Page last updated: 2024-08-25

methotrexate and Pain

methotrexate has been researched along with Pain in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-199015 (12.71)18.7374
1990's23 (19.49)18.2507
2000's31 (26.27)29.6817
2010's31 (26.27)24.3611
2020's18 (15.25)2.80

Authors

AuthorsStudies
Alonso-Castro, AJ; Campos-Xolalpa, N; Hernández-Munive, A; Pérez-González, C; Pérez-Gutiérrez, S; Zapata-Morales, JR1
Buch, MH; Burmester, GR; Bykerk, VP; Fernandez-Nebro, A; Huizinga, T; Kameda, H; Praestgaard, A; Tanaka, Y; van Hoogstraten, H1
Abada, A; Farkas, N; Hegyi, P; Helyes, Z; Juhász, MF; Kiss, F; Nagy, G; Szabó, L; Tóth, L1
Alten, R; Álvaro Gracia, JM; Bello, N; Fleischmann, R; Jia, B; Kaneko, Y; Quebe, A; Taylor, PC; Terres, JR; Walls, C1
Baraliakos, X; Bessette, L; de Vlam, K; Deodhar, A; Feng, D; Gao, T; Kato, K; Lippe, R; Maniccia, A; McInnes, IB; Mease, PJ; Ostor, AJK; Saffore, C; Song, IH; Tillett, W; Zueger, P1
Chatterjee, T; Lindahl, L; Martial, A; Settypalli, S1
Bergman, M; Goldschmidt, D; Martin, N; Patel, J; Song, Y; Suboticki, JL; Tundia, N; Wright, GC1
Hannonen, P; Immonen, J; Sokka, T; Vehmas, J; Weman, L1
Mathieu, S; Sellam, J; Soubrier, M; Tournadre, A1
Fautrel, B; Haladyj, E; Takeuchi, T; van de Laar, MAFJ; Wang, D; Wu, J1
Alenius, GM; Askling, J; di Giuseppe, D; Exarchou, S; Jacobsson, L; Klingberg, E; Lindström, U; Olofsson, T; Wallman, JK1
Antony, B; Cicuttini, FM; Hill, CL; Jones, G; Kasza, J; Keen, HI; O'Sullivan, R; Teichtahl, AJ; Wang, Y; Wluka, AE1
Dong, F; Huo, W; Lei, L; Liao, X; Qin, F; Wei, W; Zeng, W1
Apparailly, F; Cren, M; Jorgensen, C; Louis-Plence, P; Mausset-Bonnefont, AL; Quentin, J; Vicente, R1
Abdo, HM; Elkholy, MS; Elrewiny, EM; Ibrahim, SM1
Cappelli, LC; Demehri, S; Gelber, AC; Ponor, IL; Wright, SM1
De La Torre, I; De Leonardis, F; Emery, P; Fautrel, B; Fleischmann, R; Kadziola, Z; Kannowski, CL; Nicolay, C; Taylor, PC; van de Laar, M; Zhu, B1
De Cock, D; De Groef, A; Joly, J; Moons, P; Pazmino, S; Stouten, V; Van der Elst, K; Verschueren, P; Vriezekolk, J; Westhovens, R1
Behrens, F; Burkhardt, H; Gnann, H; Greger, G; Koehm, M; Schmalzing, M; Schwaneck, EC; Tony, HP1
Bell-Peter, A; Doria, AS; Feldman, BM; Marcuz, JA; Nozawa, T; Stimec, J; Whitney, K1
Bhatia, S; Herrera Hernandez, LP; Kamboj, AK; Rieck, KM1
Darragh, CT; Merkel, EA; Zwerner, JP1
Singh, V; Zhao, CW1
Alfredsson, L; Bengtsson, C; Källberg, H; Klareskog, L; Saevarsdottir, S; Sandberg, ME; Wesley, A1
Hart, LE1
Xian, CJ; Yu, Y; Zhou, FH; Zhou, XF1
Aglipay, MO; Bechard, MA; Duffy, CM; Jurencak, R; Lemieux, JR; Roth, J; Watanabe Duffy, K1
Alponti, RF; Mendes, MT; Silveira, PF; Yamasaki, SC1
Egsmose, EL; Madsen, OR1
Laev, SS; Salakhutdinov, NF1
Botteman, MF; Cifaldi, MA; Stephens, S; van Hout, BA1
Aggarwal, A; Misra, DP1
Allaart, CF; Dirven, L; Gerards, AH; Huizinga, TW; Kerstens, PJ; Lems, WF; Markusse, IM; Ronday, HK; van Groenendael, JH1
Carroll, WL; Devidas, M; Dupuis, LL; Hunger, SP; Kadan-Lottick, NS; Lu, X; Maloney, KW; Mattano, LA; Mitchell, HR; Sung, L; Winick, N1
Alfredsson, L; Altawil, R; Klareskog, L; Lampa, J; Saevarsdottir, S; Wedrén, S1
Huiping, C; Jie, Y; Miao, X; Tianxiang, O; Xiaorong, M; Yan, X; Yingying, H1
Aghazadeh, N; Akbari, Z; Ghodsi, SZ; Hallaji, Z; Lajevardi, V; Shafiei, Z1
D'Amelio, R; Laganà, B; Vinciguerra, M1
Ong, YL; White, S1
Hannonen, P; Hienonen-Kempas, T; Kauppi, M; Korpela, M; Leirisalo-Repo, M; Möttönen, T; Valleala, H1
Baggott, JE; Morgan, SL1
Burmester, GR; Combe, B; Coteur, G; Kavanaugh, A; Keystone, EC; Mease, P; Nikaï, E; Strand, V; van Vollenhoven, R1
Garate, T; Jaén, P; Ma, DL; Vano-Galvan, S1
Falgarone, G; Legré, V; Lioté, F; Lizard, G; Maillefert, JF; Maynadié, M; Morel, J; Ornetti, P; Puéchal, X; Sibilia, J; Solau, E1
Alemdaroğlu, E; Eroğlu, AG; Ertürk, A1
Böttcher, A; Guder, E; Just, T1
Burmester, GR; Coteur, G; Hiepe, F; Khanna, D; Mease, P; Nikaï, E; Schiff, M; Smolen, JS; Strand, V; van Vollenhoven, RF1
Bitman, B; Chen, L; Curtis, JR; Kavanaugh, A; Navarro-Millan, I; Park, GS; Wang, B; Yang, S1
Jeon, H; Kim, C1
Burmester, GR; Devenport, J; Emery, P; John, A; Ogale, S; Strand, V1
Colebatch, AN; Edwards, CJ; Marks, JL; van der Heijde, DM1
Divala, T; Rylance, J1
Guo, C; Huang, W; Liu, D; Shen, L; Tan, A; Zhu, H1
Damato, R; Di Poi, E; Favret, G; Ferraccioli, GF; Gremese, E; Tomietto, P1
Amara, I; Cohen, S; Crawford, B; Felson, D; Koch, G; Pincus, T; Strand, V; Wolfe, F1
Hall, SC; Lozono, S; Suresh, S1
Cella, D; Fuchs, H; Giles, F; Hurd, D; Martin, PJ; Miller, C; Pulliam, J; Sonis, ST; Wingard, JR1
Dolgova, LN; Noskov, SM; Polyakov, DP; Snigireva, AV; Somova, MA1
Hachem, R; Hanna, H; Raad, I1
Andrews, SM; Brown, JR; Garrett, WV; Pickering, D1
Mutoh, S; Ohkubo, Y; Sasakawa, T; Sasakawa, Y1
Ben Arush, MW; Postovsky, S1
Alstergren, P; Bratt, J; Ernestam, S; Kopp, S; Morin, P; Nordahl, S1
Balint, G; Bröll, J; Emery, P; Kishimoto, T; Maini, RN; Pavelka, K; Petersen, J; Raemen, F; Smolen, J; Szechinski, J; Taylor, PC; Thomson, D1
Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H1
Heiberg, MS; Kaufmann, C; Koldingsnes, W; Kvien, TK; Mikkelsen, K; Mowinckel, P; Rødevand, E1
Foehl, JR; Freundlich, B; MacPeek, D; Pedersen, R; Singh, A; van Riel, PL1
Fernández Echevarría, MA; Flórez, AF; Gallardo Agromayor, E; García-Barredo, R; Gorriño Angulo, M; Landeras Alvaro, RM; Martínez-Taboada, VM1
Chandramohan, M; Groves, C; Healy, PJ; Helliwell, PS1
Nascimento, NG; Olivo, RA; Silveira, PF; Teixeira, CF1
DesPrez, JD; Lehman, JA; Shinn, GL1
Anac, S; Cacavio, A; Caparros, B; Nirenberg, A; Rosen, G; Urban, C1
Ebuchi, M; Katada, M; Maruyama, M; Sugano, N; Takamatsu, H1
Eames, P; Jones, AC1
Halla, JT; Hardin, JG1
van 't Hof, M; van de Putte, LB; van der Heijde, DM; van Riel, PL1
Clemmey, P; Culbertson, AL; Lewis, C; Nicassio, PM; Radojevic, V; Weisman, MH1
Adde, MA; Arndt, C; Gootenberg, J; Horak, ID; Magrath, IT; Neely, JE; Nieder, ML; Seibel, NL; Shad, AT; Venzon, DJ; Weintraub, M1
Beezhold, DH; Michaels, RM; Reading, JC; Ward, JR1
Tulandi, T; Yao, M1
Langevitz, P; Livneh, A; Pras, M; Shemer, J; Zemer, D1
Chan, GC; Chan, LC; Chiu, DC; Ha, SY; Lau, YL; Ma, SK1
Blyth, T; Coote, J; Hunter, JA; Land, D; Stirling, A1
Fifield, J; McQuillan, J; Reisine, S; Tennen, H1
Bran, D; Ling, FW; Lipscomb, GH; Puckett, KJ1
Ferguson, WS1
Gran, JT1
Karemaker, JM; Lenders, JW; Timmers, HJ; Wieling, W1
Dziuba, J; Kleinrok, Z; Patyra, H; Sieklucka-Dziuba, M1
Lerndal, T; Svensson, B1
Agameya, AF; Claman, P; Tawfiq, A1
Helders, PJ; Takken, T; Van der Net, J2
Airò, P; Antonioli, CM; Toniati, P; Vianelli, M1
Cooley, DA; Goldman, AL; Harshbarger, JL; Huffstutter, JE; Hughes, GM; Isern, RA; Keenan, GF; Quinn, A; Roth, SH; Schaible, TF; Shergy, WJ; Spencer-Smith, EA; Toder, JS; Warner, D1
Dunn, S; Guilbert, E; Jacot, F; Lugtig, L; Wiebe, E1
Flynn, DE; Ling, FW; Lipscomb, GH; Meyer, NL; Peterson, M1
Ben Maïz, H; Ben Taarit, C; Turki, S1
Gollnick, H; Martens-Lobenhoffer, J; Meyer, FP; Stötzel, B; Tröger, U1
Puff, KH1
Balcar-Boroń, A; Kurylak, A; Nowaczyk-Michalak, A; Pilecki, O; Trybuś, L; Wysocki, M1
Buzdar, AU; Forman, AD; Frye, DK; Holmes, FA; Hortobagyi, GN; Newton, LK; Raber, MN; Theriault, RL; Walters, RS1
Coblyn, JS; Falchuk, KR; Fraser, PA; Holdsworth, DE; Maier, AL; Weinblatt, ME; Weissman, BN1
Kremer, JM; Phelps, CT1
Elhardt, D; Herborn, G; Karger, T; Menninger, H; Rau, R; Schmitt, J1
Kumar, A; Malaviya, AN; Malaviya, R; Sharma, M; Singh, RJ; Singh, YN1
Cyr, M; Goldstein, R; Karsh, J; McKendry, RJ; Morassut, P1
Graves, T; Kampmann, KK; Rogers, SD1
DeBoom, GW; Jensen, JL; Kanas, RJ1
Allegra, C; Chabner, B; Inghirami, G; Klippel, JH; Shiroky, J; Yarboro, C1
Docken, WP; Warfield, CA1
Kremer, JM; Lee, JK1
Setdikov, RA1
Vogt, D1
Gazet, JC; Smith, R1
Melhorn, DK; Newman, AJ; O'Regan, S1
Henderson, ES; Sandler, SG; Tobin, W1
Mengel, CE1

Reviews

15 review(s) available for methotrexate and Pain

ArticleYear
Janus Kinase Inhibitors Improve Disease Activity and Patient-Reported Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of 24,135 Patients.
    International journal of molecular sciences, 2022, Jan-23, Volume: 23, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Databases, Factual; Humans; Janus Kinase Inhibitors; Janus Kinases; Methotrexate; Pain; Pain Management; Patient Reported Outcome Measures; Randomized Controlled Trials as Topic; Treatment Outcome

2022
Effect of disease-modifying anti-rheumatic drugs in osteoarthritis: A meta-analysis.
    Joint bone spine, 2022, Volume: 89, Issue:6

    Topics: Antirheumatic Agents; Humans; Hydroxychloroquine; Inflammation; Interleukin-1; Methotrexate; Osteoarthritis; Pain; Quality of Life

2022
Comparative effectiveness of improvement in pain and physical function for baricitinib versus adalimumab, tocilizumab and tofacitinib monotherapies in rheumatoid arthritis patients who are naïve to treatment with biologic or conventional synthetic disease
    RMD open, 2020, Volume: 6, Issue:1

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Biological Products; Clinical Trials, Phase III as Topic; Disability Evaluation; Humans; Methotrexate; Network Meta-Analysis; Pain; Pain Measurement; Piperidines; Purines; Pyrazoles; Pyrimidines; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome

2020
Anti-arthritic agents: progress and potential.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cartilage; Drugs, Investigational; Glucocorticoids; Humans; Joints; Methotrexate; Osteoarthritis; Pain

2015
Enthesitis-related arthritis.
    Clinical rheumatology, 2015, Volume: 34, Issue:11

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Etanercept; Exercise Therapy; Humans; Infliximab; Male; Methotrexate; Pain; Quality of Life; Sacroiliitis; Ultrasonography, Doppler

2015
Modulation of T-cell co-stimulation in rheumatoid arthritis: clinical experience with abatacept.
    Clinical drug investigation, 2009, Volume: 29, Issue:3

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Rheumatoid; Fatigue; Humans; Immunoconjugates; Methotrexate; Pain; Quality of Life; Radiography; Sleep; Stimulation, Chemical; T-Lymphocytes; Tumor Necrosis Factor-alpha

2009
Safety of nonsteroidal antiinflammatory drugs and/or paracetamol in people receiving methotrexate for inflammatory arthritis: a Cochrane systematic review.
    The Journal of rheumatology. Supplement, 2012, Volume: 90

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Aspirin; Contraindications; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Evidence-Based Medicine; Expert Testimony; Humans; International Cooperation; Methotrexate; Pain; Pain Management; Randomized Controlled Trials as Topic

2012
Current status of surgical and nonsurgical management of ectopic pregnancy.
    Fertility and sterility, 1997, Volume: 67, Issue:3

    Topics: Female; Humans; Laparoscopy; Laparotomy; Methotrexate; Pain; Pregnancy; Pregnancy Outcome; Pregnancy, Ectopic; Salpingostomy

1997
Clinical presentation, hematologic features and treatment outcome of childhood acute lymphoblastic leukemia: a review of 73 cases in Hong Kong.
    Hematological oncology, 1997, Volume: 15, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Disease-Free Survival; Female; Hemorrhage; Hepatomegaly; Hong Kong; Humans; Immunophenotyping; Infant; Karyotyping; Life Tables; Male; Methotrexate; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Splenomegaly; Survival Analysis; Treatment Outcome

1997
Current therapy of polymyalgia rheumatica.
    Scandinavian journal of rheumatology, 1999, Volume: 28, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Humans; Immunosuppressive Agents; Methotrexate; Pain; Polymyalgia Rheumatica; Pregnenediones

1999
Methotrexate for treating juvenile idiopathic arthritis.
    The Cochrane database of systematic reviews, 2001, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular

2001
Methotrexate for treating juvenile idiopathic arthritis.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Adolescent; Arthritis, Juvenile; Clinical Trials as Topic; Humans; Immunosuppressive Agents; Methotrexate; Pain; Quality of Life; Range of Motion, Articular

2001
[Adult Still's disease: study of a series of 11 cases].
    Journal des maladies vasculaires, 2002, Volume: 27, Issue:1

    Topics: Adult; Anemia; Diagnosis, Differential; Exanthema; Female; Ferritins; Fever; Humans; Incidence; Infections; Liver Function Tests; Male; Methotrexate; Neoplasms; Pain; Prednisone; Prevalence; Retrospective Studies; Still's Disease, Adult-Onset

2002
[Polymyositis].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1

    Topics: Antineoplastic Agents; Child; Dermatomyositis; Enzymes; Humans; Immunosuppression Therapy; Methotrexate; Muscle Tonus; Muscular Atrophy; Myositis; Neoplasms; Pain; Paralysis; Prednisone

1976
Rheumatologic causes of pain: rheumatoid arthritis.
    Hospital practice (Office ed.), 1988, Jan-15, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Hip Prosthesis; Humans; Methotrexate; Pain; Steroids

1988

Trials

38 trial(s) available for methotrexate and Pain

ArticleYear
Achieving pain control in early rheumatoid arthritis with baricitinib monotherapy or in combination with methotrexate versus methotrexate monotherapy.
    RMD open, 2022, Volume: 8, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Double-Blind Method; Humans; Methotrexate; Pain; Purines; Pyrazoles; Quality of Life; Sulfonamides; Treatment Outcome

2022
Effect of upadacitinib on reducing pain in patients with active psoriatic arthritis or ankylosing spondylitis: post hoc analysis of three randomised clinical trials.
    RMD open, 2022, Volume: 8, Issue:1

    Topics: Arthritis, Psoriatic; Double-Blind Method; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Pain; Spondylitis, Ankylosing

2022
Patient-reported outcomes of upadacitinib versus abatacept in patients with rheumatoid arthritis and an inadequate response to biologic disease-modifying antirheumatic drugs: 12- and 24-week results of a phase 3 trial.
    Arthritis research & therapy, 2022, 06-24, Volume: 24, Issue:1

    Topics: Abatacept; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Double-Blind Method; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Middle Aged; Pain; Patient Reported Outcome Measures; Quality of Life; Treatment Outcome

2022
Relative Impact of Pain and Disease Activity on Improvements in Fatigue: Results From 2 Baricitinib Phase 3 Clinical Trials.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2023, Apr-01, Volume: 29, Issue:3

    Topics: Adalimumab; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Fatigue; Humans; Methotrexate; Pain; Treatment Outcome

2023
Methotrexate to treat hand osteoarthritis with synovitis (METHODS): an Australian, multisite, parallel-group, double-blind, randomised, placebo-controlled trial.
    Lancet (London, England), 2023, 11-11, Volume: 402, Issue:10414

    Topics: Australia; Double-Blind Method; Female; Humans; Male; Methotrexate; Osteoarthritis; Pain; Synovitis; Treatment Outcome

2023
Efficacy and safety of different Janus kinase inhibitors combined with methotrexate for the treatment of rheumatoid arthritis: a single-center randomized trial.
    Advances in rheumatology (London, England), 2023, 10-16, Volume: 63, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; China; Drug Therapy, Combination; Female; Humans; Janus Kinase Inhibitors; Male; Methotrexate; Middle Aged; Pain; Retrospective Studies

2023
Efficacy of intralesional methotrexate in the treatment of plantar warts.
    Dermatologic therapy, 2020, Volume: 33, Issue:2

    Topics: Humans; Injections, Intralesional; Methotrexate; Pain; Warts

2020
One in five patients with rapidly and persistently controlled early rheumatoid arthritis report poor well-being after 1 year of treatment.
    RMD open, 2020, Volume: 6, Issue:1

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Fatigue; Female; Humans; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Patient Reported Outcome Measures; Quality of Life; Recovery of Function; Severity of Illness Index; Treatment Outcome

2020
Modelling the cost-effectiveness of combination therapy for early, rapidly progressing rheumatoid arthritis by simulating the reversible and irreversible effects of the disease.
    BMJ open, 2015, Jun-09, Volume: 5, Issue:6

    Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cost-Benefit Analysis; Disease Progression; Drug Therapy, Combination; Female; Health Care Costs; Humans; Joints; Logistic Models; Male; Methotrexate; Middle Aged; Models, Biological; Pain; Quality-Adjusted Life Years; Severity of Illness Index

2015
Anxiety, pain, and nausea during the treatment of standard-risk childhood acute lymphoblastic leukemia: A prospective, longitudinal study from the Children's Oncology Group.
    Cancer, 2016, Apr-01, Volume: 122, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anxiety; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Induction Chemotherapy; Longitudinal Studies; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Nausea; Pain; Parents; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Surveys and Questionnaires; Vincristine

2016
Treatment of erosive oral lichen planus with methotrexate.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2016, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Aged; Dermatologic Agents; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Lichen Planus, Oral; Male; Methotrexate; Middle Aged; Pain; Prospective Studies; Treatment Outcome

2016
Rapid and sustained improvements in health-related quality of life, fatigue, and other patient-reported outcomes in rheumatoid arthritis patients treated with certolizumab pegol plus methotrexate over 1 year: results from the RAPID 1 randomized controlled
    Arthritis research & therapy, 2009, Volume: 11, Issue:6

    Topics: Activities of Daily Living; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Certolizumab Pegol; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Humans; Immunoglobulin Fab Fragments; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Polyethylene Glycols; Quality of Life; Recovery of Function; Severity of Illness Index

2009
Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient-reported outcomes from the RAPID 2 trial.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:6

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Certolizumab Pegol; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epidemiologic Methods; Fatigue; Female; Humans; Immunoglobulin Fab Fragments; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Polyethylene Glycols; Quality of Life; Treatment Outcome

2011
Predicting low disease activity and remission using early treatment response to antitumour necrosis factor therapy in patients with rheumatoid arthritis: exploratory analyses from the TEMPO trial.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Decision Trees; Double-Blind Method; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Receptors, Tumor Necrosis Factor; Remission Induction; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2012
Improvements in health-related quality of life after treatment with tocilizumab in patients with rheumatoid arthritis refractory to tumour necrosis factor inhibitors: results from the 24-week randomized controlled RADIATE study.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:10

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Drug Therapy, Combination; Female; Health Status; Humans; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Quality of Life; Treatment Outcome

2012
Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:8

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Female; HLA-DR1 Antigen; Humans; Male; Methotrexate; Middle Aged; Pain; Sulfasalazine

2002
An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in
    Arthritis and rheumatism, 2003, Volume: 48, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; Health Status; Humans; Isoxazoles; Joints; Leflunomide; Methotrexate; Pain; Pain Measurement; Placebos; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2003
Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy.
    Cancer, 2003, Jul-15, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antimicrobial Cationic Peptides; Child; Deglutition Disorders; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Mouth Mucosa; Pain; Pain Measurement; Peptides; Proteins; Severity of Illness Index; Stomatitis; Treatment Outcome

2003
The use of homeopathic preparation Vozraston in the therapy of patients with rheumatoid arthritis.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Humans; Immunosuppressive Agents; Materia Medica; Methotrexate; Pain; Treatment Outcome

2003
Relationship between myalgias/arthralgias occurring in patients receiving quinupristin/dalfopristin and biliary dysfunction.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Aged; Alkaline Phosphatase; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arthralgia; Biliary Tract Diseases; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Immunosuppressive Agents; Liver Function Tests; Male; Methotrexate; Middle Aged; Muscular Diseases; Neoplasms; Pain; Recurrence; Risk Factors; Tacrolimus; Virginiamycin

2004
Reduction of temporomandibular joint pain after treatment with a combination of methotrexate and infliximab is associated with changes in synovial fluid and plasma cytokines in rheumatoid arthritis.
    Cells, tissues, organs, 2005, Volume: 180, Issue:1

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Cytokines; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Pain; Prospective Studies; Synovial Fluid; Temporomandibular Joint Disorders

2005
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Europe; Female; Humans; Male; Methotrexate; Middle Aged; Pain; Patient Selection; Receptors, Interleukin-6; Safety; Treatment Failure; Treatment Outcome

2006
Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.
    Modern rheumatology, 2006, Volume: 16, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Drug Therapy, Combination; Female; Health Status; Humans; Joints; Male; Methotrexate; Middle Aged; Pain; Prednisolone; Prospective Studies; Remission Induction; Severity of Illness Index; Sulfasalazine

2006
Patient-reported health outcomes in a trial of etanercept monotherapy versus combination therapy with etanercept and methotrexate for rheumatoid arthritis: the ADORE trial.
    Annals of the rheumatic diseases, 2008, Volume: 67, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chi-Square Distribution; Combined Modality Therapy; Etanercept; Follow-Up Studies; Humans; Immunoglobulin G; Immunosuppressive Agents; Methotrexate; Pain; Pain Measurement; Patient Satisfaction; Prospective Studies; Quality of Life; Receptors, Tumor Necrosis Factor; Treatment Outcome

2008
Validity of single variables and indices to measure disease activity in rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:3

    Topics: Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; C-Reactive Protein; Disabled Persons; Hemoglobins; Humans; Hydroxychloroquine; Joints; Methotrexate; Pain; Reproducibility of Results; Severity of Illness Index; Sulfasalazine

1993
The role of helplessness in the response to disease modifying drugs in rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:7

    Topics: Adult; Aged; Arthritis, Rheumatoid; Behavior; Cognition; Disability Evaluation; Female; Gold; Helplessness, Learned; Humans; Joints; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Pain; Self Disclosure; Severity of Illness Index; Sulfasalazine; Time Factors

1993
Severe atypical neuropathy associated with administration of hematopoietic colony-stimulating factors and vincristine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Foot Diseases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ifosfamide; Infant; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Pain; Peripheral Nervous System Diseases; Vincristine

1996
Serum phospholipase A2 activity in patients with rheumatoid arthritis before and after treatment with methotrexate, auranofin, or combination of the two.
    The Journal of rheumatology, 1996, Volume: 23, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Auranofin; Double-Blind Method; Drug Combinations; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Pain; Phospholipases A; Phospholipases A2

1996
Injection of the rheumatoid knee: does intra-articular methotrexate or rifampicin add to the benefits of triamcinolone hexacetonide?
    British journal of rheumatology, 1998, Volume: 37, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Intra-Articular; Knee Joint; Male; Methotrexate; Middle Aged; Pain; Rifampin; Severity of Illness Index; Treatment Outcome; Triamcinolone Acetonide

1998
A clinical study of CPH 82 vs methotrexate in early rheumatoid arthritis.
    Rheumatology (Oxford, England), 2000, Volume: 39, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; Double-Blind Method; Female; Glycosides; Humans; Joints; Lignans; Male; Methotrexate; Middle Aged; Pain; Severity of Illness Index; Treatment Outcome

2000
Anti-tumour necrosis factor treatment with infliximab in a case of giant cell arteritis resistant to steroid and immunosuppressive drugs.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antirheumatic Agents; Azathioprine; Drug Resistance; Drug Therapy, Combination; Female; Giant Cell Arteritis; Health Status; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Pain; Pain Measurement; Prednisone; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2002
Open label study to assess infliximab safety and timing of onset of clinical benefit among patients with rheumatoid arthritis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:4

    Topics: Ambulatory Care; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infliximab; Infusions, Intravenous; Joints; Male; Methotrexate; Middle Aged; Outpatients; Pain; Severity of Illness Index; Time Factors; Treatment Outcome

2002
Comparison of abortions induced by methotrexate or mifepristone followed by misoprostol.
    Obstetrics and gynecology, 2002, Volume: 99, Issue:5 Pt 1

    Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Female; Hemorrhage; Humans; Methotrexate; Mifepristone; Misoprostol; Pain; Pregnancy

2002
Phase II trial of taxol, an active drug in the treatment of metastatic breast cancer.
    Journal of the National Cancer Institute, 1991, Dec-18, Volume: 83, Issue:24

    Topics: Adult; Aged; Agranulocytosis; Alkaloids; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Doxorubicin; Drug Evaluation; Female; Heart Diseases; Humans; Methotrexate; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Peripheral Nervous System Diseases; Remission Induction; Soft Tissue Neoplasms; Thrombocytopenia

1991
Long-term prospective study of methotrexate in the treatment of rheumatoid arthritis. 84-month update.
    Arthritis and rheumatism, 1992, Volume: 35, Issue:2

    Topics: Aged; Arthritis, Rheumatoid; Biopsy; Drug Administration Schedule; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Pain; Prednisone; Prospective Studies; Pulmonary Fibrosis; Radiography; Treatment Outcome

1992
A double-blind comparison of parenteral methotrexate and parenteral gold in the treatment of early erosive rheumatoid arthritis: an interim report on 102 patients after 12 months.
    Seminars in arthritis and rheumatism, 1991, Volume: 21, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Arthrography; Blood Sedimentation; Double-Blind Method; Female; Gold Sodium Thiomalate; Humans; Infusions, Parenteral; Joints; Male; Methotrexate; Middle Aged; Pain; Severity of Illness Index

1991
Gold sodium thiomalate compared to low dose methotrexate in the treatment of rheumatoid arthritis--a randomized, double blind 26-week trial.
    The Journal of rheumatology, 1989, Volume: 16, Issue:3

    Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Gold Sodium Thiomalate; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Pain; Random Allocation

1989
A long-term prospective study of the use of methotrexate in rheumatoid arthritis. Update after a mean of fifty-three months.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Central Nervous System Diseases; Clinical Trials as Topic; Gastrointestinal Diseases; HLA Antigens; Humans; Leukopenia; Methotrexate; Middle Aged; Mouth; Pain; Phenotype; Prospective Studies; Time Factors

1988

Other Studies

65 other study(ies) available for methotrexate and Pain

ArticleYear
Synthesis, antinociceptive and anti-inflammatory effects of porphyrins.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Disease Models, Animal; Edema; Erythrocytes; Hemolysis; Indomethacin; Male; Mice; Naproxen; Nociception; Pain; Pain Measurement; Porphyrins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

2015
Sarilumab monotherapy vs sarilumab and methotrexate combination therapy in patients with rheumatoid arthritis.
    Rheumatology (Oxford, England), 2022, 05-30, Volume: 61, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Fatigue; Humans; Methotrexate; Pain; Treatment Outcome

2022
A Rare Case of Combined Choriocarcinoma and Placental Site Trophoblastic Tumor Presenting as Skin Lesion: A Case Report.
    The American journal of case reports, 2022, Jun-18, Volume: 23

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Methotrexate; Pain; Placenta; Pregnancy; Trophoblastic Tumor, Placental Site; Uterine Neoplasms; Vincristine

2022
Real-world data on seropositive rheumatoid arthritis, then and now: ten-year outcomes of 1151 patients diagnosed between 1997 and 2011.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrexate; Pain; Severity of Illness Index; Treatment Outcome

2023
Methotrexate treatment in early psoriatic arthritis in comparison to rheumatoid arthritis: an observational nationwide study.
    RMD open, 2023, Volume: 9, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Humans; Methotrexate; Pain

2023
Arthritis sensory and motor scale: predicting functional deficits from the clinical score in collagen-induced arthritis.
    Arthritis research & therapy, 2019, 12-04, Volume: 21, Issue:1

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Inflammation; Locomotion; Male; Methotrexate; Mice; Pain; Skin Temperature

2019
A Red, Painful, and Swollen Foot Overlying a Bone Erosion.
    The American journal of medicine, 2020, Volume: 133, Issue:11

    Topics: Aged; Antirheumatic Agents; Arthritis, Psoriatic; Bone Marrow; Diagnosis, Differential; Edema; Enthesopathy; Erythema; Finger Joint; HLA-B27 Antigen; Humans; Infliximab; Male; Methotrexate; Osteomyelitis; Pain; Physical Examination; Psoriasis; Synovitis; Toe Joint; Toe Phalanges

2020
Does concomitant methotrexate confer clinical benefits in patients treated with prior biologic therapy? Analysis of data from a noninterventional study of rheumatoid arthritis patients initiating treatment with adalimumab.
    Medicine, 2020, Volume: 99, Issue:19

    Topics: Adalimumab; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; Female; Health Status; Humans; Male; Methotrexate; Pain; Retrospective Studies; Severity of Illness Index

2020
Tibia stress injury and the imaging appearance of stress fracture in juvenile dermatomyositis: six patients' experiences.
    Pediatric rheumatology online journal, 2021, Feb-17, Volume: 19, Issue:1

    Topics: Adolescent; Analgesics; Antirheumatic Agents; Child; Dermatomyositis; Female; Fractures, Bone; Fractures, Stress; Humans; International Cooperation; Magnetic Resonance Imaging; Male; Methotrexate; Pain; Prednisone; Radiography; Rest; Sedentary Behavior; Tibia

2021
Isolated Polyarteritis Nodosa Presenting as Bilateral Testicular Swelling.
    The American journal of medicine, 2018, Volume: 131, Issue:2

    Topics: Cyclophosphamide; Debridement; Edema; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Orchiectomy; Pain; Polyarteritis Nodosa; Prednisone; Testicular Diseases; Testis

2018
Painful, violaceous plaques in a patient with pruritus.
    Clinical and experimental dermatology, 2017, Volume: 42, Issue:8

    Topics: Humans; Kidney Failure, Chronic; Male; Methotrexate; Middle Aged; Necrosis; Pain; Pancytopenia; Pruritus; Skin; Skin Diseases; Thigh

2017
Childhood acute lymphoblastic leukaemia relapse with atypical localised presentation mimicking ankle trauma in a 28-year-old man.
    BMJ case reports, 2019, May-21, Volume: 12, Issue:5

    Topics: Adult; Ankle; Diagnosis, Differential; Humans; Leucovorin; Male; Methotrexate; Neoplasm Recurrence, Local; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed; Vincristine

2019
Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis.
    Annals of the rheumatic diseases, 2014, Volume: 73, Issue:11

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Early Diagnosis; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Obesity; Overweight; Pain; Pain Measurement; Prognosis; Registries; Remission Induction; Severity of Illness Index; Sweden; Treatment Outcome

2014
ACP Journal Club. Methotrexate reduced pain and improved function in symptomatic knee osteoarthritis.
    Annals of internal medicine, 2014, Aug-19, Volume: 161, Issue:4

    Topics: Humans; Methotrexate; Osteoarthritis, Knee; Pain

2014
Methotrexate chemotherapy triggers touch-evoked pain and increased CGRP-positive sensory fibres in the tibial periosteum of young rats.
    Bone, 2015, Volume: 73

    Topics: Animals; Antimetabolites, Antineoplastic; Calcitonin Gene-Related Peptide; Male; Methotrexate; Pain; Periosteum; Rats; Rats, Sprague-Dawley; Tibia; Touch

2015
Procedural pain and patient-reported side effects with weekly injections of subcutaneous methotrexate in children with rheumatic disorders.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Adolescent; Anorexia; Antirheumatic Agents; Child; Child, Preschool; Cohort Studies; Fatigue; Female; Humans; Incidence; Injections, Subcutaneous; Male; Methotrexate; Nausea; Pain; Pain Measurement; Prospective Studies; Retrospective Studies; Rheumatic Diseases; Vomiting

2014
Efficacy of parenteral administration of bee venom in experimental arthritis in the rat: a comparison with methotrexate.
    Toxicon : official journal of the International Society on Toxinology, 2015, Volume: 98

    Topics: Aminopeptidases; Animals; Antirheumatic Agents; Arthritis, Experimental; Bee Venoms; CD13 Antigens; Cyanosis; Dipeptidyl Peptidase 4; Disease Models, Animal; Edema; Hyperalgesia; Inflammation; Leukocytes, Mononuclear; Male; Methotrexate; Pain; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2015
Interplay between patient global assessment, pain, and fatigue and influence of other clinical disease activity measures in patients with active rheumatoid arthritis.
    Clinical rheumatology, 2015, Volume: 34, Issue:7

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Denmark; Fatigue; Female; Humans; Male; Methotrexate; Middle Aged; Pain; Pain Measurement; Prednisolone; Registries; Reproducibility of Results; Rheumatology; Severity of Illness Index; Visual Analog Scale

2015
Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study.
    Arthritis research & therapy, 2015, Aug-31, Volume: 17

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Disease Progression; Follow-Up Studies; Humans; Joints; Methotrexate; Netherlands; Pain; Pain Measurement; Recurrence; Registries; Severity of Illness Index; Surveys and Questionnaires; Time Factors

2015
Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate.
    Arthritis care & research, 2016, Volume: 68, Issue:8

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Male; Methotrexate; Middle Aged; Odds Ratio; Pain; Pain Measurement; Sweden; Treatment Outcome

2016
[Application of embolic sclerotherapy for the treatment of painful venous malformation in limbs].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2015, Volume: 31, Issue:5

    Topics: Ethanol; Extremities; Humans; Methotrexate; Pain; Pain Management; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Sclerotherapy; Statistics, Nonparametric; Vascular Malformations; Veins

2015
Intra-vitreal methotrexate leads to resolution of intraocular chronic lymphocytic leukaemia.
    British journal of haematology, 2010, Volume: 148, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Eye Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Methotrexate; Pain; Treatment Outcome; Vision Disorders

2010
Rituximab therapy in patients with rheumatoid arthritis refractory or with contraindication to anti-tumour necrosis factor drugs: real-life experience in Finnish patients.
    Scandinavian journal of rheumatology, 2009, Volume: 38, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Chi-Square Distribution; Contraindications; Drug Therapy, Combination; Female; Finland; Humans; Male; Medical Records; Methotrexate; Middle Aged; Pain; Pain Measurement; Prednisolone; Retrospective Studies; Rituximab; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2009
Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:8

    Topics: Aldehyde Oxidase; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Folic Acid; Health Status; Humans; Joints; Leucovorin; Methotrexate; Pain; Tandem Mass Spectrometry; Treatment Outcome

2009
Painful nail lesions.
    Australian family physician, 2010, Volume: 39, Issue:3

    Topics: Clobetasol; Dermatologic Agents; Glucocorticoids; Humans; Male; Methotrexate; Middle Aged; Nail Diseases; Onycholysis; Pain; Psoriasis; PUVA Therapy

2010
Prediction of response to disease modifying antirheumatic drugs in rheumatoid arthritis.
    Joint bone spine, 2010, Volume: 77, Issue:6

    Topics: Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; Biomarkers; Female; Humans; Joints; Leukocytes, Mononuclear; Logistic Models; Male; Methotrexate; Middle Aged; Multidrug Resistance-Associated Proteins; Pain; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; ROC Curve; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha

2010
A sarcoidosis patient with hand involvement and large pulmonary lymph nodes: results of 1-year treatment with methotrexate.
    Clinical rheumatology, 2013, Volume: 32 Suppl 1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Finger Phalanges; Humans; Immunosuppressive Agents; Indomethacin; Lung; Lymph Nodes; Lymphatic Diseases; Methotrexate; Pain; Radiography, Thoracic; Sarcoidosis; Treatment Outcome

2013
[Unilateral odynophagia in rheumatoid arthritis].
    Laryngo- rhino- otologie, 2011, Volume: 90, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cooperative Behavior; Deglutition Disorders; Diagnosis, Differential; Diclofenac; Drug Therapy, Combination; Dysphonia; Endoscopy; Female; Folic Acid; Humans; Interdisciplinary Communication; Lymphopenia; Methotrexate; Middle Aged; Misoprostol; Opportunistic Infections; Oral Ulcer; Pain; Pharyngitis; Prednisolone

2011
Letter: Methotrexate for localized morphea with severe pain: a case report.
    Dermatology online journal, 2011, Dec-15, Volume: 17, Issue:12

    Topics: Dermatologic Agents; Female; Humans; Methotrexate; Pain; Scleroderma, Localized; Severity of Illness Index; Treatment Outcome; Young Adult

2011
Case report--progressive immobilising back and joint pain.
    Malawi medical journal : the journal of Medical Association of Malawi, 2011, Volume: 23, Issue:2

    Topics: Adult; Ankle Joint; Anti-Inflammatory Agents; Antirheumatic Agents; Back Pain; Hip Joint; Humans; Knee Joint; Male; Methotrexate; Pain; Prednisolone; Radiography; Spine; Spondylitis, Ankylosing; Treatment Outcome

2011
Bilateral uterine artery chemoembolization with methotrexate for cesarean scar pregnancy.
    American journal of obstetrics and gynecology, 2012, Volume: 207, Issue:5

    Topics: Abortifacient Agents, Nonsteroidal; Adult; Chemoembolization, Therapeutic; Chorionic Gonadotropin, beta Subunit, Human; Cicatrix; Female; Fever; Humans; Hysterectomy; Length of Stay; Methotrexate; Pain; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Ultrasonography; Uterine Artery Embolization; Uterine Hemorrhage; Vaginal Birth after Cesarean; Young Adult

2012
Large-dose intravenous methotrexate-induced cutaneous toxicity: can oral magnesium oxide reduce pain?
    Anesthesia and analgesia, 2003, Volume: 96, Issue:5

    Topics: Abdominal Neoplasms; Adolescent; Analgesics, Opioid; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Drug Eruptions; Female; Fentanyl; Humans; Magnesium Oxide; Methotrexate; Pain; Pain Measurement

2003
Critical limb ischaemia associated with chemotherapy for breast cancer.
    Journal of the Royal Society of Medicine, 2004, Volume: 97, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fingers; Fluorouracil; Foot; Humans; Ischemia; Methotrexate; Middle Aged; Pain

2004
FK506 ameliorates spontaneous locomotor activity in collagen-induced arthritis: implication of distinct effect from suppression of inflammation.
    International immunopharmacology, 2005, Volume: 5, Issue:3

    Topics: Animals; Arthritis, Experimental; Body Weight; Female; Femur Head; Hyperalgesia; Immunosuppressive Agents; Inflammation; Methotrexate; Motor Activity; Muscle, Skeletal; Pain; Proteoglycans; Rats; Rats, Inbred Lew; Tacrolimus

2005
Acral erythema caused by high-dose methotrexate therapy in patients with osteogenic sarcoma.
    Pediatric hematology and oncology, 2005, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Erythema; Female; Foot; Hand; Humans; Methotrexate; Osteosarcoma; Pain

2005
The comparative effectiveness of anti-TNF therapy and methotrexate in patients with psoriatic arthritis: 6 month results from a longitudinal, observational, multicentre study.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:8

    Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Psoriatic; Chi-Square Distribution; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Joints; Logistic Models; Male; Methotrexate; Middle Aged; Norway; Pain; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor-alpha

2007
Radiological aid to clinical diagnosis of Schnitzler's syndrome: multimodality imaging approach.
    Clinical rheumatology, 2008, Volume: 27, Issue:1

    Topics: Adult; Antirheumatic Agents; Diagnostic Imaging; Drug Therapy, Combination; Humans; Ilium; Immunosuppressive Agents; Interleukin 1 Receptor Antagonist Protein; Magnetic Resonance Imaging; Male; Methotrexate; Pain; Schnitzler Syndrome; Sclerosis; Tomography, X-Ray Computed; Treatment Outcome; Urticaria

2008
MRI changes in psoriatic dactylitis--extent of pathology, relationship to tenderness and correlation with clinical indices.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:1

    Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Edema; Female; Finger Joint; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Methotrexate; Pain; Severity of Illness Index; Synovitis; Toe Joint; Treatment Outcome

2008
Methotrexate and cyclosporine treatments modify the activities of dipeptidyl peptidase IV and prolyl oligopeptidase in murine macrophages.
    Clinical & developmental immunology, 2008, Volume: 2008

    Topics: Animals; Cyclosporine; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Therapy, Combination; Enzyme Inhibitors; Immunosuppressive Agents; Inflammation; Macrophages, Peritoneal; Male; Methotrexate; Mice; Pain; Prolyl Oligopeptidases; Serine Endopeptidases

2008
Chemotherapy for the control of pain in inoperable cancer. A report of intra-arterial infusion in four patients.
    The Ohio State medical journal, 1967, Volume: 63, Issue:8

    Topics: Aged; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Methotrexate; Middle Aged; Neoplasms; Pain

1967
Chemical pleuritis as the cause of acute chest pain following high-dose methotrexate treatment.
    Cancer, 1983, Jan-01, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Child; Diagnosis, Differential; Female; Humans; Leukemia; Male; Methotrexate; Pain; Pleurisy; Pneumothorax; Radiography; Thorax

1983
[Complications in the intraperitoneal chemotherapy with the implantable intraperitoneal port and the strategy for the prevention of the complication].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:11

    Topics: Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Fluorouracil; Gastrointestinal Neoplasms; Humans; Infusion Pumps, Implantable; Infusions, Parenteral; Intestinal Perforation; Male; Methotrexate; Middle Aged; Pain

1995
Acute diffuse muscular pain following initiation of methotrexate therapy.
    Annals of the rheumatic diseases, 1994, Volume: 53, Issue:7

    Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Methotrexate; Middle Aged; Muscular Diseases; Pain

1994
Underrecognized postdosing reactions to methotrexate in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1994, Volume: 21, Issue:7

    Topics: Administration, Oral; Arthralgia; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Muscular Diseases; Pain; Time Factors

1994
Seronegative spondyloarthropathy in familial Mediterranean fever.
    Seminars in arthritis and rheumatism, 1997, Volume: 27, Issue:2

    Topics: Achilles Tendon; Adrenal Cortex Hormones; Adult; Ankle; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Back Pain; Colchicine; Familial Mediterranean Fever; Female; Heel; HLA-B27 Antigen; Humans; Joint Diseases; Knee; Male; Methotrexate; Middle Aged; Neck Pain; Pain; Prevalence; Sacroiliac Joint; Shoulder; Spinal Diseases; Sulfasalazine

1997
Depression and the long-term risk of pain, fatigue, and disability in patients with rheumatoid arthritis.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:10

    Topics: Arthritis, Rheumatoid; Depression; Disability Evaluation; Fatigue; Humans; Methotrexate; Pain; Prednisone; Risk Factors; Severity of Illness Index; Time Factors

1998
Management of separation pain after single-dose methotrexate therapy for ectopic pregnancy.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adult; Female; Humans; Methotrexate; Pain; Pain Management; Pregnancy; Pregnancy, Ectopic; Retrospective Studies

1999
From twisted ankles.
    Medicine and health, Rhode Island, 1999, Volume: 82, Issue:6

    Topics: Ankle Injuries; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Casts, Surgical; Child; Follow-Up Studies; Fractures, Bone; Humans; Male; Mercaptopurine; Methotrexate; Pain; Prednisone; Remission Induction; Vincristine; Wrist Injuries

1999
Baroreflex failure following radiation therapy for nasopharyngeal carcinoma.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1999, Volume: 9, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Baroreflex; Blood Pressure; Combined Modality Therapy; Cyclophosphamide; Fatigue; Head and Neck Neoplasms; Heart Rate; Humans; Hypotension, Orthostatic; Lymphatic Metastasis; Male; Methotrexate; Nasopharyngeal Neoplasms; Pain; Posture; Radiotherapy; Remission Induction; Valsalva Maneuver; Vincristine

1999
Central action of some cytostatics--methotrexate (MTX) and doxorubicin (DXR). I. Long-term influence on the pain sensitivity and activity of brain dopaminergic system in mice.
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1998, Volume: 53

    Topics: Analgesics; Animals; Behavior, Animal; Body Weight; Brain; Catalepsy; Doxorubicin; Drug Interactions; Exploratory Behavior; Female; Haloperidol; Locomotion; Male; Methotrexate; Mice; Norepinephrine; Pain

1998
Predictors of treatment failure for ectopic pregnancy treated with single-dose methotrexate.
    Fertility and sterility, 2000, Volume: 74, Issue:5

    Topics: Abortifacient Agents, Nonsteroidal; Adult; Chorionic Gonadotropin, beta Subunit, Human; Cohort Studies; Contraindications; Female; Humans; Methotrexate; Pain; Pregnancy; Pregnancy, Ectopic; Prognosis; Retrospective Studies; Treatment Failure; Uterine Hemorrhage

2000
Oral methotrexate for treatment of ectopic pregnancy.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:6

    Topics: Abortifacient Agents, Nonsteroidal; Administration, Oral; Adult; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Methotrexate; Pain; Pregnancy; Pregnancy, Ectopic; Retreatment; Treatment Outcome; Ultrasonography

2002
Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate.
    BMJ (Clinical research ed.), 2002, Jun-22, Volume: 324, Issue:7352

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Benzimidazoles; Dermatologic Agents; Drug Interactions; Humans; Lymphoma, T-Cell, Cutaneous; Male; Methotrexate; Middle Aged; Muscular Diseases; Omeprazole; Pain; Pantoprazole; Sulfoxides

2002
[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:11-12

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Erythema; Female; Hand Dermatoses; Humans; Infusions, Intravenous; Male; Methotrexate; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1992
Long-term prospective study of the use of methotrexate in the treatment of rheumatoid arthritis. Update after a mean of 90 months.
    Arthritis and rheumatism, 1992, Volume: 35, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Cohort Studies; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Pain; Prospective Studies; Pulmonary Fibrosis; Radiography; Treatment Outcome

1992
Effects of methotrexate on clinical and immunological parameters in refractory rheumatoid arthritis: a prospective study.
    British journal of rheumatology, 1991, Volume: 30, Issue:1

    Topics: Arthritis, Rheumatoid; Humans; Immunoglobulins; Methotrexate; Pain; Prospective Studies; Severity of Illness Index

1991
Acral erythema secondary to high-dose cytosine arabinoside with pain worsened by cyclosporine infusions.
    Cancer, 1989, Jun-15, Volume: 63, Issue:12

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Cyclosporins; Cytarabine; Erythema; Female; Foot Dermatoses; Graft vs Host Disease; Hand Dermatoses; Humans; Infusions, Intravenous; Male; Methotrexate; Pain; Pharmaceutical Vehicles; Whole-Body Irradiation

1989
Painful oral mucosal ulcers in a patient with small cell carcinoma of the lung.
    Journal of the American Dental Association (1939), 1987, Volume: 115, Issue:1

    Topics: Aged; Carcinoma, Small Cell; Gingivitis, Necrotizing Ulcerative; Humans; Lung Neoplasms; Male; Methotrexate; Mouth Mucosa; Pain

1987
High dose intravenous methotrexate with leucovorin rescue in rheumatoid arthritis.
    The Journal of rheumatology, 1988, Volume: 15, Issue:2

    Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; HLA-DR Antigens; Humans; Injections, Intravenous; Leucovorin; Methotrexate; Pain; Pilot Projects; Recurrence; T-Lymphocytes

1988
[Clinical picture and treatment of lesions of the epidural space in lymphosarcoma].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Epidural Space; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Pain; Prednisolone; Spinal Neoplasms; Vincristine

1986
[New viewpoints concerning leukemia in children. Treatment of complications].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:1

    Topics: Acute Disease; Anemia, Aplastic; Antineoplastic Agents; Child; gamma-Globulins; Humans; Infections; Leukemia; Methotrexate; Pain

1970
Intra-arterial chemotherapy for patients with inoperable carcinoma of the pancreas.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:11

    Topics: Catheterization; Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Jaundice; Methods; Methotrexate; Pain; Pancreatic Neoplasms; Vincristine

1974
Methotrexate-induced bone pain in childhood leukemia.
    American journal of diseases of children (1960), 1973, Volume: 126, Issue:4

    Topics: Bone Diseases; Bone Regeneration; Child; Child, Preschool; Female; Fractures, Bone; Humans; Leukemia, Lymphoid; Male; Methotrexate; Osteoporosis; Pain; Radiography; Remission, Spontaneous; Time Factors

1973
Vincristine-induced neuropathy. A clinical study of fifty leukemic patients.
    Neurology, 1969, Volume: 19, Issue:4

    Topics: Achilles Tendon; Action Potentials; Adult; Child; Child, Preschool; Cranial Nerves; Drug Synergism; Electrodiagnosis; Gait; Gastrointestinal Diseases; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Motor Neurons; Nervous System Diseases; Neural Conduction; Pain; Paralysis; Prednisolone; Reflex, Abnormal; Sensation; Time Factors; Vincristine

1969
Abdominal crisis in the malignant carcinoid syndrome.
    Archives of internal medicine, 1966, Volume: 117, Issue:2

    Topics: Abdomen; Adult; Humans; Male; Malignant Carcinoid Syndrome; Methocarbamol; Methotrexate; Pain

1966