Page last updated: 2024-08-25

methotrexate and Mucositis, Oral

methotrexate has been researched along with Mucositis, Oral in 153 studies

Research

Studies (153)

TimeframeStudies, this research(%)All Research%
pre-199056 (36.60)18.7374
1990's23 (15.03)18.2507
2000's26 (16.99)29.6817
2010's32 (20.92)24.3611
2020's16 (10.46)2.80

Authors

AuthorsStudies
Aykac, A; Bilginaylar, K; Özkayalar, H; Sayiner, S; Şehirli, AÖ1
Lien, YH; Tsai, HM1
Clavarino, A; Gavin, NC; Kennedy, GA; Nakagaki, M; Whitfield, K1
Bayramoglu, Z; Bulut, S; Coban, TA; Mammadov, R; Mendil, AS; Mokhtare, B; Suleyman, H; Suleyman, Z1
Coêlho, MC; de Oliveira, NFP; de Souza, BF; Persuhn, DC; Valença, AMG; Viana Filho, JMC1
Cirillo, N; Huang, J; Hwang, AYM; Iskandar, M; Jia, Y; Kim, B; Mohammed, AI1
Suárez, EU; Valencia-Maturana, JC1
Abbas, Y; Ali, M; Hussain, M; Kerio, AA; Khan, MA; Khattak, TA1
Futatsuki, T; Hikita, H; Imamura, Y; Inada, A; Kashiwazaki, H; Mizutani, S; Mori, Y; Oku, S1
Guo, H; Hu, K; Liu, W; Tan, Z; Zhao, R1
Clevers, H; de Jonge, R; Driehuis, E; Heil, SG; Jansen, G; Kolders, S; Lin, M; Muller, IB; Oosterom, N; Pieters, R; van den Heuvel-Eibrink, MM1
Curra, M; Evangelista, JMC; Ferreira, MBC; Gabriel, AF; Gregianin, L; Martins, MAT; Martins, MD; Roesler, R; Schmidt, TR; Valer, JB1
Dahllöf, G; Garming Legert, K; Mattsson, J; Remberger, M; Ringdén, O; Törlén, J1
Brunetto, AT; Curra, M; Ferreira, MBC; Gabriel, AF; Gregianin, LJ; Martins, MAT; Martins, MD1
Almeida, FLDS; Da Silva, DAC; Deana, AM; Fernandes, KPS; Guimaraes, DM; Junior, JMA; Ota, TMN; Schalch, TD1
Chang, YH; Chao, YH; Chiou, YH; Hsu, MC; Peng, CT; Wu, HP; Wu, KH; Yu, MS1
de Jonge, R; den Hoed, MAH; García-Orad, A; Gutierrez-Camino, A; Heil, SG; Lopez-Lopez, E; Martin-Guerrero, I; Oosterom, N; Pieters, R; Pluijm, SMF; Tissing, WJE; van den Heuvel-Eibrink, MM1
Giavedoni, P; Mascaró, JM; Riquelme-Mc Loughlin, C1
de Jonge, R; den Hoed, MAH; Griffioen, PH; Heil, SG; Oosterom, N; Pieters, R; Tissing, WJE; van den Heuvel-Eibrink, MM1
Cumpston, KL; Lenczowski, J; Schall, C; Wills, BK1
Garrocho-Rangel, JA; Herrera-Moncada, M; Márquez-Preciado, R; Ortiz-Zamudio, JJ; Pozos-Guillén, A; Tejeda-Nava, F1
Berrevoets, M; de Jonge, R; den Hoed, MAH; Heil, SG; Hoerning, S; Oosterom, N; Pieters, R; Pluijm, SMF; Tissing, WJE; van den Heuvel-Eibrink, MM; Zolk, O1
Lalani, R; Lyu, H; Solomon, DH; Vanni, K1
Ganeva, PV; Grklanov, VA; Komitova, RT; Lindas, KK1
Heil, SG1
de Jonge, R; Heil, SG; Oosterom, N; Pieters, R; van den Heuvel-Eibrink, MM; Van der Beek, JN1
Berndt, R; Gassling, V; Kriegelstein, S; Troeltzsch, M; von Blohn, G; Woodlock, T1
Langer, T; Möricke, A; Paulides, M; Radtke, S; Renner, B; Schrappe, M; Stanulla, M; Zimmermann, M; Zolk, O1
Abreu, EG; Correia, AV; da Cruz Perez, DE; da Mota Vasconcelos Brasil, C; de Castro, JF; de Paula Ramos Pedrosa, F1
Cudmore, J; Seftel, M; Sisler, J; Zarychanski, R1
Alcocer, S; Bohorquez, D; de Morales, TR; Morón-Medina, A; Viera, N1
Goulden, N; Hancock, J; Hough, R; Mitchell, C; Moorman, AV; Rowntree, C; Vora, A; Wade, R1
Antin, JH; Carter, SL; Choi, S; Cutler, C; Grupp, S; Hogan, WJ; Horowitz, MM; Hsu, JW; Hu, ZH; Johnston, L; Logan, B; MacMillan, ML; McCarthy, P; Nakamura, R; Pasquini, M; Porter, D; Waller, EK; Wu, J1
Biswas, S; Nandakumar, K; Patel, A; Ramalingayya, GV; Shoja, MH1
Chan, KK; Chu, MM; Ma, Y; Ngan, HY; Tse, KY1
Balcı, YI; Greenwood, T; Kenar, F; Koçyiğit, A; Özgürler Akpınar, F; Polat, A; Tesi, B; Yalçın, N1
Bruce, AJ; Chaudhry, HM; Hashmi, SK; Hogan, WJ; Kremers, WK; Litzow, MR; Patnaik, MS; Phillips, GL; Wolf, RC1
Endo, T; Fujimoto, K; Goto, H; Hashimoto, D; Hashino, S; Kahata, K; Kashiwazaki, H; Kondo, T; Matsukawa, T; Matsushita, T; Nakazawa, S; Onozawa, M; Sugita, J; Teshima, T; Yamazaki, Y1
Ahmad, A; Kazi, MS1
Ahmed, AA; El-Sayed, NM; Selim, MA1
Chayama, K; Egawa, T; Gomita, Y; Hayashi, Y; Kaji, H; Kitamura, Y; Maiguma, T; Morishima, T; Sendo, T; Teshima, D; Ueshima, S1
Kaji, H; Maiguma, T; Makino, K; Teshima, D1
Abdulghaffar, EE; Abou El Asrar, M; Adly, AA; El-Bostany, EA; El-Ghouroury, EA; Tantawy, AA1
Asaka, M; Endo, T; Fujimoto, K; Hashino, S; Ibata, M; Imamura, M; Kashiwazaki, H; Kondo, T; Kosugi, M; Matsushita, T; Nishio, M; Obara, M; Shigematsu, A; Shiratori, S; Shono, Y; Sugita, J; Takahashi, S; Tanaka, J; Wakasa, K1
Arnet, I; Bernhardt, V; Hersberger, KE1
Bruggisser, M; Krähenbühl, S; Rätz Bravo, AE1
Alvarez, A; Alvarez, CJ; Morales-Rojas, T; Morón-Medina, A; Viera, N1
Bardy, P; Diviney, M; Grigg, A; Holdsworth, R; Hoyt, R; King-Kallimanis, B; McCluskey, J; Murphy, NM; Szer, J; Tait, BD1
Csóka, M; Csordás, K; Eipel, O; Hegyi, M; Kovács, G; Pap, E1
Baptista, AM; Belfort, P1
Epstein, JB; Ship, JA; Tsang, AH; Warkentin, D1
Cella, D; Fuchs, H; Giles, F; Hurd, D; Martin, PJ; Miller, C; Pulliam, J; Sonis, ST; Wingard, JR1
Amouretti, M; Bens, G; Beylot, C; Beylot-Barry, M; Laharie, D; Noblesse, I; Vergier, B1
DONOHUE, DM; FOYE, LV; JACOBS, EM; PAPAC, RJ1
BEAHRS, OH; CALDAROLA, VT; HARRISON, EG1
Blayac, JP; Cociglio, M; Hillaire-Buys, D; Margueritte, G; Peyriere, H; Vallat, C1
Araujo, DH; Brito, GA; Carneiro-Filho, BA; Carvalho, GH; Cavalcante, MC; Lima, AA; Lima, IP; Lima, V; Monteiro, SM; Ribeiro, RA; Santos, FN1
Campbell, M; Joannon, P; Oviedo, I; Tordecilla, J1
Avramis, V; Douglas, JG; Felgenhauer, J; Geyer, JR; Hawkins, DS; Holcenberg, J; Loken, MR; Meshinchi, S; Park, JR; Thomson, B1
Babalis, DE; Ganotakis, ES; Mazokopakis, EE; Papadakis, JA; Vrentzos, GE1
Alyea, E; Antin, JH; Cutler, C; Harrison, MJ; Ho, V; Hoffmeister, L; Kim, HT; Laglenne, P; Lee, SJ; Li, S; Soiffer, R; Sonis, S; Szeto, KC1
Falconer, DT; Kalantzis, A; Marshman, Z; Morgan, PR; Odell, EW1
Auersperg, M; Budihna, M; Soba, E; Strojan, P1
Kosaki, K; Mori, T; Samejima, H; Sato, R; Shimada, H; Shimasaki, N; Takahashi, T; Tanigawara, Y; Torii, C; Yahagi, N; Yoshihara, H1
Brunetto, AL; Castro, CG; Cruz, LB; Rech, A; Ribeiro, AS; Rosa, LG1
de Aquino, AR; de Brito Costa, EM; de Souza, LB; Fernandes, MZ; Gordón-Núñez, MA; Pereira Pinto, L; Soares, RC1
Alberani, F; Altieri, MC; Arpinati, M; Baccarani, M; Bandini, G; Banfi, M; Barzetti, L; Berni, M; Bonifazi, F; Borrelli, C; Bosi, A; Brignoli, C; Calza, S; Costazza, G; De Vivo, A; Errico, A; Feraut, C; Gori, E; Leanza, S; Loddo, MC; Mega, A; Pirola, E; Polato, E; Sabbi, V1
Cheng, KK1
Berdel, WE; Bieker, R; Mesters, RM; Müller-Tidow, C; Rudat, A; Schliemann, C; Schmidt, E; Thoennissen, NH; Zühlsdorf, M1
Borrie, PF; Mackay, IB; Robinson, TW1
Coleman, M; Gordon, B; Hollister, D; Silver, RT1
Haustein, B; Helbig, W; Kubel, M; Schultze, W; Schwenke, H; Standke, E; Thierbach, V1
Chen, TT; Costanzi, JJ; Livingston, RB; McGavran, M; Mira, JG; Samson, M1
Aker, SN; Cheney, CL; Deeg, HJ; Lenssen, P; Moe, GL1
Barnwell, R; Berard, CW; Edwards, BK; Jaffe, ES; Janus, C; Magrath, IT; Miliauskas, J; Morris, K; Spiegel, R1
Bruckner, HW; Cohen, J1
Aboud, A; Blumenschein, GR; Buzdar, AU; Hortobagyi, GN; Yap, HY1
Boutseleis, J; Neidhart, JA; Talley, R1
Bramwell, V; Buesa, JM; Mouridsen, HT; Santoro, A; Somers, R; Thomas, D; van Oosterom, AT; Vendrik, C; Wagener, T1
Babayan, RK; deVere White, R; Krane, RJ; Krikorian, J; Olsson, CA1
Anderson, WM; Bleyer, WA; Izutsu, KT; Rice, JC; Schubert, MM; Truelove, EL1
Akazawa, S; Furue, H; Hasegawa, K; Kanamaru, R; Niitani, H; Sasaki, T; Taguchi, T; Tominaga, T; Tsukagoshi, S; Yoneda, S1
Ramos-Remus, C; Russell, AS; Skeith, KJ1
Caporali, R; Montecucco, C; Porta, C; Rossi, S1
Colofiore, J; Kemeny, N; Martin, D; Sawyer, R; Schneider, A; Seiter, K; Williams, L1
Evans, WE; Liu, Q; Masson, E; Pui, CH; Relling, MV; Sandlund, JT; Schuetz, JD; Synold, TW1
Arnold, R; Aul, C; Büchner, T; Diedrich, H; Faak, T; Fabry, U; Fischer, K; Fonatsch, C; Freund, M; Fuhr, HG; Gassmann, W; Gökbuget, N; Gramatzki, M; Heil, G; Heinze, B; Heyll, A; Hiddemann, W; Hoelzer, D; Hossfeld, D; Ittel, TH; Koch, P; Kolbe, K; Kuse, R; Löffler, H; Ludwig, WD; Maschmeyer, G; Messerer, D; Metzner, B; Rieder, H; Schadeck-Gressel, C; Strohscheer, I; Thiel, E; Uberla, K; Völkers, B; Weiss, A1
Perez, EA1
Bander, JJ; Weinmann, M1
Hamuryudan, V; Ince, A; Yazici, H; Yazici, Y1
Baume, D; Bladou, F; Camerlo, J; Coulange, C; Cowen, D; Gravis, G; Lechevallier, E; Maraninchi, D; Resbeut, M; Serment, G; Viens, P1
Albertioni, F; Peterson, C; Rask, C; Schroeder, H1
Blijham, GH1
Akaza, H; Kotake, T; Kubota, Y; Matsumura, Y; Miki, T; Togashi, M; Usami, M1
Bauer, J; Fartasch, M; Schell, H; Schuler, G1
Chen, IH; Chen, JS; Liao, CT; Su, CL; Wang, CH; Wang, HM1
Funke, I; Kubanek, B; Platow, S; Wiesneth, M1
Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D1
Chen, IH; Chen, JS; Liaw, CT; Ng, SH; Wang, CH; Wang, HM; Yang, TS1
Ariail, KS; Bigler, J; Farin, FM; Keener, CL; Li, S; Liu, H; Potter, JD; Schubert, MM; Storb, R; Ulrich, CM; Wagner, JL; Yasui, Y1
Hamajima, N; Matsuo, K; Morishima, Y; Suzuki, R1
Chilcote, RR; Kadin, ME; Kjeldsberg, C; Krailo, MD; Meadows, AT; Morse, M; Siegel, SE; Sposto, R; Steinherz, PG; Termuhlen, AM1
Baruchel, A; Bertozzi, AI; Boutard, P; Frappaz, D; Laplanche, A; Mechinaud, F; Michon, J; Nelken, B; Patte, C; Schmitt, C1
Kaplan, BH; Moukhtar, M; Vogl, SE1
Haas, FD1
Nirenberg, A1
Moe, PJ; Seip, M1
Buechler, M; Chasin, W; Mukherji, B; Nathanson, L1
Calabresi, P; Cummings, FJ; Kaplan, HG; Stoller, RG1
Bleyer, WA; Oliff, A; Poplack, DG1
Bidlingmaier, F; Haas, RJ; Janka, GE; Wiesner, H1
Herson, J; Perez, C; Sutow, WW; Wang, YM1
Coleman, M; Pasmantier, M; Silver, RT; Turman, S1
Hakes, T; Magill, G; Nikrui, M; Ochoa, M1
Reiter, D; Ship, II1
Edmonson, J; Holland, J; Kazam, E; Krant, M; Olson, K; Schneiderman, M; Scotto, J; Selawry, O; Shnider, B; Taylor, S1
Koivisto, V; Oksanen, K; Sinisalo, M; Vikberg, V1
McCarthy, GM; Skillings, JR1
Amadori, S; Gherlinzoni, F; Guglielmi, C; Mandelli, F; Mazza, P; Tura, S1
Benasso, M; Cavallari, M; Corvo, R; Guenzi, M; Margarino, G; Merlano, M; Rosso, R; Scala, M; Sertoli, MR; Siragusa, A1
Connors, JM; Hoskins, P; Klimo, P; O'Reilly, SE1
Ansari, R; Fisher, WB; Meyer, SC; Roth, BJ; Sledge, GW; Williams, SD1
Burns, I; Byrne, M; Gill, G; Harvey, V; Levi, JA; Raghavan, D; Sandeman, T; Snyder, R; Tattersall, M; Thomson, D1
Connors, JM; Klimo, P1
Eifel, PJ; McClure, S1
Arfeen, S; Carey, PJ; Jackson, G; Proctor, SJ; Stark, AN1
Glazar, D; Mlakar, U; Modic, M; Pretnar, J1
Furst, DE; Kremer, JM1
Aarbakke, J; Kolmannskog, S; Moe, PJ; Prytz, PS; Slørdal, L1
Dawson, AH; Grygiel, JJ1
Polk, JR1
Anderson, K; Berenberg, JL; Cooper, RM; Cuttner, J; Faso, L; Terebelo, HR; Wiernik, PH1
Balis, FM; Bleyer, WA; Poplack, DG; Reaman, GH; Savitch, JL1
Curt, G; Lokich, JJ1
Curt, G; Green, R; Lokich, JJ; Paul, S; Phillips, D; Sonneborn, H; Zipoli, TE1
Almeyda, J; Levantine, A1
Hansen, HH; Holland, JF; McCall, CB; Selawry, OS1
Lazar, M; Leopold, IH; Weiner, MJ1
Landolt, AM1
Foley, JF; Lemon, HM; Miller, D1
Cassady, JR; Das, L; Djerassi, I; Farber, S; Frauenberger, G; Geiser, C; Jaffe, N; Kim, BS; Paed, D; Traggis, D1
Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS1
Bluestone, R; Bohan, A; Goldberg, LS; Metzger, AL; Pearson, CM1
Curran, RE; Johnson, RE; Senyszyn, JJ1
Ansfield, FJ; Carter, AC; Goldenberg, IS; Segaloff, A1
Weiss, AJ; Wilson, WL1
Hausamen, JE1
Bodey, GP1
Brodthagen, H; Nyfors, A1
Beretta, G; Bonadonna, G; De Lena, M; Fossati-Bellani, F; Monfardini, S1
Brincker, H1
Greither, A1

Reviews

9 review(s) available for methotrexate and Mucositis, Oral

ArticleYear
Experimental Chemotherapy-Induced Mucositis: A Scoping Review Guiding the Design of Suitable Preclinical Models.
    International journal of molecular sciences, 2022, Dec-06, Volume: 23, Issue:23

    Topics: Animals; Antineoplastic Agents; Fluorouracil; Humans; Irinotecan; Methotrexate; Mice; Mucositis; Rabbits; Rats; Reproducibility of Results; Stomatitis; Swine; Zebrafish

2022
The role of genetic polymorphisms in the thymidylate synthase (TYMS) gene in methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia.
    Pharmacogenetics and genomics, 2018, Volume: 28, Issue:10

    Topics: Alleles; Child; Child, Preschool; Female; Gene Expression Regulation; Genetic Association Studies; Genotype; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Tandem Repeat Sequences; Thymidylate Synthase

2018
Low-Dose Methotrexate and Mucocutaneous Adverse Events: Results of a Systematic Literature Review and Meta-Analysis of Randomized Controlled Trials.
    Arthritis care & research, 2020, Volume: 72, Issue:8

    Topics: Adult; Aged; Alopecia; Antirheumatic Agents; Double-Blind Method; Female; Folic Acid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Randomized Controlled Trials as Topic; Rheumatic Diseases; Stomatitis

2020
The effect of leucovorin rescue therapy on methotrexate-induced oral mucositis in the treatment of paediatric ALL: A systematic review.
    Critical reviews in oncology/hematology, 2019, Volume: 142

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Humans; Infant; Leucovorin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Treatment Outcome; Young Adult

2019
The Incidence and Severity of Oral Mucositis among Allogeneic Hematopoietic Stem Cell Transplantation Patients: A Systematic Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:4

    Topics: Busulfan; Cyclophosphamide; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Methotrexate; Mouth Mucosa; Myeloablative Agonists; Severity of Illness Index; Stomatitis; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2016
The role of salivary function in modulating chemotherapy-induced oropharyngeal mucositis: a review of the literature.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:1

    Topics: Animals; Antineoplastic Agents; Doxorubicin; Humans; Methotrexate; Mouth Mucosa; Saliva; Stomatitis

2002
Successful treatment with infliximab and methotrexate of pyostomatitis vegetans associated with Crohn's disease.
    The British journal of dermatology, 2003, Volume: 149, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Crohn Disease; Drug Therapy, Combination; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Methotrexate; Mouth Mucosa; Stomatitis; Vulvitis

2003
Oral effects of low-dose methotrexate treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2005, Volume: 100, Issue:1

    Topics: Aged; Antirheumatic Agents; Bone Marrow; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Female; Folic Acid Antagonists; Gastrointestinal Tract; Humans; Liver; Male; Methotrexate; Middle Aged; Mouth Mucosa; Oral Ulcer; Retrospective Studies; Stomatitis

2005
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
    The British journal of dermatology, 1974, Volume: 90, Issue:2

    Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine

1974

Trials

33 trial(s) available for methotrexate and Mucositis, Oral

ArticleYear
Oral mucositis after tacrolimus/sirolimus or cyclosporine/methotrexate as graft-versus-host disease prophylaxis.
    Oral diseases, 2021, Volume: 27, Issue:5

    Topics: Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Methotrexate; Sirolimus; Stomatitis; Tacrolimus

2021
Low-level laser or LED photobiomodulation on oral mucositis in pediatric patients under high doses of methotrexate: prospective, randomized, controlled trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:11

    Topics: Child; Humans; Lasers; Low-Level Light Therapy; Methotrexate; Mucositis; Prospective Studies; Stomatitis

2021
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Mucositis; Neoplasm, Residual; Pancreatitis; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Assessment; Stomatitis; Survival Rate; Vincristine

2014
Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT.
    Blood, 2014, Aug-21, Volume: 124, Issue:8

    Topics: Adolescent; Adult; Allografts; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Sirolimus; Stomatitis; Survival Rate; Tacrolimus; Time Factors

2014
Relationship between oral mucositis and high-dose methotrexate therapy in pediatric acute lymphoblastic leukemia.
    International journal of clinical pharmacology and therapeutics, 2008, Volume: 46, Issue:11

    Topics: Adolescent; Antimetabolites, Antineoplastic; Area Under Curve; Cell Survival; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infant; Keratinocytes; Male; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis

2008
Proinflammatory cytokines during the initial phase of oral mucositis in patients with acute lymphoblastic leukaemia.
    International journal of paediatric dentistry, 2012, Volume: 22, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytokines; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Saliva; Stomatitis; Time Factors; Tumor Necrosis Factor-alpha; Young Adult

2012
Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy.
    Cancer, 2003, Jul-15, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antimicrobial Cationic Peptides; Child; Deglutition Disorders; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Mouth Mucosa; Pain; Pain Measurement; Peptides; Proteins; Severity of Illness Index; Stomatitis; Treatment Outcome

2003
High-dose methotrexate therapy of childhood acute lymphoblastic leukemia: lack of relation between serum methotrexate concentration and creatinine clearance.
    Pediatric blood & cancer, 2004, Volume: 43, Issue:1

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chile; Creatine; Disease-Free Survival; Drug Monitoring; Female; Hematologic Diseases; Humans; Infant; Leucovorin; Male; Metabolic Clearance Rate; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis

2004
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
    Pediatric blood & cancer, 2004, Volume: 43, Issue:5

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteremia; Bone Marrow Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Ifosfamide; Infant; Infusions, Intravenous; Leucovorin; Male; Mesna; Methotrexate; Mouth Mucosa; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis; Thioguanine; Treatment Outcome; Vincristine

2004
Influence of low-energy laser in the prevention of oral mucositis in children with cancer receiving chemotherapy.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Child; Child, Preschool; Cohort Studies; Etoposide; Female; Humans; Ifosfamide; Irinotecan; Low-Level Light Therapy; Male; Methotrexate; Mouth Mucosa; Neoplasms; Nutritional Status; Oral Hygiene; Severity of Illness Index; Stomatitis; Treatment Outcome

2007
Cryotherapy in the prevention of oral mucositis in patients receiving low-dose methotrexate following myeloablative allogeneic stem cell transplantation: a prospective randomized study of the Gruppo Italiano Trapianto di Midollo Osseo nurses group.
    Bone marrow transplantation, 2007, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cryotherapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Stomatitis; Transplantation, Homologous

2007
Combined modality treatment of extensive small cell lung cancer: a Southwest Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Random Allocation; Stomatitis; Vincristine

1984
[The clinical phase I study of TNP-351. The TNP-351 Research Committee].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:2

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Drug Administration Schedule; Female; Gastrointestinal Neoplasms; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Methotrexate; Middle Aged; Stomatitis; Vomiting

1995
Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    The Journal of clinical investigation, 1996, Jan-01, Volume: 97, Issue:1

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow; Child; Child, Preschool; Female; Humans; Infant; Male; Methotrexate; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Stomatitis

1996
The frequency and clinical characteristics of methotrexate (MTX) oral toxicity in rheumatoid arthritis (RA): a masked and controlled study.
    Clinical rheumatology, 1996, Volume: 15, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Methotrexate; Middle Aged; Oral Ulcer; Prevalence; Single-Blind Method; Stomatitis; Time Factors

1996
Impact of recombinant human granulocyte colony stimulating factor on dose intensity and toxicity of three cycles of methotrexate, vinblastine, doxorubicin and cisplatin in patients with previously untreated urothelial bladder carcinoma.
    European cytokine network, 1996, Volume: 7, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Infections; Male; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neutropenia; Recombinant Proteins; Stomatitis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine

1996
Monitoring of methotrexate and 7-hydroxymethotrexate in saliva from children with acute lymphoblastic leukemia receiving high-dose consolidation treatment: relation to oral mucositis.
    Anti-cancer drugs, 1997, Volume: 8, Issue:2

    Topics: Child; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Saliva; Stomatitis; Time Factors

1997
The EORTC GI group experience with high-dose infusional 5-FU in colorectal cancer.
    The Journal of infusional chemotherapy, 1996,Summer, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Humans; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Stomatitis; Survival Rate; Treatment Outcome

1996
Effect of recombinant human granulocyte colony stimulating factor (lenograstim) on chemotherapy induced neutropenia in patients with urothelial cancer.
    International journal of urology : official journal of the Japanese Urological Association, 1999, Volume: 6, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cisplatin; Doxorubicin; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Incidence; Lenograstim; Leukocyte Count; Male; Methotrexate; Middle Aged; Neutropenia; Neutrophils; Recombinant Proteins; Stomatitis; Survival Analysis; Urinary Bladder Neoplasms; Urothelium; Vinblastine

1999
5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.
    British journal of cancer, 2001, Apr-20, Volume: 84, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mitomycin; Mouth Mucosa; Nausea; Stomatitis; Survival Analysis; Treatment Outcome; Vomiting

2001
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
    Anti-cancer drugs, 2001, Volume: 12, Issue:4

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Drug Eruptions; Dyspnea; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Recurrence, Local; Radiotherapy, Adjuvant; Stomatitis; Survival Rate; Treatment Outcome

2001
Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group.
    Medical and pediatric oncology, 2001, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Prednisone; Recurrence; Stomatitis; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine

2001
Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: a randomized study of the French Society of Pediatric Oncology.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Child; Child, Preschool; Cyclophosphamide; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infections; Lymphoma, Non-Hodgkin; Male; Methotrexate; Morbidity; Neutropenia; Prednisone; Stomatitis; Vincristine

2002
High dose methotrexate in acute lymphocytic leukemia in childhood.
    Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:3

    Topics: Asparaginase; Child; Clinical Trials as Topic; Dexamethasone; Drug Eruptions; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant; Leucovorin; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Stevens-Johnson Syndrome; Stomatitis; Vincristine

1978
High dose methotrexate with and without BCG therapy in advanced head and neck malignancy.
    Cancer, 1979, Volume: 43, Issue:3

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate; Middle Aged; Stomatitis

1979
Methotrexate compared with placebo in lung cancer.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Placebos; Stomatitis

1977
Phase III comparative trial (m-BACOD v m-BNCOD) in the treatment of stage II to IV non-Hodgkin's lymphomas with intermediate- or high-grade histology.
    Seminars in oncology, 1990, Volume: 17, Issue:6 Suppl 10

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leucovorin; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mitoxantrone; Mouth Mucosa; Neoplasm Staging; Neutropenia; Recurrence; Remission Induction; Stomatitis; Stroke Volume; Survival Rate; Vincristine

1990
Combined chemotherapy and radiation therapy in advanced inoperable squamous cell carcinoma of the head and neck. The final report of a randomized trial.
    Cancer, 1991, Feb-15, Volume: 67, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasm Staging; Radiotherapy Dosage; Remission Induction; Stomatitis; Survival Rate; Vinblastine

1991
Methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic breast cancer. A phase II trial of the Hoosier Oncology Group.
    Cancer, 1991, Jul-15, Volume: 68, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Evaluation; Female; Hematologic Diseases; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Stomatitis; Survival Rate; Vinblastine

1991
Prostaglandin E2 in the treatment of oral mucositis due to radiochemotherapy in patients with haematological malignancies.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Clinical Trials as Topic; Dinoprostone; Humans; Leukemia; Methotrexate; Mouth Mucosa; Stomatitis

1989
Low dosage methotrexate (NSC-740) and cyclophosphamide (NSC 26271) for solid tumors.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:1

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Radiography; Rectal Neoplasms; Stomatitis; Wilms Tumor

1970
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.
    Cancer, 1972, Volume: 30, Issue:2

    Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine

1972
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Radiography; Sarcoma, Ewing; Stomatitis; Suppuration; Thrombocytopenia; Vomiting

1970

Other Studies

111 other study(ies) available for methotrexate and Mucositis, Oral

ArticleYear
Evaluation of the antiapoptotic and anti-inflammatory properties of chitosan in methotrexate-induced oral mucositis in rats.
    Molecular biology reports, 2022, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Methotrexate; Mucositis; Rats; Rats, Wistar; Stomatitis

2022
Stomatitis and Bone Marrow Suppression Followed by Leukoerythroblastosis in a Patient on Long-Term Low-Dose Methotrexate Therapy.
    The American journal of medicine, 2022, Volume: 135, Issue:11

    Topics: Bone Marrow; Bone Marrow Diseases; Humans; Methotrexate; Stomatitis

2022
The incidence of severe oral mucositis in patients undergoing different conditioning regimens in haematopoietic stem cell transplantation.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:11

    Topics: Cyclophosphamide; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Melphalan; Methotrexate; Retrospective Studies; Stomatitis; Transplantation Conditioning

2022
Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation.
    Journal of applied oral science : revista FOB, 2022, Volume: 30

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glutathione; Interleukin-1beta; Interleukin-6; Malondialdehyde; Methotrexate; Oxidants; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Saline Solution; Solvents; Stomatitis; Tumor Necrosis Factor-alpha

2022
Polymorphism but not methylation status in the vitamin D receptor gene contributes to oral mucositis in children.
    Oral diseases, 2023, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Child; Child, Preschool; DNA Methylation; Genetic Predisposition to Disease; Humans; Male; Methotrexate; Polymorphism, Single Nucleotide; Receptors, Calcitriol; Stomatitis; Young Adult

2023
Pancytopenia and Stomatitis in Two Older Adults.
    The American journal of medicine, 2023, Volume: 136, Issue:7

    Topics: Aged; Humans; Methotrexate; Pancytopenia; Stomatitis

2023
Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2023, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Aged; Child; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Mucositis; Multiple Myeloma; Stomatitis; Transplantation Conditioning; Young Adult

2023
Protective effect of cryotherapy against oral mucositis among allogeneic hematopoietic stem cell transplant recipients using melphalan-based conditioning.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023, Aug-15, Volume: 31, Issue:9

    Topics: Cryotherapy; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Methotrexate; Retrospective Studies; Stomatitis; Transplantation Conditioning

2023
Severe toxic effects of low-dose methotrexate treatment for placenta accreta in a patient with methylenetetrahydrofolate reductase mutations.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oral Ulcer; Placenta Accreta; Pregnancy; Severity of Illness Index; Stomatitis

2020
Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Humans; In Vitro Techniques; Leucovorin; Methotrexate; Mouth Mucosa; Organ Culture Techniques; Organoids; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis

2020
Oral mucositis in childhood cancer patients receiving high-dose methotrexate: Prevalence, relationship with other toxicities and methotrexate elimination.
    International journal of paediatric dentistry, 2021, Volume: 31, Issue:2

    Topics: Antimetabolites, Antineoplastic; Child; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Stomatitis

2021
Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:11

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Incidence; Infant; Infant, Newborn; Methotrexate; Risk Factors; Stomatitis

2021
Effectiveness of Parenteral Glutamine on Methotrexate-induced Oral Mucositis in Children with Acute Lymphoblastic Leukemia.
    Nutrition and cancer, 2017, Volume: 69, Issue:5

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Glutamine; Humans; Male; Methotrexate; Parenteral Nutrition; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis

2017
The miR-1206 microRNA variant is associated with methotrexate-induced oral mucositis in pediatric acute lymphoblastic leukemia.
    Pharmacogenetics and genomics, 2017, Volume: 27, Issue:8

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Gene Frequency; Genetic Association Studies; Humans; Infant; Male; Methotrexate; MicroRNAs; Nucleic Acid Conformation; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Stomatitis

2017
More than skin deep.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:9

    Topics: Dermatologic Agents; Female; Humans; Methotrexate; Middle Aged; Psoriasis; Skin Ulcer; Stomatitis

2018
Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia.
    PloS one, 2018, Volume: 13, Issue:7

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; DNA Methylation; Female; Humans; Immunophenotyping; Infant; Long Interspersed Nucleotide Elements; Male; Metabolic Networks and Pathways; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S-Adenosylmethionine; Stomatitis

2018
A Woman With Severe Rash.
    Annals of emergency medicine, 2018, Volume: 72, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Exanthema; Febrile Neutropenia; Female; Folic Acid; Humans; Leucovorin; Methotrexate; Necrosis; Pancytopenia; Rheumatic Fever; Skin; Stomatitis

2018
Oral mucositis in paediatric acute lymphoblastic leukemia patients receiving methotrexate-based chemotherapy: case series.
    European journal of paediatric dentistry, 2018, Volume: 19, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis

2018
Shingles: More than Meets the Eye.
    Folia medica, 2019, Mar-01, Volume: 61, Issue:1

    Topics: Arthritis, Rheumatoid; Female; Herpes Zoster; Humans; Methotrexate; Middle Aged; Pancytopenia; Stomatitis

2019
Genetics of high-dose methotrexate-induced oral mucositis: current perspectives.
    Pharmacogenomics, 2019, Volume: 20, Issue:9

    Topics: Antimetabolites, Antineoplastic; DNA Methylation; Dose-Response Relationship, Drug; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Pharmacogenomic Variants; Stomatitis; Thymidylate Synthase

2019
Oral mucositis in patients receiving low-dose methotrexate therapy for rheumatoid arthritis: report of 2 cases and literature review.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2013, Volume: 115, Issue:5

    Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Overdose; Female; Folic Acid; Follow-Up Studies; Gingivitis, Necrotizing Ulcerative; Hospitalization; Humans; Lip Diseases; Methotrexate; Oral Ulcer; Skin Ulcer; Stomatitis; Stomatitis, Herpetic; Tongue Diseases

2013
Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia.
    Blood, 2013, Jun-27, Volume: 121, Issue:26

    Topics: Adolescent; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Germ-Line Mutation; Humans; Infant; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Staging; Neoplasm, Residual; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Stomatitis; Survival Rate; Thymidylate Synthase; Tissue Distribution; Treatment Outcome

2013
Low-level laser in prevention and treatment of oral mucositis in pediatric patients with acute lymphoblastic leukemia.
    Photomedicine and laser surgery, 2013, Volume: 31, Issue:12

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Humans; Infant; Low-Level Light Therapy; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Treatment Outcome

2013
Methotrexate and trimethoprim-sulfamethoxazole: toxicity from this combination continues to occur.
    Canadian family physician Medecin de famille canadien, 2014, Volume: 60, Issue:1

    Topics: Aged; Anti-Infective Agents; Crohn Disease; Diarrhea; Drug Interactions; Female; Humans; Immunosuppressive Agents; Leucovorin; Methotrexate; Mucositis; Pneumonia, Pneumocystis; Prednisone; Stomatitis; Trimethoprim, Sulfamethoxazole Drug Combination

2014
[Methotrexate as inducer of proinflammatory cytokines by epithelial cells].
    Investigacion clinica, 2014, Volume: 55, Issue:1

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Laryngeal Neoplasms; Methotrexate; Stomatitis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha

2014
Protective effects of aqueous extract of Solanum nigrum Linn. leaves in rat models of oral mucositis.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Animals; Body Weight; Busulfan; Chromatography, High Pressure Liquid; Disease Models, Animal; Feeding Behavior; Female; Methotrexate; Phytochemicals; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Rats, Wistar; Solanum nigrum; Stomatitis; Survival Analysis; Toxicity Tests, Acute; Water

2014
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2015, Volume: 25, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Female; Gestational Trophoblastic Disease; Humans; Hydroxyurea; Methotrexate; Neoplasm Recurrence, Local; Neutropenia; Pregnancy; Retrospective Studies; Salvage Therapy; Stomatitis; Survival Rate; Treatment Outcome; Vincristine; Vomiting

2015
A Hemophagocytic Lymphohistiocytosis Case with Newly Defined UNC13D (c.175G>C; p.Ala59Pro) Mutation and a Rare Complication.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:4

    Topics: Amino Acid Substitution; Amphotericin B; Aspergillosis; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Debridement; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Humans; Immunocompromised Host; Infant; Lymphohistiocytosis, Hemophagocytic; Membrane Proteins; Methotrexate; Mutation, Missense; Nasal Septal Perforation; Opportunistic Infections; Palate, Soft; Point Mutation; Stomatitis

2015
Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD.
    International journal of hematology, 2016, Volume: 104, Issue:1

    Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Survival; Graft vs Host Disease; Humans; Incidence; Methotrexate; Stomatitis; Tacrolimus; Time Factors

2016
Histological Effect of Methotrexate and Folinic Acid on Oral Epithelium of Albino Rats.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016, Volume: 26, Issue:6

    Topics: Animals; Antidotes; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Epithelium; Leucovorin; Methotrexate; Mouth Mucosa; Neoplasms; Random Allocation; Rats; Stomatitis

2016
α-Lipoic acid ameliorates oral mucositis and oxidative stress induced by methotrexate in rats. Histological and immunohistochemical study.
    Life sciences, 2017, Feb-15, Volume: 171

    Topics: Animals; Biomarkers; Diarrhea; DNA; Immunohistochemistry; Male; Methotrexate; Mouth Mucosa; Oxidative Stress; Rats; Rats, Wistar; Stomatitis; Thioctic Acid

2017
Protective effects of amifostine and cyclooxygenase-1 inhibitor against normal human epidermal keratinocyte toxicity induced by methotrexate and 5-fluorouracil.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:1

    Topics: Allopurinol; Amifostine; Antimetabolites, Antineoplastic; Calcium; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Fibroblasts; Fluorouracil; Free Radical Scavengers; Glutamine; Humans; Keratinocytes; Methotrexate; Periodontal Ligament; Protective Agents; Pyrazoles; Reactive Oxygen Species; Stomatitis

2009
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:1

    Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Stomatitis; Vincristine

2010
Efficacy of folinic acid in preventing oral mucositis in allogeneic hematopoietic stem cell transplant patients receiving MTX as prophylaxis for GVHD.
    Bone marrow transplantation, 2012, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leucovorin; Male; Methotrexate; Middle Aged; Retrospective Studies; Stomatitis; Transplantation Conditioning; Transplantation, Homologous; Young Adult

2012
Methotrexate intoxication: the Pharmaceutical Care process reveals a critical error.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:2

    Topics: Administration, Oral; Aged; Community Pharmacy Services; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Medication Errors; Methotrexate; Pharmacists; Professional Role; Psoriasis; Stomatitis

2012
[Severe pancytopenia and stomatitis in a patient treated with low-dose methostraxate].
    Praxis, 2011, Jun-22, Volume: 100, Issue:13

    Topics: Adalimumab; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Biopsy; Bone Marrow; Diagnosis, Differential; Drug Therapy, Combination; Female; Gingivitis, Necrotizing Ulcerative; Humans; Methotrexate; Pancytopenia; Prednisone; Stomatitis

2011
The effect of folinic acid on methylenetetrahydrofolate reductase polymorphisms in methotrexate-treated allogeneic hematopoietic stem cell transplants.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:5

    Topics: Antineoplastic Agents; Australia; Cohort Studies; Disease-Free Survival; DNA Mutational Analysis; Female; Genotype; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leucovorin; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Severity of Illness Index; Stomatitis; Transplantation, Homologous

2012
[Pharmacokinetic analysis of high-dose methotrexate treatments in children with hematologic malignancies].
    Orvosi hetilap, 2011, Oct-02, Volume: 152, Issue:40

    Topics: Adolescent; Antimetabolites, Antineoplastic; Blood Proteins; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Drug Administration Schedule; Female; Humans; Kidney; Liver; Liver Failure; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Stomatitis; Time Factors; Treatment Outcome

2011
Comparison of methotrexate, actinomycin D, and etoposide for treating low-risk gestational trophoblastic neoplasia.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2012, Volume: 119, Issue:1

    Topics: Adult; Alopecia; Antineoplastic Agents; Chorionic Gonadotropin; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leucovorin; Methotrexate; Nausea; Pregnancy; Prospective Studies; Remission Induction; Stomatitis; Vitamin B Complex; Vomiting; Young Adult

2012
SYSTEMIC THERAPY WITH AMETHOPTERIN IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.
    Cancer chemotherapy reports, 1963, Volume: 32

    Topics: Bone Marrow Examination; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Humans; Injections, Intravenous; Laryngeal Neoplasms; Leukopenia; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Stomatitis; Tongue Neoplasms; Tonsillar Neoplasms; Toxicology

1963
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
    JAMA, 1964, Sep-07, Volume: 189

    Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria

1964
Optimal management of methotrexate intoxication in a child with osteosarcoma.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Humans; Male; Methotrexate; Mouth Mucosa; Osteosarcoma; Stomatitis

2004
Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenum; Eating; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Methotrexate; Potassium; Rats; Rats, Wistar; Sodium; Stomatitis; Water; Weight Loss

2004
Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2005, Volume: 12, Issue:1-2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Flowers; Humans; Immunosuppressive Agents; Matricaria; Methotrexate; Mouthwashes; Phytotherapy; Plant Extracts; Stomatitis

2005
Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2005, Volume: 11, Issue:5

    Topics: Adult; Cohort Studies; Drug Evaluation; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Length of Stay; Male; Methotrexate; Middle Aged; Mouth Mucosa; Premedication; Retrospective Studies; Sirolimus; Stomatitis; Tacrolimus; Transplantation, Homologous; Treatment Outcome

2005
Radiochemotherapy with Vinblastine, Methotrexate, and Bleomycin in the treatment of verrucous carcinoma of the head and neck.
    Journal of surgical oncology, 2005, Dec-15, Volume: 92, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Verrucous; Combined Modality Therapy; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Radiotherapy; Radiotherapy Dosage; Remission Induction; Stomatitis; Vinblastine

2005
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:2

    Topics: Adolescent; Alleles; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genetic Variation; Hematologic Diseases; Humans; Infant; Japan; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis

2006
Prevention of oral lesions in children with acute lymphoblastic leukemia.
    International journal of pediatric otorhinolaryngology, 2006, Volume: 70, Issue:11

    Topics: Adolescent; Anti-Infective Agents; Antimetabolites, Antineoplastic; Case-Control Studies; Child; Child, Preschool; Chlorhexidine; Female; Humans; Male; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis

2006
Association of plasma methotrexate, neutropenia, hepatic dysfunction, nausea/vomiting and oral mucositis in children with cancer.
    European journal of cancer care, 2008, Volume: 17, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Chemical and Drug Induced Liver Injury; Child; Epidemiologic Methods; Female; Humans; Male; Methotrexate; Nausea; Neutropenia; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis; Vomiting

2008
Use of palifermin for the prevention of high-dose methotrexate-induced oral mucositis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibroblast Growth Factor 7; Follow-Up Studies; Humans; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Pain Measurement; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Stomatitis; Treatment Outcome

2008
The treatment of psoriasis with methotrexate.
    The British journal of dermatology, 1967, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Alopecia; Anemia, Macrocytic; Aspartate Aminotransferases; Diarrhea; Dyspepsia; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nucleotidases; Psoriasis; Stomatitis; Sulfobromophthalein

1967
Continuous infusion vincristine and bleomycin with high dose methotrexate for resistant non-Hodgkin's lymphoma.
    Cancer, 1982, Nov-01, Volume: 50, Issue:9

    Topics: Adult; Aged; Bleomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Infusions, Parenteral; Leucovorin; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Stomatitis; Time Factors; Vincristine

1982
[Initial results in allo- and auto-bone marrow transplantation in acute leukemia in East Germany].
    Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Body Weight; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cystitis; Cytarabine; Drug Therapy, Combination; Female; Germany, East; Humans; Leukemia; Male; Methotrexate; Mycoses; Stomatitis; Transplantation, Autologous; Transplantation, Homologous; Vincristine; Whole-Body Irradiation

1984
Parenteral nutrition in marrow transplant recipients after discharge from the hospital.
    Experimental hematology, 1983, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Age Factors; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporins; Evaluation Studies as Topic; Failure to Thrive; Female; Graft vs Host Disease; Home Nursing; Humans; Interferon Type I; Leukemia; Male; Methotrexate; Middle Aged; Parenteral Nutrition; Stomatitis

1983
An effective therapy for both undifferentiated (including Burkitt's) lymphomas and lymphoblastic lymphomas in children and young adults.
    Blood, 1984, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Burkitt Lymphoma; Child; Child, Preschool; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Staging; Prognosis; Recurrence; Stomatitis; United States

1984
MTX/5-FU trials in gastrointestinal and other cancers.
    Seminars in oncology, 1983, Volume: 10, Issue:2 Suppl 2

    Topics: Aged; Anemia; Conjunctivitis; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Neoplasms; Humans; Intestinal Obstruction; Leucovorin; Methotrexate; Pancytopenia; Probability; Stomatitis

1983
Combination chemotherapy for metastatic breast cancer with fluorouracil, adriamycin, cyclophosphamide, and methotrexate.
    Journal of surgical oncology, 1984, Volume: 26, Issue:3

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Methotrexate; Nausea; Neutropenia; Stomatitis; Vomiting

1984
Cis-platinum plus high-dose methotrexate. Toxicity and efficacy in ovarian carcinoma.
    American journal of clinical oncology, 1983, Volume: 6, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Cisplatin; Cystadenocarcinoma; Drug Therapy, Combination; Female; Humans; Kidney; Leukopenia; Methotrexate; Middle Aged; Ovarian Neoplasms; Stomatitis

1983
Treatment of advanced soft tissue sarcomas with low-dose methotrexate: a phase II trial by the European Organization of Research on Treatment for Cancer (EORTC) Soft Tissue and Bone Sarcoma Group.
    Cancer treatment reports, 1984, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Stomatitis

1984
Adjuvant chemotherapy for stage D1 adenocarcinoma of prostate.
    Urology, 1983, Volume: 21, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Patient Compliance; Prognosis; Prostatic Neoplasms; Stomatitis; Time Factors

1983
Whole saliva albumin as an indicator of stomatitis in cancer therapy patients.
    Cancer, 1981, Sep-15, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Albumins; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male; Methotrexate; Neoplasms; Radiotherapy; Saliva; Stomatitis

1981
Comparative efficacy and toxicity of 10-ethyl-10-deazaaminopterin and methotrexate in a mycobacterial rat arthritis model.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Aminopterin; Animals; Arthritis, Experimental; Drug Evaluation, Preclinical; Female; Intestinal Diseases; Methotrexate; Nontuberculous Mycobacteria; Peritonitis; Rats; Rats, Inbred Lew; Stomatitis

1994
Low dose methotrexate therapy--toxic if not taken correctly. Adverse Drug Reactions Advisory Committee.
    The Medical journal of Australia, 1994, Jul-18, Volume: 161, Issue:2

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Australia; Bone Marrow; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Neutropenia; Stomatitis

1994
Allopurinol mouthwashes in methotrexate-induced stomatitis.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:5

    Topics: Aged; Allopurinol; Female; Humans; Male; Methotrexate; Middle Aged; Mouthwashes; Stomatitis; Treatment Outcome

1994
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin.
    Cancer, 1993, Mar-01, Volume: 71, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine

1993
Improved outcome in adult B-cell acute lymphoblastic leukemia.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Burkitt Lymphoma; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Gastrointestinal Diseases; Humans; Ifosfamide; Leukemic Infiltration; Male; Meninges; Methotrexate; Middle Aged; Prednisone; Remission Induction; Stomatitis; Survival Analysis; Survival Rate; Teniposide; Treatment Outcome; Vincristine

1996
Schedule-dependent edatrexate toxicity.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Aminopterin; Antineoplastic Agents; Drug Administration Schedule; Head and Neck Neoplasms; Humans; Methotrexate; Mouth Mucosa; Palliative Care; Stomatitis

1996
Introduction of a new tracheostomy exchange device after percutaneous tracheostomy in a patient with coagulopathy.
    The Journal of trauma, 1996, Volume: 40, Issue:2

    Topics: Adult; Blood Coagulation Disorders; Bone Marrow Transplantation; Equipment Design; Humans; Male; Methotrexate; Mouth Mucosa; Respiratory Insufficiency; Stomatitis; Thrombocytopenia; Tracheostomy

1996
[Ulcerative stomatitis as clinical clue to inadvertent methotrexate overdose].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:9

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Medication Errors; Methotrexate; Mouth Mucosa; Oral Ulcer; Stomatitis

1999
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
    American journal of clinical oncology, 1999, Volume: 22, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Oral Submucous Fibrosis; Plants, Medicinal; Stomatitis; Taiwan

1999
Palliative cytoreduction in refractory acute leukemia: a retrospective study of 57 adult patients.
    Annals of hematology, 2000, Volume: 79, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Nausea; Palliative Care; Retrospective Studies; Stomatitis; Thioguanine

2000
Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism.
    Blood, 2001, Jul-01, Volume: 98, Issue:1

    Topics: Adult; Bilirubin; Biotransformation; Bone Marrow Transplantation; Cohort Studies; Female; Genotype; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mouth Mucosa; Oxidoreductases Acting on CH-NH Group Donors; Platelet Count; Point Mutation; Polymorphism, Genetic; Stomatitis

2001
Attribution of posttransplantation toxicity to methotrexate regarding genotype of methylenetetrahydrofolate reductase gene (MTHFR) polymorphism needs further clarification.
    Blood, 2001, Oct-01, Volume: 98, Issue:7

    Topics: Genotype; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mouth Mucosa; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Stomatitis

2001
Chemotherapy for advanced cervical cancer with methotrexate, bleomycin, and cis-dichlorodiammineplatinum(II).
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Adult; Aged; Bleomycin; Bone Marrow; Cisplatin; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors; Uterine Cervical Neoplasms

1979
[A patient with Reiter's disease; positive experiences with methotrexate therapy].
    Nederlands tijdschrift voor geneeskunde, 1976, Apr-03, Volume: 120, Issue:14

    Topics: Adult; Arthritis, Reactive; Balanitis; Humans; Keratoderma, Palmoplantar; Keratosis; Male; Methotrexate; Stomatitis

1976
High-dose methotrexate for the patient with osteogenic sarcoma.
    The American journal of nursing, 1976, Volume: 76, Issue:11

    Topics: Administration, Oral; Adolescent; Amphotericin B; Anorexia; Blood Platelets; Blood Transfusion; Candidiasis; Drug Eruptions; Humans; Infusions, Parenteral; Injections, Intramuscular; Leucovorin; Methotrexate; Nausea; Osteosarcoma; Pneumothorax; Stomatitis; Vomiting

1976
A clinical and pharmacological study of high-dose methotrexate with minimal leucovorin rescue.
    Cancer research, 1979, Volume: 39, Issue:3

    Topics: Adult; Aged; Bone Marrow; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Infusions, Parenteral; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis

1979
Methotrexate-induced oral mucositis and salivary methotrexate concentrations.
    Cancer chemotherapy and pharmacology, 1979, Volume: 2, Issue:3

    Topics: Humans; Leucovorin; Methotrexate; Mouth Mucosa; Saliva; Stomatitis

1979
[High-dose methotrexate therapy in osteogenic sarcoma: plasma pharmakokinetics to predict toxicity (author's transl)].
    Klinische Wochenschrift, 1979, Apr-17, Volume: 57, Issue:8

    Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Creatinine; Humans; Leucovorin; Methotrexate; Osteosarcoma; Radioimmunoassay; Stomatitis

1979
Evaluation of overall toxicity of high-dosage methotrexate regimens.
    Medical and pediatric oncology, 1979, Volume: 6, Issue:3

    Topics: Adolescent; Age Factors; Bone Marrow; Bone Neoplasms; Child; Dermatitis; Drug Administration Schedule; Female; Humans; Kidney; Leucovorin; Leukopenia; Liver; Male; Methotrexate; Osteosarcoma; Sex Factors; Stomatitis; Thrombocytopenia; Vincristine

1979
High dose methotrexate with citrovorum factor in adult resistant lymphoma.
    Cancer, 1977, Volume: 40, Issue:6

    Topics: Adolescent; Aged; Antineoplastic Agents; Bone Marrow; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors

1977
Cervix cancer: treatment with combination vincristine and high doses of methotrexate.
    Cancer, 1979, Volume: 43, Issue:2

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Remission, Spontaneous; Stomatitis; Time Factors; Uterine Cervical Neoplasms; Vincristine; Vulvar Neoplasms

1979
Stomatitis in patients on anti-neoplastic drugs: report of case and management.
    The Bulletin of the Philadelphia County Dental Society, 1976, Volume: 41, Issue:4

    Topics: Agranulocytosis; Breast Neoplasms; Escherichia coli; Female; Humans; Klebsiella Infections; Methotrexate; Middle Aged; Stomatitis

1976
[Vibrio cholerae can be encountered even at home].
    Duodecim; laaketieteellinen aikakauskirja, 1991, Volume: 107, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Humans; Immunocompromised Host; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Prednisone; Stomatitis; Vibrio cholerae; Vibrio Infections; Vincristine

1991
Orofacial complications of chemotherapy for breast cancer.
    Oral surgery, oral medicine, and oral pathology, 1992, Volume: 74, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chi-Square Distribution; Cohort Studies; Cyclophosphamide; Facial Pain; Female; Fluorouracil; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Mouth Mucosa; Peripheral Nervous System Diseases; Prednisone; Prospective Studies; Stomatitis; Surveys and Questionnaires; Vincristine

1992
MACOP-B and VACOP-B in diffuse large cell lymphomas and MOPP/ABV in Hodgkin's disease.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 1

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Mucosa; Prednisone; Procarbazine; Prognosis; Remission Induction; Stomatitis; Survival Rate; Vinblastine; Vincristine

1991
Effective salvage chemotherapy with etoposide, dactinomycin, and methotrexate in refractory germ cell cancer. Australasian Germ Cell Trial Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dactinomycin; Drug Evaluation; Etoposide; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasms, Germ Cell and Embryonal; Remission Induction; Stomatitis; Testicular Neoplasms; Time Factors

1990
Minimizing toxicity of MACOP-B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Methotrexate; Prednisone; Stomatitis; Vincristine

1987
Severe chemotherapy-induced recall of radiation mucositis in a patient with non-Hodgkin's lymphoma of Waldeyer's ring.
    International journal of radiation oncology, biology, physics, 1989, Volume: 17, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Prednisone; Radiation Injuries; Recurrence; Stomatitis; Tonsillar Neoplasms; Vincristine

1989
Severe renal toxicity due to intermediate-dose methotrexate.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:4

    Topics: Adult; Aged; Back Pain; Bicarbonates; Fluid Therapy; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouthwashes; Sodium; Sodium Bicarbonate; Stomatitis

1989
Methotrexate in rheumatoid arthritis.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:3

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Cell Count; Bone Marrow; Carcinogens; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Drug Eruptions; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Lung Diseases; Methotrexate; Stomatitis; Teratogens

1988
High-dose methotrexate therapy (6-8 g/m2) in childhood malignancies: clinical tolerability and pharmacokinetics.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Half-Life; Humans; Infusions, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Stomatitis; Vincristine

1987
Variability of methotrexate pharmacokinetics and pharmacodynamics.
    Agents and actions. Supplements, 1988, Volume: 24

    Topics: Administration, Oral; Arthritis, Rheumatoid; Biological Availability; Bone Marrow; Humans; Liver; Lung; Methotrexate; Stomatitis

1988
Beneficial effects of leucovorin after methotrexate treatment in rheumatoid arthritis: a case report.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:12

    Topics: Arthritis, Rheumatoid; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Stomatitis

1988
Therapy of refractory adult acute lymphoblastic leukemia with vincristine and prednisone plus tandem methotrexate and L-asparaginase. Results of a Cancer and Leukemia Group B Study.
    American journal of clinical oncology, 1986, Volume: 9, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Female; Hematopoiesis; Humans; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Pneumonia; Prednisone; Stomatitis; Vincristine

1986
Remission induction of meningeal leukemia with high-dose intravenous methotrexate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:4

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions, Parenteral; Leukemia, Lymphoid; Leukocyte Count; Male; Meningeal Neoplasms; Methotrexate; Neutropenia; Seizures; Stomatitis

1985
A phase I and pharmacology study of continuous-infusion low-dose methotrexate administration.
    Cancer, 1985, Nov-15, Volume: 56, Issue:10

    Topics: Adult; Aged; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia

1985
5-Fluorouracil and methotrexate administered simultaneously as a continuous infusion. A phase I study.
    Cancer, 1985, Nov-15, Volume: 56, Issue:10

    Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Neoplasms; Stomatitis; Thrombocytopenia

1985
The variability of individual tolerance to methotrexate in cancer patients.
    British journal of cancer, 1971, Volume: 25, Issue:2

    Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting

1971
Treatment of uveitis with methotrexate.
    American journal of ophthalmology, 1969, Volume: 67, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Alopecia; Anti-Bacterial Agents; Child; Chloroquine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Middle Aged; Nausea; Ophthalmia, Sympathetic; Pyrimethamine; Stomatitis; Uveitis; Vision, Ocular; Vomiting

1969
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
    Acta neurochirurgica, 1971, Volume: 24, Issue:4

    Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia

1971
Favorable response of metastatic osteogenic sarcoma to pulse high-dose methotrexate with citrovorum rescue and radiation therapy.
    Cancer, 1973, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Bone Marrow; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Kidney; Leucovorin; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma; Radiotherapy Dosage; Skin; Stomatitis

1973
Polymyositis and dermatomyositis: combined methotrexate and corticosteroid therapy.
    Annals of internal medicine, 1974, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Aged; Creatine Kinase; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leg Ulcer; Leukopenia; Liver Function Tests; Lung Diseases; Male; Methotrexate; Middle Aged; Muscles; Myositis; Prednisone; Stomatitis

1974
Phase I study of phenesterin (NSC-104469).
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Breast Neoplasms; Chlorambucil; Cholestanes; Cyclophosphamide; Estrogens; Fluorouracil; Glucocorticoids; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Secosteroids; Stomatitis; Tachycardia; Thiotepa; Vincristine

1971
Evaluation of the combination of hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in carcinoma of the lung.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Administration, Oral; Amines; Antineoplastic Agents; Carcinoma, Bronchogenic; Diarrhea; Evaluation Studies as Topic; Humans; Injections, Intramuscular; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Remission, Spontaneous; Stomatitis; Thrombocytopenia; Triazines; Vomiting

1971
[Toxic changes in the mucosa during cytostatic therapy].
    Deutsche zahnarztliche Zeitschrift, 1970, Volume: 25, Issue:10

    Topics: Chemotherapy, Cancer, Regional Perfusion; Humans; Methotrexate; Mouth Mucosa; Mouth Neoplasms; Stomatitis

1970
Oral complications of the myeloproliferative diseases.
    Postgraduate medicine, 1971, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Aged; Cellulitis; Child; Child, Preschool; Female; Gingival Hypertrophy; Humans; Leukemia; Male; Methotrexate; Middle Aged; Mouth Diseases; Mouth Mucosa; Myeloproliferative Disorders; Oral Hemorrhage; Oral Manifestations; Sepsis; Stomatitis; Tooth Extraction

1971
[Psoriasis. Treatment with methylaminopterin (Methotrexate) in weekly oral doses].
    Ugeskrift for laeger, 1969, Aug-21, Volume: 131, Issue:34

    Topics: Adolescent; Adult; Aged; Blood; Chronic Disease; Female; Humans; Male; Methotrexate; Middle Aged; Nausea; Ointments; Psoriasis; Stomatitis; Time Factors

1969
Phase I and preliminary phase II evaluation of adriamycin (NSC 123127).
    Cancer research, 1970, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Aged; Alopecia; Anthraquinones; Antibiotics, Antineoplastic; Bone Marrow Diseases; Child; Child, Preschool; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Neoplasms; Prednisolone; Stomatitis; Time Factors; Vincristine

1970
[Combined cytostatic treatment of solid tumours with cyclophosphamide (Endoxan), vincristine, methylaminopterin (Methotrexate) and 5-fluorouracil].
    Ugeskrift for laeger, 1971, May-14, Volume: 133, Issue:19

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Enteritis; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasms; Neuritis; Remission, Spontaneous; Stomatitis; Vincristine

1971
[The diagnostic importance of mouth mucosa].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1968, Volume: 23, Issue:5

    Topics: Anti-Bacterial Agents; Diagnosis, Differential; Diagnosis, Oral; Gingivitis; Glossitis; Humans; Hydantoins; Methotrexate; Mouth Diseases; Mouth Mucosa; Stomatitis; Stomatitis, Aphthous

1968