Page last updated: 2024-08-25

methotrexate and Osteoarthritis, Knee

methotrexate has been researched along with Osteoarthritis, Knee in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's8 (80.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Cicuttini, F; Ding, C; Gu, J; Han, W; Huang, C; Hunter, D; Leng, X; Li, T; Li, Z; Mei, Y; Wang, K; Xu, J; Yu, Q; Zeng, X; Zhang, Z; Zhao, Y; Zhu, Z1
Oberhofer, E1
Hart, LE1
Hämäläinen, M; Moilanen, E; Moilanen, T; Tuure, L1
Arden, NK; Batley, M; Birrell, F; Cocks, K; Conaghan, PG; Doherty, M; Edwards, CJ; Garrood, T; Grainger, AJ; Green, M; Hewitt, C; Hughes, R; Kingsbury, SR; Moots, R; O'Neill, TW; Roddy, E; Scott, DL; Tharmanathan, P; Torgerson, DJ; Watt, FE1
Higuchi, Y; Kitamura, H; Morikawa, T; Murao, N; Saitoh, R; Sato, H; Tamura, T1
Nikitin, AV; Starodubtseva, IA; Vasilieva, LV1
Asanuma, K; Emura, T; Higuchi, Y; Homma, A; Ikemi, M; Ikeya, H; Ishizawa, T; Izutani, N; Kanda, M; Kato, T; Kitagawa, H; Kitamura, H; Maeda, K; Matsuura, T; Morikawa, T; Nohmi, K; Okamachi, A; Sato, H; Sato, S; Suzuki, R; Takahashi, K; Tamura, T; Watanabe, T; Yamazaki, T1
Chinoy, H; Foulkes, AC; Griffiths, CE; Warren, RB1
Ash, ZR; Caperon, AR; Conaghan, PG; Grainger, AJ; Hensor, EM; Wenham, CY1

Trials

3 trial(s) available for methotrexate and Osteoarthritis, Knee

ArticleYear
Can low-dose methotrexate reduce effusion-synovitis and symptoms in patients with mid- to late-stage knee osteoarthritis? Study protocol for a randomised, double-blind, and placebo-controlled trial.
    Trials, 2020, Sep-16, Volume: 21, Issue:1

    Topics: Aged; Double-Blind Method; Humans; Knee Joint; Methotrexate; Multicenter Studies as Topic; Osteoarthritis, Knee; Quality of Life; Randomized Controlled Trials as Topic; Synovitis; Treatment Outcome

2020
Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial.
    Trials, 2015, Mar-04, Volume: 16

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents; Arthralgia; Clinical Protocols; Double-Blind Method; Humans; Intention to Treat Analysis; Linear Models; Logistic Models; Magnetic Resonance Imaging; Methotrexate; Multivariate Analysis; Osteoarthritis, Knee; Pain Measurement; Research Design; Synovitis; Time Factors; Treatment Outcome; United Kingdom

2015
Methotrexate for pain relief in knee osteoarthritis: an open-label study.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:5

    Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Prospective Studies; Radiography; Severity of Illness Index; Synovitis; Treatment Outcome; United Kingdom

2013

Other Studies

7 other study(ies) available for methotrexate and Osteoarthritis, Knee

ArticleYear
[Weight loss as the alpha and omega. New EULAR recommendations for hip and knee arthrosis].
    MMW Fortschritte der Medizin, 2013, Aug-22, Volume: 155, Issue:14

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Combined Modality Therapy; Exercise; Feeding Behavior; Humans; Methotrexate; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Education as Topic; Shoes; Weight Loss

2013
ACP Journal Club. Methotrexate reduced pain and improved function in symptomatic knee osteoarthritis.
    Annals of internal medicine, 2014, Aug-19, Volume: 161, Issue:4

    Topics: Humans; Methotrexate; Osteoarthritis, Knee; Pain

2014
Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes.
    Scandinavian journal of rheumatology, 2015, Volume: 44, Issue:1

    Topics: Antirheumatic Agents; Chondrocytes; Dexamethasone; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Glucocorticoids; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Intramolecular Oxidoreductases; Methotrexate; Osteoarthritis, Knee; Primary Cell Culture; Prostaglandin-E Synthases; Real-Time Polymerase Chain Reaction; Sulfasalazine

2015
Novel hyaluronic acid-methotrexate conjugate suppresses joint inflammation in the rat knee: efficacy and safety evaluation in two rat arthritis models.
    Arthritis research & therapy, 2016, Apr-01, Volume: 18

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cell Proliferation; Drug Carriers; Female; Fibroblasts; Humans; Hyaluronic Acid; Injections, Intra-Articular; Male; Methotrexate; Osteoarthritis, Knee; Rabbits; Rats

2016
[The Analysis of Efficacy of The Application of Interleukin-1 Inhibitor in the Complex Therapy of Secondary Osteoarthritis Taking Into Account the Dynamics of Clinical and Functional Indicators].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2016, Issue:2

    Topics: Adult; Anthraquinones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Combined Modality Therapy; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Interleukin-1; Laser Therapy; Male; Methotrexate; Middle Aged; Osteoarthritis, Knee; Patient Acuity; Quality of Life; Recovery of Function; Treatment Outcome

2016
Novel hyaluronic acid-methotrexate conjugates for osteoarthritis treatment.
    Bioorganic & medicinal chemistry, 2009, Jul-01, Volume: 17, Issue:13

    Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Fibroblasts; Humans; Hyaluronic Acid; Injections, Intra-Articular; Knee; Male; Methotrexate; Osteoarthritis; Osteoarthritis, Knee; Rats; Rats, Inbred Lew; Synovial Fluid; Tumor Necrosis Factor-alpha

2009
Unmasking of axial spondyloarthritis and oligoarthritis following discontinuation of tumour necrosis factor inhibitor therapy for psoriasis.
    The Journal of dermatological treatment, 2014, Volume: 25, Issue:1

    Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Cyclosporine; Drug Substitution; Humans; Immunosuppressive Agents; Knee Injuries; Male; Methotrexate; Osteoarthritis, Knee; Psoriasis; Spondylarthritis; Tumor Necrosis Factor-alpha; Ustekinumab; Withholding Treatment

2014