Page last updated: 2024-08-25

methotrexate and Metabolic Syndrome

methotrexate has been researched along with Metabolic Syndrome in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (10.34)29.6817
2010's22 (75.86)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Beburov, MY; Brovkin, AN; Dyachenko, IA; Frolova, AA; Goryacheva, NA; Kaluzhsky, VE; Kazakov, VA; Murashev, AN; Pakhomova, IA; Rasskazova, EA; Sadovnikova, ES; Shaykhutdinova, ER; Slashcheva, GA; Tukhovskaya, EA1
Chonprasertsuk, S; Jatuworapruk, K; Lertnawapan, R; Siramolpiwat, S1
Armstrong, AW; Connor, C; Cordoro, KM; Davis, DMR; Elewski, BE; Elmets, CA; Farley Prater, EA; Gelfand, JM; Gordon, KB; Gottlieb, AB; Hariharan, V; Kaplan, DH; Kavanaugh, A; Kiselica, M; Kivelevitch, D; Korman, NJ; Kroshinsky, D; Lebwohl, M; Leonardi, CL; Lichten, J; Lim, HW; Mehta, NN; Menter, A; Paller, AS; Parra, SL; Pathy, AL; Rupani, RN; Siegel, M; Stoff, B; Strober, BE; Wong, EB; Wu, JJ1
Bellinato, F; Bruni, M; De Angelis, G; Girolomoni, G; Gisondi, P1
Alazawi, W; Cho, W; Shetty, A; Syn, WK1
Fassio, A; Gatti, D; Giollo, A; Girolomoni, G; Gisondi, P; Idolazzi, L; Rossini, M; Viapiana, O; Zamboni, M1
Bertrand, O; Butman, S; Clearfield, M; Everett, BM; Glynn, RJ; Goldhaber, SZ; Gupta, M; Hasan, A; Iturriaga, E; Johnston, J; Le May, M; Libby, P; MacFadyen, JG; Mam, V; Ofori, C; Paynter, NP; Pradhan, A; Ridker, PM; Rosenberg, Y; Saklayen, M; Seagle, R; Singh, N; Solomon, DH; Tsigoulis, M; Verma, S; Zaharris, E1
Chonprasertsuk, S; Lertnawapan, R; Siramolpiwat, S1
Abdelli, N; Ben Lagha, I; Dhaoui, MR; Jaber, K; Mrabet, A; Rabhi, F; Slimane, BB1
Clearfield, M; Everett, BM; Glynn, RJ; Gupta, M; Hasan, AA; Libby, P; Macfadyen, J; Paynter, N; Pradhan, AD; Ridker, PM; Solomon, DH; Zaharris, E1
Calhau, C; Cunha, A; Faria, A; Keating, E; Marques, C; Meireles, M; Monteiro, R; Pestana, D; Teixeira, D1
Atteno, M; Caso, F; Caso, P; Costa, L; Darda, MA; Del Puente, A; Fiocco, U; Ortolan, A; Punzi, L; Ramonda, R; Scarpa, R1
Pais, R; Ratziu, V; Rusu, E1
Abourazzak, FE; Harzy, T; Mansouri, S; Najdi, A; Nejjari, C; Tahiri, L1
Aithal, GP; Dawwas, MF1
Kirby, B; Ryan, C1
Philipsen, P; Skiveren, J; Therming, G1
Biterman, H; Cohen, AD; Feldhamer, I; Freud, T; Greenberg-Dotan, S; Harman-Boehm, I; Moser, H; Polishchuk, I; Shalom, G; Zisman, D1
Mahmud, TH; Rasheed, A; Wagan, AA; Zafar, ZA1
KaliƄska-Bienias, A; Kowalewski, C; Lesniewska, A; Schwartz, R; Wozniak, K1
Berman, E; Cohen, AD; Eran, CB; Feldhamer, I; Freud, T; Hodak, E; Oren, S; Pavlovsky, L; Shalom, G; Ziv, M1
Douglas, KM; John, H; Kitas, GD; Panoulas, VF; Toms, TE1
Dijkmans, BA; Nurmohamed, MT; Raterman, HG; Voskuyl, AE1
Ferrazzi, A; Girolomoni, G; Gisondi, P1
Akhlaghi, S; Ferns, GA; Ghayour-Mobarhan, M; Goshayeshi, L; Hatef, MR; Mirfeizi, Z; Rezaieyazdi, Z; Sahebari, M; Sahebkar, A1
Kikuchi, N; Kuhara, M; Saiki, O; Shiraishi, S; Uda, H1
Menter, A; Ryan, C1
Larrain, S; Rinella, ME1
Beutner, KR; Bhushan, R; Elmets, CA; Feldman, SR; Gordon, KB; Gottlieb, A; Koo, JY; Korman, NJ; Lebwohl, M; Leonardi, CL; Menter, A; Van Voorhees, AS1

Reviews

6 review(s) available for methotrexate and Metabolic Syndrome

ArticleYear
Methotrexate Hepatotoxicity and the Impact of Nonalcoholic Fatty Liver Disease.
    The American journal of the medical sciences, 2017, Volume: 354, Issue:2

    Topics: Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Diabetes Mellitus; Humans; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Risk Factors

2017
The impact of obesity and metabolic syndrome on chronic hepatitis B and drug-induced liver disease.
    Clinics in liver disease, 2014, Volume: 18, Issue:1

    Topics: Acetaminophen; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Insulin Resistance; Male; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Prevalence; Risk Factors; Trans-Activators; Viral Regulatory and Accessory Proteins

2014
Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities.
    Dermatologic clinics, 2015, Volume: 33, Issue:1

    Topics: Acitretin; Adipokines; Alcoholism; Antibodies, Monoclonal, Humanized; Cardiovascular Diseases; Comorbidity; Cyclosporine; Dermatologic Agents; Diabetes Mellitus; Fumarates; Humans; Immunosuppressive Agents; Inflammation; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; Risk Factors; Smoking; Tumor Necrosis Factor-alpha; Ustekinumab

2015
Metabolic comorbidities and psoriasis.
    Acta dermatovenerologica Croatica : ADC, 2010, Volume: 18, Issue:4

    Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Dyslipidemias; Fatty Liver; Humans; Hypertriglyceridemia; Immunosuppressive Agents; Insulin Resistance; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Psoriasis; Risk Factors

2010
Psoriasis and cardiovascular disorders.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2012, Volume: 147, Issue:2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Cardiotonic Agents; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus; Humans; Inflammation; Interleukin-12 Subunit p40; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Smoking; Tumor Necrosis Factor-alpha; Ustekinumab

2012
A myriad of pathways to NASH.
    Clinics in liver disease, 2012, Volume: 16, Issue:3

    Topics: Amiodarone; Anti-Retroviral Agents; Bacterial Infections; Cannabis; Diet; Fatty Liver; Genetic Diseases, Inborn; Glucocorticoids; Humans; Hypothyroidism; Insulin Resistance; Intestinal Diseases; Lipid Metabolism; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Occupational Diseases; Perhexiline

2012

Trials

3 trial(s) available for methotrexate and Metabolic Syndrome

ArticleYear
Methotrexate vs secukinumab safety in psoriasis patients with metabolic syndrome.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Female; Humans; Male; Metabolic Syndrome; Methotrexate; Psoriasis; Severity of Illness Index; Treatment Outcome

2020
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events.
    The New England journal of medicine, 2019, 02-21, Volume: 380, Issue:8

    Topics: Aged; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Confidence Intervals; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Statistics, Nonparametric; Stroke; Transaminases

2019
Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis.
    American heart journal, 2013, Volume: 166, Issue:2

    Topics: Algorithms; Anti-Inflammatory Agents; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Inflammation; Metabolic Syndrome; Methotrexate; Myocardial Infarction; Research Design

2013

Other Studies

20 other study(ies) available for methotrexate and Metabolic Syndrome

ArticleYear
AICAR Improves Outcomes of Metabolic Syndrome and Type 2 Diabetes Induced by High-Fat Diet in C57Bl/6 Male Mice.
    International journal of molecular sciences, 2022, Dec-11, Volume: 23, Issue:24

    Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Male; Metabolic Syndrome; Methotrexate; Mice; Mice, Inbred C57BL; Ribonucleosides

2022
Correlation between Cumulative Methotrexate Dose, Metabolic Syndrome and Hepatic Fibrosis Detected by FibroScan in Rheumatoid Arthritis Patients.
    Medicina (Kaunas, Lithuania), 2023, May-26, Volume: 59, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Elasticity Imaging Techniques; Humans; Insulin Resistance; Liver Cirrhosis; Metabolic Syndrome; Methotrexate

2023
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients.
    Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Anthralin; Biological Products; Calcineurin Inhibitors; Cardiovascular Diseases; Child; Child, Preschool; Coal Tar; Comorbidity; Cyclosporine; Dermatologic Agents; Dyslipidemias; Evidence-Based Medicine; Humans; Infant; Infant, Newborn; Inflammatory Bowel Diseases; Insulin Resistance; Mental Health; Metabolic Syndrome; Methotrexate; Nicotinic Acids; Obesity; Photochemotherapy; Psoriasis; Retinoids

2020
Effects of secukinumab on serum adipocytokines: preliminary data.
    Reumatismo, 2017, Sep-21, Volume: 69, Issue:3

    Topics: Adipokines; Adipose Tissue, White; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Drug Therapy, Combination; Female; Humans; Interleukin-17; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prospective Studies; Sex Factors

2017
Association between cumulative methotrexate dose, non-invasive scoring system and hepatic fibrosis detected by Fibroscan in rheumatoid arthritis patients receiving methotrexate.
    International journal of rheumatic diseases, 2019, Volume: 22, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Fatty Liver; Female; Humans; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2019
Psoriasis and liver fibrosis: an investigation using transient elastography in Tunisian patients with psoriasis.
    The British journal of dermatology, 2019, Volume: 181, Issue:6

    Topics: Adult; Comorbidity; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Female; Humans; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prevalence; Psoriasis; Severity of Illness Index; Tunisia

2019
Methotrexate enhances 3T3-L1 adipocytes hypertrophy.
    Cell biology and toxicology, 2013, Volume: 29, Issue:4

    Topics: 3T3 Cells; Adipocytes; Adipogenesis; Animals; Arthritis, Rheumatoid; Biological Transport; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Folic Acid Antagonists; Glucose; Insulin; Lipid Metabolism; Metabolic Syndrome; Methotrexate; Mice; Obesity

2013
Impact of 24-month treatment with etanercept, adalimumab, or methotrexate on metabolic syndrome components in a cohort of 210 psoriatic arthritis patients.
    Clinical rheumatology, 2014, Volume: 33, Issue:6

    Topics: Adalimumab; Adipocytes; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Apoptosis; Arthritis, Psoriatic; Biological Products; Cohort Studies; Comorbidity; Etanercept; Female; Humans; Immunoglobulin G; Inflammation; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha

2014
Prevalence of metabolic syndrome in patients with rheumatoid arthritis in Morocco: a cross-sectional study of 179 cases.
    Clinical rheumatology, 2014, Volume: 33, Issue:11

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Morocco; Prevalence; Risk Factors

2014
End-stage methotrexate-related liver disease is rare and associated with features of the metabolic syndrome.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:8

    Topics: Aged; Body Mass Index; Cholangitis, Sclerosing; Diabetes Mellitus; End Stage Liver Disease; Female; Humans; Immunosuppressive Agents; Liver Diseases, Alcoholic; Liver Transplantation; Logistic Models; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Non-alcoholic Fatty Liver Disease; Odds Ratio; Risk Factors; United States

2014
Patients with psoriasis have insufficient knowledge of their risk of atherothrombotic disease and metabolic syndrome.
    Clinical and experimental dermatology, 2015, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Psoriatic; Atherosclerosis; Depressive Disorder; Diabetes Mellitus; Female; Health Knowledge, Attitudes, Practice; Humans; Hypertension; Immunosuppressive Agents; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Obesity; Patient Education as Topic; Psoriasis; Risk Factors; Thrombosis; Young Adult

2015
Factors associated with drug survival of methotrexate and acitretin in patients with psoriasis.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:8

    Topics: Acitretin; Administration, Oral; Adult; Age Factors; Aged; Arthritis, Psoriatic; Databases, Factual; Dermatologic Agents; Drug Prescriptions; Female; Folic Acid; Humans; Israel; Kaplan-Meier Estimate; Keratolytic Agents; Male; Medication Adherence; Metabolic Syndrome; Methotrexate; Middle Aged; Psoriasis

2015
Frequency of metabolic syndrome in Pakistani cohort of patients with rheumatoid arthritis.
    JPMA. The Journal of the Pakistan Medical Association, 2016, Volume: 66, Issue:6

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Pakistan; Young Adult

2016
Development of bullous pemphigoid in a patient with psoriasis and metabolic syndrome.
    Cutis, 2016, Volume: 98, Issue:3

    Topics: Adult; Autoantibodies; Dose-Response Relationship, Drug; Dystonin; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Metabolic Syndrome; Methotrexate; Pemphigoid, Bullous; Psoriasis; Treatment Outcome

2016
Biologic drug survival in Israeli psoriasis patients.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Acitretin; Adalimumab; Adult; Databases, Factual; Dermatologic Agents; Drug Substitution; Drug Therapy, Combination; Drug Tolerance; Etanercept; Female; Humans; Immunosuppressive Agents; Infliximab; Interleukin-12 Receptor beta 1 Subunit; Israel; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Psoriasis; Time Factors; Tumor Necrosis Factor-alpha; Ustekinumab

2017
Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study.
    Arthritis research & therapy, 2009, Volume: 11, Issue:4

    Topics: Adult; Age Factors; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prevalence

2009
Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome.
    Arthritis research & therapy, 2009, Volume: 11, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Metabolic Syndrome; Methotrexate; Prevalence

2009
Investigation of the association between metabolic syndrome and disease activity in rheumatoid arthritis.
    TheScientificWorldJournal, 2011, Jun-09, Volume: 11

    Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Iran; Logistic Models; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Prednisolone; Prevalence; Risk Assessment

2011
Evaluation of lasting high levels of CRP among the patients with metabolic syndrome.
    Inflammation, 2012, Volume: 35, Issue:2

    Topics: Adipose Tissue; Biomarkers; Body Mass Index; C-Reactive Protein; Female; Humans; Inflammation; Insulin Resistance; Intra-Abdominal Fat; Male; Metabolic Syndrome; Methotrexate

2012
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.
    Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:5

    Topics: Acitretin; Alefacept; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Psoriatic; Biological Products; Cardiovascular Diseases; Cyclosporine; Depression; Etanercept; Humans; Immunoglobulin G; Interleukin-12; Interleukin-23; Lymphoma; Metabolic Syndrome; Methotrexate; Obesity; Psoriasis; PUVA Therapy; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Smoking; Tumor Necrosis Factor-alpha

2008