Page last updated: 2024-08-25

methotrexate and Necrosis

methotrexate has been researched along with Necrosis in 155 studies

Research

Studies (155)

Timeframe	Studies, this research(%)	All Research%
pre-1990	55 (35.48)	18.7374
1990's	41 (26.45)	18.2507
2000's	26 (16.77)	29.6817
2010's	23 (14.84)	24.3611
2020's	10 (6.45)	2.80

Authors

Authors	Studies
Guan, H; Harrold, LR; Karis, E; Middaugh, N; Solomon, DH; Stryker, S; Yoshida, K	1
Lefor, AK; Miyato, H; Omameuda, T; Sata, N	1
Aelion, J; Amital, H; Arikan, D; Buttgereit, F; Chen, S; D'Cunha, R; Kupper, H; Pang, Y; Radstake, T; Rojkovich, B; Yang, Y; Zubrzycka-Sienkiewicz, A	1
Balayla, J; Cohen, A; Gil, Y; Levin, I; Zubkov, A	1
Herceg-Čavrak, V; Hojsak, I; Jadrešin, O; Kolaček, S; Mišak, Z; Pivac, VT	1
Fujiwara, T; Jeys, LM; Parry, MC; Stevenson, JD; Sumathi, V; Tsoi, K; Tsuda, Y	1
Aguado, L; Gutiérrez, M; Idoate, MÁ; Moreno-Artero, E; Querol-Cisneros, E; Rodríguez-Garijo, N; Tomás-Velázquez, A	1
Abdel-Wahab, BA; Ali, FEM; Alkahtani, SA; Alshabi, AM; Hassanein, EHM; Mahnashi, MH	1
Audino, AN; Chung, C; Fernandez Faith, E; Guinipero, T; Ravi, M; Ridpath, A	1
Abo-Haded, HM; Al-Ahmadi, O; Al-Johani, Z; El-Agamy, DS; Elkablawy, MA	1
Chen, CB; Chen, TJ; Chung, WH; Huang, YH; Hui, RC; Hung, SI; Lu, YT; Wang, CW; Wang, KH; Yang, LC	1
de Lima, AD; Guido, MC; Kalil-Filho, R; Maranhão, RC; Marques, AF; Nicolau, JC; Salemi, VM; Tavares de Melo, MD; Tavares, ER	1
Darragh, CT; Merkel, EA; Zwerner, JP	1
El-Sayed, YS; Khafaga, AF	1
Rojanapanthu, P; Srisuttiyakorn, C	1
Cumpston, KL; Lenczowski, J; Schall, C; Wills, BK	1
Goto, H; Mashima, A; Muramatsu, D; Umazume, K; Usui, Y	1
Escherich, G; Hagel, C; Hartz, B; Löbel, U	1
Ciobanu, E; Hinschberger, O; Jaeger-Bizet, F; Kieffer, P; Lannes, B; Lohmann, C; Martzolff, L; Vo, BD	1
Akiba, D; Idei, M; Nakano, Y; Nishizawa, S; Saito, T; Soejima, Y; Takahashi, M; Yamamoto, J	1
Luo, DQ	1
Chen, KE; Sung, JM; Yang, CC; Yu-Yun Lee, J	1
Amici, A; Andreani, C; Bartolacci, C; Belletti, B; Gambini, V; Garulli, C; Giangrossi, M; Iezzi, M; Kalogris, C; Lucci, C; Marchini, C; Pietrella, L; Pucciarelli, S; Tilio, M; Zabaleta, ME	1
Koyama, T; Shintaku, M; Teraoka, S; Toyooka, N; Tsudo, M	1
Aslaner, A; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Gül, S; Öğünç, AV; Oruç, MT; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ	1
Cei, M; Dentali, F; Mumoli, N; Vitale, J	1
Alratrout, J; Alshammasi, F; Ansari, N	1
Burcu, B; Kanter, M; Karabacak, R; Orhon, ZN; Yarali, O	1
Ariga, T; Iwafuchi, H; Kobayashi, I; Kuwana, M; Takezaki, S; Tozawa, Y; Ueki, M; Watanabe, S; Yamada, M	1
Bramsiepe, I; Danz, B; Fiedler, E; Heine, R; Holzhausen, HJ; Marsch, WC; Taube, KM	1
Lazaridou, E; Patsatsi, A; Sotiriadis, D; Sotiriou, E; Tsorova, C	1
Castiglione-Gertsch, M; Coates, AS; Colleoni, M; Gelber, RD; Goldhirsch, A; Maiorano, E; Mastropasqua, MG; Price, KN; Regan, MM; Viale, G	1
Frew, R; Nelson, PP; Sawyer, TW; Tenn, C; Vair, C; Wang, Y; Weiss, MT; Yin, J	1
Sharaf, PH; Yazici, Y	1
Chalmers, RJ; Helbling, I; Yates, VM	1
Ambrosio, MR; Di Mari, N; Luzzi, L; Monciatti, I; Onorati, M; Rocca, BJ; Spina, D; Tosi, P	1
Álvarez-Argüelles, H; Brito, ML; González-Brito, G; Hernández-Nieto, L; Lakhwani, S; Raya, JM	1
Diven, DG; Fridlington, JL; Hall, CS; Reichenberg, JS; Tripple, JW	1
Chang, SK; Hahn, JS; Kim, GE; Kim, YB; Koom, WS; Lee, KK; Park, W; Shim, SJ; Suh, CO; Yang, WI	1
BELLMAN, S; HUGOSSON, R; JOHANSSON, B; SJOEGREN, SE	1
BLENDIS, LM; SHRANK, AB	1
Arayssi, TK; Mroué, KH; Rbeiz, JG; Sharara, NH	1
Gorlick, R; Healey, J; Huvos, AG; Kellick, M; Lo, S; Meyers, PA; Sankaran, M; Shi, W; Wexler, LH; Zelcer, S	1
Antonescu, CR; Berens, ME; Brown, KM; Chen, W; Daluski, A; Gorlick, R; Healey, JH; Henry, MM; Hilmer, SC; Huvos, AG; Lafleur, B; Macdonald, TJ; Mazza, B; McDonough, WS; Meyers, PA; Mintz, MB; Ramsey, KE; Sowers, R; Stephan, DA	1
Hoeger, PH; Tsianakas, A	1
Aizman, RI; Capitanio, A; Celsi, G; Chen, M; Grönroos, M; Jahnukainen, T	1
Gardner, J; Jardine, DL; Steele, R	1
Chalmers, L; Chamberlain, M; Robb, J; Rojiani, A	1
Auvin, S; Carré, D; Chabrier, PE; Marin, JG; Pignol, B	1
Ando, K; Ishikura, R; Kamikonya, N; Kaneda, Y; Nagami, Y; Nakao, N; Ogawa, M; Pande, AR; Tanizawa, T	1
Abe, Y; Imataki, O; Kawakami, K; Kusafuka, K; Tamai, Y	1
Rüdt, R; Sanchez, E; Shirahama, J; Wittig, Ch	1
Athyros, VG; Chrysomallis, F; Karagiannis, A; Pyrpasopoulou, A; Zamboulis, C	1
Pfeiffer, J; Ridder, GJ	1
Choi, G; Hong, W; Kim, YC; Shin, J; Song, H	1
Flechtenmacher, C; Longerich, T; Schirmacher, P	1
Callejas-Rubio, JL; Guerrero Fernández, M; Ortego-Centeno, N; Ríos Fernández, R; Serrano Falcón, MM	1
Hatakeyama, S; Okeda, R; Suzuki, K; Takemura, T	1
Allen, JC; Horten, BC; Shapiro, WR	1
Ojeda, VJ	1
Grisold, W; Lutz, D; Wolf, D	1
Ishida, Y; Morimatsu, M; Nakazato, Y	1
Bleyer, WA	1
Bachmann, KD; Gröbe, H; Menne, R; Müller, KM	1
Avella, M; Bacci, G; Casadei, R; Cazzola, A; Ferrari, S; Lari, S; Monti, C; Picci, P; Prever, BA; Ruggieri, P	1
Andou, Y; Asano, K; Fujii, H; Haga, Y; Kajita, M; Katayama, I; Matsumoto, Y; Mori, O; Ohashi, M; Tsuge, I	1
DiFrancesco, L; Greenwald, RA; Miller, F	1
Higaki, S; Takeyama, S; Tateishi, A; Yamanashi, M	1
Arndt, CA; Edmonson, JH; Gilchrist, GS; Miser, JS; Pritchard, DJ; Rock, MG; Schaid, DJ; Shives, TC; Smithson, WA	1
Fink-Puches, R; Kerl, H; Soyer, HP	1
Donovan, JP; Markin, RS; Shaw, BW; Zetterman, RK	1
Kumazaki, T; Nakazawa, S; Node, Y; Shimura, T; Takahashi, H; Tamai, J	1
Algra, PR; de Waal, R; Heimans, JJ; Scheltens, P; Wolbers, JG	1
Kim, TH; Packer, RJ; Priest, JR; Rorke, LB; Simonton, SC; Spiegel, RH; Watterson, J	1
Bailey, LL; Bouchart, F; Fukushima, N; Gundry, SR; Matsumiya, G; Zuppan, C	1
Marcove, RC	1
Hirschel, B; Jeanprêtre, M; Pechère, M; Saurat, JH; Vogel, JJ; Zulian, GB	1
Calzolari, A; Cerinic, MM; Ermini, M; Falcini, F; Franchi, A; Taccetti, G; Trapani, S	1
Antezana, C; Brahm, J; Cumsille, MA; González-Koch, A; Smok, G	1
Arima, K; Iwasaka, T; Kato, A; Matsunaga, H; Nomiyama, M; Sugimori, H	1
Obwegeser, A; Seiwald, M; Stockhammer, G	1
Bach, N; Schaffner, F; Thung, SN	1
Casper, E; Gorlick, R; Healey, JH; Heller, G; Huvos, AG; Lane, J; Meyers, PA	1
Chambers, JT; Cracchiolo, B; Kohorn, EI; Odunsi, KO; Parkash, V; Peck, LL; Taylor, KJ	1
Enneking, WF; Lindner, NJ; Scarborough, MT; Spanier, SS	1
Drag-Zalesińska, M; Gebarowska, E; Wysocka, T; Zabel, M	1
Blay, JY; Brunat-Mentigny, M; Chauvin, F; Demaille, MC; Gentet, JC; Iliescu, C; Krakowski, I; Pacquement, H; Philip, T; Soler-Michel, P; Thiesse, P	1
Bargalló, N; Berenguer, J; Buñesch, L; Burrel, M; Cofan, F; Mercader, JM	1
Elonen, E; Juvonen, E; Parkkali, T; Ruutu, T; Volin, L	1
Clarke, J; Hettiaratchy, S; Moloney, D	1
Antunes, NL; Lis, E; Rosenblum, M; Souweidane, MM; Steinherz, PG; Wolden, S	1
Zimmerman, HJ	2
Begeer, JH; Ebels, EJ; Mehta, DM; Piers, DA; Postma, A	1
Gutjahr, P; Kretzschmar, K; Kutzner, J; Voth, D	1
Conway, JJ; Liu, HM; Maurer, HS; Vongsvivut, S	1
Grøn, P; Kolzet, DJ; Krakow, AA; Shklar, G	1
Huvos, AG; Marcove, RC; Rosen, G	1
Allen, RM; Bloomer, JR; Klatskin, G; Kobayashi, K	1
Di Chiro, G; Pratt, RA; Weed, JC	1
Franke, HD; Lierse, W	1
Bjorgen, JE; Gold, LH	1
Custer, RP; Freeman-Narrod, M; Narrod, SA	1
Aye, MS; Fayos, JV; Kim, YH	1
Nyfors, A; Poulsen, H	1
Cerný, K; Krajcí, A; Uvízi, J	1
Herman, MM; Long, TF; Rubinstein, JL; Wilbur, JR	1
Bogliolo, G; Celle, G; Dodero, M; Fresco, G; Mansi, C; Pannaccuilli, I; Savarino, V	1
Phillips, FS; Sternberg, SS	1
Bellamy, N; Dewar, CL	1
Belshe, BD; Gumerlock, MK; Madsen, R; Watts, C	1
Gütling, E; Kleihues, P; Landis, T	1
Fairclough, DL; Fletcher, BD; Hanna, SL; Le, AH; Meyer, WH; Parham, DM	1
Merchant, RE; Watts, RG	1
Arechaga, S; Bellas, C; Berenguer, A; Calleja, JL; García Villanueva, A; Marcos Robles, J; Montalbán, C; Patier, JL	1
Ferrari, AM; Marsden, FW; McCarthy, SW; Stephens, FO	1
Bacchini, P; Bacci, G; Bertoni, F; Capanna, R; Dallari, D; Picci, P; Pignatti, G	1
Artigas, J; Cervos-Navarro, J; Cruz-Sanchez, FF; Ferszt, R; Rossi, ML	1
Cserhati, MD; Exner, GU; Groscurth, P; Honegger, HP; von Hochstetter, A	1
Feldmann, G; Gébauer, C; Guyard, B; Madelenat, P; Ménard, A; Michaud, P; Perrotez, C	1
Ahern, MJ; Hall, PD; Jenner, MA	1
Intragumtornchai, T; Kasantikul, V; Phanthumchinda, K	1
Borisov, VI; Frank, GA; Volchenko, NN	1
Regli, L; Teta, D; Uldry, PA	1
Bader, J; Danforth, DN; Egan, E; Lampert, M; Lippman, ME; McDonald, H; Steinberg, SM; Swain, SM	1
Brick, JE; Chang, WL; Kujala, GA; Shamma'a, JM	1
Baum, LG; Feig, SA; Villareal, B; Vinters, HV	1
Dawson, P; Dean, L; Nachman, J; Shermeta, D; Simon, MA; Vogelzang, NJ	1
Akutsu, Y; Kuzuhara, M; Matsumoto, M; Nakazawa, S; Shimura, T; Yoshida, D	1
Crossley, J; Harman, RR; Jones, SK; Reynolds, NJ	1
Voigtmann, R	1
Okeda, R; Shibutani, M	1
Graham, RM; Macfarlane, AW; Ng, HW; Verbov, JL	1
Elemenoglou, J; Kosmidis, PA; Kottaridis, S; Uzunoglou, N	1
Arends, JW; Blijham, GH; Braat, SH; de Haan, J; Hoogland, HJ; van Krimpen, C	1
Eady, RA; Logan, RA; McFadden, JP	1
Bleyer, WA; Geraci, JP; Geyer, JR; Hubbard, BA; Milstein, JM; Shaw, CM; Taylor, EM; Wootton, P	1
Arai, T; Fujii, Y; Hongo, T; Igarashi, Y; Kino, I; Mizuno, Y; Okamoto, K	1
Bleyer, WA; Geraci, JP; Geyer, JR; Hubbard, BA; Milstein, JM; Shaw, CM; Taylor, EM; Thornquist, M	1
Procter, PR	1
Bacci, G; Campanacci, M; Gherlinzoni, F; Manfrini, M; Normand, AR; Orlandi, M; Picci, P; Pignatti, G; Van Horn, JR	1
Harrison, PV	1
Clegg, DO; Lee, RG; Tolman, KG; Ward, JR	1
Grossman, RI; Littman, P; Packer, RJ; Rorke, LB; Siegel, KR; Sutton, LN	1
Beschorner, WE; Clark, AW; Patchell, RA; Santos, GW; White, CL	1
Schiodt, T; Zachariae, H	1
Hobson, RW; Kingry, RL; Muir, RW	1
Auerbach, R; Tobias, H	1
Heenan, PJ; Wright, JL	1
Aach, RD; Eisen, AZ; Grisham, JW; Reese, LT	1
Lamerton, LF	1
Chun, D; Ma, HK; Yip, SK	1
Belisario, JC; Kocsard, E; Kramer, H	1
Cox, JW; Frost, P; Kalser, M; Millard, MM; Suringa, DW; Weinstein, GD	1

Reviews

9 review(s) available for methotrexate and Necrosis

Article	Year
Febrile ulceronecrotic Mucha-Habermann disease: a case report and review of the literature. Acta dermato-venereologica, 2008, Volume: 88, Issue:4 Topics: Adult; Female; Fever; Humans; Methotrexate; Necrosis; Pityriasis; Pityriasis Lichenoides; Ulcer	2008
Necrotizing vasculitis--a 2009 update. Bulletin of the NYU hospital for joint diseases, 2009, Volume: 67, Issue:3 Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Behcet Syndrome; Churg-Strauss Syndrome; Evidence-Based Medicine; Female; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Male; Methotrexate; Microscopic Polyangiitis; Necrosis; Randomized Controlled Trials as Topic; Treatment Outcome; Vasculitis	2009
Primary NK/T cell lymphoma of the testis. A case report and review of the literature. Acta haematologica, 2003, Volume: 109, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cyclophosphamide; Doxorubicin; Fatal Outcome; Herpesvirus 4, Human; Humans; Immunohistochemistry; Immunophenotyping; In Situ Hybridization; Killer Cells, Natural; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Necrosis; Neoplasm Metastasis; Orchiectomy; Prednisone; Radiotherapy; Recurrence; RNA, Viral; Skin; Testicular Neoplasms; Thoracic Wall; Tomography, X-Ray Computed; Ultrasonography; Vincristine	2003
Transition of pityriasis lichenoides et varioliformis acuta to febrile ulceronecrotic Mucha-Habermann disease is associated with elevated serum tumour necrosis factor-alpha. The British journal of dermatology, 2005, Volume: 152, Issue:4 Topics: Administration, Oral; Child; Dermatologic Agents; Fever; Humans; Interleukin-2; Interleukin-4; Male; Methotrexate; Necrosis; Pityriasis Lichenoides; Skin Ulcer; Treatment Outcome; Tumor Necrosis Factor-alpha	2005
[Quality and quantity in hepatopathology. Diagnostic and clinically relevant grading for non-tumourous liver diseases]. Der Pathologe, 2008, Volume: 29, Issue:1 Topics: Fatty Liver; Female; Humans; Liver; Liver Diseases; Liver Transplantation; Male; Methotrexate; Necrosis	2008
Osteosarcoma in adolescents and young adults: new developments and controversies. The Mayo Clinic studies. Cancer treatment and research, 1993, Volume: 62 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Feasibility Studies; Female; Humans; Ifosfamide; Life Tables; Male; Methotrexate; Minnesota; Necrosis; Osteosarcoma; Pilot Projects; Survival Analysis; Treatment Outcome; Vincristine	1993
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta. Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:2 Pt 1 Topics: Adolescent; Fever; Humans; Male; Methotrexate; Necrosis; Pityriasis Lichenoides; Skin	1994
Methotrexate-associated appearance and rapid progression of rheumatoid nodules in systemic-onset juvenile rheumatoid arthritis. Arthritis and rheumatism, 1997, Volume: 40, Issue:1 Topics: Antirheumatic Agents; Arthritis, Juvenile; Child, Preschool; Clinical Protocols; Female; Humans; Methotrexate; Necrosis; Rheumatoid Nodule	1997
Drug-induced chronic hepatic disease. The Medical clinics of North America, 1979, Volume: 63, Issue:3 Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chronic Disease; Fatty Liver; Hemangioendothelioma; Hexestrol; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate; Necrosis; Oxyphenisatin Acetate	1979

Trials

10 trial(s) available for methotrexate and Necrosis

Article	Year
Efficacy and Safety of ABBV-3373, a Novel Anti-Tumor Necrosis Factor Glucocorticoid Receptor Modulator Antibody-Drug Conjugate, in Adults with Moderate-to-Severe Rheumatoid Arthritis Despite Methotrexate Therapy: A Randomized, Double-Blind, Active-Control Arthritis & rheumatology (Hoboken, N.J.), 2023, Volume: 75, Issue:6 Topics: Adalimumab; Adult; Anaphylaxis; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Glucocorticoids; Humans; Methotrexate; Necrosis; Pharmaceutical Preparations; Receptors, Glucocorticoid; Receptors, Tumor Necrosis Factor; Treatment Outcome; Tumor Necrosis Factor Inhibitors	2023
Prognostic and predictive impact of central necrosis and fibrosis in early breast cancer: results from two International Breast Cancer Study Group randomized trials of chemoendocrine adjuvant therapy. Breast cancer research and treatment, 2010, Volume: 121, Issue:1 Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fibrosis; Fluorouracil; Goserelin; Humans; Methotrexate; Necrosis; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome	2010
Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities: the recent experience at the Rizzoli Institute. Cancer treatment and research, 1993, Volume: 62 Topics: Actuarial Analysis; Adolescent; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Extremities; Female; Humans; Italy; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Salvage Therapy; Survival Analysis	1993
Osteosarcoma in adolescents and young adults: new developments and controversies. The Mayo Clinic studies. Cancer treatment and research, 1993, Volume: 62 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Feasibility Studies; Female; Humans; Ifosfamide; Life Tables; Male; Methotrexate; Minnesota; Necrosis; Osteosarcoma; Pilot Projects; Survival Analysis; Treatment Outcome; Vincristine	1993
The combination of ursodeoxycholic acid and methotrexate for primary biliary cirrhosis is not better than ursodeoxycholic acid alone. Journal of hepatology, 1997, Volume: 27, Issue:1 Topics: Adult; Aged; Cholagogues and Choleretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Necrosis; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid	1997
Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Time Factors; Treatment Outcome	1998
Local host response in osteosarcoma after chemotherapy referred to radiographs, CT, tumour necrosis and patient survival. Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:10 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Infant; Infant, Newborn; Male; Mesna; Methotrexate; Middle Aged; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Predictive Value of Tests; Prognosis; Tomography, X-Ray Computed	1998
High-dose methotrexate and HELP [Holoxan (ifosfamide), eldesine (vindesine), platinum]--doxorubicin in non-metastatic osteosarcoma of the extremity: a French multicentre pilot study. Fédération Nationale des Centres de Lutte contre le Cancer and Société F Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:9 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Disease-Free Survival; Doxorubicin; Female; France; Humans; Ifosfamide; Male; Methotrexate; Necrosis; Osteosarcoma; Pilot Projects; Prognosis; Survival Rate; Time Factors; Vindesine	1999
Cyclosporine, methotrexate, and methylprednisolone compared with cyclosporine and methotrexate for the prevention of graft-versus-host disease in bone marrow transplantation from HLA-identical sibling donor: a prospective randomized study. Blood, 2000, Oct-01, Volume: 96, Issue:7 Topics: Acute Disease; Adolescent; Adult; Blood Transfusion; Bone and Bones; Bone Marrow Transplantation; Cause of Death; Chronic Disease; Cyclosporine; Female; Graft vs Host Disease; Hematologic Neoplasms; Histocompatibility Testing; Hospitalization; Humans; Infections; Male; Methotrexate; Methylprednisolone; Middle Aged; Necrosis; Nuclear Family; Prospective Studies; Recurrence; Survival Rate	2000
Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Clinical Protocols; Combined Modality Therapy; Doxorubicin; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intra-Arterial; Italy; Methotrexate; Necrosis; Osteosarcoma; Osteotomy; Postoperative Care; Preoperative Care; Prostheses and Implants; Survival Rate; Telangiectasis	1991

Other Studies

137 other study(ies) available for methotrexate and Necrosis

Article	Year
Examining the potential direct cardiovascular benefit of tumor-necrosis factor inhibitor in rheumatoid arthritis: Natural and controlled direct effect analyses. Pharmacoepidemiology and drug safety, 2023, Volume: 32, Issue:4 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Humans; Methotrexate; Necrosis; Neoplasms; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha	2023
Primary hepatic methotrexate-associated lymphoproliferative disorder associated with Epstein-Barr virus reactivation and accompanied by spontaneous necrosis: A case report. Medicine, 2022, Nov-25, Volume: 101, Issue:47 Topics: Antigens, CD; Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Liver; Lymphoproliferative Disorders; Methotrexate; Middle Aged; Necrosis	2022
Apoptosis versus necrosis in tubal ectopic pregnancies following Methotrexate. International journal of experimental pathology, 2023, Volume: 104, Issue:2 Topics: Abortifacient Agents, Nonsteroidal; Animals; Apoptosis; Female; Humans; Methotrexate; Necrosis; Pregnancy; Pregnancy, Ectopic; Rabbits	2023
Children with inflammatory bowel disease already have an altered arterial pulse wave. European journal of pediatrics, 2023, Volume: 182, Issue:4 Topics: Adolescent; Adult; Blood Pressure; Carotid Intima-Media Thickness; Case-Control Studies; Child; Female; Humans; Inflammatory Bowel Diseases; Male; Methotrexate; Necrosis; Pulse Wave Analysis; Vascular Stiffness	2023
Impact of chemotherapy-induced necrosis on event-free and overall survival after preoperative MAP chemotherapy in patients with primary high-grade localized osteosarcoma. The bone & joint journal, 2020, Volume: 102-B, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Correlation of Data; Disease-Free Survival; Doxorubicin; Female; Humans; Male; Methotrexate; Necrosis; Neoadjuvant Therapy; Osteosarcoma; Preoperative Period; Retrospective Studies; Survival Rate; Young Adult	2020
Methotrexate-induced epidermal necrosis in a child with osteosarcoma. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020, Volume: 18, Issue:9 Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Humans; Male; Methotrexate; Necrosis; Osteosarcoma	2020
Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways. Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:5 Topics: Alanine; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Janus Kinase 1; Liver; Male; Methotrexate; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Quinolones; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA	2020
High-dose methotrexate-induced epidermal necrosis in two pediatric patients. Pediatric dermatology, 2021, Volume: 38, Issue:3 Topics: Child; Child, Preschool; Female; Humans; Leucovorin; Male; Methotrexate; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Skin Diseases	2021
Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity. PloS one, 2017, Volume: 12, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Liver; Male; Methotrexate; Mice; Necrosis; NF-kappa B; Oxidative Stress; Real-Time Polymerase Chain Reaction; Sitagliptin Phosphate	2017
Methotrexate-induced epidermal necrosis: A case series of 24 patients. Journal of the American Academy of Dermatology, 2017, Volume: 77, Issue:2 Topics: Adult; Age Factors; Aged; Body Surface Area; Case-Control Studies; Drug Eruptions; Epidermis; Female; Folic Acid Antagonists; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Necrosis; Prognosis; Renal Insufficiency, Chronic; Survival Rate; Vitamin B Complex	2017
Methotrexate carried in lipid core nanoparticles reduces myocardial infarction size and improves cardiac function in rats. International journal of nanomedicine, 2017, Volume: 12 Topics: Animals; Apoptosis; Coronary Vessels; Lipids; Male; Methotrexate; Myocardial Infarction; Myocardium; Nanoparticles; Necrosis; Rats, Wistar; Vascular Endothelial Growth Factor A; Ventricular Function, Left; Ventricular Remodeling	2017
Painful, violaceous plaques in a patient with pruritus. Clinical and experimental dermatology, 2017, Volume: 42, Issue:8 Topics: Humans; Kidney Failure, Chronic; Male; Methotrexate; Middle Aged; Necrosis; Pain; Pancytopenia; Pruritus; Skin; Skin Diseases; Thigh	2017
Spirulina ameliorates methotrexate hepatotoxicity via antioxidant, immune stimulation, and proinflammatory cytokines and apoptotic proteins modulation. Life sciences, 2018, Mar-01, Volume: 196 Topics: Adjuvants, Immunologic; Animals; Antimetabolites; Antioxidants; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Cytokines; Leukocyte Count; Lipid Peroxidation; Male; Methotrexate; Necrosis; Plant Extracts; Rats; Rats, Wistar; Spirulina; Spleen	2018
A young man with necrotic skin lesions. Clinical and experimental dermatology, 2019, Volume: 44, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Fever; Humans; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Pityriasis Lichenoides; Prednisolone; Skin; Skin Diseases; Treatment Outcome	2019
A Woman With Severe Rash. Annals of emergency medicine, 2018, Volume: 72, Issue:2 Topics: Aged; Anti-Bacterial Agents; Exanthema; Febrile Neutropenia; Female; Folic Acid; Humans; Leucovorin; Methotrexate; Necrosis; Pancytopenia; Rheumatic Fever; Skin; Stomatitis	2018
Successful Treatment of Necrotizing Retinitis with Epstein-Barr Virus-Positive Ocular Fluid by Intravitreal Methotrexate Injection. Ocular immunology and inflammation, 2020, May-18, Volume: 28, Issue:4 Topics: Aged, 80 and over; Aqueous Humor; DNA, Viral; Epstein-Barr Virus Infections; Eye Infections, Viral; Female; Follow-Up Studies; Herpesvirus 4, Human; Humans; Intravitreal Injections; Methotrexate; Necrosis; Nucleic Acid Synthesis Inhibitors; Retinitis; Retrospective Studies; Treatment Outcome	2020
Fatal neurological side-effects with necrosis of spinal cord following nelarabine treatment in a child with relapsed T-cell acute lymphoblastic leukemia. American journal of hematology, 2013, Volume: 88, Issue:12 Topics: Antimetabolites, Antineoplastic; Arabinonucleosides; Cerebellum; Child; Cyclophosphamide; Cytarabine; Etoposide; Fatal Outcome; Guillain-Barre Syndrome; Humans; Magnetic Resonance Imaging; Male; Medulla Oblongata; Methotrexate; Necrosis; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Seizures; Spinal Cord	2013
[Immune-mediated necrotizing myopathy associated with antibodies to hydroxy-methyl-glutaryl-coenzyme A reductase]. La Revue de medecine interne, 2014, Volume: 35, Issue:8 Topics: Autoantibodies; Autoimmune Diseases; Biomarkers; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Methotrexate; Middle Aged; Muscle, Skeletal; Muscular Diseases; Necrosis; Risk Factors; Time Factors; Treatment Outcome	2014
Multiple intracranial nodules associated with rheumatoid arthritis: case report. Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4 Topics: Aged; Biopsy; Brain Diseases; Cerebellopontine Angle; Choroid Plexus; Female; Gait Disorders, Neurologic; Hippocampus; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Methotrexate; Necrosis; Neuroimaging; Prednisolone; Radiography; Rheumatoid Nodule	2014
Febrile ulceronecrotic Mucha-Habermann disease. Cutis, 2013, Volume: 92, Issue:5 Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents; Female; Fever; Humans; Immunosuppressive Agents; Methotrexate; Methylprednisolone; Necrosis; Pityriasis Lichenoides; Recurrence; Skin; Skin Ulcer	2013
Widespread skin necrosis due to methotrexate overdose in a patient with CKD. Kidney international, 2014, Volume: 85, Issue:3 Topics: Drug Overdose; Humans; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Renal Insufficiency, Chronic; Skin	2014
Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition. Biochemical pharmacology, 2014, Aug-01, Volume: 90, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; Humans; Isoquinolines; Methotrexate; Mice; Mice, Inbred Strains; Necrosis; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Basal Cell; Random Allocation; Tetrahydrofolate Dehydrogenase; Tumor Burden	2014
Methotrexate myelopathy with extensive transverse necrosis: report of an autopsy case. Neuropathology : official journal of the Japanese Society of Neuropathology, 2014, Volume: 34, Issue:6 Topics: Aged; Female; Folic Acid Antagonists; Humans; Methotrexate; Necrosis; Spinal Cord Diseases; Waldenstrom Macroglobulinemia	2014
Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats? Acta cirurgica brasileira, 2015, Volume: 30, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Interleukin-1beta; Liver; Male; Malondialdehyde; Methotrexate; Necrosis; Peroxidase; Random Allocation; Rats, Wistar; Reproducibility of Results; Thioctic Acid; Treatment Outcome; Tumor Necrosis Factor-alpha	2015
Tongue necrosis in giant-cell arteritis. QJM : monthly journal of the Association of Physicians, 2015, Volume: 108, Issue:10 Topics: Aged; Biopsy; Diphosphonates; Female; Giant Cell Arteritis; Humans; Methotrexate; Necrosis; Prednisone; Tongue; Vitamin D	2015
Febrile ulceronecrotic Mucha-Habermann disease in an 8-year-old boy responding to methotrexate. International journal of dermatology, 2016, Volume: 55, Issue:11 Topics: Child; Dermatologic Agents; Fever; Humans; Male; Methotrexate; Necrosis; Pityriasis Lichenoides; Skin; Skin Ulcer	2016
Protective Effects of Vitamin E on Methotrexate-Induced Jejunal Mucosal Damage in Rats. Analytical and quantitative cytopathology and histopathology, 2016, Volume: 38, Issue:2 Topics: Animals; Antioxidants; Biomarkers; Cytoprotection; Disease Models, Animal; Gastrointestinal Hemorrhage; Glutathione Peroxidase; Intestinal Mucosa; Jejunal Diseases; Jejunum; Male; Malondialdehyde; Methotrexate; Necrosis; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Time Factors; Vitamin E	2016
Tacrolimus in combination with methotrexate and corticosteroid for the treatment of child-onset anti-signal recognition particle antibody-positive necrotizing myopathy. Scandinavian journal of rheumatology, 2017, Volume: 46, Issue:5 Topics: Age of Onset; Autoantibodies; Biopsy; Child; Drug Administration Schedule; Drug Therapy, Combination; Glucocorticoids; Humans; Male; Methotrexate; Muscle, Skeletal; Muscular Diseases; Necrosis; Signal Recognition Particle; Tacrolimus; Treatment Outcome	2017
[Primary cutaneous manifestation of Wegener's granulomatosis]. Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:27 Topics: Antibodies, Antineutrophil Cytoplasmic; Biopsy; Drug Therapy, Combination; Glomerulonephritis; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Leg Dermatoses; Leukocyte Count; Male; Methotrexate; Middle Aged; Myeloblastin; Necrosis; Prednisolone; Skin; Skin Diseases, Vascular	2008
Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons. Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 54, Issue:2 Topics: Acidosis; Amiloride; Animals; Antimetabolites, Antineoplastic; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Fluorometry; Marine Toxins; Methotrexate; Necrosis; Neurons; Neuroprotective Agents; Oxocins; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sodium-Hydrogen Exchangers	2009
Febrile ulceronecrotic Mucha-Habermann disease: a rare dermatological emergency. Clinical and experimental dermatology, 2009, Volume: 34, Issue:8 Topics: Adolescent; Dermatologic Agents; Fever; Humans; Male; Methotrexate; Necrosis; Pityriasis Lichenoides; Recurrence; Skin Ulcer	2009
Rheumatoid nodule and combined pulmonary carcinoma: topographic correlations; a case report and review of the literature. Histology and histopathology, 2011, Volume: 26, Issue:3 Topics: Adenocarcinoma; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma; Carcinoma, Squamous Cell; Coloring Agents; Cortisone; Humans; Immunohistochemistry; Lung Neoplasms; Lymph Nodes; Male; Methotrexate; Middle Aged; Necrosis; Rheumatoid Nodule; Tumor Necrosis Factor-alpha	2011
Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia. Pathology, 2011, Volume: 43, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Enterocolitis, Pseudomembranous; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Necrosis; Recovery of Function; Remission Induction; Tretinoin; Vancomycin	2011
Acute methotrexate toxicity seen as plaque psoriasis ulceration and necrosis: A diagnostic clue. Dermatology online journal, 2011, Nov-15, Volume: 17, Issue:11 Topics: Acute Kidney Injury; Adult; Azithromycin; Biopsy; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Mucositis; Necrosis; Pancytopenia; Plasma; Psoriasis; Recombinant Proteins; Self Medication; Skin Ulcer; Trimethoprim, Sulfamethoxazole Drug Combination	2011
CHEMOTHERAPY OF FIVE SUPRATENTORIAL MALIGNANT GLIOMAS WITH INTRA-ARTERIAL INFUSION OF METHOTREXATE. Acta chirurgica Scandinavica, 1964, Volume: 127 Topics: Aphasia; Brain Neoplasms; Carotid Arteries; Cerebral Angiography; Drug Therapy; Glioma; Humans; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Necrosis; Paralysis; Parietal Lobe; Surgical Procedures, Operative; Temporal Lobe	1964
FOLIC-ACID ANTAGONISTS IN TREATMENT OF PSORIASIS. British medical journal, 1965, Jul-17, Volume: 2, Issue:5454 Topics: Drug Therapy; Duodenal Ulcer; Folic Acid Antagonists; Kidney Diseases; Kidney Tubules; Leukopenia; Melena; Methotrexate; Mouth Diseases; Necrosis; Pathology; Psoriasis; Toxicology	1965
A case of edematous dermatomyositis. The Journal of rheumatology, 2003, Volume: 30, Issue:12 Topics: Aged; Biopsy; Dermatomyositis; Drug Therapy, Combination; Edema; Electromyography; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Methotrexate; Muscle Fibers, Skeletal; Muscle, Skeletal; Necrosis; Prednisone; Pulmonary Embolism; Remission Induction	2003
Methotrexate levels and outcome in osteosarcoma. Pediatric blood & cancer, 2005, Jun-15, Volume: 44, Issue:7 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Humans; Male; Methotrexate; Necrosis; Osteosarcoma; Prognosis; Prospective Studies; Treatment Outcome	2005
An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer research, 2005, Mar-01, Volume: 65, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Mice; Mice, SCID; Necrosis; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Prognosis; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Survival Rate; Transplantation, Heterologous; Treatment Outcome	2005
Methotrexate induces cell swelling and necrosis in renal tubular cells. Pediatric blood & cancer, 2006, May-01, Volume: 46, Issue:5 Topics: Amiloride; Animals; Antimetabolites, Antineoplastic; Cell Size; Cell Survival; Kidney Tubules, Proximal; LLC-PK1 Cells; Methotrexate; Necrosis; Sodium Channel Blockers; Swine	2006
Angry fat. The Journal of rheumatology, 2006, Volume: 33, Issue:5 Topics: Adipocytes; Adult; Anti-Inflammatory Agents; Cytokines; Drug Therapy, Combination; Humans; Male; Methotrexate; Methylprednisolone; Muscle, Skeletal; Necrosis; Panniculitis; Prednisone; T-Lymphocytes	2006
Multifocal necrotizing leukoencephalopathy: An unusual complication of acute leukemia. Archives of neurology, 2006, Volume: 63, Issue:7 Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis; Vincristine	2006
Calpain inhibitors and antioxidants act synergistically to prevent cell necrosis: effects of the novel dual inhibitors (cysteine protease inhibitor and antioxidant) BN 82204 and its pro-drug BN 82270. Journal of neurochemistry, 2006, Volume: 98, Issue:4 Topics: Animals; Antioxidants; Calpain; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dinoprost; Drug Synergism; Humans; Lipid Peroxidation; Methotrexate; Necrosis; Nucleic Acid Synthesis Inhibitors; Phenothiazines; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Serine Endopeptidases	2006
Disseminated necrotizing leukoencephalopathy following chemoradiation therapy for acute lymphoblastic leukemia. Radiation medicine, 2006, Volume: 24, Issue:7 Topics: Antimetabolites, Antineoplastic; Brain; Brain Diseases; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed	2006
[Three cases of necrotizing pneumonia by pseudomonas aeruginosa infection in hematological malignancy, including dead and alive cases]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Hematologic Neoplasms; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Necrosis; Neutropenia; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Severity of Illness Index	2007
[Progressive epidermal and mucosal skin lesions in a patient with rheumatoid arthritis]. Praxis, 2007, May-16, Volume: 96, Issue:20 Topics: Administration, Oral; Arthritis, Rheumatoid; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunosuppressive Agents; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Necrosis; Prednisone; Stevens-Johnson Syndrome; Stomatitis, Aphthous	2007
Intravenous immunoglobulins: a valuable asset in the treatment of a case of septic febrile ulceronecrotic Mucha-Habermann disease. Dermatology (Basel, Switzerland), 2007, Volume: 215, Issue:2 Topics: Adolescent; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Immunosuppressive Agents; Methotrexate; Necrosis; Pityriasis Lichenoides; Prednisolone; Sepsis	2007
[Spontaneous tongue necrosis consecutive to rheumatoid hyperviscosity syndrome. A case report and literature review]. Laryngo- rhino- otologie, 2008, Volume: 87, Issue:1 Topics: Aged; Arthritis, Rheumatoid; Blood Viscosity; Cortisone; Diagnosis, Differential; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypergammaglobulinemia; Immunosuppressive Agents; Ischemia; Male; Methotrexate; Necrosis; Regional Blood Flow; Syndrome; Tongue	2008
Atypical acute graft-versus-host disease. The American Journal of dermatopathology, 2007, Volume: 29, Issue:6 Topics: Acute Disease; Adult; Bone Marrow Transplantation; Cyclosporine; Erythema; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Skin Diseases; Treatment Outcome	2007
[Necrotizing systemic sarcoidosis with pulmonary and central nervous system involvement]. Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1 Topics: Adult; Antitubercular Agents; Brain Diseases; Cognition Disorders; Diagnostic Errors; Epilepsy, Tonic-Clonic; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Necrosis; Prednisone; Remission Induction; Sarcoidosis; Sarcoidosis, Pulmonary; Tuberculosis, Pulmonary; Urinary Incontinence; Vertigo	2008
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1984. Childhood leukemia with progressive neurologic deterioration. The New England journal of medicine, 1984, Sep-06, Volume: 311, Issue:10 Topics: Adolescent; Amygdala; Brain; Brain Diseases; Hippocampus; Humans; Leukemia, Lymphoid; Male; Methotrexate; Necrosis; Radiography; Radiotherapy; Spinal Cord; Spinal Cord Diseases	1984
Vascular changes of methotrexate-related disseminated necrotizing leukoencephalopathy. Acta neuropathologica, 1984, Volume: 65, Issue:2 Topics: Adult; Arteries; Axons; Brain; Child; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukoencephalopathy, Progressive Multifocal; Male; Meningeal Neoplasms; Methotrexate; Necrosis; Veins	1984
Chronic methotrexate toxicity to the central nervous system. Clinical bulletin, 1980, Volume: 10, Issue:2 Topics: Adult; Brain; Brain Diseases; Brain Neoplasms; Child; Humans; Injections, Intravenous; Injections, Spinal; Methotrexate; Necrosis; Radiation Dosage; Syndrome	1980
Necrotising leucoencephalopathy associated with intrathecal/intraventricular methotrexate therapy. The Medical journal of Australia, 1982, Sep-18, Volume: 2, Issue:6 Topics: Adolescent; Adult; Brain; Brain Diseases; Female; Humans; Injections, Intraventricular; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Necrosis	1982
Necrotizing myelopathy associated with acute lymphoblastic leukemia. Case report and review of literature. Acta neuropathologica, 1980, Volume: 49, Issue:3 Topics: Adolescent; Autopsy; Humans; Leukemia, Lymphoid; Male; Methotrexate; Necrosis; Spinal Cord Diseases	1980
Disseminated necrotizing leukoencephalopathy. Acta pathologica japonica, 1980, Volume: 30, Issue:4 Topics: Adult; Axons; Humans; Leukemia, Myeloid; Leukoencephalopathy, Progressive Multifocal; Male; Methotrexate; Necrosis	1980
Neurologic sequelae of methotrexate and ionizing radiation: a new classification. Cancer treatment reports, 1981, Volume: 65 Suppl 1 Topics: Adolescent; Adult; Brain; Brain Diseases; Child, Preschool; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Necrosis; Radiotherapy; Radiotherapy Dosage; Systems Theory; Time Factors	1981
Calcified cerebral necrosis following ALL therapy. Journal of cancer research and clinical oncology, 1981, Volume: 102, Issue:1 Topics: Adolescent; Brain; Calcinosis; Female; Humans; Leukemia, Lymphoid; Methotrexate; Necrosis; Radiotherapy	1981
A case of infantile febrile psoriasiform dermatitis. Pediatric dermatology, 1995, Volume: 12, Issue:1 Topics: Dermatitis; Diagnosis, Differential; Epidermis; Humans; Infant; Keratinocytes; Lichenoid Eruptions; Lymphocytosis; Male; Methotrexate; Necrosis; Periodicity; Psoriasis; Skin; Staphylococcus aureus; Transaminases	1995
Detailed immunohistologic evaluation of a methotrexate-induced nodule. Archives of pathology & laboratory medicine, 1994, Volume: 118, Issue:12 Topics: Arthritis, Rheumatoid; CD4-CD8 Ratio; HLA-D Antigens; Humans; Immunohistochemistry; Male; Methotrexate; Middle Aged; Necrosis	1994
Hyperthermic isolated perfusion using cisplatin for treatment of the extremities. Cancer treatment and research, 1993, Volume: 62 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Femoral Neoplasms; Fibula; Follow-Up Studies; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Male; Methotrexate; Necrosis; Osteosarcoma; Tibia; Tissue Distribution; Treatment Outcome	1993
Fulminant hepatic failure after methotrexate and PUVA therapy for psoriasis. Journal of clinical gastroenterology, 1993, Volume: 17, Issue:4 Topics: Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; PUVA Therapy	1993
[Correlation of serial MRI and histological findings following intra-tumor local chemotherapy for malignant brain tumor]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2 Topics: Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Cobalt Radioisotopes; Doxorubicin; Drug Administration Schedule; Female; Glioblastoma; Glioma; Humans; Injections, Intralesional; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis	1994
Methotrexate induced brain necrosis and severe leukoencephalopathy due to disconnection of an Ommaya device. Journal of neuro-oncology, 1993, Volume: 15, Issue:3 Topics: Brain; Breast Neoplasms; Diffuse Cerebral Sclerosis of Schilder; Equipment Safety; Female; Humans; Iatrogenic Disease; Injections, Intraventricular; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Necrosis	1993
Fatal brain stem necrosis after standard posterior fossa radiation and aggressive chemotherapy for metastatic medulloblastoma. Cancer, 1993, Jun-15, Volume: 71, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Stem; Cerebellar Neoplasms; Child, Preschool; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Female; Humans; Medulloblastoma; Methotrexate; Necrosis; Neoplasm Recurrence, Local; Radiotherapy, High-Energy	1993
Histological findings in heart grafts after orthotopic pig to baboon cardiac transplantation. Transplantation proceedings, 1996, Volume: 28, Issue:2 Topics: Animals; Animals, Newborn; Cyclosporine; Edema; Female; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Hemorrhage; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Papio; Splenectomy; Swine; Tacrolimus; Time Factors; Transplantation, Heterologous	1996
Musculoskeletal tumour disorders. Comprehensive therapy, 1996, Volume: 22, Issue:1 Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Humans; Methotrexate; Necrosis; Osteosarcoma	1996
Fingertip necrosis during chemotherapy with bleomycin, vincristine and methotrexate for HIV-related Kaposi's sarcoma. The British journal of dermatology, 1996, Volume: 134, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Fingers; HIV Infections; Humans; Male; Methotrexate; Necrosis; Raynaud Disease; Sarcoma, Kaposi; Vincristine	1996
Conservative treatment using a methotrexate-lipiodol emulsion containing non-ionic contrast medium for a cervical ectopic pregnancy. Human reproduction (Oxford, England), 1997, Volume: 12, Issue:12 Topics: Adult; Cervix Uteri; Chorionic Gonadotropin, beta Subunit, Human; Contrast Media; Emulsions; Female; Humans; Iodized Oil; Iopamidol; Methotrexate; Necrosis; Pregnancy; Pregnancy, Ectopic; Sonication; Ultrasonography	1997
Intraventricular chemotherapy. Journal of neurosurgery, 1998, Volume: 89, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain Diseases; Catheters, Indwelling; Cerebral Ventricles; Humans; Meningeal Neoplasms; Meningitis, Aseptic; Methotrexate; Necrosis	1998
The histologic effects of low-dose methotrexate therapy for primary biliary cirrhosis. Archives of pathology & laboratory medicine, 1998, Volume: 122, Issue:4 Topics: Biopsy; Fibrosis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Methotrexate; Necrosis	1998
Necrosis of myometrial choriocarcinoma with fulminating sepsis complicating chemotherapy for trophoblastic tumor. Gynecologic oncology, 1998, Volume: 70, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Methotrexate; Myometrium; Necrosis; Neoplasms, Multiple Primary; Pregnancy; Remission Induction; Sepsis; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine	1998
Evaluation of apoptosis and necrosis induction in cultured cells of lung carcinomas under effect of cytostatic drugs in vitro. Folia histochemica et cytobiologica, 1999, Volume: 37, Issue:2 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bleomycin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Epirubicin; Etoposide; Humans; Lung Neoplasms; Methotrexate; Necrosis; Tumor Cells, Cultured; Vinblastine; Vincristine	1999
Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy. AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:3 Topics: Adolescent; Adult; Antineoplastic Agents; Brain Diseases; Cerebral Cortex; Cyclosporine; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis; Tacrolimus; Tomography, X-Ray Computed; Vincristine	2000
Patients with acute skin loss: are they best managed on a burns unit? Annals of the Royal College of Surgeons of England, 2001, Volume: 83, Issue:1 Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Burn Units; Critical Care; Drug Eruptions; Fasciitis, Necrotizing; Female; Humans; London; Male; Methotrexate; Middle Aged; Necrosis; Sepsis; Skin Diseases; Stevens-Johnson Syndrome	2001
Radiation myelitis in a 5-year-old girl. Journal of child neurology, 2002, Volume: 17, Issue:3 Topics: Child, Preschool; Chronic Disease; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Methotrexate; Muscle, Skeletal; Myelitis; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation Dosage; Radiation Injuries; Radiculopathy; Radiotherapy	2002
A peculiar brain scan pattern in necrotizing leukoencephalopathy after treatment for CNS-leukaemia. Clinical neurology and neurosurgery, 1979, Volume: 81, Issue:3 Topics: Brain; Brain Neoplasms; Cerebral Ventricles; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Necrosis; Radionuclide Imaging	1979
[Skull cap necrosis with simultaneous radio-chemotherapy using the Ommaya reservoir]. Strahlentherapie. Sonderbande, 1978, Volume: 75 Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Drug Therapy; Female; Glioblastoma; Humans; Male; Methotrexate; Necrosis; Osteomyelitis; Osteoradionecrosis; Radiation Injuries; Radioisotope Teletherapy; Scalp	1978
Methotrexate encephalopathy. A neuropathologic study. Human pathology, 1978, Volume: 9, Issue:6 Topics: Brain; Brain Diseases; Child, Preschool; Female; Gliosis; Humans; Leukemia, Lymphoid; Male; Meninges; Methotrexate; Necrosis	1978
Pulpal responses to operative procedures in rats receiving systemic methotrexate. Oral surgery, oral medicine, and oral pathology, 1979, Volume: 48, Issue:5 Topics: Animals; Dental Cavity Preparation; Dental Pulp; Dental Pulp Exposure; Female; Male; Methotrexate; Necrosis; Neutrophils; Odontoblasts; Rats; Wound Healing	1979
Primary osteogenic sarcoma: pathologic aspects in 20 patients after treatment with chemotherapy en bloc resection, and prosthetic bone replacement. Archives of pathology & laboratory medicine, 1977, Volume: 101, Issue:1 Topics: Adolescent; Adult; Amputation, Surgical; Bone Neoplasms; Child; Drug Therapy, Combination; Female; Femoral Neoplasms; Humans; Leucovorin; Male; Methotrexate; Necrosis; Osteocytes; Osteosarcoma; Tibia; Vincristine	1977
Enzymatic fluorometry for estimating serum total bile acid concentration. JAMA, 1979, May-11, Volume: 241, Issue:19 Topics: 3-Hydroxysteroid Dehydrogenases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Fasting; Fatty Liver; Female; Fluorometry; Hepatitis, Viral, Human; Humans; Liver; Liver Diseases; Male; Methotrexate; Necrosis; Sarcoidosis	1979
Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma. Surgical neurology, 1977, Volume: 7, Issue:3 Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; Humans; Methotrexate; Necrosis; Neoplasm Metastasis; Pregnancy; Radiation Injuries; Radiotherapy; Tomography, X-Ray Computed; Uterine Neoplasms	1977
[Radiation effects in brain and spinal cord (author's transl)]. Strahlentherapie, 1978, Volume: 154, Issue:9 Topics: Age Factors; Brain; Humans; Mathematics; Methotrexate; Necrosis; Radiation Injuries; Radiotherapy Dosage; Sex Factors; Spinal Cord	1978
Computed tomographic appearance of methotrexate-induced necrotizing leukoencephalopathy. Radiology, 1977, Volume: 122, Issue:2 Topics: Adult; Brain Abscess; Brain Diseases; Diagnosis, Differential; Female; Humans; Methotrexate; Necrosis; Tomography, X-Ray Computed	1977
Hepatotoxicity in Wistar rats following chronic methotrexate administration: a model of human reaction. Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4 Topics: Age Factors; Animals; Body Weight; Bone Marrow; Digestive System; Fatty Liver; Humans; Liver; Lung; Lymphocytes; Male; Methotrexate; Necrosis; Rats; Skin; Spleen; Testis; Triglycerides	1977
Radiation necrosis of the scalp: a complication of cranial irradiation and methotrexate. Radiology, 1977, Volume: 124, Issue:3 Topics: Child, Preschool; Humans; Leukemia; Male; Methotrexate; Necrosis; Radiation Injuries; Radiotherapy; Scalp Dermatoses	1977
Morphogenesis of fibrosis and cirrhosis in methotrexate-treated patients with psoriasis. The American journal of surgical pathology, 1977, Volume: 1, Issue:3 Topics: Adult; Aged; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis	1977
[Acute necrotizing colitis in a psoriatic treated by methotrexát (author's transl)]. Ceskoslovenska dermatologie, 1977, Volume: 52, Issue:4 Topics: Adult; Colitis, Ulcerative; Female; Humans; Methotrexate; Necrosis; Psoriasis	1977
Leukoencephalopathy following combined therapy of central nervous system leukemia and lymphoma. Acta neuropathologica. Supplementum, 1975, Volume: Suppl 6 Topics: Axons; Brain; Brain Diseases; Burkitt Lymphoma; Central Nervous System Diseases; Child; Cytarabine; Humans; Injections, Spinal; Leukemia, Lymphoid; Meninges; Methotrexate; Necrosis; Radiotherapy	1975
Liver disease caused by medicinal agents. The Medical clinics of North America, 1975, Volume: 59, Issue:4 Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Halothane; Humans; Isoniazid; Jaundice; Liver; Liver Cirrhosis; Metabolism, Inborn Errors; Methotrexate; Methoxyflurane; Methyldopa; Necrosis; Novobiocin	1975
Methotrexate effects on enteric mucosa liver and pancreas of normal and bled rats. European journal of cancer, 1975, Volume: 11, Issue:5 Topics: Anemia; Animals; Intestinal Mucosa; Lipids; Liver; Male; Methotrexate; Necrosis; Pancreas; Rats; Time Factors	1975
The lethal actions of antitumor agents in proliferating cell systems in vivo. The American journal of pathology, 1975, Volume: 81, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Survival; Cytarabine; DNA; DNA Replication; Epithelial Cells; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Lysosomes; Methotrexate; Mice; Mitosis; Necrosis; Poly I-C; RNA; Vacuoles	1975
Necrotizing mesenteric vasculitis after longstanding cutaneous polyarteritis nodosa. The Journal of rheumatology, 1992, Volume: 19, Issue:8 Topics: Adult; Azathioprine; Cyclophosphamide; Dapsone; Female; Humans; Mesenteric Arteries; Methotrexate; Necrosis; Plasmapheresis; Polyarteritis Nodosa; Potassium Iodide; Prednisone; Vasculitis	1992
Osmotic blood-brain barrier disruption and chemotherapy in the treatment of high grade malignant glioma: patient series and literature review. Journal of neuro-oncology, 1992, Volume: 12, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Follow-Up Studies; Glioma; Humans; Mannitol; Methotrexate; Necrosis; Procarbazine; Retrospective Studies; Technetium Tc 99m Pentetate; Tomography, X-Ray Computed	1992
Akinetic mutism in bilateral necrotizing leucoencephalopathy after radiation and chemotherapy: electrophysiological and autopsy findings. Journal of neurology, 1992, Volume: 239, Issue:3 Topics: Adult; Afferent Pathways; Akinetic Mutism; Alpha Rhythm; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Fossa, Posterior; Cranial Irradiation; Cyclophosphamide; Demyelinating Diseases; Doxorubicin; Electroencephalography; Evoked Potentials, Somatosensory; Female; Fluorouracil; Humans; Mastectomy; Methotrexate; Necrosis; Stereotyped Behavior	1992
Assessment of osteosarcoma response to preoperative chemotherapy using dynamic FLASH gadolinium-DTPA-enhanced magnetic resonance mapping. Investigative radiology, 1992, Volume: 27, Issue:5 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Contrast Media; Doxorubicin; Female; Gadolinium; Gadolinium DTPA; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Methotrexate; Necrosis; Organometallic Compounds; Osteosarcoma; Pentetic Acid; Preoperative Care	1992
Cerebrovascular effects and tumor kinetics after a single intratumoral injection of human recombinant interleukin-2 alone or in combination with intravenous chemotherapy in a rat model of glioma. Neurosurgery, 1992, Volume: 31, Issue:1 Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Combined Modality Therapy; Doxorubicin; Glioma; Humans; Injections, Intralesional; Interleukin-2; Methotrexate; Necrosis; Neoplasm Transplantation; Rats; Rats, Inbred F344; Recombinant Proteins; Vincristine	1992
[Intraparenchymal non-neoplastic residual masses after treatment of large-cell non-Hodgkin's lymphoma with intensive chemotherapy]. Medicina clinica, 1990, Mar-31, Volume: 94, Issue:12 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Fibrosis; Humans; Kidney; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Necrosis; Prednisone; Spleen; Vincristine	1990
IIB osteosarcoma. Current management, local control, and survival statistics--the Australian experience. Clinical orthopaedics and related research, 1991, Issue:270 Topics: Adolescent; Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Australia; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Injections, Intra-Arterial; Life Tables; Male; Methotrexate; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Neoplasm Staging; Osteosarcoma; Osteotomy; Postoperative Complications; Radiotherapy; Remission Induction; Survival Rate	1991
Brain lesions following combined treatment with methotrexate and craniospinal irradiation. Journal of neuro-oncology, 1991, Volume: 10, Issue:2 Topics: Adult; Aged; Brain Diseases; Brain Edema; Breast Neoplasms; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Demyelinating Diseases; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Male; Meningeal Neoplasms; Mental Disorders; Methotrexate; Middle Aged; Necrosis	1991
Zürich experience with preoperative, high dose methotrexate-containing chemotherapy in patients with extremity osteosarcomas (OSA). Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:7 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Necrosis; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Survival Rate	1991
Tissue effects of methotrexate injected into the uterine horn of pregnant female rats. Human reproduction (Oxford, England), 1991, Volume: 6, Issue:4 Topics: Animals; Female; Methotrexate; Necrosis; Ovary; Oviducts; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Sodium Chloride; Uterus	1991
Hepatotoxicity in a rat model caused by orally administered methotrexate. Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:5 Topics: Administration, Oral; Alanine Transaminase; Animals; Dose-Response Relationship, Drug; Liver; Male; Methotrexate; Necrosis; Rats; Rats, Inbred Strains	1991
Stroke-like syndrome, mineralizing microangiopathy, and neuroaxonal dystrophy following intrathecal methotrexate therapy. Neurology, 1991, Volume: 41, Issue:11 Topics: Adult; Axons; Brain; Cerebrovascular Disorders; Female; Humans; Injections, Spinal; Methotrexate; Microcirculation; Necrosis; Neurons; Syndrome	1991
[Chemotherapeutic pathomorphosis of breast cancer]. Sovetskaia meditsina, 1990, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cisplatin; Female; Fluorouracil; Humans; Lymph Node Excision; Mastectomy, Radical; Methotrexate; Mitosis; Necrosis; Polymorphism, Genetic	1990
[Focal cerebral necrosis caused by intraventricular chemotherapy with methotrexate]. Neuro-Chirurgie, 1991, Volume: 37, Issue:1 Topics: Brain; Brain Abscess; Brain Neoplasms; Cerebral Ventricles; Confusion; Diagnosis, Differential; Female; Hemiplegia; Humans; Infusion Pumps, Implantable; Leukoencephalopathy, Progressive Multifocal; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Necrosis	1991
Effect of preoperative chemotherapy on mastectomy for locally advanced breast cancer. The American surgeon, 1990, Volume: 56, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Hospitalization; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Necrosis; Postoperative Complications; Retrospective Studies; Skin; Surgical Flaps; Tamoxifen; Time Factors	1990
Hepatitis with bridging fibrosis and reversible hepatic insufficiency in a woman with rheumatoid arthritis taking methotrexate. Arthritis and rheumatism, 1990, Volume: 33, Issue:7 Topics: Arthritis, Rheumatoid; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Methotrexate; Middle Aged; Necrosis	1990
Transtentorial herniation caused by an intracranial mass lesion following high-dose methotrexate. The American journal of pediatric hematology/oncology, 1990,Summer, Volume: 12, Issue:2 Topics: Adolescent; Combined Modality Therapy; Encephalocele; Eye Neoplasms; Female; Humans; Infusions, Intravenous; Intracranial Pressure; Methotrexate; Necrosis; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Orbital Neoplasms; Osteosarcoma; Retinoblastoma	1990
Disparate histologic responses in simultaneously resected primary and metastatic osteosarcoma following intravenous neoadjuvant chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Vincristine	1987
[Disseminated necrotizing leukoencephalopathy accompanied with multiple calcium deposits following antineoplastic and radiation therapy in a case of intracranial germ cell tumor: computerized tomographical study]. No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Calcinosis; Child; Combined Modality Therapy; Humans; Injections, Intraventricular; Leukoencephalopathy, Progressive Multifocal; Male; Methotrexate; Necrosis; Neoplasms, Germ Cell and Embryonal; Radiation Injuries; Radiotherapy; Tomography, X-Ray Computed	1989
Methotrexate induced skin necrosis: a drug interaction with amiodarone? BMJ (Clinical research ed.), 1989, Oct-14, Volume: 299, Issue:6705 Topics: Aged; Amiodarone; Drug Interactions; Female; Humans; Methotrexate; Necrosis; Skin	1989
[Bone marrow necrosis in a patient with metastatic breast cancer in chemotherapy with chlorambucil, methotrexate and prednisone]. Onkologie, 1989, Volume: 12, Issue:1 Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chlorambucil; Female; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Necrosis; Prednisone	1989
Experimental study on subacute neurotoxicity of methotrexate in cats. Acta neuropathologica, 1989, Volume: 78, Issue:3 Topics: Animals; Cats; Cerebrospinal Fluid; Demyelinating Diseases; Disease Models, Animal; Drug Synergism; Female; Male; Methotrexate; Necrosis; Neurotoxins; Risk Factors	1989
Near fatal drug interactions with methotrexate given for psoriasis. British medical journal (Clinical research ed.), 1987, Sep-26, Volume: 295, Issue:6601 Topics: Aged; Aged, 80 and over; Drug Interactions; Female; Humans; Methotrexate; Naproxen; Necrosis; Pancytopenia; Psoriasis; Skin; Skin Ulcer; Trimethoprim	1987
Combination of hyperthermia and methotrexate in the treatment of transplanted Walker sarcoma. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:3 Topics: Animals; Combined Modality Therapy; Hyperthermia, Induced; Methotrexate; Necrosis; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Sarcoma, Experimental	1988
Death from chemotherapy in gestational trophoblastic disease. European journal of obstetrics, gynecology, and reproductive biology, 1988, Volume: 29, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Methotrexate; Necrosis; Pregnancy; Pulmonary Embolism; Uterine Neoplasms	1988
Reactivation of cutaneous radionecrosis associated with methotrexate therapy for psoriasis. Clinical and experimental dermatology, 1988, Volume: 13, Issue:5 Topics: Humans; Male; Methotrexate; Middle Aged; Necrosis; Radiodermatitis; Recurrence; Scrotum; Skin	1988
Rodent model of chemoradiotherapy-induced white matter necrosis. NCI monographs : a publication of the National Cancer Institute, 1988, Issue:6 Topics: Animals; Brain; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Methotrexate; Necrosis; Radiotherapy; Rats; Rats, Inbred Strains	1988
[Serial spectral EEG analysis in a patient with non-Hodgkin's lymphoma complicated by leukoencephalopathy induced by high-dose methotrexate]. Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 1 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Child, Preschool; Electroencephalography; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Lymphoma, Non-Hodgkin; Methotrexate; Necrosis	1988
Radiation, methotrexate, and white matter necrosis: laboratory evidence for neural radioprotection with preirradiation methotrexate. International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:2 Topics: Animals; Female; Methotrexate; Necrosis; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Spinal Cord	1988
Methotrexate induced skin necrosis in psoriasis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1987, Dec-19, Volume: 72, Issue:12 Topics: Aged; Female; Humans; Methotrexate; Necrosis; Psoriasis; Skin Diseases	1987
Neoadjuvant chemotherapy for high grade osteosarcoma of the extremities: is a good response to preoperative treatment an indication to reduce postoperative chemotherapy? Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Doxorubicin; Extremities; Female; Femoral Neoplasms; Fibula; Humans; Humerus; Infant; Infant, Newborn; Infusions, Intra-Arterial; Injections, Intravenous; Male; Methotrexate; Necrosis; Osteosarcoma; Postoperative Care; Preoperative Care; Tibia; Time Factors	1986
Methotrexate-induced epidermal necrosis. The British journal of dermatology, 1987, Volume: 116, Issue:6 Topics: Aged; Aged, 80 and over; Female; Humans; Methotrexate; Necrosis; Skin	1987
Methotrexate and the liver. The Journal of rheumatology. Supplement, 1985, Volume: 12 Suppl 12 Topics: Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Necrosis; Serum Albumin; Transaminases	1985
Brain stem necrosis after preradiation high-dose methotrexate. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1985, Volume: 1, Issue:6 Topics: Brain Diseases; Brain Neoplasms; Brain Stem; Child, Preschool; Combined Modality Therapy; Female; Humans; Methotrexate; Necrosis; Pineal Gland; Pinealoma; Radiotherapy	1985
Neurologic complications of bone marrow transplantation. Neurology, 1985, Volume: 35, Issue:3 Topics: Adolescent; Adult; Bone Marrow Transplantation; Brain Diseases, Metabolic; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Child; Child, Preschool; Female; Graft vs Host Disease; Humans; Infections; Leukemia; Male; Methotrexate; Middle Aged; Necrosis; Neoplasms; Postoperative Complications; Seizures; Spinal Cord Diseases	1985
Liver biopsy in methotrexate treatment. Acta dermato-venereologica, 1971, Volume: 51, Issue:3 Topics: Adult; Aged; Alanine Transaminase; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Diseases; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Necrosis; Pityriasis; Pityriasis Rubra Pilaris; Psoriasis	1971
Cecal necrosis and perforation with systemic chemotherapy. The American surgeon, 1973, Volume: 39, Issue:3 Topics: Adult; Asparaginase; Breast Neoplasms; Cecal Diseases; Child; Cytarabine; Daunorubicin; Female; Fluorouracil; Humans; Intestinal Perforation; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Necrosis; Prednisone; Thioguanine; Vincristine	1973
Hepatotoxicity of long-term methotrexate therapy for psoriasis. Archives of internal medicine, 1973, Volume: 132, Issue:3 Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Drug Interactions; Ethanol; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Time Factors	1973
Prolonged survival in malignant melanoma of the nose. The Journal of laryngology and otology, 1974, Volume: 88, Issue:1 Topics: Electrocoagulation; Female; Humans; Melanoma; Methotrexate; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Nose Neoplasms; Time Factors	1974
Effects of methotrexate on the liver in psoriasis. The Journal of investigative dermatology, 1974, Volume: 62, Issue:6 Topics: Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Necrosis; Psoriasis; Sulfobromophthalein	1974
Cell proliferation and the differential response of normal and malignant tissues. Silvanus Thompson Memorial Lecture. The British journal of radiology, 1972, Volume: 45, Issue:531 Topics: Animals; Blood Vessels; Busulfan; Cell Survival; Cyclophosphamide; Cytarabine; Diffusion; Epithelial Cells; Epithelium; Fibrosarcoma; Hematopoietic Stem Cells; Intestine, Small; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Mitosis; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Oxygen; Radiation Effects; Rats	1972
Chemotherapy in the treatment of undelivered hydatidiform mole. A study of 5 cases. The Journal of obstetrics and gynaecology of the British Commonwealth, 1971, Volume: 78, Issue:1 Topics: Adult; Female; Gonadotropins; Humans; Hydatidiform Mole; Hysterectomy; Mercaptopurine; Methotrexate; Middle Aged; Necrosis; Pregnancy; Trophoblasts	1971
[Excessive destruction of tissues caused by topical cytotoxic therapy]. Giornale italiano di dermatolotia. Minerva dermatologica, 1970, Volume: 45, Issue:2 Topics: Aged; Benzocycloheptenes; Carcinoma, Basal Cell; Chloroquine; Dermatitis; Facial Neoplasms; Female; Humans; Male; Methotrexate; Middle Aged; Necrosis; Skin Neoplasms; Skin Ulcer	1970
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis. Archives of dermatology, 1970, Volume: 102, Issue:6 Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Sulfobromophthalein	1970