Page last updated: 2024-08-25

methotrexate and Oral Ulcer

methotrexate has been researched along with Oral Ulcer in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (7.50)	18.2507
2000's	6 (15.00)	29.6817
2010's	25 (62.50)	24.3611
2020's	6 (15.00)	2.80

Authors

Authors	Studies
Guo, H; Hu, K; Liu, W; Tan, Z; Zhao, R	1
Fischer, EA; Hetland, ML; Krabbe, S	1
Adnan, IA; Biswas, J; Kharelo, SR	1
Honda, N; Kawano, H; Kubo, M; Matsuura, T; Nawata, T; Shiragami, K; Yano, M	1
Ali, S; Magdy, E	1
Michaels, PD; Ramia de Cap, M	1
Biju, IK; Manappallil, RG; Peringat, J; Prasan, D	1
Blanco-Carrión, A; Chamorro-Petronacci, C; Gándara-Vila, P; García-García, A; Gómez-García, FJ; Lorenzo-Pouso, AI; Padín-Iruegas, ME; Pérez-Sayáns, M	1
Lalani, R; Lyu, H; Solomon, DH; Vanni, K	1
Ahmed, EM; Ali, S; Fayed, HL; Gaafar, SM; Rashed, LM	1
Duan, W; Kang, HL; Yang, SL; Zhao, Q	1
Dong, J; Du, L; Jin, Y; Li, G; Wang, L; Xu, Q	1
Berndt, R; Gassling, V; Kriegelstein, S; Troeltzsch, M; von Blohn, G; Woodlock, T	1
Hanakawa, H; Nishizaki, K; Orita, Y; Sato, Y; Uno, K; Yoshino, T	1
Kessler, HP; Naidu, A; Pavelka, MA	1
Johnson, RJ; Owen, RG; Sadasivam, N	1
Abbass, K; Gertner, E; Haveman, L	1
Benchekroun, S; Lamchahab, M	1
Horie, N; Kaneko, T; Kawano, R; Shimoyama, T	1
Català, A; Puig, L; Roé, E; Vilarrasa, E; Yélamos, O	1
Foerster, J; Ogston, S; West, J	1
Doležalová, P; Fingerhutová, Š; Fráňová, J; Hoza, J; Kobrová, K; Linková, L; Němcová, D; Saifridová, M; Srp, R; Uher, M	1
Fujii, K; Higashi, Y; Kanekura, T; Kawai, K; Kusuyama, J; Shima, K; Tanimoto, A; Yoshimitsu, M; Yoshioka, T	1
Aldridge, T; Brennan, PA; Ilankovan, V	1
Brown, A; Cowan, DA; Warner, J; Whitmore, SE	1
Bautista, P; García-Del Moral, R; Kilmurray, LG; López-Chumillas, A; O'Valle, F; Pastor-Nieto, MA; Puig, AM	1
Costello, DJ; Papaliodis, GN; Stone, JH	1
Kim, P; Reeves, D; Roufas, A; Sutton, G	1
Doran, RM; Jackson, TE; Pathak, S	1
Böttcher, A; Guder, E; Just, T	1
Hashizume, H; Kawamura, T; Suda, T; Takigawa, M; Tokura, Y; Uchiyama, I	1
Attard, AA; Dunn, PJ; James, GJ; Praveen, P	1
Arranz, R; Cannata-Ortiz, J; García-Noblejas, A; Velasco, A	1
Greenwood, M; Meechan, JG	1
Collingwood, J; Deeming, GM; Pemberton, MN	1
Falconer, DT; Kalantzis, A; Marshman, Z; Morgan, PR; Odell, EW	1
Goksugur, N; Yilmaz, F	1
Hamuryudan, V; Ince, A; Yazici, H; Yazici, Y	1
Hamai, K; Imai, H; Komatsuda, A; Miura, AB; Mizuki, N; Motegi, M; Ohtani, H	1
Bauer, J; Fartasch, M; Schell, H; Schuler, G	1

Reviews

8 review(s) available for methotrexate and Oral Ulcer

Article	Year
Management options for low-dose methotrexate-induced oral ulcers: A systematic review. Medicina oral, patologia oral y cirugia bucal, 2019, Mar-01, Volume: 24, Issue:2 Topics: Administration, Oral; Databases, Factual; Humans; Methotrexate; Oral Ulcer; Treatment Outcome	2019
Low-Dose Methotrexate and Mucocutaneous Adverse Events: Results of a Systematic Literature Review and Meta-Analysis of Randomized Controlled Trials. Arthritis care & research, 2020, Volume: 72, Issue:8 Topics: Adult; Aged; Alopecia; Antirheumatic Agents; Double-Blind Method; Female; Folic Acid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Randomized Controlled Trials as Topic; Rheumatic Diseases; Stomatitis	2020
Epstein-Barr virus-positive oral ulceration simulating Hodgkin lymphoma in a patient treated with methotrexate: case report and review of the literature. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014, Volume: 72, Issue:4 Topics: Aged, 80 and over; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Epstein-Barr Virus Infections; Female; Follow-Up Studies; Gingival Diseases; Hodgkin Disease; Humans; Immunosuppressive Agents; Methotrexate; Oral Ulcer; Prednisone	2014
Safety and Efficacy of Methotrexate in Psoriasis: A Meta-Analysis of Published Trials. PloS one, 2016, Volume: 11, Issue:5 Topics: Arthritis, Rheumatoid; Dermatologic Agents; Humans; Immunosuppressive Agents; Methotrexate; Nausea; Opportunistic Infections; Oral Ulcer; Patient Safety; Psoriasis; Risk; Treatment Outcome	2016
Epstein-Barr-virus-related mucocutaneous ulceration that mimics oral squamous cell carcinoma: the importance of recognising this new condition. The British journal of oral & maxillofacial surgery, 2017, Volume: 55, Issue:4 Topics: Aged, 80 and over; Antirheumatic Agents; Biopsy; Carcinoma, Squamous Cell; Diagnosis, Differential; Disease Progression; Epstein-Barr Virus Infections; Humans; Immunohistochemistry; Male; Methotrexate; Mouth Neoplasms; Oral Ulcer; Prednisolone; Radiography, Panoramic	2017
[Methotrexate-associated lymphoproliferative disorder presenting as oral ulcers in a patient with rheumatoid arthritis]. Actas dermo-sifiliograficas, 2009, Volume: 100, Issue:2 Topics: Aged; Antigens, CD; Antigens, Neoplasm; Arthritis, Rheumatoid; Biomarkers, Tumor; Epstein-Barr Virus Infections; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunoglobulin kappa-Chains; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Oral Ulcer; Remission Induction	2009
Oral effects of low-dose methotrexate treatment. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2005, Volume: 100, Issue:1 Topics: Aged; Antirheumatic Agents; Bone Marrow; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Female; Folic Acid Antagonists; Gastrointestinal Tract; Humans; Liver; Male; Methotrexate; Middle Aged; Mouth Mucosa; Oral Ulcer; Retrospective Studies; Stomatitis	2005
Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome): a case report and literature review. The American journal of the medical sciences, 1997, Volume: 314, Issue:5 Topics: Adult; Behcet Syndrome; Drug Therapy, Combination; Female; Genital Diseases, Female; Genotype; HLA Antigens; Humans; Japan; Methotrexate; Oral Ulcer; Pentoxifylline; Polychondritis, Relapsing; Polymorphism, Restriction Fragment Length; Syndrome; Ulcer	1997

Trials

1 trial(s) available for methotrexate and Oral Ulcer

Article	Year
The frequency and clinical characteristics of methotrexate (MTX) oral toxicity in rheumatoid arthritis (RA): a masked and controlled study. Clinical rheumatology, 1996, Volume: 15, Issue:5 Topics: Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Single-Blind Method; Stomatitis; Time Factors	1996

Other Studies

31 other study(ies) available for methotrexate and Oral Ulcer

Article	Year
Severe toxic effects of low-dose methotrexate treatment for placenta accreta in a patient with methylenetetrahydrofolate reductase mutations. Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1 Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oral Ulcer; Placenta Accreta; Pregnancy; Severity of Illness Index; Stomatitis	2020
Folinic acid alleviates side effects of methotrexate in arthritis patients with side effects despite folic acid supplementation: an observational cohort study. Rheumatology (Oxford, England), 2020, Nov-01, Volume: 59, Issue:11 Topics: Aged; Antirheumatic Agents; Arthritis; Arthritis, Psoriatic; Chemical and Drug Induced Liver Injury; Cohort Studies; Drug Substitution; Female; Folic Acid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Oral Ulcer; Retrospective Studies; Rheumatic Fever; Treatment Failure; Vitamin B Complex	2020
Biological agent in prevention of ocular recurrence in Behçets disease: a case report. Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH, 2019, Volume: 11, Issue:22 Topics: Adalimumab; Administration, Oral; Adult; Anti-Inflammatory Agents; Behcet Syndrome; Drug Combinations; Genital Diseases, Male; Humans; Immunosuppressive Agents; Male; Methotrexate; Oral Ulcer; Recurrence; Ulcer; Uveitis, Anterior	2019
Oral ulcers with amyloidosis secondary to rheumatoid arthritis. Rheumatology (Oxford, England), 2021, Jun-18, Volume: 60, Issue:6 Topics: Aged; Amyloidosis; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Methotrexate; Oral Ulcer; Prednisolone	2021
Stratification of methotrexate-induced oral ulcers in rheumatoid arthritis patients. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 2021, Volume: 41, Issue:3 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrexate; Oral Ulcer; Treatment Outcome	2021
High prevalence of methotrexate use in patients with Epstein-Barr virus-positive mucocutaneous ulcer may cause confounding bias. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2021, Volume: 34, Issue:11 Topics: Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Humans; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Oral Ulcer; Prevalence; Receptors, Interleukin-2	2021
Severe bone marrow suppression due to methotrexate toxicity following aceclofenac-induced acute kidney injury. BMJ case reports, 2018, Jun-05, Volume: 2018 Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow Cells; Bone Marrow Diseases; Diclofenac; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Methotrexate; Oral Ulcer	2018
Evaluation of topical human platelet lysate versus topical clobetasol in management of methotrexate-induced oral ulceration in rheumatoid arthritis patients: Randomized-controlled clinical trial. International immunopharmacology, 2019, Volume: 73 Topics: Administration, Topical; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Platelets; Clobetasol; Glucocorticoids; Humans; Methotrexate; Middle Aged; Oral Ulcer	2019
Efficacy of Combination Therapy with Actinomycin D and Methotrexate in the Treatment of Low-Risk Gestational Trophoblastic Neoplasia. Chemotherapy, 2019, Volume: 64, Issue:1 Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, Combination; Female; Gestational Trophoblastic Disease; Hematologic Diseases; Humans; Logistic Models; Methotrexate; Middle Aged; Neoplasm Staging; Oral Ulcer; Pregnancy; Prognosis; Treatment Outcome; Young Adult	2019
Riboflavin laurate nanosuspensions as an intramuscular injection for long-term riboflavin supplementation. International journal of pharmaceutics, 2013, Jun-25, Volume: 450, Issue:1-2 Topics: Animals; Dietary Supplements; Injections, Intramuscular; Laurates; Male; Methotrexate; Nanostructures; Oral Ulcer; Rats; Rats, Sprague-Dawley; Riboflavin; Riboflavin Deficiency; Suspensions; Vitamin B Complex	2013
Oral mucositis in patients receiving low-dose methotrexate therapy for rheumatoid arthritis: report of 2 cases and literature review. Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 115, Issue:5 Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Overdose; Female; Folic Acid; Follow-Up Studies; Gingivitis, Necrotizing Ulcerative; Hospitalization; Humans; Lip Diseases; Methotrexate; Oral Ulcer; Skin Ulcer; Stomatitis; Stomatitis, Herpetic; Tongue Diseases	2013
Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders. Acta medica Okayama, 2013, Volume: 67, Issue:4 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Lymphoproliferative Disorders; Male; Methotrexate; Oral Ulcer; Oropharynx	2013
Resolution of methotrexate-induced Epstein-Barr virus-associated mucocutaneous ulcer. British journal of haematology, 2014, Volume: 165, Issue:5 Topics: Aged; Epstein-Barr Virus Infections; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoproliferative Disorders; Male; Methotrexate; Oral Ulcer	2014
Esophagitis dissecans superficialis due to severe methotrexate toxicity. Endoscopy, 2014, Volume: 46 Suppl 1 UCTN Topics: Arthritis; Esophagitis; Esophagoscopy; Female; Folic Acid Deficiency; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Oral Ulcer; Skin Ulcer	2014
[Methotrexate toxicity during acute leukemia lymphoblastic]. The Pan African medical journal, 2014, Volume: 17 Topics: Antimetabolites, Antineoplastic; Cheilitis; Female; Humans; Methotrexate; Oral Ulcer; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult	2014
Methotrexate-related lymphoproliferative disorder arising in the gingiva of a patient with rheumatoid arthritis. Australian dental journal, 2015, Volume: 60, Issue:3 Topics: Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Gingival Neoplasms; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Oral Ulcer; Osteonecrosis	2015
Acute severe methotrexate toxicity in patients with psoriasis: a case series and discussion. Dermatology (Basel, Switzerland), 2014, Volume: 229, Issue:4 Topics: Acute Disease; Aged, 80 and over; Atrial Fibrillation; Deglutition Disorders; Drug Eruptions; Dyslipidemias; Fever; Humans; Hypertension; Immunosuppressive Agents; Male; Medication Errors; Methotrexate; Middle Aged; Oral Ulcer; Pancytopenia; Psoriasis; Renal Insufficiency, Chronic; Shock, Septic	2014
Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration. Pediatric rheumatology online journal, 2016, Jun-14, Volume: 14, Issue:1 Topics: Abdominal Pain; Administration, Oral; Anemia; Antirheumatic Agents; Arthritis, Juvenile; Arthritis, Psoriatic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Kaplan-Meier Estimate; Male; Methotrexate; Nausea; Oral Ulcer; Prospective Studies; Treatment Outcome; Vomiting	2016
Lymphomatoid granulomatosis initially presenting as ulcerated subcutaneous and muscle lesions without pulmonary involvement. The Journal of dermatology, 2017, Volume: 44, Issue:5 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Lymphomatoid Granulomatosis; Male; Methotrexate; Oral Ulcer	2017
Mucocutaneous ulcerations secondary to methotrexate. Cutis, 2008, Volume: 81, Issue:5 Topics: Administration, Oral; Adult; Drug Interactions; Female; Folic Acid Antagonists; Humans; Methotrexate; Mouth Mucosa; Oral Ulcer; Psoriasis; Skin; Skin Ulcer	2008
A 29-year-old woman with headache, fever, right leg numbness, and dysphagia. Arthritis care & research, 2010, Volume: 62, Issue:2 Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Behcet Syndrome; Deglutition Disorders; Diagnosis, Differential; Drug Therapy, Combination; Female; Fever; Headache; Humans; Hypesthesia; Infliximab; Leg; Magnetic Resonance Imaging; Methotrexate; Oral Ulcer	2010
A rare unilateral case of ocular mucous membrane pemphigoid. Cornea, 2010, Volume: 29, Issue:12 Topics: Biopsy; Complement C3; Conjunctivitis; Drug Therapy, Combination; Epistaxis; Eyelid Diseases; Fluorescent Antibody Technique, Indirect; Granuloma; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Oral Ulcer; Pemphigoid, Benign Mucous Membrane; Prednisone	2010
Behçet disease presenting with frosted branch angiitis. Ocular immunology and inflammation, 2011, Volume: 19, Issue:1 Topics: Arthritis; Azathioprine; Behcet Syndrome; Fundus Oculi; Hematocele; HLA-B Antigens; HLA-B51 Antigen; Humans; Male; Methotrexate; Middle Aged; Oral Ulcer; Papilledema; Prednisolone; Retinal Hemorrhage; Retinal Vasculitis; Treatment Outcome; Visual Acuity; Vitrectomy	2011
[Unilateral odynophagia in rheumatoid arthritis]. Laryngo- rhino- otologie, 2011, Volume: 90, Issue:8 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cooperative Behavior; Deglutition Disorders; Diagnosis, Differential; Diclofenac; Drug Therapy, Combination; Dysphonia; Endoscopy; Female; Folic Acid; Humans; Interdisciplinary Communication; Lymphopenia; Methotrexate; Middle Aged; Misoprostol; Opportunistic Infections; Oral Ulcer; Pain; Pharyngitis; Prednisolone	2011
Epstein-Barr virus-positive mucocutaneous ulcers as a manifestation of methotrexate-associated B-cell lymphoproliferative disorders. Acta dermato-venereologica, 2012, Volume: 92, Issue:3 Topics: Antiviral Agents; Epstein-Barr Virus Infections; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Oral Ulcer; Polymyositis	2012
Epstein-Barr virus-positive mucocutaneous ulcer of the oral cavity: the importance of having a detailed clinical history to reach a correct diagnosis. Oral surgery, oral medicine, oral pathology and oral radiology, 2012, Volume: 114, Issue:2 Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Breast Neoplasms; Diagnosis, Differential; DNA, Viral; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Medical History Taking; Methotrexate; Oral Ulcer	2012
[Spontaneous regression of immunodeficiency associated plasmablastic lymphoma related to methotrexate after decrease of dosage]. Medicina clinica, 2013, Jun-18, Volume: 140, Issue:12 Topics: Aged; Arthritis, Psoriatic; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunoglobulin Light Chains; Immunophenotyping; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Immunoblastic; Methotrexate; Neoplasm Proteins; Oral Ulcer; Remission, Spontaneous	2013
General medicine and surgery for dental practitioners. Part 8: Musculoskeletal system. British dental journal, 2003, Sep-13, Volume: 195, Issue:5 Topics: Anesthesia, Dental; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Dental Care for Chronically Ill; Drug Interactions; Gingival Overgrowth; Humans; Lichen Planus, Oral; Methotrexate; Musculoskeletal Diseases; Oral Ulcer	2003
Methotrexate and oral ulceration. British dental journal, 2005, Jan-22, Volume: 198, Issue:2 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Methotrexate; Middle Aged; Oral Ulcer	2005
Medical image. Extensive oral ulcerations. The New Zealand medical journal, 2006, Sep-22, Volume: 119, Issue:1242 Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Female; Hematologic Tests; Humans; Methotrexate; Oral Ulcer; Treatment Outcome	2006
[Ulcerative stomatitis as clinical clue to inadvertent methotrexate overdose]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:9 Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Medication Errors; Methotrexate; Mouth Mucosa; Oral Ulcer; Stomatitis	1999