methotrexate has been researched along with Neoplasms, Nervous System in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (73.33) | 18.7374 |
| 1990's | 4 (13.33) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Borowitz, MJ; Burke, MJ; Carroll, AJ; Carroll, WL; Dai, Y; Devidas, M; Gore, L; Hardy, KK; Heerema, NA; Hilden, JM; Hunger, SP; Kairalla, JA; Larsen, E; Loh, ML; Rabin, KR; Raetz, EA; Salzer, WL; Winick, N; Wood, B; Zweidler-McKay, PA | 1 |
| Kong, J; Li, J; Wan, J; Wu, X; Xiao, J; Xu, H; Yang, B; Yu, L | 1 |
| Behin, A; Choquet, S; Drouet, T; Guillevin, R; Hoang Xuan, K; Psimaras, D | 1 |
| Baehring, JM; Hochberg, FH; Kleopa, KA; Stern, BV | 1 |
| Boivin, P; Courouble, Y; Elghozi, D; Gislon, J; Schuller, E; Solal-Celigny, P | 1 |
| Capizzi, RL; Carney, C; Delaney, D; Kahn, L; Kirsch, M; Lipper, S; Neijstrom, ES; Rudnick, SA | 1 |
| Arizaga, R; Castaño, J; Chamoles, N; Fisman, N; Leiguarda, R; Moreno, R; Pavlovsky, S | 1 |
| Gaedicke, G; Haas, RJ; Janka, G; Kohne, E; Netzel, B | 1 |
| Chervinsky, DS; Creaven, PJ; Ettinger, LJ; Freeman, AI | 1 |
| Donaldson, M; Hammond, GD; Littman, P; Nesbit, ME; Ortega, JA; Robison, LL; Sather, H | 1 |
| Habs, M; Lin, PZ; Schmähl, D | 1 |
| Bessho, F; Hayashi, Y; Kamoshita, S; Kinumaki, H; Kobayashi, M; Yokota, S | 1 |
| Athens, JW; Balcerzak, SP; Coltman, CA; Costanzi, JJ; Dabich, L; Gumbart, C; Head, DR; Kopecky, KJ; Morrison, FS; Saiki, JH | 1 |
| Chan, WC; Krendel, DA; Stahl, RL | 1 |
| Budman, DR; Cuttner, J; Davey, F; Henderson, ES; Lee, EJ; Mayer, RJ; Mick, R; Paciucci, PA; Sobol, R; Weiss, RB | 1 |
| Petrov, SA | 1 |
| Steinherz, PG | 1 |
| Fujimoto, T; Koizumi, S; Mimaya, J; Ninomiya, T; Takeda, T; Utsumi, J; Yanai, M; Yatabe, M | 1 |
| Fairclough, D; Mulhern, RK; Ochs, J; Wasserman, AL | 1 |
| Maiakova, SA; Makhonova, LA | 1 |
| Boyett, JM; Brecher, ML; Freeman, AI; Glicksman, A; Holland, JF; Jones, B; Sinks, LF; Weinberg, V | 1 |
| Russo, A; Schiliro', G | 1 |
| Cabanillas, F; Perez-Soler, R; Smith, TL | 1 |
| Biggar, R; Neequaye, JE; Nkrumah, FK | 1 |
| Armitage, JO; Aunan, SB; Burns, CP; Dick, FR; Edwards, RW; Gingrich, RD; Leimert, JT; Maguire, LC | 1 |
| Aur, RJ; Berg, R; Hustu, HO; Ochs, JJ; Rivera, G; Simone, JV | 1 |
| Berry, DH; Boyett, JM; Castleberry, RP; Culbert, S; Glicksman, AS; Humphrey, GB; Land, VJ; Thomas, PR; Vats, T | 1 |
| Baer, MR; Flexner, JM; Stein, RS | 1 |
| George, SL; Mauer, AM; Ochs, JJ; Simone, JV | 1 |
| Bleyer, WA; Poplack, DG | 1 |
2 review(s) available for methotrexate and Neoplasms, Nervous System
| Article | Year |
|---|---|
Radiotherapy vs intrathecal chemotherapy for CNS prophylaxis in childhood ALL.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Combined Modality Therapy; Humans; Injections, Spinal; Methotrexate; Nervous System Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Prophylaxis and treatment of leukemia in the central nervous system and other sanctuaries.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Clinical Trials as Topic; Combined Modality Therapy; Humans; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Leucovorin; Leukemia; Male; Methotrexate; Nervous System Neoplasms; Prognosis; Radiation Injuries; Testicular Neoplasms | 1985 |
11 trial(s) available for methotrexate and Neoplasms, Nervous System
| Article | Year |
|---|---|
Impact of Intrathecal Triple Therapy Versus Intrathecal Methotrexate on Disease-Free Survival for High-Risk B-Lymphoblastic Leukemia: Children's Oncology Group Study AALL1131.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Dexamethasone; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Nervous System Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 2020 |
Sanctuary therapy: a randomized trial of 724 children with previously untreated acute lymphoblastic leukemia: A Report from Children's Cancer Study Group.
Topics: Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukocyte Count; Male; Methotrexate; Nervous System Neoplasms; Prognosis; Radiotherapy Dosage; Random Allocation; Testicular Neoplasms | 1982 |
Late intensification with POMP chemotherapy prolongs survival in acute myelogenous leukemia--results of a Southwest Oncology Group study of rubidazone versus adriamycin for remission induction, prophylactic intrathecal therapy, late intensification, and l
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Combined Modality Therapy; Daunorubicin; Doxorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Levamisole; Mercaptopurine; Methotrexate; Nervous System Neoplasms; Prednisone; Survival Analysis; Vincristine | 1992 |
Phase III trial of brief intensive treatment of adult acute lymphocytic leukemia comparing daunorubicin and mitoxantrone: a CALGB Study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Methotrexate; Middle Aged; Mitoxantrone; Nervous System Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
Comparison of intermittent or continuous methotrexate plus 6-mercaptopurine in regimens for standard-risk acute lymphoblastic leukemia in childhood (JCCLSG-S811). The Japanese Children's Cancer and Leukemia Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Nervous System Neoplasms; Prednisone; Random Allocation; Remission Induction; Time Factors; Vincristine; Vindesine | 1988 |
Memory function in disease-free survivors of childhood acute lymphocytic leukemia given CNS prophylaxis with or without 1,800 cGy cranial irradiation.
Topics: Child; Humans; Leukemia, Lymphoid; Memory Disorders; Methotrexate; Nervous System Neoplasms; Neuropsychological Tests; Radiotherapy | 1988 |
Intermediate dose methotrexate in childhood acute lymphoblastic leukemia resulting in decreased incidence of testicular relapse.
Topics: Actuarial Analysis; Acute Disease; Child; Child, Preschool; Clinical Trials as Topic; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Methotrexate; Nervous System Neoplasms; Random Allocation; Risk; Testicular Neoplasms | 1986 |
The enigma of testicular leukemia: a critical review.
Topics: Animals; Bone Marrow Diseases; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Prognosis; Rats; Research Design; Sex Factors; Testicular Neoplasms | 1986 |
Comparison of maintenance treatment regimens for first central nervous system relapse in children with acute lymphocytic leukemia. A Pediatric Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Radiotherapy Dosage; Time Factors | 1985 |
The importance of an isolated central nervous system relapse in children with acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Clinical Trials as Topic; Humans; Leukemia, Lymphoid; Methotrexate; Nervous System Neoplasms; Prognosis; Radiotherapy Dosage | 1985 |
Prophylaxis and treatment of leukemia in the central nervous system and other sanctuaries.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Clinical Trials as Topic; Combined Modality Therapy; Humans; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Leucovorin; Leukemia; Male; Methotrexate; Nervous System Neoplasms; Prognosis; Radiation Injuries; Testicular Neoplasms | 1985 |
18 other study(ies) available for methotrexate and Neoplasms, Nervous System
| Article | Year |
|---|---|
[Efficacy and Security of Intrathecal with Methotrexate in the Treatment of Meningeal Carcinomatosis].
Topics: Adult; Aged; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Neoplasm Metastasis; Nervous System Neoplasms; Retrospective Studies; Treatment Outcome | 2016 |
[Bing-Neel syndrome revealing Waldenström's macroglobulinemia].
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone and Bones; Central Nervous System Diseases; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Magnetic Resonance Imaging; Male; Meningitis; Methotrexate; Middle Aged; Neoplasm Invasiveness; Nervous System Neoplasms; Polyradiculopathy; Prednisone; Rituximab; Spinal Nerve Roots; Syndrome; Vincristine; Waldenstrom Macroglobulinemia | 2010 |
Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Demyelinating Diseases; Female; Head and Neck Neoplasms; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Motor Neuron Disease; Neoplasm Recurrence, Local; Nervous System Neoplasms; Neural Conduction; Peripheral Nervous System Diseases; Scalp; Skin Neoplasms; Thiotepa; Vincristine | 2006 |
[Cerebromeningeal location of chronic lymphoid leukemia. Rapid immunochemical diagnosis and complete remission by intrathecal chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Cyclophosphamide; Humans; Immunochemistry; Immunoglobulins; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Nervous System Neoplasms; Time Factors; Vincristine | 1983 |
High-dose methotrexate in small cell lung cancer. Lack of efficacy in preventing CNS relapse.
Topics: Aged; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nervous System Neoplasms; Paraneoplastic Syndromes; Smoking; Thrombocytopenia | 1983 |
Neuropsychological study in patients with ALL. Two different CNS prevention therapies--cranial irradiation plus IT methotrexate vs. IT methotrexate alone.
Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Intelligence Tests; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms; Psychomotor Performance; Skull; Tomography, X-Ray Computed | 1983 |
Therapy of acute lymphocytic leukemia in childhood with intermediate dose methotrexate and CNS irradiation. A report of the ALL 77-02 study group.
Topics: Acute Disease; Antigens, Surface; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Risk | 1983 |
Pharmacokinetics of methotrexate following intravenous and intraventricular administration in acute lymphocytic leukemia and non-Hodgkin's lymphoma.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Half-Life; Humans; Infant; Injections, Intravenous; Injections, Intraventricular; Kinetics; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms | 1982 |
Carcinogenic activity in rats of combined treatment with cyclophosphamide, methotrexate and 5-fluorouracil.
Topics: Adrenal Gland Neoplasms; Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukemia, Experimental; Male; Mammary Neoplasms, Experimental; Methotrexate; Neoplasms, Experimental; Nervous System Neoplasms; Rats; Urinary Bladder Neoplasms | 1981 |
Liver function studies in children with acute lymphocytic leukemia after cessation of therapy.
Topics: Adolescent; Adult; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Child; Daunorubicin; Follow-Up Studies; Humans; Liver; Mercaptopurine; Methotrexate; Nervous System Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1994 |
Lymphomatous polyneuropathy. Biopsy of clinically involved nerve and successful treatment.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Cytarabine; Electrophysiology; Female; Humans; Leg; Leucovorin; Lymphoma; Methotrexate; Nervous System; Nervous System Neoplasms; Vincristine | 1991 |
[Neuroleukemia in mice with leukemia L1210 treated with methotrexate].
Topics: Animals; Drug Evaluation, Preclinical; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Nervous System Neoplasms | 1989 |
[Consolidating chemotherapy in the treatment program of acute lymphoblastic leukemia in children].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Leucovorin; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Prednisolone; Prognosis; Time Factors; Vincristine | 1986 |
Central nervous system prophylaxis with combined intravenous and intrathecal methotrexate in diffuse lymphoma of aggressive histologic type.
Topics: Adult; Age Factors; Bone Marrow; Humans; Injections, Intravenous; Injections, Spinal; L-Lactate Dehydrogenase; Lymphoma; Methotrexate; Models, Biological; Nervous System Neoplasms; Risk | 1986 |
Intrathecal chemoprophylaxis in the prevention of central nervous system relapse in Burkitt's lymphoma.
Topics: Abdominal Neoplasms; Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Ghana; Head and Neck Neoplasms; Humans; Injections, Spinal; Methotrexate; Neoplasm Staging; Nervous System Neoplasms; Retrospective Studies | 1985 |
Long-term relapse-free survival in adult acute lymphoblastic leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Combined Modality Therapy; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Nervous System Neoplasms; Prednisone; Prognosis; Recurrence; Vincristine | 1985 |
Central nervous system morbidity following an initial isolated central nervous system relapse and its subsequent therapy in childhood acute lymphoblastic leukemia.
Topics: Acute Disease; Central Nervous System Diseases; Child; Combined Modality Therapy; Humans; Intelligence Tests; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Radiography; Recurrence | 1985 |
Improved survival in adult acute lymphoblastic leukemia. Need for more effective CNS prophylaxis.
Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Diseases; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Male; Methotrexate; Nervous System Neoplasms; Prednisone; Time Factors; Vincristine | 1985 |