methotrexate has been researched along with Mucositis, Oral in 153 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (36.60) | 18.7374 |
| 1990's | 23 (15.03) | 18.2507 |
| 2000's | 26 (16.99) | 29.6817 |
| 2010's | 32 (20.92) | 24.3611 |
| 2020's | 16 (10.46) | 2.80 |
| Authors | Studies |
|---|---|
| Aykac, A; Bilginaylar, K; Özkayalar, H; Sayiner, S; Şehirli, AÖ | 1 |
| Lien, YH; Tsai, HM | 1 |
| Clavarino, A; Gavin, NC; Kennedy, GA; Nakagaki, M; Whitfield, K | 1 |
| Bayramoglu, Z; Bulut, S; Coban, TA; Mammadov, R; Mendil, AS; Mokhtare, B; Suleyman, H; Suleyman, Z | 1 |
| Coêlho, MC; de Oliveira, NFP; de Souza, BF; Persuhn, DC; Valença, AMG; Viana Filho, JMC | 1 |
| Cirillo, N; Huang, J; Hwang, AYM; Iskandar, M; Jia, Y; Kim, B; Mohammed, AI | 1 |
| Suárez, EU; Valencia-Maturana, JC | 1 |
| Abbas, Y; Ali, M; Hussain, M; Kerio, AA; Khan, MA; Khattak, TA | 1 |
| Futatsuki, T; Hikita, H; Imamura, Y; Inada, A; Kashiwazaki, H; Mizutani, S; Mori, Y; Oku, S | 1 |
| Guo, H; Hu, K; Liu, W; Tan, Z; Zhao, R | 1 |
| Clevers, H; de Jonge, R; Driehuis, E; Heil, SG; Jansen, G; Kolders, S; Lin, M; Muller, IB; Oosterom, N; Pieters, R; van den Heuvel-Eibrink, MM | 1 |
| Curra, M; Evangelista, JMC; Ferreira, MBC; Gabriel, AF; Gregianin, L; Martins, MAT; Martins, MD; Roesler, R; Schmidt, TR; Valer, JB | 1 |
| Dahllöf, G; Garming Legert, K; Mattsson, J; Remberger, M; Ringdén, O; Törlén, J | 1 |
| Brunetto, AT; Curra, M; Ferreira, MBC; Gabriel, AF; Gregianin, LJ; Martins, MAT; Martins, MD | 1 |
| Almeida, FLDS; Da Silva, DAC; Deana, AM; Fernandes, KPS; Guimaraes, DM; Junior, JMA; Ota, TMN; Schalch, TD | 1 |
| Chang, YH; Chao, YH; Chiou, YH; Hsu, MC; Peng, CT; Wu, HP; Wu, KH; Yu, MS | 1 |
| de Jonge, R; den Hoed, MAH; García-Orad, A; Gutierrez-Camino, A; Heil, SG; Lopez-Lopez, E; Martin-Guerrero, I; Oosterom, N; Pieters, R; Pluijm, SMF; Tissing, WJE; van den Heuvel-Eibrink, MM | 1 |
| Giavedoni, P; Mascaró, JM; Riquelme-Mc Loughlin, C | 1 |
| de Jonge, R; den Hoed, MAH; Griffioen, PH; Heil, SG; Oosterom, N; Pieters, R; Tissing, WJE; van den Heuvel-Eibrink, MM | 1 |
| Cumpston, KL; Lenczowski, J; Schall, C; Wills, BK | 1 |
| Garrocho-Rangel, JA; Herrera-Moncada, M; Márquez-Preciado, R; Ortiz-Zamudio, JJ; Pozos-Guillén, A; Tejeda-Nava, F | 1 |
| Berrevoets, M; de Jonge, R; den Hoed, MAH; Heil, SG; Hoerning, S; Oosterom, N; Pieters, R; Pluijm, SMF; Tissing, WJE; van den Heuvel-Eibrink, MM; Zolk, O | 1 |
| Lalani, R; Lyu, H; Solomon, DH; Vanni, K | 1 |
| Ganeva, PV; Grklanov, VA; Komitova, RT; Lindas, KK | 1 |
| Heil, SG | 1 |
| de Jonge, R; Heil, SG; Oosterom, N; Pieters, R; van den Heuvel-Eibrink, MM; Van der Beek, JN | 1 |
| Berndt, R; Gassling, V; Kriegelstein, S; Troeltzsch, M; von Blohn, G; Woodlock, T | 1 |
| Langer, T; Möricke, A; Paulides, M; Radtke, S; Renner, B; Schrappe, M; Stanulla, M; Zimmermann, M; Zolk, O | 1 |
| Abreu, EG; Correia, AV; da Cruz Perez, DE; da Mota Vasconcelos Brasil, C; de Castro, JF; de Paula Ramos Pedrosa, F | 1 |
| Cudmore, J; Seftel, M; Sisler, J; Zarychanski, R | 1 |
| Alcocer, S; Bohorquez, D; de Morales, TR; Morón-Medina, A; Viera, N | 1 |
| Goulden, N; Hancock, J; Hough, R; Mitchell, C; Moorman, AV; Rowntree, C; Vora, A; Wade, R | 1 |
| Antin, JH; Carter, SL; Choi, S; Cutler, C; Grupp, S; Hogan, WJ; Horowitz, MM; Hsu, JW; Hu, ZH; Johnston, L; Logan, B; MacMillan, ML; McCarthy, P; Nakamura, R; Pasquini, M; Porter, D; Waller, EK; Wu, J | 1 |
| Biswas, S; Nandakumar, K; Patel, A; Ramalingayya, GV; Shoja, MH | 1 |
| Chan, KK; Chu, MM; Ma, Y; Ngan, HY; Tse, KY | 1 |
| Balcı, YI; Greenwood, T; Kenar, F; Koçyiğit, A; Özgürler Akpınar, F; Polat, A; Tesi, B; Yalçın, N | 1 |
| Bruce, AJ; Chaudhry, HM; Hashmi, SK; Hogan, WJ; Kremers, WK; Litzow, MR; Patnaik, MS; Phillips, GL; Wolf, RC | 1 |
| Endo, T; Fujimoto, K; Goto, H; Hashimoto, D; Hashino, S; Kahata, K; Kashiwazaki, H; Kondo, T; Matsukawa, T; Matsushita, T; Nakazawa, S; Onozawa, M; Sugita, J; Teshima, T; Yamazaki, Y | 1 |
| Ahmad, A; Kazi, MS | 1 |
| Ahmed, AA; El-Sayed, NM; Selim, MA | 1 |
| Chayama, K; Egawa, T; Gomita, Y; Hayashi, Y; Kaji, H; Kitamura, Y; Maiguma, T; Morishima, T; Sendo, T; Teshima, D; Ueshima, S | 1 |
| Kaji, H; Maiguma, T; Makino, K; Teshima, D | 1 |
| Abdulghaffar, EE; Abou El Asrar, M; Adly, AA; El-Bostany, EA; El-Ghouroury, EA; Tantawy, AA | 1 |
| Asaka, M; Endo, T; Fujimoto, K; Hashino, S; Ibata, M; Imamura, M; Kashiwazaki, H; Kondo, T; Kosugi, M; Matsushita, T; Nishio, M; Obara, M; Shigematsu, A; Shiratori, S; Shono, Y; Sugita, J; Takahashi, S; Tanaka, J; Wakasa, K | 1 |
| Arnet, I; Bernhardt, V; Hersberger, KE | 1 |
| Bruggisser, M; Krähenbühl, S; Rätz Bravo, AE | 1 |
| Alvarez, A; Alvarez, CJ; Morales-Rojas, T; Morón-Medina, A; Viera, N | 1 |
| Bardy, P; Diviney, M; Grigg, A; Holdsworth, R; Hoyt, R; King-Kallimanis, B; McCluskey, J; Murphy, NM; Szer, J; Tait, BD | 1 |
| Csóka, M; Csordás, K; Eipel, O; Hegyi, M; Kovács, G; Pap, E | 1 |
| Baptista, AM; Belfort, P | 1 |
| Epstein, JB; Ship, JA; Tsang, AH; Warkentin, D | 1 |
| Cella, D; Fuchs, H; Giles, F; Hurd, D; Martin, PJ; Miller, C; Pulliam, J; Sonis, ST; Wingard, JR | 1 |
| Amouretti, M; Bens, G; Beylot, C; Beylot-Barry, M; Laharie, D; Noblesse, I; Vergier, B | 1 |
| DONOHUE, DM; FOYE, LV; JACOBS, EM; PAPAC, RJ | 1 |
| BEAHRS, OH; CALDAROLA, VT; HARRISON, EG | 1 |
| Blayac, JP; Cociglio, M; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Vallat, C | 1 |
| Araujo, DH; Brito, GA; Carneiro-Filho, BA; Carvalho, GH; Cavalcante, MC; Lima, AA; Lima, IP; Lima, V; Monteiro, SM; Ribeiro, RA; Santos, FN | 1 |
| Campbell, M; Joannon, P; Oviedo, I; Tordecilla, J | 1 |
| Avramis, V; Douglas, JG; Felgenhauer, J; Geyer, JR; Hawkins, DS; Holcenberg, J; Loken, MR; Meshinchi, S; Park, JR; Thomson, B | 1 |
| Babalis, DE; Ganotakis, ES; Mazokopakis, EE; Papadakis, JA; Vrentzos, GE | 1 |
| Alyea, E; Antin, JH; Cutler, C; Harrison, MJ; Ho, V; Hoffmeister, L; Kim, HT; Laglenne, P; Lee, SJ; Li, S; Soiffer, R; Sonis, S; Szeto, KC | 1 |
| Falconer, DT; Kalantzis, A; Marshman, Z; Morgan, PR; Odell, EW | 1 |
| Auersperg, M; Budihna, M; Soba, E; Strojan, P | 1 |
| Kosaki, K; Mori, T; Samejima, H; Sato, R; Shimada, H; Shimasaki, N; Takahashi, T; Tanigawara, Y; Torii, C; Yahagi, N; Yoshihara, H | 1 |
| Brunetto, AL; Castro, CG; Cruz, LB; Rech, A; Ribeiro, AS; Rosa, LG | 1 |
| de Aquino, AR; de Brito Costa, EM; de Souza, LB; Fernandes, MZ; Gordón-Núñez, MA; Pereira Pinto, L; Soares, RC | 1 |
| Alberani, F; Altieri, MC; Arpinati, M; Baccarani, M; Bandini, G; Banfi, M; Barzetti, L; Berni, M; Bonifazi, F; Borrelli, C; Bosi, A; Brignoli, C; Calza, S; Costazza, G; De Vivo, A; Errico, A; Feraut, C; Gori, E; Leanza, S; Loddo, MC; Mega, A; Pirola, E; Polato, E; Sabbi, V | 1 |
| Cheng, KK | 1 |
| Berdel, WE; Bieker, R; Mesters, RM; Müller-Tidow, C; Rudat, A; Schliemann, C; Schmidt, E; Thoennissen, NH; Zühlsdorf, M | 1 |
| Borrie, PF; Mackay, IB; Robinson, TW | 1 |
| Coleman, M; Gordon, B; Hollister, D; Silver, RT | 1 |
| Haustein, B; Helbig, W; Kubel, M; Schultze, W; Schwenke, H; Standke, E; Thierbach, V | 1 |
| Chen, TT; Costanzi, JJ; Livingston, RB; McGavran, M; Mira, JG; Samson, M | 1 |
| Aker, SN; Cheney, CL; Deeg, HJ; Lenssen, P; Moe, GL | 1 |
| Barnwell, R; Berard, CW; Edwards, BK; Jaffe, ES; Janus, C; Magrath, IT; Miliauskas, J; Morris, K; Spiegel, R | 1 |
| Bruckner, HW; Cohen, J | 1 |
| Aboud, A; Blumenschein, GR; Buzdar, AU; Hortobagyi, GN; Yap, HY | 1 |
| Boutseleis, J; Neidhart, JA; Talley, R | 1 |
| Bramwell, V; Buesa, JM; Mouridsen, HT; Santoro, A; Somers, R; Thomas, D; van Oosterom, AT; Vendrik, C; Wagener, T | 1 |
| Babayan, RK; deVere White, R; Krane, RJ; Krikorian, J; Olsson, CA | 1 |
| Anderson, WM; Bleyer, WA; Izutsu, KT; Rice, JC; Schubert, MM; Truelove, EL | 1 |
| Akazawa, S; Furue, H; Hasegawa, K; Kanamaru, R; Niitani, H; Sasaki, T; Taguchi, T; Tominaga, T; Tsukagoshi, S; Yoneda, S | 1 |
| Ramos-Remus, C; Russell, AS; Skeith, KJ | 1 |
| Caporali, R; Montecucco, C; Porta, C; Rossi, S | 1 |
| Colofiore, J; Kemeny, N; Martin, D; Sawyer, R; Schneider, A; Seiter, K; Williams, L | 1 |
| Evans, WE; Liu, Q; Masson, E; Pui, CH; Relling, MV; Sandlund, JT; Schuetz, JD; Synold, TW | 1 |
| Arnold, R; Aul, C; Büchner, T; Diedrich, H; Faak, T; Fabry, U; Fischer, K; Fonatsch, C; Freund, M; Fuhr, HG; Gassmann, W; Gökbuget, N; Gramatzki, M; Heil, G; Heinze, B; Heyll, A; Hiddemann, W; Hoelzer, D; Hossfeld, D; Ittel, TH; Koch, P; Kolbe, K; Kuse, R; Löffler, H; Ludwig, WD; Maschmeyer, G; Messerer, D; Metzner, B; Rieder, H; Schadeck-Gressel, C; Strohscheer, I; Thiel, E; Uberla, K; Völkers, B; Weiss, A | 1 |
| Perez, EA | 1 |
| Bander, JJ; Weinmann, M | 1 |
| Hamuryudan, V; Ince, A; Yazici, H; Yazici, Y | 1 |
| Baume, D; Bladou, F; Camerlo, J; Coulange, C; Cowen, D; Gravis, G; Lechevallier, E; Maraninchi, D; Resbeut, M; Serment, G; Viens, P | 1 |
| Albertioni, F; Peterson, C; Rask, C; Schroeder, H | 1 |
| Blijham, GH | 1 |
| Akaza, H; Kotake, T; Kubota, Y; Matsumura, Y; Miki, T; Togashi, M; Usami, M | 1 |
| Bauer, J; Fartasch, M; Schell, H; Schuler, G | 1 |
| Chen, IH; Chen, JS; Liao, CT; Su, CL; Wang, CH; Wang, HM | 1 |
| Funke, I; Kubanek, B; Platow, S; Wiesneth, M | 1 |
| Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D | 1 |
| Chen, IH; Chen, JS; Liaw, CT; Ng, SH; Wang, CH; Wang, HM; Yang, TS | 1 |
| Ariail, KS; Bigler, J; Farin, FM; Keener, CL; Li, S; Liu, H; Potter, JD; Schubert, MM; Storb, R; Ulrich, CM; Wagner, JL; Yasui, Y | 1 |
| Hamajima, N; Matsuo, K; Morishima, Y; Suzuki, R | 1 |
| Chilcote, RR; Kadin, ME; Kjeldsberg, C; Krailo, MD; Meadows, AT; Morse, M; Siegel, SE; Sposto, R; Steinherz, PG; Termuhlen, AM | 1 |
| Baruchel, A; Bertozzi, AI; Boutard, P; Frappaz, D; Laplanche, A; Mechinaud, F; Michon, J; Nelken, B; Patte, C; Schmitt, C | 1 |
| Kaplan, BH; Moukhtar, M; Vogl, SE | 1 |
| Haas, FD | 1 |
| Nirenberg, A | 1 |
| Moe, PJ; Seip, M | 1 |
| Buechler, M; Chasin, W; Mukherji, B; Nathanson, L | 1 |
| Calabresi, P; Cummings, FJ; Kaplan, HG; Stoller, RG | 1 |
| Bleyer, WA; Oliff, A; Poplack, DG | 1 |
| Bidlingmaier, F; Haas, RJ; Janka, GE; Wiesner, H | 1 |
| Herson, J; Perez, C; Sutow, WW; Wang, YM | 1 |
| Coleman, M; Pasmantier, M; Silver, RT; Turman, S | 1 |
| Hakes, T; Magill, G; Nikrui, M; Ochoa, M | 1 |
| Reiter, D; Ship, II | 1 |
| Edmonson, J; Holland, J; Kazam, E; Krant, M; Olson, K; Schneiderman, M; Scotto, J; Selawry, O; Shnider, B; Taylor, S | 1 |
| Koivisto, V; Oksanen, K; Sinisalo, M; Vikberg, V | 1 |
| McCarthy, GM; Skillings, JR | 1 |
| Amadori, S; Gherlinzoni, F; Guglielmi, C; Mandelli, F; Mazza, P; Tura, S | 1 |
| Benasso, M; Cavallari, M; Corvo, R; Guenzi, M; Margarino, G; Merlano, M; Rosso, R; Scala, M; Sertoli, MR; Siragusa, A | 1 |
| Connors, JM; Hoskins, P; Klimo, P; O'Reilly, SE | 1 |
| Ansari, R; Fisher, WB; Meyer, SC; Roth, BJ; Sledge, GW; Williams, SD | 1 |
| Burns, I; Byrne, M; Gill, G; Harvey, V; Levi, JA; Raghavan, D; Sandeman, T; Snyder, R; Tattersall, M; Thomson, D | 1 |
| Connors, JM; Klimo, P | 1 |
| Eifel, PJ; McClure, S | 1 |
| Arfeen, S; Carey, PJ; Jackson, G; Proctor, SJ; Stark, AN | 1 |
| Glazar, D; Mlakar, U; Modic, M; Pretnar, J | 1 |
| Furst, DE; Kremer, JM | 1 |
| Aarbakke, J; Kolmannskog, S; Moe, PJ; Prytz, PS; Slørdal, L | 1 |
| Dawson, AH; Grygiel, JJ | 1 |
| Polk, JR | 1 |
| Anderson, K; Berenberg, JL; Cooper, RM; Cuttner, J; Faso, L; Terebelo, HR; Wiernik, PH | 1 |
| Balis, FM; Bleyer, WA; Poplack, DG; Reaman, GH; Savitch, JL | 1 |
| Curt, G; Lokich, JJ | 1 |
| Curt, G; Green, R; Lokich, JJ; Paul, S; Phillips, D; Sonneborn, H; Zipoli, TE | 1 |
| Almeyda, J; Levantine, A | 1 |
| Hansen, HH; Holland, JF; McCall, CB; Selawry, OS | 1 |
| Lazar, M; Leopold, IH; Weiner, MJ | 1 |
| Landolt, AM | 1 |
| Foley, JF; Lemon, HM; Miller, D | 1 |
| Cassady, JR; Das, L; Djerassi, I; Farber, S; Frauenberger, G; Geiser, C; Jaffe, N; Kim, BS; Paed, D; Traggis, D | 1 |
| Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Bluestone, R; Bohan, A; Goldberg, LS; Metzger, AL; Pearson, CM | 1 |
| Curran, RE; Johnson, RE; Senyszyn, JJ | 1 |
| Ansfield, FJ; Carter, AC; Goldenberg, IS; Segaloff, A | 1 |
| Weiss, AJ; Wilson, WL | 1 |
| Hausamen, JE | 1 |
| Bodey, GP | 1 |
| Brodthagen, H; Nyfors, A | 1 |
| Beretta, G; Bonadonna, G; De Lena, M; Fossati-Bellani, F; Monfardini, S | 1 |
| Brincker, H | 1 |
| Greither, A | 1 |
9 review(s) available for methotrexate and Mucositis, Oral
| Article | Year |
|---|---|
Experimental Chemotherapy-Induced Mucositis: A Scoping Review Guiding the Design of Suitable Preclinical Models.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Humans; Irinotecan; Methotrexate; Mice; Mucositis; Rabbits; Rats; Reproducibility of Results; Stomatitis; Swine; Zebrafish | 2022 |
The role of genetic polymorphisms in the thymidylate synthase (TYMS) gene in methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia.
Topics: Alleles; Child; Child, Preschool; Female; Gene Expression Regulation; Genetic Association Studies; Genotype; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Tandem Repeat Sequences; Thymidylate Synthase | 2018 |
Low-Dose Methotrexate and Mucocutaneous Adverse Events: Results of a Systematic Literature Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Adult; Aged; Alopecia; Antirheumatic Agents; Double-Blind Method; Female; Folic Acid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Randomized Controlled Trials as Topic; Rheumatic Diseases; Stomatitis | 2020 |
The effect of leucovorin rescue therapy on methotrexate-induced oral mucositis in the treatment of paediatric ALL: A systematic review.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Humans; Infant; Leucovorin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Treatment Outcome; Young Adult | 2019 |
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Methotrexate; Mouth Mucosa; Myeloablative Agonists; Severity of Illness Index; Stomatitis; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2016 |
The role of salivary function in modulating chemotherapy-induced oropharyngeal mucositis: a review of the literature.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Humans; Methotrexate; Mouth Mucosa; Saliva; Stomatitis | 2002 |
Successful treatment with infliximab and methotrexate of pyostomatitis vegetans associated with Crohn's disease.
Topics: Adult; Antibodies, Monoclonal; Crohn Disease; Drug Therapy, Combination; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Mouth Mucosa; Stomatitis; Vulvitis | 2003 |
Oral effects of low-dose methotrexate treatment.
Topics: Aged; Antirheumatic Agents; Bone Marrow; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Female; Folic Acid Antagonists; Gastrointestinal Tract; Humans; Liver; Male; Methotrexate; Middle Aged; Mouth Mucosa; Oral Ulcer; Retrospective Studies; Stomatitis | 2005 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine | 1974 |
33 trial(s) available for methotrexate and Mucositis, Oral
| Article | Year |
|---|---|
Oral mucositis after tacrolimus/sirolimus or cyclosporine/methotrexate as graft-versus-host disease prophylaxis.
Topics: Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Methotrexate; Sirolimus; Stomatitis; Tacrolimus | 2021 |
Low-level laser or LED photobiomodulation on oral mucositis in pediatric patients under high doses of methotrexate: prospective, randomized, controlled trial.
Topics: Child; Humans; Lasers; Low-Level Light Therapy; Methotrexate; Mucositis; Prospective Studies; Stomatitis | 2021 |
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Mucositis; Neoplasm, Residual; Pancreatitis; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Assessment; Stomatitis; Survival Rate; Vincristine | 2014 |
Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT.
Topics: Adolescent; Adult; Allografts; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Sirolimus; Stomatitis; Survival Rate; Tacrolimus; Time Factors | 2014 |
Relationship between oral mucositis and high-dose methotrexate therapy in pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Area Under Curve; Cell Survival; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infant; Keratinocytes; Male; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2008 |
Proinflammatory cytokines during the initial phase of oral mucositis in patients with acute lymphoblastic leukaemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytokines; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Saliva; Stomatitis; Time Factors; Tumor Necrosis Factor-alpha; Young Adult | 2012 |
Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antimicrobial Cationic Peptides; Child; Deglutition Disorders; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Mouth Mucosa; Pain; Pain Measurement; Peptides; Proteins; Severity of Illness Index; Stomatitis; Treatment Outcome | 2003 |
High-dose methotrexate therapy of childhood acute lymphoblastic leukemia: lack of relation between serum methotrexate concentration and creatinine clearance.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chile; Creatine; Disease-Free Survival; Drug Monitoring; Female; Hematologic Diseases; Humans; Infant; Leucovorin; Male; Metabolic Clearance Rate; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2004 |
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteremia; Bone Marrow Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Ifosfamide; Infant; Infusions, Intravenous; Leucovorin; Male; Mesna; Methotrexate; Mouth Mucosa; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis; Thioguanine; Treatment Outcome; Vincristine | 2004 |
Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Child; Child, Preschool; Cohort Studies; Etoposide; Female; Humans; Ifosfamide; Irinotecan; Low-Level Light Therapy; Male; Methotrexate; Mouth Mucosa; Neoplasms; Nutritional Status; Oral Hygiene; Severity of Illness Index; Stomatitis; Treatment Outcome | 2007 |
Cryotherapy in the prevention of oral mucositis in patients receiving low-dose methotrexate following myeloablative allogeneic stem cell transplantation: a prospective randomized study of the Gruppo Italiano Trapianto di Midollo Osseo nurses group.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cryotherapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Stomatitis; Transplantation, Homologous | 2007 |
Combined modality treatment of extensive small cell lung cancer: a Southwest Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Random Allocation; Stomatitis; Vincristine | 1984 |
[The clinical phase I study of TNP-351. The TNP-351 Research Committee].
Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Stomatitis; Vomiting | 1995 |
Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Stomatitis | 1996 |
The frequency and clinical characteristics of methotrexate (MTX) oral toxicity in rheumatoid arthritis (RA): a masked and controlled study.
Topics: Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Single-Blind Method; Stomatitis; Time Factors | 1996 |
Impact of recombinant human granulocyte colony stimulating factor on dose intensity and toxicity of three cycles of methotrexate, vinblastine, doxorubicin and cisplatin in patients with previously untreated urothelial bladder carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neutropenia; Recombinant Proteins; Stomatitis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 1996 |
Monitoring of methotrexate and 7-hydroxymethotrexate in saliva from children with acute lymphoblastic leukemia receiving high-dose consolidation treatment: relation to oral mucositis.
Topics: Child; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Saliva; Stomatitis; Time Factors | 1997 |
The EORTC GI group experience with high-dose infusional 5-FU in colorectal cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Stomatitis; Survival Rate; Treatment Outcome | 1996 |
Effect of recombinant human granulocyte colony stimulating factor (lenograstim) on chemotherapy induced neutropenia in patients with urothelial cancer.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cisplatin; Doxorubicin; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Incidence; Lenograstim; Leukocyte Count; Male; Methotrexate; Middle Aged; Neutropenia; Neutrophils; Recombinant Proteins; Stomatitis; Survival Analysis; Urinary Bladder Neoplasms; Urothelium; Vinblastine | 1999 |
5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Mouth Mucosa; Nausea; Stomatitis; Survival Analysis; Treatment Outcome; Vomiting | 2001 |
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Eruptions; Dyspnea; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Stomatitis; Survival Rate; Treatment Outcome | 2001 |
Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Prednisone; Recurrence; Stomatitis; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine | 2001 |
Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: a randomized study of the French Society of Pediatric Oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Child; Child, Preschool; Cyclophosphamide; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infections; Lymphoma, Non-Hodgkin; Male; Methotrexate; Morbidity; Neutropenia; Prednisone; Stomatitis; Vincristine | 2002 |
High dose methotrexate in acute lymphocytic leukemia in childhood.
Topics: Asparaginase; Child; Clinical Trials as Topic; Dexamethasone; Drug Eruptions; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant; Leucovorin; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Stevens-Johnson Syndrome; Stomatitis; Vincristine | 1978 |
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged; Stomatitis | 1979 |
Methotrexate compared with placebo in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Placebos; Stomatitis | 1977 |
Phase III comparative trial (m-BACOD v m-BNCOD) in the treatment of stage II to IV non-Hodgkin's lymphomas with intermediate- or high-grade histology.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leucovorin; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mitoxantrone; Mouth Mucosa; Neoplasm Staging; Neutropenia; Recurrence; Remission Induction; Stomatitis; Stroke Volume; Survival Rate; Vincristine | 1990 |
Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasm Staging; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
Methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic breast cancer. A phase II trial of the Hoosier Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Evaluation; Female; Hematologic Diseases; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
Prostaglandin E2 in the treatment of oral mucositis due to radiochemotherapy in patients with haematological malignancies.
Topics: Clinical Trials as Topic; Dinoprostone; Humans; Leukemia; Methotrexate; Mouth Mucosa; Stomatitis | 1989 |
Low dosage methotrexate (NSC-740) and cyclophosphamide (NSC 26271) for solid tumors.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Radiography; Rectal Neoplasms; Stomatitis; Wilms Tumor | 1970 |
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.
Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine | 1972 |
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Radiography; Sarcoma, Ewing; Stomatitis; Suppuration; Thrombocytopenia; Vomiting | 1970 |
111 other study(ies) available for methotrexate and Mucositis, Oral
| Article | Year |
|---|---|
Evaluation of the antiapoptotic and anti-inflammatory properties of chitosan in methotrexate-induced oral mucositis in rats.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Methotrexate; Mucositis; Rats; Rats, Wistar; Stomatitis | 2022 |
Stomatitis and Bone Marrow Suppression Followed by Leukoerythroblastosis in a Patient on Long-Term Low-Dose Methotrexate Therapy.
Topics: Bone Marrow; Bone Marrow Diseases; Humans; Methotrexate; Stomatitis | 2022 |
The incidence of severe oral mucositis in patients undergoing different conditioning regimens in haematopoietic stem cell transplantation.
Topics: Cyclophosphamide; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Melphalan; Methotrexate; Retrospective Studies; Stomatitis; Transplantation Conditioning | 2022 |
Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glutathione; Interleukin-1beta; Interleukin-6; Malondialdehyde; Methotrexate; Oxidants; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Saline Solution; Solvents; Stomatitis; Tumor Necrosis Factor-alpha | 2022 |
Polymorphism but not methylation status in the vitamin D receptor gene contributes to oral mucositis in children.
Topics: Adolescent; Adult; Child; Child, Preschool; DNA Methylation; Genetic Predisposition to Disease; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Stomatitis; Young Adult | 2023 |
Pancytopenia and Stomatitis in Two Older Adults.
Topics: Aged; Humans; Methotrexate; Pancytopenia; Stomatitis | 2023 |
Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation.
Topics: Adolescent; Adult; Aged; Child; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Mucositis; Multiple Myeloma; Stomatitis; Transplantation Conditioning; Young Adult | 2023 |
Protective effect of cryotherapy against oral mucositis among allogeneic hematopoietic stem cell transplant recipients using melphalan-based conditioning.
Topics: Cryotherapy; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Methotrexate; Retrospective Studies; Stomatitis; Transplantation Conditioning | 2023 |
Severe toxic effects of low-dose methotrexate treatment for placenta accreta in a patient with methylenetetrahydrofolate reductase mutations.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oral Ulcer; Placenta Accreta; Pregnancy; Severity of Illness Index; Stomatitis | 2020 |
Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Humans; In Vitro Techniques; Leucovorin; Methotrexate; Mouth Mucosa; Organ Culture Techniques; Organoids; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2020 |
Oral mucositis in childhood cancer patients receiving high-dose methotrexate: Prevalence, relationship with other toxicities and methotrexate elimination.
Topics: Antimetabolites, Antineoplastic; Child; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Stomatitis | 2021 |
Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Incidence; Infant; Infant, Newborn; Methotrexate; Risk Factors; Stomatitis | 2021 |
Effectiveness of Parenteral Glutamine on Methotrexate-induced Oral Mucositis in Children with Acute Lymphoblastic Leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Glutamine; Humans; Male; Methotrexate; Parenteral Nutrition; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis | 2017 |
The miR-1206 microRNA variant is associated with methotrexate-induced oral mucositis in pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Gene Frequency; Genetic Association Studies; Humans; Infant; Male; Methotrexate; MicroRNAs; Nucleic Acid Conformation; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Stomatitis | 2017 |
More than skin deep.
Topics: Dermatologic Agents; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer; Stomatitis | 2018 |
Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; DNA Methylation; Female; Humans; Immunophenotyping; Infant; Long Interspersed Nucleotide Elements; Male; Metabolic Networks and Pathways; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylmethionine; Stomatitis | 2018 |
A Woman With Severe Rash.
Topics: Aged; Anti-Bacterial Agents; Exanthema; Febrile Neutropenia; Female; Folic Acid; Humans; Leucovorin; Methotrexate; Necrosis; Pancytopenia; Rheumatic Fever; Skin; Stomatitis | 2018 |
Oral mucositis in paediatric acute lymphoblastic leukemia patients receiving methotrexate-based chemotherapy: case series.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2018 |
Shingles: More than Meets the Eye.
Topics: Arthritis, Rheumatoid; Female; Herpes Zoster; Humans; Methotrexate; Middle Aged; Pancytopenia; Stomatitis | 2019 |
Genetics of high-dose methotrexate-induced oral mucositis: current perspectives.
Topics: Antimetabolites, Antineoplastic; DNA Methylation; Dose-Response Relationship, Drug; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Pharmacogenomic Variants; Stomatitis; Thymidylate Synthase | 2019 |
Oral mucositis in patients receiving low-dose methotrexate therapy for rheumatoid arthritis: report of 2 cases and literature review.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Overdose; Female; Folic Acid; Follow-Up Studies; Gingivitis, Necrotizing Ulcerative; Hospitalization; Humans; Lip Diseases; Methotrexate; Oral Ulcer; Skin Ulcer; Stomatitis; Stomatitis, Herpetic; Tongue Diseases | 2013 |
Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Germ-Line Mutation; Humans; Infant; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Staging; Neoplasm, Residual; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Stomatitis; Survival Rate; Thymidylate Synthase; Tissue Distribution; Treatment Outcome | 2013 |
Low-level laser in prevention and treatment of oral mucositis in pediatric patients with acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Humans; Infant; Low-Level Light Therapy; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Treatment Outcome | 2013 |
Methotrexate and trimethoprim-sulfamethoxazole: toxicity from this combination continues to occur.
Topics: Aged; Anti-Infective Agents; Crohn Disease; Diarrhea; Drug Interactions; Female; Humans; Immunosuppressive Agents; Leucovorin; Methotrexate; Mucositis; Pneumonia, Pneumocystis; Prednisone; Stomatitis; Trimethoprim, Sulfamethoxazole Drug Combination | 2014 |
[Methotrexate as inducer of proinflammatory cytokines by epithelial cells].
Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Laryngeal Neoplasms; Methotrexate; Stomatitis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis.
Topics: Animals; Body Weight; Busulfan; Chromatography, High Pressure Liquid; Disease Models, Animal; Feeding Behavior; Female; Methotrexate; Phytochemicals; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Rats, Wistar; Solanum nigrum; Stomatitis; Survival Analysis; Toxicity Tests, Acute; Water | 2014 |
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Pregnancy; Retrospective Studies; Salvage Therapy; Stomatitis; Survival Rate; Treatment Outcome; Vincristine; Vomiting | 2015 |
A Hemophagocytic Lymphohistiocytosis Case with Newly Defined UNC13D (c.175G>C; p.Ala59Pro) Mutation and a Rare Complication.
Topics: Amino Acid Substitution; Amphotericin B; Aspergillosis; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Debridement; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Humans; Immunocompromised Host; Infant; Lymphohistiocytosis, Hemophagocytic; Membrane Proteins; Methotrexate; Mutation, Missense; Nasal Septal Perforation; Opportunistic Infections; Palate, Soft; Point Mutation; Stomatitis | 2015 |
Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD.
Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Survival; Graft vs Host Disease; Humans; Incidence; Methotrexate; Stomatitis; Tacrolimus; Time Factors | 2016 |
Histological Effect of Methotrexate and Folinic Acid on Oral Epithelium of Albino Rats.
Topics: Animals; Antidotes; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Epithelium; Leucovorin; Methotrexate; Mouth Mucosa; Neoplasms; Random Allocation; Rats; Stomatitis | 2016 |
α-Lipoic acid ameliorates oral mucositis and oxidative stress induced by methotrexate in rats. Histological and immunohistochemical study.
Topics: Animals; Biomarkers; Diarrhea; DNA; Immunohistochemistry; Male; Methotrexate; Mouth Mucosa; Oxidative Stress; Rats; Rats, Wistar; Stomatitis; Thioctic Acid | 2017 |
Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.
Topics: Allopurinol; Amifostine; Antimetabolites, Antineoplastic; Calcium; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Fibroblasts; Fluorouracil; Free Radical Scavengers; Glutamine; Humans; Keratinocytes; Methotrexate; Periodontal Ligament; Protective Agents; Pyrazoles; Reactive Oxygen Species; Stomatitis | 2009 |
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.
Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Stomatitis; Vincristine | 2010 |
Efficacy of folinic acid in preventing oral mucositis in allogeneic hematopoietic stem cell transplant patients receiving MTX as prophylaxis for GVHD.
Topics: Adolescent; Adult; Aged; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Middle Aged; Retrospective Studies; Stomatitis; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2012 |
Methotrexate intoxication: the Pharmaceutical Care process reveals a critical error.
Topics: Administration, Oral; Aged; Community Pharmacy Services; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Medication Errors; Methotrexate; Pharmacists; Professional Role; Psoriasis; Stomatitis | 2012 |
[Severe pancytopenia and stomatitis in a patient treated with low-dose methostraxate].
Topics: Adalimumab; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Biopsy; Bone Marrow; Diagnosis, Differential; Drug Therapy, Combination; Female; Gingivitis, Necrotizing Ulcerative; Humans; Methotrexate; Pancytopenia; Prednisone; Stomatitis | 2011 |
The effect of folinic acid on methylenetetrahydrofolate reductase polymorphisms in methotrexate-treated allogeneic hematopoietic stem cell transplants.
Topics: Antineoplastic Agents; Australia; Cohort Studies; Disease-Free Survival; DNA Mutational Analysis; Female; Genotype; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leucovorin; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Severity of Illness Index; Stomatitis; Transplantation, Homologous | 2012 |
[Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies].
Topics: Adolescent; Antimetabolites, Antineoplastic; Blood Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Drug Administration Schedule; Female; Humans; Kidney; Liver; Liver Failure; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stomatitis; Time Factors; Treatment Outcome | 2011 |
Comparison of methotrexate, actinomycin D, and etoposide for treating low-risk gestational trophoblastic neoplasia.
Topics: Adult; Alopecia; Antineoplastic Agents; Chorionic Gonadotropin; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Nausea; Pregnancy; Prospective Studies; Remission Induction; Stomatitis; Vitamin B Complex; Vomiting; Young Adult | 2012 |
SYSTEMIC THERAPY WITH AMETHOPTERIN IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.
Topics: Bone Marrow Examination; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Humans; Injections, Intravenous; Laryngeal Neoplasms; Leukopenia; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Stomatitis; Tongue Neoplasms; Tonsillar Neoplasms; Toxicology | 1963 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria | 1964 |
Optimal management of methotrexate intoxication in a child with osteosarcoma.
Topics: Acute Kidney Injury; Adolescent; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Mouth Mucosa; Osteosarcoma; Stomatitis | 2004 |
Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenum; Eating; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methotrexate; Potassium; Rats; Rats, Wistar; Sodium; Stomatitis; Water; Weight Loss | 2004 |
Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Flowers; Humans; Immunosuppressive Agents; Matricaria; Methotrexate; Mouthwashes; Phytotherapy; Plant Extracts; Stomatitis | 2005 |
Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens.
Topics: Adult; Cohort Studies; Drug Evaluation; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Length of Stay; Male; Methotrexate; Middle Aged; Mouth Mucosa; Premedication; Retrospective Studies; Sirolimus; Stomatitis; Tacrolimus; Transplantation, Homologous; Treatment Outcome | 2005 |
Radiochemotherapy with Vinblastine, Methotrexate, and Bleomycin in the treatment of verrucous carcinoma of the head and neck.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Verrucous; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage; Remission Induction; Stomatitis; Vinblastine | 2005 |
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.
Topics: Adolescent; Alleles; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genetic Variation; Hematologic Diseases; Humans; Infant; Japan; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis | 2006 |
Prevention of oral lesions in children with acute lymphoblastic leukemia.
Topics: Adolescent; Anti-Infective Agents; Antimetabolites, Antineoplastic; Case-Control Studies; Child; Child, Preschool; Chlorhexidine; Female; Humans; Male; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2006 |
Association of plasma methotrexate, neutropenia, hepatic dysfunction, nausea/vomiting and oral mucositis in children with cancer.
Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Nausea; Neutropenia; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Vomiting | 2008 |
Use of palifermin for the prevention of high-dose methotrexate-induced oral mucositis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibroblast Growth Factor 7; Follow-Up Studies; Humans; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Pain Measurement; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Stomatitis; Treatment Outcome | 2008 |
The treatment of psoriasis with methotrexate.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Alopecia; Anemia, Macrocytic; Aspartate Aminotransferases; Diarrhea; Dyspepsia; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nucleotidases; Psoriasis; Stomatitis; Sulfobromophthalein | 1967 |
Continuous infusion vincristine and bleomycin with high dose methotrexate for resistant non-Hodgkin's lymphoma.
Topics: Adult; Aged; Bleomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Infusions, Parenteral; Leucovorin; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Stomatitis; Time Factors; Vincristine | 1982 |
[Initial results in allo- and auto-bone marrow transplantation in acute leukemia in East Germany].
Topics: Acute Disease; Adolescent; Adult; Body Weight; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cystitis; Cytarabine; Drug Therapy, Combination; Female; Germany, East; Humans; Leukemia; Male; Methotrexate; Mycoses; Stomatitis; Transplantation, Autologous; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 1984 |
Parenteral nutrition in marrow transplant recipients after discharge from the hospital.
Topics: Adolescent; Adult; Age Factors; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporins; Evaluation Studies as Topic; Failure to Thrive; Female; Graft vs Host Disease; Home Nursing; Humans; Interferon Type I; Leukemia; Male; Methotrexate; Middle Aged; Parenteral Nutrition; Stomatitis | 1983 |
An effective therapy for both undifferentiated (including Burkitt's) lymphomas and lymphoblastic lymphomas in children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Burkitt Lymphoma; Child; Child, Preschool; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Staging; Prognosis; Recurrence; Stomatitis; United States | 1984 |
MTX/5-FU trials in gastrointestinal and other cancers.
Topics: Aged; Anemia; Conjunctivitis; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Obstruction; Leucovorin; Methotrexate; Pancytopenia; Probability; Stomatitis | 1983 |
Combination chemotherapy for metastatic breast cancer with fluorouracil, adriamycin, cyclophosphamide, and methotrexate.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Nausea; Neutropenia; Stomatitis; Vomiting | 1984 |
Cis-platinum plus high-dose methotrexate. Toxicity and efficacy in ovarian carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Cisplatin; Cystadenocarcinoma; Drug Therapy, Combination; Female; Humans; Kidney; Leukopenia; Methotrexate; Middle Aged; Ovarian Neoplasms; Stomatitis | 1983 |
Treatment of advanced soft tissue sarcomas with low-dose methotrexate: a phase II trial by the European Organization of Research on Treatment for Cancer (EORTC) Soft Tissue and Bone Sarcoma Group.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Stomatitis | 1984 |
Adjuvant chemotherapy for stage D1 adenocarcinoma of prostate.
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Patient Compliance; Prognosis; Prostatic Neoplasms; Stomatitis; Time Factors | 1983 |
Whole saliva albumin as an indicator of stomatitis in cancer therapy patients.
Topics: Adolescent; Adult; Albumins; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male; Methotrexate; Neoplasms; Radiotherapy; Saliva; Stomatitis | 1981 |
Comparative efficacy and toxicity of 10-ethyl-10-deazaaminopterin and methotrexate in a mycobacterial rat arthritis model.
Topics: Aminopterin; Animals; Arthritis, Experimental; Drug Evaluation, Preclinical; Female; Intestinal Diseases; Methotrexate; Nontuberculous Mycobacteria; Peritonitis; Rats; Rats, Inbred Lew; Stomatitis | 1994 |
Low dose methotrexate therapy--toxic if not taken correctly. Adverse Drug Reactions Advisory Committee.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Australia; Bone Marrow; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Neutropenia; Stomatitis | 1994 |
Allopurinol mouthwashes in methotrexate-induced stomatitis.
Topics: Aged; Allopurinol; Female; Humans; Male; Methotrexate; Middle Aged; Mouthwashes; Stomatitis; Treatment Outcome | 1994 |
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine | 1993 |
Improved outcome in adult B-cell acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Burkitt Lymphoma; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Gastrointestinal Diseases; Humans; Ifosfamide; Leukemic Infiltration; Male; Meninges; Methotrexate; Middle Aged; Prednisone; Remission Induction; Stomatitis; Survival Analysis; Survival Rate; Teniposide; Treatment Outcome; Vincristine | 1996 |
Schedule-dependent edatrexate toxicity.
Topics: Aminopterin; Antineoplastic Agents; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Mucosa; Palliative Care; Stomatitis | 1996 |
Introduction of a new tracheostomy exchange device after percutaneous tracheostomy in a patient with coagulopathy.
Topics: Adult; Blood Coagulation Disorders; Bone Marrow Transplantation; Equipment Design; Humans; Male; Methotrexate; Mouth Mucosa; Respiratory Insufficiency; Stomatitis; Thrombocytopenia; Tracheostomy | 1996 |
[Ulcerative stomatitis as clinical clue to inadvertent methotrexate overdose].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Medication Errors; Methotrexate; Mouth Mucosa; Oral Ulcer; Stomatitis | 1999 |
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oral Submucous Fibrosis; Plants, Medicinal; Stomatitis; Taiwan | 1999 |
Palliative cytoreduction in refractory acute leukemia: a retrospective study of 57 adult patients.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Nausea; Palliative Care; Retrospective Studies; Stomatitis; Thioguanine | 2000 |
Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism.
Topics: Adult; Bilirubin; Biotransformation; Bone Marrow Transplantation; Cohort Studies; Female; Genotype; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mouth Mucosa; Oxidoreductases Acting on CH-NH Group Donors; Platelet Count; Point Mutation; Polymorphism, Genetic; Stomatitis | 2001 |
Attribution of posttransplantation toxicity to methotrexate regarding genotype of methylenetetrahydrofolate reductase gene (MTHFR) polymorphism needs further clarification.
Topics: Genotype; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mouth Mucosa; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Stomatitis | 2001 |
Chemotherapy for advanced cervical cancer with methotrexate, bleomycin, and cis-dichlorodiammineplatinum(II).
Topics: Adult; Aged; Bleomycin; Bone Marrow; Cisplatin; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors; Uterine Cervical Neoplasms | 1979 |
[A patient with Reiter's disease; positive experiences with methotrexate therapy].
Topics: Adult; Arthritis, Reactive; Balanitis; Humans; Keratoderma, Palmoplantar; Keratosis; Male; Methotrexate; Stomatitis | 1976 |
High-dose methotrexate for the patient with osteogenic sarcoma.
Topics: Administration, Oral; Adolescent; Amphotericin B; Anorexia; Blood Platelets; Blood Transfusion; Candidiasis; Drug Eruptions; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Methotrexate; Nausea; Osteosarcoma; Pneumothorax; Stomatitis; Vomiting | 1976 |
A clinical and pharmacological study of high-dose methotrexate with minimal leucovorin rescue.
Topics: Adult; Aged; Bone Marrow; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Infusions, Parenteral; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis | 1979 |
Methotrexate-induced oral mucositis and salivary methotrexate concentrations.
Topics: Humans; Leucovorin; Methotrexate; Mouth Mucosa; Saliva; Stomatitis | 1979 |
[High-dose methotrexate therapy in osteogenic sarcoma: plasma pharmakokinetics to predict toxicity (author's transl)].
Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Creatinine; Humans; Leucovorin; Methotrexate; Osteosarcoma; Radioimmunoassay; Stomatitis | 1979 |
Evaluation of overall toxicity of high-dosage methotrexate regimens.
Topics: Adolescent; Age Factors; Bone Marrow; Bone Neoplasms; Child; Dermatitis; Drug Administration Schedule; Female; Humans; Kidney; Leucovorin; Leukopenia; Liver; Male; Methotrexate; Osteosarcoma; Sex Factors; Stomatitis; Thrombocytopenia; Vincristine | 1979 |
High dose methotrexate with citrovorum factor in adult resistant lymphoma.
Topics: Adolescent; Aged; Antineoplastic Agents; Bone Marrow; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors | 1977 |
Cervix cancer: treatment with combination vincristine and high doses of methotrexate.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors; Uterine Cervical Neoplasms; Vincristine; Vulvar Neoplasms | 1979 |
Stomatitis in patients on anti-neoplastic drugs: report of case and management.
Topics: Agranulocytosis; Breast Neoplasms; Escherichia coli; Female; Humans; Klebsiella Infections; Methotrexate; Middle Aged; Stomatitis | 1976 |
[Vibrio cholerae can be encountered even at home].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Humans; Immunocompromised Host; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Prednisone; Stomatitis; Vibrio cholerae; Vibrio Infections; Vincristine | 1991 |
Orofacial complications of chemotherapy for breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chi-Square Distribution; Cohort Studies; Cyclophosphamide; Facial Pain; Female; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Mouth Mucosa; Peripheral Nervous System Diseases; Prednisone; Prospective Studies; Stomatitis; Surveys and Questionnaires; Vincristine | 1992 |
MACOP-B and VACOP-B in diffuse large cell lymphomas and MOPP/ABV in Hodgkin's disease.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Mucosa; Prednisone; Procarbazine; Prognosis; Remission Induction; Stomatitis; Survival Rate; Vinblastine; Vincristine | 1991 |
Effective salvage chemotherapy with etoposide, dactinomycin, and methotrexate in refractory germ cell cancer. Australasian Germ Cell Trial Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dactinomycin; Drug Evaluation; Etoposide; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Germ Cell and Embryonal; Remission Induction; Stomatitis; Testicular Neoplasms; Time Factors | 1990 |
Minimizing toxicity of MACOP-B.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Prednisone; Stomatitis; Vincristine | 1987 |
Severe chemotherapy-induced recall of radiation mucositis in a patient with non-Hodgkin's lymphoma of Waldeyer's ring.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Prednisone; Radiation Injuries; Recurrence; Stomatitis; Tonsillar Neoplasms; Vincristine | 1989 |
Severe renal toxicity due to intermediate-dose methotrexate.
Topics: Adult; Aged; Back Pain; Bicarbonates; Fluid Therapy; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouthwashes; Sodium; Sodium Bicarbonate; Stomatitis | 1989 |
Methotrexate in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Cell Count; Bone Marrow; Carcinogens; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Drug Eruptions; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Lung Diseases; Methotrexate; Stomatitis; Teratogens | 1988 |
High-dose methotrexate therapy (6-8 g/m2) in childhood malignancies: clinical tolerability and pharmacokinetics.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Half-Life; Humans; Infusions, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Stomatitis; Vincristine | 1987 |
Variability of methotrexate pharmacokinetics and pharmacodynamics.
Topics: Administration, Oral; Arthritis, Rheumatoid; Biological Availability; Bone Marrow; Humans; Liver; Lung; Methotrexate; Stomatitis | 1988 |
Beneficial effects of leucovorin after methotrexate treatment in rheumatoid arthritis: a case report.
Topics: Arthritis, Rheumatoid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stomatitis | 1988 |
Therapy of refractory adult acute lymphoblastic leukemia with vincristine and prednisone plus tandem methotrexate and L-asparaginase. Results of a Cancer and Leukemia Group B Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Female; Hematopoiesis; Humans; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Pneumonia; Prednisone; Stomatitis; Vincristine | 1986 |
Remission induction of meningeal leukemia with high-dose intravenous methotrexate.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions, Parenteral; Leukemia, Lymphoid; Leukocyte Count; Male; Meningeal Neoplasms; Methotrexate; Neutropenia; Seizures; Stomatitis | 1985 |
A phase I and pharmacology study of continuous-infusion low-dose methotrexate administration.
Topics: Adult; Aged; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia | 1985 |
5-Fluorouracil and methotrexate administered simultaneously as a continuous infusion. A phase I study.
Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia | 1985 |
The variability of individual tolerance to methotrexate in cancer patients.
Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting | 1971 |
Treatment of uveitis with methotrexate.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Alopecia; Anti-Bacterial Agents; Child; Chloroquine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Middle Aged; Nausea; Ophthalmia, Sympathetic; Pyrimethamine; Stomatitis; Uveitis; Vision, Ocular; Vomiting | 1969 |
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia | 1971 |
Favorable response of metastatic osteogenic sarcoma to pulse high-dose methotrexate with citrovorum rescue and radiation therapy.
Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Kidney; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiotherapy Dosage; Skin; Stomatitis | 1973 |
Polymyositis and dermatomyositis: combined methotrexate and corticosteroid therapy.
Topics: Adolescent; Adult; Aged; Creatine Kinase; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leg Ulcer; Leukopenia; Liver Function Tests; Lung Diseases; Male; Methotrexate; Middle Aged; Muscles; Myositis; Prednisone; Stomatitis | 1974 |
Phase I study of phenesterin (NSC-104469).
Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Breast Neoplasms; Chlorambucil; Cholestanes; Cyclophosphamide; Estrogens; Fluorouracil; Glucocorticoids; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Secosteroids; Stomatitis; Tachycardia; Thiotepa; Vincristine | 1971 |
Evaluation of the combination of hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in carcinoma of the lung.
Topics: Administration, Oral; Amines; Antineoplastic Agents; Carcinoma, Bronchogenic; Diarrhea; Evaluation Studies as Topic; Humans; Injections, Intramuscular; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Remission, Spontaneous; Stomatitis; Thrombocytopenia; Triazines; Vomiting | 1971 |
[Toxic changes in the mucosa during cytostatic therapy].
Topics: Chemotherapy, Cancer, Regional Perfusion; Humans; Methotrexate; Mouth Mucosa; Mouth Neoplasms; Stomatitis | 1970 |
Oral complications of the myeloproliferative diseases.
Topics: Adolescent; Adult; Aged; Cellulitis; Child; Child, Preschool; Female; Gingival Hypertrophy; Humans; Leukemia; Male; Methotrexate; Middle Aged; Mouth Diseases; Mouth Mucosa; Myeloproliferative Disorders; Oral Hemorrhage; Oral Manifestations; Sepsis; Stomatitis; Tooth Extraction | 1971 |
[Psoriasis. Treatment with methylaminopterin (Methotrexate) in weekly oral doses].
Topics: Adolescent; Adult; Aged; Blood; Chronic Disease; Female; Humans; Male; Methotrexate; Middle Aged; Nausea; Ointments; Psoriasis; Stomatitis; Time Factors | 1969 |
Phase I and preliminary phase II evaluation of adriamycin (NSC 123127).
Topics: Adolescent; Adult; Aged; Alopecia; Anthraquinones; Antibiotics, Antineoplastic; Bone Marrow Diseases; Child; Child, Preschool; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Neoplasms; Prednisolone; Stomatitis; Time Factors; Vincristine | 1970 |
[Combined cytostatic treatment of solid tumours with cyclophosphamide (Endoxan), vincristine, methylaminopterin (Methotrexate) and 5-fluorouracil].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Enteritis; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasms; Neuritis; Remission, Spontaneous; Stomatitis; Vincristine | 1971 |
[The diagnostic importance of mouth mucosa].
Topics: Anti-Bacterial Agents; Diagnosis, Differential; Diagnosis, Oral; Gingivitis; Glossitis; Humans; Hydantoins; Methotrexate; Mouth Diseases; Mouth Mucosa; Stomatitis; Stomatitis, Aphthous | 1968 |