotrexate; Phototherapy; Psoriasis; Risk Factors; Tumor Necrosis Factor-alpha | 2014 |
Ustekinumab : targeting the IL-17 pathway to improve outcomes in psoriatic arthritis.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Psoriatic; Drug Approval; Humans; Interleukin-17; Methotrexate; Psoriasis; Signal Transduction; Treatment Outcome; Tumor Necrosis Factor-alpha; Ustekinumab | 2014 |
Diagnostic accuracy of noninvasive markers of liver fibrosis in patients with psoriasis taking methotrexate: a systematic review and meta-analysis.
Topics: Biomarkers; Dermatologic Agents; Diagnostic Imaging; Epidemiologic Methods; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Quality Assurance, Health Care; Reference Standards | 2014 |
Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies.
Topics: Comorbidity; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Observational Studies as Topic; Prognosis; Psoriasis; Publication Bias; Selection Bias | 2014 |
In brief: otrexup--a single-use auto-injector formulation of methotrexate.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Chemistry, Pharmaceutical; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Self Administration | 2014 |
Psoriasis: to treat or to manage?
Topics: Antibodies, Anti-Idiotypic; Biological Products; Comorbidity; Humans; Immunosuppressive Agents; Methotrexate; Obesity; Psoriasis; Risk Factors; Treatment Outcome | 2014 |
Folate supplementation reduces the side effects of methotrexate therapy for psoriasis.
Topics: Antirheumatic Agents; Dose-Response Relationship, Drug; Folic Acid; Humans; Leucovorin; Methotrexate; Psoriasis; Severity of Illness Index; Vitamin B Complex | 2014 |
Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Certolizumab Pegol; Drug Therapy, Combination; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Polyethylene Glycols; Psoriasis; Randomized Controlled Trials as Topic; Recurrence; Rheumatic Diseases; Risk Factors; Tuberculosis; Tumor Necrosis Factor-alpha | 2014 |
Combined use of systemic agents for psoriasis: a systematic review.
Topics: Dermatologic Agents; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor | 2014 |
The role of TNF inhibitors in psoriatic disease.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Comorbidity; Humans; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2014 |
Network Meta-analysis of Treatments for Chronic Plaque Psoriasis in Canada.
Topics: Adalimumab; Alefacept; Canada; Clinical Trials, Phase III as Topic; Dermatologic Agents; Etanercept; Humans; Infliximab; Methotrexate; Network Meta-Analysis; Psoriasis; Recombinant Fusion Proteins; Severity of Illness Index; Ustekinumab | 2014 |
Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities.
Topics: Acitretin; Adipokines; Alcoholism; Antibodies, Monoclonal, Humanized; Cardiovascular Diseases; Comorbidity; Cyclosporine; Dermatologic Agents; Diabetes Mellitus; Fumarates; Humans; Immunosuppressive Agents; Inflammation; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; Risk Factors; Smoking; Tumor Necrosis Factor-alpha; Ustekinumab | 2015 |
Current and future oral systemic therapies for psoriasis.
Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Cyclosporine; Fumarates; Humans; Hydroxyurea; Immunosuppressive Agents; Isoxazoles; Keratolytic Agents; Leflunomide; Methotrexate; Mycophenolic Acid; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Sulfasalazine; Thalidomide; Thioguanine | 2015 |
Pharmacogenomics and the resulting impact on psoriasis therapies.
Topics: Acitretin; Cyclosporine; Cytokines; HLA-C Antigens; Humans; Immunosuppressive Agents; Inflammation; Keratolytic Agents; Methotrexate; Pharmacogenetics; Phototherapy; Polymorphism, Genetic; Precision Medicine; Psoriasis; Research Design; Tumor Necrosis Factor-alpha | 2015 |
Combining biologics with methotrexate in psoriasis: a systematic review.
Topics: Biological Products; Dermatologic Agents; Drug Therapy, Combination; Humans; Methotrexate; Prospective Studies; Psoriasis; Retrospective Studies | 2015 |
Etanercept combined with systemic drugs or phototherapy for treatment of psoriasis.
Topics: Acitretin; Antirheumatic Agents; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Etanercept; Humans; Methotrexate; Multicenter Studies as Topic; Prospective Studies; Psoriasis; Treatment Outcome; Ultraviolet Therapy | 2015 |
The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cardiovascular Diseases; Humans; Methotrexate; Psoriasis; Risk Factors; Tumor Necrosis Factor-alpha | 2015 |
Methotrexate Dosing Regimen for Plaque-type Psoriasis: A Systematic Review of the Use of Test-dose, Start-dose, Dosing Scheme, Dose Adjustments, Maximum Dose and Folic Acid Supplementation.
Topics: Dietary Supplements; Drug Administration Schedule; Drug Dosage Calculations; Drug Therapy, Combination; Folic Acid; Humans; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Psoriasis; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Methotrexate use and risk of lung disease in psoriasis, psoriatic arthritis, and inflammatory bowel disease: systematic literature review and meta-analysis of randomised controlled trials.
Topics: Adult; Arthritis, Psoriatic; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lung Diseases; Methotrexate; Psoriasis; Risk Factors | 2015 |
Systemic methotrexate for the treatment of psoriasis.
Topics: Animals; Biological Availability; Clinical Trials as Topic; Dermatologic Agents; Humans; Methotrexate; Multidrug Resistance-Associated Proteins; Psoriasis | 2015 |
Immunogenicity of biologic treatments for psoriasis: therapeutic consequences and the potential value of concomitant methotrexate.
Topics: Animals; Antibodies; Biological Factors; Dermatologic Agents; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2015 |
Magnetic resonance elastography and transient elastography as non-invasive analyses for liver fibrosis: can they obviate the need for liver biopsy in psoriasis patients treated with methotrexate?
Topics: Biopsy; Dermatologic Agents; Elasticity Imaging Techniques; Humans; Liver; Liver Cirrhosis; Magnetic Resonance Imaging; Methotrexate; Psoriasis | 2015 |
Treating Psoriasis During Pregnancy: Safety and Efficacy of Treatments.
Topics: Acitretin; Administration, Cutaneous; Adrenal Cortex Hormones; Calcineurin Inhibitors; Calcitriol; Coal Tar; Contraindications; Cyclosporine; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Methotrexate; Nicotinic Acids; Pregnancy; Pregnancy Complications; Psoriasis; PUVA Therapy; Tumor Necrosis Factor-alpha; Ultraviolet Therapy; Ustekinumab | 2015 |
Paradoxical psoriatic arthritis in a patient with psoriasis treated with ustekinumab.
Topics: Arthritis, Psoriatic; Dermatologic Agents; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Psoriasis; Treatment Outcome; Ustekinumab; Withholding Treatment | 2015 |
Oral fumaric acid esters for psoriasis.
Topics: Administration, Oral; Arthritis, Psoriatic; Dermatologic Agents; Fumarates; Humans; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Severity of Illness Index | 2015 |
Systemic Treatment of Recalcitrant Pediatric Psoriasis: A Case Series and Literature Review.
Topics: Adalimumab; Adolescent; Child; Child, Preschool; Cyclosporine; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Ultraviolet Therapy; Ustekinumab | 2015 |
Protective effects of methotrexate against ischemic cardiovascular disorders in patients treated for rheumatoid arthritis or psoriasis: novel therapeutic insights coming from a meta-analysis of the literature data.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Humans; Methotrexate; Psoriasis | 2016 |
Methotrexate in Moderate to Severe Psoriasis: Review of the Literature and Expert Recommendations.
Topics: Contraindications; Hepatitis B, Chronic; HIV Infections; Humans; Methotrexate; Neoplasms; Practice Guidelines as Topic; Psoriasis; Risk Factors | 2016 |
Managing Patients With Psoriasis in the Busy Clinic: Practical Tips for Health Care Practitioners.
Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Cyclosporine; Disease Progression; Humans; Immunosuppressive Agents; Insurance, Health, Reimbursement; Keratolytic Agents; Medication Adherence; Methotrexate; Psoriasis; Symptom Flare Up; Thalidomide | 2016 |
Methotrexate: practical use in dermatology.
Topics: Anti-Inflammatory Agents; Dermatologic Agents; Dermatology; Humans; Methotrexate; Psoriasis; Skin Diseases | 2016 |
Ultraviolet B Phototherapy for Psoriasis: Review of Practical Guidelines.
Topics: Acitretin; Administration, Topical; Combined Modality Therapy; Contraindications; Dermatologic Agents; Dose-Response Relationship, Radiation; Humans; Interleukin-17; Keratolytic Agents; Lasers, Excimer; Low-Level Light Therapy; Methotrexate; Phosphodiesterase Inhibitors; Practice Guidelines as Topic; Psoriasis; PUVA Therapy; Skin; Tumor Necrosis Factor-alpha; Ultraviolet Therapy | 2016 |
Risk of Serious Infections in Patients with Psoriasis on Biologic Therapies: A Systematic Review and Meta-Analysis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Biological Therapy; Humans; Infections; Methotrexate; Odds Ratio; Phototherapy; Proportional Hazards Models; Psoriasis; Randomized Controlled Trials as Topic; Retinoids; Risk Factors; Time Factors; Ustekinumab | 2016 |
Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments.
Topics: Administration, Oral; Dermatologic Agents; Fumarates; Humans; Methotrexate; Placebos; Psoriasis; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Safety and Efficacy of Methotrexate in Psoriasis: A Meta-Analysis of Published Trials.
Topics: Arthritis, Rheumatoid; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Nausea; Opportunistic Infections; Oral Ulcer; Patient Safety; Psoriasis; Risk; Treatment Outcome | 2016 |
The Effect of TNF Inhibitors on Cardiovascular Events in Psoriasis and Psoriatic Arthritis: an Updated Meta-Analysis.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Psoriatic; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Incidence; Methotrexate; Odds Ratio; Patient Outcome Assessment; Psoriasis; Tumor Necrosis Factor Inhibitors | 2016 |
The Australasian Psoriasis Collaboration view on methotrexate for psoriasis in the Australasian setting.
Topics: Alcohol Drinking; Australia; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Drug Monitoring; Drug Therapy, Combination; Humans; Liver Diseases; Methotrexate; New Zealand; Psoriasis; Reproductive Health | 2017 |
Comparative efficacy and incremental cost per responder of methotrexate versus apremilast for methotrexate-naïve patients with psoriasis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Drug Costs; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Thalidomide; Treatment Outcome | 2016 |
Methotrexate and lung disease in rheumatoid arthritis.
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Female; Humans; Incidence; Inflammatory Bowel Diseases; Lung Diseases; Lung Diseases, Interstitial; Male; Methotrexate; Prevalence; Psoriasis | 2017 |
New targets in psoriatic arthritis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Psoriatic; Cyclophosphamide; Etanercept; Humans; Infliximab; Methotrexate; Molecular Targeted Therapy; Phosphodiesterase 4 Inhibitors; Piperidines; Psoriasis; Pyrimidines; Pyrroles; Sulfasalazine; Thalidomide; Ustekinumab | 2016 |
Advances in Psoriasis.
Topics: Acitretin; Administration, Topical; Adrenal Cortex Hormones; Cyclosporine; Dermatologic Agents; Humans; Interleukins; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Tumor Necrosis Factor-alpha; Vitamin D | 2017 |
Relative risk of and determinants for adverse events of methotrexate prescribed at a low dose: a systematic review and meta-analysis of randomized placebo-controlled trials.
Topics: Anti-Asthmatic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Asthma; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Randomized Controlled Trials as Topic; Risk Factors | 2017 |
New insights and therapies for teenage psoriasis.
Topics: Administration, Cutaneous; Adolescent; Anti-Bacterial Agents; Calcineurin; Calcineurin Inhibitors; Causality; Comorbidity; Dermatologic Agents; Etanercept; Glucocorticoids; HLA-C Antigens; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukin-12; Interleukin-23; Methotrexate; Phototherapy; Psoriasis; Receptors, Tumor Necrosis Factor; Retinoids; Vitamin D; Vitamins | 2008 |
Methotrexate for psoriasis in the era of biological therapy.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Therapy; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 2008 |
Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Eruptions; Folic Acid; Gastrointestinal Diseases; Hematologic Diseases; Humans; Immunosuppressive Agents; Leucovorin; Liver Diseases; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic | 2009 |
EBV-associated diffuse large B-cell lymphoma in a psoriatic treated with methotrexate.
Topics: Dermatologic Agents; Disease Progression; Epstein-Barr Virus Infections; Fatal Outcome; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Polymerase Chain Reaction; Psoriasis; Severity of Illness Index | 2009 |
Treatments for psoriasis and the risk of malignancy.
Topics: Biological Products; Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Mycophenolic Acid; Psoriasis; PUVA Therapy; Skin Neoplasms; Ultraviolet Therapy | 2009 |
Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis; Renal Dialysis; Renal Insufficiency | 2009 |
Retinoids, methotrexate and cyclosporine.
Topics: Cyclosporine; Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis; Retinoids | 2009 |
Efficacy and safety of treatments for childhood psoriasis: a systematic literature review.
Topics: Anthralin; Anti-Bacterial Agents; Calcineurin Inhibitors; Calcitriol; Child; Dermatologic Agents; Glucocorticoids; Humans; Methotrexate; Psoriasis | 2010 |
Treatment of moderate-to-severe plaque psoriasis.
Topics: Abnormalities, Drug-Induced; Alefacept; Antibodies, Monoclonal; Clinical Trials as Topic; Contraindications; Cyclosporine; Etanercept; Female; Fumarates; Hematologic Diseases; Humans; Hypertension; Immunoglobulin G; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Photochemotherapy; Pregnancy; Pregnancy Complications; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retinoids; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2009 |
Comorbidities in patients with psoriasis.
Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Dermatologic Agents; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methotrexate; Neoplasms; Obesity; Psoriasis | 2009 |
Treatment of acrodermatitis continua of Hallopeau with TNF-blocking agents: case report and review.
Topics: Acitretin; Acrodermatitis; Adalimumab; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Betamethasone; Clobetasol; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Mycophenolic Acid; Nails; Paronychia; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor Inhibitors | 2010 |
Combining etanercept with traditional agents in the treatment of psoriasis: a review of the clinical evidence.
Topics: Cyclosporine; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Phototherapy; Psoriasis; Receptors, Tumor Necrosis Factor | 2010 |
New-onset psoriasis associated with etanercept therapy.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Humans; Immunoglobulin G; Isoxazoles; Leflunomide; Male; Methotrexate; Prednisolone; Psoriasis; Receptors, Tumor Necrosis Factor; Spondylitis, Ankylosing; Sulfasalazine; Tumor Necrosis Factor-alpha | 2010 |
[Prescription and surveillance of treatment by a systemic agent or biotherapy in psoriasis].
Topics: Biological Products; Contraindications; Cyclosporine; Drug Administration Routes; Drug Monitoring; Female; Folic Acid; Humans; Immunosuppressive Agents; Kidney Diseases; Latent Tuberculosis; Liver Cirrhosis; Medical History Taking; Methotrexate; Pregnancy; Pregnancy Complications; Psoriasis; Pulmonary Fibrosis; Recurrence; Tumor Necrosis Factor-alpha; Vaccination | 2010 |
[What is the impact of the new clinical trial data? What are the lessons for patient management?].
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Therapy; Clinical Trials as Topic; Dermatologic Agents; Disease Management; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Methotrexate; Multicenter Studies as Topic; Psoriasis; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Therapies, Investigational; Treatment Outcome; Ustekinumab | 2010 |
Systemic combination treatment for psoriasis: a review.
Topics: Biological Products; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Methotrexate; Photochemotherapy; Photosensitizing Agents; Psoriasis; Retinoids; Treatment Outcome | 2010 |
A rare case of non-Hodgkins B-cell lymphoma in a psoriatic patient: a case report and literature review.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Female; Humans; Immunosuppressive Agents; Lymphoma, B-Cell; Methotrexate; Middle Aged; Psoriasis | 2010 |
How genetic variation affects patient response and outcome to therapy for psoriasis.
Topics: Biomarkers, Pharmacological; Clinical Trials as Topic; Genetic Association Studies; Genetic Testing; Humans; Methotrexate; Pharmacogenetics; Polymorphism, Genetic; Precision Medicine; Psoriasis; Receptors, Calcitriol; Vitamin D | 2010 |
Pharmacogenetics of psoriasis.
Topics: Acitretin; Adrenal Cortex Hormones; Antibodies, Monoclonal; Cyclosporine; Genetic Predisposition to Disease; Humans; Methotrexate; Pharmacogenetics; Precision Medicine; Psoriasis | 2011 |
Assessment and management of methotrexate hepatotoxicity in psoriasis patients: report from a consensus conference to evaluate current practice and identify key questions toward optimizing methotrexate use in the clinic.
Topics: Biomarkers; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Dietary Supplements; Folic Acid; Humans; Liver; Methotrexate; Pharmacogenetics; Psoriasis; Risk Factors | 2011 |
Metabolic comorbidities and psoriasis.
Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Dyslipidemias; Fatty Liver; Humans; Hypertriglyceridemia; Immunosuppressive Agents; Insulin Resistance; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Psoriasis; Risk Factors | 2010 |
Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity.
Topics: Chemical and Drug Induced Liver Injury; Dermatologic Agents; Humans; Incidence; Methotrexate; Psoriasis; Risk Factors; Treatment Outcome | 2011 |
Evidence-based recommendations on conventional systemic treatments in psoriasis: systematic review and expert opinion of a panel of dermatologists.
Topics: Cyclosporine; Dermatology; Evidence-Based Practice; Humans; Methotrexate; Psoriasis; Retinoids; Treatment Outcome | 2011 |
A review of phototherapy protocols for psoriasis treatment.
Topics: Acitretin; Carotid Stenosis; Clinical Protocols; Humans; Immunosuppressive Agents; Keratolytic Agents; Lasers, Excimer; Methotrexate; Psoriasis; PUVA Therapy; Treatment Outcome; Ultraviolet Therapy | 2011 |
Psoriasis in the elderly: from the Medical Board of the National Psoriasis Foundation.
Topics: Aged; Alefacept; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Ultraviolet Therapy | 2011 |
Systemic therapy of psoriasis: methotrexate.
Topics: Anti-Inflammatory Agents; Arthritis, Psoriatic; Folic Acid Antagonists; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2011 |
Systematic review and meta-analysis of methotrexate use and risk of cardiovascular disease.
Topics: Antirheumatic Agents; Arthritis; Cardiovascular Diseases; Humans; Inflammation; Methotrexate; Psoriasis; Risk Assessment | 2011 |
Genetic susceptibility to psoriasis and psoriatic arthritis: implications for therapy.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Biological Products; Dermatologic Agents; Forecasting; Genetic Markers; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Methotrexate; Pharmacogenetics; Polymorphism, Genetic; Psoriasis | 2012 |
Effective and sustainable biologic treatment of psoriasis: what can we learn from new clinical data?
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Methotrexate; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Tumor Necrosis Factor-alpha; Ustekinumab | 2012 |
[Nail psoriasis--an ignored disorder. Pathogenesis, diagnosis and therapy].
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Biological Products; Cross-Sectional Studies; Drug Administration Schedule; Evidence-Based Medicine; Glucocorticoids; Humans; Methotrexate; Onycholysis; Psoriasis | 2012 |
Psoriasis and cardiovascular disorders.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Cardiotonic Agents; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Humans; Inflammation; Interleukin-12 Subunit p40; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Smoking; Tumor Necrosis Factor-alpha; Ustekinumab | 2012 |
A retrospective review of methotrexate-induced hepatotoxicity among patients with psoriasis in a tertiary dermatology center in Malaysia.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Liver; Malaysia; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index; Tertiary Care Centers; Time Factors; Young Adult | 2013 |
Comparative tolerability of systemic treatments for plaque-type psoriasis.
Topics: Acitretin; Cyclosporine; Dermatologic Agents; Drug Combinations; Eye Diseases; Humans; Keratolytic Agents; Liver Cirrhosis; Lymphoproliferative Disorders; Methotrexate; Nausea; Pancytopenia; Pneumonia; Pruritus; Psoriasis; PUVA Therapy; Skin Neoplasms | 2002 |
Vitamin D and systemic therapy.
Topics: Acitretin; Administration, Oral; Administration, Topical; Calcitriol; Clinical Trials as Topic; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Keratolytic Agents; Methotrexate; Ointments; Psoriasis | 2002 |
A molecule solves psoriasis? Systemic therapies for psoriasis inducing interleukin 4 and Th2 responses.
Topics: Cholecalciferol; Cyclosporine; Cytokines; Fumarates; Humans; Inflammation Mediators; Interleukin-4; Methotrexate; Phototherapy; Psoriasis; Th1 Cells; Th2 Cells; Vitamin A | 2003 |
Current systemic therapies for psoriasis: where are we now?
Topics: Acitretin; Antineoplastic Agents; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Remission Induction | 2003 |
Combining the new biologic agents with our current psoriasis armamentarium.
Topics: Alefacept; Antibodies, Monoclonal; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Infliximab; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Recombinant Fusion Proteins | 2003 |
Transition from methotrexate and cyclosporine to other therapies including retinoids, ultraviolet light and biologic agents in the management of patients with psoriasis.
Topics: Acitretin; Cyclosporine; Drug Therapy, Combination; Etretinate; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Phototherapy; Psoriasis; Recombinant Fusion Proteins; Treatment Outcome | 2003 |
Methotrexate and psoriasis in the era of new biologic agents.
Topics: Arthritis, Rheumatoid; Combined Modality Therapy; Dermatologic Agents; Humans; Methotrexate; Practice Guidelines as Topic; Psoriasis | 2004 |
Combination therapy to treat moderate to severe psoriasis.
Topics: Acitretin; Calcitriol; Drug Therapy, Combination; Humans; Methotrexate; Psoriasis; PUVA Therapy | 2004 |
[Methotrexate therapy in psoriasis].
Topics: Dermatologic Agents; Drug Costs; Humans; Liver; Methotrexate; Patient Selection; Psoriasis | 2004 |
[Psoriasis].
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Combined Modality Therapy; Cyclosporins; Diagnosis, Differential; Humans; Infliximab; Major Histocompatibility Complex; Methotrexate; Peritoneal Dialysis; Prognosis; Psoriasis; PUVA Therapy; Renal Dialysis; Th1 Cells | 2004 |
Biologics in combination with nonbiologics: efficacy and safety.
Topics: Antibodies, Monoclonal; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2004 |
[The practice guideline 'Photo(chemo)therapy and systemic therapy in severe chronic plaque-psoriasis'].
Topics: Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Photochemotherapy; Practice Guidelines as Topic; Psoriasis; Safety; Treatment Outcome; Ultraviolet Therapy | 2004 |
Methotrexate reduces incidence of vascular diseases in veterans with psoriasis or rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cohort Studies; Comorbidity; Databases, Factual; Drug Synergism; Drug Therapy, Combination; Female; Florida; Folic Acid; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Incidence; Male; Medical Records Systems, Computerized; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk; Vascular Diseases; Veterans | 2005 |
Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks.
Topics: Administration, Oral; Chronic Disease; Cyclosporine; Dermatologic Agents; Ficusin; Fumarates; Humans; Immunosuppressive Agents; Methotrexate; Photosensitizing Agents; Psoriasis; PUVA Therapy; Retinoids; Risk Assessment; Ultraviolet Therapy | 2005 |
Combining traditional agents and biologics for the treatment of psoriasis.
Topics: Acitretin; Adalimumab; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Clinical Trials as Topic; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Infliximab; Methotrexate; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins | 2005 |
Chronic plaque psoriasis.
Topics: Anthralin; Anti-Inflammatory Agents; Combined Modality Therapy; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; PUVA Therapy; Retinoids; Ultraviolet Therapy; Vitamin D | 2005 |
Folate supplementation during methotrexate therapy for patients with psoriasis.
Topics: Drug Therapy, Combination; Folic Acid; Gastrointestinal Tract; Hematinics; Humans; Immunosuppressive Agents; Leucovorin; Methotrexate; Psoriasis | 2005 |
The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis.
Topics: Folic Acid; Humans; Immunosuppressive Agents; Methotrexate; Pharmacogenetics; Polymorphism, Genetic; Psoriasis | 2005 |
Optimal management of severe plaque form of psoriasis.
Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Combined Modality Therapy; Dermatologic Agents; Female; Follow-Up Studies; Humans; Male; Methotrexate; Patient Satisfaction; Photochemotherapy; Psoriasis; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Gynaecomastia with oligospermia: an unusual complication of low-dose methotrexate for pustular psoriasis.
Topics: Dermatologic Agents; Gynecomastia; Hormones; Humans; Male; Methotrexate; Middle Aged; Oligospermia; Psoriasis | 2006 |
Monitoring liver function during methotrexate therapy for psoriasis: are routine biopsies really necessary?
Topics: Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Liver; Liver Cirrhosis; Methotrexate; Practice Guidelines as Topic; Psoriasis; Risk Factors | 2005 |
[Liver damage in methotrexate-treated patients. When liver biopsy is necessary in the follow-up?].
Topics: Arthritis, Rheumatoid; Biopsy, Needle; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Humans; Immunohistochemistry; Inflammatory Bowel Diseases; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Psoriasis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index | 2005 |
A European perspective on the challenges of managing psoriasis.
Topics: Arthritis, Rheumatoid; Chronic Disease; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Stress, Psychological | 2006 |
The treatment of psoriasis and psoriatic arthritis: an interdisciplinary approach.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cyclosporine; Disease Progression; Etanercept; Etretinate; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Keratolytic Agents; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2006 |
Conventional systemic agents for psoriasis. A systematic review.
Topics: Acitretin; Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Practice Guidelines as Topic; Psoriasis; Thioguanine; Treatment Outcome | 2006 |
[The significance of diet and associated factors in psoriasis].
Topics: Adolescent; Adult; Alcohol Drinking; Antioxidants; Biomarkers; Case-Control Studies; Child; Controlled Clinical Trials as Topic; Dermatologic Agents; Diet, Vegetarian; Energy Intake; Fasting; Fatty Acids, Omega-3; Female; Fish Oils; Food-Drug Interactions; Glutens; Homocysteine; Humans; Male; Methotrexate; Nutritional Status; Psoriasis; Sex Factors; Vitamin D | 2006 |
Cytotoxic and immunologic effects of methotrexate in psoriasis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; DNA; Epidermal Cells; Epidermis; Graft vs Host Disease; Humans; Immune System; Methotrexate; Mice; Psoriasis | 1990 |
Treating itch in psoriasis.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Capsaicin; Coal Tar; Emollients; Histamine H1 Antagonists; Humans; Immunologic Factors; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Mianserin; Mirtazapine; Morpholines; Phototherapy; Pruritus; Psoriasis; Quality of Life; Salicylates; Skin Care; Vitamin D | 2006 |
Chronic plaque psoriasis.
Topics: Adrenal Cortex Hormones; Alefacept; Anthralin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Combined Modality Therapy; Cyclosporine; Cytokines; Dermatologic Agents; Humans; Methotrexate; Nicotinic Acids; Psoriasis; PUVA Therapy; Recombinant Fusion Proteins; Retinoids; Ultraviolet Therapy; Vitamin D | 2006 |
[Biologics in the treatment of psoriasis].
Topics: Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Child; Child, Preschool; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Male; Methotrexate; Pregnancy; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Time Factors | 2006 |
Differential clinical response to alefacept in combination with methotrexate in two patients with refractory palmar psoriasis.
Topics: Alefacept; Drug Therapy, Combination; Female; Hand Dermatoses; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Recombinant Fusion Proteins | 2007 |
Treatment of childhood psoriasis.
Topics: Adrenal Cortex Hormones; Anthralin; Calcitriol; Child; Cyclosporine; Humans; Methotrexate; Nicotinic Acids; Phototherapy; Psoriasis; Retinoids | 2006 |
An attempt to formulate an evidence-based strategy in the management of moderate-to-severe psoriasis: a review of the efficacy and safety of biologics and prebiologic options.
Topics: Acitretin; Adalimumab; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Biological Therapy; Dermatologic Agents; Evidence-Based Medicine; Humans; Methotrexate; Psoriasis; PUVA Therapy; Randomized Controlled Trials as Topic; Recombinant Fusion Proteins | 2007 |
[The immunology of psoriasis: from basic research to the bedside].
Topics: Acitretin; Adrenal Cortex Hormones; Alefacept; Anthralin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Autoimmunity; Biomedical Research; Cell Differentiation; Cell Proliferation; Cyclosporine; Dermatologic Agents; Humans; Immunity, Cellular; Immunosuppressive Agents; Infliximab; Keratinocytes; Keratolytic Agents; Methotrexate; Psoriasis; Recombinant Fusion Proteins; T-Lymphocytes, Regulatory; Ultraviolet Therapy | 2006 |
[Psoriasis].
Topics: Acitretin; Adrenal Cortex Hormones; Adult; Age Factors; Arthritis, Psoriatic; Calcitriol; Child; Cyclosporine; Dermatologic Agents; Diagnosis, Differential; HIV Infections; Humans; Infant; Infant, Newborn; Keratolytic Agents; Methotrexate; Ointments; Phototherapy; Psoriasis; Skin; Time Factors; Vitamins | 2006 |
[Long-term control of psoriasis is necessary].
Topics: Acitretin; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Combined Modality Therapy; Comorbidity; Cyclosporine; Cytokines; Dermatologic Agents; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Quality of Life; Recurrence | 2008 |
Psoriasis therapy: a current perspective.
Topics: Coal Tar; Evaluation Studies as Topic; Glucocorticoids; Humans; Methotrexate; Petrolatum; Psoriasis; PUVA Therapy; Retinoids; Ultraviolet Therapy | 1983 |
Reappraisal of the use of methotrexate in rheumatic disease.
Topics: Absorption; Bone Marrow; Clinical Trials as Topic; Drug Interactions; Humans; Liver; Methotrexate; Myositis; Psoriasis; Rheumatic Diseases; Tissue Distribution | 1983 |
Psoriasis. A review of recent advances in treatment.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Coal Tar; Glucocorticoids; Humans; Hydroxyurea; Hyperthermia, Induced; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Renal Dialysis; Retinoids | 1984 |
Psoriasis and its treatment.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Humans; Hydroxyurea; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Razoxane | 1981 |
Methotrexate therapy of psoriasis. Effect and side effects with particular reference to hepatic changes. A survey.
Topics: Bone Marrow; Chemical and Drug Induced Liver Injury; Chemistry; Drug Evaluation; History, 20th Century; Humans; Liver; Methotrexate; Microscopy, Electron; Psoriasis | 1980 |
International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC publication no. 6: do treatments available for psoriasis patients carry a genetic or carcinogenic risk?
Topics: Anthralin; Azathioprine; Carcinogens; Coal Tar; Humans; Hydroxyurea; Methotrexate; Mutagenicity Tests; Mutagens; Mutation; Probability; Psoriasis; PUVA Therapy; Risk; Salmonella typhimurium | 1981 |
Methotrexate guidelines--revised.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Follow-Up Studies; Humans; Liver; Methotrexate; Psoriasis | 1982 |
Psoriasis in children: characteristics, prognosis and therapy. A review.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Prognosis; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1981 |
Dihydrofolate reductase inhibitors as potential drugs.
Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi | 1981 |
Therapeutic progress. II: Treatment of psoriasis.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Calcitriol; Coal Tar; Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Emollients; Humans; Immunosuppressive Agents; Methotrexate; Phototherapy; Psoriasis; Retinoids; Tacrolimus; United Kingdom | 1994 |
[Methotrexate therapy of inflammatory diseases. Reliable effects and recent developments in rheumatology, pneumology, gastroenterology and dermatology].
Topics: Asthma; Clinical Trials as Topic; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Rheumatic Diseases | 1995 |
Infections during low-dose methotrexate treatment in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Double-Blind Method; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Opportunistic Infections; Prospective Studies; Psoriasis | 1995 |
Pharmacokinetics of etretinate and acitretin with special reference to treatment of psoriasis.
Topics: Absorption; Acitretin; Etretinate; Humans; Methotrexate; Psoriasis; Vitamin A | 1994 |
Monitoring patients taking methotrexate for hepatotoxicity. Does the standard of care match published guidelines?
Topics: Alanine Transaminase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Clinical Protocols; Connecticut; Drug Monitoring; Follow-Up Studies; Gastroenterology; Humans; Liver; Liver Diseases; Massachusetts; Methotrexate; Practice Guidelines as Topic; Psoriasis; Referral and Consultation | 1994 |
[The treatment of psoriasis].
Topics: Adrenal Cortex Hormones; Calcitriol; Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Psoriasis; Ultraviolet Therapy | 1993 |
[Methotrexate and psoriasis. Pharmacology and therapeutic management].
Topics: Humans; Methotrexate; Psoriasis | 1994 |
Methotrexate and reproduction in men: case report and recommendations.
Topics: Adult; Arthritis; Chromosome Aberrations; Chromosome Disorders; Genetic Counseling; Humans; Male; Methotrexate; Mutation; Psoriasis; Spermatogenesis | 1993 |
[Treatment of psoriasis].
Topics: Adrenal Cortex Hormones; Anthralin; Combined Modality Therapy; Cyclosporine; Humans; Methotrexate; Psoriasis; PUVA Therapy; Retinoids; Tars; Ultraviolet Therapy; Vitamin D | 1993 |
[Pustular psoriasis and psoriasis vulgaris].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Child; Child, Preschool; Etretinate; Female; Humans; Infant; Japan; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; PUVA Therapy; Sex Factors | 1993 |
Methotrexate hepatotoxicity and the role of routine liver biopsy: a collective opinion.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Humans; Liver; Methotrexate; Psoriasis | 1995 |
Hazards of low dose methotrexate.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Methotrexate; Psoriasis | 1995 |
Methotrexate and other chemotherapeutic agents used to treat psoriasis.
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; Dermatologic Agents; Drug Combinations; Drug Monitoring; Humans; Immunosuppressive Agents; Methotrexate; Photochemotherapy; Psoriasis | 1995 |
Erosion of psoriatic plaques: an early sign of methotrexate toxicity.
Topics: Adult; Dermatologic Agents; Drug Eruptions; Female; Humans; Methotrexate; Middle Aged; Psoriasis | 1996 |
Review article: methotrexate in gastroenterology--dangerous villain or simply misunderstood?
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Gastroenterology; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Methotrexate; Psoriasis | 1996 |
Methotrexate update.
Topics: Antidotes; Antirheumatic Agents; Arthritis, Rheumatoid; Dermatologic Agents; Drug Therapy, Combination; Folic Acid; Hematinics; Humans; Kidney; Leucovorin; Liver; Lung; Methotrexate; Psoriasis | 1996 |
[Systemic therapy of psoriasis].
Topics: Acitretin; Cyclosporine; Dermatologic Agents; Fumarates; Glucocorticoids; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Photochemotherapy; Phototherapy; Psoriasis | 1996 |
Failure of combination therapy with acitretin and cyclosporin A in 3 patients with erythrodermic psoriasis.
Topics: Acitretin; Aged; Aged, 80 and over; Calcitriol; Cyclosporine; Dermatitis, Exfoliative; Dermatologic Agents; Drug Combinations; Humans; Immunosuppressive Agents; Keratolytic Agents; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis | 1997 |
[Non-cancer uses of methotrexate].
Topics: Adult; Aged; Anti-Asthmatic Agents; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Asthma; Child; Contraindications; Dermatologic Agents; Drug Tolerance; Humans; Methotrexate; Psoriasis | 1996 |
Methotrexate for psoriasis.
Topics: Contraindications; Dermatologic Agents; Drug Monitoring; Humans; Methotrexate; Psoriasis | 1996 |
Combined topical calcipotriene ointment 0.005% and various systemic therapies in the treatment of plaque-type psoriasis vulgaris: review of the literature and results of a survey sent to 100 dermatologists.
Topics: Acitretin; Administration, Topical; Calcitriol; Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Drug Synergism; Drug Therapy, Combination; Etretinate; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Ointments; Phototherapy; Psoriasis; Risk; Safety; Treatment Outcome | 1997 |
Methotrexate use in psoriasis and psoriatic arthritis.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Drug Monitoring; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1997 |
Systemic treatment of severe psoriasis.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Phototherapy; Prognosis; Psoriasis; Retinoids; Severity of Illness Index | 1997 |
Methotrexate in psoriasis: consensus conference.
Topics: Dermatologic Agents; Drug Interactions; Humans; Liver Diseases; Methotrexate; Psoriasis | 1998 |
Methotrexate hepatotoxicity: what is the evidence?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis; Risk Assessment | 1998 |
Acitretin combination therapy.
Topics: Acitretin; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Humans; Keratolytic Agents; Methotrexate; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1999 |
Systemic sequential therapy of psoriasis: a new paradigm for improved therapeutic results.
Topics: Acitretin; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Keratolytic Agents; Methotrexate; Psoriasis | 1999 |
[Methotrexate in dermatology: pharmacology, indications, applications and prudent use].
Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Dermatologic Agents; Drug Combinations; Folic Acid Antagonists; Follow-Up Studies; Humans; Methotrexate; Prospective Studies; Psoriasis; Retrospective Studies; Risk Factors; Skin Diseases; Skin Neoplasms | 1999 |
Methotrexate.
Topics: Antimetabolites, Antineoplastic; Bone Marrow; Dermatologic Agents; Humans; Methotrexate; Psoriasis | 1999 |
Psoriasis: current perspectives with an emphasis on treatment.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Calcitriol; Cyclosporine; Dermatologic Agents; Diagnosis, Differential; Drug Therapy, Combination; Humans; Keratolytic Agents; Methotrexate; Nicotinic Acids; Phototherapy; Psoriasis; PUVA Therapy; Retinoids; Severity of Illness Index; United States | 1999 |
Clinically significant therapeutic interactions for the practicing dermatologist.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Dermatology; Drug Interactions; Erythromycin; Humans; Methotrexate; Photosensitizing Agents; Practice Patterns, Physicians'; Psoriasis; PUVA Therapy | 1999 |
Pulmonary toxicity in a patient with psoriasis receiving methotrexate therapy.
Topics: Adult; Dermatologic Agents; Female; Folic Acid Antagonists; Forced Expiratory Volume; Humans; Methotrexate; Psoriasis; Respiration Disorders; Vital Capacity | 2000 |
Liver biopsies and methotrexate: a time for reconsideration?
Topics: Biomarkers; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Practice Guidelines as Topic; Procollagen; Psoriasis; Radionuclide Imaging | 2000 |
Management of nail psoriasis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Antifungal Agents; Cyclosporine; Dermatologic Agents; Female; Fluorouracil; Glucocorticoids; Humans; Keratosis; Male; Methotrexate; Nail Diseases; Psoriasis; Triamcinolone Acetonide | 2000 |
Systemic therapy of psoriasis using methotrexate.
Topics: Dermatologic Agents; Drug Interactions; Humans; Methotrexate; Psoriasis | 2000 |
Advances in psoriasis treatment.
Topics: Acitretin; Administration, Topical; Anthralin; Anti-Inflammatory Agents; Coal Tar; Cyclosporine; Dermatologic Agents; Glucocorticoids; Humans; Methotrexate; Nicotinic Acids; Patient Education as Topic; Phototherapy; Psoriasis; PUVA Therapy; Quality of Life; Social Support; Triamcinolone | 2000 |
Phototherapy for psoriasis.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; PUVA Therapy; Retinoids; Skin; Ultraviolet Therapy | 2001 |
Therapeutic strategies: rotational therapy and combinations.
Topics: Acitretin; Administration, Topical; Anti-Inflammatory Agents; Autoimmune Diseases; Calcitriol; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Fumarates; Glucocorticoids; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy | 2001 |
New dermatological agents for the treatment of psoriasis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Cholecalciferol; Clinical Trials as Topic; Glucocorticoids; Humans; Immunosuppressive Agents; Ligands; Methotrexate; Psoriasis; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Vitamin A | 2001 |
Treatment of psoriasis. Part 2. Systemic therapies.
Topics: Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Retinoids | 2001 |
Psoriasis in children: a guide to its diagnosis and management.
Topics: Adrenal Cortex Hormones; Age of Onset; Child; Child, Preschool; Cyclosporine; Emollients; Humans; Immunosuppressive Agents; Methotrexate; Phototherapy; Practice Guidelines as Topic; Prevalence; Psoriasis; Retinoids; Vitamin D | 2001 |
[Immunosuppressive agents for therapy of autoimmune diseases of the skin and of psoriasis].
Topics: Autoimmune Diseases; Dermatitis Herpetiformis; Dermatomyositis; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Pemphigus; Polyarteritis Nodosa; Psoriasis; Pyoderma; Scleroderma, Systemic; Skin Diseases | 1977 |
[Indications and limits of long-term therapy with immunosuppressive (and cytostatic) agents in various chronic skin diseases].
Topics: Arthritis, Reactive; Azathioprine; Chronic Disease; Cyclophosphamide; Dermatomyositis; Humans; Immunosuppressive Agents; Impetigo; Long-Term Care; Lupus Erythematosus, Discoid; Methotrexate; Pemphigus; Penicillamine; Polyarteritis Nodosa; Prednisolone; Psoriasis; Pyoderma; Scleroderma, Systemic; Skin Diseases; Wissler's Syndrome | 1977 |
Methotrexate.
Topics: Chemical and Drug Induced Liver Injury; Ficusin; Humans; Methotrexate; Psoriasis; Ultraviolet Therapy | 1977 |
Psoriasis: current concepts in management.
Topics: Administration, Topical; Adrenal Cortex Hormones; Age Factors; Anthralin; Ficusin; Glycogen; Hair; Humans; Hydroxyurea; Methotrexate; Mitosis; Mucous Membrane; Nails; Psoriasis; Skin; Tars; Tretinoin; Ultraviolet Therapy | 1977 |
[Psoriatic arthritis].
Topics: Adult; Amyloidosis; Anthracenes; Arthritis; Arthritis, Reactive; Diagnosis, Differential; Exercise Therapy; Female; HLA Antigens; Humans; Hydrotherapy; Male; Metacarpus; Methotrexate; Myositis; Nails; Psoriasis; Spine; Spondylitis, Ankylosing; Synovitis | 1977 |
Cytokinetics and chemotherapy of psoriasis.
Topics: Administration, Topical; Animals; Disease Models, Animal; Drug Administration Schedule; Humans; Kinetics; Methotrexate; Mice; Mice, Nude; Psoriasis; Skin Absorption | 1976 |
An appraisal of current systemic chemotherapy for psoriasis.
Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azauridine; Cell Division; Female; Humans; Hydroxyurea; Kinetics; Methotrexate; Methoxsalen; Mycophenolic Acid; Psoriasis; Ultraviolet Therapy | 1976 |
[Internal treatment of psoriasis--a review].
Topics: Arsenic; DNA; Ficusin; Glucocorticoids; Humans; Methotrexate; Psoriasis; Ultraviolet Therapy | 1976 |
[The treatment of psoriasis].
Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Coal Tar; Ficusin; Glucocorticoids; Humans; Methotrexate; Physical Therapy Modalities; Psoriasis; Psychotherapy; Resins, Plant; Ultraviolet Therapy; Vitamin A; Vitamins | 1976 |
Psoriasis: a review. II.
Topics: Adrenal Cortex Hormones; Anthralin; Azathioprine; Azauridine; Fluorouracil; Humans; Hydroxyurea; Lomustine; Mechlorethamine; Methotrexate; Psoriasis; Tars; Tretinoin; Ultraviolet Therapy | 1975 |
Chemotherapy of psoriasis.
Topics: Azauridine; Central Nervous System; Digestive System; Hematopoietic System; Humans; Hydroxyurea; Liver; Methotrexate; Mycophenolic Acid; Psoriasis | 1975 |
Megaloblastic anemia associated with psoriasis: case report and review of the literature.
Topics: Aged; Anemia, Megaloblastic; Folic Acid Deficiency; Humans; Male; Methotrexate; Psoriasis | 1992 |
Histamine and histamine type-2 receptor antagonists in psoriasis. Mechanisms and speculations.
Topics: Cyclosporine; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Humans; Methotrexate; Psoriasis; Ranitidine | 1991 |
Phototherapy and photochemotherapy.
Topics: Dermatitis, Atopic; Humans; Methotrexate; Mycosis Fungoides; Photochemotherapy; Phototherapy; Psoriasis; PUVA Therapy; Skin Diseases; Skin Neoplasms; Ultraviolet Therapy | 1992 |
[Thirty years of methotrexate treatment for psoriasis].
Topics: Humans; Methotrexate; Psoriasis | 1991 |
Guidelines for management of patients with psoriasis. Workshop of the Research Unit of the Royal College of Physicians of London; Department of Dermatology, University of Glasgow; British Association of Dermatologists.
Topics: Adrenal Cortex Hormones; Azathioprine; Cyclosporins; Humans; Hydroxyurea; Methotrexate; Phototherapy; Psoriasis; Retinoids; Skin | 1991 |
Methotrexate side-effects.
Topics: Adult; Aged; Child; Drug Interactions; Female; Hematopoiesis; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Patient Education as Topic; Pregnancy; Psoriasis; Skin Diseases | 1990 |
The practical use of methotrexate in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1990 |
The treatment of psoriasis.
Topics: Administration, Oral; Administration, Topical; Anthralin; Anti-Inflammatory Agents; Bed Rest; Chronic Disease; Coal Tar; Combined Modality Therapy; Emollients; Fluorouracil; Glucocorticoids; Humans; Mechlorethamine; Methotrexate; Patient Acceptance of Health Care; Phototherapy; Psoriasis; Retinoids; Ultraviolet Therapy | 1990 |
Monocyte and neutrophil chemotaxis in psoriasis. Clinical and experimental studies.
Topics: Chemotaxis, Leukocyte; Humans; Methotrexate; Monocytes; Neutrophils; Propionates; Psoriasis | 1989 |
[Methotrexate in rheumatic practice].
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Liver; Lung; Methotrexate; Psoriasis | 1989 |
Cytotoxic drugs: their clinical application to the rheumatic diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Depression, Chemical; Dermatomyositis; Drug Evaluation; Female; Fertility; Gastrointestinal Diseases; Granulomatosis with Polyangiitis; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Myositis; Neoplasms; Polyarteritis Nodosa; Psoriasis; Pulmonary Fibrosis; Rheumatic Diseases | 1986 |
[Treatment of erythrodermic and pustulous psoriasis with a combination of methotrexate and etretinate].
Topics: Adult; Dermatitis, Exfoliative; Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Skin Diseases, Vesiculobullous | 1988 |
Methotrexate in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1988 |
Methotrexate in psoriasis: revised guidelines.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Humans; Liver; Liver Diseases; Methotrexate; Patient Education as Topic; Psoriasis | 1988 |
Psoriasis.
Topics: Etretinate; Humans; Hydroxyurea; Methotrexate; Psoriasis; PUVA Therapy; Skin; Steroids; Ultraviolet Therapy | 1986 |
ABC of dermatology. Treatment of psoriasis.
Topics: Administration, Topical; Anthralin; Coal Tar; Etretinate; Humans; Methotrexate; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1987 |
Combination phototherapy--a critical appraisal.
Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anthralin; Coal Tar; Combined Modality Therapy; Etretinate; Evaluation Studies as Topic; Humans; Methotrexate; Mice; Photochemotherapy; Psoriasis; PUVA Therapy; Retinoids; Ultraviolet Therapy | 1986 |
Cytotoxic agents for use in dermatology. I.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemical Phenomena; Chemistry; Humans; Methotrexate; Psoriasis; Skin Diseases; Vinca Alkaloids | 1985 |
Mechanisms of action and clinical applications of cytotoxic drugs in rheumatic disorders.
Topics: Arthritis, Reactive; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Collagen Diseases; Cyclophosphamide; Dermatomyositis; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Neoplasms; Psoriasis; Vasculitis | 1985 |
PUVA combination therapy.
Topics: Adrenal Cortex Hormones; Anthralin; Combined Modality Therapy; Humans; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Retinoids; Skin Diseases; Ultraviolet Therapy | 1985 |
Clinical pharmacokinetics of methotrexate in psoriasis therapy.
Topics: Bile; Biological Availability; Drug Administration Schedule; Erythrocytes; Folic Acid; Folic Acid Antagonists; Humans; Intestinal Absorption; Kidney; Kinetics; Liver; Methotrexate; Psoriasis; Skin | 1985 |
Clinical pharmacology of very low dose methotrexate for use in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Bile; Biological Availability; Brain; Breast Neoplasms; Cell Line; Half-Life; Humans; Intestinal Absorption; Kidney; Kinetics; Liver; Metabolic Clearance Rate; Methotrexate; Neoplasms; Psoriasis; Tritium | 1985 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Gold; Humans; Immunosuppression Therapy; Methotrexate; Pancytopenia; Penicillamine; Placebos; Psoriasis | 1985 |
Longterm methotrexate therapy in rheumatoid arthritis: a review.
Topics: Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Drug Resistance; Gold; Humans; Hydroxychloroquine; Liver Diseases; Liver Function Tests; Methotrexate; Penicillamine; Prednisone; Psoriasis; Risk | 1985 |
Toxicity of low dose methotrexate in rheumatoid arthritis.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases | 1985 |
[Some developments in psoriasis research abroad].
Topics: Aza Compounds; Female; Humans; Hydroxyurea; Male; Mechlorethamine; Methotrexate; Psoriasis; Uridine | 1974 |
[Dermatological news from America. I].
Topics: Acne Vulgaris; Adolescent; Adult; Aged; Anti-Bacterial Agents; Autoimmune Diseases; Blister; Child; Child, Preschool; Dermatitis, Contact; Drug Hypersensitivity; Female; Herpes Zoster; Humans; Hypersensitivity, Delayed; Keratosis; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nevus; Pemphigus; Phobic Disorders; Prednisone; Psoriasis; Skin Diseases; Skin Diseases, Infectious; Skin Neoplasms; Sunburn; Tuberculosis, Cutaneous; United States; Virus Diseases; Xanthomatosis | 1970 |
Advances in the treatment of diseases of the skin.
Topics: Acne Vulgaris; Alopecia Areata; Dermatitis, Contact; Humans; Lupus Erythematosus, Systemic; Lymphatic Diseases; Methotrexate; Ointments; Photosensitivity Disorders; Porphyrias; Psoriasis; Rosacea; Skin Diseases; Steroids; Sunscreening Agents; Tetracycline; Tinea; Trichophyton; Urea; Vitiligo | 1971 |
[What is new in American dermatology. I].
Topics: Acne Vulgaris; Adult; Aged; Angiomatosis; Cutis Laxa; Dermatitis; Epidermolysis Bullosa; Female; Humans; Keratosis; Male; Methotrexate; Nevus, Pigmented; Osteochondrodysplasias; Pemphigus; Photosensitivity Disorders; Psoriasis; Skin Diseases; Skin Neoplasms; Stevens-Johnson Syndrome; Vitiligo | 1971 |
Cytotoxic drugs in treatment of nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immune Complex Diseases; Immunosuppressive Agents; Infections; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Nephrotic Syndrome; Ophthalmia, Sympathetic; Psoriasis; Thioguanine; Uveitis | 1972 |
[Treatment of psoriasis].
Topics: Adrenocorticotropic Hormone; Aminopterin; Chloroquine; Dexamethasone; Diet Therapy; Flumethasone; Glucocorticoids; Humans; Methotrexate; Prednisolone; Prodigiosin; Psoriasis; Pyrogens; Triamcinolone; Vitamins | 1972 |
Juvenile generalized pustular psoriasis. A report of five cases and a review of the literature.
Topics: Adrenocorticotropic Hormone; Child; Child, Preschool; Dermatitis, Seborrheic; Dermatologic Agents; Female; Humans; Infant; Male; Methotrexate; Ointments; Prognosis; Psoriasis; Remission, Spontaneous; Stress, Psychological; Triamcinolone | 1972 |
Antimetabolites and psoriasis.
Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Arsenic; Humans; Hydroxyurea; Methotrexate; Mice; Neoplasms; Nucleic Acids; Protein Biosynthesis; Psoriasis; Time Factors; Ultraviolet Rays | 1972 |
[Therapy of psoriasis].
Topics: Adrenal Cortex Hormones; Anthracenes; Anti-Infective Agents, Local; Humans; Lactones; Methotrexate; Physical Therapy Modalities; Psoriasis; Triamcinolone; Vitamin A | 1972 |
Methotrexate in the treatment of psoriasis.
Topics: Abnormalities, Drug-Induced; Bone Marrow; Chemical and Drug Induced Liver Injury; Female; Hematologic Diseases; Humans; Kidney Diseases; Leucovorin; Liver; Methotrexate; Pregnancy; Psoriasis; Skin | 1972 |
The action of antimetabolites in the skin: methotrexate for psoriasis.
Topics: Carcinoma, Basal Cell; Cell Division; DNA; Fluorouracil; Humans; Injections, Intradermal; Keratosis; Methotrexate; Mitosis; Psoriasis; Skin Diseases; Tritium | 1972 |
Cytokinetics in diseases of epidermal hyperplasia.
Topics: Cell Division; Female; Humans; Hyperplasia; Ichthyosis; Keratosis; Kinetics; Melanoma; Methotrexate; Psoriasis; Skin; Skin Diseases; Skin Neoplasms; Uterine Cervical Neoplasms | 1973 |
Psoriasis.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Antimetabolites; Child; Female; Humans; Hydroxyurea; Hyperplasia; Injections, Intramuscular; Injections, Intravenous; Keratosis; Male; Methotrexate; Psoriasis; Psychophysiologic Disorders; Tars; Ultraviolet Therapy | 1973 |
Drug therapy: immunosuppressive agents (second of two parts).
Topics: Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Child; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Psoriasis; Purines; Sulfhydryl Compounds | 1973 |
[Immunosuppressive drugs in the treatment of diseases belonging to the psoriasis group].
Topics: Administration, Oral; Adrenal Cortex Hormones; Autoantibodies; Humans; Hydroxyurea; Immunosuppressive Agents; Injections, Intramuscular; Injections, Intravenous; Liver; Male; Methotrexate; Psoriasis; Skin; Spermatogenesis | 1974 |
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Mice; Mice, Inbred NZB; Multiple Sclerosis; Nephritis; Nephrosis; Nitrogen Mustard Compounds; Penicillins; Psoriasis; Uveitis, Anterior | 1973 |
Psoriasis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Antimetabolites; Aza Compounds; Glucocorticoids; Humans; Hydroxyurea; Methotrexate; Psoriasis; Salicylates; Tars; Uridine | 1974 |
[Psoriasis vulgaris. Internal therapy].
Topics: Arsenic; Bromine; Cortisone; Folic Acid Antagonists; Humans; Indomethacin; Methotrexate; Psoriasis; Vitamin D | 1966 |
A current review of psoriasis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Arthritis; Dosage Forms; Female; Humans; Hyperplasia; Kinetics; Male; Methotrexate; Middle Aged; Psoriasis; Sex Factors; Skin; Steroids; Triamcinolone; Vitamins; Wounds and Injuries | 1968 |
[What is new in American dermatology. II].
Topics: Adult; Carcinoma, Basal Cell; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Methotrexate; Psoriasis; Pyoderma; Skin Diseases; Skin Neoplasms | 1968 |
[Amyloidosis in chronic rheumatic diseases].
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biopsy; Chloroquine; Chronic Disease; Collagen Diseases; Felty Syndrome; Female; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Proteinuria; Psoriasis; Rectum; Rheumatic Diseases; Sjogren's Syndrome; Spondylitis, Ankylosing | 1968 |
Methotrexate and the liver.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Hepatomegaly; Humans; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis; Splenomegaly | 1969 |
[Methylaminopterin (Methotrexate) in the treatment of psoriasis. A review].
Topics: Age Factors; Blood Cell Count; Chronic Disease; Female; Folic Acid Antagonists; Humans; Kidney Function Tests; Liver Function Tests; Male; Methotrexate; Psoriasis; Time Factors | 1969 |
Methotrexate and its uses in dermatology.
Topics: Arthritis, Reactive; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatomyositis; Humans; Keratoacanthoma; Keratosis; Methotrexate; Mycosis Fungoides; Pemphigus; Pityriasis Rubra Pilaris; Psoriasis; Sarcoma, Kaposi; Skin Diseases; Skin Neoplasms | 1970 |
Some hazards of methotrexate treatment of psoriasis.
Topics: Abnormalities, Drug-Induced; Acute Kidney Injury; Brain; Child; Female; Humans; Immunosuppressive Agents; Kidney; Liver; Male; Methotrexate; Pregnancy; Psoriasis | 1970 |
[Current knowledge on the pathogenesis of common psoriasis as the basis for a scientifically founded therapy. II. Therapeutic possibilities and pathogenetic principles of antipsoriatic drugs].
Topics: Anthracenes; Arsenic; Baths; Glucocorticoids; Humans; Mercury; Methotrexate; Psoriasis; Salicylates; Tars; Ultraviolet Therapy | 1970 |
[Cytostatic drugs in the therapy of psoriasis].
Topics: Alkylating Agents; Aminopterin; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Humans; Hydroxyurea; Methotrexate; Podophyllin; Psoriasis; Purines; Pyrimidines; Skin; Vinblastine; Vincristine | 1971 |
Drug reactions XV. Methotrexate, psoriasis and the liver.
Topics: Alcohol Drinking; Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 1971 |
133 trial(s) available for methotrexate and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Comparison of the clinical efficacy of subcutaneous vs. oral administration of methotrexate in patients with psoriasis vulgaris: a randomized controlled trial.
Topics: Administration, Oral; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Single-Blind Method; Treatment Outcome | 2022 |
Adalimumab with Methotrexate vs. Adalimumab Monotherapy in Psoriasis: First-Year Results of a Single-Blind Randomized Controlled Trial.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Methotrexate; Psoriasis; Single-Blind Method; Treatment Outcome | 2022 |
Internet-based survey intervention improves adherence to methotrexate among psoriasis patients.
Topics: Humans; Internet; Medication Adherence; Methotrexate; Patient Compliance; Psoriasis; Severity of Illness Index | 2022 |
Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5-fluorouracil, and methotrexate in the treatment of nail psoriasis: A comparative study.
Topics: Calcitriol; Dermatologic Agents; Fluorouracil; Humans; Injections, Intralesional; Methotrexate; Nail Diseases; Psoriasis; Treatment Outcome; Triamcinolone Acetonide; Urea | 2022 |
Comparison of overall efficacy and safety of oral versus subcutaneous methotrexate in severe psoriasis.
Topics: Adult; Chronic Disease; Humans; Methotrexate; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome | 2022 |
Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial.
Topics: Adult; Arthritis, Rheumatoid; COVID-19; COVID-19 Vaccines; Female; Humans; Immunization, Secondary; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2022 |
Adalimumab combined with methotrexate versus adalimumab monotherapy in psoriasis: Three-year follow-up data of a single-blind randomized controlled trial.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Methotrexate; Psoriasis; Single-Blind Method; Treatment Outcome | 2023 |
Effectiveness and survival of methotrexate versus adalimumab in patients with moderate-to-severe psoriasis: a cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).
Topics: Adalimumab; Adjuvants, Immunologic; Adult; Biological Factors; Biological Products; Cohort Studies; Dermatologists; Etanercept; Female; Humans; Immunologic Factors; Male; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2023 |
Effects of Interleukin 17A Inhibition on Myocardial Deformation and Vascular Function in Psoriasis.
Topics: Antibodies, Monoclonal, Humanized; Biomarkers; Brachial Artery; Cyclosporine; Echocardiography; Female; Heart Ventricles; Humans; Immunosuppressive Agents; Interleukin-17; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Pulse Wave Analysis; Vascular Stiffness; Ventricular Function, Left | 2020 |
Etanercept biosimilar (recombinant human tumor necrosis factor-α receptor II: IgG Fc fusion protein) and methotrexate combination therapy in Chinese patients with moderate-to-severe plaque psoriasis: a multicentre, randomized, double-blind, placebo-contro
Topics: Adult; Biosimilar Pharmaceuticals; China; Double-Blind Method; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Etanercept; Female; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Male; Methotrexate; Middle Aged; Placebos; Psoriasis; Receptors, Tumor Necrosis Factor, Type II; Recombinant Fusion Proteins; Severity of Illness Index; Treatment Outcome | 2020 |
Iontophoretic delivery of methotrexate in the treatment of palmar psoriasis: A randomised controlled study.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents; Calcitriol; Female; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome | 2020 |
Evaluating the efficacy of ursodeoxycholic acid plus methotrexate vs methotrexate alone in the treatment of moderate to severe plaque-type psoriasis: A randomized clinical trial.
Topics: Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome; Ursodeoxycholic Acid | 2020 |
Efficacy of oral methotrexate (MTX) monotherapy vs oral MTX plus narrowband ultraviolet light B phototherapy in palmoplantar psoriasis.
Topics: Humans; Methotrexate; Psoriasis; Treatment Outcome; Ultraviolet Rays; Ultraviolet Therapy | 2020 |
Treatment of nail psoriasis with intramatrical methotrexate: An uncontrolled prospective study of 20 patients.
Topics: Adult; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Injections, Intralesional; Male; Methotrexate; Nail Diseases; Nails; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome; Young Adult | 2021 |
Methotrexate vs secukinumab safety in psoriasis patients with metabolic syndrome.
Topics: Antibodies, Monoclonal, Humanized; Female; Humans; Male; Metabolic Syndrome; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2020 |
TST conversions and systemic interferon-gamma increase after methotrexate introduction in psoriasis patients.
Topics: Adult; C-Reactive Protein; Female; Humans; Immunosuppressive Agents; Interferon-gamma; Latent Tuberculosis; Male; Mass Screening; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Tuberculin Test; Tumor Necrosis Factor-alpha; Young Adult | 2020 |
Safety and efficacy profile of oral cyclosporine vs oral methotrexate vs oral acitretin in palmoplantar psoriasis: A hospital based prospective investigator blind randomized controlled comparative study.
Topics: Acitretin; Cyclosporine; Hospitals; Humans; Methotrexate; Prospective Studies; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2021 |
The impact of methotrexate therapy with vitamin D supplementation on the cardiovascular risk factors among patients with psoriasis; a prospective randomized comparative study.
Topics: C-Reactive Protein; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cholesterol; Dietary Supplements; Heart Disease Risk Factors; Humans; Lipids; Methotrexate; Prospective Studies; Psoriasis; Triglycerides; Vitamin D | 2022 |
Comparison of the Efficacy and Safety of Apremilast and Methotrexate in Patients with Palmoplantar Psoriasis: A Randomized Controlled Trial.
Topics: Adult; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Severity of Illness Index; Thalidomide; Treatment Outcome | 2021 |
Evaluation of psoriasis severity and inflammatory responses under concomitant treatment with methotrexate plus micronutrients for psoriasis vulgaris: a randomized double blind trial.
Topics: Adult; Aged; Dermatologic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Interleukin-1beta; Male; Methotrexate; Micronutrients; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2017 |
Efficacy and safety of adalimumab every other week versus methotrexate once weekly in children and adolescents with severe chronic plaque psoriasis: a randomised, double-blind, phase 3 trial.
Topics: Adalimumab; Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Adalimumab for treating childhood plaque psoriasis: a clinical trial evaluation.
Topics: Adalimumab; Administration, Oral; Antibodies, Monoclonal, Humanized; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Quality of Life; Tumor Necrosis Factor-alpha | 2017 |
Evaluation of oxidative stress via protein expression of glutathione S-transferase and cytochrome p450 (CYP450) ısoenzymes in psoriasis vulgaris patients treated with methotrexate.
Topics: Adolescent; Adult; Cytochrome P-450 Enzyme System; Dermatologic Agents; Female; Glutathione Transferase; Humans; Isoenzymes; Male; Methotrexate; Middle Aged; Oxidative Stress; Psoriasis; Young Adult | 2018 |
Poor early response to methotrexate portends inadequate long-term outcomes in patients with moderate-to-severe psoriasis: Evidence from 2 phase 3 clinical trials.
Topics: Adult; Dermatologic Agents; Female; Humans; Male; Methotrexate; Models, Statistical; Prognosis; Psoriasis; Severity of Illness Index; Time Factors; Treatment Outcome | 2017 |
Novel methotrexate soft nanocarrier/fractional erbium YAG laser combination for clinical treatment of plaque psoriasis.
Topics: Adolescent; Adult; Combined Modality Therapy; Drug Carriers; Female; Humans; Lasers, Solid-State; Male; Methotrexate; Middle Aged; Nanostructures; Psoriasis; Young Adult | 2018 |
Can etanercept treatment failure in moderate-to-severe psoriasis be overcome by addition of low-dose methotrexate? A single-center experience.
Topics: Adult; Aged; Body Surface Area; Child; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Failure; Young Adult | 2018 |
A prospective, clinical, nonrandomized controlled trial of individualized, nurse-led patient-centred intervention in patients with psoriasis.
Topics: Adult; Behavior Therapy; Biological Products; Combined Modality Therapy; Denmark; Female; Humans; Male; Methotrexate; Middle Aged; Nurse-Patient Relations; Patient-Centered Care; Phototherapy; Practice Patterns, Nurses'; Prospective Studies; Psoriasis; Quality of Life; Referral and Consultation; Treatment Outcome | 2019 |
Ustekinumab Safety in Psoriasis, Psoriatic Arthritis, and Crohn's Disease: An Integrated Analysis of Phase II/III Clinical Development Programs.
Topics: Adult; Antibodies, Monoclonal; Arthritis, Psoriatic; Crohn Disease; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome; Ustekinumab | 2019 |
Clinical response of psoriasis to subcutaneous methotrexate correlates with inhibition of cutaneous T helper 1 and 17 inflammatory pathways.
Topics: Adult; Biopsy; Cytokines; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Placebos; Prospective Studies; Psoriasis; Signal Transduction; Skin; Th1 Cells; Th17 Cells; Treatment Outcome | 2019 |
Sustained long-term efficacy and safety of adalimumab in paediatric patients with severe chronic plaque psoriasis from a randomized, double-blind, phase III study.
Topics: Adalimumab; Adolescent; Biological Factors; Child; Child, Preschool; Chronic Disease; Double-Blind Method; Female; Humans; Long-Term Care; Male; Methotrexate; Psoriasis; Severity of Illness Index; Time Factors; Treatment Outcome | 2019 |
TT genotype of rs10036748 in TNIP1 shows better response to methotrexate in a Chinese population: a prospective cohort study.
Topics: Adult; Aged; Asian People; China; Dermatologic Agents; DNA-Binding Proteins; Drug Resistance; Female; Genetic Predisposition to Disease; Genotyping Techniques; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome | 2019 |
Efficacy and safety of etanercept combined plus methotrexate and comparison of expression of pro-inflammatory factors expression for the treatment of moderate-to-severe plaque psoriasis.
Topics: Adult; Aged; Cytokines; Drug Therapy, Combination; Etanercept; Female; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome | 2019 |
A 24-week multicentre, randomized, open-label, parallel-group study comparing the efficacy and safety of ixekizumab vs. fumaric acid esters and methotrexate in patients with moderate-to-severe plaque psoriasis naive to systemic treatment.
Topics: Antibodies, Monoclonal, Humanized; Double-Blind Method; Fumarates; Germany; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2020 |
Comparative efficacy of hydroxyurea and methotrexate in treating psoriasis.
Topics: Adolescent; Adult; Bangladesh; Dermatologic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome; Young Adult | 2013 |
Antiangiogenic effect of methotrexate and PUVA on psoriasis.
Topics: Adolescent; Adult; Angiogenesis Inhibitors; Blood Circulation; Capillaries; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Treatment Outcome; Young Adult | 2013 |
One-year safety and efficacy of ustekinumab and results of dose adjustment after switching from inadequate methotrexate treatment: the TRANSIT randomized trial in moderate-to-severe plaque psoriasis.
Topics: Antibodies, Monoclonal, Humanized; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Substitution; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Ustekinumab | 2014 |
Transition to ustekinumab in patients with moderate-to-severe psoriasis and inadequate response to methotrexate: a randomized clinical trial (TRANSIT).
Topics: Antibodies, Monoclonal, Humanized; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Substitution; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Ustekinumab | 2014 |
Association of disease severity with IL-1 levels in methotrexate-treated psoriasis patients.
Topics: Adolescent; Adult; Aged; Cell Differentiation; Female; Humans; Interleukin-1alpha; Interleukin-1beta; Male; Methotrexate; Middle Aged; Psoriasis; Skin; Th17 Cells; Treatment Outcome; Young Adult | 2013 |
Effect of treatment on prolactin levels in patients with psoriasis vulgaris.
Topics: Female; Humans; Male; Methotrexate; Prolactin; Psoriasis | 2014 |
Changes in C-reactive protein in patients with moderate-to-severe psoriasis switched to adalimumab therapy after suboptimal response to etanercept, methotrexate or phototherapy.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; C-Reactive Protein; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index | 2014 |
Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, m
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Psoriatic; Certolizumab Pegol; Cross-Over Studies; Double-Blind Method; Etanercept; Female; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Infliximab; Interleukin-12 Subunit p40; Male; Methotrexate; Middle Aged; Polyethylene Glycols; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Failure; Treatment Outcome; Tumor Necrosis Factor-alpha; Ustekinumab | 2014 |
Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor.
Topics: Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Phosphodiesterase 4 Inhibitors; Psoriasis; Thalidomide; Treatment Outcome | 2014 |
Comparative study of the effect of narrowband ultraviolet B phototherapy plus methotrexate vs. narrowband ultraviolet B alone and methotrexate alone in the treatment of plaque-type psoriasis.
Topics: Adult; Combined Modality Therapy; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Ultraviolet Therapy; Young Adult | 2014 |
Analysis of body regions and components of PASI scores during adalimumab or methotrexate treatment for patients with moderate-to-severe psoriasis.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Dermatologic Agents; Double-Blind Method; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Time Factors; Treatment Outcome | 2014 |
The efficacy of methotrexate plus pioglitazone vs. methotrexate alone in the management of patients with plaque-type psoriasis: a single-blinded randomized controlled trial.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pioglitazone; Prospective Studies; Psoriasis; Quality of Life; Severity of Illness Index; Single-Blind Method; Thiazolidinediones; Young Adult | 2015 |
CCL20 and IL22 Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis: A Randomized Clinical Trial.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Chemokine CCL20; Down-Regulation; Female; Humans; Interleukin-22; Interleukins; Male; Methotrexate; Middle Aged; Psoriasis; RNA, Messenger; Single-Blind Method; T-Lymphocytes, Helper-Inducer; Treatment Outcome; Young Adult | 2015 |
Effect of etanercept therapy on psoriasis symptoms in patients from Latin America, Central Europe, and Asia: a subset analysis of the PRISTINE trial.
Topics: Adrenal Cortex Hormones; Adult; Asia; Dermatologic Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Europe; Female; Humans; Latin America; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor | 2015 |
Efficacy of Adalimumab Compared With Methotrexate or Placebo Stratified by Baseline BMI in a Randomized Placebo-Controlled Trial in Patients With Psoriasis.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Dermatologic Agents; Female; Humans; Ideal Body Weight; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2015 |
Methotrexate normalized keratinocyte activation cycle by overturning abnormal keratins as well as deregulated inflammatory mediators in psoriatic patients.
Topics: Adolescent; Adult; Aged; Cell Cycle; Down-Regulation; Female; Humans; Inflammation Mediators; Keratinocytes; Keratins; Male; Methotrexate; Middle Aged; Psoriasis; Young Adult | 2015 |
Adalimumab Efficacy in Patients with Psoriasis Who Received or Did Not Respond to Prior Systemic Therapy: A Pooled Post Hoc Analysis of Results from Three Double-Blind, Placebo-Controlled Clinical Trials.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Biological Products; Cyclosporine; Double-Blind Method; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Severity of Illness Index; Treatment Outcome | 2016 |
Pharmacokinetic profile of methotrexate in psoriatic skin via the oral or subcutaneous route using dermal microdialysis showing higher methotrexate bioavailability in psoriasis plaques than in non-lesional skin.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Dermatologic Agents; Humans; Injections, Subcutaneous; Methotrexate; Microdialysis; Middle Aged; Psoriasis | 2016 |
Clinical efficacy of platelet rich plasma in combination with methotrexate in chronic plaque psoriatic patients.
Topics: Adolescent; Adult; Chronic Disease; Female; Humans; Immunosuppressive Agents; India; Injections, Intralesional; Male; Methotrexate; Middle Aged; Pilot Projects; Platelet-Rich Plasma; Prospective Studies; Psoriasis; Remission Induction; Skin; Time Factors; Treatment Outcome; Young Adult | 2016 |
Quality of life and patient benefit following transition from methotrexate to ustekinumab in psoriasis.
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis; Quality of Life; Ustekinumab | 2017 |
An intensified dosing schedule of subcutaneous methotrexate in patients with moderate to severe plaque-type psoriasis (METOP): a 52 week, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedule; Humans; Immunosuppressive Agents; Injections, Subcutaneous; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Treatment Outcome; Young Adult | 2017 |
The objective Psoriasis Area and Severity Index: a randomized controlled pilot study comparing the effectiveness of ciclosporin and methotrexate.
Topics: Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Pilot Projects; Psoriasis; Treatment Outcome | 2017 |
Optimizing adalimumab treatment in psoriasis with concomitant methotrexate (OPTIMAP): study protocol for a pragmatic, single-blinded, investigator-initiated randomized controlled trial.
Topics: Adalimumab; Biological Products; Clinical Protocols; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Netherlands; Psoriasis; Quality of Life; Remission Induction; Research Design; Severity of Illness Index; Single-Blind Method; Skin; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
A multicenter, open-label study of repeat courses of intramuscular alefacept in combination with other psoriasis therapies in patients with chronic plaque psoriasis.
Topics: Adult; Alefacept; CD4 Lymphocyte Count; Cyclosporine; Dermatologic Agents; Drug Administration Routes; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunologic Factors; Immunosuppressive Agents; Infections; Lymphopenia; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Recombinant Fusion Proteins; Retinoids; Retreatment; Treatment Outcome; Ultraviolet Therapy | 2008 |
The combination of etanercept and methotrexate increases the effectiveness of treatment in active psoriasis despite inadequate effect of methotrexate therapy.
Topics: Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pilot Projects; Psoriasis; Quality of Life; Receptors, Tumor Necrosis Factor; Severity of Illness Index | 2008 |
Good clinical response to anti-psoriatic treatment with adalimumab and methotrexate does not inflict a direct effect on compartmentalization of T-cell subsets: a pilot study.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cell Compartmentation; Dermatologic Agents; Female; Humans; Lymphocyte Count; Male; Methotrexate; Middle Aged; Pilot Projects; Psoriasis; T-Lymphocytes | 2008 |
Methotrexate versus traditional Chinese medicine in psoriasis: a randomized, placebo-controlled trial to determine efficacy, safety and quality of life.
Topics: Adult; Aged; Aged, 80 and over; Dermatologic Agents; Disability Evaluation; Double-Blind Method; Drugs, Chinese Herbal; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2010 |
Methotrexate/narrowband UVB phototherapy combination vs. narrowband UVB phototherapy in the treatment of chronic plaque-type psoriasis--a randomized single-blinded placebo-controlled study.
Topics: Adult; Female; Humans; Male; Methotrexate; Middle Aged; Photochemotherapy; Placebos; Prospective Studies; Psoriasis; Single-Blind Method | 2010 |
Efficacy and safety of mycophenolate mofetil vs. methotrexate for the treatment of chronic plaque psoriasis.
Topics: Adolescent; Adult; Chronic Disease; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Psoriasis; Treatment Outcome; Young Adult | 2010 |
Evaluation of the efficacy of methotrexate and cyclosporine therapies on psoriatic nails: a one-blind, randomized study.
Topics: Cyclosporine; Humans; Methotrexate; Nail Diseases; Psoriasis; Single-Blind Method | 2011 |
Fumarates vs. methotrexate in moderate to severe chronic plaque psoriasis: a multicentre prospective randomized controlled clinical trial.
Topics: Adult; Female; Fumarates; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Severity of Illness Index | 2011 |
Insulin-like growth factor-1 in psoriatic plaques treated with PUVA and methotrexate.
Topics: Case-Control Studies; DNA Primers; Female; Humans; Immunosuppressive Agents; Insulin-Like Growth Factor I; Male; Methotrexate; Photochemotherapy; Polymerase Chain Reaction; Psoriasis; RNA, Messenger | 2011 |
A global approach to psoriatic patients through PASI score and Skindex-29.
Topics: Acitretin; Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Diagnostic Self Evaluation; Emotions; Etanercept; Female; Folic Acid; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Interpersonal Relations; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Quality of Life; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2011 |
Switching to adalimumab for psoriasis patients with a suboptimal response to etanercept, methotrexate, or phototherapy: efficacy and safety results from an open-label study.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Drug Resistance; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Outcome | 2011 |
Relationship between methotrexate dosing and clinical response in patients with moderate to severe psoriasis: subanalysis of the CHAMPION study.
Topics: Adult; Aged; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Treatment Outcome | 2011 |
Evaluation of liver fibrosis by transient elastography in methotrexate treated patients.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis; Logistic Models; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Sensitivity and Specificity; Single-Blind Method | 2011 |
Efficacy and safety of infliximab vs. methotrexate in patients with moderate-to-severe plaque psoriasis: results of an open-label, active-controlled, randomized trial (RESTORE1).
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Treatment Outcome; Young Adult | 2011 |
Weekly vs. daily administration of oral methotrexate (MTX) for generalized plaque psoriasis: a randomized controlled clinical trial.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Urea Nitrogen; Creatinine; Dermatologic Agents; Drug Administration Schedule; Fatigue; Female; Headache; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Nausea; Psoriasis; Severity of Illness Index; Treatment Outcome; Vomiting; Young Adult | 2011 |
A 52-week trial comparing briakinumab with methotrexate in patients with psoriasis.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Treatment Outcome | 2011 |
Weight reduction alone may not be sufficient to maintain disease remission in obese patients with psoriasis: a randomized, investigator-blinded study.
Topics: Adult; Aged; Body Mass Index; Dermatologic Agents; Diet, Reducing; Female; Humans; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Treatment Outcome; Weight Loss | 2012 |
A randomized, double-blind, placebo-controlled study to evaluate the addition of methotrexate to etanercept in patients with moderate to severe plaque psoriasis.
Topics: Administration, Cutaneous; Dermatologic Agents; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Treatment Outcome | 2012 |
Efficacy and safety of systemic methotrexate in two fixed doses of 10 mg or 25 mg orally once weekly in adult patients with severe plaque-type psoriasis: a prospective, randomized, double-blind, dose-ranging study.
Topics: Administration, Oral; Adolescent; Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Young Adult | 2012 |
Efficacy and safety of systemic methotrexate vs. acitretin in psoriasis patients with significant palmoplantar involvement: a prospective, randomized study.
Topics: Acitretin; Adolescent; Adult; Foot; Hand; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Treatment Outcome; Young Adult | 2013 |
Pharmacokinetics and pharmacodynamics of low-dose methotrexate in the treatment of psoriasis.
Topics: Adult; Aged; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 2002 |
The combination of calcipotriol and methotrexate compared with methotrexate and vehicle in psoriasis: results of a multicentre placebo-controlled randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Calcitriol; Dermatologic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Ointments; Pharmaceutical Vehicles; Psoriasis; Severity of Illness Index | 2003 |
Cyclosporin A and methotrexate are equally effective in reducing T cell numbers in psoriatic skin lesions but have no consistent effect on IFN-gamma and IL-4 expression in psoriatic skin in situ.
Topics: Adult; Aged; Cyclosporine; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Interferon-gamma; Interleukin-4; Lymphocyte Count; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; T-Lymphocytes | 2003 |
Efficacy and safety of cyclosporine versus methotrexate in severe psoriasis: a study from north India.
Topics: Adult; Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Female; Humans; India; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Treatment Outcome | 2003 |
Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis.
Topics: Adult; Chronic Disease; Cyclosporine; Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis; Quality of Life; Severity of Illness Index | 2003 |
Is methotrexate safe in the treatment of psoriatic patients?
Topics: Adolescent; Adult; Aged; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome | 2004 |
Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients.
Topics: Adult; CD4 Lymphocyte Count; Cyclosporine; Cytokines; Female; Humans; Interferon-gamma; Interleukin-4; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Th1 Cells; Th2 Cells | 2004 |
Costs of treatment in patients with moderate to severe plaque psoriasis: economic analysis in a randomized controlled comparison of methotrexate and cyclosporine.
Topics: Administration, Oral; Adult; Cost of Illness; Cost-Benefit Analysis; Cyclosporine; Dermatology; Drug Administration Schedule; Drug Costs; Female; Health Care Costs; Hospital Costs; Humans; Immunosuppressive Agents; Male; Methotrexate; Netherlands; Outpatient Clinics, Hospital; Psoriasis; Severity of Illness Index; Treatment Outcome | 2004 |
Autoantibody induction in patients with refractory spondyloarthropathy treated with infliximab and methotrexate.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Autoantibodies; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Spondylarthropathies | 2005 |
Low-dose methotrexate pharmacokinetics and pharmacodynamics in the therapy of severe psoriasis.
Topics: Adult; Aged; Area Under Curve; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 2005 |
Folic acid supplementation during treatment of psoriasis with methotrexate: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Dermatologic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Patient Compliance; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2006 |
Methotrexate plus narrowband UVB phototherapy versus narrowband UVB phototherapy alone in the treatment of plaque-type psoriasis: a randomized, placebo-controlled study.
Topics: Adult; Aged; Combined Modality Therapy; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Ultraviolet Therapy | 2006 |
The treatment of psoriasis vulgaris: 1% topical methotrexate gel.
Topics: Administration, Cutaneous; Adolescent; Adult; Dermatologic Agents; Female; Gels; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Single-Blind Method | 2006 |
Approaches to discontinuing efalizumab: an open-label study of therapies for managing inflammatory recurrence.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pilot Projects; Prospective Studies; Psoriasis; Recurrence; Retinoids; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Withholding Treatment | 2006 |
Methotrexate versus hydroxycarbamide (hydroxyurea) as a weekly dose to treat moderate-to-severe chronic plaque psoriasis: a comparative study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Skin; Treatment Outcome | 2007 |
Methotrexate-betamethasone weekly oral pulse in psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Betamethasone; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Severity of Illness Index; Treatment Outcome | 2007 |
The added therapeutic efficacy and safety of alefacept in combination with other (systemic) anti-psoriatics in refractory psoriasis.
Topics: Acitretin; Adult; Aged; Alefacept; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Recombinant Fusion Proteins; Treatment Outcome | 2006 |
Methotrexate vs. ciclosporin in psoriasis: effectiveness, quality of life and safety. A randomized controlled trial.
Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2008 |
A pilot study of pharmacokinetically guided dosing of oral methotrexate in the initial phase of psoriasis treatment.
Topics: Administration, Oral; Adult; Aged; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Erythrocytes; Female; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Psoriasis; Severity of Illness Index; Treatment Outcome | 2008 |
Impact of adalimumab treatment on health-related quality of life and other patient-reported outcomes: results from a 16-week randomized controlled trial in patients with moderate to severe plaque psoriasis.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Dose-Response Relationship, Drug; Epidemiologic Methods; Female; Health Status; Humans; Male; Methotrexate; Psoriasis; Quality of Life; Treatment Outcome | 2008 |
Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION).
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Methotrexate; Psoriasis; Quality of Life; Treatment Outcome | 2008 |
The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis.
Topics: Administration, Oral; Aged; Cross-Over Studies; Dermatologic Agents; Dietary Supplements; Erythrocytes; Female; Folic Acid; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; Patient Compliance; Polyglutamic Acid; Psoriasis; Vitamins | 2008 |
Methotrexate and liver function: a study of 13 psoriasis cases treated with different cumulative dosages.
Topics: Adolescent; Adult; Aged; Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2008 |
Methotrexate in psoriasis with and without leucovorin: effect of different dosage schedules on acute liver toxicity.
Topics: Administration, Oral; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intramuscular; Injections, Intravenous; Leucovorin; Methotrexate; Psoriasis | 1982 |
Reappraisal of the use of methotrexate in rheumatic disease.
Topics: Absorption; Bone Marrow; Clinical Trials as Topic; Drug Interactions; Humans; Liver; Methotrexate; Myositis; Psoriasis; Rheumatic Diseases; Tissue Distribution | 1983 |
Psoriatic arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Clinical Trials as Topic; Humans; Methotrexate; Psoriasis; PUVA Therapy; Vitamin A | 1983 |
Randomized, double-blind, placebo controlled trial of low-dose pulse methotrexate in psoriatic arthritis.
Topics: Adult; Aged; Arthritis; Double-Blind Method; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
[Our experience of psoriatic arthritis and psoriasis treatment with methotrexate (author's transl)].
Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1980 |
Infections during low-dose methotrexate treatment in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Double-Blind Method; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Opportunistic Infections; Prospective Studies; Psoriasis | 1995 |
Methotrexate in psoriatic arthritis.
Topics: Administration, Oral; Adolescent; Adult; Arthritis, Psoriatic; Blood Cells; Dose-Response Relationship, Drug; Humans; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Remission Induction; Retrospective Studies | 1994 |
Bioequivalence of two methotrexate formulations in psoriatic and cancer patients.
Topics: Adult; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drugs, Generic; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Tablets; Therapeutic Equivalency | 1993 |
Serum type III procollagen aminopeptide for assessing liver damage in methotrexate-treated psoriatic patients.
Topics: Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Follow-Up Studies; Humans; Laminin; Liver Diseases; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis; Sensitivity and Specificity | 1996 |
Pharmacokinetics of low doses of methotrexate in patients with psoriasis over the early period of treatment.
Topics: Adult; Aged; Aged, 80 and over; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1998 |
Treatment of psoriatic arthritis with antitumour necrosis factor-alpha antibody clears skin lesions of psoriasis resistant to treatment with methotrexate.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Psoriatic; Dermatologic Agents; Disease Progression; Drug Resistance; Humans; Infliximab; Methotrexate; Psoriasis; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2001 |
A clinical study to determine the efficacy and safety of 1% methotrexate/Azone (MAZ) gel applied topically once daily in patients with psoriasis vulgaris.
Topics: Administration, Cutaneous; Adult; Aged; Dermatologic Agents; Double-Blind Method; Female; Gels; Headache; Humans; Male; Methotrexate; Middle Aged; Pruritus; Psoriasis; Severity of Illness Index; Skin; Treatment Outcome | 2001 |
Treatment of psoriasis with 6-aminonicotinamide.
Topics: Acid-Base Equilibrium; Administration, Oral; Administration, Topical; Adult; Aged; Amines; Biopsy; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Niacinamide; Nicotinic Acids; Psoriasis; Skin; Solvents | 1975 |
Methotrexate uptake by psoriatic epidermis.
Topics: Acid-Base Equilibrium; Clinical Trials as Topic; Humans; Methotrexate; Psoriasis; Skin | 1977 |
Intra-articular methotrexate. Clinical and laboratory study in rheumatoid and psoriatic arthritis.
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Injections, Intra-Articular; Male; Methotrexate; Middle Aged; Psoriasis; Synovial Fluid | 1978 |
Benefits and adverse drug experiences during long-term methotrexate treatment of 248 psoriatics.
Topics: Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1978 |
[Methotrexate in the overall therapy of psoriasis].
Topics: Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Female; Humans; Male; Methotrexate; Psoriasis; Tablets; Time Factors | 1979 |
A prospective study of the effects of weekly oral methotrexate on liver biopsy.
Topics: Administration, Oral; Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1975 |
Azaribine (Triazure) for severe psoriasis.
Topics: Antimetabolites; Azauridine; Child; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Methotrexate; Placebos; Pregnancy; Psoriasis | 1976 |
Epidermal calmodulin levels in psoriasis before & after therapy.
Topics: Adolescent; Adult; Aged; Anthralin; Calmodulin; Drug Administration Schedule; Epidermis; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1991 |
Rationally designed combination chemotherapy for the treatment of patients with recalcitrant psoriasis.
Topics: Adult; Aged; Azauridine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1985 |
Topical treatment of psoriatic skin with methotrexate cream: a clinical, pharmacokinetic, and histological study.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Kinetics; Methotrexate; Middle Aged; Psoriasis; Random Allocation | 1986 |
Pharmacokinetics of small doses of methotrexate in patients with psoriasis.
Topics: Administration, Oral; Adult; Aged; Chronic Disease; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Psoriasis; Random Allocation; Saliva | 1988 |
Topical methotrexate therapy for psoriasis.
Topics: Administration, Topical; Azepines; DNA; Humans; Methotrexate; Pharmaceutical Vehicles; Psoriasis; Random Allocation; Time Factors | 1989 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Gold; Humans; Immunosuppression Therapy; Methotrexate; Pancytopenia; Penicillamine; Placebos; Psoriasis | 1985 |
Historical perspective on the use of methotrexate for the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Aminopterin; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Female; History, 20th Century; Humans; Male; Methotrexate; Pneumonia; Psoriasis; Random Allocation | 1985 |
Toxicity of low dose methotrexate in rheumatoid arthritis.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases | 1985 |
Human low-dosage parenteral methotrexate therapy. A controlled toxicity study.
Topics: Adult; Aged; Clinical Trials as Topic; Dermatitis, Exfoliative; Humans; Injections, Intramuscular; Methotrexate; Middle Aged; Psoriasis | 1966 |
[Therapy of psoriasis using dehydroepiandrosterone-enanthate].
Topics: Administration, Oral; Androstanes; Clinical Trials as Topic; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans; Injections, Intramuscular; Liver; Male; Methotrexate; Pentosephosphates; Psoriasis | 1972 |
A clinical trial of hydroxyurea for psoriasis.
Topics: Adult; Aged; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Immunologic suppression by methotrexate in dermatology.
Topics: Adult; Clinical Trials as Topic; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppression Therapy; Methotrexate; Middle Aged; Neoplasms; Pemphigus; Psoriasis; Skin Diseases; Skin Tests | 1972 |
[Use of methotrexate in psoriasis].
Topics: Clinical Trials as Topic; Drug Evaluation; Humans; Methotrexate; Psoriasis | 1973 |
Hydroxyurea. A new treatment for psoriasis.
Topics: Adult; Aged; Biopsy; Blood Cell Count; Clinical Trials as Topic; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Placebos; Psoriasis | 1970 |
The action of chemotherapeutic agents on psoriatic epidermis.
Topics: Adolescent; Adult; Coal Tar; Dermatologic Agents; Female; Fluocinolone Acetonide; Humans; Male; Methotrexate; Middle Aged; Mitosis; Psoriasis; Skin | 1968 |
1387 other study(ies) available for methotrexate and Palmoplantaris Pustulosis
| Article | Year |
|---|---|
Unusual Cutaneous Reaction at Site of Methotrexate Injection in Two Patients with Psoriasis and Psoriatic Arthritis.
Topics: Arthritis, Psoriatic; Case-Control Studies; Humans; Methotrexate; Psoriasis | 2021 |
Polymorphism in Gene for ABCC2 Transporter Predicts Methotrexate Drug Survival in Patients with Psoriasis.
Topics: Adult; Cohort Studies; Female; Humans; Kaplan-Meier Estimate; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Pharmaceutical Preparations; Psoriasis; Treatment Outcome | 2021 |
Clinical characteristics of Japanese pustular psoriasis: A multicenter observational study.
Topics: Female; Humans; Interleukins; Japan; Male; Methotrexate; Middle Aged; Pregnancy; Psoriasis; Skin Diseases, Vesiculobullous | 2022 |
Treatment satisfaction, safety and effectiveness of adding methotrexate to adalimumab in patients with psoriasis responding suboptimally to adalimumab in a real-world setting.
Topics: Adalimumab; Humans; Methotrexate; Patient Satisfaction; Personal Satisfaction; Psoriasis; Treatment Outcome | 2022 |
Complete recovery of complicated methotrexate-induced liver cirrhosis in a patient with psoriasis: A case report.
Topics: Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 2022 |
Association between different systemic therapies and the risk of tuberculosis in psoriasis patients: A population-based study.
Topics: Adult; Humans; Incidence; Methotrexate; Prospective Studies; Psoriasis; Retrospective Studies; Risk Factors; Tuberculosis | 2021 |
Comparison of noninvasive screening tools for hepatic fibrosis, association with methotrexate cumulative dose, and risk factors in psoriasis patients.
Topics: Adult; Aspartate Aminotransferases; Biomarkers; Case-Control Studies; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors | 2022 |
Management practice, quality of life and associated factors in psoriasis patients attending a dermatological center in Ethiopia.
Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Educational Status; Ethiopia; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Young Adult | 2021 |
Chitosan/hyaluronan nanogels co-delivering methotrexate and 5-aminolevulinic acid: A combined chemo-photodynamic therapy for psoriasis.
Topics: Aminolevulinic Acid; Cell Line; Chitosan; Drug Therapy, Combination; Humans; Hyaluronic Acid; Levulinic Acids; Lipopolysaccharides; Methotrexate; Nanogels; Photosensitizing Agents; Psoriasis | 2022 |
Impact of methotrexate and adalimumab on immune function of patients with psoriasis.
Topics: Adalimumab; Humans; Immunity; Methotrexate; Psoriasis; Treatment Outcome | 2022 |
The difference of lipid profiles between psoriasis with arthritis and psoriasis without arthritis and sex-specific downregulation of methotrexate on the apolipoprotein B/apolipoprotein A-1 ratio.
Topics: Apolipoprotein A-I; Apolipoproteins B; Arthritis, Psoriatic; Down-Regulation; Female; Humans; Lipids; Male; Methotrexate; Prospective Studies; Psoriasis; Sex Factors | 2022 |
Psoriasis rate is increased by the exposure to TNF inhibition in children with JIA.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Child; Humans; Methotrexate; Prospective Studies; Psoriasis; Tumor Necrosis Factor Inhibitors | 2022 |
A pilot study of intralesional methotrexate injections versus triamcinolone acetonide in patients affected by nail matrix psoriasis.
Topics: Humans; Injections, Intralesional; Methotrexate; Nail Diseases; Nails; Nails, Malformed; Pilot Projects; Psoriasis; Quality of Life; Treatment Outcome; Triamcinolone Acetonide | 2022 |
Genetic Markers of Therapeutic Efficacy of Methotrexate in Patients with Psoriasis.
Topics: Genetic Markers; Genotype; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Psoriasis; Thymidylate Synthase | 2022 |
Systemic Methotrexate Treatment in 42 Children with Severe Plaque Psoriasis: A Retrospective Study in China.
Topics: Body Surface Area; Child; Female; Humans; Male; Methotrexate; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2022 |
Microneedle and iontophoresis mediated delivery of methotrexate into and across healthy and psoriatic skin.
Topics: Administration, Cutaneous; Humans; Iontophoresis; Methotrexate; Psoriasis; Skin | 2022 |
Fractional CO2 Laser-Assisted Delivery Versus Intralesional Injection of Methotrexate in Psoriatic Nails.
Topics: Humans; Injections, Intralesional; Lasers, Gas; Methotrexate; Nail Diseases; Nails; Psoriasis | 2022 |
International eDelphi Study to Reach Consensus on the Methotrexate Dosing Regimen in Patients With Psoriasis.
Topics: Adult; Child; Consensus; Folic Acid; Humans; Methotrexate; Psoriasis; Surveys and Questionnaires | 2022 |
Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis.
Topics: Animals; Ceramides; Cholesterol; Disease Models, Animal; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Surface-Active Agents | 2022 |
Anti-IL23for nail psoriasis in real life: Results of efficacy and safety during a 52-week period.
Topics: Acitretin; Humans; Methotrexate; Nail Diseases; Psoriasis; Quality of Life; Treatment Outcome | 2022 |
Combined acitretin-methotrexate therapy seems safe and efficient in children with psoriasis.
Topics: Acitretin; Child; Dermatologic Agents; Drug Therapy, Combination; Humans; Keratolytic Agents; Methotrexate; Psoriasis; Treatment Outcome | 2022 |
Cost per responder of Adalimumab biosimilars MSB11022 and ABP 501 versus the originator and methotrexate in chronic plaque psoriasis.
Topics: Adalimumab; Biosimilar Pharmaceuticals; Humans; Methotrexate; Psoriasis; Treatment Outcome | 2022 |
Sex-differential downregulation of methotrexate on plasma viscosity and whole blood viscosity in psoriasis.
Topics: Blood Viscosity; Cardiovascular Diseases; Down-Regulation; Female; Humans; Male; Methotrexate; Prospective Studies; Psoriasis; Viscosity | 2022 |
Shikonin combined with methotrexate regulate macrophage polarization to treat psoriasis.
Topics: Animals; Imiquimod; Lipopolysaccharides; Macrophages; Methotrexate; Mice; Naphthoquinones; Psoriasis | 2022 |
Monitoring for methotrexate-induced liver fibrosis in many UK dermatology centres is out of date and needs reform.
Topics: Dermatology; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; United Kingdom | 2022 |
Undesirable repigmentation in vitiligo patient receiving methotrexate therapy for the treatment of psoriasis: treatment or side effect?
Topics: Adult; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Melanocytes; Methotrexate; Psoriasis; Vitiligo | 2022 |
Biologic initiation rates in systemic-naive psoriasis patients after first-line apremilast versus methotrexate use.
Topics: Biological Products; Humans; Methotrexate; Psoriasis; Retrospective Studies; Thalidomide | 2022 |
Comment on: 'Monitoring for methotrexate-induced liver fibrosis in many UK dermatology centres is out of date and needs reform'.
Topics: Dermatology; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; United Kingdom | 2022 |
Real-world Methotrexate Use in a Prospective Cohort of Paediatric Patients with Plaque Psoriasis: Effectiveness, Adverse Events and Folic Acid Regimen.
Topics: Adolescent; Child; Female; Folic Acid; Humans; Male; Methotrexate; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome | 2022 |
iTRAQ-based quantitative proteomics reveals biomarkers/pathways in psoriasis that can predict the efficacy of methotrexate.
Topics: Biomarkers; Humans; Janus Kinases; Methotrexate; NF-kappa B; Proteomics; Psoriasis; Signal Transduction; STAT Transcription Factors | 2022 |
Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry).
Topics: Adolescent; Adult; Biological Factors; Biological Products; Child; COVID-19; Disease Progression; Humans; Methotrexate; Pandemics; Psoriasis; Registries | 2022 |
Multiarm study comparing patient-reported and clinical outcome measures in patients undergoing antipsoriatic therapy with non-biological systemic agents in a real-world setting.
Topics: Dermatologic Agents; Humans; Methotrexate; Patient Reported Outcome Measures; Prospective Studies; Psoriasis; Quality of Life; Severity of Illness Index; Treatment Outcome | 2022 |
Predictors of Treatment Change Among Patients with Rheumatoid Arthritis Treated with TNF Inhibitors as First-Line Biologic Agent in the USA: A Cohort Study from Longitudinal Electronic Health Records.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cohort Studies; Electronic Health Records; Female; Glucocorticoids; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Vitamin D | 2022 |
Invasive Aspergillus infection of middle ear in a patient treated with secukinumab, methotrexate, and corticosteroids for psoriasis and psoriatic arthritis.
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Psoriatic; Aspergillosis; Ear, Middle; Humans; Male; Methotrexate; Psoriasis | 2022 |
A case of psoriasis associated with lymphocytic infiltration of Jessner-Kanof successfully treated with methotrexate monotherapy and subsequently with etanercept monotherapy.
Topics: Etanercept; Humans; Leukocyte Disorders; Methotrexate; Psoriasis | 2022 |
A sharp decrease of Th17, CXCR3+-Th17, and Th17.1 in peripheral blood is associated with an early anti-IL-17-mediated clinical remission in psoriasis.
Topics: Biological Products; Cytokines; Humans; Interleukins; Leukocytes, Mononuclear; Methotrexate; Psoriasis; Receptors, CXCR3; Th17 Cells | 2022 |
Understanding Flares in Patients With Generalized Pustular Psoriasis Documented in US Electronic Health Records.
Topics: Acute Disease; Adult; Chronic Disease; Cohort Studies; Cyclosporine; Electronic Health Records; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Skin Diseases, Vesiculobullous; Tacrolimus | 2022 |
Development and evaluation of a novel methotrexate-loaded electrospun patch to alleviate psoriasis plaques.
Topics: Humans; Methotrexate; Polymethacrylic Acids; Psoriasis; Skin Absorption | 2022 |
Oral Squamous Cell Carcinoma Following Acute Methotrexate Toxicity in a Psoriasis Patient: A Causal Association or Mere Co-Incidence.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Incidence; Methotrexate; Middle Aged; Mouth Neoplasms; Psoriasis; Squamous Cell Carcinoma of Head and Neck | 2023 |
Clinical, dermoscopic, and histopathologic evaluation of topical methotrexate 1% hydrogel versus topical Calcipotriol 0.005% cream in the treatment of plaque psoriasis.
Topics: Dermatologic Agents; Emollients; Humans; Hydrogels; Methotrexate; Ointments; Prospective Studies; Psoriasis; Treatment Outcome | 2022 |
Methotrexate toxicity in psoriasis-A multicentric retrospective study.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; India; Leucovorin; Methotrexate; Psoriasis; Retrospective Studies | 2022 |
Risk of malignancy in patients with psoriasis receiving systemic medications: A nested case-control study.
Topics: Adalimumab; Biological Products; Case-Control Studies; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Methotrexate; Neoplasms; Psoriasis; Ustekinumab | 2022 |
Microneedle Patch Delivery of Methotrexate-Loaded Albumin Nanoparticles to Immune Cells Achieves a Potent Antipsoriatic Effect.
Topics: Albumins; Animals; Dermatologic Agents; Drug Delivery Systems; Humans; Methotrexate; Mice; Nanoparticles; Psoriasis | 2022 |
Incidence, Risk Factors, and Consequences of Human Alphaherpesvirus Infections in Patients With Psoriasis Who Initiate Methotrexate or Biologic Agents.
Topics: Adult; Biological Factors; Humans; Immunologic Factors; Incidence; Interleukin-12; Interleukin-17; Male; Methotrexate; Psoriasis; Retrospective Studies; Risk Factors; Tumor Necrosis Factor-alpha | 2022 |
Biologics combined with conventional systemic agents for the treatment of children with severe psoriasis. Real-life data from the BiPe cohorts and a practice survey among French and Italian pediatric dermatologists.
Topics: Acitretin; Adalimumab; Biological Products; Child; Dermatologic Agents; Dermatologists; Etanercept; Humans; Methotrexate; Psoriasis; Treatment Outcome; Tumor Necrosis Factor Inhibitors | 2022 |
Uveitis and nail psoriasis in a patient without articular involvement: a case report.
Topics: Adalimumab; Glaucoma, Open-Angle; Humans; Inflammation; Male; Methotrexate; Psoriasis; Uveitis; Uveitis, Anterior | 2022 |
Association of the characteristics of the blood metabolome and gut microbiome with the outcome of methotrexate therapy in psoriasis.
Topics: Fatty Acids; Gastrointestinal Microbiome; Humans; Lipids; Metabolome; Methotrexate; Prospective Studies; Psoriasis; RNA, Ribosomal, 16S | 2022 |
L36G is associated with cutaneous antiviral competence in psoriasis.
Topics: Antiviral Agents; Computational Biology; Cytokines; Gene Expression Profiling; Humans; Interleukin-1; Interleukins; Methotrexate; Psoriasis | 2022 |
Trends in prescriptions of oral medications for psoriasis: A single-center retrospective study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Etretinate; Humans; Methotrexate; Phosphodiesterase 4 Inhibitors; Psoriasis; Retrospective Studies; Severity of Illness Index | 2023 |
Effects of methotrexate and etanercept treatment in moderate and severe psoriasis.
Topics: Cross-Sectional Studies; Etanercept; Humans; Immunoglobulin G; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Retrospective Studies; Severity of Illness Index | 2022 |
The HLA-Cw*06 allele may predict the response to methotrexate (MTX) treatment in Chinese arthritis-free psoriasis patients.
Topics: Alleles; Arthritis, Psoriatic; East Asian People; Genetic Predisposition to Disease; HLA-C Antigens; Humans; Methotrexate; Psoriasis | 2023 |
Economic Evaluation of Selected Interleukin Inhibitors Versus Methotrexate for Moderate-to-Severe Plaque Psoriasis From the Philippine Payer Perspective.
Topics: Adult; Cost-Benefit Analysis; Humans; Interleukin Inhibitors; Methotrexate; Philippines; Psoriasis | 2023 |
An unusual presentation of acute methotrexate-induced skin toxicity.
Topics: Humans; Methotrexate; Psoriasis; Skin; Skin Diseases | 2023 |
Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Liver Cirrhosis; Longitudinal Studies; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 2023 |
Waning humoral and cellular immunity after COVID-19 vaccination in patients with psoriasis treated with methotrexate and biologics: a cohort study.
Topics: Antibodies, Viral; Biological Products; Cohort Studies; COVID-19; COVID-19 Vaccines; Humans; Immunity, Cellular; Methotrexate; Prospective Studies; Psoriasis; SARS-CoV-2; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Vaccination | 2023 |
No benefit from adding MTX to ustekinumab.
Topics: Humans; Methotrexate; Psoriasis; Treatment Outcome; Ustekinumab | 2023 |
Use of methotrexate and risk of skin cancer: a nationwide case-control study.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Case-Control Studies; Humans; Melanoma, Cutaneous Malignant; Methotrexate; Psoriasis; Risk Factors; Skin Neoplasms | 2023 |
Risk of Infection in Children With Psoriasis Receiving Treatment With Ustekinumab, Etanercept, or Methotrexate Before and After Labeling Expansion.
Topics: Adalimumab; Child; Cohort Studies; Etanercept; Female; Humans; Methotrexate; Psoriasis; Treatment Outcome; Ustekinumab | 2023 |
Conventional therapy in psoriasis. Lost in translation?
Topics: Acitretin; Cohort Studies; Cyclosporine; Fumarates; Humans; Methotrexate; Psoriasis | 2023 |
Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR.
Topics: Acitretin; Adjuvants, Immunologic; Biological Factors; Cohort Studies; Cyclosporine; Dermatologic Agents; Fumarates; Humans; Immunologic Factors; Male; Methotrexate; Prospective Studies; Psoriasis; Treatment Outcome | 2023 |
Topical Delivery of ROS-Responsive Methotrexate Prodrug Nanoassemblies by a Dissolvable Microneedle Patch for Psoriasis Therapy.
Topics: Animals; Imiquimod; Methotrexate; Mice; NF-kappa B; Polyesters; Prodrugs; Psoriasis; Reactive Oxygen Species; Skin | 2023 |
Reactive Oxygen Species-Responsive Gel-Based Microneedle Patches for Prolonged and Intelligent Psoriasis Management.
Topics: Animals; Drug Delivery Systems; Hydrogen Peroxide; Methotrexate; Needles; Psoriasis; Reactive Oxygen Species; Skin | 2023 |
Drug survival of methotrexate and predictor factors for discontinuation in psoriasis.
Topics: Humans; Methotrexate; Psoriasis; Retrospective Studies; Treatment Outcome | 2023 |
COVID-19 vaccination in psoriasis patients receiving systemic treatment: A prospective single-center study.
Topics: Antibodies, Viral; Cohort Studies; COVID-19; COVID-19 Vaccines; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Tumor Necrosis Factor-alpha | 2023 |
The real-world effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for treating moderate-to-severe psoriasis.
Topics: Acitretin; Cohort Studies; Cyclosporine; Fumarates; Humans; Methotrexate; Psoriasis | 2023 |
Immunity 6 months after COVID-19 vaccination in patients with psoriasis treated with immunomodulatory drugs.
Topics: Biological Products; Cohort Studies; COVID-19; COVID-19 Vaccines; Humans; Immunity, Cellular; Immunomodulating Agents; Methotrexate; Psoriasis; Vaccination | 2023 |
Novel Chitosan Nanoparticles Loaded with Methotrexate for Topical Treatment of Psoriasis.
Topics: Animals; Chitosan; Methotrexate; Mice; Nanoparticles; Psoriasis; Rats; Skin | 2023 |
Screening for hepatic fibrosis in patients with psoriasis prescribed methotrexate: can we make a change?
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2023 |
Cost per responder of adalimumab biosimilars versus methotrexate in patients with psoriasis: a real-life experience.
Topics: Adalimumab; Adult; Biosimilar Pharmaceuticals; Humans; Methotrexate; Psoriasis; Treatment Outcome | 2023 |
Immunogenicity, efficacy, and safety of CoronaVac and Pfizer/BioNTech mRNA vaccines in patients with psoriasis receiving systemic therapies: A prospective cohort study.
Topics: Antibodies, Neutralizing; Antibodies, Viral; Biological Factors; COVID-19; COVID-19 Vaccines; Drug-Related Side Effects and Adverse Reactions; Humans; Immunogenicity, Vaccine; Infliximab; Methotrexate; Prospective Studies; Psoriasis; SARS-CoV-2; Vaccines, Inactivated | 2023 |
Incident psoriasis under treatment with tumor necrosis factor-α inhibitors in juvenile idiopathic arthritis patients-analysis of the BiKeR registry.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Etanercept; Humans; Immunologic Factors; Methotrexate; Psoriasis; Registries; Tumor Necrosis Factor-alpha | 2023 |
Psoriasis/Psoriatic Arthritis Patients' Long-term Treatment Patterns and Adherence to Systemic Treatments Monitoring Recommendations.
Topics: Administration, Cutaneous; Arthritis, Psoriatic; Biological Products; Humans; Medication Adherence; Methotrexate; Psoriasis | 2023 |
Should we prefer biologics over nonbiological agents in psoriasis?
Topics: Adalimumab; Adjuvants, Immunologic; Biological Products; Cohort Studies; Dermatologists; Humans; Immunologic Factors; Methotrexate; Psoriasis | 2023 |
Preclinical Demonstration of a Novel Treatment with High Efficacy and No Detectable Toxicity for Inflammatory Skin Conditions including Psoriasis.
Topics: Cell Proliferation; Humans; Keratinocytes; Methotrexate; Psoriasis; Skin; Tumor Necrosis Factor-alpha | 2023 |
Blood-based scoring systems for identifying significant liver fibrosis in patients with psoriasis.
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2023 |
Current issues with procollagen III N-terminal peptide assay performance relevant to 2016 British Association for Dermatologist methotrexate-monitoring guidance.
Topics: Biomarkers; Dermatologists; Humans; Methotrexate; Procollagen; Psoriasis | 2023 |
Comparison of treatment for psoriasis with methotrexate and adalimumab.
Topics: Adalimumab; Humans; Methotrexate; Psoriasis | 2023 |
Does combining adalimumab with methotrexate improve outcomes in psoriasis? Results from 3-year follow-up data.
Topics: Adalimumab; Follow-Up Studies; Humans; Methotrexate; Psoriasis | 2023 |
Psoriasis paradox-infliximab-induced psoriasis in a patient with Crohn's disease: a case report and mini-review.
Topics: Autoimmune Diseases; Crohn Disease; Humans; Infliximab; Methotrexate; Psoriasis | 2023 |
Unlocking the role of the B7-H4 polymorphism in psoriasis: Insights into methotrexate treatment outcomes: A prospective cohort study.
Topics: Genotype; Humans; Methotrexate; Polymorphism, Single Nucleotide; Prospective Studies; Psoriasis; Treatment Outcome | 2024 |
Case Report: Successful treatment with methotrexate in a 10-year-old boy with co-occurrence of generalized psoriasis and vitiligo.
Topics: Biological Products; Child; Humans; Janus Kinase Inhibitors; Male; Methotrexate; Psoriasis; Vitiligo | 2023 |
Decoding clinical and molecular pathways of liver dysfunction in Psoriatic Arthritis: Impact of cumulative methotrexate doses.
Topics: Arthritis, Psoriatic; Cross-Sectional Studies; Humans; Longitudinal Studies; Methotrexate; Non-alcoholic Fatty Liver Disease; Psoriasis; Retrospective Studies | 2023 |
Effectiveness of methotrexate in moderate to severe psoriasis patients: real-world registry data from the Swiss Dermatology Network for Targeted Therapies (SDNTT).
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid Antagonists; Humans; Injections, Subcutaneous; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Molecular Targeted Therapy; Multicenter Studies as Topic; Nausea; Prospective Studies; Psoriasis; Randomized Controlled Trials as Topic; Registries; Remission Induction; Severity of Illness Index; Switzerland; Treatment Outcome; Young Adult | 2019 |
Development, characterization and evaluation of topical methotrexate-entrapped deformable liposome on imiquimod-induced psoriasis in a mouse model.
Topics: Administration, Cutaneous; Animals; Disease Models, Animal; Female; Folic Acid Antagonists; Imiquimod; Immunosuppressive Agents; Liposomes; Methotrexate; Mice, Inbred BALB C; Psoriasis | 2019 |
Apremilast does not appear to outlast methotrexate.
Topics: Humans; Methotrexate; National Health Programs; Psoriasis; Thalidomide | 2020 |
Development of Topical Gel of Methotrexate Incorporated Ethosomes and Salicylic Acid for the Treatment of Psoriasis.
Topics: Acrylates; Administration, Cutaneous; Animals; Antipsychotic Agents; Disease Models, Animal; Drug Compounding; Drug Liberation; Gels; Guinea Pigs; Humans; Lecithins; Liposomes; Methotrexate; Mice; Parakeratosis; Permeability; Psoriasis; Salicylic Acid; Skin; Skin Absorption | 2019 |
Changes in serum TNF-like weak inducer of apoptosis (TWEAK) levels and Psoriasis Area Severity Index (PASI) scores in plaque psoriasis patients treated with conventional versus anti-TNF treatments.
Topics: Acitretin; Adalimumab; Adult; Anti-Inflammatory Agents; Cyclosporine; Cytokine TWEAK; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2020 |
Real-world comparative effectiveness of adalimumab, etanercept and methotrexate: a Swedish register analysis.
Topics: Adalimumab; Adult; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Registries; Sweden; Treatment Outcome | 2020 |
Non-Melanoma Skin Cancer Risk Among Patients in the Psoriasis Longitudinal Assessment and Registry (PSOLAR)
Topics: Biological Products; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatologic Agents; Humans; Longitudinal Studies; Methotrexate; Psoriasis; Registries; Risk Assessment; Risk Factors; Skin Neoplasms | 2019 |
Risk of major cardiovascular events in patients with psoriasis receiving biologic therapies: a prospective cohort study.
Topics: Adalimumab; Adult; Biological Therapy; Etanercept; Female; Heart Disease Risk Factors; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Ustekinumab | 2020 |
[Lower risk of severe infections in psoriasis with certain biologics versus methotrexate].
Topics: Biological Products; Humans; Infections; Methotrexate; Psoriasis; Ustekinumab | 2019 |
Nail psoriasis treated with intralesional methotrexate infiltration.
Topics: Female; Humans; Injections, Intralesional; Male; Methotrexate; Middle Aged; Nail Diseases; Nucleic Acid Synthesis Inhibitors; Psoriasis; Reproducibility of Results; Time Factors; Treatment Outcome | 2019 |
Hyaluronic Acid-Based Dissolving Microneedle Patch Loaded with Methotrexate for Improved Treatment of Psoriasis.
Topics: Animals; Disease Models, Animal; Drug Delivery Systems; Female; Humans; Hyaluronic Acid; Methotrexate; Mice; Mice, Inbred BALB C; Needles; Psoriasis | 2019 |
Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Gold; Humans; Imiquimod; Immunity; Methotrexate; Mice; Mice, Inbred C57BL; Nanoparticles; Psoriasis; Skin; Th17 Cells; Xenograft Model Antitumor Assays | 2020 |
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients.
Topics: Adolescent; Adrenal Cortex Hormones; Anthralin; Biological Products; Calcineurin Inhibitors; Cardiovascular Diseases; Child; Child, Preschool; Coal Tar; Comorbidity; Cyclosporine; Dermatologic Agents; Dyslipidemias; Evidence-Based Medicine; Humans; Infant; Infant, Newborn; Inflammatory Bowel Diseases; Insulin Resistance; Mental Health; Metabolic Syndrome; Methotrexate; Nicotinic Acids; Obesity; Photochemotherapy; Psoriasis; Retinoids | 2020 |
Pemphigus vulgaris with psoriasis vulgaris successfully treated with methotrexate and low-dose methylprednisolone.
Topics: Aged; Dermatologic Agents; Drug Therapy, Combination; Humans; Male; Methotrexate; Methylprednisolone; Pemphigus; Psoriasis; Treatment Outcome | 2020 |
The utility of subcutaneous methotrexate for chronic plaque psoriasis in a real-world setting.
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2020 |
Characteristics and Management of Autoimmune Bullous Disease in Psoriasis Patients.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Cyclosporine; Disease Management; Enzyme Inhibitors; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Pemphigoid, Bullous; Pemphigus; Psoriasis; Retrospective Studies; Ultraviolet Therapy | 2019 |
Synthesis and in vitro cytotoxicity evaluation of star-shaped polymethacrylic conjugates with methotrexate or acitretin as potential antipsoriatic prodrugs.
Topics: Acitretin; Apoptosis; Cell Cycle; Cell Line, Tumor; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Humans; Methotrexate; Polymethacrylic Acids; Psoriasis; Skin | 2020 |
Dihydrochalcone Derivatives from
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Antioxidants; Chalcones; Dermatologic Agents; Epidermis; Female; Humans; Inhibitory Concentration 50; Ki-67 Antigen; Male; Membrane Proteins; Methotrexate; Middle Aged; Populus; Protein Precursors; Psoriasis; Quality of Life; Skin; Tissue Engineering; Young Adult | 2019 |
A Long-Term Follow-up of Retinal Vasculitis - Do They Develop Systemic Disease?
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Azathioprine; Colitis, Ulcerative; Cyclosporine; Drug Therapy, Combination; Female; Fluorescein Angiography; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Retinal Vasculitis; Retrospective Studies; Tuberculin Test; Tuberculosis, Ocular; Visual Acuity; Vitreous Hemorrhage | 2020 |
Amelanotic Melanoma Concealed by Psoriasis.
Topics: Adult; Dermatologic Agents; Dermoscopy; Female; Humans; Melanoma, Amelanotic; Methotrexate; Psoriasis; Skin Neoplasms | 2020 |
Verrucous psoriasis treated with methotrexate and acitretin combination therapy.
Topics: Acitretin; Aged; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Keratolytic Agents; Methotrexate; Psoriasis | 2019 |
Methotrexate treatment for patients with psoriasis and risk of cutaneous melanoma: a nested case-control study.
Topics: Australia; Case-Control Studies; Humans; Melanoma; Methotrexate; Psoriasis; Retrospective Studies; Skin Neoplasms; Sweden | 2020 |
A Comparison of Psoriasis Severity in Pediatric Patients Treated With Methotrexate vs Biologic Agents.
Topics: Adolescent; Biological Factors; Child; Cohort Studies; Etanercept; Female; Humans; Male; Methotrexate; Psoriasis; Retrospective Studies; Severity of Illness Index; Survival Rate | 2020 |
United States systemic psoriasis treatments: increases in the use of biologic agents and plateau of methotrexate and oral small molecule inhibitors.
Topics: Biological Factors; Health Care Surveys; Humans; Immunotherapy; Methotrexate; Psoriasis; United States | 2022 |
Switching from pemphigus vulgaris to psoriasis: a rare report of three cases.
Topics: Adult; Autoantibodies; Biopsy; Desmoglein 1; Desmoglein 3; Humans; Male; Methotrexate; Pemphigus; Psoriasis; Skin; Treatment Outcome | 2020 |
Adverse event monitoring in patients on oral systemic medications for inflammatory skin disease.
Topics: Azathioprine; Cross-Sectional Studies; Cyclosporine; Dermatitis, Atopic; Drug Eruptions; Drug Monitoring; Humans; Methotrexate; Mycophenolic Acid; Psoriasis; United States | 2020 |
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies.
Topics: Acitretin; Cyclosporine; Drug Monitoring; Humans; Methotrexate; Piperidines; Psoriasis; Pyrimidines; Thalidomide | 2020 |
[Management of plaque psoriasis in adults].
Topics: Administration, Oral; Administration, Topical; Adult; Arthritis, Psoriatic; Biological Therapy; Dermatologic Agents; Germany; Humans; Methotrexate; Molecular Targeted Therapy; Phosphodiesterase 4 Inhibitors; Phototherapy; Psoriasis; Severity of Illness Index; Treatment Outcome | 2020 |
Do we need to fear methotrexate?
Topics: Case-Control Studies; Fear; Humans; Melanoma; Methotrexate; Psoriasis; Skin Neoplasms | 2020 |
A Red, Painful, and Swollen Foot Overlying a Bone Erosion.
Topics: Aged; Antirheumatic Agents; Arthritis, Psoriatic; Bone Marrow; Diagnosis, Differential; Edema; Enthesopathy; Erythema; Finger Joint; HLA-B27 Antigen; Humans; Infliximab; Male; Methotrexate; Osteomyelitis; Pain; Physical Examination; Psoriasis; Synovitis; Toe Joint; Toe Phalanges | 2020 |
Fumaric acid esters for the treatment of psoriasis in Germany: characterising patients in routine care.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Comorbidity; Dermatologic Agents; Female; Fumarates; Germany; Humans; Hypertension; Male; Methotrexate; Middle Aged; Prevalence; Psoriasis; Quality of Life; Registries; Severity of Illness Index; Time Factors; Young Adult | 2020 |
The impacts of gene polymorphisms on methotrexate in Chinese psoriatic patients.
Topics: Adult; Aged; Arthritis, Psoriatic; Asian People; China; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Young Adult | 2020 |
Effect of narrow-band ultraviolet B phototherapy, methotrexate, and combined narrow-band ultraviolet B phototherapy with methotrexate on serum cathelicidin and vitamin D in patients with psoriasis vulgaris.
Topics: Antimicrobial Cationic Peptides; Cathelicidins; Humans; Methotrexate; Phototherapy; Psoriasis; Ultraviolet Therapy; Vitamin D | 2022 |
Psoriatic Dactylitis.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Fingers; Hand Dermatoses; Humans; Keratosis; Male; Methotrexate; Middle Aged; Psoriasis; Radiography; Treatment Outcome | 2020 |
Prologue: 2019 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Diagnostic Tests, Routine; Enthesopathy; Humans; Methotrexate; Outcome Assessment, Health Care; Precision Medicine; Psoriasis; Training Support | 2020 |
Methotrexate in Psoriasis and Psoriatic Arthritis.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Humans; Methotrexate; Psoriasis | 2020 |
Localised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis.
Topics: Administration, Cutaneous; Animals; Drug Delivery Systems; Methotrexate; Nanoparticles; Needles; Psoriasis; Rats; Rats, Sprague-Dawley; Skin | 2020 |
Psoriasis, transient elastography and methotrexate: monitoring at a tertiary hospital.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Tertiary Care Centers | 2021 |
Methotrexate-Loaded Nanostructured Lipid Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation, Optimization, Characterization, In-Vitro and In-Vivo Studies.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Catalase; Cytokines; Drug Carriers; Drug Compounding; Drug Liberation; Gels; Glutathione; Humans; Imiquimod; Inflammation; Lipids; Malondialdehyde; Methotrexate; Mice, Inbred BALB C; Nanostructures; Organ Size; Psoriasis; Superoxide Dismutase | 2020 |
Adalimumab and methotrexate affect the concentrations of regulatory cytokines (interleukin-10, transforming growth factor-β1, and interleukin-35) in patients with plaque psoriasis.
Topics: Adalimumab; Cytokines; Humans; Interleukin-10; Methotrexate; Psoriasis; Severity of Illness Index; Transforming Growth Factor beta1; Treatment Outcome | 2020 |
Reduced risk of mortality associated with systemic psoriasis treatment in the Psoriasis Longitudinal Assessment and Registry (PSOLAR): A nested case-control analysis.
Topics: Aged; Case-Control Studies; Cause of Death; Dermatologic Agents; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Registries; Tumor Necrosis Factor-alpha; Ustekinumab | 2021 |
Association of the Psoriatic Microenvironment With Treatment Response.
Topics: Adalimumab; Biological Factors; Biopsy; Clinical Decision-Making; Datasets as Topic; Etanercept; Gene Expression Profiling; Humans; Methotrexate; Piperidines; Precision Medicine; Prognosis; Psoriasis; Pyrimidines; Retrospective Studies; RNA, Messenger; Severity of Illness Index; Skin; Transcriptome; Treatment Outcome; Whole Genome Sequencing | 2020 |
Treatment modalities and risk of adverse events associated with biologic therapy: A 10-year observational review of the Australasian Psoriasis Registry.
Topics: Adalimumab; Australia; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; New Zealand; Phototherapy; Psoriasis; Registries; Retrospective Studies; Ustekinumab | 2021 |
Enhanced Inflammasome Activity in Patients with Psoriasis Promotes Systemic Inflammation.
Topics: Adult; Aged; Aged, 80 and over; Animals; Case-Control Studies; Caspase 1; Female; Healthy Volunteers; Humans; Inflammasomes; Inflammation; Interleukin-18; Interleukin-1beta; Male; Methotrexate; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis; Severity of Illness Index; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha | 2021 |
Unmet needs in patients with moderate-to-severe plaque psoriasis treated with methotrexate in real world practice: FirST study.
Topics: Cross-Sectional Studies; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Quality of Life; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2022 |
Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8
Topics: Animals; Artemisinins; CD8-Positive T-Lymphocytes; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Imiquimod; Immunologic Memory; Interleukin-15; Interleukin-17; Male; Methotrexate; Mice; Psoriasis; Recurrence; Secondary Prevention; Skin; Skin Transplantation; Transplantation Chimera | 2020 |
Efficacy and safety of ixekizumab after switching from fumaric acid esters or methotrexate in patients with moderate-to-severe plaque psoriasis naïve to systemic treatment.
Topics: Antibodies, Monoclonal, Humanized; Dermatologic Agents; Fumarates; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2021 |
Utilizing Fibrosis-4 score to assess risk for hepatic fibrosis in patients with psoriasis on methotrexate.
Topics: Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 2021 |
Severe Pancytopenia Following Single Dose Methotrexate In Psoriasis: A Rare And Potentially Lethal Manifestation.
Topics: Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis | 2021 |
Treating multidrug-resistant psoriasis with brodalumab, apremilast, methotrexate and prednisone combination therapy in the COVID-19 pandemic.
Topics: Adult; Antibodies, Monoclonal, Humanized; COVID-19; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Methotrexate; Prednisone; Psoriasis; SARS-CoV-2; Thalidomide | 2020 |
Correspondence on 'Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and Mendelian randomisation study'.
Topics: Arthritis, Psoriatic; Humans; Methotrexate; Osteoporosis; Psoriasis | 2023 |
Rupioid psoriasis on the hands.
Topics: Adult; Antimanic Agents; Dermatologic Agents; Hand; Humans; Male; Methotrexate; Psoriasis; Valproic Acid | 2020 |
The value of subcutaneous vs. oral methotrexate: real-world data from the German psoriasis registry PsoBest.
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis; Registries; Treatment Outcome | 2021 |
Planifier une grossesse chez une patiente avec un psoriasis.
Topics: Acitretin; Contraindications, Drug; Dermatologic Agents; Female; Fertility; Humans; Male; Methotrexate; Patient Care Planning; Preconception Care; Pregnancy; Pregnancy Complications; Psoriasis | 2020 |
Le choix thérapeutique : médicaments du psoriasis et grossesse avant, pendant et après la grossesse.
Topics: Acitretin; Biological Factors; Breast Feeding; Contraindications, Drug; Cyclosporine; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Psoriasis; Risk Factors; Ultraviolet Therapy | 2020 |
Immune checkpoint-mediated psoriasis: A multicenter European study of 115 patients from the European Network for Cutaneous Adverse Event to Oncologic Drugs (ENCADO) group.
Topics: Acitretin; Aged; Biological Products; Dermatologic Agents; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; Glucocorticoids; Humans; Immune Checkpoint Inhibitors; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Retrospective Studies; Severity of Illness Index; Thalidomide; Treatment Outcome | 2021 |
Analysis of key markers: IL-10/sHLA-G in psoriasis patients and the identification of 14-bp INDEL in the HLA-G gene.
Topics: Case-Control Studies; Genes, MHC Class I; HLA-G Antigens; Humans; INDEL Mutation; Interleukin-10; Methotrexate; Polymorphism, Genetic; Psoriasis | 2022 |
Methotrexate Use for Patients with Psoriasis and Risk of Cutaneous Squamous Cell Carcinoma: A Nested Case-control Study.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Humans; Methotrexate; Psoriasis; Skin Neoplasms; Sweden | 2021 |
Psoriasis in Tigray, Ethiopia: Focusing on available treatments.
Topics: Arthritis, Psoriatic; Ethiopia; Humans; Methotrexate; Psoriasis; Retrospective Studies | 2022 |
The Effect of Methotrexate on Serum Levels of Trace/Mineral Elements in Patients with Psoriatic Arthritis.
Topics: Arthritis, Psoriatic; Humans; Methotrexate; Minerals; Psoriasis; Trace Elements | 2021 |
Developmental cell programs are co-opted in inflammatory skin disease.
Topics: Animals; Atlases as Topic; Cell Movement; Datasets as Topic; Dendritic Cells; Dermatitis, Atopic; Dermatologic Agents; Humans; Immunity, Innate; Methotrexate; Mice; Phagocytes; Psoriasis; Single-Cell Analysis; Skin; T-Lymphocytes; Transcriptome | 2021 |
First-Line Biologic Therapy and Obesity in Moderate-to-Severe Psoriasis: Results from the Prospective Multicenter Cohort Psobioteq.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Biological Therapy; Body Mass Index; Cohort Studies; Dermatologic Agents; Etanercept; Female; France; Humans; Infliximab; Male; Methotrexate; Middle Aged; Obesity; Patient Selection; Psoriasis; Ustekinumab | 2021 |
The Impact of ANxA6 Gene Polymorphism on the Efficacy of Methotrexate Treatment in Psoriasis Patients.
Topics: Adult; Aged; Annexin A6; Dermatologic Agents; Female; Genotype; Humans; Male; Methotrexate; Middle Aged; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Psoriasis; Severity of Illness Index | 2021 |
Risk of liver disease in patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis receiving methotrexate: A population-based study.
Topics: Adult; Aged; Arthritis, Psoriatic; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Denmark; Female; Follow-Up Studies; Humans; Incidence; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Assessment; Risk Factors; Severity of Illness Index | 2021 |
Topics: Female; Hand; Humans; Methotrexate; Middle Aged; Psoriasis | 2021 |
Polymorphisms in GNMT and DNMT3b are associated with methotrexate treatment outcome in plaque psoriasis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatologic Agents; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Female; Glycine N-Methyltransferase; Humans; Infant; Infant, Newborn; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Protein 2; Pharmacogenomic Testing; Polymorphism, Single Nucleotide; Psoriasis; Registries; Retrospective Studies; Treatment Outcome; Young Adult | 2021 |
A case of idiopathic membranous nephropathy and psoriasis vulgaris.
Topics: Cyclophosphamide; Dermatologic Agents; Diagnosis, Differential; Drug Therapy, Combination; Etanercept; Glomerulonephritis, Membranous; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prednisolone; Psoriasis | 2022 |
Hyperlipidaemia in psoriatic disease: higher prevalence in psoriatic arthritis and inverse association with systemic therapy.
Topics: Adult; Age Factors; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Biological Products; Comorbidity; Female; Glucocorticoids; Humans; Hyperlipidemias; Male; Methotrexate; Middle Aged; Odds Ratio; Protective Factors; Psoriasis; Risk Factors | 2021 |
The potential impact of systemic anti-inflammatory therapies in psoriasis on major adverse cardiovascular events: a Korean nationwide cohort study.
Topics: Acitretin; Adult; Aged; Anti-Inflammatory Agents; Cardiovascular Diseases; Cyclosporine; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Phototherapy; Proportional Hazards Models; Psoriasis; Republic of Korea; Severity of Illness Index; Young Adult | 2021 |
Erosions of Psoriatic Plaques Due to Methotrexate.
Topics: Humans; Methotrexate; Psoriasis; Skin Ulcer | 2021 |
This Month in JAAD: June 2021.
Topics: Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury; Dermoscopy; Humans; Melanoma; Methotrexate; Phototherapy; Psoriasis; Risk Assessment; Risk Factors; Skin; Skin Neoplasms; Skin Pigmentation; Vitiligo | 2021 |
Psoriasis: a brief overview.
Topics: Acitretin; Humans; Immunosuppressive Agents; Methotrexate; Phototherapy; Psoriasis | 2021 |
Drug survival and predictor factors for discontinuation of methotrexate in psoriasis: a real-life multicenter study.
Topics: Humans; Methotrexate; Middle Aged; Multivariate Analysis; Pharmaceutical Preparations; Psoriasis; Treatment Outcome | 2021 |
Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization and Mortality in Patients with Psoriasis: A Population-Based Study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biological Products; Case-Control Studies; Child; Child, Preschool; Comorbidity; COVID-19; Female; Hospitalization; Humans; Immunosuppressive Agents; Infant; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors; SARS-CoV-2; Young Adult | 2021 |
Incidence and Risk Factors of Hepatic Fibrosis in Psoriatic Patients Receiving Methotrexate with Concomitant Acitretin Therapy and Methotrexate Monotherapy.
Topics: Acitretin; Cohort Studies; Drug Therapy, Combination; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Retrospective Studies; Risk Factors | 2021 |
Co-delivery of methotrexate and nicotinamide by cerosomes for topical psoriasis treatment with enhanced efficacy.
Topics: Administration, Topical; Animals; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Niacinamide; Psoriasis; Skin | 2021 |
A case of psoriasis successfully treated by extracorporeal photopheresis during COVID-19 pandemic.
Topics: Acitretin; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Contraindications, Drug; COVID-19; Cyclosporine; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Nails; Pandemics; Photopheresis; Psoriasis; Quality of Life; SARS-CoV-2; Severity of Illness Index; Ultraviolet Therapy | 2021 |
Psoriasis treatment patterns and outcomes with ixekizumab in a real-world setting: results from a single US dermatology referral practice.
Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Biological Products; Dermatology; Humans; Methotrexate; Psoriasis; Referral and Consultation; Retrospective Studies; Treatment Outcome | 2022 |
Development, characterization and optimization of methotrexate-olive oil nano-emulsion for topical application.
Topics: Administration, Cutaneous; Animals; Dermatologic Agents; Drug Carriers; Emulsions; Methotrexate; Nanoparticle Drug Delivery System; Olive Oil; Psoriasis; Rabbits; Skin; Skin Absorption | 2021 |
Treating the skin with biologics in patients with psoriasis decreases the incidence of psoriatic arthritis.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Argentina; Arthritis, Psoriatic; Biological Products; Body Mass Index; Cyclosporine; Electronic Health Records; Etanercept; Female; Humans; Incidence; Infliximab; Male; Methotrexate; Middle Aged; Nail Diseases; Phototherapy; Psoriasis; Retrospective Studies; Risk Factors; Sex Factors; Ustekinumab; Young Adult | 2022 |
A Genome-wide association study identified HLA-C associated with the effectiveness of methotrexate for psoriasis treatment.
Topics: Genetic Predisposition to Disease; Genome-Wide Association Study; HLA-C Antigens; Humans; Methotrexate; Psoriasis | 2021 |
Methotrexate use and liver outcomes in psoriasis and rheumatoid arthritis patients: A commentary on "Risk of liver disease in patients with psoriasis, psoriatic arthritis and rheumatoid arthritis receiving methotrexate: A population-based study".
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Humans; Liver Diseases; Methotrexate; Psoriasis | 2021 |
Response to: "Methotrexate Use and Liver Outcomes in Psoriasis and Rheumatoid Arthritis Patients: A Commentary on 'Risk of liver disease in patients with psoriasis, psoriatic arthritis and rheumatoid arthritis receiving methotrexate: A population-based st
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Humans; Liver Diseases; Methotrexate; Psoriasis | 2021 |
Effect of systemic methotrexate on lipid pentad index in psoriasis and its association with disease severity.
Topics: Apolipoprotein A-I; Apolipoprotein B-100; Female; Humans; Immunosuppressive Agents; India; Lipoprotein(a); Male; Methotrexate; Psoriasis; Severity of Illness Index | 2017 |
Management of patients with psoriasis.
Topics: Acitretin; Administration, Cutaneous; Anti-Inflammatory Agents; Betamethasone; Calcitriol; Cyclosporine; Dermatologic Agents; Disease Management; Emollients; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Phototherapy; Psoriasis; Thalidomide | 2017 |
The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis.
Topics: Acitretin; Animals; Cells, Cultured; Dermatologic Agents; Drug Therapy, Combination; Humans; Keratolytic Agents; Liver; Liver Cirrhosis; Male; Methotrexate; Mice; Psoriasis; Skin | 2017 |
Transient Elastography May Improve Detection of Liver Fibrosis in Psoriasis Patients Treated with Methotrexate.
Topics: Biomarkers; Case-Control Studies; Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Psoriasis; Time Factors; Treatment Outcome | 2017 |
Folic acid - Who does what with methotrexate?
Topics: Drug Therapy, Combination; Folic Acid; Humans; Methotrexate; Practice Patterns, Physicians'; Psoriasis | 2017 |
Pharmacogenetic markers to predict the clinical response to methotrexate in south Indian Tamil patients with psoriasis.
Topics: Adult; Biomarkers; Cornified Envelope Proline-Rich Proteins; Cytokines; Female; Forkhead Transcription Factors; Genotype; HLA-A2 Antigen; HLA-B Antigens; HLA-C Antigens; Humans; Immunosuppressive Agents; India; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; White People | 2017 |
Real world prescription trends of methotrexate for psoriasis in Argentina: results of a national survey.
Topics: Argentina; Cross-Sectional Studies; Drug Administration Routes; Drug Administration Schedule; Humans; Methotrexate; Odds Ratio; Psoriasis; Surveys and Questionnaires; Treatment Outcome | 2017 |
Recovery of hair in the psoriatic plaques of a patient with coexistent alopecia universalis.
Topics: Adult; Alopecia; Dermatologic Agents; Diagnosis, Differential; Etanercept; Hair; Humans; Male; Methotrexate; Psoriasis | 2017 |
HLA-Cw6-positive patients with psoriasis show improved response to methotrexate treatment.
Topics: Adolescent; Adult; Aged; Cohort Studies; Female; Genotype; HLA-C Antigens; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pharmacogenomic Testing; Phenotype; Psoriasis; Treatment Outcome; Young Adult | 2017 |
Palmoplantar pustulosis - a cross-sectional analysis in Germany.
Topics: Acitretin; Adrenal Cortex Hormones; Adult; Age of Onset; Arthritis, Psoriatic; Body Mass Index; Comorbidity; Cross-Sectional Studies; Dermatologic Agents; Female; Germany; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Severity of Illness Index; Smoking; Ultraviolet Therapy; Young Adult | 2017 |
The METOP Study: Further Evidence for the Use of Subcutaneous Methotrexate in Psoriasis.
Topics: Dermatologic Agents; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic | 2017 |
Quality of life, treatment satisfaction and efficacy of non-biological systemic therapies in patients with plaque psoriasis: study protocol for a prospective observational study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dermatologic Agents; Fumarates; Humans; Methotrexate; Patient Compliance; Patient Satisfaction; Personal Satisfaction; Pilot Projects; Prospective Studies; Psoriasis; Quality of Life; Thalidomide | 2017 |
Widespread psoriasis flare following influenza vaccination.
Topics: Adrenal Cortex Hormones; Adult; Humans; Immunosuppressive Agents; Influenza Vaccines; Male; Methotrexate; Psoriasis; Treatment Outcome; Vaccination; Vaccines, Inactivated | 2017 |
[Osteopecilia associated with psoriatic arthritis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Female; Humans; Leg Length Inequality; Methotrexate; Osteopoikilosis; Psoriasis; Sacroiliitis; Tomography, X-Ray Computed | 2017 |
Medication adherence among patients with psoriasis on traditional systemic and biologics treatment.
Topics: Adalimumab; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biological Products; Dermatologic Agents; Etanercept; Female; Fumarates; Humans; Male; Medication Adherence; Methotrexate; Middle Aged; Psoriasis; Sex Factors; Ustekinumab; Young Adult | 2018 |
Topical co-delivery of methotrexate and etanercept using lipid nanoparticles: A targeted approach for psoriasis management.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Cell Line; Etanercept; Fibroblasts; Humans; Keratinocytes; Lipids; Methotrexate; Nanoparticles; Psoriasis; Skin; Skin Absorption; Swine | 2017 |
Toxoplasma Appendicitis: A Once-in-a-Lifetime Diagnosis!
Topics: Appendicitis; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Toxoplasmosis | 2018 |
Drug survival of methotrexate in psoriasis.
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis | 2017 |
Methotrexate, but not narrowband ultraviolet B radiation, suppresses interleukin-33 mRNA levels in psoriatic plaques and protein levels in serum of patients with psoriasis.
Topics: Adult; Aged; Cell Nucleus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-33; Keratinocytes; Male; Methotrexate; Middle Aged; Psoriasis; RNA, Messenger; Skin; Ultraviolet Therapy; Up-Regulation; Young Adult | 2018 |
Risk of malignancy with systemic psoriasis treatment in the Psoriasis Longitudinal Assessment Registry.
Topics: Adult; Age Distribution; Aged; Biological Products; Case-Control Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Incidence; Logistic Models; Longitudinal Studies; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasms; Prognosis; Psoriasis; Registries; Risk Assessment; Severity of Illness Index; Sex Distribution; Tumor Necrosis Factor-alpha; Ustekinumab | 2017 |
Clinical challenges faced in real-world management of moderate-to-severe psoriasis: a personal view.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Psoriatic; Biological Products; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Disease Management; Humans; Lymphoma, Non-Hodgkin; Mental Disorders; Methotrexate; Photochemotherapy; Psoriasis | 2017 |
Biologics combined with conventional systemic agents or phototherapy for the treatment of psoriasis: real-life data from PSONET registries.
Topics: Acitretin; Adalimumab; Austria; Biological Products; Combined Modality Therapy; Cyclosporine; Czech Republic; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Fumarates; Humans; Infliximab; Israel; Italy; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Netherlands; Psoriasis; PUVA Therapy; Registries; Severity of Illness Index; Ustekinumab | 2018 |
Safety of Systemic Agents for the Treatment of Pediatric Psoriasis.
Topics: Adolescent; Child; Child, Preschool; Dermatologic Agents; Europe; Female; Folic Acid; Humans; Immunosuppressive Agents; Male; Methotrexate; North America; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Medication nonadherence in dermatology: Divergent ethical implications for patient care.
Topics: Administration, Topical; Adrenal Cortex Hormones; Dermatology; Drug Administration Schedule; Drug Therapy, Combination; Folic Acid; Humans; Male; Medication Adherence; Methotrexate; Middle Aged; Monitoring, Physiologic; Physician-Patient Relations; Psoriasis; Risk Assessment; Severity of Illness Index; Treatment Failure | 2017 |
[Apparent worsening of psoriasis lesions revealing methotrexate overdosage].
Topics: Dermatologic Agents; Drug Eruptions; Drug Overdose; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 2018 |
A Case of Inappropriate Self-Medication Compounded with Prescribing
Topics: Dermatologic Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Medication Errors; Methotrexate; Middle Aged; Psoriasis; Self Medication | 2018 |
Effect of ablative laser on in vitro transungual delivery.
Topics: Administration, Topical; Animals; Cattle; Dermatologic Agents; Drug Delivery Systems; Hoof and Claw; Humans; Laser Therapy; Methotrexate; Microscopy, Confocal; Models, Animal; Nail Diseases; Permeability; Psoriasis | 2018 |
Anti-psoriatic and toxicity evaluation of methotrexate loaded chitin nanogel in imiquimod induced mice model.
Topics: Aminoquinolines; Animals; Chitin; Disease Models, Animal; Drug Delivery Systems; Humans; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; THP-1 Cells | 2018 |
Methotrexate Management in Psoriasis: Are We Following the Guidelines?
Topics: Dermatologists; Dermatology; Female; Guideline Adherence; Hospitals, University; Humans; Immunosuppressive Agents; Longitudinal Studies; Male; Methotrexate; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Psoriasis; Retrospective Studies; Sweden; Time Factors; Treatment Outcome | 2018 |
Advancing paediatric psoriasis treatment options for children.
Topics: Adalimumab; Adolescent; Child; Double-Blind Method; Humans; Methotrexate; Psoriasis; Severity of Illness Index | 2017 |
Localized inflammatory reactions at sites of subcutaneous methotrexate injections during treatment with ultraviolet B.
Topics: Biopsy; Combined Modality Therapy; Female; Humans; Immunosuppressive Agents; Injection Site Reaction; Injections, Subcutaneous; Male; Methotrexate; Psoriasis; Skin; Ultraviolet Therapy | 2018 |
In vivo anti-psoriatic activity, biodistribution, sub-acute and sub-chronic toxicity studies of orally administered methotrexate loaded chitin nanogel in comparison with methotrexate tablet.
Topics: Administration, Oral; Animals; Chitin; Gels; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; Tablets | 2018 |
Subcutaneous methotrexate in patients with moderate-to-severe psoriasis: a critical appraisal.
Topics: Adult; Double-Blind Method; France; Germany; Humans; Male; Methotrexate; Middle Aged; Netherlands; Prospective Studies; Psoriasis; Treatment Outcome | 2018 |
Studying the effect of systemic and biological drugs on intima-media thickness in patients suffering from moderate and severe psoriasis.
Topics: Adult; Biological Products; Blood Glucose; Carotid Intima-Media Thickness; Dermatologic Agents; Female; Humans; Insulin; Lipoproteins, LDL; Longitudinal Studies; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Severity of Illness Index; Tumor Necrosis Factor-alpha; Tunica Intima; Tunica Media; Ustekinumab | 2018 |
Does daily folic acid supplementation reduce methotrexate efficacy?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biological Availability; Dermatologic Agents; Drug Antagonism; Folic Acid; Humans; Methotrexate; Psoriasis | 2017 |
The clock is ticking.
Topics: Cardiovascular Diseases; Comorbidity; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Risk Factors; Tumor Necrosis Factor-alpha | 2018 |
Methotrexate restores the function of peripheral blood regulatory T cells in psoriasis vulgaris via the CD73/AMPK/mTOR pathway.
Topics: 5'-Nucleotidase; Adult; AMP-Activated Protein Kinases; Cell Proliferation; Cells, Cultured; Down-Regulation; Female; GPI-Linked Proteins; Healthy Volunteers; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-17; Male; Methotrexate; Middle Aged; Phosphorylation; Primary Cell Culture; Psoriasis; Signal Transduction; T-Lymphocytes, Regulatory; TOR Serine-Threonine Kinases; Up-Regulation; Young Adult | 2018 |
Risk of fragility fracture among patients with late-onset psoriasis: a UK population-based study.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Case-Control Studies; Cohort Studies; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Incidence; Male; Medical Record Linkage; Methotrexate; Middle Aged; Osteoporotic Fractures; Psoriasis; Risk Assessment; United Kingdom | 2018 |
Targeting the Plasticity of Psoriasis.
Topics: Animals; Benzimidazoles; Dermatologic Agents; Humans; Methotrexate; Mice; Psoriasis | 2018 |
Simultaneous Response in Several Domains in Patients with Psoriatic Disease Treated with Etanercept as Monotherapy or in Combination with Conventional Synthetic Disease-modifying Antirheumatic Drugs.
Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Drug Therapy, Combination; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Quality of Life; Treatment Outcome | 2018 |
Biological treatment for psoriasis and the risk of herpes zoster: results from the Psoriasis Longitudinal Assessment and Registry (PSOLAR).
Topics: Adult; Aged; Biological Factors; Female; Herpes Zoster; Humans; Immunologic Factors; Infliximab; Male; Methotrexate; Middle Aged; Phototherapy; Prevalence; Proportional Hazards Models; Prospective Studies; Psoriasis; Registries; Risk Factors; Ustekinumab | 2019 |
Long-term real-life safety profile and effectiveness of fumaric acid esters in psoriasis patients: a single-centre, retrospective, observational study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dermatologic Agents; Drug Therapy, Combination; Esters; Female; Fumarates; Humans; Longitudinal Studies; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Retrospective Studies; Severity of Illness Index; Young Adult | 2018 |
Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: Real-world data from a nationwide cohort study in Taiwan.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Multivariate Analysis; Population Surveillance; Prevalence; Prognosis; Psoriasis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Taiwan | 2018 |
More than skin deep.
Topics: Dermatologic Agents; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer; Stomatitis | 2018 |
Drug utilization patterns and adherence in patients on systemic medications for the treatment of psoriasis: A retrospective, comparative cohort study.
Topics: Acitretin; Adalimumab; Adolescent; Adult; Aged; Biological Products; Drug Utilization; Etanercept; Female; Humans; Immunosuppressive Agents; Male; Medication Adherence; Methotrexate; Middle Aged; Propensity Score; Psoriasis; Retrospective Studies; Treatment Outcome; Ustekinumab; Young Adult | 2018 |
PHARMACOGENETIC EFFECTS OF METHOTREXATE (MTX) IN UKRAINIAN PATIENTS DEPENDING ON THE MTHFR GENOTYPES (CLINICAL CASES).
Topics: Adult; Dermatitis, Atopic; Female; Genotype; Humans; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Pregnancy; Pregnancy, Ectopic; Psoriasis; Ukraine; Young Adult | 2018 |
Scaly annular and concentric plaques.
Topics: Biopsy; Dermatologic Agents; Diagnosis, Differential; Drug Administration Routes; Exanthema; Humans; Male; Methotrexate; Physical Examination; Pruritus; Psoriasis; Skin; Treatment Outcome; Triamcinolone; Young Adult | 2018 |
Infliximab is associated with an increased risk of serious infection in patients with psoriasis in the U.K. and Republic of Ireland: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR).
Topics: Adult; Biological Factors; Dermatologic Agents; Female; Follow-Up Studies; Humans; Incidence; Infections; Infliximab; Ireland; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Registries; Severity of Illness Index; United Kingdom | 2019 |
Carbomer gel bearing methotrexate loaded lipid nanocontainers shows improved topical delivery intended for effective management of psoriasis.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Drug Delivery Systems; Humans; Hydrogels; Lipids; Methotrexate; Nanoparticles; Particle Size; Psoriasis; Rabbits; Skin; Skin Absorption | 2018 |
[Effect of methotrexate on regulation for the number of regulatory T cells and expression of Foxp3 in psoriasis].
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Case-Control Studies; Female; Forkhead Transcription Factors; Humans; Imiquimod; Immunosuppressive Agents; Lymphocyte Count; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Random Allocation; RNA, Messenger; Spleen; T-Lymphocytes, Regulatory | 2018 |
Effect of Age of Onset of Psoriasis on Clinical Outcomes with Systemic Treatment in the Psoriasis Longitudinal Assessment and Registry (PSOLAR).
Topics: Adalimumab; Adult; Age of Onset; Aged; Biological Products; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Longitudinal Studies; Male; Methotrexate; Middle Aged; Psoriasis; Registries; Severity of Illness Index; Treatment Outcome; Ustekinumab | 2018 |
Systemic Treatment of Moderate to Severe Psoriasis in Pediatric Patients in Galicia, Spain: A Descriptive Study.
Topics: Acitretin; Adolescent; Child; Comorbidity; Cross-Sectional Studies; Drug Utilization; Humans; Methotrexate; Phototherapy; Procedures and Techniques Utilization; Psoriasis; Spain | 2018 |
Effect of methotrexate monotherapy on T-cell subsets in the peripheral circulation in psoriasis.
Topics: Adolescent; Adult; Cohort Studies; Female; Flow Cytometry; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Phenotype; Psoriasis; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Th2 Cells; Treatment Outcome; Young Adult | 2019 |
Safety and effectiveness of conventional systemic therapy and biological drugs in patients with moderate to severe psoriasis and HIV infection: a retrospective multicenter study.
Topics: Adult; Biological Products; Etanercept; Female; HIV Infections; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Ustekinumab; Viral Load | 2019 |
What's new about the mechanism of methotrexate action in psoriasis?
Topics: AMP-Activated Protein Kinases; Humans; Methotrexate; Psoriasis; T-Lymphocytes, Regulatory; TOR Serine-Threonine Kinases | 2018 |
Compounded topical preparations in plaque psoriasis: Still a place for it in 2018?
Topics: Administration, Cutaneous; Adult; Chronic Disease; Cyclosporine; Dermatologic Agents; Drug Compounding; Drug Substitution; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Remission Induction; Skin; Time Factors; Treatment Outcome | 2019 |
Potential Cardio-protective Effects of Psoriasis Medications.
Topics: Cardiovascular Diseases; Dermatologic Agents; Humans; Methotrexate; Phototherapy; Psoriasis; Tumor Necrosis Factor-alpha | 2018 |
Detailed ANA dynamics under adalimumab therapy show no significant correlation to PASI response and MTX cotreatment: a retrospective study of 98 psoriasis patients.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index | 2019 |
Successful therapy of plaque-type psoriasis with secukinumab in patients with multiple comorbidities treated with previous biologic therapies.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Therapy; Comorbidity; Cyclosporine; Etanercept; Female; Hepatitis B; Hepatitis C; Humans; Infliximab; Interleukin-17; Latent Tuberculosis; Male; Methotrexate; Middle Aged; Non-alcoholic Fatty Liver Disease; Psoriasis; Ustekinumab | 2018 |
Calcipotriol plus betamethasone dipropionate aerosol foam vs. apremilast, methotrexate, acitretin or fumaric acid esters for the treatment of plaque psoriasis: a matching-adjusted indirect comparison.
Topics: Acitretin; Administration, Cutaneous; Aerosols; Betamethasone; Calcitriol; Dermatologic Agents; Drug Therapy, Combination; Esters; Female; Fumarates; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Thalidomide; Treatment Outcome | 2019 |
Adverse Medical Conditions Across Treatment Options in Patients With Psoriasis: A Claims-Based Analysis
Topics: Adalimumab; Antirheumatic Agents; Biological Products; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Product Surveillance, Postmarketing; Psoriasis; PUVA Therapy; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Ustekinumab | 2018 |
Beliefs About Medicines in Patients with Psoriasis Treated with Methotrexate or Biologics: A Cross-sectional Survey Study.
Topics: Adult; Aged; Biological Products; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, Practice; Humans; Immunosuppressive Agents; Male; Medication Adherence; Methotrexate; Middle Aged; Psoriasis; Surveys and Questionnaires; Treatment Outcome | 2019 |
Genetic polymorphism predicting Methotrexate efficacy in Chinese patients with psoriasis vulgaris.
Topics: Adult; Aged; Asian People; Dermatologic Agents; Drug Resistance; Exome Sequencing; Female; Humans; Male; Metabolic Networks and Pathways; Methotrexate; Middle Aged; Mitochondrial Proteins; Muscle Proteins; Polymorphism, Single Nucleotide; Precision Medicine; Psoriasis; Severity of Illness Index; Telomerase; Treatment Outcome; Uroplakin Ia | 2019 |
TNF-α inhibitor-induced psoriasis: A decade of experience at the Cleveland Clinic.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Retrospective Studies; Risk Factors; Sex Factors; Spondylitis, Ankylosing; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2020 |
Psoriasis-associated progressive necrotizing posterior scleritis: A 6-year follow-up.
Topics: Arthritis, Psoriatic; Female; Fluorescein Angiography; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Psoriasis; Scleritis | 2020 |
Hesperidin inhibits keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis via the IRS-1/ERK1/2 pathway.
Topics: Animals; Blotting, Western; Cell Proliferation; Dermatologic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hesperidin; Humans; Imiquimod; Keratinocytes; Lipopolysaccharides; Male; MAP Kinase Signaling System; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Real-Time Polymerase Chain Reaction | 2019 |
Safety and Efficacy of Methotrexate for Chinese Adults With Psoriasis With and Without Psoriatic Arthritis.
Topics: Administration, Oral; Adult; Antirheumatic Agents; Arthritis, Psoriatic; China; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Patient Safety; Prognosis; Prospective Studies; Psoriasis; Reference Values; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome | 2019 |
Ocular findings in patients with psoriasis: is it related to the side effects of treatment or to psoriasis itself? A case-control study.
Topics: Acitretin; Adult; Case-Control Studies; Dermatologic Agents; Dry Eye Syndromes; Female; Humans; Logistic Models; Male; Methotrexate; Middle Aged; Odds Ratio; Prospective Studies; Psoriasis; Young Adult | 2020 |
Methotrexate efficacy and tolerance in plaque psoriasis. A prospective real-life multicentre study in France.
Topics: Adult; Cyclosporine; Dermatologic Agents; Female; Folic Acid; France; Humans; Male; Methotrexate; Middle Aged; Multivariate Analysis; Prospective Studies; Psoriasis; Treatment Outcome | 2019 |
Effects of topical methotrexate loaded gold nanoparticle in cutaneous inflammatory mouse model.
Topics: Administration, Topical; Animals; Disease Models, Animal; Drug Carriers; Gold; Immunosuppressive Agents; Metal Nanoparticles; Methotrexate; Mice; Mice, Inbred C57BL; Psoriasis; Sulfhydryl Compounds | 2019 |
Preventive and therapeutic effects of aqueous extract of Spinacia oleracea on Psoriatic patches in albino rats.
Topics: Animals; Dermatologic Agents; Disease Models, Animal; Female; Male; Methotrexate; Plant Extracts; Potassium Iodide; Psoriasis; Rats; Severity of Illness Index; Skin; Solvents; Spinacia oleracea; Water | 2019 |
Low dose acitretin versus methotrexate in the treatment of palmoplantar psoriasis: a case series.
Topics: Acitretin; Aged; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 2019 |
Acitretin-induced curling of hair in a Korean male.
Topics: Acitretin; Administration, Oral; Asian People; Drug Substitution; Hair; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Nail Diseases; Psoriasis; Republic of Korea; Treatment Outcome | 2019 |
cis-Khellactone Inhibited the Proinflammatory Macrophages via Promoting Autophagy to Ameliorate Imiquimod-Induced Psoriasis.
Topics: Adjuvants, Immunologic; Animals; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cells, Cultured; Coumarins; Disease Models, Animal; Female; Gene Knockdown Techniques; Hepatocytes; Humans; Imiquimod; Macrophages; Male; Methotrexate; Mice; Mice, Inbred C57BL; Primary Cell Culture; Psoriasis; Toxicity Tests | 2019 |
Drug survival of conventional systemic and biologic therapies for moderate-to-severe psoriasis in clinical practice in Spain: prospective results from the SAHARA study.
Topics: Acitretin; Adalimumab; Adolescent; Adult; Age of Onset; Biological Products; Cyclosporine; Dermatologic Agents; Etanercept; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Psoriasis; Spain; Ustekinumab | 2020 |
Methotrexate-induced eruptive lentiginosis in resolving psoriasis: a phenomenon possibly dependent on cytokine modulation.
Topics: Adult; Cytokines; Dermatologic Agents; Humans; Lentigo; Male; Methotrexate; Psoriasis; Skin | 2019 |
Down-regulation of miR-155 after treatment with narrow-band UVB and methotrexate associates with apoptosis of keratinocytes in psoriasis.
Topics: Apoptosis; Cell Proliferation; Down-Regulation; Humans; Keratinocytes; Methotrexate; MicroRNAs; Psoriasis; Ultraviolet Therapy | 2021 |
Enhanced skin permeation of Methotrexate from penetration enhancer containing vesicles: In vitro optimization and in vivo evaluation.
Topics: Administration, Cutaneous; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chemistry, Pharmaceutical; Drug Carriers; Female; Liposomes; Male; Methotrexate; Particle Size; Polyethylene Glycols; Polyethyleneimine; Psoriasis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Skin; Skin Absorption; Tissue Distribution | 2019 |
Fatal, incidental, idiopathic pulmonary fibrosis in a patient receiving long-term low-dose methotrexate for psoriasis.
Topics: Aged, 80 and over; Dermatologic Agents; Fatal Outcome; Humans; Idiopathic Pulmonary Fibrosis; Methotrexate; Psoriasis | 2019 |
Comment on 'Fatal, incidental, idiopathic pulmonary fibrosis in a patient receiving long-term low-dose methotrexate for psoriasis'.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Methotrexate; Psoriasis | 2019 |
Ustekinumab in Real-Life Practice: Experience in 116 Patients with Moderate-To-Severe Psoriasis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Ustekinumab; Young Adult | 2019 |
Lungs, methotrexate and psoriasis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Methotrexate; Psoriasis | 2019 |
Switching to secukinumab in difficult-to-treat psoriasis recalcitrant to methotrexate, cyclosporine and leflunomide, in a tuberculosis-endemic country.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Humans; Interleukin-17; Leflunomide; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Failure; Tuberculosis | 2019 |
Successful treatment of psoriatic crumbly nails with ustekinumab.
Topics: Aged; Humans; Male; Methotrexate; Nail Diseases; Psoriasis; Severity of Illness Index; Ustekinumab | 2019 |
Infiltration of T Cells into a Three-Dimensional Psoriatic Skin Model Mimics Pathological Key Features.
Topics: Cell Differentiation; Cell Movement; Cell Proliferation; Dermis; Epithelium; Female; Humans; Immunocompetence; Inflammation; Inflammation Mediators; Keratinocytes; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Models, Biological; Phenotype; Psoriasis; Signal Transduction; Skin; T-Lymphocytes | 2019 |
Lp-PLA2 as a promising predictor of comorbidities in patients with severe psoriasis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acitretin; Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Female; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Risk Factors; Young Adult | 2020 |
Comment on 'Fatal, incidental, idiopathic pulmonary fibrosis in a patient receiving long-term low-dose methotrexate for psoriasis': reply from author.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Methotrexate; Psoriasis | 2019 |
Persistence of apremilast in moderate-to-severe psoriasis: a real-world analysis of 14 147 apremilast- and methotrexate-naive patients in the French National Health Insurance database.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Male; Methotrexate; Middle Aged; National Health Programs; Psoriasis; Thalidomide | 2020 |
Reply to Gohar on 'Lungs, methotrexate and psoriasis', a comment on 'Fatal, incidental, idiopathic pulmonary fibrosis in a patient receiving long-term low-dose methotrexate for psoriasis'.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Lung; Methotrexate; Psoriasis | 2019 |
Response to 'Reply to Gohar on "Lungs, methotrexate and psoriasis", a comment on "Fatal, incidental, idiopathic pulmonary fibrosis in a patient receiving long-term low-dose methotrexate for psoriasis"'.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Lung; Methotrexate; Psoriasis | 2019 |
Th1, Th17, and Treg Responses are Differently Modulated by TNF-α Inhibitors and Methotrexate in Psoriasis Patients.
Topics: Adaptive Immunity; Adult; CD4-Positive T-Lymphocytes; Cytokines; Female; Healthy Volunteers; Humans; Immunologic Factors; Immunosuppressive Agents; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Psoriasis; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Tumor Necrosis Factor-alpha | 2019 |
Clinical Consequences of Antibody Formation, Serum Concentrations, and HLA-Cw6 Status in Psoriasis Patients on Ustekinumab.
Topics: Antibody Formation; Biomarkers; Female; HLA-C Antigens; Humans; Male; Methotrexate; Middle Aged; Netherlands; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome; Ustekinumab | 2019 |
Evaluation of the expression of the stromal cell-derived factor-1 alpha (CXCL 12) in psoriatic patients after treatment with Methotrexate.
Topics: Adult; Arthritis, Psoriatic; Biopsy; Case-Control Studies; Chemokine CXCL12; Disease Progression; Down-Regulation; Female; Humans; Keratinocytes; Male; Methotrexate; Psoriasis; Severity of Illness Index; Skin; Treatment Outcome | 2020 |
Psoriasis and liver fibrosis: an investigation using transient elastography in Tunisian patients with psoriasis.
Topics: Adult; Comorbidity; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prevalence; Psoriasis; Severity of Illness Index; Tunisia | 2019 |
Methotrexate-induced iatrogenic immunodeficiency-associated lymphoproliferative disorder causing hypercalcaemia.
Topics: Dermatologic Agents; Diagnosis, Differential; Female; Humans; Hypercalcemia; Immunologic Deficiency Syndromes; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Psoriasis; Sjogren's Syndrome | 2019 |
Diagnostic and therapeutic guidelines for plaque psoriasis - Brazilian Society of Dermatology.
Topics: Adrenal Cortex Hormones; Anthralin; Antibodies, Monoclonal; Brazil; Calcineurin Inhibitors; Comorbidity; Cyclosporine; Dermatologic Agents; Dermatology; Drug Combinations; Female; Humans; Male; Methotrexate; Phototherapy; Psoriasis; Severity of Illness Index; Societies, Medical; Time Factors; Vitamin D | 2019 |
Painful erosions on psoriatic plaques: cutaneous clue to life-threatening methotrexate overdose.
Topics: Buffers; Dermatologic Agents; Drug Overdose; Fluid Therapy; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer; Sodium Bicarbonate; Treatment Outcome | 2019 |
Factors that may influence the choice for initiating apremilast or methotrexate treatment for psoriasis in real-world clinical setting.
Topics: Adult; Aged; Clinical Decision-Making; Cross-Sectional Studies; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Thalidomide | 2019 |
Bleeding erosions in a man with psoriasis.
Topics: Adult; Antidotes; Drug-Related Side Effects and Adverse Reactions; Early Diagnosis; Hemorrhage; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Mucous Membrane; Pancytopenia; Psoriasis; Skin; Treatment Outcome; Withholding Treatment | 2020 |
Adalimumab-induced scalp psoriasis with severe alopecia.
Topics: Adalimumab; Adult; Alopecia; Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Scalp | 2019 |
Precision dosage of methotrexate in psoriasis.
Topics: Asian People; DNA-Binding Proteins; Genotype; Humans; Methotrexate; Prospective Studies; Psoriasis | 2019 |
Subcutaneous methotrexate versus oral form for the treatment and prophylaxis of chronic plaque psoriasis.
Topics: Administration, Oral; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Injections, Subcutaneous; Male; Methotrexate; Prognosis; Psoriasis; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome | 2019 |
A retrospective analysis of combination methotrexate-cyclosporine therapy in moderate-severe psoriasis.
Topics: Adult; Combined Modality Therapy; Cyclosporine; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; India; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome | 2014 |
Methotrexate toxicity presenting as cutaneous ulcerations on psoriatic plaques.
Topics: Aged; Folic Acid Antagonists; Humans; Male; Methotrexate; Psoriasis; Skin; Skin Ulcer | 2013 |
Serum prolidase activity in psoriasis patients.
Topics: Dipeptidases; Humans; Methotrexate; Psoriasis; PUVA Therapy | 2013 |
CD147 promotes MTX resistance by immune cells through up-regulating ABCG2 expression and function.
Topics: Adolescent; Adult; Aged; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Basigin; Case-Control Studies; Child; CHO Cells; Cricetinae; Cricetulus; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Resistance; Female; HEK293 Cells; Humans; Jurkat Cells; Leukocytes, Mononuclear; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Protein Binding; Protein Interaction Domains and Motifs; Psoriasis; RNA Interference; Transfection; Up-Regulation; Young Adult | 2013 |
Remission of bullous pemphigoid after rituximab treatment in a psoriasis patient on regular low-dose methotrexate.
Topics: Aged, 80 and over; Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Drug Therapy, Combination; Humans; Immunologic Factors; Immunosuppressive Agents; Induction Chemotherapy; Male; Methotrexate; Pemphigoid, Bullous; Prednisolone; Psoriasis; Rituximab | 2014 |
Serum prolidase may not accurately provide information to clinicians about the psoriasis activity.
Topics: Dipeptidases; Humans; Methotrexate; Psoriasis; PUVA Therapy | 2013 |
Combination therapy for psoriasis in the United States.
Topics: Calcitriol; Dermatologic Agents; Drug Therapy, Combination; Glucocorticoids; Health Care Surveys; Humans; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Time Factors; United States | 2013 |
Effect of the systemic use of methotrexate on the oxidative stress and paraoxonase enzyme in psoriasis patients.
Topics: Antioxidants; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Humans; Methotrexate; Psoriasis | 2013 |
Effect of serum folate status on total folate and 5-methyltetrahydrofolate in human skin.
Topics: Adult; Animals; Chromatography, High Pressure Liquid; Female; Folic Acid; gamma-Glutamyl Hydrolase; Humans; Linear Models; Methotrexate; Middle Aged; Psoriasis; Rats; Rats, Sprague-Dawley; Skin; Skin Physiological Phenomena; Tetrahydrofolates | 2013 |
Using Hawthorne effects to improve adherence in clinical practice: lessons from clinical trials.
Topics: Anti-Inflammatory Agents; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Ultraviolet Therapy | 2013 |
Using Hawthorne effects to improve adherence in clinical practice: lessons from clinical trials--reply.
Topics: Anti-Inflammatory Agents; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Ultraviolet Therapy | 2013 |
Remembering Yellapragada SubbaRow.
Topics: Aminopterin; Dermatologic Agents; History, 20th Century; India; Methotrexate; Psoriasis; United States | 2013 |
Treatment of psoriasis with non-registered fumaric acid esters in The Netherlands: a nationwide survey among Dutch dermatologists.
Topics: Biological Products; Cross-Sectional Studies; Dermatology; Fumarates; Health Surveys; Humans; Methotrexate; Netherlands; Practice Patterns, Physicians'; Psoriasis; Severity of Illness Index; Treatment Outcome | 2014 |
Biomarkers for methotrexate-induced liver injury: urinary protein profiling of psoriasis patients.
Topics: Adolescent; Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Proteomics; Psoriasis; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics, Nonparametric; Young Adult | 2013 |
Cancer-free survival of psoriasis patients treated with methotrexate and cyclosporine combination.
Topics: Adult; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Surveys and Questionnaires; Turkey | 2014 |
Undertreatment, treatment trends, and treatment dissatisfaction among patients with psoriasis and psoriatic arthritis in the United States: findings from the National Psoriasis Foundation surveys, 2003-2011.
Topics: Adult; Aged; Arthritis, Psoriatic; Data Collection; Dermatologic Agents; Female; Humans; Insurance Coverage; Male; Methotrexate; Middle Aged; Patient Satisfaction; Phototherapy; Practice Patterns, Physicians'; Psoriasis; Severity of Illness Index; Treatment Outcome; United States | 2013 |
Impact of methotrexate on oxidative stress and apoptosis markers in psoriatic patients.
Topics: Adolescent; Adult; Aged; Antioxidants; Apoptosis; Dermatologic Agents; Female; Humans; Male; Malondialdehyde; Methotrexate; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Psoriasis; Reactive Oxygen Species; Young Adult | 2014 |
Clinical profile, morbidity, and outcome of adult-onset generalized pustular psoriasis: analysis of 102 cases seen in a tertiary hospital in Johor, Malaysia.
Topics: Adult; Age Distribution; Age of Onset; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Cohort Studies; Dermatologic Agents; Developing Countries; Female; Hospitalization; Humans; Immunosuppressive Agents; Incidence; Malaysia; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Psoriasis; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Distribution; Statistics, Nonparametric; Tertiary Care Centers; Treatment Outcome; Young Adult | 2014 |
Effectiveness of systemic treatment agents on psoriatic nails: a comparative study.
Topics: Acitretin; Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Factors; Combined Modality Therapy; Dermatologic Agents; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Keratolytic Agents; Male; Methotrexate; Middle Aged; Nail Diseases; Nails; Onycholysis; Phototherapy; Psoriasis; Receptors, Tumor Necrosis Factor | 2013 |
Red clover causing symptoms suggestive of methotrexate toxicity in a patient on high-dose methotrexate.
Topics: Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Interactions; Drug Overdose; Female; Flushing; Humans; Menopause; Methotrexate; Middle Aged; Plant Extracts; Psoriasis; Trifolium; Withholding Treatment | 2013 |
Development and characterization of nanocarriers for topical treatment of psoriasis by using combination therapy.
Topics: Administration, Topical; Animals; Combined Modality Therapy; Disease Models, Animal; Humans; Liposomes; Methotrexate; Mice, Inbred Strains; Nanospheres; Orthokeratologic Procedures; Parakeratosis; Photochemotherapy; Psoriasis; Trioxsalen; Ultraviolet Therapy | 2014 |
Combination use of ustekinumab with other systemic therapies: a retrospective study in a tertiary referral center.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Biological Products; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Retinoids; Retrospective Studies; Tertiary Care Centers; Ustekinumab | 2013 |
Etanercept urticaria in a patient with psoriasis desensitized using a new method.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dermatologic Agents; Desensitization, Immunologic; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Keratoderma, Palmoplantar; Methotrexate; Methylprednisolone; Psoriasis; Receptors, Tumor Necrosis Factor; Urticaria | 2013 |
Dimethylfumarate induces apoptosis in human mast cells.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Calcium; Caspase 6; Caspase 9; Cell Death; Cell Line; Dermatologic Agents; Dexamethasone; Dimethyl Fumarate; Etoposide; Fumarates; Humans; Interleukin-8; Maleates; Mast Cells; Methotrexate; Psoriasis; TNF-Related Apoptosis-Inducing Ligand | 2013 |
Bullous drug eruption in a patient with psoriasis after a test dose of methotrexate.
Topics: Adult; Blister; Dermatologic Agents; Drug Eruptions; Humans; Male; Methotrexate; Psoriasis; Skin Tests | 2013 |
Considerable variation among Iranian dermatologists in the dosing and monitoring of methotrexate for treating psoriasis.
Topics: Contraindications; Dermatologic Agents; Dermatology; Drug Monitoring; Female; Humans; Iran; Male; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Surveys and Questionnaires | 2014 |
Partial reversal of androgenetic alopecia with methotrexate therapy for psoriasis.
Topics: Alopecia; Dermatologic Agents; Hair; Hair Follicle; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Scalp | 2013 |
Methotrexate toxicity induced by ciprofloxacin leading to psoriatic plaque ulceration: a case report.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Dermatologic Agents; Drug Interactions; Female; Humans; Methotrexate; Psoriasis | 2013 |
The methotrexate polyglutamate assay supports the efficacy of methotrexate for severe inflammatory skin disease in children.
Topics: Administration, Oral; Adolescent; Age Factors; Child; Child, Preschool; Cohort Studies; Dermatitis; Dermatitis, Atopic; Dose-Response Relationship, Drug; Drug Administration Schedule; Eczema; Female; Follow-Up Studies; Humans; Male; Methotrexate; Polyglutamic Acid; Psoriasis; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2014 |
Long-term durability and dose escalation patterns in infliximab therapy for psoriasis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Cohort Studies; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infliximab; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2014 |
Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study.
Topics: Adult; Age Distribution; Aged; Case-Control Studies; Cohort Studies; Comorbidity; Confidence Intervals; Databases, Factual; Diabetes Mellitus, Type 2; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Prevalence; Prognosis; Proportional Hazards Models; Psoriasis; Risk Assessment; Severity of Illness Index; Sex Distribution; Statistics, Nonparametric; Taiwan; Thiazides | 2014 |
Factors associated with the prescription of "traditional" or "biological" systemic treatment in psoriasis.
Topics: Adalimumab; Adolescent; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Dermatologic Agents; Etanercept; Female; Humans; Immunoglobulin G; Immunologic Factors; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Retrospective Studies; Young Adult | 2015 |
Widespread skin necrosis due to methotrexate overdose in a patient with CKD.
Topics: Drug Overdose; Humans; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Renal Insufficiency, Chronic; Skin | 2014 |
Prevalence of human polyomavirus DNA in eyebrow hairs plucked from patients with psoriasis treated with TNF inhibitors.
Topics: DNA, Viral; Eyebrows; Hair Removal; Humans; Immunosuppressive Agents; Merkel cell polyomavirus; Methotrexate; Polyomavirus; Prospective Studies; Psoriasis; Tumor Necrosis Factor-alpha | 2015 |
Effect of treatment with methotrexate and coal tar on adipokine levels and indices of insulin resistance and sensitivity in patients with psoriasis vulgaris.
Topics: Adiponectin; Adolescent; Adult; Aged; Case-Control Studies; Coal Tar; Female; Humans; Immunosuppressive Agents; Insulin Resistance; Interleukin-6; Keratolytic Agents; Leptin; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Resistin; Severity of Illness Index; Young Adult | 2015 |
'Short-term treatment with methotrexate does not affect microvascular endothelial function in patients with psoriasis'.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Humans; Immunosuppressive Agents; Methotrexate; Microvessels; Middle Aged; Prospective Studies; Psoriasis; Young Adult | 2015 |
Risk of adverse events in psoriasis patients receiving classic systemic drugs and biologics in a 5-year observational study of clinical practice: 2008-2013 results of the Biobadaderm registry.
Topics: Acitretin; Adalimumab; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Cyclosporine; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Keratolytic Agents; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Prospective Studies; Psoriasis; Receptors, Tumor Necrosis Factor; Registries; Risk Assessment; Spain; Ustekinumab | 2015 |
Initiation of TNF inhibitor therapy and change in physiologic measures in psoriasis.
Topics: Adult; Aged; Antibodies, Monoclonal; Blood Glucose; Blood Pressure; Body Mass Index; Dermatologic Agents; Energy Metabolism; Female; Follow-Up Studies; Humans; Infliximab; Lipids; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha | 2014 |
Current practice of methotrexate use for psoriasis: results of a worldwide survey among dermatologists.
Topics: Adult; Aged; Aged, 80 and over; Contraindications; Dermatology; Female; Humans; Male; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Psoriasis; Surveys and Questionnaires | 2015 |
Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells.
Topics: Aminoquinolines; Animals; CD11c Antigen; CD4-Positive T-Lymphocytes; Cytokines; Dermatitis; DNA, Complementary; Female; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Methotrexate; Mice; Mice, Inbred BALB C; Peptides; Permeability; Psoriasis; Skin | 2014 |
Erythrodermic psoriasis with bullous pemphigoid: combination treatment with methotrexate and compound glycyrrhizin.
Topics: Aged; Biopsy; Dermatitis, Exfoliative; Dermatologic Agents; Drug Therapy, Combination; Glycyrrhizic Acid; Humans; Male; Methotrexate; Microscopy, Fluorescence; Pemphigoid, Bullous; Psoriasis; Skin; Treatment Outcome | 2014 |
Solar burn reactivation reaction: an unusual side effect of methotrexate.
Topics: Dermatologic Agents; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Sunburn | 2014 |
Hyaluronic acid in psoriasis.
Topics: Biomarkers; Female; Fibrosis; Humans; Male; Methotrexate; Psoriasis | 2015 |
MicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Case-Control Studies; Female; Gene Expression Profiling; Genetic Markers; Genetic Testing; Humans; Immunosuppressive Agents; Male; Methotrexate; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Psoriasis; Real-Time Polymerase Chain Reaction; ROC Curve; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2014 |
Frequency of monoclonal gammopathy in psoriatic patients receiving anti-TNF therapy compared with patients taking conventional drugs: a cross-sectional study.
Topics: Acitretin; Adalimumab; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Cyclosporine; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Keratolytic Agents; Male; Methotrexate; Middle Aged; Monoclonal Gammopathy of Undetermined Significance; Prevalence; Psoriasis; Tumor Necrosis Factor-alpha | 2015 |
Guideline vs. practice in procollagen-3-aminopeptide monitoring.
Topics: Collagen Type III; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Practice Guidelines as Topic; Psoriasis; Retrospective Studies | 2014 |
Validity of noninvasive markers of methotrexate-induced hepatotoxicity: a retrospective cohort study.
Topics: Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Life Style; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Pilot Projects; Procollagen; Psoriasis; Retrospective Studies; ROC Curve | 2014 |
The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Biopsy; Body Mass Index; Chemical and Drug Induced Liver Injury; Drug Monitoring; Elasticity Imaging Techniques; Fatty Liver; Female; Fibrosis; Humans; Immunosuppressive Agents; Liver; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis; Young Adult | 2014 |
Methotrexate and cyclosporine in psoriasis revisited.
Topics: Cyclosporine; Humans; Methotrexate; Psoriasis | 2014 |
Latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint.
Topics: Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Arthritis, Rheumatoid; Clinical Trials, Phase III as Topic; Endpoint Determination; Humans; Injections, Subcutaneous; Methotrexate; Models, Statistical; Multicenter Studies as Topic; Psoriasis; Randomized Controlled Trials as Topic; Reproducibility of Results; Ustekinumab | 2014 |
Methotrexate use and liver disease--a causal relationship?
Topics: Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2014 |
Psoriasis: the new and the old.
Topics: Dermatologic Agents; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Ustekinumab | 2014 |
Trends in systemic psoriasis treatment therapies from 1993 through 2010.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Cyclosporine; Dermatologic Agents; Dermatology; Humans; Methotrexate; Phototherapy; Psoriasis; Retinoids; Severity of Illness Index; Surveys and Questionnaires; United States | 2014 |
The use of self-administered subcutaneous methotrexate for the treatment of psoriasis.
Topics: Dermatologic Agents; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis; Self Administration | 2014 |
Primary thyroid marginal zone B-cell lymphoma in a patient with psoriatic arthritis treated with etanercept.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Lymphoma, B-Cell, Marginal Zone; Methotrexate; Middle Aged; Psoriasis; Radiotherapy, Adjuvant; Rare Diseases; Receptors, Tumor Necrosis Factor; Recurrence; Retreatment; Risk Assessment; Severity of Illness Index; Thyroid Neoplasms; Thyroidectomy; Treatment Refusal | 2014 |
Effects of anti-TNF-α agents on circulating endothelial-derived and platelet-derived microparticles in psoriasis.
Topics: Antibodies, Monoclonal; Blood Platelets; Cardiovascular Diseases; Cell-Derived Microparticles; Dermatologic Agents; Endothelial Cells; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2014 |
Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting.
Topics: Acitretin; Adalimumab; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cross-Sectional Studies; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Young Adult | 2014 |
A comparative study of histopathological findings in skin biopsies from patients with psoriasis before and after treatment with acitretin, methotrexate and phototherapy.
Topics: Acitretin; Adult; Biopsy; Female; Humans; Male; Methotrexate; Phototherapy; Psoriasis; Severity of Illness Index; Skin; Treatment Outcome | 2015 |
Rupioid psoriasis and other skin diseases with rupioid manifestations.
Topics: Administration, Oral; Adult; Back; Dermatologic Agents; Diagnosis, Differential; Extremities; Humans; Male; Methotrexate; Psoriasis; Scalp Dermatoses; Thorax | 2014 |
Palmoplantar pustular psoriasis following initiation of a beta-blocker: disease control with low-dose methotrexate.
Topics: Adrenergic beta-Antagonists; Aged; Dermatologic Agents; Diagnosis, Differential; Drug Administration Schedule; Female; Humans; Methotrexate; Psoriasis | 2014 |
Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with severe psoriasis: 5-year follow-up of a Danish nationwide cohort.
Topics: Adult; Aged; Anti-Inflammatory Agents; Biological Products; Cardiovascular Diseases; Cause of Death; Climatotherapy; Cyclosporine; Denmark; Dermatologic Agents; Female; Follow-Up Studies; Humans; Incidence; Longitudinal Studies; Male; Methotrexate; Middle Aged; Myocardial Infarction; Phototherapy; Psoriasis; Registries; Retinoids; Severity of Illness Index; Stroke; Tumor Necrosis Factor-alpha; Ustekinumab | 2015 |
Fatal thrombotic thrombocytopenic purpura in a psoriasis patient treated with ustekinumab and methotrexate.
Topics: Adult; Dermatologic Agents; Fatal Outcome; Humans; Immunosuppressive Agents; Male; Methotrexate; Multiple Organ Failure; Psoriasis; Purpura, Thrombotic Thrombocytopenic; Ustekinumab | 2015 |
Acute severe methotrexate toxicity in patients with psoriasis: a case series and discussion.
Topics: Acute Disease; Aged, 80 and over; Atrial Fibrillation; Deglutition Disorders; Drug Eruptions; Dyslipidemias; Fever; Humans; Hypertension; Immunosuppressive Agents; Male; Medication Errors; Methotrexate; Middle Aged; Oral Ulcer; Pancytopenia; Psoriasis; Renal Insufficiency, Chronic; Shock, Septic | 2014 |
The 'switcher' patient profile in psoriasis treatment: from traditional to biological and from biological to traditional systemic drugs.
Topics: Acitretin; Adalimumab; Adult; Aged; Biological Factors; Cyclosporine; Dermatologic Agents; Drug Substitution; Etanercept; Female; Humans; Infliximab; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Psoriasis; Ustekinumab; Young Adult | 2015 |
Efficacy of adalimumab and methotrexate combination therapy on generalized pustular psoriasis patients unresponsive to infliximab monotherapy due to anti-infliximab antibody development.
Topics: Adalimumab; Adult; Antirheumatic Agents; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Psoriasis; Treatment Failure | 2015 |
Skin manifestations associated with chronic recurrent multifocal osteomyelitis in a 9-year-old girl.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Child; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Muscular Atrophy; Naproxen; Osteomyelitis; Paronychia; Psoriasis | 2014 |
A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers.
Topics: Administration, Cutaneous; Animals; Dermatologic Agents; Drug Carriers; Drug Compounding; Drug Liberation; In Vitro Techniques; Lipids; Methotrexate; Nanoparticles; Particle Size; Psoriasis; Skin; Skin Absorption; Surface Properties; Swine | 2014 |
Methotrexate in pediatric plaque-type psoriasis: Long-term daily clinical practice results from the Child-CAPTURE registry.
Topics: Adolescent; Anthralin; Body Surface Area; Child; Child, Preschool; Dermatologic Agents; Female; Humans; Kaplan-Meier Estimate; Longitudinal Studies; Male; Methotrexate; Phototherapy; Prospective Studies; Psoriasis; Quality of Life; Registries; Treatment Outcome | 2015 |
Long-term study of infliximab for psoriasis in daily practice: drug survival depends on combined treatment, obesity and infusion reactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Cohort Studies; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infliximab; Infusion Pumps; Kaplan-Meier Estimate; Longitudinal Studies; Male; Methotrexate; Middle Aged; Models, Statistical; Obesity; Psoriasis; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2014 |
The quest for an evidence-based approach to surveillance for methotrexate-related hepatotoxicity: promise and perils.
Topics: Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 2015 |
Gastric mucosa-associated lymphoid tissue lymphoma in a patient with severe psoriasis receiving ustekinumab.
Topics: Aged; Antirheumatic Agents; Disease Susceptibility; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoma, B-Cell, Marginal Zone; Male; Methotrexate; Psoriasis; PUVA Therapy; Stomach Neoplasms; Ustekinumab | 2015 |
Local reaction after subcutaneous injection of methotrexate: uncommon side effect.
Topics: Adult; Drug Eruptions; Humans; Immunosuppressive Agents; Injections, Subcutaneous; Male; Methotrexate; Psoriasis; Skin | 2016 |
Elevation of serum KL-6 in patients with psoriasis treated with anti-tumour necrosis factor-α therapy.
Topics: Adult; Aged; Biomarkers; Female; Humans; Immunosuppressive Agents; Immunotherapy; Lung Diseases, Interstitial; Male; Methotrexate; Middle Aged; Mucin-1; Psoriasis; Tumor Necrosis Factor-alpha | 2016 |
Variability in the prescription of non-biologic disease-modifying antirheumatic drugs for the treatment of spondyloarthritis in Spain.
Topics: Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Cyclosporine; Female; Humans; Inflammatory Bowel Diseases; Isoxazoles; Leflunomide; Logistic Models; Male; Methotrexate; Middle Aged; Odds Ratio; Practice Patterns, Physicians'; Psoriasis; Retrospective Studies; Severity of Illness Index; Sex Factors; Spain; Spondylarthropathies; Sulfasalazine; Uveitis | 2015 |
Arthritis possibly induced and exacerbated by a tumour necrosis factor antagonist in a patient with psoriasis vulgaris.
Topics: Adalimumab; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Dermatologic Agents; Drug Substitution; Drug Therapy, Combination; Humans; Male; Methotrexate; Psoriasis; Ustekinumab | 2015 |
Successful Elimination of Methotrexate by Continuous Veno-venous Haemofiltration in a Psoriatic Patient with Methotrexate Intoxication.
Topics: Disease Progression; Drug Overdose; Fatal Outcome; Hemofiltration; Humans; Male; Methotrexate; Middle Aged; Palliative Care; Psoriasis; Risk Assessment; Severity of Illness Index | 2015 |
[Methotrexate-associated photosensitization].
Topics: Adult; Arthritis, Psoriatic; Combined Modality Therapy; Humans; Male; Methotrexate; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Psoriasis; Radiodermatitis; Risk Factors; Skin Neoplasms; Ultraviolet Therapy | 2015 |
How are we using systemic drugs to treat psoriasis in children? An insight into current clinical U.K. practice.
Topics: Acitretin; Adolescent; Child; Child, Preschool; Cyclosporine; Dapsone; Dermatologic Agents; Fumarates; Humans; Immunosuppressive Agents; Methotrexate; Practice Patterns, Physicians'; Psoriasis; United Kingdom | 2015 |
Systemic antipsoriatic combination therapy with fumaric acid esters for plaque-type psoriasis: report on 17 cases.
Topics: Acitretin; Adult; Aged; Anti-Inflammatory Agents; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Fumarates; Germany; Humans; Infliximab; Isoxazoles; Keratolytic Agents; Leflunomide; Male; Methotrexate; Middle Aged; Prednisolone; Psoriasis; Retrospective Studies | 2015 |
Risk Factor Analysis for the Immunogenicity of Adalimumab Associated with Decreased Clinical Response in Chinese Patients with Psoriasis.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; China; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk Factors; Severity of Illness Index | 2015 |
No association between TNF inhibitor and methotrexate therapy versus methotrexate in changes in hemoglobin A1C and fasting glucose among psoriasis, psoriatic arthritis, and rheumatoid arthritis patients.
Topics: Aged; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Glucose; Cohort Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glycated Hemoglobin; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Tumor Necrosis Factor-alpha | 2015 |
[Methotrexate and psoriasis: about 46 cases].
Topics: Adolescent; Adult; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Retrospective Studies; Young Adult | 2014 |
Association between tumor necrosis factor inhibitor (TNFi) therapy and changes in C-reactive protein (CRP), blood pressure, and alanine aminotransferase (ALT) among patients with psoriasis, psoriatic arthritis, or rheumatoid arthritis.
Topics: Alanine Transaminase; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Pressure; C-Reactive Protein; Cohort Studies; Humans; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Tumor Necrosis Factor-alpha | 2015 |
Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study.
Topics: Administration, Cutaneous; Animals; Area Under Curve; Chemistry, Pharmaceutical; Cholesterol; Dermatologic Agents; Drug Carriers; Hexoses; Liposomes; Male; Methotrexate; Microscopy, Electron, Transmission; Models, Statistical; Nanotechnology; Organophosphates; Particle Size; Psoriasis; Rats, Wistar; Skin; Skin Absorption; Solubility; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical | 2015 |
Systemic Therapy for Psoriasis and the Risk of Herpes Zoster: A 500,000 Person-year Study.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Biological Factors; Causality; Cohort Studies; Comorbidity; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Herpes Zoster; Herpes Zoster Vaccine; Humans; Incidence; Isoxazoles; Male; Methotrexate; Middle Aged; Multivariate Analysis; Phototherapy; Psoriasis; Risk Factors; Sex Distribution; Ustekinumab | 2015 |
Patients with psoriasis have insufficient knowledge of their risk of atherothrombotic disease and metabolic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Atherosclerosis; Depressive Disorder; Diabetes Mellitus; Female; Health Knowledge, Attitudes, Practice; Humans; Hypertension; Immunosuppressive Agents; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Obesity; Patient Education as Topic; Psoriasis; Risk Factors; Thrombosis; Young Adult | 2015 |
Combination therapy of methotrexate plus NBUVB phototherapy is more effective than methotrexate monotherapy in the treatment of chronic plaque psoriasis.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Ultraviolet Therapy; Young Adult | 2015 |
Factors associated with drug survival of methotrexate and acitretin in patients with psoriasis.
Topics: Acitretin; Administration, Oral; Adult; Age Factors; Aged; Arthritis, Psoriatic; Databases, Factual; Dermatologic Agents; Drug Prescriptions; Female; Folic Acid; Humans; Israel; Kaplan-Meier Estimate; Keratolytic Agents; Male; Medication Adherence; Metabolic Syndrome; Methotrexate; Middle Aged; Psoriasis | 2015 |
[A man with multiple mucosal lesions and pancytopenia].
Topics: Diagnosis, Differential; Folic Acid Deficiency; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis | 2015 |
A novel nanogel formulation of methotrexate for topical treatment of psoriasis: optimization, in vitro and in vivo evaluation.
Topics: Administration, Topical; Animals; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Drug Liberation; Methotrexate; Mice; Mice, Inbred BALB C; Nanogels; Polyethylene Glycols; Polyethyleneimine; Psoriasis; Random Allocation; Skin Absorption; Treatment Outcome | 2016 |
Diffuse Large B-Cell Lymphoma of the Gingiva in a Patient on Long-Term Use of Methotrexate Being Treated for Psoriasis.
Topics: Aged, 80 and over; Biopsy; Dermatologic Agents; Fatal Outcome; Gingival Neoplasms; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Psoriasis | 2015 |
Should self-destructive behavior affect a patient's access to scarce medical resources?
Topics: Adalimumab; Adult; Alcoholism; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Contraindications; Health Resources; Health Services Accessibility; Humans; Male; Methotrexate; Psoriasis; Self-Injurious Behavior | 2015 |
Complete reversion of anti-infliximab immunization by methotrexate combination in a patient with psoriasis.
Topics: Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Infliximab; Methotrexate; Middle Aged; Psoriasis | 2015 |
Low-dose methotrexate-induced skin toxicity: Keratinocyte dystrophy as a histologic marker.
Topics: Administration, Oral; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Biopsy, Needle; Cohort Studies; Dose-Response Relationship, Drug; Drug Eruptions; Female; Follow-Up Studies; Humans; Immunohistochemistry; Keratinocytes; Male; Methotrexate; Middle Aged; Pemphigoid, Bullous; Psoriasis; Rare Diseases; Retrospective Studies; Risk Assessment; Skin Ulcer | 2015 |
ACP Journal Club. Review: Methotrexate does not increase risk for lung disease in psoriasis, psoriatic arthritis, or IBD.
Topics: Arthritis, Psoriatic; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lung Diseases; Methotrexate; Psoriasis | 2015 |
Microemulsions mediated effective delivery of methotrexate hydrogel: more than a tour de force in psoriasis therapeutics.
Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Drug Carriers; HeLa Cells; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Lipids; Methotrexate; Mice; Mice, Inbred C57BL; Particle Size; Psoriasis; Rats; Rats, Wistar; Skin; Skin Absorption; Swine | 2016 |
Total cholesterol, lipoprotein, and triglyceride levels in tumor necrosis factor inhibitor-treated patients with psoriasis, psoriatic arthritis, or rheumatoid arthritis.
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Cholesterol; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Lipoproteins, HDL; Lipoproteins, LDL; Methotrexate; Psoriasis; Retrospective Studies; Triglycerides; Tumor Necrosis Factor-alpha | 2015 |
Essential Truths for the Care and Management of Moderate-to-Severe Psoriasis.
Topics: Acitretin; Adalimumab; Attitude of Health Personnel; Biological Products; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Infliximab; Methotrexate; Perception; Practice Patterns, Physicians'; Psoriasis | 2015 |
Biologic and Conventional Systemic Therapies Show Similar Safety and Efficacy in Elderly and Adult Patients With Moderate to Severe Psoriasis.
Topics: Acitretin; Adalimumab; Adolescent; Adult; Aged; Antibodies, Monoclonal; Biological Products; Certolizumab Pegol; Cyclosporine; Dermatologic Agents; Drug Prescriptions; Drug Therapy, Combination; Etanercept; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Practice Patterns, Physicians'; Psoriasis; Retrospective Studies; Severity of Illness Index; Ultraviolet Therapy; Ustekinumab; Young Adult | 2015 |
The Use of Methotrexate, Alone or in Combination With Other Therapies, for the Treatment of Palmoplantar Psoriasis.
Topics: Adalimumab; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Foot Dermatoses; Hand Dermatoses; Humans; Immunosuppressive Agents; Infliximab; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Psoriasis; Severity of Illness Index; Thalidomide; Ustekinumab; Young Adult | 2015 |
Drug safety of systemic treatments for psoriasis: results from The German Psoriasis Registry PsoBest.
Topics: Adalimumab; Biological Products; Biological Therapy; Cardiovascular Diseases; Cyclosporine; Dermatologic Agents; Etanercept; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Registries; Ustekinumab | 2015 |
Granulocyte and Monocyte Adsorption Apheresis for Generalized Pustular Psoriasis: Therapeutic Outcomes in Three Refractory Patients.
Topics: Adult; Blood Component Removal; Cyclosporine; Drug Resistance; Female; Granulocytes; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Monocytes; Phototherapy; Psoriasis; Severity of Illness Index; Treatment Outcome | 2015 |
Successful use of infliximab as first line treatment for severe childhood generalized pustular psoriasis.
Topics: Adult; Dermatologic Agents; Female; Humans; Infliximab; Methotrexate; Psoriasis; Severity of Illness Index | 2016 |
Can pretreatment serum calcium level predict the efficacy of methotrexate in the treatment of severe plaque psoriasis?
Topics: Adolescent; Adult; Aged; Animals; Area Under Curve; Biomarkers; Calcium; Cohort Studies; Disease Models, Animal; Female; Humans; Male; Methotrexate; Mice; Middle Aged; Predictive Value of Tests; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2015 |
Adherence of self-administered subcutaneous methotrexate in patients with chronic plaque-type psoriasis.
Topics: Chronic Disease; Dermatologic Agents; Female; Humans; Male; Methotrexate; Patient Compliance; Psoriasis; Self Administration | 2016 |
European S3-Guidelines on the systemic treatment of psoriasis vulgaris--Update 2015--Short version--EDF in cooperation with EADV and IPC.
Topics: Acitretin; Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Drug Therapy, Combination; Etanercept; Fumarates; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Psoriasis; Ustekinumab | 2015 |
Adalimumab-Induced Pityriasis Lichenoides Chronica That Responded Well to Methotrexate in a Patient With Psoriasis.
Topics: Adalimumab; Humans; Male; Methotrexate; Middle Aged; Pityriasis Lichenoides; Psoriasis | 2016 |
Algorithm to select optimal systemic anti-psoriatic drugs in relation with patients' Psoriasis Area and Severity Index score for plaque psoriasis.
Topics: Acitretin; Adolescent; Adult; Aged; Algorithms; Cyclosporine; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2016 |
Systemic treatments in childhood psoriasis: a French multicentre study on 154 children.
Topics: Acitretin; Adolescent; Child; Child, Preschool; Cyclosporine; Dermatologic Agents; France; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Phototherapy; Psoriasis; Treatment Outcome | 2016 |
Methotrexate regulates Th-1 response by suppressing caspase-1 and cytokines in psoriasis patients.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Caspase 1; Female; Gene Expression Regulation, Enzymologic; Humans; Interleukin-18; Male; Methotrexate; Middle Aged; Psoriasis; Skin; Th1 Cells; Tumor Necrosis Factor-alpha; Young Adult | 2016 |
Effect of antipsoriatic therapy on oxidative stress index and sialic acid levels in patients with psoriasis.
Topics: Administration, Topical; Adult; Age Factors; Biomarkers; C-Reactive Protein; Case-Control Studies; Cohort Studies; Female; Humans; India; Linear Models; Male; Methotrexate; Middle Aged; Multivariate Analysis; N-Acetylneuraminic Acid; Oxidative Stress; Prognosis; Psoriasis; Severity of Illness Index; Sex Factors; Statistics, Nonparametric; Tars; Treatment Outcome | 2016 |
[Spontaneous regression of multiple squamous cell carcinomas after discontinuation of adalimumab and methotrexate].
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Psoriatic; Carcinoma, Squamous Cell; Etanercept; Female; Humans; Methotrexate; Middle Aged; Neoplasm Regression, Spontaneous; Neoplasms, Multiple Primary; Psoriasis; Skin Neoplasms; Withholding Treatment | 2016 |
Retrospective analysis of the effectiveness and costs of traditional treatments for moderate-to-severe psoriasis: A single-center, Italian study.
Topics: Acitretin; Adult; Cyclosporine; Dermatologic Agents; Female; Humans; Italy; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Retrospective Studies; Treatment Outcome | 2016 |
Methotrexate in psoriasis under real-world conditions: long-term efficacy and tolerability.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Young Adult | 2016 |
Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis.
Topics: Administration, Cutaneous; Animals; Cell Survival; Cells, Cultured; Dermatologic Agents; Drug Liberation; Gold; Humans; Hydrophobic and Hydrophilic Interactions; Keratinocytes; Metal Nanoparticles; Methotrexate; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Psoriasis; Skin; Skin Absorption; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds | 2016 |
Psoriasis and the liver: problems, causes and course.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Child; Dermatologic Agents; Diabetes Complications; Female; Humans; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Young Adult | 2017 |
Topical psoriasis therapies and unmet patient needs: the importance of optimizing methotrexate.
Topics: Administration, Oral; Administration, Topical; Dermatologic Agents; Health Services Needs and Demand; Humans; Injections, Subcutaneous; Methotrexate; Psoriasis | 2016 |
Psoriatic Arthritis with Annular Pustular Psoriasis.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Psoriatic; Female; Humans; Methotrexate; Middle Aged; Prednisolone; Psoriasis; Treatment Outcome | 2016 |
Effectiveness of Subcutaneous Methotrexate in Chronic Plaque Psoriasis.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Biological Availability; Chronic Disease; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome; United Kingdom; Young Adult | 2016 |
[Annular plaque psoriasis].
Topics: Dermatologic Agents; Humans; Male; Methotrexate; Psoriasis; Young Adult | 2016 |
Cost-effectiveness of systemic treatments for moderate-to-severe psoriasis in the German health care setting.
Topics: Biological Products; Cost-Benefit Analysis; Germany; Health Care Costs; Humans; Infliximab; Insurance, Health, Reimbursement; Methotrexate; Psoriasis; Treatment Outcome; Ustekinumab | 2016 |
Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin.
Topics: Cardiotonic Agents; Cardiovascular Diseases; Clinical Trials as Topic; Gene Expression Regulation; Genomics; Humans; Methotrexate; Plaque, Atherosclerotic; Psoriasis; Skin | 2016 |
[Cost Effectiveness of Treatments of Psoriasis with a PASI 75 and one Period of 12 Weeks].
Topics: Acitretin; Adalimumab; Cost-Benefit Analysis; Cyclosporine; Etanercept; Health Care Costs; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Models, Economic; Psoriasis; PUVA Therapy; Severity of Illness Index; Spain; Time Factors; Treatment Outcome; Ultraviolet Therapy; Ustekinumab | 2016 |
Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Databases, Factual; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant, Newborn; Methotrexate; Piperidines; Pregnancy; Pregnancy Outcome; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Young Adult | 2016 |
Generalized pustular psoriasis treated with ustekinumab.
Topics: Acitretin; Adalimumab; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Cyclosporine; Drug Resistance; Female; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Psoriasis; Skin Diseases, Vesiculobullous; Treatment Outcome; Ustekinumab | 2016 |
Expert Recommendations on Treating Psoriasis in Special Circumstances (Part II).
Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Biological Therapy; Child; Clinical Trials as Topic; Combined Modality Therapy; Delphi Technique; Disease Management; Disease Susceptibility; Etanercept; Humans; Immunosuppressive Agents; Infections; Methotrexate; Psoriasis; Quality of Life; Surveys and Questionnaires; Ultraviolet Therapy | 2016 |
Psoriasis Patients Treated With Biologics and Methotrexate Have a Reduced Rate of Myocardial Infarction: A Collaborative Analysis Using International Cohorts.
Topics: Administration, Cutaneous; Administration, Oral; Biological Products; Canada; Cohort Studies; Comorbidity; Denmark; Dermatologic Agents; Humans; Incidence; Internationality; Kuwait; Methotrexate; Myocardial Infarction; Protective Factors; Psoriasis; Severity of Illness Index; Ultraviolet Therapy; United States | 2016 |
Methotrexate treatment provokes apoptosis of proliferating keratinocyte in psoriasis patients.
Topics: Adolescent; Adult; Aged; Apoptosis; Biopsy; Dermatologic Agents; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Profiling; Humans; Keratinocytes; Male; Methotrexate; Middle Aged; Psoriasis; Real-Time Polymerase Chain Reaction; Skin; Young Adult | 2017 |
Insights on methotrexate in psoriatic disease.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Cardiovascular Diseases; Humans; Methotrexate; Psoriasis | 2016 |
[Effect of acitretin and methotrexate on treatment of
severe plaque psoriasis].
Topics: Acitretin; Humans; Methotrexate; Psoriasis | 2016 |
Image Gallery: Complete remission of aggressive desmoid-type fibromatosis after low-dose methotrexate for 2 weeks in a child with psoriasis.
Topics: Adolescent; Dermatologic Agents; Female; Fibromatosis, Aggressive; Humans; Methotrexate; Psoriasis; Remission Induction | 2016 |
Infections in Moderate to Severe Psoriasis Patients Treated with Biological Drugs Compared to Classic Systemic Drugs: Findings from the BIOBADADERM Registry.
Topics: Adalimumab; Adult; Aged; Bacterial Infections; Biological Products; Cyclosporine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Poisson Distribution; Psoriasis; Registries | 2017 |
Low dose methotrexate induced asymptomatic keratinocyte dystrophy in a patient of psoriasis vulgaris.
Topics: Child; Dermatologic Agents; Drug Eruptions; Humans; Keratinocytes; Male; Methotrexate; Psoriasis | 2016 |
Treatment patterns in moderate-to-severe plaque psoriasis: results from a Belgian cross-sectional study (DISCOVER).
Topics: Adalimumab; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Belgium; Biological Products; Cross-Sectional Studies; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Severity of Illness Index; Treatment Outcome; Young Adult | 2017 |
Development of bullous pemphigoid in a patient with psoriasis and metabolic syndrome.
Topics: Adult; Autoantibodies; Dose-Response Relationship, Drug; Dystonin; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Metabolic Syndrome; Methotrexate; Pemphigoid, Bullous; Psoriasis; Treatment Outcome | 2016 |
A case of methotrexate intoxication in a patient with psoriasis who drank beetroot juice during methotrexate treatment.
Topics: Beta vulgaris; Dermatologic Agents; Female; Fruit and Vegetable Juices; Humans; Methotrexate; Middle Aged; Plant Extracts; Psoriasis; Skin Ulcer | 2016 |
Presenting treatment safety data: subjective interpretations of objective information.
Topics: Adalimumab; Communication; Dermatologic Agents; Humans; Infliximab; Methotrexate; Patient Education as Topic; Patient Safety; Psoriasis | 2016 |
The effect of tumor necrosis factor inhibitor therapy on the incidence of myocardial infarction in patients with psoriasis: a retrospective study.
Topics: Adalimumab; Administration, Topical; Adult; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Humans; Incidence; Infliximab; Male; Methotrexate; Middle Aged; Myocardial Infarction; Psoriasis; Retrospective Studies; Risk; Tumor Necrosis Factor-alpha | 2018 |
Cardiovascular event risk assessment in psoriasis patients treated with tumor necrosis factor-α inhibitors versus methotrexate.
Topics: Adalimumab; Adolescent; Adult; Aged; Angina, Unstable; Cardiovascular Diseases; Dermatologic Agents; Etanercept; Female; Humans; Infliximab; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Protective Factors; Psoriasis; Risk Assessment; Stroke; Time Factors; Tumor Necrosis Factor-alpha; Young Adult | 2017 |
Efficacy, safety and drug survival of conventional agents in pediatric psoriasis: A multicenter, cohort study.
Topics: Acitretin; Adolescent; Child; Cohort Studies; Cyclosporine; Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis; Treatment Outcome | 2017 |
Methotrexate Use and Monitoring in Patients with Psoriasis: A Consensus Report Based on a Danish Expert Meeting.
Topics: Adult; Age Factors; Chemical and Drug Induced Liver Injury; Child; Consensus; Denmark; Dermatology; Drug Dosage Calculations; Female; Humans; Immunosuppressive Agents; Liver Function Tests; Male; Methotrexate; Neoplasms; Patient Safety; Pregnancy; Pregnancy Complications; Psoriasis; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Effectiveness and safety of Methotrexate in psoriasis: an eight-year experience with 218 patients.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome | 2017 |
Should methotrexate remain the first-line drug for psoriasis?
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis | 2017 |
Biologic drug survival in Israeli psoriasis patients.
Topics: Acitretin; Adalimumab; Adult; Databases, Factual; Dermatologic Agents; Drug Substitution; Drug Therapy, Combination; Drug Tolerance; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Interleukin-12 Receptor beta 1 Subunit; Israel; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Psoriasis; Time Factors; Tumor Necrosis Factor-alpha; Ustekinumab | 2017 |
The investigation of antimicrobial peptides expression and its related interaction with methotrexate treatment in patients with psoriasis vulgaris.
Topics: Adult; beta-Defensins; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis | 2017 |
Determinants for drug survival of methotrexate in patients with psoriasis, split according to different reasons for discontinuation: results of the prospective MTX-CAPTURE.
Topics: Adult; Age of Onset; Dermatologic Agents; Drug Substitution; Female; Humans; Kaplan-Meier Estimate; Male; Methotrexate; Prospective Studies; Psoriasis; Registries | 2017 |
Procollagen-3 N-terminal peptide measurements for the detection of liver fibrosis in methotrexate-treated patients with psoriasis: daily practice use and clinical implications.
Topics: Biomarkers; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 2017 |
Real-world outcomes in 2646 psoriasis patients: one in five has PASI ≥10 and/or DLQI ≥10 under ongoing systemic therapy.
Topics: Adalimumab; Adult; Aged; Cross-Sectional Studies; Dermatologic Agents; Drug Administration Schedule; Etanercept; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Quality of Life; Registries; Severity of Illness Index; Ustekinumab | 2017 |
New onset or worsening of psoriasis following biologic therapy: A case series.
Topics: Adult; Aged; Biological Therapy; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis | 2017 |
Medication errors associated with oral administration of methotrexate. Data from spontaneous reporting and medical literature review.
Topics: Administration, Oral; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Male; Medication Errors; Methotrexate; Middle Aged; Psoriasis; Spain | 2017 |
Association of Therapy for Autoimmune Disease With Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Case-Control Studies; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Incidence; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Mycophenolic Acid; Myelodysplastic Syndromes; Odds Ratio; Psoriasis; Retrospective Studies; Risk Factors; United States | 2017 |
Psoriasis in systemic lupus erythematosus: a single-center experience.
Topics: Adolescent; Adult; Antirheumatic Agents; Azathioprine; Cohort Studies; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Male; Methotrexate; Ontario; Psoriasis; Young Adult | 2017 |
Characteristics and risk profile of psoriasis patients included in the Czech national registry BIOREP and a comparison with other registries.
Topics: Acitretin; Adult; Biological Products; Body Mass Index; Comorbidity; Coronary Disease; Cyclosporine; Czech Republic; Dermatologic Agents; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypertension; Keratolytic Agents; Male; Methotrexate; Middle Aged; Obesity; Phototherapy; Prevalence; Psoriasis; Quality of Life; Registries; Retreatment; Retrospective Studies; Risk Factors; Severity of Illness Index | 2017 |
Peristomal psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prevalence; Psoriasis; Surgical Stomas; Ultraviolet Therapy | 2017 |
Diagnostic performance of transient elastography for detection of methotrexate-induced liver injury using Roenigk classification in Asian patients with psoriasis: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Chemical and Drug Induced Liver Injury; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 2017 |
Mucocutaneous ulcerations secondary to methotrexate.
Topics: Administration, Oral; Adult; Drug Interactions; Female; Folic Acid Antagonists; Humans; Methotrexate; Mouth Mucosa; Oral Ulcer; Psoriasis; Skin; Skin Ulcer | 2008 |
Etanercept combined with methotrexate for high-need psoriasis.
Topics: Adult; Dermatologic Agents; Drug Evaluation; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2008 |
Overview of psoriasis: update on current and emerging treatment options.
Topics: Administration, Topical; Humans; Immunologic Factors; Methotrexate; Phototherapy; Prevalence; Psoriasis; Severity of Illness Index; Treatment Outcome; United States | 2003 |
Drug use and toxicity in psoriatic disease: focus on methotrexate.
Topics: Alcoholic Beverages; Antirheumatic Agents; Female; Humans; Liver Cirrhosis; Methotrexate; Pregnancy; Psoriasis | 2008 |
Systemic and light therapies for the management of childhood psoriasis: part II.
Topics: Biological Products; Child; Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Phototherapy; Psoriasis; Retinoids | 2008 |
Development of pemphigus vulgaris in a patient with psoriasis treated with etanercept.
Topics: Etanercept; Humans; Immunoglobulin G; Male; Methotrexate; Middle Aged; Pemphigus; Phototherapy; Prednisone; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2009 |
Increased insulin-like growth factor binding protein-3 expression level in psoriatic tissue before and after systemic treatment with cyclosporine A and methotrexate.
Topics: Adult; Cyclosporine; Dermatologic Agents; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Insulin-Like Growth Factor Binding Protein 3; Male; Methotrexate; Middle Aged; Psoriasis; Skin; Young Adult | 2008 |
Persistent CD4+ T cell depression following combination alefacept and methotrexate therapy.
Topics: Adolescent; Aged; Alefacept; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Recombinant Fusion Proteins | 2008 |
Multiple toxic effects of low-dose methotrexate in a patient treated for psoriasis.
Topics: Acute Kidney Injury; Aphasia; Dermatologic Agents; Drug Overdose; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Ulcer | 2008 |
Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; gamma-Glutamyl Hydrolase; Gastrointestinal Diseases; Haplotypes; Humans; Hydroxymethyl and Formyl Transferases; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Nucleotide Deaminases; Peptide Synthases; Polymorphism, Single Nucleotide; Psoriasis; Treatment Outcome | 2009 |
Liposomal methotrexate hydrogel for treatment of localized psoriasis: preparation, characterization and laser targeting.
Topics: Administration, Topical; Adolescent; Adult; Aged; Animals; Double-Blind Method; Female; Humans; Hydrogels; Immunosuppressive Agents; Liposomes; Male; Methotrexate; Mice; Middle Aged; Placebos; Psoriasis | 2008 |
Increasing use of more potent treatments for psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Biological Products; Calcitriol; Dermatologic Agents; Drug Utilization; Female; Humans; Male; Methotrexate; Middle Aged; Nonprescription Drugs; Practice Patterns, Physicians'; Psoriasis | 2009 |
Pustular psoriasis following treatment of rheumatoid arthritis with TNF-alpha inhibitors.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Dermatologic Agents; Etanercept; Female; Flurandrenolone; Foot; Hand; Humans; Immunoglobulin G; Isotretinoin; Keratolytic Agents; Methotrexate; Middle Aged; Prednisone; Psoriasis; Receptors, Tumor Necrosis Factor; Skin; Tumor Necrosis Factor-alpha | 2008 |
Severe erythroderma in a patient under intermittent therapy with efalizumab.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatitis, Exfoliative; Dermatologic Agents; Drug Eruptions; Hand; Humans; Hyperkeratosis, Epidermolytic; Male; Methotrexate; Middle Aged; Psoriasis; Skin | 2008 |
Economic evaluation of systemic therapies for moderate to severe psoriasis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cost-Benefit Analysis; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Infliximab; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Statistics as Topic; Time Factors; Treatment Outcome | 2009 |
Long-term control of recalcitrant psoriasis with combination infliximab and methotrexate.
Topics: Adult; Antibodies, Monoclonal; Dermatologic Agents; Drug Therapy, Combination; Humans; Infliximab; Male; Methotrexate; Psoriasis | 2009 |
Methotrexate treatment in 13 children with severe plaque psoriasis.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Retrospective Studies; Treatment Outcome | 2009 |
Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Eruptions; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Methotrexate; Middle Aged; Peritoneal Neoplasms; Piperazines; Psoriasis; Pyrimidines; Treatment Outcome | 2009 |
Long-term maintenance treatment of moderate-to-severe plaque psoriasis with infliximab in combination with methotrexate or azathioprine in a retrospective cohort.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Azathioprine; Child; Cohort Studies; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2009 |
Infectious complications in patients with psoriasis and rheumatoid arthritis treated with antitumor necrosis factor agents and methotrexate.
Topics: Arthritis, Rheumatoid; Bacterial Infections; Drug Therapy, Combination; Epidural Abscess; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2009 |
Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy.
Topics: Adult; Aged; Arthritis, Psoriatic; Biomarkers; Biopsy; Drug Monitoring; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Prospective Studies; Psoriasis; Risk Factors | 2009 |
Reduced libido and erectile dysfunction: rarely reported side-effects of methotrexate.
Topics: Dermatologic Agents; Erectile Dysfunction; Humans; Libido; Male; Methotrexate; Middle Aged; Psoriasis | 2009 |
Methotrexate: understanding the risk in psoriasis patients.
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis; Risk Assessment | 2009 |
Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference.
Topics: Child; Contraindications; Dermatologic Agents; Drug Interactions; Fertility; Humans; Male; Methotrexate; Patient Selection; Psoriasis; Spermatogenesis | 2009 |
Psoriatic plaque erosion: a rare side effect of methotrexate.
Topics: Female; Humans; Methotrexate; Middle Aged; Psoriasis | 2009 |
Eventration caused by methotrexate in a psoriatic patient.
Topics: Humans; Male; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer | 2010 |
A retrospective analysis of treatment responses of palmoplantar psoriasis in 114 patients.
Topics: Adolescent; Adult; Aged; Child; Cyclosporine; Female; Humans; Keratoderma, Palmoplantar; Male; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; Retinoids; Retrospective Studies; Treatment Outcome; Young Adult | 2009 |
[Prolonged fever and monocytosis after hemorrhoidectomy and treatment with methotrexate--listeriosis with cerebral abscess].
Topics: Anti-Infective Agents; Biopsy, Needle; Brain; Brain Abscess; Diagnosis, Differential; Drug Therapy, Combination; Fever; Hemorrhoids; Humans; Immunosuppressive Agents; Leukocytosis; Listeriosis; Magnetic Resonance Imaging; Male; Methotrexate; Metronidazole; Middle Aged; Monocytes; Penicillins; Psoriasis; Stereotaxic Techniques; Tomography, X-Ray Computed | 2009 |
Regression of chronic posterior leukoencephalopathy after stop of methotrexate treatment.
Topics: Administration, Oral; Apraxia, Ideomotor; Cerebral Cortex; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Posterior Leukoencephalopathy Syndrome; Psoriasis; Remission, Spontaneous; Treatment Outcome | 2009 |
Comment on: Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy.
Topics: Biomarkers; Drug Monitoring; Humans; Immunosuppressive Agents; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 2009 |
Folliculotropic mycosis fungoides in a psoriatic patient under methotrexate treatment.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Diagnosis, Differential; Female; Humans; Methotrexate; Mycosis Fungoides; Psoriasis; Skin Neoplasms | 2009 |
European S3-guidelines on the systemic treatment of psoriasis vulgaris.
Topics: Adalimumab; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Infliximab; Methotrexate; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retinoids | 2009 |
[Correct use of methotrexate].
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Psoriasis; Treatment Outcome | 2009 |
[Methotrexate: safe if prescribed correctly].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Medication Errors; Methotrexate; Psoriasis | 2009 |
Gallbladder squamous cell carcinoma in the setting of low-dose methotrexate use.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cholecystectomy, Laparoscopic; Cisplatin; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Female; Fluorouracil; Gallbladder Neoplasms; Gallstones; Humans; Incidental Findings; Liver Neoplasms; Methotrexate; Neoplasm Seeding; Peritoneal Neoplasms; Psoriasis | 2009 |
Daily practice assessment of liver injury in patients with psoriasis on methotrexate.
Topics: Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Collagen Type III; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Peptide Fragments; Psoriasis | 2010 |
Severe 20-nail psoriasis successfully treated by low dose methotrexate.
Topics: Administration, Oral; Biopsy, Needle; Child; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fingers; Follow-Up Studies; Humans; Immunohistochemistry; Methotrexate; Nail Diseases; Psoriasis; Severity of Illness Index; Toes; Treatment Outcome | 2009 |
Childhood psoriasis: often favorable outcome.
Topics: Acitretin; Administration, Topical; Anthralin; Calcitriol; Child; Cyclosporine; Dermatologic Agents; Emollients; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Nicotinic Acids; Plant Extracts; Psoriasis; Receptors, Tumor Necrosis Factor; Salicylates; Steroids; Tars; Treatment Outcome; Ultraviolet Therapy | 2009 |
Atypical presentation of histoplasmosis in a patient with psoriasis and psoriatic arthritis on infliximab therapy.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arthritis, Psoriatic; Drug Therapy, Combination; Female; Histoplasmosis; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Opportunistic Infections; Prednisone; Psoriasis; Tumor Necrosis Factor-alpha | 2010 |
High prevalence of potential drug-drug interactions for psoriasis patients prescribed methotrexate or cyclosporine for psoriasis: associated clinical and economic outcomes in real-world practice.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Drug Interactions; Female; Humans; Immunosuppressive Agents; Male; Managed Care Programs; Methotrexate; Middle Aged; Prevalence; Psoriasis; Retinoids | 2010 |
A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.
Topics: Anti-Inflammatory Agents; Aspirin; Chronic Disease; Colchicine; Dermatologic Agents; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Pericarditis; Pleurisy; Psoriasis | 2010 |
Painful nail lesions.
Topics: Clobetasol; Dermatologic Agents; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Nail Diseases; Onycholysis; Pain; Psoriasis; PUVA Therapy | 2010 |
Erythema gyratum repens-like eruption occuring in resolving psoriasis during methotrexate therapy.
Topics: Dermatologic Agents; Drug Eruptions; Erythema; Female; Histamine Antagonists; Humans; Methotrexate; Middle Aged; Psoriasis | 2010 |
Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay.
Topics: Anthralin; Anti-Infective Agents, Local; Caspase 3; Caspase 7; Cell Line; Cell Proliferation; Colorimetry; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; Fluorometry; Humans; Keratinocytes; Methotrexate; Psoriasis; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Thymidine | 2010 |
Efficacy study of vesicular gel containing methotrexate and menthol combination on parakeratotic rat skin model.
Topics: Administration, Topical; Animals; Dermatologic Agents; Diffusion Chambers, Culture; Disease Models, Animal; Drug Combinations; Drug Synergism; Gels; Humans; Immunodiffusion; Liposomes; Male; Menthol; Methotrexate; Parakeratosis; Permeability; Psoriasis; Rats; Rats, Wistar; Skin; Skin Absorption; Tissue Culture Techniques | 2011 |
Focal skin toxicity related to methotrexate sparing psoriatic plaques.
Topics: Antimetabolites, Antineoplastic; Drug Eruptions; Female; Folic Acid Antagonists; Histamine Antagonists; Humans; Methotrexate; Middle Aged; Psoriasis; Self Medication | 2010 |
Interleukin 4 or cytokine antagonists? Time to change the search for novel psoriasis therapies.
Topics: CD4-Positive T-Lymphocytes; Cytokines; Fumarates; Humans; Immunosuppressive Agents; Interleukin-4; Methotrexate; Psoriasis | 2010 |
Rapidly progressive destructive arthritis in psoriatic arthritis sine psoriasis: do bone resorption marker levels predict outcome of bone destruction in psoriatic arthritis?
Topics: Alkaline Phosphatase; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Psoriatic; Biomarkers; Bone Resorption; Collagen Type I; Disease Progression; Drug Therapy, Combination; Female; Humans; Infliximab; Methotrexate; Middle Aged; Peptides; Prognosis; Psoriasis | 2011 |
Methotrexate guidelines 2009?
Topics: Dermatologic Agents; Humans; Methotrexate; Practice Guidelines as Topic; Psoriasis | 2010 |
Successful treatment of hand and foot psoriasis with infliximab.
Topics: Adult; Antibodies, Monoclonal; Cyclosporine; Dermatologic Agents; DiGeorge Syndrome; Fatty Liver, Alcoholic; Female; Foot Dermatoses; Hand Dermatoses; Hepatitis C, Chronic; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Retinoids; Retrospective Studies; Treatment Outcome | 2010 |
[Guidelines on the use of methotrexate in psoriasis].
Topics: Chemical and Drug Induced Liver Injury; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Records | 2010 |
[Eventration and methotrexate in psoriasis].
Topics: Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer | 2010 |
Benefit-risk analysis of adalimumab versus methotrexate and placebo in the treatment of moderate to severe psoriasis: comparison of adverse event-free response days in the CHAMPION trial.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Placebos; Psoriasis; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Severity of Illness Index; Treatment Outcome | 2010 |
Enhancing percutaneous delivery of methotrexate using different types of surfactants.
Topics: Absorption; Adsorption; Animals; Diffusion; Drug Delivery Systems; Drug Design; Ethylene Glycols; Male; Methotrexate; Psoriasis; Rats; Rats, Wistar; Salicylic Acid; Skin Diseases; Surface-Active Agents; Time Factors | 2011 |
Efficacy of ustekinumab in palmoplantar psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Female; Humans; Male; Methotrexate; Obesity; Psoriasis; Smoking; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Ustekinumab; Vitamin D | 2010 |
Sudden onset of an aggressive cutaneous lymphoma in a young patient with psoriasis: role of immunosuppressants.
Topics: Adult; Antibiotics, Antineoplastic; Biopsy; Cyclosporine; Doxorubicin; Etanercept; Fatal Outcome; Humans; Immunoglobulin G; Immunosuppressive Agents; Leg; Lymphoma, T-Cell, Cutaneous; Male; Methotrexate; Neoplasm Invasiveness; Neoplasm Staging; Polyethylene Glycols; Psoriasis; Receptors, Tumor Necrosis Factor; Skin Neoplasms; Treatment Failure | 2010 |
Treatment of psoriasis in patients with hepatitis C virus infection.
Topics: Acitretin; Antiviral Agents; Cyclosporine; Drug Eruptions; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Methotrexate; Psoriasis; Ribavirin | 2011 |
Nail psoriasis successfully treated with intralesional methotrexate: case report.
Topics: Adult; Dermatologic Agents; Female; Humans; Injections, Intralesional; Methotrexate; Nails; Psoriasis; Treatment Outcome | 2011 |
Effective continuous systemic therapy of severe plaque-type psoriasis is accompanied by amelioration of biomarkers of cardiovascular risk: results of a prospective longitudinal observational study.
Topics: Adalimumab; Adipokines; Adult; Aged; Antibodies, Monoclonal, Humanized; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cyclosporine; Etanercept; Female; Fumarates; Humans; Immunoglobulin G; Longitudinal Studies; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Receptors, Tumor Necrosis Factor; Resistin; Risk Factors; Severity of Illness Index; Treatment Outcome; Vascular Endothelial Growth Factor A | 2011 |
Use of conventional systemic treatments in psoriasis: systematic review and expert opinion of a panel of dermatologists.
Topics: Cyclosporine; Dermatology; Humans; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Retinoids | 2011 |
[Meetings of the Psoriasis Experts: recommendations for daily practice].
Topics: Consensus Development Conferences as Topic; Cyclosporine; Delphi Technique; Evidence-Based Medicine; Expert Testimony; Humans; Methotrexate; Practice Guidelines as Topic; Professional Practice; Psoriasis; Retinoids | 2011 |
Is concomitant use of methotrexate and oral retinoids dangerous? A review of the data regarding this combination.
Topics: Administration, Oral; Dermatologic Agents; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Methotrexate; Pityriasis Rubra Pilaris; Psoriasis; Retinoids | 2011 |
Double trouble: therapeutic challenges in patients with both juvenile dermatomyositis and psoriasis.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Dermatologic Agents; Dermatomyositis; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Methylprednisolone; Mycophenolic Acid; Phototherapy; Prednisone; Psoriasis; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha | 2011 |
Chikungunya infection: a new trigger for psoriasis.
Topics: Adolescent; Adult; Alphavirus Infections; Chikungunya Fever; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Ultraviolet Therapy; Young Adult | 2011 |
Methotrexate or fumarates: which is the best oral treatment for psoriasis?
Topics: Biological Therapy; Dermatologic Agents; Fumarates; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2011 |
Methotrexate intoxication: the Pharmaceutical Care process reveals a critical error.
Topics: Administration, Oral; Aged; Community Pharmacy Services; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Medication Errors; Methotrexate; Pharmacists; Professional Role; Psoriasis; Stomatitis | 2012 |
Patients with moderate to severe plaque psoriasis: one year after the European Medicines Agency recommendation of efalizumab suspension.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Products; Cyclosporine; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Safety-Based Drug Withdrawals; Severity of Illness Index; Treatment Outcome; Withholding Treatment; Young Adult | 2011 |
Infliximab treatment for psoriasis in 120 patients on therapy for a minimum of one year: a review.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Arthritis, Psoriatic; Dermatologic Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2011 |
Ustekinumab treats psoriasis refractory to seven conventional and biologic therapies.
Topics: Acitretin; Adalimumab; Adrenal Cortex Hormones; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Calcitriol; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Tacrolimus; Treatment Outcome; Ustekinumab | 2011 |
Methotrexate and psoriasis: consensus conference.
Topics: Biopsy; Dermatologic Agents; Humans; Liver; Methotrexate; Practice Guidelines as Topic; Psoriasis | 2011 |
Systemic treatment with corticosteroids in psoriasis--health care provision far beyond the S3-guidelines.
Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Cyclosporine; Drug Utilization; Female; Fumarates; General Practice; Germany; Guideline Adherence; Humans; Internal Medicine; Male; Methotrexate; Off-Label Use; Psoriasis; Retinoids | 2011 |
Baseline characteristics and patient reported outcome data of patients prescribed etanercept: web-based and telephone evaluation.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Interviews as Topic; Male; Methotrexate; Middle Aged; Online Systems; Psoriasis; Quality of Life; Receptors, Tumor Necrosis Factor; Self Report; Spondylarthropathies; Telephone; Treatment Outcome | 2011 |
Letter: A case of generalized guttate psoriasis induced by etanercept with relapse after abatacept.
Topics: Abatacept; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Female; Humans; Immunoconjugates; Immunoglobulin G; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Rituximab; Steroids | 2011 |
[Update on psoriasis at the Dermatology Day conference, Paris 2010].
Topics: Comorbidity; Creatinine; Cyclosporine; Dermatologic Agents; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Severity of Illness Index | 2011 |
[News on psoriasis from the 2010 Dermatology Days in Paris].
Topics: Acitretin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Cyclosporine; Dermatologic Agents; Dermatology; Drug Therapy, Combination; Etanercept; Evidence-Based Medicine; Humans; Immunoglobulin G; Methotrexate; Practice Guidelines as Topic; Psoriasis; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Treatment Outcome; Ustekinumab | 2011 |
[Current topics in psoriasis].
Topics: Comorbidity; Dermatologic Agents; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
Rapidly fatal acute ATLL emerging after methotrexate therapy for disseminated psoriasis.
Topics: Dermatologic Agents; Family Health; Fatal Outcome; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Methotrexate; Middle Aged; Psoriasis; Skin; Time Factors | 2012 |
Methotrexate, a drug for the years to come.
Topics: Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis | 2011 |
Superimposed linear psoriasis: low effectiveness of biologic therapy.
Topics: Acitretin; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Biological Therapy; Cyclosporine; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Loss of Heterozygosity; Male; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor | 2011 |
[Multiple warts appearing exclusively on psoriasis plaques].
Topics: Acitretin; Adrenal Cortex Hormones; Alphapapillomavirus; Human papillomavirus 6; Humans; Immunoglobulin A; Immunosuppressive Agents; Keratolytic Agents; Male; Methotrexate; Middle Aged; Papillomavirus Infections; Paraproteinemias; Psoriasis; Remission Induction; Ultraviolet Therapy; Warts | 2011 |
Combination therapy of biologics with traditional agents in psoriasis.
Topics: Anti-Inflammatory Agents; Arthritis, Psoriatic; Dermatologic Agents; Drug Therapy, Combination; Humans; Immunologic Factors; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2011 |
Dermatologist preferences for first-line therapy of moderate to severe psoriasis in healthy adult patients.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Attitude of Health Personnel; Dermatology; Etanercept; Female; Health Care Surveys; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Professional Practice; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Ultraviolet Therapy | 2012 |
Exacerbation of infliximab-induced palmoplantar psoriasis under ustekinumab therapy in a patient with ankylosing spondylitis.
Topics: Acute Disease; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Female; Humans; Infliximab; Methotrexate; Psoriasis; Severity of Illness Index; Spondylitis, Ankylosing; Treatment Failure; Ustekinumab | 2011 |
Liver fibrosis screening for patients with psoriasis taking methotrexate: a cross-sectional study comparing transient elastography and liver biopsy.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cross-Sectional Studies; Dermatologic Agents; Early Diagnosis; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 2012 |
Discontinuation of methotrexate in psoriasis.
Topics: Adult; Aged; Aged, 80 and over; Denmark; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Remission Induction; Time Factors; Treatment Outcome; Young Adult | 2012 |
Treatment of refractory tumor necrosis factor inhibitor-induced palmoplantar pustulosis: a report of 2 cases.
Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Alefacept; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Crohn Disease; Cyclosporine; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Mycophenolic Acid; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Treatment Outcome; Ustekinumab | 2011 |
Acute methotrexate toxicity seen as plaque psoriasis ulceration and necrosis: A diagnostic clue.
Topics: Acute Kidney Injury; Adult; Azithromycin; Biopsy; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Mucositis; Necrosis; Pancytopenia; Plasma; Psoriasis; Recombinant Proteins; Self Medication; Skin Ulcer; Trimethoprim, Sulfamethoxazole Drug Combination | 2011 |
[Choice of therapy based on clinical setting].
Topics: Age Factors; Comorbidity; Contraindications; Cyclosporine; Decision Making; Dermatologic Agents; Female; Hepatic Insufficiency; Humans; Kidney Diseases; Latent Tuberculosis; Mental Disorders; Methotrexate; Pregnancy; Psoriasis; Risk Factors; Skin Neoplasms | 2011 |
[Methotrexate].
Topics: Chemical and Drug Induced Liver Injury; Dermatologic Agents; Drug Interactions; Drug Monitoring; Humans; Lung Diseases; Methotrexate; Pancytopenia; Psoriasis; Skin Neoplasms | 2011 |
[Patient education. Information letter on treatment of psoriasis with methotrexate].
Topics: Anemia; Chemical and Drug Induced Liver Injury; Cough; Dermatologic Agents; Drug Interactions; Fever; Humans; Methotrexate; Nausea; Psoriasis | 2011 |
[Assessment of psoriatic nail lesions therapy by means of nail psoriasis severity index].
Topics: Adult; Aged; Female; Humans; Hyperkeratosis, Epidermolytic; Male; Methotrexate; Middle Aged; Nails, Malformed; Onycholysis; Psoriasis; Treatment Outcome | 2011 |
Association between systemic antipsoriatic drugs and cardiovascular risk in patients with psoriasis with or without psoriatic arthritis: a nationwide cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Psoriatic; Cohort Studies; Comorbidity; Databases, Factual; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Myocardial Ischemia; Psoriasis; Retrospective Studies; Risk; Risk Factors; Taiwan | 2012 |
Estimation of tissue osteopontin levels before and after different traditional therapeutic modalities in psoriatic patients.
Topics: Cyclosporine; Humans; Methotrexate; Osteopontin; Psoriasis; PUVA Therapy | 2013 |
Briakinumab versus methotrexate for psoriasis.
Topics: Antibodies, Monoclonal; Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis | 2012 |
Briakinumab versus Methotrexate for Psoriasis.
Topics: Antibodies, Monoclonal; Dermatologic Agents; Female; Humans; Male; Methotrexate; Psoriasis | 2012 |
Methotrexate reduces the occurrence of cerebrovascular events among Taiwanese psoriatic patients: a nationwide population-based study.
Topics: Asian People; Case-Control Studies; Cerebrovascular Disorders; Chi-Square Distribution; Comorbidity; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Incidence; Male; Methotrexate; Proportional Hazards Models; Psoriasis; Retinoids; Risk Assessment; Risk Factors; Taiwan; Time Factors; Treatment Outcome | 2012 |
Methotrexate toxicity presenting as ulcerated psoriatic plaques.
Topics: Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors; Skin Ulcer; Torso | 2012 |
Differing patterns of methotrexate use for psoriatic disease among dermatologists and rheumatologists.
Topics: Canada; Dermatologic Agents; Dermatology; Humans; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Rheumatology | 2012 |
Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective study.
Topics: Administration, Oral; Adult; Aged; Biomarkers; Chronic Disease; Dermatologic Agents; Erythrocytes; Female; Humans; Male; Medication Adherence; Methotrexate; Middle Aged; Polyglutamic Acid; Prospective Studies; Psoriasis; Treatment Outcome; Young Adult | 2012 |
Physico-chemical characteristics of methotrexate-entrapped oleic acid-containing deformable liposomes for in vitro transepidermal delivery targeting psoriasis treatment.
Topics: Administration, Cutaneous; Animals; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Dermatologic Agents; Diffusion Chambers, Culture; Drug Delivery Systems; Drug Stability; Electrochemistry; Half-Life; In Vitro Techniques; Liposomes; Methotrexate; Oleic Acid; Particle Size; Permeability; Phosphatidylcholines; Phospholipids; Psoriasis; Skin Absorption; Swine | 2012 |
Nail dystrophy in psoriatic arthritis presenting as nail onychomycosis: a case report.
Topics: Arthritis, Psoriatic; Arthrodesis; Chronic Disease; Comorbidity; Finger Joint; Hand Dermatoses; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Nail Diseases; Onychomycosis; Psoriasis; Radiography | 2012 |
Infliximab for the treatment of psoriasis in the U.K.: 9 years' experience of infusion reactions at a single centre.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infliximab; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Young Adult | 2012 |
Nodular melanoma arising in a patient treated with anti-tumor necrosis factor alpha antagonists.
Topics: Acitretin; Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Male; Melanoma; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Skin Neoplasms; Treatment Outcome; Tumor Necrosis Factor-alpha | 2012 |
Response to the letter to editor re: "Methotrexate and psoriasis: consensus conference".
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis | 2012 |
Coexistence of psoriasis and bullous pemphigoid: remission with low-dose methotrexate.
Topics: Adrenal Cortex Hormones; Aged, 80 and over; Dermatologic Agents; Female; Humans; Methotrexate; Pemphigoid, Bullous; Psoriasis; Remission Induction | 2013 |
Methotrexate in psoriasis: do we need to give a test dose?
Topics: Bone Marrow Diseases; Dose-Response Relationship, Drug; Drug Eruptions; Drug Hypersensitivity; Folic Acid; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Methotrexate; Pneumonia; Practice Guidelines as Topic; Psoriasis; Stomatitis, Aphthous | 2012 |
Methotrexate for psoriasiform lesions associated with anti-tumour necrosis factor therapy in inflammatory bowel disease.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Infliximab; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2012 |
Comparative effectiveness of commonly used systemic treatments or phototherapy for moderate to severe plaque psoriasis in the clinical practice setting.
Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Comparative Effectiveness Research; Cross-Sectional Studies; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Quality of Life; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Treatment Outcome; Ultraviolet Therapy; United States; Ustekinumab | 2012 |
Dermatologist preferences for treatments to compare in future randomized controlled comparative effectiveness trials for moderate to severe psoriasis.
Topics: Adalimumab; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Comparative Effectiveness Research; Dermatology; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Ustekinumab | 2012 |
Serum interleukin-6 levels in response to methotrexate treatment in psoriatic patients.
Topics: Adult; Aged; Dermatologic Agents; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Humans; Interleukin-6; Male; Methotrexate; Middle Aged; Psoriasis; Research Design; Treatment Outcome | 2012 |
[Patients with psoriasis have an increased risk of cardiovascular diseases].
Topics: Antirheumatic Agents; Atrial Fibrillation; Cardiovascular Diseases; Denmark; Humans; Immunosuppressive Agents; Methotrexate; Myocardial Infarction; Practice Guidelines as Topic; Psoriasis; Risk Factors; Venous Thromboembolism | 2012 |
Letter: pathogenesis of tumour necrosis factor-alpha antagonists-induced psoriasiform lesions.
Topics: Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2012 |
Methotrexate vs. fumaric acid esters in moderate-to-severe chronic plaque psoriasis: data registry report on the efficacy under daily life conditions.
Topics: Adult; Chronic Disease; Fumarates; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Psoriasis; Registries; Retrospective Studies; Severity of Illness Index | 2013 |
Psoriasis as initiator or amplifier of the systemic inflammatory march: impact on development of severe vascular events and implications for treatment strategy.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Immunosuppressive Agents; Inflammation; Male; Metabolic Diseases; Methotrexate; Middle Aged; Psoriasis; Severity of Illness Index | 2013 |
Understanding the variation in response to methotrexate.
Topics: Erythrocytes; Female; Humans; Male; Medication Adherence; Methotrexate; Polyglutamic Acid; Psoriasis | 2012 |
Oral manifestations of psoriasis. Clinical presentation and management.
Topics: Alefacept; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Carboxymethylcellulose Sodium; Diphenhydramine; Etanercept; Glossitis, Benign Migratory; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Lip Diseases; Methotrexate; Mouth Diseases; Mouth Mucosa; Palliative Care; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins | 2012 |
Unmasking of axial spondyloarthritis and oligoarthritis following discontinuation of tumour necrosis factor inhibitor therapy for psoriasis.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Cyclosporine; Drug Substitution; Humans; Immunosuppressive Agents; Knee Injuries; Male; Methotrexate; Osteoarthritis, Knee; Psoriasis; Spondylarthritis; Tumor Necrosis Factor-alpha; Ustekinumab; Withholding Treatment | 2014 |
Patient-reported reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis.
Topics: Acitretin; Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Cross-Sectional Studies; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Keratolytic Agents; Logistic Models; Male; Methotrexate; Middle Aged; Patient Satisfaction; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Surveys and Questionnaires; Treatment Outcome | 2013 |
Letter: anti-TNFs and psoriasis--friends or foes?
Topics: Anti-Inflammatory Agents; Dermatologic Agents; Female; Humans; Inflammatory Bowel Diseases; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2012 |
Assessment of methotrexate hepatotoxicity in psoriasis patients: a prospective evaluation of four serum fibrosis markers.
Topics: Adult; Aged; Biomarkers; Female; Fibrosis; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 2013 |
Combination of adalimumab with traditional systemic antipsoriatic drugs - a report of 39 cases.
Topics: Acitretin; Adalimumab; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome; Young Adult | 2012 |
Cardiovascular disease event rates in patients with severe psoriasis treated with systemic anti-inflammatory drugs: a Danish real-world cohort study.
Topics: Anti-Inflammatory Agents; Cardiovascular Diseases; Cohort Studies; Confidence Intervals; Denmark; Dermatologic Agents; Female; Humans; Longitudinal Studies; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk Factors; Severity of Illness Index | 2013 |
Arthritis as an important determinant for psoriatic patients to develop severe vascular events in Taiwan: a nation-wide study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis; Cardiovascular Diseases; Cerebrovascular Disorders; Child; Cohort Studies; Comorbidity; Female; Health Surveys; Humans; Incidence; Male; Methotrexate; Middle Aged; Psoriasis; Retinoids; Retrospective Studies; Risk Factors; Taiwan; Young Adult | 2013 |
Methotrexate-induced liver cirrhosis in a patient of psoriasis.
Topics: Aged; Dermatologic Agents; Humans; Liver Cirrhosis; Male; Methotrexate; Psoriasis | 2012 |
Psoriasis and psoriatic arthritis in Peruvian aborigines: a report from the GRAPPA 2011 annual meeting.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Female; Humans; Male; Methotrexate; Middle Aged; Peru; Population Groups; Prevalence; Psoriasis; Retrospective Studies; Severity of Illness Index | 2012 |
[Body-weight changes in psoriatic patients on systemic treatment].
Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Psoriatic; Body Weight; Comorbidity; Dermatologic Agents; Female; Humans; Infliximab; Long-Term Care; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Retrospective Studies; Tumor Necrosis Factor-alpha | 2012 |
Effectiveness of adalimumab dose escalation, combination therapy of adalimumab with methotrexate, or both in patients with psoriasis in daily practice.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Cohort Studies; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Treatment Outcome | 2013 |
Acute mucocutaneous methotrexate toxicity associated with interface dermatitis and numerous eosinophils.
Topics: Aged; Biopsy; Dermatologic Agents; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Humans; Male; Methotrexate; Microscopy, Fluorescence; Mouth Mucosa; Pancytopenia; Predictive Value of Tests; Psoriasis; Skin | 2013 |
Evaluation of risk factors for body weight increment in psoriatic patients on infliximab: a multicentre, cross-sectional study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Diet; Dyslipidemias; Female; Humans; Hypertension; Immunosuppressive Agents; Infliximab; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Retrospective Studies; Risk Factors; Severity of Illness Index; Sex Factors; Smoking; Weight Gain | 2014 |
Association between traditional systemic antipsoriatic drugs and tuberculosis risk in patients with psoriasis with or without psoriatic arthritis: results of a nationwide cohort study from Taiwan.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Female; Glucocorticoids; Humans; Incidence; Male; Methotrexate; Middle Aged; Odds Ratio; Psoriasis; Retrospective Studies; Risk Factors; Taiwan; Tuberculosis | 2013 |
Short-term methotrexate therapy in psoriasis: a study of 197 patients.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dermatologic Agents; Female; Humans; Liver Diseases; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Psoriasis; Retrospective Studies; Severity of Illness Index; Time Factors | 2002 |
Infliximab for the treatment of severe pustular psoriasis.
Topics: Adult; Antibodies, Monoclonal; Dermatologic Agents; Female; Humans; Infliximab; Male; Methotrexate; Psoriasis | 2002 |
[Acute liver failure in a patient with methotrexate therapy].
Topics: Abdomen; Acute Disease; Adult; Dermatologic Agents; Humans; Liver Failure, Acute; Liver Function Tests; Male; Methotrexate; Psoriasis; Ultrasonography | 2002 |
System approach to modeling metabolite formation from parent drug: a working example with methotrexate.
Topics: Administration, Oral; Biological Availability; Biomedical Research; Chemistry, Pharmaceutical; Clinical Trials as Topic; Databases, Factual; Folic Acid Antagonists; Humans; Internet; Linear Models; Methotrexate; Models, Biological; Psoriasis; Software; Time Factors | 2002 |
Effect of low dose weekly methotrexate on bone mineral density and bone turnover.
Topics: Adult; Aged; Aged, 80 and over; Bone Density; Bone Remodeling; Cross-Sectional Studies; Dermatologic Agents; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 2003 |
Cutaneous ulceration with methotrexate.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis; Ulcer | 2003 |
Topical methotrexate delivered by iontophoresis in the treatment of recalcitrant psoriais--a case report.
Topics: Administration, Cutaneous; Dermatologic Agents; Hand Dermatoses; Humans; Iontophoresis; Male; Methotrexate; Middle Aged; Psoriasis | 2003 |
[Psoriasis and systemic lupus erythematosus: a rare association with specific therapeutic problems].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Azathioprine; Dermatologic Agents; Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Psoriasis; Time Factors | 2003 |
[Treatment of severe psoriasis with anti-TNF-alpha-antibody and methotrexate].
Topics: Acrodermatitis; Antibodies, Monoclonal; Dermatologic Agents; Drug Therapy, Combination; Female; Foot Dermatoses; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Tumor Necrosis Factor-alpha | 2003 |
Erythema annulare centrifugum-type psoriasis: a particular variant of acute-eruptive psoriasis.
Topics: Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythema; Female; Follow-Up Studies; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Psoriasis; Recurrence; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2003 |
Psoriasis, vasculitis and methotrexate.
Topics: Adult; Aged; Biopsy, Needle; Disease Progression; Follow-Up Studies; Humans; Immunohistochemistry; Kidney Failure, Chronic; Male; Methotrexate; Psoriasis; Renal Dialysis; Risk Assessment; Severity of Illness Index; Vasculitis | 2003 |
Addition of low-dose methotrexate to infliximab in the treatment of a patient with severe, recalcitrant pustular psoriasis.
Topics: Adjuvants, Immunologic; Aged; Antibodies, Monoclonal; Dermatologic Agents; Drug Therapy, Combination; Humans; Infliximab; Male; Methotrexate; Psoriasis | 2003 |
Cutaneous ulceration caused by methotrexate.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Risk Assessment; Severity of Illness Index; Skin Ulcer | 2003 |
Psoriasis treatment 2003 at the new millennium: position paper on behalf of the authors.
Topics: Dermatologic Agents; Forecasting; History, 20th Century; History, 21st Century; Humans; Managed Care Programs; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Quality of Life | 2003 |
Induction of graft-versus-autoimmune (GVA) disease effect against refractory psoriasis by complete donor-type chimerism and graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Topics: Aged; Cyclosporine; Graft vs Host Disease; Graft vs Tumor Effect; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Methotrexate; Psoriasis; Remission Induction; Time Factors; Transplantation Conditioning; Transplantation, Homologous | 2003 |
Methotrexate vs. aminopterin for psoriasis.
Topics: Aminopterin; Folic Acid Antagonists; Humans; Methotrexate; Psoriasis | 1961 |
Effect of antimetabolites on epidermal structures.
Topics: Antimetabolites; Epidermis; Fluorouracil; Hair; Humans; Mercaptopurine; Methotrexate; Psoriasis; Skin | 1963 |
The use of methotrexate in the treatment of psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1962 |
Psoriasis--chemotherapy with aminopterin and methotrexate.
Topics: Aminopterin; Methotrexate; Psoriasis | 1962 |
A study of the folic acid antagonists in the treatment of psoriasis (aminopterin vs. methotrexate vs. aminopterin and a corticosteroid).
Topics: Adrenal Cortex Hormones; Aminopterin; Folic Acid Antagonists; Humans; Methotrexate; Psoriasis; Triamcinolone | 1963 |
[Psoriasis. treatment by aminopterin and methotrexate].
Topics: Aminopterin; Methotrexate; Psoriasis | 1962 |
Keratoacanthomata in generalized pustular psoriasis.
Topics: Exanthema; Humans; Keratoacanthoma; Methotrexate; Psoriasis; Skin Diseases, Vesiculobullous | 1963 |
The use of folic acid antagonists and steroids in treatment of psoriasis.
Topics: Aminopterin; Folic Acid Antagonists; Humans; Methotrexate; Psoriasis; Steroids; Triamcinolone | 1963 |
METHOTREXATE-INDUCED HEPATIC INJURY IN AN ADULT. A CASE REPORT.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Child; Hepatitis; Humans; Leukemia; Leukopenia; Methotrexate; Pathology; Psoriasis; Toxicology | 1964 |
PARENTERAL METHOTREXATE IN PSORIASIS.
Topics: Cell Division; Child; DNA; Humans; Injections; Injections, Intramuscular; Injections, Intravenous; Metabolism; Methotrexate; Psoriasis; Toxicology | 1964 |
METHOTREXATE IN THE TREATMENT OF PSORIASIS: A CONTROLLED CLINICAL TRIAL.
Topics: Biomedical Research; Methotrexate; Psoriasis; Toxicology | 1963 |
DIAGNOSIS: PSORIASIS AND PSORIATIC ARTHROPATHY TREATED WITH METHOTREXATE ADMINISTERED INTRAVENOUSLY.
Topics: Aminopterin; Arthritis, Psoriatic; Fingers; Humans; Injections, Intravenous; Joint Diseases; Methotrexate; Psoriasis; Steroids; Sunlight; Toes; Toxicology; Triamcinolone; Wrist; Wrist Joint | 1964 |
OBSERVATIONS ON PSORIATIC ARTHRITIS.
Topics: Adrenal Cortex Hormones; Aminopterin; Antimalarials; Arthritis; Arthritis, Psoriatic; Biomedical Research; Diagnosis, Differential; Methotrexate; Psoriasis; Toxicology; Triamcinolone | 1964 |
METHOTREXATE THERAPY IN PSORIATIC ARTHRITIS; DOUBLE-BLIND STUDY ON 21 PATIENTS.
Topics: Alopecia; Arthritis; Arthritis, Psoriatic; Biomedical Research; Double-Blind Method; Drug Eruptions; Drug Therapy; Gastrointestinal Tract; Leukopenia; Liver Diseases; Methotrexate; Psoriasis; Skin; Toxicology; Triamcinolone | 1964 |
METHOTREXATE IN THE MANAGEMENT OF SEVERE PSORIASIS AND ARTHRITIS: REPORT OF A CASE.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Methotrexate; Psoriasis; Toxicology | 1964 |
[ANTIMETABOLITES IN PSORIASIS. PRELIMINARY REPORT].
Topics: Aminopterin; Antimetabolites; Methotrexate; Psoriasis; Toxicology | 1964 |
AMINOPTERIN FOR PSORIASIS. A DECADE'S OBSERVATION.
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Aminopterin; Drug Therapy; Folic Acid; Geriatrics; Humans; Kidney Function Tests; Liver Function Tests; Methionine; Methotrexate; Prednisolone; Pregnancy; Psoriasis; Toxicology; Triamcinolone | 1964 |
PARENTERAL VS. ORAL FOLIC ACID ANTAGONISTS.
Topics: Alanine Transaminase; Aminopterin; Arthritis; Blood Platelets; Drug Therapy; Erythema; Folic Acid Antagonists; Humans; Kidney Function Tests; Leukocyte Count; Leukopenia; Liver Function Tests; Methotrexate; Nausea; Psoriasis; Toxicology | 1964 |
[CYTOSTATIC DRUGS IN THE TREATMENT OF PSORIASIS. WITH SPECIAL REFERENCE TO THE ORAL USE OF AMINOPTERIN].
Topics: Administration, Oral; Aminopterin; Cytostatic Agents; Drug Therapy; Humans; Methotrexate; Psoriasis | 1964 |
THE TREATMENT OF PSORIASIS WITH FOLIC ACID ANTAGONISTS.
Topics: Aminopterin; Blood Cell Count; Bone Marrow Examination; Drug Therapy; Folic Acid Antagonists; Hemoglobinometry; Humans; Intestinal Absorption; Liver Function Tests; Methotrexate; Psoriasis; Toxicology; Xylose | 1964 |
THERAPEUTIC PROGRESS IN DERMATOLOGY.
Topics: Choline; Dermatology; Drug Therapy; Humans; Leukopenia; Methotrexate; Pharmacology; Psoriasis; Urticaria | 1965 |
[REMARKS ON THE USE OF SMALL INTERMITTENT DOSES OF AN ANTIFOLIC AGENT AMETHOPTERIN IN PSORIATIC RHEUMATISM AND OF NITROGEN MUSTARD IN CHRONIC PROTOTYPIC RHEUMATISM (C.E.P.)].
Topics: Arthritis; Arthritis, Rheumatoid; Drug Therapy; Folic Acid Antagonists; Humans; Mechlorethamine; Methotrexate; Psoriasis; Rheumatic Diseases | 1965 |
IMMUNOLOGIC COMPETENCE OF PATIENTS WITH PSORIASIS RECEIVING CYTOTOXIC DRUG THERAPY.
Topics: Allergens; Allergy and Immunology; Aniline Compounds; Antibody Formation; Antigen-Antibody Reactions; Antineoplastic Agents; Azathioprine; Benzene; Catechols; Geriatrics; Humans; Hypersensitivity, Delayed; Immunocompetence; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Pharmacology; Plague Vaccine; Psoriasis; Thioguanine; Triethylenemelamine; Vinblastine | 1965 |
FOLIC-ACID ANTAGONISTS IN TREATMENT OF PSORIASIS.
Topics: Drug Therapy; Duodenal Ulcer; Folic Acid Antagonists; Kidney Diseases; Kidney Tubules; Leukopenia; Melena; Methotrexate; Mouth Diseases; Necrosis; Pathology; Psoriasis; Toxicology | 1965 |
[USE OF FOLIC ACID ANTIMETABOLITES IN TREATMENT OF PSORIASIS].
Topics: Aminopterin; Antimetabolites; Folic Acid; Humans; Methotrexate; Psoriasis | 1965 |
Case studies in severe psoriasis: A clinical strategy.
Topics: Acitretin; Adolescent; Adult; Aged; Algorithms; Dermatologic Agents; Drug Therapy, Combination; Etretinate; Female; Health Surveys; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; Recombinant Fusion Proteins; Severity of Illness Index; Treatment Outcome; Ultraviolet Therapy | 2003 |
Infliximab-induced remission of extensive plaque psoriasis.
Topics: Administration, Oral; Adult; Antibodies, Monoclonal; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infliximab; Injections, Intravenous; Methotrexate; Psoriasis; Remission Induction; Treatment Outcome | 2003 |
Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?
Topics: Adolescent; Adult; Aged; Biopsy; Child; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors; Treatment Outcome | 2004 |
Psoriasis: ten misconceptions.
Topics: Humans; Immunosuppressive Agents; Life Style; Methotrexate; Nails, Malformed; Psoriasis | 2004 |
The canals of hering might represent a target of methotrexate hepatic toxicity.
Topics: Adult; Aged; Female; Humans; Immunosuppressive Agents; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 2004 |
A randomized controlled trial of methotrexate and cyclosporine in the treatment of psoriasis.
Topics: Adolescent; Adult; Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Multicenter Studies as Topic; Netherlands; Psoriasis; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome | 2004 |
Successful treatment of psoriasis and psoriatic arthritis with etanercept and methotrexate in a patient newly unresponsive to infliximab.
Topics: Administration, Oral; Adult; Antibodies, Monoclonal; Arthritis, Psoriatic; Diagnosis, Differential; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Treatment Failure | 2004 |
Interleukin 4 plasma levels in psoriasis vulgaris patients.
Topics: Adult; Anthralin; Female; Ficusin; Humans; Interleukin-4; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; Severity of Illness Index | 2004 |
[Psoriasis in MEDLINE].
Topics: Dermatologic Agents; Evidence-Based Medicine; Humans; Immunosuppressive Agents; MEDLINE; Methotrexate; Patient Participation; Phototherapy; Psoriasis; Retinoids | 2004 |
Methotrexate markedly reduces the expression of vascular E-selectin, cutaneous lymphocyte-associated antigen and the numbers of mononuclear leucocytes in psoriatic skin.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Cell Separation; Dermatologic Agents; Down-Regulation; E-Selectin; Endothelium, Vascular; Flow Cytometry; Humans; Immunohistochemistry; Integrin alpha Chains; Integrin alpha4beta1; Intercellular Adhesion Molecule-1; Leukocytes; Leukocytes, Mononuclear; Lymphocytes; Membrane Glycoproteins; Methotrexate; Perfusion; Psoriasis; Receptors, Interleukin-2; Skin; Superantigens; T-Lymphocytes; Time Factors; Vascular Cell Adhesion Molecule-1 | 2004 |
Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study.
Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Psoriatic; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Immunohistochemistry; Infliximab; Male; Methotrexate; Middle Aged; Neovascularization, Pathologic; Prospective Studies; Psoriasis; Skin; Synovial Membrane; Tumor Necrosis Factor-alpha | 2004 |
Use of infliximab in the treatment of psoriasis.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infliximab; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis; Remission Induction; Time Factors | 2004 |
Excessive drowsiness with low-dose methotrexate.
Topics: Diagnosis, Differential; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Sleep Stages | 2004 |
Analysis of risk factors in psoriatic patients with methotrexate-induced increases in transaminase levels.
Topics: Adult; Age Factors; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Transaminases | 2004 |
Efficacy of concomitant use of PUVA and methotrexate in disease clearance time in plaque type psoriasis.
Topics: Adolescent; Adult; Cohort Studies; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Probability; Psoriasis; PUVA Therapy; Risk Assessment; Sampling Studies; Severity of Illness Index; Treatment Outcome | 2004 |
Systemic therapy does not usually clear psoriasis, but treatment success does not require clearing.
Topics: Acitretin; Cyclosporine; Female; Ficusin; Humans; Immunosuppressive Agents; Keratolytic Agents; Male; Methotrexate; Middle Aged; Patient Satisfaction; Photosensitizing Agents; Psoriasis; PUVA Therapy; Treatment Outcome | 2005 |
Psoriatic uveitis: a distinct clinical entity?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Female; Glucocorticoids; HLA-B27 Antigen; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Uveitis, Anterior | 2005 |
Topical 0.25% methotrexate gel in a hydrogel base for palmoplantar psoriasis.
Topics: Administration, Topical; Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gels; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Severity of Illness Index; Treatment Outcome | 2004 |
Methotrexate toxicity induced by acute renal failure.
Topics: Acute Kidney Injury; Aged; Antirheumatic Agents; Female; Humans; Methotrexate; Psoriasis | 2005 |
Methotrexate for psoriasis: current European practice. A postal survey.
Topics: Biopsy; Blood Cell Count; Data Collection; Drug Administration Schedule; Folic Acid; Humans; Immunosuppressive Agents; Liver; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Surveys and Questionnaires | 2005 |
Traditional systemic treatments have not fully met the needs of psoriasis patients: results from a national survey.
Topics: Acitretin; Adult; Aged; Cyclosporine; Dermatologic Agents; Female; Ficusin; Health Surveys; Humans; Male; Methotrexate; Middle Aged; Patient Satisfaction; Psoriasis; PUVA Therapy; Treatment Outcome; United States | 2005 |
Methotrexate use and monitoring in Switzerland and Denmark.
Topics: Benchmarking; Denmark; Dermatologic Agents; Dermatology; Drug Monitoring; Drug Utilization; Humans; Methotrexate; Practice Patterns, Physicians'; Psoriasis; Surveys and Questionnaires; Switzerland | 2005 |
Noninvasive monitoring for methotrexate hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Dermatologic Agents; Drug Monitoring; Humans; Methotrexate; Psoriasis | 2005 |
Replacement of routine liver biopsy by procollagen III aminopeptide for monitoring patients with psoriasis receiving long-term methotrexate: a multicentre audit and health economic analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Biopsy; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Drug Administration Schedule; Drug Monitoring; Female; Health Care Costs; Humans; Liver Diseases; Male; Medical Audit; Methotrexate; Middle Aged; Patient Satisfaction; Peptide Fragments; Practice Guidelines as Topic; Procollagen; Psoriasis | 2005 |
Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Biopsy; Dermatologic Agents; Drug Monitoring; Female; Humans; Liver; Liver Cirrhosis; Long-Term Care; Male; Methotrexate; Middle Aged; Patient Selection; Peptide Fragments; Practice Guidelines as Topic; Procollagen; Psoriasis; Reproducibility of Results; Severity of Illness Index | 2005 |
Psoriasis-induced postoperative cardiac failure.
Topics: Aged; Dermatitis, Exfoliative; Female; Heart Failure; Humans; Methotrexate; Postoperative Complications; Psoriasis; Vasodilation | 2005 |
[Severe psoriasis: 160 cases].
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Child; Dermatologic Agents; Female; Humans; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Recurrence; Retrospective Studies; Severity of Illness Index; Vitamin D | 2005 |
Severe vertigo requiring hospitalization whilst taking low-dose oral methotrexate for psoriasis.
Topics: Dermatologic Agents; Female; Hospitalization; Humans; Methotrexate; Middle Aged; Psoriasis; Vertigo | 2005 |
Systemic treatment for moderate to severe psoriasis: estimates of failure rates and direct medical costs in a north-eastern US managed care plan.
Topics: Acitretin; Adult; Costs and Cost Analysis; Cyclosporine; Dermatologic Agents; Female; Health Care Costs; Humans; Male; Managed Care Programs; Methotrexate; Middle Aged; New England; Phototherapy; Psoriasis; PUVA Therapy; Treatment Failure; United States | 2005 |
Modern modified 'ultra' Goeckerman therapy: a PASI assessment of a very effective therapy for psoriasis resistant to both prebiologic and biologic therapies.
Topics: Acitretin; Anthralin; Calcitriol; Coal Tar; Combined Modality Therapy; Female; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Nicotinic Acids; Phototherapy; Psoriasis; Salicylic Acid; Severity of Illness Index; Time Factors; Ultraviolet Therapy | 2005 |
Psoriasis Area and Severity Index 50 as an endpoint in psoriasis trials: an unconvincing proposal.
Topics: Alefacept; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Outcome Assessment, Health Care; Psoriasis; Quality of Life; Recombinant Fusion Proteins; Retreatment; Severity of Illness Index | 2005 |
Infliximab for the treatment of psoriasis: clinical experience at the State University of New York at Buffalo.
Topics: Adult; Aged; Antibodies, Monoclonal; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infliximab; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha | 2005 |
The changes in expression of ICAM-3, Ki-67, PCNA, and CD31 in psoriatic lesions before and after methotrexate treatment.
Topics: Adult; Aged; Antigens, CD; Cell Adhesion Molecules; Cell Proliferation; Dermatitis; Dermatologic Agents; Epidermis; Female; Humans; Hyperplasia; Immunohistochemistry; Ki-67 Antigen; Male; Methotrexate; Middle Aged; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Psoriasis | 2005 |
Have methotrexate-induced liver fibrosis and cirrhosis become rare? A matter for reappraisal of routine liver biopsies.
Topics: Alcohol Drinking; Arsenicals; Biomarkers; Biopsy; Dermatologic Agents; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Vitamin A | 2005 |
Precipitation of generalized pustular psoriasis by prednisolone.
Topics: Acute Disease; Anti-Inflammatory Agents; Arthritis; Dermatologic Agents; Drug Eruptions; Female; Humans; Methotrexate; Middle Aged; Prednisolone; Psoriasis; Treatment Outcome | 2006 |
A liver fibrosis cocktail? Psoriasis, methotrexate and genetic hemochromatosis.
Topics: Dermatologic Agents; Fatty Liver; Fibrosis; Hemochromatosis; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2005 |
Infliximab combined with methotrexate as long-term treatment for erythrodermic psoriasis.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Dermatitis, Exfoliative; Dermatologic Agents; Drug Therapy, Combination; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome | 2005 |
Sustained effects of low dose infliximab in combination with methotrexate in the management of chronic recalcitrant psoriasis.
Topics: Adult; Antibodies, Monoclonal; Chronic Disease; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Psoriasis; Tumor Necrosis Factor-alpha | 2005 |
Etanercept monotherapy for a patient with psoriasis, psoriatic arthritis, and concomitant hepatitis C infection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Comorbidity; Etanercept; Hepacivirus; Hepatitis C; Humans; Immunoglobulin G; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Viral Load | 2006 |
Etanercept therapy improves symptoms and allows tapering of other medications in children and adolescents with moderate to severe psoriasis.
Topics: Adolescent; Arthritis, Psoriatic; Child; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Treatment Outcome | 2006 |
Case reports of etanercept in inflammatory dermatoses.
Topics: Adult; Body Surface Area; Dermatomyositis; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Injections, Subcutaneous; Lupus Erythematosus, Cutaneous; Methotrexate; Middle Aged; Pemphigus, Benign Familial; Psoriasis; Quality of Life; Receptors, Tumor Necrosis Factor | 2006 |
Psoriasis treatment in the United States at the end of the 20th century.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Calcitriol; Clobetasol; Dermatologic Agents; Drug Therapy, Combination; Drug Utilization; Female; Health Care Surveys; Humans; Male; Methotrexate; Middle Aged; Office Visits; Psoriasis; Triamcinolone; United States | 2006 |
Use of amino terminal type III procollagen peptide (P3NP) assay in methotrexate therapy for psoriasis.
Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Medical Audit; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 2006 |
Methotrexate and ciclosporin combination for the treatment of severe psoriasis.
Topics: Adult; Aged; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Treatment Outcome | 2006 |
Combination therapy with acitretin for psoriasis.
Topics: Acitretin; Adult; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Keratolytic Agents; Male; Methotrexate; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Severity of Illness Index | 2006 |
Anti-tumor necrosis factor-alpha-induced psoriasis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Prednisone; Psoriasis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2006 |
Folic acid supplementation and methotrexate therapy for psoriasis.
Topics: Dermatologic Agents; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methotrexate; Psoriasis | 2006 |
Effective management of psoriasis symptom worsening during efalizumab therapy without discontinuing treatment: a case study.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Diagnosis, Differential; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intramuscular; Injections, Subcutaneous; Male; Methotrexate; Middle Aged; Psoriasis | 2006 |
Methotrexate: improving safety profile.
Topics: Blood Chemical Analysis; Collagen Type III; Dermatologic Agents; Drug Monitoring; Drug Utilization Review; Electrolytes; Folic Acid; Humans; Liver Function Tests; Methotrexate; Patient Education as Topic; Practice Patterns, Physicians'; Psoriasis; United Kingdom; Urea | 2006 |
Tempting liver fibrosis? Long-term psoriatic methotrexate therapy and heterozygous alpha1-antitrypsin deficiency.
Topics: Aged; alpha 1-Antitrypsin Deficiency; Biopsy; Follow-Up Studies; Humans; Immunosuppressive Agents; Liver Cirrhosis; Male; Methotrexate; Psoriasis; Retrospective Studies; Risk Factors; Time Factors | 2006 |
Liver injury in long-term methotrexate treatment in psoriasis is relatively infrequent.
Topics: Chemical and Drug Induced Liver Injury; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk Factors; Treatment Outcome; Withholding Treatment | 2006 |
The unmet treatment need for moderate to severe psoriasis: results of a survey and chart review.
Topics: Adult; Data Collection; Female; Ficusin; Humans; Male; Methotrexate; Middle Aged; Patient Satisfaction; Photochemotherapy; Psoriasis | 2006 |
Nitric oxide levels in patients with psoriasis treated with methotrexate.
Topics: Adolescent; Adult; Female; Humans; Male; Methotrexate; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Psoriasis | 2006 |
Infliximab- and methotrexate-resistant rebound of psoriasis after discontinuation of efalizumab (Raptiva).
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Drug Resistance; Humans; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence | 2006 |
Psoriasis of the lips: an unusual localization.
Topics: Administration, Oral; Dermatologic Agents; Female; Humans; Lip; Lip Diseases; Methotrexate; Middle Aged; Psoriasis; Treatment Outcome | 2006 |
Adverse events from systemic therapies for psoriasis are common in clinical practice.
Topics: Adult; Aged; Biological Products; Cyclosporine; Dermatologic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Retinoids; Retrospective Studies | 2006 |
Moral and cost dilemma of a psoriasis patient.
Topics: Attitude to Health; Cost of Illness; Dermatologic Agents; Ethics, Clinical; Humans; Liver Cirrhosis, Alcoholic; Male; Methotrexate; Middle Aged; Psoriasis | 2007 |
GRAPPA--Group for Research and Assessment of Psoriasis and Psoriatic Arthritis, Stockholm, May/June 2006.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Humans; International Cooperation; Methotrexate; Practice Guidelines as Topic; Psoriasis; Quality of Health Care; Sweden | 2007 |
Caffeine consumption and methotrexate dosing requirement in psoriasis and psoriatic arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Caffeine; Dermatologic Agents; Drug Interactions; Female; Food-Drug Interactions; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 2007 |
Dermacase. Psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Biopsy, Needle; Drug Therapy, Combination; Female; Humans; Methotrexate; Prognosis; Psoriasis; Risk Assessment; Severity of Illness Index; Vitamin D | 2006 |
The effect of methotrexate on the expression of cell adhesion molecules and activation molecule CD69 in psoriasis.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Biopsy; Cell Adhesion Molecules; Dermatologic Agents; Down-Regulation; Female; Humans; Immunohistochemistry; Lectins, C-Type; Male; Methotrexate; Middle Aged; Phenotype; Psoriasis | 2007 |
Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment.
Topics: Adult; Aged; Alcohols; Dermatologic Agents; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Fibrosis; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2007 |
The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cluster Analysis; Complement Activation; Female; Folic Acid Antagonists; Gene Expression Regulation; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Molecular Sequence Data; Psoriasis; Reverse Transcriptase Polymerase Chain Reaction; Rheumatic Diseases; RNA | 2007 |
Changes in circulating lymphocyte subpopulations following administration of the leucocyte function-associated antigen-3 (LFA-3)/IgG1 fusion protein alefacept.
Topics: Adult; Aged; Alefacept; CD2 Antigens; CD4-Positive T-Lymphocytes; Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Flow Cytometry; Humans; Immunologic Memory; Immunosuppressive Agents; Killer Cells, Natural; Lymphocyte Count; Methotrexate; Middle Aged; Psoriasis; Recombinant Fusion Proteins; Severity of Illness Index; T-Lymphocyte Subsets; Treatment Outcome | 2007 |
Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.
Topics: 5' Untranslated Regions; Adenosine Deaminase; Adult; Folic Acid; Haplotypes; Humans; Hydroxymethyl and Formyl Transferases; Membrane Transport Proteins; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Nucleotide Deaminases; Polymorphism, Genetic; Psoriasis; Purines; Pyrimidines; Reduced Folate Carrier Protein; Thymidylate Synthase | 2007 |
Methotrexate, hyperosmia, and migraine.
Topics: Adult; Comorbidity; Dermatologic Agents; Female; Humans; Methotrexate; Migraine Disorders; Nausea; Olfaction Disorders; Psoriasis | 2006 |
Tissue angiotensin-converting enzyme in patients with various clinical forms of psoriasis.
Topics: Adult; Biomarkers; Biopsy; Case-Control Studies; Dermatologic Agents; Diagnosis, Differential; Female; Gene Expression Regulation, Enzymologic; Humans; Male; Methotrexate; Middle Aged; Peptidyl-Dipeptidase A; Photochemotherapy; Psoriasis; Skin | 2007 |
Biochemical and biophysical assessment of MTX-induced liver fibrosis in psoriasis patients: Fibrotest predicts the presence and Fibroscan predicts the absence of significant liver fibrosis.
Topics: Adult; Aged; Algorithms; Artificial Intelligence; Biopsy; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Ultrasonography | 2007 |
Methotrexate and risk for lymphoma.
Topics: Dermatologic Agents; Homocysteine; Humans; Lymphoma; Methotrexate; Psoriasis; Risk Factors | 2007 |
A simple intervention to improve safety in methotrexate prescribing.
Topics: Clinical Protocols; Dermatologic Agents; Drug Monitoring; Humans; Methotrexate; Organizational Innovation; Practice Patterns, Physicians'; Psoriasis; Safety Management; United Kingdom | 2007 |
Patients with moderate-to-severe plaque psoriasis preferred oral therapies to phototherapies: a preference assessment based on clinical scenarios with trade-off questions.
Topics: Acitretin; Administration, Oral; Adult; Cyclosporine; Dermatologic Agents; Female; Humans; Keratolytic Agents; Male; Methotrexate; Patient Satisfaction; Psoriasis; PUVA Therapy; Surveys and Questionnaires; Treatment Outcome; Ultraviolet Therapy | 2007 |
Folate with methotrexate: big benefit, questionable cost.
Topics: Costs and Cost Analysis; Dermatologic Agents; Drug Interactions; Folic Acid; Humans; Methotrexate; Psoriasis; Severity of Illness Index | 2007 |
Dermatologists' adherence to the guideline of the Dutch Society of Dermatology and Venereology with respect to the treatment with methotrexate for severe chronic plaque psoriasis: results from a Dutch survey.
Topics: Adult; Dermatology; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Guideline Adherence; Health Care Surveys; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Netherlands; Practice Guidelines as Topic; Psoriasis; Quality of Health Care; Severity of Illness Index; Societies, Medical; Surveys and Questionnaires | 2007 |
Disseminated molluscum contagiosum in a patient with chronic plaque psoriasis taking methotrexate.
Topics: Aged; Cryotherapy; Humans; Immunosuppressive Agents; Male; Methotrexate; Molluscum Contagiosum; Psoriasis; Treatment Outcome | 2007 |
Conventional therapies for psoriasis.
Topics: Acitretin; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Humans; Italy; Keratolytic Agents; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic; Treatment Outcome | 2007 |
Disseminated cryptococcal infection in a patient with severe psoriasis treated with efalizumab, methotrexate and ciclosporin.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cryptococcosis; Cryptococcus neoformans; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Methotrexate; Psoriasis | 2007 |
Pulmonary lymphoma developed during long-term methotrexate therapy for psoriasis.
Topics: Adult; Humans; Immunosuppressive Agents; Lung; Lung Neoplasms; Lymphoma; Male; Methotrexate; Prognosis; Psoriasis; Tomography, X-Ray Computed | 2007 |
Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes.
Topics: Administration, Cutaneous; Chemistry, Pharmaceutical; Dermatologic Agents; Diffusion Chambers, Culture; Drug Compounding; Drug Stability; Ethanol; Humans; Liposomes; Methotrexate; Particle Size; Permeability; Phospholipids; Psoriasis; Skin; Skin Absorption; Solubility; Solvents; Surface Properties; Time Factors | 2007 |
[Therapeutic strategies against psoriasis. Skin to hide -- and how do you free your patients from it].
Topics: Adrenal Cortex Hormones; Anthralin; Arthritis, Psoriatic; Biological Products; Cyclosporine; Dermatologic Agents; Female; Fumarates; Humans; Male; Methotrexate; Phototherapy; Psoriasis; PUVA Therapy; Retinoids; Sex Factors | 2007 |
[Serum liver tests in patients treated with methotrexate. A retrospective analysis].
Topics: Acute Disease; Biomarkers; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Psoriasis; Retrospective Studies; Transaminases | 2007 |
Bilateral periocular psoriasis: an initial manifestation of acute generalized pustular psoriasis with coexistent Sjögren's syndrome.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Adult; Betamethasone; Drug Therapy, Combination; Eyelid Diseases; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrexate; Orbital Diseases; Prednisolone; Psoriasis; Sjogren's Syndrome | 2007 |
Anti-tumour necrosis factor-alpha therapy increases body weight in patients with chronic plaque psoriasis: a retrospective cohort study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Body Mass Index; Chronic Disease; Cohort Studies; Etanercept; Female; Homeostasis; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Retrospective Studies; Tumor Necrosis Factor-alpha; Weight Gain | 2008 |
Reliability of the Roenigk classification of liver damage after methotrexate treatment for psoriasis: a clinicopathologic study of 160 liver biopsy specimens.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Psoriasis; Reproducibility of Results; Retrospective Studies; Severity of Illness Index; Single-Blind Method | 2007 |
Methotrexate-induced papular eruption following treatment of psoriasis.
Topics: Drug Eruptions; Female; Humans; Immunosuppressive Agents; Injections, Intramuscular; Methotrexate; Middle Aged; Pruritus; Psoriasis; Skin; Skin Diseases | 2008 |
Acantholytic dermatosis in psoriatic patient with methotrexate toxicity.
Topics: Acantholysis; Aged; Female; Humans; Immunosuppressive Agents; Methotrexate; Psoriasis | 2008 |
Etanercept therapy allows the tapering of methotrexate and sustained clinical responses in patients with moderate to severe psoriasis.
Topics: Adult; Dermatologic Agents; Drug Administration Schedule; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor | 2008 |
[Management of severe psoriasis: about 50 cases].
Topics: Acitretin; Adolescent; Adult; Aged; Arthritis, Psoriatic; Child; Dermatitis, Exfoliative; Female; Follow-Up Studies; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Quality of Life; Retinoids; Retrospective Studies; Treatment Outcome | 2007 |
Methotrexate: prescribing and monitoring practices among the consultant membership of the British Association of Dermatologists.
Topics: Abortifacient Agents, Nonsteroidal; Dermatology; Drug Administration Routes; Drug Monitoring; Humans; Methotrexate; Physicians; Practice Guidelines as Topic; Professional Practice; Psoriasis; Risk Factors; Surveys and Questionnaires | 2008 |
Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis.
Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Child; Child, Preschool; Dermatologic Agents; Female; Gene Frequency; Haplotypes; Humans; Infant; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Polymorphism, Single Nucleotide; Psoriasis; Receptor, Adenosine A1; Receptor, Adenosine A2A; Retrospective Studies; Treatment Outcome | 2008 |
Concurrent use of methotrexate and acitretin revisited.
Topics: Acitretin; Adolescent; Adult; Aged; Alcohol Drinking; Alopecia; Chemical and Drug Induced Liver Injury; Child; Contraindications; Dermatologic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome | 2008 |
Isolated sixth nerve palsy following low dose oral methotrexate.
Topics: Abducens Nerve Diseases; Dermatologic Agents; Female; Humans; Methotrexate; Middle Aged; Psoriasis | 2007 |
Effect of anti-tumor necrosis factor-alpha therapies on body mass index in patients with psoriasis.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Body Mass Index; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Retrospective Studies; Tumor Necrosis Factor-alpha; Weight Gain | 2008 |
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.
Topics: Acitretin; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Cardiovascular Diseases; Cyclosporine; Depression; Etanercept; Humans; Immunoglobulin G; Interleukin-12; Interleukin-23; Lymphoma; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Smoking; Tumor Necrosis Factor-alpha | 2008 |
Adalimumab may be better or no worse than methotrexate in the treatment of psoriasis.
Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dermatologic Agents; Drug Administration Routes; Humans; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic | 2008 |
The treatment of psoriasis with methotrexate.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Alopecia; Anemia, Macrocytic; Aspartate Aminotransferases; Diarrhea; Dyspepsia; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nucleotidases; Psoriasis; Stomatitis; Sulfobromophthalein | 1967 |
Psoriasis and folic acid antagonists.
Topics: Humans; Methotrexate; Psoriasis; Uremia | 1967 |
Morphologic changes induced by methotrexate. Histologic studies of normal and psoriatic epidermis.
Topics: Adult; Basement Membrane; Biopsy; Cell Division; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Psoriasis; Skin | 1967 |
An anti-cancer drug used in psoriasis.
Topics: Dermatologic Agents; Humans; Methotrexate; Pharmacy; Psoriasis; Self Medication | 1967 |
Methotrexate in the treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Humans; Methotrexate; Middle Aged; Psoriasis | 1967 |
Antitumor drugs in diseases of the skin.
Topics: Antimetabolites; Humans; Methotrexate; Mycosis Fungoides; Nucleosides; Psoriasis | 1967 |
Methotrexate in psoriasis. Precipitation of gout.
Topics: Colchicine; Female; Gout; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis; Uric Acid | 1967 |
Topical methotrexate in psoriasis.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1967 |
Histopathology and histochemistry of psoriasis. II. Dynamics of lesions during treatment.
Topics: Capillaries; Coal Tar; Histocytochemistry; Humans; Injections, Intravenous; Methotrexate; Mitosis; Occlusive Dressings; Ointments; Oxidoreductases; Psoriasis; Triamcinolone Acetonide; Ultraviolet Therapy | 1967 |
Methotrexate for psoriasis.
Topics: Abnormalities, Drug-Induced; Chemical and Drug Induced Liver Injury; Female; Humans; Leukemia; Methotrexate; Peptic Ulcer; Pregnancy; Pregnancy Complications; Psoriasis | 1967 |
Psoriasis before and after methotrexate (MXT) treatment. 1. The Golgi apparatus and phosphatases.
Topics: Adolescent; Adult; Golgi Apparatus; Humans; Methotrexate; Middle Aged; Phosphoric Monoester Hydrolases; Psoriasis | 1984 |
Synergistic carcinogenic potential of methotrexate and PUVA in psoriasis.
Topics: Adult; Cocarcinogenesis; Humans; Male; Methotrexate; Photochemotherapy; Psoriasis; PUVA Therapy; Skin Neoplasms | 1983 |
Methotrexate in lieu of razoxane for incapacitating psoriasis.
Topics: Humans; Leukemia, Myeloid, Acute; Methotrexate; Piperazines; Psoriasis; Razoxane; Skin Neoplasms | 1984 |
Methotrexate, psoriasis, and malignancy.
Topics: Adult; Aged; Bone Marrow; Chromosome Aberrations; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
HLA antigens in methotrexate-induced liver cirrhosis.
Topics: Epitopes; HLA Antigens; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1980 |
Immunoglobulin-bearing cells in the liver biopsies from patients with psoriasis.
Topics: Adolescent; Adult; Aged; Female; Humans; Immunoglobulins; Liver; Liver Diseases; Male; Methotrexate; Microscopy, Fluorescence; Middle Aged; Psoriasis | 1980 |
Razoxane in the treatment of psoriatic patients resistant to or intolerant of PUVA, methotrexate and etretinate.
Topics: Adult; Aged; Drug Resistance; Etretinate; Female; Humans; Male; Methotrexate; Middle Aged; Piperazines; Psoriasis; PUVA Therapy; Razoxane | 1982 |
Galactose tolerance test and methotrexate-induced liver fibrosis and cirrhosis in patients with psoriasis.
Topics: Administration, Oral; Biopsy; Drug Tolerance; Galactose; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1982 |
Methotrexate in psoriatic arthritis: a retrospective study.
Topics: Adolescent; Adult; Aged; Arthritis; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1983 |
Skin carcinomas and treatment with photochemotherapy (PUVA).
Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasms, Radiation-Induced; Photochemotherapy; Psoriasis; PUVA Therapy; Radiation Dosage; Risk; Skin Neoplasms | 1983 |
Psoriasis pustulosa treated with methotrexate and leucovorin.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Psoriasis | 1983 |
Methotrexate.
Topics: Abnormalities, Drug-Induced; Arthritis; Arthritis, Rheumatoid; Drug Interactions; Humans; Infant, Newborn; Methotrexate; Myositis; Neoplasms; Psoriasis; Rheumatic Diseases | 1984 |
Methotrexate for psoriasis. By Henry H. Roenigk, Jr., John R. Haserick, and George H. Curtis.
Topics: Adolescent; Adult; Aged; Dermatology; Female; History, 19th Century; Humans; Male; Methotrexate; Middle Aged; Psoriasis; United States | 1983 |
Treatment of psoriasis.
Topics: Humans; Methotrexate; Psoriasis; PUVA Therapy; Triamcinolone Acetonide; Ultraviolet Therapy | 1984 |
Cytotoxic drugs for non-neoplastic disease.
Topics: Fractures, Spontaneous; Humans; Male; Methotrexate; Middle Aged; Osteoporosis; Psoriasis | 1983 |
[Multiple primary malignant melanomas in psoriasis vulgaris under long-term methotrexate therapy].
Topics: Dose-Response Relationship, Drug; Humans; Long-Term Care; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Psoriasis; Skin Neoplasms | 1984 |
Successful psoriasis treatment then sudden 'cytotoxicity'.
Topics: Adult; Agranulocytosis; Drug Interactions; Gingivitis, Necrotizing Ulcerative; Humans; Male; Methotrexate; Pneumonia, Mycoplasma; Psoriasis; Tetracycline | 1984 |
Psoriasis before and after methotrexate (MXT) treatment. 3. Localization of dopa oxidase.
Topics: Catechol Oxidase; Humans; Methotrexate; Monophenol Monooxygenase; Psoriasis | 1984 |
Psoriasis: utilising the treatment options.
Topics: Adrenal Cortex Hormones; Dermatitis, Exfoliative; Facial Dermatoses; Furocoumarins; Humans; Methotrexate; Nail Diseases; Photochemotherapy; Psoriasis; Scalp Dermatoses; Ultraviolet Therapy | 1980 |
Familial juvenile generalized pustular psoriasis.
Topics: Acrodermatitis; Adolescent; Adult; Chronic Disease; Female; HLA Antigens; Humans; Impetigo; Male; Methotrexate; Pedigree; Psoriasis | 1984 |
Methotrexate and etretinate in the treatment of psoriasis.
Topics: Drug Therapy, Combination; Etretinate; Female; Humans; Methotrexate; Middle Aged; Psoriasis | 1984 |
Two patterns of skin ulceration induced by methotrexate in patients with psoriasis.
Topics: Adult; Aged; Biopsy; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Skin; Skin Ulcer; Time Factors | 1984 |
Sister chromatid exchange in patients treated with methotrexate for psoriasis.
Topics: Adult; Aged; Female; Humans; Lymphocytes; Male; Methotrexate; Middle Aged; Psoriasis; Sister Chromatid Exchange; Time Factors | 1984 |
Pharmacokinetics of methotrexate in erythrocytes in psoriasis.
Topics: Adult; Aged; Erythrocytes; Female; Folic Acid; Humans; Kinetics; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
Improvement of the efficacy and safety of oral methoxsalen photochemotherapy.
Topics: Administration, Oral; Adrenal Cortex Hormones; Anthralin; Drug Therapy, Combination; Humans; Methotrexate; Photochemotherapy; Psoriasis; PUVA Therapy; Retinoids; Tars | 1984 |
Cytostatic agents.
Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Methotrexate; Psoriasis | 1984 |
Concurrent methotrexate and etretinate therapy for psoriasis.
Topics: Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Tretinoin | 1983 |
Toxic hepatitis due to combination therapy with methotrexate and etretinate in psoriasis.
Topics: Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Tretinoin | 1983 |
Risk of carcinogenicity in patients with psoriasis treated with methotrexate or PUVA singly or in combination.
Topics: Humans; Methotrexate; Neoplasms, Radiation-Induced; Photochemotherapy; Psoriasis; PUVA Therapy; Risk; Skin Neoplasms | 1983 |
Commentary and update: methotrexate for psoriasis--two decades later.
Topics: Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Humans; Liver; Methotrexate; Psoriasis; PUVA Therapy; Retinoids | 1983 |
Frequency of malignant neoplasms in 248 long-term methotrexate-treated psoriatics. A preliminary study.
Topics: Administration, Oral; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Risk; Time Factors | 1983 |
Psoriasis before and after methotrexate (MXT) treatment: II. Localization of mitochondria and dehydrogenases.
Topics: Adolescent; Adult; Humans; L-Lactate Dehydrogenase; Methotrexate; Middle Aged; Mitochondria; Psoriasis; Skin; Succinate Dehydrogenase | 1983 |
[Porphyria cutanea tarda caused by methotrexate and buthiopurine therapy].
Topics: Aged; Antineoplastic Agents; Drug Therapy, Combination; Humans; Liver; Male; Mercaptopurine; Methotrexate; Porphyrias; Psoriasis | 1983 |
Methotrexate and etretinate as concurrent therapies in the treatment of psoriasis.
Topics: Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Etretinate; Female; Humans; Methotrexate; Middle Aged; Psoriasis | 1984 |
Low-dose methotrexate kinetics in arthritis.
Topics: Absorption; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
Treatment modalities of psoriatics over a 6-year period (1975-1981).
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Combined Modality Therapy; Etretinate; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy | 1984 |
Treatment of generalized pustular psoriasis with etretinate (Ro 10-9359) and methotrexate.
Topics: Acute Disease; Chronic Disease; Drug Administration Schedule; Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
Entero-hepatic cycling of methotrexate estimated by use of the D-isomer as a reference marker.
Topics: Administration, Oral; Adolescent; Adult; Enterohepatic Circulation; Female; Humans; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Methotrexate; Middle Aged; Models, Biological; Psoriasis; Stereoisomerism | 1984 |
Nonlinear renal elimination kinetics of methotrexate due to saturation of renal tubular reabsorption.
Topics: Absorption; Adult; Aged; Female; Humans; Kidney Tubules; Kinetics; Male; Methotrexate; Middle Aged; Psoriasis | 1984 |
Toxic megacolon associated with methotrexate therapy.
Topics: Colitis, Ulcerative; Colon; Female; Humans; Megacolon, Toxic; Methotrexate; Middle Aged; Psoriasis | 1984 |
[Therapy of psoriasis].
Topics: Anthralin; Etretinate; Humans; Methotrexate; Psoriasis; PUVA Therapy; Salicylates | 1983 |
Recent advances in the treatment of psoriasis.
Topics: Anthralin; Coal Tar; Drug Therapy, Combination; Etretinate; Humans; Methotrexate; Psoriasis; PUVA Therapy; Razoxane; Tretinoin; Ultraviolet Therapy | 1983 |
Methotrexate inhibits polymorphonuclear leucocyte chemotaxis in psoriasis.
Topics: Adult; Aged; Chemotaxis, Leukocyte; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Neutrophils; Psoriasis | 1983 |
Assessment of liver function using fasting bile salt concentrations in psoriasis prior to and during methotrexate therapy.
Topics: Adult; Aged; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Fasting; Female; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1983 |
Current trends in the treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Anthralin; Drug Therapy, Combination; Etretinate; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Time Factors; Tretinoin | 1983 |
[Comparison of RePUVA and aromatic retinoid Ro 10-9359 with methotrexate in severe forms of psoriasis].
Topics: Drug Resistance; Drug Therapy, Combination; Etretinate; Humans; Methotrexate; Methoxsalen; Photochemotherapy; Psoriasis; PUVA Therapy; Tretinoin | 1983 |
Methotrexate-induced necrolysis.
Topics: Aged; Female; Humans; Methotrexate; Psoriasis; Stevens-Johnson Syndrome | 1983 |
Inhibition of a Langerhans cell-mediated immune response by treatment modalities useful in psoriasis.
Topics: Anthralin; Cell Survival; Epidermal Cells; Hot Temperature; Humans; Hydrocortisone; In Vitro Techniques; Langerhans Cells; Methotrexate; Neutrophils; Psoriasis | 1983 |
[Therapy of psoriasis with methotrexate].
Topics: Humans; Methotrexate; Psoriasis | 1983 |
Psoriasis.
Topics: Anthralin; Furocoumarins; Humans; Methotrexate; Photochemotherapy; Psoriasis; United States | 1980 |
Treatment of psoriasis with methotrexate and folinic acid.
Topics: Drug Combinations; Humans; Leucovorin; Methotrexate; Psoriasis | 1980 |
Cutaneous pathobiology mediated by chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Autoradiography; Bone Neoplasms; Epidermis; Female; Humans; Methotrexate; Middle Aged; Osteosarcoma; Psoriasis; Purpura; Skin; Skin Diseases, Vesiculobullous | 1980 |
Methotrexate and ultraviolet radiation.
Topics: Adult; Arthritis; Coal Tar; Female; Humans; Methotrexate; Psoriasis; Recurrence; Sunburn; Ultraviolet Therapy | 1982 |
Etretinate therapy improves psoriasis but elevates serum lipids.
Topics: Adult; Aged; Cholesterol; Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Tretinoin; Triglycerides | 1982 |
Methotrexate maintenance following Ingram therapy in 'difficult' psoriasis.
Topics: Anthralin; Coal Tar; Female; Humans; Male; Methotrexate; Psoriasis; Retrospective Studies; Ultraviolet Therapy | 1982 |
Combined methotrexate-PUVA therapy in the treatment of psoriasis.
Topics: Adult; Aged; Humans; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
Methotrexate used for psoriasis and the risk of noncutaneous or cutaneous malignancy.
Topics: Adult; Cocarcinogenesis; Follow-Up Studies; Humans; Medical History Taking; Methotrexate; Middle Aged; Psoriasis; Risk; Skin Neoplasms | 1982 |
[Treatment of pustulous and erythrodermic psoriasis with PUVA therapy and methotrexate].
Topics: Humans; Methotrexate; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
Liver biopsies upsilon liver scans in methotrexate-treated patients with psoriasis.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Radionuclide Imaging; Retrospective Studies | 1982 |
Methotrexate and etretinate as concurrent therapies in severe psoriasis.
Topics: Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Tretinoin | 1982 |
Complications in methotrexate treatment of psoriasis with particular reference to liver fibrosis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1982 |
Treatment of chronic psoriasis vulgaris.
Topics: Adrenal Cortex Hormones; Anthralin; Coal Tar; Humans; Methotrexate; Peritoneal Dialysis; Psoriasis; PUVA Therapy; Vitamin A | 1982 |
Methotrexate dosage schedule.
Topics: Humans; Methotrexate; Psoriasis | 1982 |
The management of psoriasis.
Topics: Anthralin; Humans; Methotrexate; Psoriasis; PUVA Therapy; Steroids, Fluorinated; Tars; Ultraviolet Therapy | 1982 |
Increased rate of opsonization of zymosan by serum from patients with psoriasis.
Topics: Humans; Methotrexate; Neutrophils; Opsonin Proteins; Oxygen Consumption; Phagocytosis; Psoriasis; Zymosan | 1982 |
[Persistent psoriasis: failure of PUVA and peritoneal dialysis-response to methotrexate and hydroxyurea].
Topics: Aged; Female; Humans; Hydroxyurea; Methotrexate; Peritoneal Dialysis; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
Intestinal function and methotrexate absorption in psoriatic patients.
Topics: Adult; Aged; Female; Humans; Intestinal Absorption; Intestines; Male; Methotrexate; Middle Aged; Psoriasis; Xylose | 1982 |
Combined methotrexate--ultraviolet B therapy in the treatment of psoriasis.
Topics: Adult; Erythema; Fatigue; Female; Humans; Male; Methotrexate; Middle Aged; Nausea; Photochemotherapy; Psoriasis; PUVA Therapy | 1982 |
[Combined treatment of severe forms of psoriasis using aromatic retinoid].
Topics: Drug Evaluation; Drug Therapy, Combination; Etretinate; Female; Humans; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Time Factors; Tretinoin | 1982 |
[Prospects for psoriatic patients treated with methotrexate (author's transl)].
Topics: Adult; Aged; Humans; Methotrexate; Middle Aged; Psoriasis | 1981 |
Erythema resulting from suberythemogenic doses of ultraviolet radiation and methotrexate.
Topics: DNA Repair; Erythema; Humans; Male; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; PUVA Therapy; Skin; Time Factors; Ultraviolet Therapy | 1981 |
Methotrexate for psoriasis: 1981.
Topics: Drug Administration Schedule; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1981 |
Investigations into sister chromatid exchange in patients under cytostatic therapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Child; Child, Preschool; Crossing Over, Genetic; Cyclophosphamide; DNA Repair; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infant; Lung Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis; Sister Chromatid Exchange | 1981 |
Immunological features of psoriasis. Effects of Ro-109359, concanavalin A, pokeweed mitogen, and methotrexate on cultivated lymphocytes.
Topics: Antibody Formation; Concanavalin A; Etretinate; Humans; Immunoglobulin G; Immunoglobulin M; Lymphocyte Activation; Lymphocytes; Methotrexate; Pokeweed Mitogens; Psoriasis; Tretinoin | 1981 |
Treatment of generalized pustular psoriasis with methotrexate and colchicine.
Topics: Adult; Colchicine; Female; Humans; Methotrexate; Psoriasis; Suppuration | 1981 |
Psoriasis, methotrexate, and oligospermia.
Topics: Adult; Humans; Male; Methotrexate; Oligospermia; Psoriasis; Testis | 1980 |
From the NIH: a look at the management of psoriasis.
Topics: Furocoumarins; Humans; Methotrexate; Photochemotherapy; Psoriasis; Skin Neoplasms; Ultraviolet Therapy | 1980 |
Methotrexate in psoriasis. A brief review of indications, usage, and complications of methotrexate therapy.
Topics: Acute Kidney Injury; Humans; Liver Cirrhosis; Methotrexate; Pneumonia; Psoriasis | 1980 |
Methotrexate hepatotoxicity in psoriasis. Consideration of liver biopsies at regular intervals.
Topics: Adult; Age Factors; Aged; Bile Ducts; Biopsy; Female; Hematoma; Humans; Liver; Liver Diseases; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors | 1980 |
Methotrexate induced liver cirrhosis. Studies including serial liver biopsies during continued treatment.
Topics: Adult; Aged; Alcohol Drinking; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1980 |
[Multiple superficial skin basalioma in a patient with psoriasis].
Topics: Arsenic; Carcinoma, Basal Cell; Drug Therapy, Combination; Humans; Male; Methotrexate; Neoplasms, Multiple Primary; Psoriasis; Skin Neoplasms | 1980 |
Liver biopsies in patients on methotrexate for the treatment of psoriasis.
Topics: Biopsy, Needle; Chemical and Drug Induced Liver Injury; Humans; Liver; Methotrexate; Psoriasis | 1980 |
Liver biopsies in psoriatics--complications and evaluation.
Topics: Adult; Aged; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Pneumothorax; Psoriasis | 1980 |
[Change in the coagulating and anticoagulating systems in psoriasis treated with methotrexate].
Topics: Adult; Blood Coagulation; Fibrinolysis; Hemostasis; Humans; Methotrexate; Middle Aged; Psoriasis | 1980 |
[Methotrexate-induced liver cirrhosis in psoriasis. Determination of tissue type and histopathological assessment].
Topics: Adult; Aged; Female; HLA Antigens; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1980 |
Razoxane in the treatment of psoriasis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Piperazines; Psoriasis; Razoxane | 1980 |
Elevated numbers of proliferating mononuclear cells in the peripheral blood of psoriatic patients correlate with disease severity.
Topics: Cell Division; HLA-DR Antigens; Humans; Leukocyte Count; Leukocytes, Mononuclear; Methotrexate; Phenotype; Psoriasis | 1995 |
Abnormalities of serum type III procollagen aminoterminal peptide in methotrexate-treated psoriatic patients with normal liver histology do not correlate with hepatic ultrastructural changes.
Topics: Adult; Aged; Biomarkers; Dermatologic Agents; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1995 |
Increased spontaneous production of IL-8 in peripheral blood monocytes from the psoriatic patient: relation to focal infection and response to treatments.
Topics: Adolescent; Adult; Aged; Female; Humans; Interleukin-8; Male; Methotrexate; Middle Aged; Monocytes; Palatine Tonsil; Physical Stimulation; Psoriasis; Severity of Illness Index; Time Factors; Tonsillectomy | 1995 |
[The effect of methotrexate on activity of T-lymphocyte marker enzymes in patients with psoriasis vulgaris].
Topics: Adenosine Deaminase; Humans; Methotrexate; Psoriasis; Purine-Nucleoside Phosphorylase; T-Lymphocytes | 1995 |
Uveitis in patients with generalized pustular psoriasis.
Topics: Adult; Humans; Male; Methotrexate; Psoriasis; Uveitis | 1995 |
Liver fibrosis quantified by image analysis in methotrexate-treated patients with psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Image Processing, Computer-Assisted; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Staining and Labeling; Statistics as Topic | 1993 |
Methotrexate in the treatment of psoriasis at the National Skin Centre, Singapore.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Biopsy; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Singapore; Time Factors; Treatment Outcome; Ultraviolet Therapy | 1994 |
Assessing the preferences of patients with psoriasis. A quantitative, utility approach.
Topics: Adult; Aged; Attitude to Health; Biopsy; Chemical and Drug Induced Liver Injury; Decision Making; Female; Forecasting; Health Status; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Patient Satisfaction; Psoriasis; Quality of Life; Time Factors; Treatment Outcome | 1995 |
Recurrent gonarthritis in a patient with palmoplantar pustulosis.
Topics: Adrenal Cortex Hormones; Adult; Humans; Male; Methotrexate; Osteoarthritis; Psoriasis | 1995 |
Methotrexate for chronic diseases in adults.
Topics: Adult; Arthritis, Rheumatoid; Chronic Disease; Drug Monitoring; Humans; Methotrexate; Psoriasis | 1995 |
[Psoriasis: diagnosis and therapy].
Topics: Combined Modality Therapy; Cyclosporine; Dermatologic Agents; Humans; Methotrexate; Psoriasis; Psychotherapy; PUVA Therapy; Retinoids | 1995 |
Treatment of psoriasis.
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1995 |
A case of infantile febrile psoriasiform dermatitis.
Topics: Dermatitis; Diagnosis, Differential; Epidermis; Humans; Infant; Keratinocytes; Lichenoid Eruptions; Lymphocytosis; Male; Methotrexate; Necrosis; Periodicity; Psoriasis; Skin; Staphylococcus aureus; Transaminases | 1995 |
Ultrasound imaging of psoriatic skin: a noninvasive technique to evaluate treatment of psoriasis.
Topics: Adult; Aged; Cell Division; Cyclosporine; Drug Combinations; Epidermis; Female; Follow-Up Studies; Glucosamine; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Skin; Sulfasalazine; Ultrasonography | 1994 |
Short term methotrexate therapy in psoriasis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 1994 |
Methotrexate therapy of psoriasis: differential sensitivity of proliferating lymphoid and epithelial cells to the cytotoxic and growth-inhibitory effects of methotrexate.
Topics: Cell Division; Cell Survival; Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; HeLa Cells; Humans; Keratinocytes; Lymphoid Tissue; Macrophages; Methotrexate; Psoriasis; Skin | 1995 |
The value of a baseline liver biopsy prior to methotrexate treatment.
Topics: Adult; Biopsy; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Patient Selection; Psoriasis | 1994 |
PUVA and methotrexate therapy of psoriasis: how closely do dermatology departments follow treatment guidelines? Psoriasis Audit Workgroup of the British Association of Dermatologists.
Topics: Clinical Protocols; Dermatology; Female; Hospital Departments; Humans; Medical Audit; Methotrexate; Psoriasis; PUVA Therapy | 1994 |
Reactivation of phototoxicity test for psoralens plus ultraviolet A by low-dose methotrexate.
Topics: Aged; Dermatitis, Phototoxic; Humans; Male; Methotrexate; Psoriasis; PUVA Therapy; Recurrence; Sunburn | 1994 |
Methotrexate in childhood psoriasis.
Topics: Administration, Oral; Adolescent; Arthritis, Psoriatic; Biopsy; Child; Child, Preschool; Dermatitis, Exfoliative; Disease-Free Survival; Female; Follow-Up Studies; Humans; Liver; Male; Methotrexate; Nausea; Psoriasis; Time Factors; Vomiting | 1994 |
Distribution of hepatic nerve fibers in liver diseases.
Topics: Autonomic Nervous System; Extracellular Matrix Proteins; Fibronectins; Hepatitis, Alcoholic; Humans; Hypertension, Portal; Laminin; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases; Methotrexate; Nerve Fibers; Portal Vein; Psoriasis | 1994 |
Methotrexate dose in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1994 |
Methotrexate revisited: effects of long-term treatment in psoriasis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1994 |
Prescribing in psoriasis.
Topics: Anthralin; Calcitriol; Coal Tar; Cyclosporins; Humans; Methotrexate; Phototherapy; Psoriasis; Retinoids | 1994 |
Human in vivo phosphorus 31 magnetic resonance spectroscopy of psoriasis. A noninvasive tool to monitor response to treatment and to study pathophysiology of the disease.
Topics: Adenosine Triphosphate; Administration, Cutaneous; Chromatography, High Pressure Liquid; Dermatitis, Exfoliative; Etretinate; Female; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Methotrexate; Phosphocreatine; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Phosphorus; Psoriasis; Skin; Steroids; Ultraviolet Therapy | 1994 |
The carcinogenic risk of treatments for severe psoriasis. Photochemotherapy Follow-up Study.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Methotrexate; Neoplasm Metastasis; Photochemotherapy; Psoriasis; PUVA Therapy; Risk Factors; Skin Neoplasms; Tars; Ultraviolet Rays | 1994 |
Fulminant hepatic failure after methotrexate and PUVA therapy for psoriasis.
Topics: Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; PUVA Therapy | 1993 |
Pulmonary cryptococcosis mimicking methotrexate pneumonitis.
Topics: Aged; Aged, 80 and over; Cryptococcosis; Cryptococcus neoformans; Diagnosis, Differential; Humans; Lung Diseases; Male; Methotrexate; Pneumonia; Psoriasis | 1993 |
Severe megaloblastic anemia in a patient receiving low-dose methotrexate for psoriasis.
Topics: Adult; Anemia, Megaloblastic; Female; Humans; Methotrexate; Psoriasis | 1993 |
Pancytopenia associated with low dose methotrexate therapy. A regional survey.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Urea Nitrogen; Canada; Creatinine; Dose-Response Relationship, Drug; Female; Folic Acid; Health Surveys; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis; Risk Factors; Surveys and Questionnaires; Trimethoprim, Sulfamethoxazole Drug Combination | 1993 |
Psoriasis: therapeutic aspects.
Topics: Adrenal Cortex Hormones; Anthralin; Cyclosporins; Drug Costs; Emollients; Humans; Keratolytic Agents; Methotrexate; Psoriasis; PUVA Therapy; Retinoids; Tars; Ultraviolet Therapy | 1993 |
Cutaneous malignancy related to cyclosporin A therapy.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Humans; Male; Methotrexate; Psoriasis; Skin Neoplasms | 1993 |
The annual cost of psoriasis.
Topics: Adult; Cyclosporine; Etretinate; Female; Health Care Costs; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Phototherapy; Psoriasis; PUVA Therapy; Retrospective Studies; Ultraviolet Therapy | 1993 |
An approach to the treatment of moderate to severe psoriasis with rotational therapy.
Topics: Combined Modality Therapy; Etretinate; Humans; Methotrexate; Psoriasis; PUVA Therapy; Tars; Ultraviolet Therapy | 1993 |
Treatment of gastrointestinal symptoms associated with methotrexate therapy for psoriasis.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Gastrointestinal Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1993 |
Ankylosing spondylitis successfully treated with methotrexate.
Topics: Adult; Humans; Male; Methotrexate; Psoriasis; Spondylitis, Ankylosing | 1993 |
[Suppression of bone marrow after drug interaction].
Topics: Adult; Bone Marrow; Drug Interactions; Female; Folic Acid; Humans; Methotrexate; Pancytopenia; Psoriasis; Trimethoprim, Sulfamethoxazole Drug Combination | 1993 |
Recurrent recall of sunburn by methotrexate.
Topics: Administration, Oral; Dermatologic Agents; Facial Dermatoses; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Recurrence; Sunburn; Sunlight | 1995 |
Sequential liver biopsies during long-term methotrexate treatment for psoriasis: a reappraisal.
Topics: Biopsy; Cost-Benefit Analysis; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Morbidity; Prospective Studies; Psoriasis | 1995 |
Methotrexate-linked ventricular arrhythmias.
Topics: Administration, Oral; Adult; Angina Pectoris; Arrhythmias, Cardiac; Biopsy; Coronary Angiography; Dermatologic Agents; Electrocardiography, Ambulatory; Endocardium; Heart Arrest; Humans; Male; Methotrexate; Myocardial Infarction; Psoriasis; Recurrence; Ventricular Premature Complexes | 1995 |
Interruption of long-term methotrexate treatment in psoriasis. Evaluation of clinical course and laboratory parameters after discontinuation and reintroduction of weekly oral methotrexate.
Topics: Administration, Oral; Administration, Topical; Aged; Alanine Transaminase; Aspartate Aminotransferases; Dermatologic Agents; Drug Administration Schedule; Drug Tolerance; Erythrocyte Indices; Evaluation Studies as Topic; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Methotrexate; Middle Aged; Motivation; Platelet Count; Psoriasis; Recurrence; Time Factors | 1995 |
Methotrexate osteopathy in long-term, low-dose methotrexate treatment for psoriasis and rheumatoid arthritis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Female; Fractures, Stress; Humans; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteoporosis; Psoriasis; Radiography | 1996 |
Pulmonary function in patients receiving long-term low-dose methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Lung; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Respiratory Function Tests; Rheumatic Diseases; Risk Factors | 1996 |
Proceedings of the Psoriasis Combination and Rotation Therapy Conference. Deer Valley, Utah, Oct. 7-9, 1994.
Topics: Administration, Cutaneous; Anti-Bacterial Agents; Cyclosporine; Dermatologic Agents; Drug Administration Schedule; Drug Combinations; Humans; Immunosuppressive Agents; Methotrexate; Photochemotherapy; Psoriasis; PUVA Therapy; Retinoids | 1996 |
Methotrexate and liver toxicity: role of surveillance liver biopsy. Conflict between guidelines for rheumatologists and dermatologists.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Biopsy; Dermatologic Agents; Humans; Liver; Methotrexate; Practice Guidelines as Topic; Psoriasis | 1996 |
Pustular psoriasis induced by hydroxychloroquine: a case report and review of the literature.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Hydroxychloroquine; Methotrexate; Psoriasis | 1996 |
The value of dynamic hepatic scintigraphy and serum aminoterminal propeptide of type III procollagen for early detection of methotrexate-induced hepatic damage in psoriasis patients.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Immunosuppressive Agents; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Prospective Studies; Psoriasis; Radionuclide Imaging | 1996 |
Association between pyoderma gangrenosum and psoriasis.
Topics: Adult; Humans; Male; Methotrexate; Psoriasis; Pyoderma Gangrenosum; Silver Sulfadiazine; Triamcinolone | 1996 |
[Therapeutic management of psoriasis].
Topics: Adrenal Cortex Hormones; Calcitriol; Cyclosporine; Dermatologic Agents; Humans; Immunosuppressive Agents; Keratolytic Agents; Methotrexate; Psoriasis; PUVA Therapy; Retinoids | 1996 |
Psoriasis.
Topics: Adrenal Cortex Hormones; Dermatologic Agents; Diagnosis, Differential; Humans; Methotrexate; Psoriasis | 1996 |
Accelerated nodulosis in a patient with psoriasis and arthritis during treatment with methotrexate.
Topics: Administration, Oral; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Female; Humans; Injections, Intramuscular; Methotrexate; Psoriasis; Rheumatic Nodule | 1995 |
Utilization of outpatient care for psoriasis.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Age Factors; Aged; Ambulatory Care; Anti-Inflammatory Agents; Child; Dermatologic Agents; Drug Prescriptions; Drug Utilization; Female; Ficusin; Glucocorticoids; Health Resources; Humans; Male; Methotrexate; Middle Aged; Photosensitizing Agents; Psoriasis; Retinoids; United States | 1996 |
Methotrexate-induced liver cirrhosis. Clinical, histological and serological studies--a further 10-year follow-up.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Dermatologic Agents; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1996 |
A 61-year-old man with psoriasis.
Topics: Cost of Illness; Decision Making; Dermatologic Agents; Family Practice; Health Care Costs; Humans; Male; Methotrexate; Middle Aged; Phototherapy; Physician's Role; Psoriasis; PUVA Therapy; Risk | 1996 |
Accelerated nodulosis in a patient with psoriasis and arthritis during treatment with methotrexate.
Topics: Aged; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans; Methotrexate; Psoriasis; Rheumatic Nodule | 1996 |
Skin tumors in photochemotherapy for psoriasis: a single-center follow-up of 496 patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Arsenic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child; Cocarcinogenesis; Dermatologic Agents; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Radiation Dosage; Regression Analysis; Retinoids; Retrospective Studies; Risk Factors; Skin Neoplasms; Tars; Ultraviolet Rays; X-Rays | 1996 |
Cyclosporin A down-regulates the LTA4 hydrolase level in human keratinocyte cultures.
Topics: 8,11,14-Eicosatrienoic Acid; Anti-Inflammatory Agents; Antineoplastic Agents; Calcitriol; Cells, Cultured; Cyclosporine; Dexamethasone; Down-Regulation; Epoxide Hydrolases; Humans; Interferon-gamma; Keratinocytes; Leukotriene B4; Methotrexate; Psoriasis; Thiophenes; Tretinoin | 1996 |
Plasma endothelin in psoriasis: possible relations to therapy and toxicity.
Topics: Acitretin; Cyclosporine; Endothelins; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Psoriasis; Ranitidine | 1996 |
Role of increased production of monocytes TNF-alpha, IL-1beta and IL-6 in psoriasis: relation to focal infection, disease activity and responses to treatments.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytokines; Dermatologic Agents; Female; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1; Interleukin-6; Kinetics; Male; Methotrexate; Middle Aged; Monocytes; Palatine Tonsil; Psoriasis; Tonsillectomy; Tumor Necrosis Factor-alpha | 1997 |
Methotrexate-induced toxic epidermal necrolysis in a patient with psoriasis.
Topics: Aged; Granulocyte Colony-Stimulating Factor; Humans; Male; Methotrexate; Psoriasis; Stevens-Johnson Syndrome | 1997 |
Therapy for psoriatic arthritis: sometimes a conflict for psoriasis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Humans; Methotrexate; Psoriasis | 1997 |
The profile and outcome of pustular psoriasis in Singapore: a report of 28 cases.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatologic Agents; Etretinate; Female; Humans; Keratolytic Agents; Male; Methotrexate; Middle Aged; Pregnancy; Psoriasis; PUVA Therapy; Singapore; Treatment Outcome | 1997 |
Methotrexate hepatotoxicity in psoriatics: report of 104 patients from Nova Scotia, with analysis of risks from obesity, diabetes and alcohol consumption during long term follow-up.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Biopsy; Child; Diabetes Complications; Disease Progression; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Incidence; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Nova Scotia; Obesity; Psoriasis; Retrospective Studies; Risk Factors; Time Factors | 1996 |
Epstein-Barr virus-associated lymphoproliferative disease during methotrexate therapy for psoriasis.
Topics: Antigens, Viral; B-Lymphocytes; Blotting, Southern; Capsid; Dermatologic Agents; DNA, Viral; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Genome, Viral; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; In Situ Hybridization; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Oncogene Proteins, Viral; Polymerase Chain Reaction; Psoriasis; Viral Matrix Proteins | 1997 |
Allergic contact dermatitis to propylene glycol in calcipotriene ointment.
Topics: Aged; Antioxidants; Calcitriol; Dermatitis, Allergic Contact; Dermatologic Agents; Female; Humans; Methotrexate; Ointments; Patch Tests; Propylene Glycol; Propylene Glycols; Psoriasis | 1997 |
[A patient with psoriatic arthritis due to generalized pustular psoriasis (von Zumbusch type)].
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Psoriatic; Betamethasone; Humans; Male; Methotrexate; Psoriasis | 1997 |
[Methotrexate and pregnancy].
Topics: Abortion, Spontaneous; Adult; Dermatologic Agents; Female; Humans; Methotrexate; Pregnancy; Psoriasis | 1997 |
Intermittent, short term use of methotrexate for exacerbations of psoriasis.
Topics: Acute Disease; Dermatologic Agents; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1997 |
Methotrexate induced pericarditis and pericardial effusion in psoriatic patient.
Topics: Adrenal Cortex Hormones; Dermatologic Agents; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Pericardial Effusion; Pericarditis; Psoriasis; Suction | 1998 |
[Question of the month. Is there any risk of prescribing methotrexate in psoriasis, the use of which is not legally allowed in France?].
Topics: Dermatologic Agents; France; Humans; Legislation, Drug; Methotrexate; Psoriasis | 1996 |
Methotrexate induces apoptotic cell death in human keratinocytes.
Topics: Apoptosis; Cell Count; Cell Nucleus; Cells, Cultured; Dermatologic Agents; DNA Fragmentation; Humans; Keratinocytes; Methotrexate; Psoriasis; Skin; Tumor Suppressor Protein p53 | 1998 |
[Inflammatory spondylodiscitis as a unique radiological manifestation of the SAPHO syndrome].
Topics: Acne Vulgaris; Anti-Inflammatory Agents; Discitis; Female; Humans; Hyperostosis; Immunosuppressive Agents; Lumbar Vertebrae; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteitis; Psoriasis; Radiography; Steroids; Syndrome; Synovitis | 1998 |
Screening of cobalamin metabolism in methotrexate-treated psoriatics.
Topics: Adult; Dermatologic Agents; Humans; Methotrexate; Methylmalonic Acid; Middle Aged; Psoriasis; Vitamin B 12 | 1998 |
Yellow nail pigmentation due to methotrexate.
Topics: Adult; Dermatologic Agents; Female; Humans; Methotrexate; Nail Diseases; Pigmentation Disorders; Psoriasis | 1998 |
Cost-effectiveness and cost-benefit analysis of using methotrexate vs Goeckerman therapy for psoriasis. A pilot study.
Topics: Cost-Benefit Analysis; Dermatologic Agents; Humans; Methotrexate; Pilot Projects; Psoriasis; Sensitivity and Specificity; Ultraviolet Therapy | 1998 |
Reduced folate carrier (RFC-1) gene expression in normal and psoriatic skin.
Topics: Adult; Aged; Carrier Proteins; Cell Line; Female; Folic Acid; Humans; Male; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Middle Aged; Psoriasis; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin | 1998 |
Low dose cyclosporin A and methotrexate in the treatment of psoriasis.
Topics: Adult; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis; Treatment Outcome | 1999 |
Treatments of generalized pustular psoriasis: a multicenter study in Japan.
Topics: Adult; Cyclosporine; Data Collection; Etretinate; Female; Glucocorticoids; Humans; Japan; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Tonsillectomy | 1999 |
Cost-effectiveness of methotrexate and Goeckerman therapy: a flawed analysis.
Topics: Cost-Benefit Analysis; Dermatologic Agents; Humans; Methotrexate; Psoriasis; Ultraviolet Therapy | 1999 |
Urinary adenosine and aminoimidazolecarboxamide excretion in methotrexate-treated patients with psoriasis.
Topics: Adenosine; Adult; Aged; Aminoimidazole Carboxamide; Female; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Male; Methotrexate; Middle Aged; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Psoriasis; Ribonucleotides | 1999 |
Pulmonary function changes in patients with psoriasis on methotrexate therapy.
Topics: Adult; Dermatologic Agents; Dose-Response Relationship, Drug; Female; Humans; Lung; Male; Methotrexate; Psoriasis; Respiratory Function Tests; Surveys and Questionnaires | 1999 |
Combination treatment with methotrexate and cyclosporin for severe recalcitrant psoriasis.
Topics: Adult; Chronic Disease; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1999 |
Exfoliative dermatitis after long-term methotrexate treatment of severe psoriasis.
Topics: Adult; Arthritis, Psoriatic; Dermatitis, Exfoliative; Dermatologic Agents; Diagnosis, Differential; Humans; Leg; Male; Methotrexate; Psoriasis | 1999 |
Fatal bacterial endocarditis following aortic valve replacement in a patient being treated with methotrexate.
Topics: Adult; Aortic Valve; Aortic Valve Stenosis; Endocarditis, Bacterial; Fatal Outcome; Heart Valve Prosthesis Implantation; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis | 1999 |
Methotrexate in the treatment of psoriasis.
Topics: Contraindications; Dermatologic Agents; Humans; Methotrexate; Psoriasis | 1999 |
Sex-specific differences in the treatment of severe psoriasis.
Topics: Abnormalities, Drug-Induced; Administration, Topical; Anti-Inflammatory Agents; Dermatologic Agents; Drug Utilization; Etretinate; Female; Glucocorticoids; Humans; Isotretinoin; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Sex Factors | 2000 |
The use of folic acid supplementation in psoriasis patients receiving methotrexate: a survey in the United Kingdom.
Topics: Dermatologic Agents; Drug Interactions; Drug Therapy, Combination; Erythrocyte Indices; Folic Acid; Humans; Methotrexate; Nausea; Practice Patterns, Physicians'; Psoriasis | 2000 |
Psoriatic onycho-pachydermo periostitis: treatment with methotrexate.
Topics: Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Nail Diseases; Periostitis; Psoriasis | 2000 |
The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up.
Topics: Biomarkers; Biopsy; Dermatologic Agents; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Retrospective Studies | 2001 |
Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate.
Topics: Adult; Antibodies, Monoclonal; Chronic Disease; Dermatologic Agents; Drug Therapy, Combination; Humans; Infliximab; Male; Methotrexate; Psoriasis; Recurrence; Tumor Necrosis Factor-alpha | 2001 |
Methotrexate in psoriasis: 26 years' experience with low-dose long-term treatment.
Topics: Drug Administration Schedule; Drug Interactions; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors | 2000 |
Widespread cutaneous carcinomas associated with human papillomaviruses 5, 14 and 20 after introduction of methotrexate in two long-term PUVA-treated patients.
Topics: Aged; Antirheumatic Agents; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Humans; Immunosuppressive Agents; Keratosis; Male; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Papillomaviridae; Psoriasis; PUVA Therapy; Skin; Skin Neoplasms | 2001 |
Liver biopsies and methotrexate: a time for reconsideration?
Topics: Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Methotrexate; Practice Guidelines as Topic; Psoriasis | 2001 |
Psoriatic onycho-pachydermo-periostitis.
Topics: Biopsy; Face; Humans; Male; Methotrexate; Middle Aged; Osteoarthropathy, Primary Hypertrophic; Penis; Psoriasis; Scalp; Sulfasalazine; Toes | 2001 |
Clearance in psoriasis treatment.
Topics: Dermatologic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Humans; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome | 2001 |
Treatment of psoriasis in the Nordic countries: a questionnaire survey from 5739 members of the psoriasis associations data from the Nordic Quality of Life Study.
Topics: Administration, Topical; Analysis of Variance; Anthralin; Anti-Inflammatory Agents; Calcitriol; Complementary Therapies; Cyclosporine; Dermatologic Agents; Europe; Female; Health Care Surveys; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Steroids; Surveys and Questionnaires | 2001 |
Pneumonitis complicating methotrexate therapy for pustular psoriasis.
Topics: Female; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Methotrexate; Middle Aged; Psoriasis | 2001 |
Ultrastructural and biosynthetic characteristics of epidermal cells in patients with psoriasis treated with antiproliferative drugs.
Topics: Biopsy; Cell Division; DNA; Epidermis; Etretinate; Growth Inhibitors; Humans; Intermediate Filaments; Methotrexate; Photochemotherapy; Psoriasis; RNA | 2001 |
Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate.
Topics: Acrodermatitis; Acute Disease; Aged; Antimetabolites; Drug Synergism; Drug Therapy, Combination; Humans; Kidney Failure, Chronic; Male; Methicillin Resistance; Methotrexate; Pancytopenia; Pneumonia, Staphylococcal; Propylthiouracil; Psoriasis; Staphylococcus aureus | 2001 |
Toxicity of methotrexate treatment in psoriasis and psoriatic arthritis--short- and long-term toxicity in 104 patients.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Central Nervous System Diseases; Child; Drug Interactions; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors; Transaminases | 2001 |
Delayed reactivation of haloperidol induced photosensitive dermatitis by methotrexate.
Topics: Adult; Antipsychotic Agents; Dermatitis, Photoallergic; Drug Synergism; Haloperidol; Hand Dermatoses; Humans; Immunosuppressive Agents; Male; Methotrexate; Psoriasis | 2002 |
Cost-effectiveness comparison of therapy for psoriasis with a methotrexate-based regimen versus a rotation regimen of modified cyclosporine and methotrexate.
Topics: Cost-Benefit Analysis; Cyclosporine; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; Humans; Male; Methotrexate; Models, Economic; Psoriasis; Severity of Illness Index; Treatment Outcome; United States | 2002 |
Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury.
Topics: Adult; Biopsy; Dermatologic Agents; Female; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors | 2001 |
Multiple anomalies in a fetus exposed to low-dose methotrexate in the first trimester.
Topics: Abnormalities, Multiple; Adolescent; Bone and Bones; Craniofacial Abnormalities; Depression; Digestive System; Digestive System Abnormalities; Female; Fetal Death; Heart Defects, Congenital; Humans; Infant, Newborn; Methotrexate; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Psoriasis; Sertraline; Ultrasonography, Prenatal | 2002 |
[Skeletal changes during the course of pustulosis palmoplantaris--report of two cases].
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Humans; Joint Diseases; Methotrexate; Middle Aged; Osteitis; Psoriasis; Radionuclide Imaging; Sacroiliac Joint; Sternoclavicular Joint | 2002 |
Letter: Intra-articular methotrexate.
Topics: Arthritis, Rheumatoid; Humans; Injections, Intra-Articular; Knee Joint; Male; Methotrexate; Middle Aged; Psoriasis | 1975 |
Liver biopsy in methotrexate-treated psoriatics-a re-evalution.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Child; Ethanol; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1975 |
[Eosinophilic leucocytes in the skin lesions of psoriasis and atopic dermatitis (author's transl)].
Topics: Age Factors; Dermatitis, Exfoliative; Eosinophils; Humans; Leukocyte Count; Methotrexate; Neurodermatitis; Psoriasis; Staining and Labeling | 1975 |
Generalized pustular psoriasis. A report on thirteen patients.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Female; Follow-Up Studies; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Streptococcal Infections | 1976 |
The relation of HL-A antigens to liver histology in methotrexate-treated psoriatics.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Histocompatibility Antigens; HLA Antigens; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
[Practical aspects of the cytostatic therapy of psoriasis].
Topics: Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis; Time Factors | 1976 |
Methotrexate therapy for psoriasis in elderly patients with impaired renal function.
Topics: Age Factors; Aged; Humans; Kidney Diseases; Methotrexate; Psoriasis | 1977 |
[Adverse effects of drugs on the skin--significance, survey and prospects].
Topics: Adrenergic beta-Antagonists; Allergens; Alopecia; Bleomycin; Drug Eruptions; Humans; Melanoma; Methotrexate; Penicillamine; Penicillins; Psoriasis; Skin Diseases, Vesiculobullous | 1978 |
Neutrophil chemotaxis in psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Child; Cyclic AMP; Cyclic GMP; Epidermis; Ethylenediamines; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neutrophils; Phosphodiesterase Inhibitors; Psoriasis; Skin; Theophylline | 1979 |
Pulmonary disease complicating intermittent methotrexate therapy of psoriasis.
Topics: Adult; Granuloma; Humans; Lung; Lung Diseases; Male; Methotrexate; Psoriasis; Radiography | 1979 |
[Inclusion of clinical-dermatological therapy into general practice? (author's transl)].
Topics: Family Practice; Humans; Keratosis; Methotrexate; Methoxsalen; Patient Care Team; Photochemotherapy; Psoriasis; Skin Diseases; Tretinoin | 1979 |
Psoriatic therapeutics and glucose-6-phosphate dehydrogenase.
Topics: Animals; Betamethasone; Cattle; Cyclic GMP; Drug Evaluation, Preclinical; Folic Acid; Glucosephosphate Dehydrogenase; Guinea Pigs; Kinetics; Methotrexate; Psoriasis | 1975 |
[Newer aspects of psoriasis therapy].
Topics: Cortisone; Cyclic AMP; Dehydroepiandrosterone; Heliotherapy; Humans; Immunity; Methotrexate; Ointments; Photochemotherapy; Psoriasis; Ultraviolet Therapy; Vitamin A | 1977 |
Psoriasis.
Topics: Adolescent; Adult; Aged; Coal Tar; Humans; Infant; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis | 1978 |
Aseptic (avascular) necrosis of the femoral head in psoriasis.
Topics: Adult; Female; Femur Head Necrosis; Humans; Male; Methotrexate; Middle Aged; Prednisone; Psoriasis; Radiography | 1979 |
Methotrexate-induced diffuse interstitial pulmonary fibrosis.
Topics: Aged; Brain Neoplasms; Carcinoma, Squamous Cell; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis; Pulmonary Fibrosis | 1979 |
Bowen's disease and squamous cell carcinoma. Occurrence in a patient with psoriasis after topical, systemic, and PUVA therapy.
Topics: Adult; Carcinoma, Squamous Cell; Coal Tar; Cocarcinogenesis; Glucocorticoids; Humans; Hydroxyurea; Male; Methotrexate; Methoxsalen; Penile Neoplasms; Photochemotherapy; Psoriasis; Skin Neoplasms; Vitamin A | 1979 |
Introduction of antifolics in psoriasis. A twenty-five year retrospect of antineoplastic agents in nonmalignant disease.
Topics: Adult; Aminopterin; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Male; Mechlorethamine; Methotrexate; Psoriasis; Retrospective Studies; Rheumatic Heart Disease | 1979 |
Methotrexate for psoriasis-revisited.
Topics: Adult; Arthritis; Female; Humans; Methotrexate; Psoriasis | 1979 |
Infantile pustular psoriasis.
Topics: Age Factors; Humans; Infant; Male; Methotrexate; Psoriasis; Suppuration | 1979 |
Psoriasis: topical and systemic therapy.
Topics: Administration, Topical; Adrenal Cortex Hormones; Anthralin; Coal Tar; Humans; Hydroxyurea; Keratolytic Agents; Methotrexate; Photochemotherapy; Psoriasis | 1979 |
[Various therapeutic problems in arthritic psoriasis].
Topics: Arthritis, Infectious; Balneology; Humans; Indomethacin; Methotrexate; Photochemotherapy; Psoriasis | 1979 |
Influence of cytotoxic agents on the development of lymphoid neoplasms in connective tissue diseases.
Topics: Humans; Leukemia, Lymphoid; Lymphoma; Methotrexate; Mixed Connective Tissue Disease; Psoriasis; Spondylitis, Ankylosing | 1979 |
[Uncritical self medication with methotrexate. A case of psoriasis for consideration].
Topics: Administration, Topical; Aged; Female; Humans; Methotrexate; Psoriasis; Self Administration | 1979 |
[Accumulation of radiophosphorus in psoriasis and its local therapy].
Topics: Administration, Topical; Adrenal Cortex Hormones; Cell Cycle; Humans; Methotrexate; Middle Aged; Phosphorus; Psoriasis | 1979 |
[The nosology of continuing suppurative acrodermatitis Hallopeau and of psoriasis pustulosa].
Topics: Acrodermatitis; Adrenal Cortex Hormones; Aged; Female; Heart Failure; Humans; Methotrexate; Pneumonia; Psoriasis | 1979 |
Methotrexate-induced pulmonary fibrosis.
Topics: Humans; Male; Methotrexate; Middle Aged; Psoriasis; Pulmonary Fibrosis | 1979 |
Cytogenetic effects of methotrexate on human cells in vivo: comparison between results obtained by chromosome studies on bone-marrow cells and blood lymphocytes and by the micronucleus test.
Topics: Bone Marrow; Cell Nucleus; Chromosome Aberrations; Chromosomes; Humans; Lymphocytes; Methotrexate; Mutagens; Myositis; Psoriasis | 1979 |
Methotrexate and fertility in men.
Topics: Adult; Fertility; Humans; Male; Methotrexate; Middle Aged; Phosphates; Psoriasis; Spermatogenesis; Testis | 1979 |
Radioimmunoassayable methotrexate concentrations in plasma and skin exudate of patients with psoriasis.
Topics: Adult; Aged; Humans; Methotrexate; Middle Aged; Psoriasis; Radioimmunoassay; Skin | 1979 |
Desmosomal abnormalities in the liver of methotrexate-treated psoriatics.
Topics: Cytoskeleton; Desmosomes; Humans; Liver; Methotrexate; Microscopy, Electron; Mitochondria, Liver; Psoriasis | 1977 |
When to try antineoplastic agents in psoriasis.
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Kidney Function Tests; Liver Function Tests; Methotrexate; Mycophenolic Acid; Psoriasis | 1977 |
[Cytostatic therapy of psoriasis].
Topics: Antineoplastic Agents; Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1979 |
[Photochemotherapy for psoriatic patients treated with corticosteroids and methotrexate].
Topics: Adrenal Cortex Hormones; Evaluation Studies as Topic; Humans; Methotrexate; Photochemotherapy; Psoriasis; Ultraviolet Therapy | 1977 |
Liver ultrastructure in psoriatics related to methotrexate therapy. 1. A prospective study of findings in hepatocytes from 24 patients before and after methotrexate treatment.
Topics: Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasm; Endoplasmic Reticulum; Golgi Apparatus; Humans; Liver; Lysosomes; Methotrexate; Mitochondria, Liver; Prospective Studies; Psoriasis | 1977 |
Liver ultrastructure in psoriatics related to methotrexate therapy. 2. Findings in bile ducts from 11 methotrexate treated psoriatics and 2 controls.
Topics: Adult; Aged; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; Female; Golgi Apparatus; Humans; Liver; Male; Methotrexate; Microvilli; Middle Aged; Mitochondria; Psoriasis | 1977 |
Effects of antipsoriasis drugs and metabolic inhibitors on the growth of epidermal cells in culture.
Topics: Animals; Anthralin; Antimetabolites; Azauridine; Cell Division; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; Guinea Pigs; Hydroxyurea; Methotrexate; Mycophenolic Acid; Psoriasis; Puromycin; Skin | 1978 |
Treatment of arthritis associated with psoriasis.
Topics: Analgesics; Arthritis; Humans; Methotrexate; Psoriasis | 1978 |
Methotrexate toxicity in the treatment of generalized pustular psoriasis.
Topics: Acute Disease; Aged; Agranulocytosis; Cell Division; DNA; Female; Granulocytes; Humans; Methotrexate; Mitosis; Psoriasis | 1978 |
Biological and biochemical actions of methotrexate in psoriasis.
Topics: Administration, Topical; Animals; Cell Survival; DNA; Dose-Response Relationship, Drug; Humans; Injections, Intradermal; Methotrexate; Mitosis; Psoriasis; Rats; Skin; Thymidine | 1978 |
[Experience with the photochemotherapy of psoriasis in Lausanne (author's transl)].
Topics: Administration, Oral; Cortisone; France; Humans; Methotrexate; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
Dermatology: psoriasis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anthralin; Child; Child, Preschool; Coal Tar; Epidermis; Ficusin; Humans; Methotrexate; Mitosis; Psoriasis; Ultraviolet Therapy | 1978 |
Fine structural changes in the liver of methotrexate-treated psoriatics.
Topics: Adult; Aged; Alcohol Drinking; Cell Membrane; Cell Nucleus; Chemical and Drug Induced Liver Injury; Desmosomes; Endoplasmic Reticulum; Female; Golgi Apparatus; Humans; Hyperplasia; Liver; Male; Methotrexate; Middle Aged; Mitochondria, Liver; Psoriasis; Time Factors | 1978 |
[Effectiveness of cytostatic agents on the psoriatic epidermal cell (author's transl)].
Topics: Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Methotrexate; Psoriasis | 1978 |
[A case of methotrexate-induced pneumonitis (author's transl)].
Topics: Adult; Female; Humans; Lupus Erythematosus, Systemic; Methotrexate; Psoriasis; Pulmonary Fibrosis | 1978 |
Generalized pustular psoriasis precipitated by lithium carbonate.
Topics: Adult; Bipolar Disorder; Female; Humans; Lithium; Methotrexate; Methoxsalen; Photochemotherapy; Psoriasis | 1978 |
Progressive interstitial lung disease from prolonged methotrexate therapy.
Topics: Aged; Humans; Lung Diseases; Male; Methotrexate; Psoriasis; Pulmonary Fibrosis; Radiography | 1978 |
Psoriasis: clinical aspects and management.
Topics: Administration, Topical; Age Factors; Azauridine; Fluorouracil; Humans; Hydroxyurea; Mechlorethamine; Methotrexate; Methoxsalen; Nitrosourea Compounds; Psoriasis; Thiotepa; Triamcinolone Acetonide | 1976 |
Current therapy of psoriasis.
Topics: Administration, Topical; Adrenal Cortex Hormones; Humans; Methotrexate; Psoriasis; Salicylates; Tars | 1977 |
Psoriatic arthritis.
Topics: Adolescent; Adult; Arthritis; Aspirin; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Radiography; Spondylitis | 1977 |
Studies of human semen in topical corticosteroid-treated and in methotrexate-treated psoriatics.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Glucocorticoids; Humans; Male; Methotrexate; Psoriasis; Sperm Motility; Spermatozoa | 1977 |
In vitro screening of biochemical activity of folic acid antagonists in skin.
Topics: Animals; Animals, Newborn; Chlorobenzenes; Depression, Chemical; DNA; Folic Acid Antagonists; Methotrexate; Psoriasis; Pyrimethamine; Pyrimidines; Quinazolines; Rats; Skin; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim | 1977 |
Controlling psoriasis.
Topics: Adrenal Cortex Hormones; Anthralin; Arthritis; Coal Tar; Diagnosis, Differential; Humans; Methotrexate; Parapsoriasis; Psoriasis | 1977 |
The true heartbreaks of psoriasis.
Topics: Humans; Hydroxyurea; Methotrexate; Psoriasis; Ultraviolet Therapy | 1977 |
[VI. Psoriasis arthropathica].
Topics: Anabolic Agents; Female; Humans; Joint Diseases; Methotrexate; Pregnancy; Psoriasis; Triamcinolone | 1977 |
Retinoic acid-induced psoriasiform lesions in guinea pigs: antagonism by anti-psoriasis agents.
Topics: Animals; Guinea Pigs; Hydrocortisone; Methotrexate; Psoriasis; Skin; Tretinoin; Triamcinolone Acetonide; Vitamin A | 1977 |
A cardiologist considers psoriasis.
Topics: Ascorbic Acid; Drug Combinations; Female; Ficusin; Folic Acid; Humans; Male; Methotrexate; Psoriasis; Ultraviolet Therapy | 1977 |
[Methotrexate in treatment of psoriasis].
Topics: Adult; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1977 |
Liver biopsies from psoriatics related to methotrexate therapy. 3. Findings in post-methotrexate liver biopsies from 160 psoriatics.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1977 |
Morphogenesis of fibrosis and cirrhosis in methotrexate-treated patients with psoriasis.
Topics: Adult; Aged; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis | 1977 |
[Acute necrotizing colitis in a psoriatic treated by methotrexát (author's transl)].
Topics: Adult; Colitis, Ulcerative; Female; Humans; Methotrexate; Necrosis; Psoriasis | 1977 |
Photochemotherapy in treatment of psoriatic variants.
Topics: Adrenal Cortex Hormones; Evaluation Studies as Topic; Female; Humans; Male; Methotrexate; Photochemotherapy; Psoriasis | 1977 |
[Psoriatic arthropathy].
Topics: Arthritis; Humans; Indomethacin; Methotrexate; Naproxen; Phenylbutazone; Psoriasis | 1977 |
Biopterin derivatives in human body fluids and tissues.
Topics: Adolescent; Adult; Biological Assay; Biopterins; Body Fluids; Brain Chemistry; Chemical Phenomena; Chemistry; Child; Chromatography, DEAE-Cellulose; Culture Media; Eukaryota; Female; Folic Acid; Humans; Leukemia; Liver; Male; Methotrexate; Middle Aged; Milk, Human; Psoriasis; Pteridines | 1976 |
Therapy of psoriasis 1975.
Topics: Administration, Topical; Adrenal Cortex Hormones; Azauridine; Depression, Chemical; Ficusin; Humans; Methotrexate; Methoxsalen; Mitosis; Mycophenolic Acid; Nucleic Acids; Psoriasis; Ultraviolet Therapy | 1976 |
Chemotherapy of psoriasis: ten years of experience.
Topics: Azauridine; Humans; Hydroxyurea; Methotrexate; Psoriasis; Retrospective Studies | 1976 |
Systemic chemotherapy for psoriasis: a national survey.
Topics: Adult; Azauridine; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Utilization; Female; Humans; Hydroxyurea; Liver; Methotrexate; Neoplasms; Psoriasis; Thrombophlebitis | 1976 |
Accidental kidney biopsies in psoriasis.
Topics: Adult; Aged; Biopsy; Female; Humans; Kidney; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
Letter: Renal function in methotrexate treated psoriatics.
Topics: Adult; Aged; Female; Humans; Kidney; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
Effect of methotrexate therapy in psoriatics on the Ito cells in liver biopsies, assessed by point-counting.
Topics: Adult; Aged; Biopsy, Needle; Cell Count; Cell Division; Female; Humans; Liver; Male; Methotrexate; Microscopy, Electron; Middle Aged; Psoriasis | 1976 |
Methotrexate-induced pneumonitis.
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Dose-Response Relationship, Drug; Eosinophilia; Female; Humans; Leukemia; Lung; Lymphoma; Male; Methotrexate; Middle Aged; Pneumonia; Psoriasis; Radiography; Retrospective Studies | 1976 |
[Treatment of psoriasis arthropathy with either azathioprine or methotrexate (author's transl)].
Topics: Adult; Arthritis; Azathioprine; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
Grand rounds. University of Kentucky College of Medicine. Psoriasis.
Topics: Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
[Immunosuppressive agents in the treatment of psoriasis].
Topics: Azauridine; Cyclophosphamide; Drug Evaluation; Humans; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Psoriasis | 1976 |
[Our therapeutic experiences with psoriasis in Morocco].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Drug Therapy, Combination; Female; Fluocinonide; Heliotherapy; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Morocco; Placebos; Podophyllin; Psoriasis; Psychophysiologic Disorders; Seasons; Sleep; Tars | 1976 |
Drug interaction in psoriasis.
Topics: Aged; Drug Interactions; Female; Humans; Male; Methotrexate; Middle Aged; Phenylbutazone; Psoriasis | 1976 |
[Treatment of psoriasis with methotrexate].
Topics: Humans; Methotrexate; Psoriasis | 1975 |
Treatment of psoriasis.
Topics: Adrenal Cortex Hormones; Anthralin; Coal Tar; Humans; Methotrexate; Methoxsalen; Psoriasis; Ultraviolet Therapy | 1976 |
Drugs for psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Methotrexate; Psoriasis | 1976 |
Psoriasis: trends in therapy.
Topics: Chlorpheniramine; Cortisone; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Organomercury Compounds; Psoriasis; Ultraviolet Therapy | 1976 |
Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective-prospective analysis.
Topics: Aged; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Liver; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Prostatic Neoplasms; Psoriasis; Retrospective Studies; Skin Neoplasms | 1975 |
Megaloblastic anemia in the management of severe psoriasis.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Hydroxyurea; Methotrexate; Middle Aged; Psoriasis | 1975 |
Treatment of psoriasis by methotrexate.
Topics: Adult; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1976 |
Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Azathioprine; B-Lymphocytes; Child; Chlorambucil; Collagen Diseases; Cyclophosphamide; Depression, Chemical; Drug Combinations; Female; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Methotrexate; Middle Aged; Prednisone; Psoriasis; T-Lymphocytes | 1975 |
Immunological responses of patients with psoriasis and the effect of treatment with methotrexate.
Topics: Adult; Female; Humans; Immune Adherence Reaction; Lectins; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Psoriasis; T-Lymphocytes | 1975 |
Letter: Complications during methotrexate therapy for psoriasis.
Topics: Adult; Bone Marrow; Hepatitis B; Hepatitis B Antigens; Humans; Male; Methotrexate; Pneumonia; Psoriasis | 1975 |
Effects of methotrexate esters on normal and psoriatic skin.
Topics: Chemical Phenomena; Chemistry; Chronic Disease; Deoxyuridine; Depression, Chemical; DNA; Humans; Lipids; Methotrexate; Psoriasis; Skin; Solubility; Thymidine | 1975 |
Letter: Liver disease in psoriatics.
Topics: Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis | 1975 |
Assay of therapeutic doses of methotrexate in body fluids of patients with psoriasis.
Topics: Administration, Oral; Aged; Biological Assay; Culture Media; Erythrocytes; Feces; Folic Acid; Humans; Infusions, Parenteral; Injections, Intramuscular; Kidney; Lactobacillus; Male; Methotrexate; Protein Binding; Psoriasis; Serum Albumin; Skin | 1975 |
[The treatment of psoriasis].
Topics: Adrenal Cortex Hormones; Anthralin; Humans; Liver; Methotrexate; Nitrogen Mustard Compounds; Ointments; Psoriasis; Salicylates; Ultraviolet Rays | 1975 |
Generalized pustular psoriasis on withdrawal of clobetasol propionate ointment.
Topics: Azathioprine; Betamethasone; Female; Humans; Male; Methotrexate; Middle Aged; Ointments; Psoriasis; Steroids, Chlorinated | 1975 |
[Vitamin A content of blood in patients with psoriasis during treatment with group B vitamins, pyrogenal and methotrexate].
Topics: Humans; Methotrexate; Psoriasis; Pyrogens; Vitamin A; Vitamin B Complex | 1975 |
[Development of malignancy during methotrexate treatment].
Topics: Bronchial Neoplasms; Carcinoma, Bronchogenic; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Psoriasis | 1975 |
Screening for 6- phosphogluconate dehydrogenase abnormalities in the blood of dermatological patients.
Topics: Humans; Methotrexate; Phosphogluconate Dehydrogenase; Psoriasis; Skin Diseases | 1975 |
Methotrexate and prednisolone treatment of a child with psoriatic arthritis.
Topics: Arthritis; Child; Drug Therapy, Combination; Female; Humans; Methotrexate; Prednisolone; Psoriasis | 1975 |
Azaribine therapy for psoriasis. Evaluation of potential effects on the liver and other organ systems.
Topics: Adolescent; Adult; Azauridine; Biopsy; Brain; Cardiovascular System; Chemical and Drug Induced Liver Injury; Digestive System; Female; Hematopoietic System; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1975 |
Mouse vaginal assay for topically effective chemotherapeutic agents.
Topics: Administration, Topical; Animals; DNA; Drug Evaluation, Preclinical; Female; In Vitro Techniques; Methotrexate; Mice; Mucous Membrane; Protein Biosynthesis; Psoriasis; RNA; Vagina | 1975 |
In vitro evaluation of methotrexate and azathioprine for antipsoriatic activity.
Topics: Acid Phosphatase; Azathioprine; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Leucyl Aminopeptidase; Methotrexate; Oxygen Consumption; Pentosephosphates; Psoriasis; Skin | 1975 |
Methotrexate pneumonitis in a psoriatic.
Topics: Adult; Drug Hypersensitivity; Dyspnea; Eosinophilia; Female; Humans; Methotrexate; Pneumonia; Psoriasis; Radiography | 1975 |
[Dynamics of some indices of interstitial metabolism in patients with psoriasis during treatment with methotrexate].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Fructose-Bisphosphate Aldolase; Humans; Liver; Male; Methotrexate; Middle Aged; Minerals; Proteins; Psoriasis; Transaminases | 1975 |
[Experience in the treatment of psoriasis].
Topics: Adolescent; Adult; Animals; Child; Evaluation Studies as Topic; Glucocorticoids; Humans; Immunotherapy; Measles Vaccine; Methotrexate; Middle Aged; Psoriasis; Pyrogens; Vitamins | 1975 |
[Tissue immunology in psoriasis. I. Changes in the immunologic mechanism caused by methotrexate].
Topics: Adult; Female; Humans; Immunity, Cellular; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Psoriasis | 1975 |
[Letter: Has Methotrexate a mutagenic effect?].
Topics: Adult; Female; Germ Cells; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Pregnancy; Psoriasis | 1976 |
[Measles- - antibodies in psoriatic patients with and without methotrexate therapy].
Topics: Antibodies, Viral; Humans; Immunosuppression Therapy; Measles; Methotrexate; Psoriasis | 1976 |
Letter: Psoriasis.
Topics: Dose-Response Relationship, Drug; Humans; Methotrexate; Psoriasis | 1976 |
Liver biopsies from psoriatics related to methotrexate therapy. 1. Findings in 123 consecutive non-methotrexate treated patients.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspartate Aminotransferases; Body Weight; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis | 1976 |
Liver biopsies from psoriatics related to methotrexate therapy. 2. Findings before and after methotexate therapy in 88 patients. A blind study.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aspartate Aminotransferases; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis | 1976 |
Methotrexate hepatotoxicity in psoriatic patients submitted to long-term therapy.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Child; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1992 |
Folinic acid rescue used routinely in psoriatic patients with known methotrexate "sensitivity".
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Psoriasis | 1992 |
Possible role of histamine in pathogenesis of autoimmune diseases: implications for immunotherapy with histamine-2 receptor antagonists.
Topics: Autoimmune Diseases; Autoimmunity; Cyclosporine; Histamine; Histamine H2 Antagonists; Humans; Immunity, Cellular; Immunotherapy; Major Histocompatibility Complex; Methotrexate; Models, Biological; Psoriasis; T-Lymphocytes | 1992 |
Dynamic hepatic scintigraphy in the screening of psoriatic patients for methotrexate-induced hepatotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Needle; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Psoriasis; Radionuclide Imaging; Sensitivity and Specificity | 1992 |
Anti-proliferative effects of protein kinase C inhibitors in human keratinocytes.
Topics: Cell Division; Cell Line; DNA; Enzyme Inhibitors; Humans; Keratinocytes; Methotrexate; Protein Biosynthesis; Protein Kinase C; Psoriasis | 1992 |
How to improve the risk-benefit ratio of cyclosporin therapy for psoriasis.
Topics: Cyclosporine; Drug Therapy, Combination; Humans; Kidney Diseases; Methotrexate; Psoriasis; PUVA Therapy; Retinoids | 1992 |
The efficacy of methotrexate in psoriasis--a review of 40 cases.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1992 |
Psoriasis symposium. Methotrexate.
Topics: Drug Interactions; Humans; Liver; Methotrexate; Psoriasis | 1992 |
Liver biopsy versus ultrasound in methotrexate-treated psoriasis: a decision analysis.
Topics: Algorithms; Biopsy; Decision Support Techniques; Humans; Liver; Liver Diseases; Methotrexate; Psoriasis; Ultrasonography | 1992 |
Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis.
Topics: Arthritis, Psoriatic; Biomarkers; Humans; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 1992 |
Visual field defects during low-dose methotrexate therapy.
Topics: Adult; Female; Humans; Methotrexate; Optic Atrophy; Papilledema; Psoriasis; Vision Disorders; Visual Fields | 1992 |
Subcutaneous administration of methotrexate.
Topics: Costs and Cost Analysis; Humans; Injections, Subcutaneous; Lymphoma, T-Cell, Cutaneous; Methotrexate; Psoriasis | 1992 |
Etretinate increases carcinoembryonic antigen in palmar scrapings.
Topics: Carcinoembryonic Antigen; Etretinate; Hand; Humans; Methotrexate; Psoriasis; Skin | 1992 |
[Hepatocellular carcinoma in a patient with psoriasis and methotrexate-induced cirrhosis].
Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis | 1991 |
Disseminated histoplasmosis in patients receiving low-dose methotrexate therapy for psoriasis.
Topics: Acute Disease; Adult; Amphotericin B; Female; Histoplasmosis; Humans; Immunity, Cellular; Male; Methotrexate; Opportunistic Infections; Psoriasis; Time Factors | 1992 |
[Methotrexate--indications and adverse effects].
Topics: Arthritis, Psoriatic; Dose-Response Relationship, Drug; Humans; Methotrexate; Psoriasis | 1991 |
[Methotrexate and psoriasis].
Topics: Contraindications; Methotrexate; Psoriasis | 1991 |
Methotrexate interactions.
Topics: Adult; Drug Interactions; Female; Humans; Methotrexate; Pancytopenia; Psoriasis; Trimethoprim, Sulfamethoxazole Drug Combination | 1991 |
Efficacy of bimolane in the Malassezia ovalis model of psoriasis.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Betamethasone Valerate; Disease Models, Animal; Female; Injections, Intravenous; Malassezia; Methotrexate; Psoriasis; Rabbits; Razoxane; Skin | 1991 |
What's new in dermatology? Outpatient treatment of severe psoriasis.
Topics: Ambulatory Care; Etretinate; Humans; Methotrexate; Phototherapy; Psoriasis | 1991 |
[Psoriasis--the great hidden widespread disease].
Topics: Administration, Topical; Anti-Inflammatory Agents; Combined Modality Therapy; Glucocorticoids; Humans; Methotrexate; Psoriasis; PUVA Therapy; Quality of Life | 1991 |
Serum aminoterminal propeptide of type III procollagen in psoriasis and psoriatic arthritis: relation to liver fibrosis and arthritis.
Topics: Alkaline Phosphatase; Arthritis, Psoriatic; Aspartate Aminotransferases; Clinical Enzyme Tests; Humans; Liver; Liver Cirrhosis; Methotrexate; Peptide Fragments; Procollagen; Psoriasis | 1991 |
Low-dose methotrexate therapy and hepatotoxicity. The view of the hepatologist.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis | 1991 |
Neutropenia due to low-dose methotrexate therapy for psoriasis and rheumatoid arthritis may be fatal.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Drug Interactions; Female; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Penicillins; Psoriasis; Retrospective Studies | 1991 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 51-1991. A 68-year-old man with recurrent fever and diarrhea after treatment for lymphoma.
Topics: Aged; Anemia, Megaloblastic; Bone Marrow; Folic Acid Deficiency; Hematopoietic Stem Cells; Humans; Male; Methotrexate; Psoriasis | 1991 |
Cyclosporin toxicity.
Topics: Adult; Aged; Chronic Disease; Cyclosporins; Drug Synergism; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1990 |
Cyclosporin versus methotrexate toxicity in psoriasis.
Topics: Cyclosporins; Humans; Liver; Methotrexate; Psoriasis | 1990 |
Psoriasis and polyneuropathy. Three case histories.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Psoriasis; Skin | 1990 |
Systemic drug therapy for psoriasis. The most critical issues.
Topics: Cyclosporins; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1991 |
Psoriasis therapy and the risk of skin cancers.
Topics: Adult; Female; Humans; Male; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; Risk Factors; Skin Neoplasms | 1991 |
Kidney biopsies in methotrexate-treated psoriatics.
Topics: Adult; Aged; Biopsy; Female; Fibrosis; Follow-Up Studies; Humans; Kidney; Male; Methotrexate; Middle Aged; Psoriasis | 1990 |
Cyclosporine and methotrexate: a dangerous combination.
Topics: Cyclosporins; Drug Therapy, Combination; Humans; Methotrexate; Psoriasis | 1990 |
Methotrexate induced pneumonitis in a young woman with psoriasis and rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Lung; Methotrexate; Psoriasis; Pulmonary Fibrosis | 1990 |
Extracorporeal photopheresis in psoriasis vulgaris: clinical and immunologic observations.
Topics: Adolescent; Adult; Chronic Disease; Drug Administration Schedule; Female; Humans; Immunoglobulin E; Immunophenotyping; Interleukin-2; Male; Methotrexate; Photochemotherapy; Psoriasis; Recurrence; Skin Tests | 1990 |
Interaction of etretinate with methotrexate pharmacokinetics in psoriatic patients.
Topics: Drug Interactions; Drug Therapy, Combination; Etretinate; Half-Life; Humans; Methotrexate; Psoriasis | 1990 |
Serum type III procollagen peptide, dynamic liver function tests and hepatic fibrosis in psoriatic patients receiving methotrexate.
Topics: Adult; Aged; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1990 |
Methotrexate: anti-inflammatory or antiproliferative?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Cell Survival; Humans; Methotrexate; Psoriasis | 1990 |
Methotrexate and liver biopsies. Is it really necessary?
Topics: Arthritis, Rheumatoid; Biopsy; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1990 |
Methotrexate-induced cirrhosis requiring liver transplantation in three patients with psoriasis. A word of caution in light of the expanding use of this 'steroid-sparing' agent.
Topics: Adult; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Liver Transplantation; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1990 |
Methotrexate treatment of psoriatic arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis; Blood Sedimentation; Female; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 1987 |
Methotrexate hepatotoxicity and concentrations of methotrexate and folate in erythrocytes--relation to liver fibrosis and cirrhosis.
Topics: Adult; Aged; Erythrocytes; Female; Folic Acid; Humans; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1987 |
Natural and Chang liver cell cytotoxic studies of methotrexate-treated psoriatic patients with liver cirrhosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Liver; Liver Cirrhosis; Lymphocyte Activation; Methotrexate; Middle Aged; Psoriasis | 1988 |
Malignant melanoma associated with multiple therapies for psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Coal Tar; Humans; Hydroxyurea; Male; Melanoma; Methotrexate; Photochemotherapy; Phototherapy; Psoriasis; Skin Neoplasms | 1989 |
Methotrexate dosage in patients aged over 50 with psoriasis.
Topics: Aged; Dose-Response Relationship, Drug; Humans; Methotrexate; Middle Aged; Psoriasis | 1989 |
[Extensive erosive hemorrhagic lesions in psoriasis plaques caused by methotrexate poisoning].
Topics: Aged; Dose-Response Relationship, Drug; Drug Eruptions; Female; Humans; Methotrexate; Psoriasis; Skin Ulcer | 1989 |
Methotrexate serum-level determinations during low-dose therapy of rheumatoid and psoriatic arthritis.
Topics: Arthritis, Rheumatoid; C-Reactive Protein; Electron Spin Resonance Spectroscopy; Female; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis | 1989 |
Serum aminoterminal propeptide of type III procollagen. A non-invasive test for liver fibrogenesis in methotrexate-treated psoriatics.
Topics: Biomarkers; Female; Follow-Up Studies; Humans; Liver Cirrhosis; Male; Methotrexate; Peptide Fragments; Procollagen; Psoriasis; Radioimmunoassay | 1989 |
Development of metastatic skin cancer during methotrexate therapy for psoriasis.
Topics: Aged; Carcinoma, Squamous Cell; Humans; Male; Methotrexate; Psoriasis | 1989 |
[Alpha 1-fetoprotein--a marker of potential PUVA side-effects in psoriasis?].
Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Arthritis; Humans; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; PUVA Therapy | 1985 |
Fasting plasma homocysteine as a sensitive parameter of antifolate effect: a study of psoriasis patients receiving low-dose methotrexate treatment.
Topics: Adult; Aged; Aged, 80 and over; Fasting; Female; Folic Acid Deficiency; Homocysteine; Humans; Male; Methionine; Methotrexate; Middle Aged; Psoriasis; Regression Analysis | 1989 |
Short-term methotrexate administration by low-dose infusion--does it influence clearance of psoriasis?
Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Female; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis | 1989 |
Central nervous system toxicity associated with weekly low-dose methotrexate treatment.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Brain; Creatinine; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1989 |
[Current treatment of psoriasis].
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cyclosporins; Glucocorticoids; Humans; Methotrexate; Psoriasis; PUVA Therapy; Retinoids | 1989 |
[Pancytopenia during low-dose oral methotrexate therapy of psoriatic arthritis].
Topics: Administration, Oral; Aged; Arthritis; Blood Transfusion; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocyte Transfusion; Female; Humans; Kidney Failure, Chronic; Methotrexate; Pancytopenia; Platelet Transfusion; Pseudomonas Infections; Psoriasis; Pulmonary Fibrosis | 1989 |
[Metastasizing squamous cell carcinoma in patients with psoriasis treated with immunosuppressive agents].
Topics: Aged; Carcinoma, Squamous Cell; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1989 |
Detection of hepatotoxicity associated with methotrexate therapy for psoriasis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Cholecystitis; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Psoriasis; Retrospective Studies; Risk Factors; ROC Curve; Time Factors | 1989 |
The role of liver biopsies in psoriatic patients receiving long-term methotrexate treatment. Improvement in liver abnormalities after cessation of treatment.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Biopsy; Drug Administration Schedule; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors; Time Factors | 1989 |
Validation of a diagnostic test. Epidemiologic principles in dermatology.
Topics: Biopsy; Humans; Liver; Liver Function Tests; Methotrexate; Predictive Value of Tests; Psoriasis; ROC Curve | 1989 |
Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriatic arthropathy.
Topics: Adolescent; Arthritis; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ibuprofen; Immunosuppression Therapy; Methotrexate; Pneumonia, Pneumocystis; Psoriasis | 1989 |
[Immunosuppressive treatment of patients with psoriasis].
Topics: Humans; Methotrexate; Psoriasis | 1989 |
Hepatic metabolic function in patients receiving long-term methotrexate therapy: comparison with topically treated psoriatics, patient controls and cirrhotics.
Topics: Aged; Alkaline Phosphatase; Antipyrine; Female; gamma-Glutamyltransferase; Humans; Indocyanine Green; Kinetics; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1985 |
Interaction between methotrexate and non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Apazone; Drug Interactions; Humans; Methotrexate; Psoriasis | 1986 |
Methotrexate and retinoids in combination for psoriasis.
Topics: Chronic Disease; Drug Synergism; Drug Therapy, Combination; Etretinate; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retinoids | 1987 |
[Problems of the clinico-biochemical polymorphism of psoriasis in Uzbekistan].
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Psoriasis; Sex Factors; Uzbekistan | 1985 |
Drug eruption caused by nitrazepam in a patient with severe pustular psoriasis successfully treated with methotrexate and etretinate.
Topics: Adult; Drug Eruptions; Etretinate; Humans; Male; Methotrexate; Nitrazepam; Psoriasis | 1987 |
Methotrexate inhibits the leukotriene B4 induced intraepidermal accumulation of polymorphonuclear leukocytes.
Topics: Adult; Chemotaxis, Leukocyte; Epidermis; Female; Humans; Leukocytes; Leukotriene B4; Male; Methotrexate; Middle Aged; Neutrophils; Psoriasis | 1985 |
An investigation of the ability of antipsoriatic drugs to inhibit calmodulin activity: a possible mode of action of dithranol (anthralin).
Topics: Animals; Anthracenes; Anthralin; Calmodulin; Cattle; Coal Tar; Etretinate; Hydrocortisone; In Vitro Techniques; Methotrexate; Methoxsalen; Oxidation-Reduction; Phosphoric Diester Hydrolases; Psoriasis | 1986 |
Reduction of leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes by methotrexate in psoriasis.
Topics: Adult; Humans; Leukotriene B4; Methotrexate; Middle Aged; Neutrophils; Psoriasis; Skin | 1987 |
Generalized pustular psoriasis after renal transplantation--failure to suppress with cyclosporin A.
Topics: Acute Disease; Adult; Cyclosporins; Humans; Kidney Transplantation; Male; Methotrexate; Psoriasis | 1988 |
Near fatal drug interactions with methotrexate given for psoriasis.
Topics: Aged; Aged, 80 and over; Drug Interactions; Female; Humans; Methotrexate; Naproxen; Necrosis; Pancytopenia; Psoriasis; Skin; Skin Ulcer; Trimethoprim | 1987 |
[Blood cell concentration of methotrexate in long-term therapy of inflammatory rheumatic diseases].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Erythrocytes; Female; Humans; Long-Term Care; Male; Methotrexate; Middle Aged; Psoriasis | 1988 |
[Lyell's syndrome from the repeat treatment of psoriasis with methotrexate].
Topics: Aged; Female; Humans; Methotrexate; Psoriasis; Recurrence; Remission Induction; Stevens-Johnson Syndrome | 1988 |
Aminoterminal propeptide of type III procollagen in methotrexate-induced liver fibrosis and cirrhosis.
Topics: Adult; Aged; Biomarkers; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis | 1988 |
Intestinal folate absorption in methotrexate treated psoriatic patients.
Topics: Adult; Aged; Female; Folic Acid; Humans; Intestinal Absorption; Male; Methotrexate; Middle Aged; Psoriasis | 1988 |
Methotrexate therapy for psoriasis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Female; Folic Acid Deficiency; Humans; Male; Methotrexate; Middle Aged; Pancytopenia; Psoriasis | 1988 |
Methotrexate-associated hepatotoxicity: retrospective analysis of 210 patients with rheumatoid arthritis.
Topics: Aged; Arthritis; Arthritis, Rheumatoid; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk Factors | 1988 |
The use of antipyrine clearance to measure liver damage in psoriatic patients receiving methotrexate.
Topics: Adult; Antipyrine; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Psoriasis; Saliva | 1988 |
Methotrexate-induced impairment of taste acuity.
Topics: Adult; Folic Acid; Humans; Male; Methotrexate; Nervous System Diseases; Psoriasis; Taste | 1988 |
Treatment of psoriasis with 6-thioguanine.
Topics: Biopsy; Drug Administration Schedule; Drug Resistance; Female; Follow-Up Studies; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Thioguanine | 1988 |
[How does methotrexate work in psoriasis?].
Topics: Cell Division; DNA Replication; Humans; Methotrexate; Psoriasis; Skin | 1988 |
Short-term, high-dose methotrexate therapy in a case of severe psoriatic arthritis.
Topics: Adult; Arthritis; Female; Humans; Methotrexate; Psoriasis | 1988 |
Pancytopenia following low-dose oral methotrexate therapy for psoriasis.
Topics: Administration, Oral; Aged; Female; Humans; Methotrexate; Middle Aged; Pancytopenia; Psoriasis | 1988 |
Pancytopenia following low-dose methotrexate therapy.
Topics: Humans; Methotrexate; Pancytopenia; Psoriasis; Risk Factors | 1988 |
Pharmacokinetics of methotrexate in continuous ambulatory peritoneal dialysis.
Topics: Adult; Female; Humans; Methotrexate; Peritoneal Dialysis, Continuous Ambulatory; Psoriasis | 1988 |
Methotrexate induced skin necrosis in psoriasis.
Topics: Aged; Female; Humans; Methotrexate; Necrosis; Psoriasis; Skin Diseases | 1987 |
Methotrexate toxicity in a patient receiving trimethoprim-sulfamethoxazole.
Topics: Aged; Anti-Infective Agents, Urinary; Arthritis; Drug Combinations; Humans; Male; Methotrexate; Psoriasis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1987 |
Flow cytometric quantification of T6-positive cells in psoriatic epidermis after PUVA and methotrexate therapy.
Topics: Epidermis; Flow Cytometry; Humans; Langerhans Cells; Methotrexate; Psoriasis; PUVA Therapy; T-Lymphocytes | 1987 |
Pancytopenia induced by the interaction between methotrexate and trimethoprim-sulfamethoxazole.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Drug Combinations; Drug Therapy, Combination; Female; Humans; Methotrexate; Pancytopenia; Psoriasis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1987 |
[What is established in the treatment of psoriasis?].
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Etretinate; Glucocorticoids; Humans; Mercury; Methotrexate; Psoriasis; PUVA Therapy; Tars; Ultraviolet Therapy | 1987 |
A comparison of liver ultrasound with liver biopsy histology in psoriatics receiving long-term methotrexate therapy.
Topics: Adult; Aged; Biopsy; Female; Fibrosis; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors; Ultrasonography | 1987 |
[The coexistence of systemic lupus erythematosus and psoriatic arthritis].
Topics: Adult; Arthritis; Female; Humans; Lupus Erythematosus, Systemic; Methotrexate; Psoriasis | 1986 |
Methotrexate and the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Arthritis; Homosexuality; Humans; Male; Methotrexate; Psoriasis | 1987 |
The aminopyrine breath test, an inadequate early indicator of methotrexate-induced liver disease in patients with psoriasis.
Topics: Aminopyrine; Breath Tests; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methotrexate; Psoriasis | 1987 |
Methotrexate inhibits the human C5a-induced skin response in patients with psoriasis.
Topics: Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Erythema; Female; Humans; Intradermal Tests; Male; Methotrexate; Middle Aged; Monocytes; Neutrophils; Psoriasis; Skin | 1987 |
Cryptococcosis associated with low-dose methotrexate for arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Cryptococcosis; Humans; Male; Methotrexate; Middle Aged; Opportunistic Infections; Psoriasis | 1987 |
The current status of methotrexate use in rheumatic diseases.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Child; Female; Humans; Methotrexate; Myositis; Pregnancy; Psoriasis | 1986 |
Psoriasis practices.
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Humans; Methotrexate; Psoriasis; PUVA Therapy | 1987 |
The treatment of severe psoriasis. A national survey.
Topics: Adult; Combined Modality Therapy; Dermatology; Drug Administration Schedule; Humans; Methotrexate; Middle Aged; Population Surveillance; Psoriasis; PUVA Therapy; Retinoids; Steroids; Surveys and Questionnaires; Ultraviolet Therapy; United States | 1987 |
Magnetic resonance imaging as a screening procedure for methotrexate induced liver damage.
Topics: Adolescent; Adult; Aged; Biopsy; Female; Humans; Liver; Liver Cirrhosis; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Psoriasis | 1987 |
[Methotrexate: from sword to ploughshare?].
Topics: Arthritis, Rheumatoid; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Psoriasis | 1987 |
[Methotrexate in the treatment of psoriasis].
Topics: Drug Administration Schedule; Drug Interactions; Humans; Methotrexate; Psoriasis; Time Factors | 1987 |
[Acute bone marrow suppression with low-dosage methotrexate].
Topics: Aged; Arthritis, Rheumatoid; Bone Marrow; Female; Half-Life; Humans; Leukopenia; Methotrexate; Pancytopenia; Psoriasis; Thrombocytopenia | 1987 |
Hepatotoxicity after long-term methotrexate therapy.
Topics: Administration, Oral; Arthritis, Rheumatoid; Ascites; Aspartate Aminotransferases; Biopsy, Needle; Humans; Liver Cirrhosis; Methotrexate; Psoriasis; Retrospective Studies; Serum Albumin; Time Factors | 1986 |
Electroencephalographic examination in seven patients treated with methotrexate for psoriasis.
Topics: Adult; Brain; Electroencephalography; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1986 |
Methotrexate pharmacokinetics in psoriatic patients developing hepatic fibrosis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Kinetics; Methotrexate; Psoriasis; Risk; Time Factors | 1986 |
Methotrexate toxicity precipitated by azapropazone.
Topics: Adult; Apazone; Bone Marrow Diseases; Drug Interactions; Female; Humans; Joint Diseases; Methotrexate; Psoriasis; Triazines | 1986 |
Low-dose weekly oral methotrexate therapy for inflammatory arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Mixed Connective Tissue Disease; Prospective Studies; Psoriasis | 1986 |
Methotrexate in erythrocytes of patients with psoriasis.
Topics: Administration, Oral; Adult; Aged; Drug Administration Schedule; Erythrocytes; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Psoriasis | 1986 |
Liver biopsies from psoriatics treated with methotrexate.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 1986 |
Combination methotrexate, PUVA and UVB therapy in the treatment of psoriasis.
Topics: Adult; Aged; Combined Modality Therapy; Drug Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1986 |
Nonmelanoma skin tumors in long-term photochemotherapy treatment of psoriasis. An 8-year follow-up study.
Topics: Adult; Aged; Aging; Arsenic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etretinate; Follow-Up Studies; Humans; Melanoma; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Skin Neoplasms | 1986 |
Long-term effects of etretinate on the liver in psoriasis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Etretinate; Female; Humans; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1987 |
Pulmonary function in patients on long-term, low-dose methotrexate.
Topics: Adult; Aged; Female; Humans; Lung; Male; Methotrexate; Middle Aged; Pneumonia; Psoriasis; Respiratory Function Tests; Time Factors | 1986 |
Pulmonary complications following methotrexate therapy.
Topics: Adult; Female; Humans; Lung Volume Measurements; Male; Methotrexate; Middle Aged; Pneumonia; Psoriasis; Pulmonary Fibrosis | 1987 |
Neutrophil and monocyte chemotaxis in methotrexate-treated psoriasis patients.
Topics: Adult; Aged; Chemotaxis, Leukocyte; Depression, Chemical; Female; Humans; Male; Methotrexate; Middle Aged; Monocytes; Neutrophils; Psoriasis; Time Factors | 1985 |
Generalized pustular psoriasis provoked by propranolol.
Topics: Aged; Humans; Male; Methotrexate; Propranolol; Psoriasis; Skin Diseases, Vesiculobullous; Tremor | 1985 |
Ultrasound as a screening procedure for methotrexate-induced hepatic damage in severe psoriasis.
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Ultrasonography | 1985 |
Treatment of psoriasis. Results achieved by the Johannesburg Hospital Psoriasis Clinic.
Topics: Adult; Aged; Anthralin; Coal Tar; Etretinate; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Ultraviolet Therapy | 1986 |
Megaloblastic anaemia and methotrexate treatment.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid Deficiency; Humans; Methotrexate; Middle Aged; Psoriasis | 1986 |
Combination therapy for psoriasis with methotrexate and etretinate.
Topics: Adult; Carcinoma, Basal Cell; Drug Therapy, Combination; Etretinate; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Neoplasms, Radiation-Induced; Psoriasis; PUVA Therapy; Skin Neoplasms | 1986 |
Oral methotrexate.
Topics: Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis | 1986 |
Low incidence of hepatotoxicity associated with long-term, low-dose oral methotrexate in treatment of refractory psoriasis, psoriatic arthritis, and rheumatoid arthritis. An acceptable risk/benefit ratio.
Topics: Adult; Aged; Alcohol Drinking; Arthritis; Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 1985 |
[Oral methotrexate therapy: pro and con].
Topics: Administration, Oral; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Humans; Methotrexate; Psoriasis; Risk | 1985 |
[Photochemotherapy combined with low-dose methotrexate in severe forms of psoriasis].
Topics: Adolescent; Adult; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Photochemotherapy; Psoriasis; Recurrence; Time Factors | 1985 |
Predictive value of HLA antigen for methotrexate-induced liver damage in patients with psoriasis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Histocompatibility Testing; HLA Antigens; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Risk | 1985 |
Impact of methotrexate therapy on the folate status of psoriatic patients.
Topics: Adult; Aged; Drug Administration Schedule; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1985 |
Management of the seronegative spondyloarthropathies.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis; Arthritis, Reactive; Fractures, Spontaneous; Hip Prosthesis; Humans; Methotrexate; Osteotomy; Physical Therapy Modalities; Psoriasis; Spondylitis; Spondylitis, Ankylosing | 1985 |
Megaloblastic anaemia in psoriatic patients treated with methotrexate.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1985 |
Methotrexate maintenance therapy and liver damage in psoriasis.
Topics: Adult; Age Factors; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis | 1985 |
Changes in liver histology during methotrexate therapy of psoriasis correlated to the concentration of methotrexate and folate in erythrocytes.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Folic Acid; Humans; Liver Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1985 |
The response of psoriatic epidermis and microvessels to treatment with topical steroids and oral methotrexate.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Biopsy; Female; Humans; Male; Methotrexate; Microcirculation; Microscopy, Electron; Middle Aged; Psoriasis; Skin; Triamcinolone Acetonide | 1985 |
Study of psoriatic epidermal cell kinetics and cell death after oral methotrexate.
Topics: Cell Survival; DNA Replication; Humans; Kinetics; Methotrexate; Mitosis; Psoriasis; Skin | 1985 |
Chromosomal study of patients with psoriasis treated with amethopterin.
Topics: Adolescent; Adult; Aged; Chromosomes; Genetics, Medical; Humans; Karyotyping; Leukocytes; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
Liver biopsy in methotrexate treatment.
Topics: Adult; Aged; Alanine Transaminase; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Necrosis; Pityriasis; Pityriasis Rubra Pilaris; Psoriasis | 1971 |
Talking turkey.
Topics: Animals; Diet Therapy; Food Analysis; Humans; Methotrexate; Prednisone; Psoriasis; Remission, Spontaneous; Triamcinolone; Tryptophan; Turkeys | 1971 |
Pustulosis palmaris et plantaris treated with methotrexate.
Topics: Erythema; Fever; Foot Dermatoses; Hand Dermatoses; Humans; Methotrexate; Nausea; Psoriasis; Skin; Stomatitis, Aphthous; Time Factors | 1971 |
[Trial of a new antimitotic agent in the treatment of psoriasis: bleomyoin].
Topics: Aged; Antibiotics, Antineoplastic; Bleomycin; Humans; Infusions, Parenteral; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Psoriasis | 1971 |
Induction of respiration-deficient yeast by methotrexate and its relevance for the antipsoriatic effect.
Topics: Cell Division; Cells, Cultured; Depression, Chemical; Growth; Methotrexate; Mitochondria; Mutation; Oxygen Consumption; Psoriasis; Saccharomyces cerevisiae; Spectrophotometry; Stimulation, Chemical; Time Factors; Yeast, Dried | 1973 |
[Use of cytostatic preparations in certain severe dermatoses (psoriasis, pemphigus, hemodermia)].
Topics: Alkylating Agents; Aminopterin; Antineoplastic Agents; Drug Therapy, Combination; Female; Flavonoids; Humans; Male; Methotrexate; Pemphigus; Prednisolone; Psoriasis | 1974 |
Cutaneous uses of the antiproliferative drugs.
Topics: Administration, Topical; Antimetabolites; Azauridine; Bleomycin; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Humans; Hydroxyurea; Immunotherapy; Melanoma; Methotrexate; Mitosis; Mycosis Fungoides; Organ Specificity; Psoriasis; Skin Neoplasms | 1974 |
Glucose-6-phosphate dehydrogenase in the blood of psoriatics, and the effects of methotrexate.
Topics: Dermatitis, Atopic; Enzyme Repression; Female; Glucosephosphate Dehydrogenase; Humans; Male; Methotrexate; Mycosis Fungoides; NAD; NADP; Psoriasis; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
The estimation of enzyme activity in living epidermal cells.
Topics: Animals; Aspartate Aminotransferases; Chemistry Techniques, Analytical; Cytoplasm; Epithelial Cells; Epithelium; Forearm; Glycolysis; Guinea Pigs; Humans; In Vitro Techniques; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Malates; Methotrexate; Mitochondria; NAD; NADP; Ouabain; Oxygen; Prednisolone; Psoriasis; Pyruvate Kinase; Skin; Spectrophotometry | 1974 |
Some aspects of the use of cytostatic drugs in dermatology.
Topics: Colchicine; Dactinomycin; Fluorouracil; Humans; Melanoma; Methotrexate; Mycosis Fungoides; Nitrogen Mustard Compounds; Psoriasis; Sarcoma, Kaposi; Skin Neoplasms; Vinblastine | 1966 |
Methotrexate in psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Methotrexate; Psoriasis | 1967 |
Methotrexate in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1968 |
Parenteral methotrexate for psoriasis.
Topics: Humans; Injections; Methotrexate; Psoriasis | 1968 |
Methotrexate in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1968 |
Methotrexate in psoriasis.
Topics: Female; Humans; Male; Methotrexate; Psoriasis | 1968 |
Methotrexate in psoriasis.
Topics: Adult; Female; Humans; Methandrostenolone; Methotrexate; Prednisolone; Psoriasis | 1968 |
[Analysis of serum proteins among psoriatics during methotrexate therapy].
Topics: Alpha-Globulins; Aminopterin; Beta-Globulins; Blood Protein Electrophoresis; Ceruloplasmin; Humans; Immunoelectrophoresis; Methotrexate; Psoriasis | 1968 |
Methotrexate and smallpox vaccination.
Topics: Ampicillin; Female; gamma-Globulins; Humans; Methotrexate; Middle Aged; Psoriasis; Smallpox Vaccine; Tetracycline; Vaccinia | 1968 |
Methotrexate in psoriasis.
Topics: Humans; Male; Methotrexate; Middle Aged; Pleurisy; Pneumonia; Psoriasis; Pulmonary Edema; Pulmonary Embolism | 1968 |
Methotrexate in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1968 |
The biology of psoriasis. An experimental study of the Koebner phenomenon.
Topics: Adolescent; Adult; Antimycin A; Colchicine; Cold Temperature; Enzymes; Female; Hot Temperature; Humans; Lidocaine; Male; Methotrexate; Middle Aged; Psoriasis; Skin | 1969 |
[Letter: Methotrexate in psoriasis].
Topics: Humans; Long-Term Care; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
[Clinicopathological conference: No 14-Spreading of redness and scaliness of the skin from the knees to the whole body].
Topics: Child; Humans; Male; Methotrexate; Psoriasis | 1974 |
[Effects and side-effects of immunosuppressive therapy in various dermatoses (author's transl)].
Topics: Dermatomyositis; Female; Hematopoietic System; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Male; Methotrexate; Pemphigus; Pregnancy; Psoriasis; Purines; Skin Diseases | 1974 |
[Liver biopsy studies in long-term therapy of psoriasis using methotrexate].
Topics: Adult; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Long-Term Care; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1974 |
Circulatory studies in inflammatory dermatoses. General and regional studies.
Topics: Adrenal Cortex Hormones; Aged; Blood Flow Velocity; Cardiac Output; Coal Tar; Dermatitis, Exfoliative; Female; Forearm; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Regional Blood Flow; Skin; Ultraviolet Rays | 1966 |
[Methotrexate therapy of dermatoses].
Topics: Adult; Dermatitis, Exfoliative; Female; Humans; Hyperplasia; Lymphatic Diseases; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Psoriasis; Skin Neoplasms; Steroids | 1966 |
Erythrodermic psoriasis in childhood. A young Negro child treated with methotrexate.
Topics: Black People; Dermatitis, Exfoliative; Humans; Infant; Injections, Intravenous; Male; Methotrexate; Psoriasis | 1968 |
[The use of methotrexate in dermatology. Indications and collateral effects].
Topics: Adult; Aged; Dermatitis, Exfoliative; Humans; Methotrexate; Middle Aged; Psoriasis; Skin Diseases | 1967 |
Treatment of psoriasis with minute divided oral doses of methotrexate.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Arthritis; Aspartate Aminotransferases; Cardiac Output; Dermatitis, Exfoliative; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1969 |
Parenteral methotrexate in psoriasis. A report on the efficacy and toxicity of long-term intermittent treatment.
Topics: Adult; Alkaline Phosphatase; Arthritis; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Diarrhea; Drug Eruptions; Female; Gastrointestinal Hemorrhage; Humans; Infusions, Parenteral; Intestinal Absorption; Liver Cirrhosis; Male; Methotrexate; Nausea; Psoriasis; Stomatitis, Aphthous; Time Factors | 1969 |
[Erythrodermia, pustulal psoriasis, rheumatic state in a ten-year-old child. Successful effect of the combination of antibio-corticotherapy and methotrexate].
Topics: Anti-Bacterial Agents; Child; Dermatitis, Exfoliative; Humans; Male; Methotrexate; Psoriasis; Rheumatic Diseases; Triamcinolone | 1970 |
[Methotrexate in psoriasis. Preliminary work: 10 cases)].
Topics: Adult; Aged; Dermatitis, Exfoliative; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
[Our experience with methotrexate in the treatment of psoriasis].
Topics: Adult; Aged; Dermatitis, Exfoliative; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
The application of an in vitro technique to the study of epidermal replication and metabolism.
Topics: Culture Techniques; DNA; Folic Acid Antagonists; Growth Inhibitors; Histidine; Humans; Methods; Methotrexate; Nucleosides; Proline; Protein Biosynthesis; Psoriasis; RNA; Skin; Thymidine; Tritium | 1971 |
Erythrodermic psoriasis with corneal ulcers and ophthalmological sequelae.
Topics: Adult; Beds; Corneal Ulcer; Dermatitis, Exfoliative; Female; Humans; Methotrexate; Panophthalmitis; Prednisolone; Psoriasis | 1971 |
[Limitations and risks of therapy of psoriasis with amethopterin and hydroxyurea].
Topics: Adult; Aged; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Drug Eruptions; Female; Gastrointestinal Diseases; Hematopoietic System; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis; Pyelonephritis | 1971 |
[Recent progress in American dermatology].
Topics: Adult; Carcinoma, Basal Cell; Child; Child, Preschool; Dermatitis; Dermatitis, Contact; Dermatomycoses; Drug Eruptions; Female; Gonorrhea; Humans; Infant; Keratosis; Lupus Erythematosus, Systemic; Male; Melanoma; Methotrexate; Pemphigus; Psoriasis; Research; Rothmund-Thomson Syndrome; Sarcoidosis; Skin Diseases; Skin Neoplasms; United States | 1972 |
[Damage due to treatment of psoriasis with folic acid antagonists].
Topics: Anemia, Hypochromic; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Drug Eruptions; Folic Acid Antagonists; Headache; Humans; Leucovorin; Methotrexate; Mouth Diseases; Mouth Mucosa; Nausea; Psoriasis; Vertigo | 1972 |
Pustular psoriasis and arthritis in congenital psoriasiform erythroderma.
Topics: Administration, Oral; Arthritis; Biopsy; Cervical Vertebrae; Child; Child, Preschool; Dermatitis, Exfoliative; Hand; Humans; Infant; Infant, Newborn; Male; Methotrexate; Psoriasis; Radiography; Skin; Suppuration | 1972 |
[Malignant reticulosis with Sezary's cells and psoriasis].
Topics: Aged; Chlorambucil; Dermatitis, Exfoliative; Diagnosis, Differential; Edema; Foot Dermatoses; Hand Dermatoses; Humans; Keratosis; Lymphatic Diseases; Male; Methotrexate; Prednisone; Pruritus; Psoriasis | 1971 |
[Problems of chronic skin diseases].
Topics: Adrenal Cortex Hormones; Ambulatory Care; Chronic Disease; Dermatitis Herpetiformis; Dermatitis, Exfoliative; Drug Eruptions; Humans; Lupus Vulgaris; Methotrexate; Pemphigus; Psoriasis; Skin Diseases | 1973 |
Treatment of skin diseases: recent trends.
Topics: Acne Vulgaris; Female; Humans; Male; Methotrexate; Psoriasis; Skin Diseases; Vitamin A; Vitiligo | 1973 |
Methotrexate. Effects on the enzymes of carbohydrate metabolism in psoriasis.
Topics: Aged; Carbohydrate Metabolism; Female; Fructose-Bisphosphate Aldolase; Humans; Ligases; Male; Methotrexate; Middle Aged; Oxidoreductases; Phosphoglucomutase; Phosphoric Monoester Hydrolases; Phosphotransferases; Psoriasis; Skin | 1967 |
Systemic corticosteroids and folic acid antagonists in the treatment of generalized pustular psoriasis. Evaluation and prognosis based on the study of 104 cases.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Betamethasone; Dexamethasone; Female; Folic Acid Antagonists; Humans; Hydrocortisone; Male; Methotrexate; Middle Aged; Paramethasone; Prednisolone; Prognosis; Psoriasis; Triamcinolone | 1969 |
Papular mucinosis in chronic psoriatic erythroderma. Report of a case.
Topics: Adrenocorticotropic Hormone; Adult; Antimetabolites; Coal Tar; Dermatitis, Exfoliative; Glucocorticoids; Humans; Hydrocortisone; Male; Mercaptopurine; Methotrexate; Mouth Diseases; Oral Manifestations; Prednisolone; Psoriasis; Sepsis; Skin Diseases; Ulcer | 1970 |
Metabolic and ultrastructural studies in a patient with pustular psoriasis (von Zumbusch).
Topics: Adrenal Cortex Hormones; Blood Protein Disorders; Capillaries; Colchicine; Epithelial Cells; Estrogens, Conjugated (USP); Female; Humans; Hydroxyurea; Hypocalcemia; Iodoquinol; Leukocytes; Methotrexate; Microcirculation; Microscopy, Electron; Middle Aged; Psoriasis; Serum Albumin; Skin; Tetracycline | 1972 |
[Experience in using immunosuppressive-cytostatics in the treatment of psoriasis].
Topics: Adult; Aged; Azathioprine; Female; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Psoriasis | 1974 |
[Pathogenesis of psoriasis and current therapeutic possibilities].
Topics: Adolescent; Adult; Coal Tar; Humans; Infant, Newborn; Metabolic Diseases; Methotrexate; Psoriasis; Sunlight | 1974 |
Liver disease in psoriatics--An effect of methotrexate therapy?
Topics: Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Infant; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methods; Methotrexate; Mitochondria, Liver; Psoriasis; Sulfobromophthalein; Time Factors | 1974 |
Effects of methotrexate and hydroxyurea on psoriatic epidermis. Preferential cytotoxic effects on psoriatic epidermis.
Topics: Administration, Oral; Administration, Topical; Biopsy; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Methotrexate; Prednisone; Psoriasis; Skin; Triamcinolone Acetonide | 1974 |
Treatment of psoriatic arthropathy with either azathioprine or methotrexate.
Topics: Adult; Arthritis; Azathioprine; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
[Clinico-biochemical parallels in the treatment of psoriasis with small doses of methotrexate].
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Ceruloplasmin; Drug Evaluation; Female; Haptoglobins; Humans; Leukocytes; Lipoproteins; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
[Clinical use of methotrexate in psoriasis].
Topics: Adolescent; Adult; Child; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
[Experiences with combined long term therapy of psoriasis arthropathica using antimetabolites and steroids].
Topics: Adult; Aged; Arthritis; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors; Triamcinolone | 1974 |
[Methotrexate treatment of psoriasis].
Topics: Humans; Methotrexate; Psoriasis | 1974 |
[Treatment of psoriasis with small doses of methotrexate].
Topics: Adolescent; Adult; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1974 |
Comparative studies of rubella antibodies in psoriatic patients treated with methotrexate.
Topics: Antibodies; Antigens; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Rubella; Rubella Vaccine | 1974 |
[Letter: Inverse psoriasis].
Topics: Female; Fumarates; Humans; Methotrexate; Middle Aged; Psoriasis; Vitamin A | 1974 |
Alcohol consumption in psoriasis.
Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Alcoholism; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Sex Factors | 1974 |
Pseudoleukemia during recovery from methotrexate toxicity in psoriasis.
Topics: Adult; Female; Hematologic Diseases; Humans; Leukemia; Methotrexate; Psoriasis | 1972 |
Severe liver damage caused by treatment of psoriasis with methotrexate.
Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Psoriasis | 1973 |
On methotrexate treatment of psoriasis. Model of a cytostatics treatment.
Topics: Age Factors; Alopecia; Atrophy; Carcinoma, Basal Cell; Diarrhea; Gastritis; Gastrointestinal Hemorrhage; Gingival Diseases; Gingivitis, Necrotizing Ulcerative; Humans; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Infections; Inflammation; Methotrexate; Nausea; Psoriasis; Skin Neoplasms; Stomatitis, Aphthous | 1972 |
[Lymphoreticular hyperplasia in a case of psoriasis treated with methotrexate for three years].
Topics: Biopsy; Fever; Humans; Lymph Nodes; Lymphoma, Follicular; Male; Methotrexate; Middle Aged; Prednisone; Psoriasis | 1972 |
Alterations of cell surfaces as a pathogenetic factor in psoriasis. Possible loss of contact inhibition of growth.
Topics: Adrenal Cortex Hormones; Biopsy; Cell Adhesion; Cell Membrane; Contact Inhibition; Cytological Techniques; Desmosomes; Extracellular Space; Glycoproteins; Histocytochemistry; Humans; Methotrexate; Microscopy, Electron; Mitosis; Psoriasis; Skin | 1973 |
[Proceedings: Immunosuppression and treatment of psoriasis using cytostatic agents].
Topics: Aged; Antineoplastic Agents; Azathioprine; Bibliographies as Topic; Chemical and Drug Induced Liver Injury; Humans; Hydroxyurea; Immunosuppression Therapy; Male; Methotrexate; Psoriasis | 1973 |
Psoriasis: its nature and treatment.
Topics: Adrenal Cortex Hormones; Aminopterin; Australia; Betamethasone; Diet; Europe; Humans; Methotrexate; Psoriasis; Skin; Triamcinolone Acetonide; Ultraviolet Rays; United Kingdom; United States | 1972 |
Long-term effects of hydroxyurea in psoriases.
Topics: Adult; Aged; Biopsy; Erythrocytes, Abnormal; Female; Hemoglobinometry; Humans; Hydroxyurea; Leukocyte Count; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1972 |
Structural and functional abnormalities of the liver in psoriasis before and during methotrexate therapy.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis | 1972 |
[Use of methotrexate in the treatment of patients with psoriasis under ambulatory conditions].
Topics: Adolescent; Adult; Ambulatory Care; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Annulus migrans. Identical lesions in pustular psoriasis, Reiter's syndrome, and geographic tongue.
Topics: Acrodermatitis; Adult; Aged; Arthritis, Reactive; Cheek; Female; Humans; Male; Methotrexate; Middle Aged; Mouth Mucosa; Pityriasis; Pityriasis Rubra Pilaris; Psoriasis; Terminology as Topic; Tongue Diseases | 1973 |
[Therapy of psoriasis with methotrexate. Report on 6 selected cases].
Topics: Adult; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1973 |
Combined methotrexate and hydroxyurea therapy for psoriasis.
Topics: Administration, Oral; Adult; Arthritis; Drug Hypersensitivity; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1973 |
[Psoriasis-cytostatic treatment with amethopterin (methotrexate)].
Topics: Biopsy; Female; Humans; Liver; Male; Methotrexate; Psoriasis | 1973 |
Pustular psoriasis of Zumbusch, generalized.
Topics: Adult; Humans; Male; Methotrexate; Psoriasis | 1973 |
[Treatment of psoriasis with methotrexate].
Topics: Drug Resistance; Humans; Methotrexate; Psoriasis | 1973 |
Generalized pustular psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Hydroxyurea; Methotrexate; Psoriasis | 1973 |
[Incidence of liver diseases in psoriatic patients with special reference to methotrexate therapy].
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1973 |
The clinical use of immunosuppressive drugs.
Topics: Adrenal Cortex Hormones; Aged; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Infections; Male; Methotrexate; Pregnancy; Psoriasis | 1973 |
[Methotrexate treatment of psoriasis in combination with pyrogenal, calcium pangamate and chelatones].
Topics: Adult; Chelating Agents; Humans; Methotrexate; Middle Aged; Psoriasis; Pyrogens; Vitamin B Complex | 1973 |
[Effectiveness and complications of treating psoriasis with antimetabolites].
Topics: Adrenal Cortex Hormones; Adult; Antimetabolites; Chronic Disease; Drug Combinations; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Psoriasis; Recurrence; Remission, Spontaneous | 1973 |
Methrotrexate U.S.P. (amethopterin) and methotrexate sodium.
Topics: Abortion, Induced; Anemia; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Choriocarcinoma; Drug Interactions; Female; Humans; Leukemia; Leukopenia; Male; Methotrexate; Neoplasms; Pregnancy; Psoriasis; Skin Diseases; Testicular Neoplasms; Thrombocytopenia; Uric Acid; Uterine Neoplasms | 1973 |
Methotrexate therapy for psoriasis. Guideline revisions.
Topics: Administration, Oral; Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Psoriasis | 1973 |
Psoriasis-liver-methotrexate interactions.
Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Alanine Transaminase; Alcohol Drinking; Alkaline Phosphatase; Aspartate Aminotransferases; Biopsy; Diabetes Complications; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Sex Factors; Sulfobromophthalein; Time Factors | 1973 |
Liver biopsy in psoriasis. A controlled study.
Topics: Administration, Oral; Alcoholism; Biopsy; Fatty Liver; Humans; Injections; Liver; Methotrexate; Psoriasis | 1973 |
[Methotrexate in the therapy of psoriasis].
Topics: Fever; Gastrointestinal Diseases; Humans; Methotrexate; Psoriasis; Thrombocytopenia | 1973 |
[Liver of psoriatic patients treated with methotrexate].
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis | 1973 |
Liver ultrastructure in methotrexate treatment of psoriasis.
Topics: Adult; Aged; Biopsy, Needle; Female; Humans; Liver; Male; Methotrexate; Microscopy, Electron; Middle Aged; Psoriasis | 1973 |
Psoriasis: practical therapeutic perspectives.
Topics: Adrenal Cortex Hormones; Dermatologic Agents; Emulsions; Humans; Methotrexate; Psoriasis; Tars; Ultraviolet Therapy | 1973 |
Psoriatic arthritis.
Topics: Arthritis; Aspirin; Glucocorticoids; Gold; Humans; Methotrexate; Psoriasis | 1973 |
Methotrexate for psoriasis.
Topics: DNA; Folic Acid Antagonists; Humans; Liver; Liver Function Tests; Methotrexate; Psoriasis; Retrospective Studies; Time Factors | 1973 |
Cirrhosis following methotrexate administration for psoriasis.
Topics: Female; Humans; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis | 1973 |
[Methotrexate in the treatment of various forms of psoriasis].
Topics: Adult; Chronic Disease; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Tablets | 1973 |
Liver injury associated with methotrexate therapy for psoriasis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis; Time Factors | 1973 |
Hepatotoxicity of methotrexate in the treatment of psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1973 |
[Paradoxical reaction of peripheral blood in the treatment of psoriasis with methotrexate].
Topics: Adult; Humans; Leukocytosis; Male; Methotrexate; Psoriasis | 1973 |
[Psoriasis vulgaris--catamnesis and climate therapy of the North Sea].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arsenic; Bathing Beaches; Climate; Climatotherapy; Evaluation Studies as Topic; Female; Germany, East; Health Resorts; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Seawater; State Medicine; Sunlight | 1973 |
[Effectiveness and side effects of the treatment of certain dermatoses with methotrexate].
Topics: Adolescent; Adult; Aged; Dermatomycoses; Female; Humans; Male; Methotrexate; Middle Aged; Pemphigus; Psoriasis; Sarcoma, Kaposi; Skin Diseases; Skin Neoplasms | 1973 |
Hepatotoxicity of long-term methotrexate therapy for psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Time Factors | 1973 |
[The effect of cytostatic drugs on the healthy and diseased skin].
Topics: Humans; Methotrexate; Psoriasis; Skin | 1973 |
Letter: Methotrexate dosage schedule.
Topics: Administration, Oral; Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis | 1974 |
[Oral therapy of psoriasis using methotrexate].
Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Humans; Methotrexate; Middle Aged; Psoriasis | 1974 |
Jaundice in acute pustular psoriasis.
Topics: Arthropathy, Neurogenic; Bilirubin; Chemical and Drug Induced Liver Injury; Clindamycin; Female; Fusidic Acid; Humans; Jaundice; Leukocytosis; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1974 |
Effects of methotrexate on the liver in psoriasis.
Topics: Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Necrosis; Psoriasis; Sulfobromophthalein | 1974 |
Carcinoma in situ of the cervix after amethopterin therapy.
Topics: Adult; Carcinoma in Situ; Female; Humans; Methotrexate; Psoriasis; Uterine Cervical Neoplasms; Vaginal Smears | 1974 |
Methotrexate induced liver disease in psoriasis.
Topics: Administration, Oral; Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Diabetes Complications; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1974 |
Intermittent positive-pressure ventilation in chicken-pox pneumonitis.
Topics: Adult; Chickenpox; Eczema; Female; Humans; Methotrexate; Pneumonia, Viral; Positive-Pressure Respiration; Prednisolone; Psoriasis; Respiratory Insufficiency | 1969 |
Treatment of severe generalized psoriasis with oral methotrexate. (A case report).
Topics: Blood Cell Count; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
[Methotrexate in Psoriasis vulgaris].
Topics: Adolescent; Female; Hospitalization; Humans; Long-Term Care; Methotrexate; Psoriasis | 1971 |
[Preliminary studies on immunosuppressive therapy of connective tissue disorders].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Cyclophosphamide; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Methotrexate; Nephrotic Syndrome; Psoriasis | 1970 |
[Systemic administration of vitamin A megadoses in psoriasis].
Topics: Administration, Oral; Adolescent; Adult; Aspartate Aminotransferases; Emulsions; Female; Humans; Liver; Long-Term Care; Male; Methotrexate; Middle Aged; Psoriasis; Remission, Spontaneous; Thymol; Vitamin A | 1971 |
[Lymphoreticular hyperplasia under 3-year methotrexate treatment for psoriasis].
Topics: Humans; Hyperplasia; Long-Term Care; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Psoriasis; Remission, Spontaneous | 1971 |
Generalized pustular psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Methotrexate; Psoriasis; Sepsis | 1972 |
Generalized pustular psoriasis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Humans; Methotrexate; Psoriasis; Sepsis | 1972 |
Drugs and their use.
Topics: Drug and Narcotic Control; Ethics, Medical; Humans; Malpractice; Methotrexate; Psoriasis | 1972 |
Use of methotrexate in psoriasis.
Topics: Biopsy; Blood Cell Count; Chemical and Drug Induced Liver Injury; Female; Hemoglobinometry; Humans; Kidney Function Tests; Liver; Liver Function Tests; Male; Methotrexate; Pregnancy; Psoriasis | 1972 |
Generalized pustular psoriasis.
Topics: Cephaloridine; Cloxacillin; Humans; Methotrexate; Psoriasis | 1972 |
Methotrexate hepatotoxicity in psoriasis--comparison of different dose regimens.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Congenital psoriasis: report of three cases.
Topics: Adolescent; Arthritis; Biopsy; Child; Female; Humans; Infant; Male; Methotrexate; Psoriasis | 1972 |
Methotrexate hepatotoxicity in psoriasis.
Topics: Alcohol Drinking; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1972 |
Cirrhosis following prolonged treatment of psoriasis with methotrexate orally.
Topics: Administration, Oral; Biopsy; Cell Nucleus; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Liver Regeneration; Methotrexate; Middle Aged; Psoriasis | 1972 |
[Changes of serum phosphoglycoisomerase during psoriasis therapy using Methotrexate].
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Glucose-6-Phosphate Isomerase; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
[Methotrexate therapy in psoriasis].
Topics: Humans; Methotrexate; Nausea; Psoriasis | 1972 |
Selective action of methotrexate on psoriatic epidermal cells.
Topics: Biopsy; DNA Replication; Humans; Methotrexate; Mitosis; Psoriasis; Skin; Thymidine; Time Factors; Tritium | 1972 |
[Treatment of psoriasis with human leukocyte interferon and interferon combined with deoxyribonuclease and cytostatics (preliminary report)].
Topics: Adolescent; Adult; Child; Deoxyribonucleases; Female; Humans; Interferons; Leukocytes; Male; Mercaptopurine; Methotrexate; Psoriasis | 1972 |
Methotrexate-associated liver disease in psoriatic patients.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies | 1972 |
Absorption and local action of methotrexate in human and mouse skin.
Topics: Administration, Oral; Animals; Aspartate Aminotransferases; Cell Division; Female; Humans; Injections; Male; Methotrexate; Mice; Mice, Inbred Strains; Ointments; Psoriasis; Remission, Spontaneous; Skin; Skin Absorption | 1972 |
Generalized pustular psoriasis.
Topics: Humans; Methotrexate; Psoriasis; Steroids | 1972 |
Abscess formation in a Rathke's cleft cyst. Case report.
Topics: Brain Abscess; Female; Humans; Hypopituitarism; Immunosuppression Therapy; Methotrexate; Middle Aged; Pituitary Diseases; Pituitary Gland; Psoriasis; Sella Turcica; Staphylococcal Infections | 1972 |
Psoriasis, methotrexate, and cancer.
Topics: Aged; Breast Neoplasms; Humans; Kidney Neoplasms; Male; Methotrexate; Psoriasis; Time Factors | 1972 |
[Treatment of psoriasis with hydroxyurea].
Topics: Adult; Aged; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
[On special methods of use of folic acid antagonists in psoriasis].
Topics: Adolescent; Adult; Aged; Evaluation Studies as Topic; Female; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1972 |
Deficient folate activity during treatment of psoriasis with methotrexate diagnosed by determination of serine synthesis in lymphocytes.
Topics: Adult; Aged; Carbon Isotopes; Female; Folic Acid Deficiency; Formates; Humans; In Vitro Techniques; Intestinal Absorption; Lymphocytes; Male; Methotrexate; Middle Aged; Psoriasis; RNA; Serine; Vitamin B 12 | 1972 |
Methotrexate in young women with psoriasis.
Topics: Abnormalities, Drug-Induced; Adult; Female; Fetus; Humans; Infant, Newborn; Methotrexate; Pregnancy; Psoriasis | 1971 |
Liver damage and methotrexate.
Topics: Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis | 1971 |
[Treatment of psoriasis by antimetabolites, especially methotrexate].
Topics: Antimetabolites; Humans; Methotrexate; Psoriasis | 1971 |
Methotrexate. Mechanism of action on DNA synthesis in psoriasis.
Topics: Autoradiography; Biopsy; Deoxyuridine; Depression, Chemical; DNA Replication; Humans; Injections, Intradermal; Injections, Intramuscular; Methotrexate; Psoriasis; Skin; Tritium | 1971 |
[Treatment of arthropathic psoriasis with antimetabolites and glucocorticoids].
Topics: Adult; Aged; Arthritis; Chronic Disease; Drug Synergism; Female; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1971 |
[Treatment of psoriasis with methotrexate].
Topics: Humans; Methotrexate; Psoriasis; Time Factors | 1971 |
Blood levels of methotreate and the treatment of psoriasis.
Topics: Administration, Oral; Fluorometry; Humans; Injections, Intramuscular; Injections, Spinal; Intestinal Absorption; Methotrexate; Psoriasis | 1971 |
Pulmonary and hepatic complications of methotrexate therapy of psoriasis.
Topics: Administration, Oral; Biopsy; Chemical and Drug Induced Liver Injury; Dyspnea; Humans; Lung Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Radiography; Time Factors | 1971 |
Methotrexate and hepatic disease.
Topics: Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis | 1971 |
[Study of the seminal fluid in subjects treated with methotrexate].
Topics: Adult; Humans; Male; Methotrexate; Psoriasis; Semen; Spermatozoa | 1971 |
Human mitotic and meiotic chromosome damage following in vivo exposure to methotrexate.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Fibroblasts; Humans; Lymphocytes; Male; Meiosis; Methotrexate; Microscopy, Polarization; Mitosis; Psoriasis; Testis | 1971 |
Pustular psoriasis.
Topics: Aged; Humans; Male; Methotrexate; Psoriasis; Suppuration | 1971 |
[Unusual micromaculous melanoderma developing in patients with psoriatic erythroderma during methotrexate therapy].
Topics: Adult; Humans; Male; Melanosis; Methotrexate; Pigmentation; Psoriasis | 1971 |
Hepatic structure and function in psoriasis before and after treatment with methotrexate.
Topics: Biopsy; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Prospective Studies; Psoriasis; Sulfobromophthalein | 1971 |
Methotrexate-induced congenital malformations.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Methotrexate; Pregnancy; Pregnancy Complications, Infectious; Psoriasis; Skull | 1971 |
The prognosis of generalized pustular psoriasis.
Topics: Acrodermatitis; Acute Disease; Follow-Up Studies; Foot; Hand; Humans; Methotrexate; Prognosis; Psoriasis; Steroids | 1971 |
Psoriasis, methotrexate and tuberculosis.
Topics: Humans; Male; Methotrexate; Middle Aged; Psoriasis; Tuberculosis | 1971 |
[Dermatologic topical treatment. 5. Psoriasis].
Topics: Anthracenes; Humans; Methotrexate; Ointments; Psoriasis; Pyrroles; Steroids; Ultraviolet Therapy | 1971 |
[Ambulant treatment of psoriasis with methotrexate].
Topics: Ambulatory Care; Humans; Methotrexate; Psoriasis | 1971 |
[Liver changes in psoriasis vulgaris].
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein | 1971 |
Reticulosis as a long-term side-effect of methotrexate therapy in a patient with generalized psoriasis and psoriatic arthritis.
Topics: Arthritis; Humans; Hyperplasia; Immunosuppressive Agents; Lymphatic Diseases; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Organothiophosphorus Compounds; Psoriasis | 1971 |
Syndrome of unilateral ectromelia, psoriasis and central nervous system anomalies.
Topics: Abnormalities, Multiple; Autoradiography; Birth Weight; Cell Division; Central Nervous System; DNA; Ectromelia; Female; Functional Laterality; Genes, Dominant; Humans; Infant; Male; Methotrexate; Musculoskeletal Abnormalities; Pedigree; Psoriasis; Skin; Syndrome; Thymidine; Tritium | 1971 |
The use of methotrexate in the treatment of psoriasis.
Topics: Adolescent; Adult; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
[Treatment of psoriasis with methotrexate].
Topics: Adolescent; Adult; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
Folate-dependent enzymes in human epidermis. Tetrahydrofolate-dependent enzymes and relationship between dihydrofolic reductase and amethopterin.
Topics: Aminohydrolases; Carcinoma, Squamous Cell; Humans; Methotrexate; Oxidoreductases; Psoriasis; Skin; Skin Neoplasms; Tetrahydrofolate Dehydrogenase; Transferases | 1967 |
[Therapeutic experiments with antimetabolites of folic acid in the cure of psoriasis].
Topics: Adolescent; Adult; Aminopterin; Child; Epithelium; Female; Humans; Injections, Intravenous; Leukocyte Count; Leukocytes; Male; Methotrexate; Middle Aged; Mitosis; Psoriasis; Tetrahydrofolate Dehydrogenase | 1967 |
Biochemical and pathophysiological rationale for amethopterin in psoriasis.
Topics: Administration, Oral; Autoradiography; Deoxyuridine; Epithelium; Germ Cells; Humans; Injections, Intramuscular; Methotrexate; Mitosis; Psoriasis; Skin; Thymidine; Time Factors; Tritium | 1971 |
Failure of leucovorin "rescue" in methotrexate treatment of psoriasis.
Topics: Humans; Leucovorin; Methotrexate; Psoriasis | 1970 |
Methotrexate and the citrovorum factor in the treatment of psoriasis.
Topics: Aged; Humans; Leucovorin; Methotrexate; Middle Aged; Psoriasis | 1970 |
Hazards of prolonged low-dose methotrexate therapy.
Topics: Adult; Anemia, Aplastic; Blood Cell Count; Chemical and Drug Induced Liver Injury; Hepatomegaly; Humans; Leucovorin; Liver; Liver Function Tests; Male; Methotrexate; Psoriasis; Splenomegaly; Time Factors | 1970 |
Cirrhosis caused by methotrexate in the treatment of psoriasis.
Topics: Adult; Biopsy; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1969 |
Cirrhosis following methotrexate administration for psoriasis.
Topics: Bilirubin; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1969 |
Methotrexate for psoriasis--some impressions seven years later.
Topics: Humans; Methotrexate; Psoriasis | 1969 |
[Psoriasis. Treatment with methylaminopterin (Methotrexate) in weekly oral doses].
Topics: Adolescent; Adult; Aged; Blood; Chronic Disease; Female; Humans; Male; Methotrexate; Middle Aged; Nausea; Ointments; Psoriasis; Stomatitis; Time Factors | 1969 |
[A comparative evaluation of different methods of treatment of psoriasis].
Topics: Adolescent; Adult; Aged; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Sulfur; Tars; Triamcinolone | 1969 |
Cell proliferation kinetics in benign and malignant skin diseases in humans.
Topics: Autoradiography; Carcinoma, Basal Cell; Cell Division; DNA; DNA, Neoplasm; Humans; Ichthyosis; Injections, Intramuscular; Kinetics; Methotrexate; Mitosis; Psoriasis; Skin; Skin Diseases; Skin Neoplasms; Thymidine; Tritium | 1969 |
[Experience with methotrexate in the management of psoriasis].
Topics: Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous; Methotrexate; Nausea; Psoriasis; Thrombocytopenia; Time Factors | 1969 |
Methotrexate in psoriasis.
Topics: Adult; Humans; Methotrexate; Middle Aged; Psoriasis | 1969 |
Absorption of methotrexate and hepatotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Humans; Intestinal Absorption; Intestines; Methotrexate; Psoriasis | 1969 |
Methotrexate and psoriasis.
Topics: Coma; Humans; Methotrexate; Psoriasis; Respiratory Tract Diseases | 1969 |
[Methotrexate treatment of psoriasis].
Topics: Chromosome Aberrations; Chromosome Disorders; Folic Acid Antagonists; Humans; Methotrexate; Psoriasis | 1969 |
[72 cases of psoriasis treated by methotrexate].
Topics: Adolescent; Adult; Biopsy; Child; Female; Humans; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Thrombocytopenia | 1969 |
[Comparative study of the effect of the antimetabolic agent methotrexate in psoriasis, psoriatic arthropathy and rheumatoid arthritis].
Topics: Administration, Oral; Arthritis; Arthritis, Rheumatoid; Biopsy; Humans; Injections, Intravenous; Methotrexate; Psoriasis; Skin | 1969 |
Intermittent high dose oral methotrexate therapy in psoriasis.
Topics: Adult; Aged; Aspirin; Ataxia; Colitis; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Stevens-Johnson Syndrome; Time Factors; Vomiting | 1970 |
Monitoring methotrexate therapy in psoriasis.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Child; Cholesterol; Female; Humans; L-Lactate Dehydrogenase; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Uric Acid | 1970 |
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Papilloma; Pemphigus; Precancerous Conditions; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms; Virus Diseases | 1970 |
Methotrexate treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
Liver biopsy in psoriasis.
Topics: Adult; Aged; Alcoholism; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Transaminases | 1970 |
[A large pustular arthropathic psoriasis with coronary crisis].
Topics: Adult; Arthritis; Arthritis, Reactive; Coronary Disease; Diagnosis, Differential; Humans; Male; Methotrexate; Psoriasis | 1970 |
[Treatment of psoriasis in 1970].
Topics: Humans; Methotrexate; Psoriasis; Ultraviolet Therapy | 1970 |
[Methotrexate in the treatment of psoriasis].
Topics: Adult; Aged; Asthenia; Chemical and Drug Induced Liver Injury; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1970 |
Psoriasis, methotrexate, and cirrhosis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1970 |
[Chromosome study in patients with psoriasis treated with methotrexate].
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosome Mapping; Chromosomes; Humans; Methotrexate; Psoriasis | 1970 |
[Treatment of dermatologic lesions using immunosuppressive agents and cytostatics].
Topics: Antineoplastic Agents; Azathioprine; Dermatomyositis; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Pemphigus; Psoriasis; Scleroderma, Systemic; Skin Diseases; Skin Neoplasms | 1970 |
Methotrexate and psoriasis.
Topics: Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis; United States; United States Food and Drug Administration | 1970 |
[Methotrexate in the treatment of psoriasis. Clinico-therapeutic experiences].
Topics: Adult; Aged; Humans; Methotrexate; Middle Aged; Psoriasis | 1970 |
[Liver damage during methotrexate treatment of psoriasis].
Topics: Adult; Biopsy; Fatty Liver; Female; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors | 1970 |
Methotrexate for psoriasis in weekly oral doses without any adjunctive therapy.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Blood Cell Count; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
[Psoriasis. Cytotoxic treatment with oral methotrexate].
Topics: Administration, Oral; Age Factors; Female; Humans; Male; Methotrexate; Psoriasis; Time Factors | 1970 |
Pityriasis rubra pilaris vs psoriasis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Humans; Methotrexate; Pityriasis Rubra Pilaris; Psoriasis; Scalp Dermatoses | 1970 |
Liver disease associated with methotrexate treatment of psoriatic patients.
Topics: Adult; Alanine Transaminase; Aminopterin; Arthritis; Aspartate Aminotransferases; Blood Cell Count; Cell Division; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; DNA Replication; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein; Tetrahydrofolate Dehydrogenase | 1970 |
The effect of methotrexate, corticosteroids and azathioprine on fingernail growth in psoriasis.
Topics: Azathioprine; Humans; Methotrexate; Nails; Prednisone; Psoriasis | 1970 |
[Chromosome investigations in lymphocytes and bone marrow from long term methotrexate-treated psoriatics].
Topics: Adult; Aged; Arsenicals; Bone Marrow; Bone Marrow Cells; Chromosomes; Humans; Lymphocytes; Male; Methotrexate; Middle Aged; Mutation; Psoriasis | 1970 |
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Sulfobromophthalein | 1970 |
Psoriasis and systematized epidermal nevus.
Topics: Adult; Biopsy; Female; Humans; Japan; Keratosis; Methotrexate; Nerve Endings; Nevus; Psoriasis; Sensation; Skin; Skin Neoplasms; Wounds and Injuries | 1970 |
[Treatment of psoriasis with methotrexate].
Topics: Arthritis; Hematopoiesis; Humans; Kidney Function Tests; Liver; Liver Function Tests; Methotrexate; Psoriasis | 1970 |
[Andrologic examinations in the antimetabolite therapy of psoriasis].
Topics: Adult; Antimetabolites; Antineoplastic Agents; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Spermatozoa | 1970 |
[Immunosuppressive agents and cytogenetics].
Topics: Azathioprine; Chromosome Aberrations; Cytogenetics; Female; Humans; Immunosuppressive Agents; Leukemia, Radiation-Induced; Male; Meiosis; Methotrexate; Psoriasis | 1970 |
[Treatment of psoriasis with methotrexate. Preliminary note].
Topics: Aged; Humans; Male; Methotrexate; Psoriasis | 1970 |
[Our experience with methotrexate in psoriasis].
Topics: Adult; Female; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Psoriasis | 1970 |
[1st experiences with multiple stage cancer therapy of psoriatic patients].
Topics: Adolescent; Adult; Female; Hot Temperature; Humans; Male; Meprobamate; Methods; Methotrexate; Psoriasis | 1970 |
[Practical use of immunosuppressive drugs and cytostatics in dermatological diseases].
Topics: Animals; Guinea Pigs; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Methotrexate; Psoriasis; Skin Diseases; Skin Neoplasms | 1970 |
Methotrexate therapy--some cautions.
Topics: Antimetabolites; Choriocarcinoma; Female; Humans; Leukemia; Methotrexate; Pregnancy; Psoriasis | 1970 |
Methotrexate for psoriasis. A new therapeutic schedule.
Topics: Administration, Oral; Alopecia; Humans; Injections, Intramuscular; Leukopenia; Methotrexate; Mouth Diseases; Nausea; Prognosis; Psoriasis; Thrombocytopenia; Ulcer; Urticaria | 1971 |
Hepatotoxicity of methotrexate in the treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Alcoholism; Biopsy; Chemical and Drug Induced Liver Injury; Diabetes Complications; Female; Follow-Up Studies; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Obesity; Prospective Studies; Psoriasis; Retrospective Studies | 1971 |
Liver damage due to methotrexate in patients with psoriasis.
Topics: Adult; Aged; Biopsy; Cell Nucleus; Fatty Liver; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein | 1971 |
Suppression of an antibody to factor VIII by a combination of factor VIII and cyclophosphamide.
Topics: Antibodies; Antigen-Antibody Reactions; Antigens; Azathioprine; Blood Coagulation Disorders; Blood Coagulation Tests; Chromatography, Gel; Cyclophosphamide; Drug Synergism; Factor VIII; Female; Hematoma; Hemorrhage; Humans; Immune Tolerance; Immunoglobulin G; Immunosuppression Therapy; Melena; Methotrexate; Middle Aged; Precipitin Tests; Psoriasis; Respiratory Tract Infections; Triamcinolone | 1971 |
Psoriasis, methotrexate and tuberculosis.
Topics: Adult; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Radiography, Thoracic; Tuberculin Test; Tuberculosis | 1971 |
Azaribine in the treatment of psoriasis.
Topics: Chemical and Drug Induced Liver Injury; DNA; Humans; Methotrexate; Orotic Acid; Psoriasis; Time Factors; Triazines | 1971 |
[Methotrexate in the therapy of psoriasis].
Topics: Adult; Age Factors; Humans; Methotrexate; Middle Aged; Psoriasis | 1971 |
[Pustulous ppsoriasis].
Topics: Adult; Blister; Humans; Hydrocortisone; Hypocalcemia; Methotrexate; Psoriasis | 1971 |
[Apropos of 2 accidents during general treatments with methotrexate].
Topics: Aged; Chemical and Drug Induced Liver Injury; Dermatitis; Female; Humans; Hypothermia; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Psoriasis | 1971 |
Psoriasis in childhood.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatologic Agents; Female; Humans; Infant; Infections; Male; Methotrexate; Middle Aged; Psoriasis; Psychophysiologic Disorders; Racial Groups; Recurrence; Sex Factors; Skin; Skin Diseases, Infectious; Sunlight | 1971 |
Ichthyosis and methotrexate: a word of caution.
Topics: Adolescent; Child; Diagnosis, Differential; Female; Humans; Ichthyosis; Male; Methotrexate; Psoriasis | 1971 |
Malignancy during methotrexate and steroid therapy for psoriasis.
Topics: Adult; Carcinoma, Squamous Cell; Humans; Immunosuppression Therapy; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Prednisone; Psoriasis; Radiography; Skin Neoplasms | 1971 |
Methotrexate-induced carcinoma?
Topics: Carcinoma, Transitional Cell; Humans; Immunosuppression Therapy; Male; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Neoplasms; Psoriasis | 1971 |
Methotrexate, alcohol, and liver damage.
Topics: Administration, Oral; Alcoholic Intoxication; Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1971 |
Short-term observations in the use of intravenous methotrexate in the treatment of psoriasis.
Topics: Adult; Aged; Female; Humans; Injections, Intravenous; Male; Methotrexate; Middle Aged; Psoriasis | 1967 |
[Histological picture report No. 197. Psoriasis vulgaris of the vulva].
Topics: Adult; Female; Humans; Methotrexate; Neutrophils; Psoriasis; Triamcinolone; Vulvitis | 1967 |
[Current treatment of psoriasis. The proven and the new in the treatment of psoriasis].
Topics: Dermatologic Agents; Humans; Methotrexate; Psoriasis; Triamcinolone; Ultraviolet Therapy | 1967 |
Amethopterin (methotrexate) in connective tissue disease-psoriasis and polyarthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Mouth Diseases; Psoriasis; Ulcer | 1968 |
Experiences with methotrexate in psoriasis.
Topics: Adolescent; Adult; Bone Marrow; Female; Humans; Iron Isotopes; Male; Methotrexate; Middle Aged; Psoriasis; Skin | 1968 |
Radioactive iron studies in patients treated with methotrexate for psoriasis.
Topics: Bone Marrow; Erythrocytes; Erythropoiesis; Humans; Infusions, Parenteral; Iron; Iron Isotopes; Liver; Methotrexate; Psoriasis; Spleen | 1968 |
Methotrexate in psoriasis.
Topics: Adult; Aged; Female; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Nausea; Psoriasis | 1968 |
Light sensitive dermatitis.
Topics: Dermatitis; Humans; Male; Methotrexate; Middle Aged; Photosensitivity Disorders; Psoriasis; Radiation Effects; Skin | 1968 |
[Arthropathic pustulent psoriasis. Result of treatment with methotrexate].
Topics: Arthritis, Rheumatoid; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
Cirrhosis associated with methotrexate treatment of psoriasis.
Topics: Adult; Esophageal and Gastric Varices; Female; Folic Acid Antagonists; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
The nature of psoriasis.
Topics: DNA; Histocytochemistry; Humans; Hyperplasia; Methotrexate; Mitosis; Psoriasis; Skin | 1968 |
[Contribution to the therapy of psoriasis with methotrexate].
Topics: Adult; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1968 |
[Surprisingly rapid effect of methotrexate in the psoriasis of an 82-year-old patient with simultaneous side-effect in the eye].
Topics: Aged; Eye Diseases; Humans; Male; Methotrexate; Psoriasis; Time Factors | 1968 |
[Sodium amethopterin in psoriasis].
Topics: Humans; Methotrexate; Psoriasis | 1968 |
Methotrexate for psoriasis in weekly oral doses.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anemia; Aspartate Aminotransferases; Child; Female; Folic Acid Antagonists; Follow-Up Studies; Humans; Kidney Function Tests; Leukopenia; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1969 |
Reactivation of acute inflammation by methotrexate.
Topics: Erythema; Female; Humans; Inflammation; Male; Methotrexate; Photosensitivity Disorders; Psoriasis; Radiation Effects; Skin; Ultraviolet Rays | 1969 |
Methotrexate: a calculated risk.
Topics: Humans; Injections, Intravenous; Methotrexate; Psoriasis | 1969 |
Generalized pustular psoriasis.
Topics: Adrenal Cortex Hormones; Humans; Methotrexate; Psoriasis | 1969 |
Generalized pustular psoriasis.
Topics: Coal Tar; Female; Humans; Hypersensitivity; Methotrexate; Middle Aged; Ointments; Psoriasis | 1969 |
[Severe arthropathic and pustular psoriasis cleared up by methotrexate].
Topics: Adrenal Cortex Hormones; Adult; Arthritis; Candidiasis; Drug Synergism; Humans; Indomethacin; Male; Methotrexate; Nails; Psoriasis; Suppuration; Syphilis | 1969 |
Cirrhosis and methotrexate treatment of psoriasis.
Topics: Humans; Liver Cirrhosis; Methotrexate; Psoriasis | 1969 |
Methotrexate and psoriasis.
Topics: Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Humans; Liver Function Tests; Methotrexate; Psoriasis | 1969 |
Methotrexate.
Topics: Humans; Methotrexate; Psoriasis | 1969 |
Cytogenetic evaluation of methotrexate-treated psoriatic patients.
Topics: Adolescent; Adult; Chromatids; Chromosome Aberrations; Chromosomes; Culture Techniques; Female; Humans; Leukocytes; Male; Methotrexate; Middle Aged; Psoriasis | 1969 |
Site of action of methotrexate in psoriasis.
Topics: Adult; Aged; Child; Dimethyl Sulfoxide; Female; Humans; Injections, Intradermal; Male; Methotrexate; Middle Aged; Occlusive Dressings; Psoriasis; Tritium | 1969 |
Methotrexate for psoriasis. A preliminary report.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1965 |
Chromosomal abnormalities produced by folic acid antagonists.
Topics: Aminopterin; Chromosome Aberrations; Chromosome Disorders; Culture Techniques; Humans; Karyotyping; Lymphocytes; Methotrexate; Psoriasis | 1965 |
[Psoriasis and methotrexate].
Topics: Humans; Methotrexate; Psoriasis | 1965 |
Response of psoriatic arthropathy to methotrexate.
Topics: Adult; Aged; Arthritis; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1965 |
Management of psoriasis using methotrexate orally in a single weekly dose.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1966 |
The use of methotrexate in the management of psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1966 |
[Methotrexate therapy of psoriasis].
Topics: Humans; Methotrexate; Psoriasis | 1966 |
Methotrexate for psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1966 |
Action of methotrexate on skin and intestinal epithelium in psoriasis.
Topics: Humans; Methotrexate; Psoriasis | 1966 |
Folic-acid antagonists in psoriasis.
Topics: Aminopterin; Chromosomes; Humans; Leukemia; Lymphocytes; Methotrexate; Middle Aged; Psoriasis | 1966 |
Megaloblastic anaemia during methotrexate treatment of psoriasis.
Topics: Anemia, Macrocytic; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1966 |
The treatment of psoriasis with parenteral methotrexate.
Topics: Adult; Aged; Anemia; Aspartate Aminotransferases; Female; Humans; Infusions, Parenteral; Leukopenia; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nausea; Psoriasis; Schilling Test | 1966 |
[Clinical observations on the treatment of psoriasis with methotrexate. Conclusive notes].
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis | 1966 |
[On the effectiveness of methotrexate in the treatment of psoriasis vulgaris].
Topics: Adolescent; Adult; Aged; Female; Folliculitis; Humans; Injections, Intravenous; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Mucosa; Nausea; Prurigo; Psoriasis; Ulcer | 1966 |
[Internal psoriasis therapy].
Topics: Humans; Methotrexate; Psoriasis; Triamcinolone | 1966 |