Compounds > methotrexate
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methotrexate and Nasal Polyps

methotrexate has been researched along with Nasal Polyps in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Arici, MA; Cakir Cetin, A; Ecevit, MC; Keskinoglu, P; Onen, F; Tuncok, Y1
Choe, SH; Gu, PM; Heo, KW; Hong, TU; Hur, DY; Lee, YM; Park, SK1
Cho, HW; Heo, KW; Hur, DY; Park, SK1
Aslan, I; Aydin, S; Buyukozturk, S; Colakoglu, B; Dal, M; Gelincik, A1
Asplund, MS; Hagberg, H; Holmström, M1
Balci, G; Başak, T; Cakir, BO; Ercan, I; Ozbal, EA; Sahin, A; Turgut, S1

Trials

1 trial(s) available for methotrexate and Nasal Polyps

ArticleYear
Methotrexate for recurrent chronic rhinosinusitis with nasal polyps: A randomized, controlled, phase 2 clinical trial.
    International forum of allergy & rhinology, 2023, Volume: 13, Issue:9

    Topics: Adrenal Cortex Hormones; Chronic Disease; Humans; Immunoglobulin E; Methotrexate; Nasal Polyps; Rhinitis; Sinusitis; Treatment Outcome

2023

Other Studies

5 other study(ies) available for methotrexate and Nasal Polyps

ArticleYear
Methotrexate Induces Apoptosis in Organ-Cultured Nasal Polyps Via the Fas Pathway.
    The Journal of craniofacial surgery, 2017, Volume: 28, Issue:3

    Topics: Apoptosis; Blotting, Western; Fas Ligand Protein; Gene Expression Regulation; Humans; Immunosuppressive Agents; Methotrexate; Nasal Polyps; Organ Culture Techniques; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2017
Methotrexate induces apoptosis in nasal polyps via caspase cascades and both mitochondria-mediated and p38 mitogen-activated protein kinases/Jun N-terminal kinase pathways.
    American journal of rhinology & allergy, 2013, Volume: 27, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caspases; Cells, Cultured; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Methotrexate; Mitochondria; Nasal Polyps; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Paranasal Sinuses; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2013
Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease?
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2009, Volume: 46, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Female; Forced Expiratory Volume; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nasal Cavity; Nasal Polyps; Paranasal Sinuses; Tomography, X-Ray Computed

2009
Chemotherapy in severe nasal polyposis--a possible beneficial effect? A report of three cases.
    Rhinology, 2010, Volume: 48, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Female; Humans; Male; Methotrexate; Middle Aged; Multiple Myeloma; Nasal Polyps; Remission Induction

2010
Effects of topical application of methotrexate on nasal mucosa in rats: a preclinical assessment study.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006, Volume: 134, Issue:5

    Topics: Administration, Intranasal; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biopsy; Hemoglobins; Immunosuppressive Agents; Liver; Male; Methotrexate; Nasal Mucosa; Nasal Polyps; Rats; Rats, Wistar

2006