methotrexate has been researched along with Meningeal Neoplasms in 311 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 180 (57.88) | 18.7374 |
| 1990's | 54 (17.36) | 18.2507 |
| 2000's | 54 (17.36) | 29.6817 |
| 2010's | 18 (5.79) | 24.3611 |
| 2020's | 5 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, H; Armstrong, GT; Berrington de Gonzalez, A; Brenner, AV; de Vathaire, F; Diallo, I; Hawkins, M; Inskip, PD; Journy, N; Neglia, JP; Stovall, MA; Tucker, MA; Veiga, LHS; Withrow, DR | 1 |
| Daily, K; Singhal, R; Wheeler, S | 1 |
| Chitambar, CR; Connelly, JM; Huang, CC; Jawa, ZA; Kapke, JT; Schneidewend, RJ | 1 |
| Hirano, Y; Ikemura, M; Kurokawa, M; Miyawaki, S; Nakatomi, H; Saito, N; Satou, M; Takayanagi, S; Tanaka, R; Tanaka, S; Taoka, K; Toyama, K | 1 |
| Arava, S; Bhatia, R; Elavarasi, A; Kumar, L | 1 |
| Dietrich, C; Hassel, JC; Herbst, R; Salzmann, M; Steinbrecher, A | 1 |
| Akai, M; Miyoshi, K; Moriyama, E; Nakagawa, T; Nomura, T; Takahashi, H; Uno, M | 1 |
| Ahmed, KA; Czerniecki, BJ; Diaz, R; Etame, AB; Evernden, B; Figura, NB; Forsyth, PA; Han, HS; Liu, J; Mohammadi, H; Mokhtari, S; Rizk, VT; Robinson, TJ; Sahebjam, S; Soliman, H; Tran, ND; Washington, I; Yu, HM | 1 |
| Ahn, JH; Ahn, SD; Ahn, SH; Gong, G; Jo, JC; Jung, KH; Kang, MJ; Kim, HH; Kim, JE; Kim, SB; Kim, SS; Son, BH | 1 |
| Dong, L; Gao, Y; Pan, Z; Wang, Y; Yang, G; Yuan, T | 1 |
| Murawska, M; Niwińska, A; Rudnicka, H | 2 |
| Kim, ST; Kim, WS; Kong, DS; Lee, JI; Lee, MH; Lim, DH; Nam, DH; Noh, JH; Seol, HJ | 1 |
| Park, MJ | 1 |
| Bang, SM; Cho, KM; Han, JH; Kim, CY; Kim, IA; Kim, JH; Kim, JS; Kim, JW; Kim, SH; Kim, YJ; Lee, JO; Lee, JS; Lee, KW | 1 |
| Baumert, BG; Glas, M; Hattingen, E; Herrlinger, U; Mack, F; Schäfer, N; Scheffler, B | 1 |
| Kordbacheh, T; Law, WY; Smith, IE | 1 |
| Dong, L; Gao, P; He, H; Li, Y; Pan, Z; Shi, W; Yang, G; Yuan, T; Zhao, G | 1 |
| Aricò, M; Tucci, F | 1 |
| Harbeck, N; Heinemann, V; Herrmann, KA; Laessig, D; Mengele, K; Schaffer, P; Schmitt, M; Stemmler, HJ | 1 |
| Ioannidis, G; Kitrou, G; Michael, M; Orphanos, G | 1 |
| Hutton, GJ; Suárez Zambrano, GA | 1 |
| Adelstein, SJ; Artignan, X; Balosso, J; Desruet, MD; Fagret, D; Gauchez, AS; Hoffmann, D; Kassis, AI; Rebischung, C; Stefani, L; Vincent, F; Vuillez, J; Wang, K; Zhang, H | 1 |
| Ando, M; Fujiwara, Y; Goto, Y; Katsumata, N; Kouno, T; Nakai, S; Sasajima, Y; Shimizu, C; Yonemori, K | 1 |
| Blot, E; Clatot, F; Guillemet, C; Laberge-Le-Couteulx, S; Nakry, T; Ouvrier, MJ; Philippin-Lauridant, G; Veyret, C | 1 |
| Bidard, FC; Cottu, PH; Dieras, V; Girre, V; Guilhaume, MN; Laurence, V; Livartowski, A; Mignot, L; Petithuguenin Gauthier, H; Pierga, JY | 1 |
| Nagpal, S; Riess, J; Wakelee, H | 1 |
| Culine, S; Gauthier, H; Kullmann, T; le Maignan, C; Szabó, A | 1 |
| Blakeley, JO; Cimino-Mathews, A; Connolly, RM; Moseley, KF; Santa-Maria, CA; Wolff, AC | 1 |
| Advani, R; Auerback, G; Batchelor, T; Cha, S; Chen, L; Damon, LE; Drappatz, J; Gerstner, E; Hwang, J; Kadoch, C; Krouwer, H; Li, J; Lowell, C; Munster, P; Rubenstein, JL; Shuman, MA | 1 |
| Cheng, AL; Huang, HC; Kuo, SH; Lin, CW | 1 |
| Antonopoulos, MJ; Gregoriou, A; Kosmas, C; Malamos, NA; Rokana, S; Stamataki, M; Tsavaris, NB; Vartholomeou, M | 1 |
| Baldus, C; Blau, IW; Fietz, T; Knauf, WU; Stoltenburg, G; Thiel, E | 1 |
| Aloulou, S; Bosq, J; Ribrag, V; Vanel, D | 1 |
| Chamberlain, MC | 2 |
| Chamberlain, MC; Cole, BF; Glantz, MJ; Jaeckle, KA; Mackowiak, JI | 1 |
| Tanaka, R; Yamamoto, K; Yoshida, S | 1 |
| SPEVAK, J | 1 |
| Fernandes, AS; Fonseca, RP; Leite, EB; Lima, VS | 1 |
| Ekinci, C; Günalp, I; Gündüz, K; Taçyildiz, N; Unal, E; Yavuz, G | 1 |
| Doki, N; Hatsumi, N; Irisawa, H; Miyawaki, S; Saito, Y; Sakura, T | 1 |
| Bang, YJ; Heo, DS; Jung, JY; Kim, DW; Kim, DY; Kim, NK; Kim, TY; Lee, KW; Park, SR; Yun, T | 1 |
| Kawaguchi, T; Kumabe, T; Tominaga, T; Watanabe, M | 1 |
| Kneppers, E; Rentinck, ME; Schrijver, HM; van Groeningen, CJ; Zijlmans, JC | 1 |
| Aikawa, S; Hatta, Y; Horie, T; Ito, T; Kanbe, E; Kitamura, K; Kura, Y; Oka, H; Saiki, M; Sawada, U; Takeuchi, J; Yamazaki, T | 1 |
| Aaronson, NK; Benraadt, J; Boogerd, W; Hart, AA; Heimans, JJ; Koehler, PJ; van den Bent, MJ; van der Sande, JJ; Vecht, ChJ | 1 |
| Kawasaki, Y; Matsushita, M; Okada, Y | 1 |
| Morii, K; Yoshida, S | 1 |
| Fukuchi, Y; Gunji, Y; Iwakami, N; Kajiyama, Y; Miura, K; Morio, Y; Ohwada, A; Sato, K; Suzuki, T; Takahashi, K; Yamamoto, A; Yoshioka, M | 1 |
| Pavlidis, N; Pentheroudakis, G | 1 |
| Bauer, S; Huber, M; Leistner, S; Nolting, M; Schmitz, U; Seyfert, S | 1 |
| Agassis, S; Baur, AS; Frossard, V; George, AC; Janzer, R; Ketterer, N; Leyvraz, S; Meuli, R; Ozsahin, M | 1 |
| Hammerer, V; Pauli, G; Quoix, E | 1 |
| Jida, M; Kubo, M; Maeda, H; Miyatani, K; Mizuta, M; Shirakawa, K; Sogabe, O; Udaka, T; Yamane, M | 1 |
| Anzai, Y; Ohta, S; Sakaue, Y; Taga, T; Takeuchi, Y | 1 |
| Bernhard, H; Harbeck, N; Heinemann, V; Lässig, D; Schmitt, M; Schoenberg, S; Stemmler, HJ; Willems, A | 1 |
| Baldini, L; Balzarotti, M; Bernardi, M; Bobbio, F; Brandes, AA; Caligaris Cappio, F; Corazzelli, G; Dell'Oro, S; Ferreri, AJ; Foppoli, M; Ilariucci, F; Montanari, M; Picozzi, P; Ponzoni, M; Reni, M; Spina, M; Stelitano, C; Tosoni, A; Zaja, F | 1 |
| Carmona-Bayonas, A | 1 |
| Hayashida, K; Iijima, N; Ishii, K; Kitazawa, K; Miura, M; Ohara, S | 1 |
| Dietemann, JL; Koob, M | 1 |
| Boogerd, W; du Bois, WF; Rosenbrand, CJ; Teepen, JL | 1 |
| Nakayama, E; Noguchi, T; Terada, Y; Yasuda, J | 1 |
| Brocca, MC; Coppi, MR; Mele, G; Melpignano, A; Pinna, S; Quarta, G; Romano, A | 1 |
| Saito, K; Shinoura, N; Tabei, Y; Takahashi, M; Yamada, R | 1 |
| Cassady, JR; Freeman, AI; Frei, E; Green, DM; Hammond, D; Nesbit, ME; Sallan, SE; Sather, HN; Sinks, LF | 1 |
| Krebs, LU; Robinson, WA | 1 |
| Abromowitch, M; Bowman, WP; Mason, C; Ochs, JJ; Pui, CH; Simone, JV | 1 |
| Kammerer, R; Mittler, U; Otto, HJ; Wittwer, B | 1 |
| Blumenschein, GR; Hortobagyi, GN; Levens, ME; Rasmussen, S; Yap, BS; Yap, HY | 1 |
| Bowman, WP; Campbell, M; Ch'ien, L; Coburn, T; Ochs, JJ; Parvey, LS; Whitaker, JN | 1 |
| Canellos, GP; Case, DC; Frei, E; MacIntyre, JM; Moloney, WC; Pinkus, GS; Rosenthal, DS; Skarin, AT | 1 |
| Dietrich, J; Metz, O; Plenert, W | 1 |
| Markman, M | 1 |
| Aroney, RS; Bell, DR; Chan, WK; Dalley, DN; Levi, JA | 1 |
| Metz, O; Stoll, W | 1 |
| Metz, O; Plenert, W; Stoll, W | 1 |
| Deckert, H; Döge, H; Dörffel, W; Metz, O; Mittler, U; Plenert, W; Redemann, H; Rönisch, P; Stoll, W; Zastrow, J | 1 |
| Döge, H; Hliscs, R | 1 |
| Dommasch, D; Mertens, HG | 1 |
| Schöck, V | 1 |
| Frei, E | 1 |
| Hildebrand, J; Seeldrayers, P | 1 |
| Cassileth, PA | 1 |
| Azuma, I; Chatani, M; Hishikawa, Y; Inoue, T; Kondo, K; Kumano, M; Suyama, T; Tabata, S; Teshimá, T; Yabumoto, E | 1 |
| Collins, JM | 1 |
| Fujimoto, T | 3 |
| Anderson, T; Hansen, RM; Hanson, GA; Kun, LE; Orlowski, EP; Pisciotta, AV | 1 |
| Mauro, A | 1 |
| Burchenal, JH | 1 |
| Arizaga, R; Castaño, J; Chamoles, N; Fisman, N; Leiguarda, R; Moreno, R; Pavlovsky, S | 1 |
| Javier, G; Montagut, JM; Ortega, JJ | 1 |
| Cherian, R; Lin, HP; Menaka, N; Singh, P; Sinnah, D | 1 |
| Bowman, WP; Dahl, GV; George, SL; Hustu, HO; Kalwinsky, D; Ochs, J; Rivera, G; Simone, JV | 1 |
| Ishiwata, Y; Kuwabara, T; Kyuma, Y; Murai, M; Nishimura, S; Shinonaga, M; Yamashita, T | 1 |
| Barber, SW; Camitta, BM; Casper, JT; Kamen, BA; Kaplan, BM; Kline, RW; Kun, LE; Lauer, SJ; Mulhern, RK | 1 |
| Azuma, I; Chatani, M; Hishikawa, Y; Inoue, T; Kondo, K; Kumano, M; Nakajima, T; Suyama, T; Teshima, T; Yabumoto, E | 1 |
| Hattori, S; Kitajima, K; Nagashima, H; Sato, Y; Watanabe, A | 1 |
| Hammond, GD; Meadows, AT; Nesbit, ME; Ortega, JA; Robison, LL; Sather, HN | 1 |
| Baĭdurin, SA; Iungbliut, AA; Stechnaia, VN | 1 |
| Boiron, M; Janvier, M; Leverger, G; Poirier, O; Renier, D; Tobelem, G | 1 |
| Behrendt, H | 1 |
| Hatakeyama, S; Okeda, R; Suzuki, K; Takemura, T | 1 |
| Hamborg-Pedersen, B; Lund, E | 1 |
| Glass, JP; Mehta, BM; Shapiro, WR | 1 |
| Hart, AA; McVie, JG; Nooyen, WH; Ongerboer de Visser, BW; Somers, R; van Heerde, P | 1 |
| Delle Grottaglie, B; Ghisolfi, A; Girotti, F; Pescia, M; Tafi, A | 1 |
| Abdyldaev, RA; Finogenova, IA; Kruglova, GV; Tarasiuk, SV | 1 |
| Edwards, B; Janus, C; Magrath, I; Sariban, E | 1 |
| Bodey, GP; Gordon, AN; Kavanagh, JJ; Obbens, EA; Rutledge, FN; Wharton, JT | 1 |
| Fauchon, F; Foncin, JF; Herson, D; Rouques, C | 1 |
| Galbo, C; Lokich, J | 1 |
| Edwards, MS; Levin, VA; Seager, ML; Wilson, CB | 1 |
| Grossman, SA; Murray, K; Thompson, G; Trump, DL | 1 |
| Grossman, SA; Murray, K; Thompson, G; Trump, DL; Wharam, M | 1 |
| Chessells, JM | 1 |
| Camargo, EE; Chen, DC; Grossman, SA; Thompson, G; Trump, DL | 1 |
| Liepman, MK; Votaw, ML | 1 |
| Glass, JP; Posner, JB; Wasserstrom, WR | 1 |
| Ojeda, VJ | 1 |
| Gargan, R | 1 |
| Korinthenberg, R; Palm, D | 1 |
| Auclerc, MF; Bernard, J; Jacquillat, C; Schaison, G; Weil, M | 1 |
| Moss, HA; Nannis, ED; Poplack, DG | 1 |
| Boiadzhiev, P; Petkova, R; Vasilev, N | 1 |
| Akao, Y; Hiraiwa, A; Naito, K; Nakamara, K; Naoe, T; Uno, H; Yamaguchi, H; Yoshikawa, H; Yoshikawa, S | 1 |
| Breton, MP; Cau, D; Dommergues, JP; Jacque, C; Laurian, Y; Tchernia, G | 1 |
| Weil, M | 1 |
| Chervinsky, DS; Creaven, PJ; Ettinger, LJ; Freeman, AI | 1 |
| Ghavimi, F; Miller, DR; Murphy, ML; Nir, Y; Salwen, R; Tamaroff, M | 1 |
| Alessandrino, EP; Bernasconi, C; Brusamolino, E; Canevari, A; Castelli, G; Isernia, P; Lazzarino, M; Morra, E; Orlandi, E; Pagnucco, G; Salvaneschi, L; Zei, G | 1 |
| de Vassal, F; Delgado, M; Gil-Delgado, MA; Goutner, A; Machover, D; Mathé, G; Misset, JL | 1 |
| Gendelman, S; Theodore, WH | 1 |
| Bakshi, S; Berger, P; Brecher, ML; Ettinger, LJ; Freeman, AI; Green, DM; Parthasarathy, KL; West, CR | 1 |
| Malarme, M; Stryckmans, PA | 1 |
| Fisman, N; Garay, G; Pavlovsky, S | 1 |
| D'Angio, GJ; Donaldson, M; Hammond, D; Hittle, R; Littman, P; Nesbit, M; Ortega, J; Sather, H | 1 |
| Luedke, SL; Marr, JJ; Palitang, EG; Sutherland, GE | 1 |
| Bremer, AM; Hayakawa, T; Mogami, H; Ushio, Y; West, CR; Yamada, K | 2 |
| Bots, GT | 1 |
| Carpentier, AF; Chantelard, JV; Henin, D; Poisson, M | 1 |
| Galindo, C; Gómez-Almaguer, D; González-Llano, O; Jaime-Pérez, JC; Montemayor, J | 1 |
| Feun, L; Landy, H; Markoe, AM; Snodgrass, SM | 1 |
| Giamundo, A; Iaconetta, G; Lamaida, E; Manto, A; Rossi, A; Signorelli, F | 1 |
| Goto, K; Hara, Y; Kobayashi, Y; Mochizuki, M; Tokue, A; Tozuka, K | 1 |
| Mazingue, F; Mechinaud, F; Millot, F; Rubie, H; Thyss, A | 1 |
| Bacher, JD; Balis, FM; Godwin, KS; McCully, CL | 1 |
| Khalil, AM; Mroueh, AM; Salem, ZM; Tabbal, SD; Yamout, BI | 1 |
| Byrne, GE; Glaser, JS; Kay, MD; Liu, GT; Schatz, N | 1 |
| Engels, B; Hartmann-Klosterkötter, U; Heider, A; Kress, M; Niederle, N | 1 |
| Ettinger, DS; Finkelstein, DM; Grossman, SA; Moynihan, T; Ruckdeschel, JC; Trump, DL | 1 |
| Davila, G; Delattre, JY; Duyckaerts, C; Lazareth, JP; Poisson, M | 1 |
| Asselain, B; Beuzeboc, P; Dieras, V; Dorval, T; Fizazi, K; Jouve, M; Palangie, T; Pouillart, P; Vincent-Salomon, A | 1 |
| Fujita, T; Hayakawa, T; Izumoto, S; Kubo, S; Nakagawa, H; Nakajima, Y; Tokiyoshi, K; Tsuruzono, K | 1 |
| Chamberlain, MC; Kormanik, PA | 2 |
| Deeb, LS; Shabb, NS; Shamseddine, AI; Uthman, SM; Yamout, BI | 1 |
| Dufour, P; Korganov, AS; Maloisel, F; Oberling, F; Petit, T | 1 |
| Barba, D; Chamberlain, MC; Kormanik, PA | 1 |
| Zyluk, B | 1 |
| DeAngelis, LM; Mason, WP; Yeh, SD | 1 |
| Barral, FG; Beauchesne, P; Clavreul, G; Duthel, R; Laurent, B; Pialat, J; Schmitt, T | 1 |
| Obwegeser, A; Seiwald, M; Stockhammer, G | 1 |
| Lyn, BE; Mahendra, P; McMillan, AM; Shaw, B; Somers, LJ | 1 |
| Adamson, PC; Balis, FM; Gillespie, AJ; Moser, AM; Poplack, DG | 1 |
| Bleyer, WA | 3 |
| Chamberlain, MC; Cole, BF; Glantz, MJ; Howell, SB; Jaeckle, KA; LaFollette, S; Maria, B; Phuphanich, S; Recht, L; Schumann, GB; Swinnen, LJ | 1 |
| Arita, N; Hayakawa, T; Huang, TY; Ushio, Y | 1 |
| Choi, D; Seex, K | 1 |
| Akman, S; Carroll, MI; Doroshow, JH; Leong, LA; Longmate, JA; Margolin, KA; Morgan, RJ; Newman, EM; Raschko, JW; Slatkin, N; Somlo, G; Tetef, ML | 1 |
| Adami, F; Bassi, R; Del Colle, R; Gioga, G; Pea, M; Silvestri, M; Turazzini, M | 1 |
| Antonopoulos, M; Kosmas, C; Malamos, NA; Tsavaris, N | 1 |
| Kastenbauer, S; Pfister, HW; Wiesmann, M | 1 |
| Aiyoshi, Y; Hara, H; Igarashi, A; Ueno, E; Yano, Y; Yashiro, T | 1 |
| Bernardi, M; Camba, L; Ciceri, F; Dell'Oro, S; Ferreri, AJ; Ponzoni, M; Reni, M; Spina, M; Terreni, MR; Tomirotti, M; Villa, E | 1 |
| Belloc, J; Boige, V; Delaunoit, T; Ducreux, M; Duvillard, P; Elias, D; Lasser, P | 1 |
| Brauckhoff, M; Kamprad, M; Steuber, J | 1 |
| Hochberg, FH; Tabatabai, G | 1 |
| Jokura, H; Kumabe, T; Saito, R; Yoshimoto, T | 1 |
| Anderson, JR; Breneman, JC; Crist, WM; Donaldson, SS; Fitzgerald, TJ; Fryer, CJ; Gehan, EA; Maurer, HM; Meza, J; Michalski, JM; Ortega, JA; Qualman, SJ; Raney, RB; Sandler, E; Wharam, MD; Wiener, ES | 1 |
| Brick, WG; Burgess, RE; Hendricks, LK; Jillella, AP; Kallab, AM; Majmundar, M | 1 |
| Antonopoulos, MJ; Gregoriou, A; Kosmas, C; Malamos, NA; Rokana, S; Stamataki, M; Stefanou, S; Tsavaris, NB; Vartholomeou, M | 1 |
| Abelson, HT; Fosburg, M; Gorka, C; Kornblith, P | 1 |
| Bleyer, WA; Oliff, A; Poplack, DG | 1 |
| Castells-van Daele, M; van de Casseye, W | 1 |
| Engelhardt, P; Lorenz, R | 1 |
| Magrath, IT; Olweny, CL; Ziegler, JL | 1 |
| Kogelnik, HD; Krepler, P; Pichler, E; Reinartz, G; Schmidmeier, W | 1 |
| Begeer, JH; Ebels, EJ; Mehta, DM; Piers, DA; Postma, A | 1 |
| Blom, J; Law, IP | 1 |
| Adornato, BT; Di Chiro, G; Peylan-Ramu, N; Pizzo, PA; Poplack, DG | 1 |
| Benjamin, DR; Bleyer, WA; Kolins, CJ; Pizzo, PA; Platt, WD; Poplack, DG; Spence, AM | 1 |
| Amadori, S; De Lipsis, E; Grignani, F; Liso, V; Mandelli, F; Martelli, M | 1 |
| Maekawa, T; Moteki, M; Omine, M; Shimano, S; Shinonome, S; Suda, T; Tsuchiya, J | 1 |
| Armata, J; Borkowski, W; Cyklis, R | 1 |
| Aur, RJ; George, SL; Mauer, AM; Simone, JV | 1 |
| Aspnes, GT; Capizzi, RL; Lobel, JS; McIntosh, S; O'Brien, RT | 1 |
| Avenarius, HJ; Engelhardt, P; Lohmann, E; Lorenz, R | 1 |
| Koelmel, HW; Weizsaecker, M | 1 |
| Canellos, GP; Frei, E; Moloney, W; Pitman, SW; Rosenthal, DS; Skarin, AT; Zuckerman, KS | 1 |
| Mauer, AM | 1 |
| Frei, E; Sallan, SE | 1 |
| Glicksman, AS; Tefft, M | 1 |
| Konchakova, MI; Kruglova, GV | 1 |
| Price, RA | 1 |
| Filler, J; Humphrey, GB; Krous, HF; Maxwell, JD; VanHoutte, JJ | 1 |
| Freund, M; Ostendorf, P; Waller, HD | 1 |
| Amiel, JL | 1 |
| Borderas, F; Gil, JL; Giralt, M; Gomez-Pereda, R; Martinez-Ibañez, F; Oliveros, A; Pardo, J; Raichs, A | 1 |
| Murphy, MJ | 1 |
| Allen, JC; Hasegawa, H; Mehta, BM; Posner, JB; Shapiro, WR | 1 |
| Anan, S; Ashizawa, A; Fujimoto, J; Furusho, M; Goya, N; Hasegawa, K; Hirakawa, K; Hiyoshi, Y; Ito, M; Jingu, K; Kawahira, K; Kim, PY; Kurauchi, S; Matsuoka, J; Matsuura, K; Nose, K; Ono, Y; Oobtake, H; Yokoyama, T | 1 |
| Kádár, A; Péter, A | 1 |
| Fujisawa, H; Hanawa, M | 1 |
| Koide, R; Taguchi, N | 1 |
| Blumenschein, GR; Buzdar, AU; Krutchik, AN; Tashima, CK | 1 |
| Bleyer, WA; Poplack, DG; Simon, RM | 1 |
| Blumenschein, GR; DiStefano, A; Tashima, CK; Yap, BS; Yap, HY | 1 |
| Karp, G; Nahum, K | 1 |
| Bashir, RM; Foley, J; Gasecki, AP | 1 |
| Quah, TC; Siegel, SE; White, L | 1 |
| Frick, J; Jakse, G; Mack, D | 1 |
| Hayakawa, T; Izumoto, S; Kubo, S; Murasawa, A; Nakagawa, H; Nakajima, S; Nakajima, Y | 2 |
| Balis, FM; Blaney, SM; Poplack, DG | 2 |
| Fujimoto, T; Koizumi, S; Mimaya, J; Ninomiya, T; Ohta, S; Sasaki, K; Takaue, Y; Takeda, T; Utsumi, J | 1 |
| de Wolff, FA; Edelbroek, PM; Keizer, HJ; Schweitzer, DH | 1 |
| Artigas, J; Cervos-Navarro, J; Cruz-Sanchez, FF; Ferszt, R; Rossi, ML | 1 |
| Hochberg, FH; Loeffler, JS; Prados, M | 1 |
| Boogerd, W; Engelsman, E; Hart, AA; van der Sande, JJ | 1 |
| Regli, L; Teta, D; Uldry, PA | 1 |
| Hart, AA; Nooyen, WJ; Ongerboer de Visser, BW; Twijnstra, A; van Heerde, P; van Zanten, AP | 1 |
| Chye, RW; Raghavan, D | 1 |
| Fujita, T; Izumoto, S; Kubo, S; Nakagawa, H; Nakajima, Y; Tsuruzono, K | 1 |
| Muggia, F | 1 |
| Hayani, A; Laurent, JP; Mahoney, DH; McClain, KL; Rouah, E; Venger, BH | 1 |
| Dörffel, W; Malke, H; Reimann, M; Reuter, G; Zintl, F | 1 |
| Frampton, CM; Hart, DN; Jeffery, GM; Legge, HM | 1 |
| Balter, R; Borgna-Pignatti, C; Caraballo, R; Colamaria, V; Dalla Bernardina, B; Marradi, P; Mazza, C; Procacci, C | 1 |
| Bishop, JR; Maldonado, L; McLeod, DG; Moul, JW | 1 |
| Boogerd, W; Moffie, D; Smets, LA | 1 |
| Barnett, MJ; Phillips, GL; Shore, T | 1 |
| Arita, N; Hayakawa, T; Mogami, H; Ushio, Y | 1 |
| Hoppe, RT | 1 |
| Connors, JM; Klimo, P | 1 |
| Cuthbert, RJ; Parker, AC; Sheehan, T | 1 |
| Ochs, JJ | 1 |
| Behrendt, H; Hermans, J; Schuwirth, C; van der Does-van den Berg, A; van Leeuwen, EF; van Wering, ER; Verkes, RJ | 1 |
| Alessandrino, EP; Bernasconi, P; Canevari, A; Inverardi, D; Lazzarino, M; Morra, E; Orlandi, E; Pagnucco, G; Regazzi Bonora, M; Rondanelli, R | 1 |
| Miller, KT; Wilkinson, DS | 1 |
| Donnelly, E; Feun, LG; Ganjei, P; Hussein, AM; Savaraj, N | 1 |
| Ablin, AR; Albo, VC; Bleyer, WA; Finklestein, JZ; Gaynon, PS; Grossman, NJ; Littman, PS; Novak, LT; Pyesmany, AF; Steinherz, PG | 1 |
| Bobin, JY; Clavel, M; Guastalla, JP; Ranchere, JY | 1 |
| Giannone, L; Greco, FA; Hainsworth, JD | 1 |
| Singh, AK; Thompson, RP | 1 |
| Javier, G; Olive, T; Ortega, JJ | 1 |
| Di Bella, D; Lo Bianco, M; Rizzari, C; Russo, A; Schilirò, G | 1 |
| Higashino, H; Kobayashi, Y; Nishikawa, A; Nobori, U | 1 |
| Kobayashi, T | 1 |
| Daenen, S; Haaxma-Reiche, H | 1 |
| Poburski, R; Wiehler, S | 1 |
| Daud, AB; Lin, HP; Nuruddin, RN | 1 |
| ten Hoeve, RF; Twijnstra, A | 1 |
| Blatt, J; Finegold, D; Lee, P; Suttner, J | 1 |
| Killander, A; Simonsson, B; Smedmyr, B; Sundström, C | 1 |
| Colly, LP; Peters, WG; Willemze, R | 1 |
| Asada, Y; Ishikawa, M; Kohga, S; Nakamura, H; Sumiyoshi, A | 1 |
| Boogerd, W; Moffie, D; vd Sande, JJ | 1 |
| Crowley, J; Eyre, HJ; Molnar, B; Pugh, RP; Quagliana, JM; Rivkin, SE; Sause, WT; Taylor, SA | 1 |
| Malke, H; Plenert, W; Zintl, F | 1 |
| Bleyer, WA; Coccia, P; Hammond, D; Littman, P; Lukens, J; Miller, D; Sather, H; Siegel, S | 1 |
| D'Angio, GJ; Hammond, GD; Nesbit, ME; Ortega, JA; Robison, LL; Sather, HN | 1 |
| Bell, DR; Hitchins, RN; Levi, JA; Woods, RL | 1 |
| Cano, JP; Carcassonne, Y; Guérin, B; Lejeune, C; Payet, B; Tubiana, N | 1 |
| Carbone, G; Leone, G; Marra, R; Massaro, A; Pagano, L; Storti, S; Teofili, L | 1 |
| Bernasconi, C; Brusamolino, E; Canevari, A; Inverardi, D; Lazzarino, M; Morra, E; Orlandi, E; Pagnucco, G | 1 |
| Maaser, M; Metz, O | 1 |
| Fujimoto, T; Kawai, S | 1 |
| Fujimoto, T; Matsuoka, H; Sasaki, K | 1 |
| Fujimoto, T; Kadoya, S; Koizumi, S; Mimaya, J; Miyao, M; Ninomiya, T; Nishikawa, K; Tsuda, Y; Utsumi, J; Yatabe, M | 1 |
| Gomis, F; Javier Rafecas, F; Lorenzo, IJ; Martín-Aragonés, G; Martínez, JA; Marty, ML; Sanz, GF; Sanz, MA; Sayas, MJ | 1 |
| Brandeis, WE; Frei, E; Kimmig, B; Ludwig, R | 1 |
| Chiba, Y; Haneda, Y; Iwamura, H; Kawamura, S; Mikami, T; Sakata, Y; Sawada, Y; Yamaya, T; Yoshida, Y | 1 |
| Buckner, CD; Flournoy, N; Sanders, JE; Thomas, ED; Thompson, CB | 1 |
| Javier, G; Montagut, JM; Ortega, JJ; Torán, N | 1 |
| Davis, KS; Williams, JM | 1 |
| Fuks, Z; Mandell, LR; Wollner, N | 1 |
| Gumbart, CH; Stagg, MP | 1 |
| Kim, TH; Nesbit, ME; Ramsay, NK; Steeves, RA | 1 |
| Abrahamsen, AF; Dahl, IM; Holte, H; Saeter, G | 1 |
| Bernstein, JI; Coleman, CN; Dorfman, RF; Rosenberg, SA; Strickler, JG | 1 |
| Adam, T; Heidemann, E; Kloeter, I; Schabet, M; Wiethölter, H | 1 |
| Balis, F; Bleyer, A; Feusner, J; Miser, J; Morse, M; Poplack, D; Reaman, G; Savitch, J | 1 |
| Balis, FM; Bleyer, WA; Poplack, DG; Reaman, GH; Savitch, JL | 1 |
| Galicich, J; Jereb, B; Steinherz, P | 1 |
| Thiel, HJ | 1 |
| Lokey, JL; Pecora, M; Steinberg, JP | 1 |
| Boyett, J; Crist, W; Doering, EJ; Hvizdala, E; Pullen, J; Ruymann, F; Steuber, CP; Sullivan, MP; Trueworthy, R | 1 |
| Bodey, GP; Freireich, EJ; Hurtubise, M; Keating, MJ; Leavens, M; Maor, M; McCredie, KB; Smith, TL; Stewart, DJ | 1 |
| Flournoy, N; Livingston, RB; Mortimer, J; Stephens, RL | 1 |
| Sculier, JP | 1 |
| Patchell, RA; Posner, JB | 1 |
| Horikoshi, N; Inagaki, J; Inoue, K; Ogawa, M; Takagi, K; Takano, Y; Usui, N | 1 |
| Dekker, AW; Elderson, A; Punt, K; Sixma, JJ | 1 |
| Hardisty, RM; Norman, PM | 1 |
38 review(s) available for methotrexate and Meningeal Neoplasms
| Article | Year |
|---|---|
High-dose intravenous methotrexate in the management of breast cancer with leptomeningeal disease: Case series and review of the literature.
Topics: Aged; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Quality of Life | 2019 |
Leptomeningeal metastases from a primary central nervous system melanoma: a case report and literature review.
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Chemoradiotherapy; Female; Humans; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Tomography, X-Ray Computed | 2014 |
Durable Response of Leptomeningeal Metastasis of Breast Cancer to Salvage Intrathecal Etoposide After Methotrexate: A Case Report and Literature Review.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Etoposide; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Salvage Therapy | 2015 |
Therapy of leptomeningeal metastasis in solid tumors.
Topics: Antineoplastic Agents; Cytarabine; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Neoplasm Seeding; Neoplasm Staging; Radiotherapy; Thiotepa; Treatment Outcome | 2016 |
Sanctuary site leptomeningeal metastases in HER-2 positive breast cancer: A review in the era of trastuzumab.
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged; Receptor, ErbB-2; Spinal Cord Neoplasms; Trastuzumab | 2016 |
Carcinomatous meningitis in cancer of the uterine cervix.
Topics: Antimetabolites, Antineoplastic; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Uterine Neoplasms | 2004 |
Management of leptomeningeal malignancy.
Topics: Adenocarcinoma; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Arachnoid Cysts; Carcinoma; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Delayed-Action Preparations; Enzyme Inhibitors; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Palliative Care; Randomized Controlled Trials as Topic; Thiotepa; Topoisomerase I Inhibitors; Topotecan | 2005 |
[Guideline 'Leptomeningeal metastases of solid tumours'].
Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Cranial Irradiation; Diagnosis, Differential; Humans; Karnofsky Performance Status; Meningeal Neoplasms; Meninges; Methotrexate; Neoplasm Metastasis; Neoplasms; Neurologic Examination; Practice Guidelines as Topic; Prognosis | 2007 |
Acute leukemia in children. Model for the development of scientific methodology for clinical therapeutic research in cancer.
Topics: Acute Disease; Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cell Division; Child; Child, Preschool; Clinical Trials as Topic; Hodgkin Disease; Humans; Infant; Kinetics; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Mice; Models, Biological | 1984 |
Treatment of neoplastic meningitis.
Topics: Adult; Antineoplastic Agents; Child; Combined Modality Therapy; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Radiotherapy | 1984 |
Adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged; Thioguanine | 1984 |
Acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Asparaginase; B-Lymphocytes; Bacterial Infections; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukocyte Count; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisolone; T-Lymphocytes; Testicular Neoplasms; Vincristine | 1982 |
[Prophylactic treatment of meningeal leukemia (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Nitrosourea Compounds; Radiation Injuries; Radiotherapy Dosage | 1981 |
[Prevention of leukemia of the central nervous system. Results of different therapeutic methods and toxic effects].
Topics: Brain; Dexamethasone; Humans; Hypothalamo-Hypophyseal System; Intelligence; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Radiotherapy; Sleep Wake Disorders; Tomography, X-Ray Computed | 1981 |
Leptomeningeal carcinomatosis: review of the literature.
Topics: Carcinoma; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Humans; Immunotherapy; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate | 1994 |
[A case of carcinomatous meningitis from transitional cell carcinoma of the urinary bladder].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Humans; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Urinary Bladder Neoplasms; Vinblastine | 1994 |
Case report and review of literature: leptomeningeal relapse in epithelial ovarian cancer.
Topics: Adult; Aged; Brain; Combined Modality Therapy; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Ovarian Neoplasms; Recurrence | 1994 |
Diffuse primary leptomeningeal gliomatosis.
Topics: Adult; Astrocytoma; Brain Neoplasms; Cranial Irradiation; Hippocampus; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Neoplasms, Unknown Primary | 1993 |
Meningeal carcinomatosis as the presenting manifestation of gastric adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Doxorubicin; Fluorouracil; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms | 1997 |
Aggressive treatment with complete remission in primary diffuse leptomeningeal gliomatosis--a case report.
Topics: Adolescent; Antimetabolites, Antineoplastic; Cerebrospinal Fluid Shunts; Combined Modality Therapy; Glioma; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Remission Induction | 1998 |
Chemotherapy-induced complete regression of choroidal metastases and subsequent isolated leptomeningeal carcinomatosis in advanced breast cancer: a case report and literature review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Choroid Neoplasms; Combined Modality Therapy; Docetaxel; Female; Humans; Meningeal Neoplasms; Methotrexate; Mitoxantrone; Paclitaxel; Survival Analysis; Taxoids | 2000 |
Therapy of PCNSL at the Massachusetts General Hospital with high dose methotrexate and deferred radiotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Boston; Brain Neoplasms; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Dexamethasone; Doxorubicin; Eye Neoplasms; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Prednisone; Radiotherapy, Adjuvant; Remission Induction; Time Factors; Treatment Outcome; Vincristine | 2001 |
Leukemic leptomeningeal involvement in stage 0 and stage 1 chronic lymphocytic leukemia.
Topics: Aged; Brain Diseases; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemic Infiltration; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Treatment Outcome | 2002 |
Acute lymphoblastic leukemia: treatment.
Topics: Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunotherapy; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Prognosis; Recurrence; Remission, Spontaneous; Spinal Cord Neoplasms | 1978 |
The role of radiotherapy in the management of acute lymphocytic leukemia.
Topics: Antineoplastic Agents; Blindness; Brain Neoplasms; Child; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiation Injuries; Spinal Cord Neoplasms | 1978 |
Histopathology of CNS leukemia and complications of therapy.
Topics: Blood-Brain Barrier; Brain; Calcinosis; Child; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug-Related Side Effects and Adverse Reactions; Humans; Leukemia; Leukoencephalopathy, Progressive Multifocal; Meningeal Neoplasms; Methotrexate; Radiotherapy; Vascular Diseases | 1979 |
Treatment of overt CNS leukemia.
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Blood-Brain Barrier; Carmustine; Child; Cytarabine; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate; Pyrimethamine | 1979 |
Leptomeningeal carcinomatosis: a report of 3 cases and review of the literature.
Topics: Adult; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Small Cell; Cytarabine; Diagnosis, Differential; Female; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Myelography; Prednisone; Vincristine | 1992 |
Non-Hodgkin's lymphomas in children. II. Treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Doxorubicin; Humans; Immunologic Factors; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Prednisolone; Prednisone; Prognosis; Remission Induction; Survival Rate; Vincristine | 1992 |
Current pharmacological treatment approaches to central nervous system leukaemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Evaluation; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Methotrexate | 1991 |
The therapy of primary brain lymphoma.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Evaluation Studies as Topic; Eye Neoplasms; Humans; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Life Tables; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Radiotherapy; Spinal Neoplasms; Survival Rate; Transplantation | 1991 |
Transient focal leukoencephalopathy following intraventricular methotrexate and cytarabine. A complication of the Ommaya reservoir: case report and review of the literature.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Cytarabine; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
The role of radiation therapy in the management of the non-Hodgkin's lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Follow-Up Studies; Humans; Leucovorin; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Mycosis Fungoides; Palliative Care; Prednisone; Radiotherapy Dosage; Skin Neoplasms; Time Factors; Vincristine; Whole-Body Irradiation | 1985 |
Neurotoxicity due to central nervous system therapy for childhood leukemia.
Topics: Central Nervous System; Child; Cytarabine; Humans; Meningeal Neoplasms; Methotrexate; Neurosecretory Systems; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Central nervous system leukemia.
Topics: Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage | 1988 |
Central nervous system prophylactic treatment for childhood leukemia: neuropsychological outcome studies.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Female; Humans; Infant; Intelligence Tests; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Quality of Life; Radiotherapy; Stress, Psychological | 1986 |
Treatment of meningeal carcinomatosis.
Topics: Antineoplastic Agents; Blood-Brain Barrier; Combined Modality Therapy; Humans; Immunotherapy; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate | 1985 |
Neurologic complications of systemic cancer.
Topics: Arachnoid; Bacterial Infections; Brain; Brain Neoplasms; Cerebrovascular Disorders; Cisplatin; Disseminated Intravascular Coagulation; Electroencephalography; Endocarditis; Fluorouracil; Humans; Lung Neoplasms; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Paraneoplastic Syndromes; Pia Mater; Prognosis; Spinal Cord Compression; Spinal Cord Neoplasms; Tomography, X-Ray Computed; Vinca Alkaloids | 1985 |
45 trial(s) available for methotrexate and Meningeal Neoplasms
| Article | Year |
|---|---|
Concurrent radiotherapy and intrathecal methotrexate for treating leptomeningeal metastasis from solid tumors with adverse prognostic factors: A prospective and single-arm study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemoradiotherapy; Dexamethasone; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Treatment Outcome | 2016 |
Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intraventricular; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Rituximab | 2013 |
Isolated leptomeningeal carcinomatosis (carcinomatous meningitis) after taxane-induced major remission in patients with advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Combined Modality Therapy; Disease Progression; Docetaxel; Female; Humans; Incidence; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Neoplasm Staging; Paclitaxel; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Taxoids | 2002 |
Quality-of-life-adjusted survival comparison of sustained-release cytosine arabinoside versus intrathecal methotrexate for treatment of solid tumor neoplastic meningitis.
Topics: Adult; Cytarabine; Delayed-Action Preparations; Disease Progression; Humans; Injections, Spinal; Meningeal Neoplasms; Meningitis; Methotrexate; Neoplasms; Quality of Life; Survival Analysis | 2003 |
The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Injections, Intraventricular; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged; Survival Analysis; Treatment Outcome | 2004 |
Approaching an individual methotrexate regimen in leptomeningeal carcinomatosis.
Topics: Adult; Aged; Albumins; Carcinoma; Female; Humans; Immunosuppressive Agents; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Time Factors | 2005 |
MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Hematologic Diseases; Humans; Idarubicin; Life Tables; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Remission Induction; Stroke; Survival Analysis; Thiotepa | 2006 |
Breast cancer leptomeningeal metastasis--the role of multimodality treatment.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Dexamethasone; Disease-Free Survival; Humans; Infusions, Intravenous; Injections, Spinal; Kaplan-Meier Estimate; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy; Statistics, Nonparametric; Treatment Outcome | 2007 |
Continuous intrathecal treatment with methotrexate via subcutaneous port: implication for leptomeningeal dissemination of malignant tumors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Injections, Spinal; Kaplan-Meier Estimate; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neuronavigation | 2008 |
Serial cranial computed-tomography scans in children with leukemia given two different forms of central nervous system therapy.
Topics: Adolescent; Brain; Child; Child, Preschool; Combined Modality Therapy; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Myelin Basic Protein; Tomography, X-Ray Computed | 1983 |
Newer techniques in cancer chemotherapy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bleomycin; Bone Marrow Transplantation; Carcinoma; Cells, Cultured; Child; Cisplatin; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hepatic Artery; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Mechlorethamine; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Osteosarcoma; Peritoneal Cavity; Pleura | 1984 |
[High-dosage intralumbar methotrexate administration. A report on clinical experience].
Topics: Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Lumbosacral Region; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local | 1983 |
Acute leukemia in children. Model for the development of scientific methodology for clinical therapeutic research in cancer.
Topics: Acute Disease; Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cell Division; Child; Child, Preschool; Clinical Trials as Topic; Hodgkin Disease; Humans; Infant; Kinetics; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Mice; Models, Biological | 1984 |
Factors associated with IQ scores in long-term survivors of childhood acute lymphoblastic leukemia.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Humans; Infant; Intelligence; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage; Sex Factors; Wechsler Scales | 1984 |
Treatment of neoplastic meningitis with intraventricular thiotepa and methotrexate.
Topics: Adult; Aged; Clinical Trials as Topic; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Thiotepa | 1982 |
The effects of prophylactic treatment of the central nervous system on the intellectual functioning of children with acute lymphocytic leukemia.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Humans; Infant; Injections, Spinal; Intelligence; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Wechsler Scales | 1981 |
Evaluation of radiation therapy factors in prophylactic central nervous system irradiation for childhood leukemia: a report from the Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy; Random Allocation | 1981 |
Dexamethasone in the treatment of meningeal leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Cytarabine; Dexamethasone; Humans; Infant; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged | 1995 |
Cerebrospinal fluid drug levels of leukemic children receiving intravenous 5 g/m2 methotrexate.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Infant; Infusions, Intravenous; Leucovorin; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Risk Factors | 1994 |
Randomized prospective comparison of intraventricular methotrexate and thiotepa in patients with previously untreated neoplastic meningitis. Eastern Cooperative Oncology Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Female; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Prospective Studies; Survival Analysis; Thiotepa; Treatment Outcome | 1993 |
Meningeal carcinomatosis in patients with breast carcinoma. Clinical features, prognostic factors, and results of a high-dose intrathecal methotrexate regimen.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Injections, Spinal; Leucovorin; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Retrospective Studies | 1996 |
Ventriculolumbar perfusion chemotherapy with methotrexate and cytosine arabinoside for meningeal carcinomatosis: a pilot study in 13 patients.
Topics: Adult; Aged; Carcinoembryonic Antigen; Carcinoma; Cell Count; Cerebrospinal Fluid; Confusion; Cytarabine; Female; Fever; Glucuronidase; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Nausea; Pilot Projects; Sensation Disorders; Subarachnoid Space; Treatment Outcome | 1996 |
[Neuropathologic evaluation of intrathecal prophylaxis results in adults with high grade non-Hodgkin's lymphomas].
Topics: Adult; Aged; Arachnoid; Controlled Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukocyte Count; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Pia Mater; Retrospective Studies; Risk Factors; Spinal Nerve Roots | 1997 |
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cytarabine; Delayed-Action Preparations; Disease Progression; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Survival Rate; Survivors | 1999 |
Pharmacokinetics and toxicity of high-dose intravenous methotrexate in the treatment of leptomeningeal carcinomatosis.
Topics: Adult; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leucovorin; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Osteosarcoma | 2000 |
Cure of Burkitt's lymphoma. Ten-year follow-up of 157 Ugandan patients.
Topics: BCG Vaccine; Burkitt Lymphoma; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Follow-Up Studies; Humans; Meningeal Neoplasms; Methotrexate; Random Allocation; Remission, Spontaneous; Time Factors; Vincristine | 1979 |
Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervous system with radiation and intrathecal chemotherapy.
Topics: Adolescent; Brain; Child; Child, Preschool; Cytarabine; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Tomography, X-Ray Computed | 1978 |
Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1978 |
"Concentration x time" methotrexate via a subcutaneous reservoir: a less toxic regimen for intraventricular chemotherapy of central nervous system neoplasms.
Topics: Adolescent; Adult; Cerebrospinal Fluid; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Meningeal Neoplasms; Methotrexate; Neurotoxins; Remission, Spontaneous; Time Factors | 1978 |
Non-Hodgkin's lymphomas in children. II. Treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Doxorubicin; Humans; Immunologic Factors; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Prednisolone; Prednisone; Prognosis; Remission Induction; Survival Rate; Vincristine | 1992 |
Current pharmacological treatment approaches to central nervous system leukaemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Evaluation; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Methotrexate | 1991 |
Retrospective analysis of late intensification therapy with high-dose methotrexate for standard-risk acute lymphoblastic leukemia in childhood (CCLSG-S811 study). The Children's Cancer and Leukemia Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Humans; Infant; Leucovorin; Life Tables; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Survival Rate; Vincristine | 1991 |
Prognosis of initial CNS involvement in acute lymphoblastic leukemia childhood.
Topics: Brain Neoplasms; Child; Combined Modality Therapy; Germany, East; Germany, West; Gold Radioisotopes; Humans; Life Tables; Meningeal Neoplasms; Methotrexate; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Radiography; Remission Induction; Risk; Spinal Cord Neoplasms; Survival Rate | 1990 |
The role of radiation therapy in the management of the non-Hodgkin's lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Follow-Up Studies; Humans; Leucovorin; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Methotrexate; Mycosis Fungoides; Palliative Care; Prednisone; Radiotherapy Dosage; Skin Neoplasms; Time Factors; Vincristine; Whole-Body Irradiation | 1985 |
Intensive therapy for children with acute lymphoblastic leukaemia and unfavourable presenting features. Early conclusions of study CCG-106 by the Childrens Cancer Study Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Combinations; Female; Humans; Infant; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Radiotherapy Dosage; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Central nervous system leukemia.
Topics: Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage | 1988 |
Combination intraventricular chemotherapy for meningeal neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Thiotepa; Urinary Bladder Neoplasms | 1986 |
Treatment of standard- and high-risk childhood acute lymphoblastic leukaemia with two CNS prophylaxis regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy, High-Energy; Remission Induction; Risk; Time Factors | 1987 |
Results of acute lymphoblastic leukemia therapy in childhood with a modified BFM protocol in a multicenter study in the German Democratic Republic.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Germany, East; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Prednisone; Random Allocation; Remission Induction; Risk; Thioguanine; Vincristine | 1987 |
Central nervous system (CNS) prophylaxis in children with low risk acute lymphoblastic leukemia (ALL).
Topics: Central Nervous System; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Humans; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Random Allocation | 1987 |
Long-term evaluation of a CNS prophylaxis trial--treatment comparisons and outcome after CNS relapse in childhood ALL: a report from the Childrens Cancer Study Group.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Humans; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Random Allocation; Spinal Cord Neoplasms | 1987 |
A prospective randomized trial of single-agent versus combination chemotherapy in meningeal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Drug Implants; Female; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prospective Studies; Random Allocation | 1987 |
[Acute lymphoblastic leukemia in children. Long survivals obtained with protocols C2-72 and D-74 (1972-1977)].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; BCG Vaccine; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Infant; Infant, Newborn; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisolone; Random Allocation; Testicular Neoplasms; Vincristine | 1986 |
Pediatric Oncology Group experience with modified LSA2-L2 therapy in 107 children with non-Hodgkin's lymphoma (Burkitt's lymphoma excluded).
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Marrow; Carmustine; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Mediastinal Neoplasms; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Radiotherapy Dosage; Thioguanine; Vincristine | 1985 |
Aggressive adriamycin-containing regimen (PM-FAC) in estrogen receptor-negative disseminated breast cancer. Results of a Southwest Oncology Group trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Prednisone; Receptors, Estrogen; Time Factors | 1985 |
233 other study(ies) available for methotrexate and Meningeal Neoplasms
| Article | Year |
|---|---|
Pooled Analysis of Meningioma Risk Following Treatment for Childhood Cancer.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Methotrexate; Survivors | 2022 |
Systemic absorption of intrathecal methotrexate.
Topics: Absorption, Physiological; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate | 2023 |
Small Cell Variant of Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma of the Dura Mimicking Tentorial Meningioma.
Topics: Adult; Anaplastic Lymphoma Kinase; Antineoplastic Agents; Cytarabine; Diagnosis, Differential; Etoposide; Humans; Lymphoma, Large-Cell, Anaplastic; Male; Meningeal Neoplasms; Meningioma; Methotrexate; Supratentorial Neoplasms | 2020 |
Primary leptomeningeal T-cell lymphoblastic lymphoma: a rare cause of chronic meningitis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Cranial Irradiation; Cyclophosphamide; Dexamethasone; Diagnosis, Differential; Doxorubicin; Fever; Headache; Humans; Injections, Spinal; Lymphoma, T-Cell; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meninges; Meningitis; Methotrexate; Treatment Outcome; Vincristine | 2020 |
Durable complete remission of leptomeningeal melanoma by intrathecal methotrexate maintained with systemic ipilimumab.
Topics: Adult; Dermatologic Agents; Humans; Immune Checkpoint Inhibitors; Injections, Spinal; Ipilimumab; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Treatment Outcome | 2021 |
[Three Cases of Intrathecal Chemotherapy with Ventricular Catheter for the Treatment of Leptomeningeal Metastasis from Breast Cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Delivery Systems; Humans; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate | 2018 |
Clinical outcomes of breast leptomeningeal disease treated with intrathecal trastuzumab, intrathecal chemotherapy, or whole brain radiation therapy.
Topics: Adult; Aged; Breast Neoplasms; Cranial Irradiation; Drug Therapy; Female; Hospitalization; Humans; Injections, Spinal; Karnofsky Performance Status; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies; Survival Analysis; Thiotepa; Trastuzumab; Treatment Outcome | 2019 |
Clinical features and outcome of leptomeningeal metastasis in patients with breast cancer: a single center experience.
Topics: Academic Medical Centers; Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Injections, Spinal; Medical Records; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis | 2013 |
Breast cancer leptomeningeal metastasis: the results of combined treatment and the comparison of methotrexate and liposomal cytarabine as intra-cerebrospinal fluid chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Administration Routes; Female; Humans; Injections, Spinal; Liposomes; Meningeal Neoplasms; Methotrexate; Middle Aged; Prospective Studies | 2015 |
Optimal treatment of leptomeningeal spread in glioblastoma: analysis of risk factors and outcome.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Prognosis; Retrospective Studies; Risk Factors; Salvage Therapy | 2015 |
Salvage Treatment with Intracerebrospinal Fluid Thiotepa in Patients with Leptomeningeal Metastasis After Failure of Methotrexate-based Treatment.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate; Thiotepa | 2015 |
Treatment of pediatric acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Blast Crisis; Child; Child, Preschool; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Risk Factors | 2008 |
Intrathecal trastuzumab (Herceptin) and methotrexate for meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer: a case report.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Enzyme-Linked Immunosorbent Assay; Female; Genes, erbB-2; Humans; Immunotherapy; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Middle Aged; Trastuzumab | 2008 |
Prostate-specific antigen in the cerebrospinal fluid: a marker of local disease.
Topics: Aged; Antimetabolites, Antineoplastic; Cerebrospinal Fluid; Fatal Outcome; Humans; Male; Meningeal Neoplasms; Methotrexate; Prostate-Specific Antigen; Prostatic Neoplasms | 2009 |
Heart-shaped lesion secondary to neurosarcoidosis.
Topics: Adult; Anti-Inflammatory Agents; Biopsy; Brain; Brain Diseases; Diagnosis, Differential; Dura Mater; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Methotrexate; Prednisone; Sarcoidosis; Treatment Outcome | 2008 |
First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.
Topics: Adult; Antibiotics, Antineoplastic; Antigens, Tumor-Associated, Carbohydrate; Brain Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Idoxuridine; Injections, Spinal; Iodine Radioisotopes; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Pancreatic Neoplasms; Radiopharmaceuticals | 2008 |
Leptomeningeal metastasis from ovarian carcinoma successfully treated by the intraventricular administration of methotrexate.
Topics: Antimetabolites, Antineoplastic; Female; Gadolinium; Humans; Injections, Intraventricular; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Middle Aged; Ovarian Neoplasms | 2008 |
Clinical improvement and survival in breast cancer leptomeningeal metastasis correlate with the cytologic response to intrathecal chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Cerebrospinal Fluid; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prognosis; Retrospective Studies; Survival Analysis | 2009 |
[Survival of breast cancers patients with meningeal carcinoma].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Female; Humans; Leucovorin; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate; Methylprednisolone; Middle Aged; Neuroprotective Agents; Retrospective Studies; Vitamin B Complex | 2011 |
Treatment of leptomeningeal spread of NSCLC: a continuing challenge.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cytarabine; ErbB Receptors; Erlotinib Hydrochloride; Glutamates; Guanine; Humans; Meningeal Neoplasms; Methotrexate; Mutation; Pemetrexed; Quinazolines; Radiation Dosage | 2012 |
[Intrathecal methotrexate chemotherapy for leptomeningeal carcinomatosis].
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Humans; Injections, Spinal; Lung Neoplasms; Meningeal Carcinomatosis; Meningeal Neoplasms; Methotrexate; Prognosis; Quality of Life | 2012 |
Complete radiologic response and long-term survival with use of systemic high-dose methotrexate for breast cancer-associated leptomeningeal disease.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma, Lobular; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiography; Remission Induction; Survivors | 2012 |
Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clarithromycin; Cranial Irradiation; Cyclophosphamide; Disease Progression; Etoposide; Humans; Immunophenotyping; Immunosuppressive Agents; Injections, Spinal; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Methotrexate; Methylprednisolone Hemisuccinate; Orbital Neoplasms; Prednisolone; Remission Induction; Rituximab; Vincristine | 2013 |
Successful treatment of extracranially metastasized pineal gland germinoma with high-dose methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Disease-Free Survival; Female; Germinoma; Humans; Infusions, Intravenous; Meningeal Neoplasms; Methotrexate; Neoplasm Staging; Pinealoma; Treatment Outcome | 2002 |
Unusual sites of involvement in non-Hodgkin's lymphoma: Case 2. Isolated meningeal anaplastic large-cell lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Immunohistochemistry; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Vincristine | 2002 |
Combined-modality treatment of leptomeningeal gliomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease Progression; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Survival Rate; Treatment Outcome; Triethylenephosphoramide | 2003 |
Generation of dendritic cells from the ventricular fluid in patients with meningeal carcinomatosis.
Topics: Body Fluids; Cell Differentiation; Cells, Cultured; Cerebral Ventricles; Cytarabine; Dendritic Cells; Humans; Injections, Spinal; Interleukin-12; Interleukin-12 Subunit p40; Lymphocyte Culture Test, Mixed; Meningeal Neoplasms; Methotrexate; Protein Subunits; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2003 |
THE PROPHYLAXIS OF MENINGEAL LEUKEMIA WITH INTRATHECAL METHOTREXATE.
Topics: Biomedical Research; Brain Neoplasms; Child; Humans; Injections; Injections, Spinal; Leukemia; Meningeal Neoplasms; Meninges; Methotrexate; Preventive Medicine | 1964 |
Patients presenting with CNS lesions. Case 1. Primary low-grade mucosa-associated B-cell lymphoma of the dura.
Topics: Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diagnosis, Differential; Dura Mater; Female; Headache; Humans; Immunohistochemistry; Lymphoma, B-Cell, Marginal Zone; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Seizures; Tomography, X-Ray Computed | 2003 |
Encouraging result of tamoxifen in a retinoblastoma patient with central nervous system metastasis.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Eye Enucleation; Eye Neoplasms; Female; Glucocorticoids; Humans; Meningeal Neoplasms; Methotrexate; Retinoblastoma; Skull Neoplasms; Tamoxifen; Vincristine | 2003 |
[Successful recovery of an acute myelogenous leukemia patient from a coma possibly due to leukoencephalopathy].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Coma; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Prednisolone | 2003 |
Comparison of intrathecal chemotherapy for leptomeningeal carcinomatosis of a solid tumor: methotrexate alone versus methotrexate in combination with cytosine arabinoside and hydrocortisone.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cytarabine; Drug Administration Schedule; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies; Survival Rate | 2003 |
Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Cisplatin; Combined Modality Therapy; Disease Progression; Etoposide; Humans; Ifosfamide; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Rhabdoid Tumor; Teratoma | 2004 |
[Multiple myeloma of the IgD-lambda type invading CNS].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Immunoglobulin D; Injections, Spinal; Interferon-alpha; Melphalan; Meningeal Neoplasms; Methotrexate; Middle Aged; Multiple Myeloma; Myeloma Proteins; Neoplasm Invasiveness; Nitrosourea Compounds; Prednisolone; Radiotherapy, Adjuvant; Thalidomide; Vincristine | 2004 |
[Carcinomatous meningitis from urothelial carcinoma of bladder and ureter: case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Doxorubicin; Humans; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Nephrectomy; Ureter; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine | 2004 |
Intrathecal chemotherapy for patients with meningeal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Humans; Injections, Spinal; Lung Neoplasms; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisolone; Survival Rate; Treatment Outcome | 2005 |
[Clinical evaluation of meningeal carcinomatosis associated with primary lung cancer].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Brain Neoplasms; Carcinoma, Small Cell; Gadolinium DTPA; Humans; Infusion Pumps; Lung Neoplasms; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies | 2005 |
Primary intracranial dural lymphoma of mucosa-associated lymphoid tissue (MALT) type: report of one case and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Dura Mater; Female; Humans; Hydrocortisone; Lymphoma, B-Cell, Marginal Zone; Meningeal Neoplasms; Methotrexate | 2005 |
[Retrospective study of a series of 26 carcinomatous meningitis secondary to lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cerebrospinal Fluid; Cohort Studies; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Retrospective Studies | 2005 |
[Improved quality of life in a patient with carcinomatous meningitis from invasive lobular carcinoma treated with intrathecal MTX and Ara-C in combination with systemic docetaxel].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Lobular; Cerebrospinal Fluid; Cytarabine; Docetaxel; Drug Administration Schedule; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Meningitis; Methotrexate; Quality of Life; Taxoids | 2005 |
Pediatric primary leptomeningeal lymphoma treated without cranial radiotherapy.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 8; Cyclophosphamide; Cytarabine; Dexamethasone; Diplopia; Doxorubicin; Facial Paralysis; Headache; Humans; Hydrocortisone; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Prednisolone; Remission Induction; Translocation, Genetic; Vincristine | 2007 |
Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Receptor, ErbB-2; Trastuzumab | 2006 |
Concurrent radiotherapy and capecitabine, followed by high-dose methotrexate consolidation, provided effective palliation in a patient with leptomeningeal metastases from breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Humans; Meningeal Neoplasms; Methotrexate; Palliative Care | 2007 |
[Case of leptomeningeal carcinomatosis effectively treated with intrathecal chemotherapy using ventriculoperitoneal shunt].
Topics: Adenocarcinoma, Papillary; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fatal Outcome; Humans; Injections, Spinal; Intracranial Hypertension; Male; Meningeal Neoplasms; Methotrexate; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome; Ventriculoperitoneal Shunt | 2006 |
[Meningeal carcinomatosis].
Topics: Adult; Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Carcinoma; Diagnosis, Differential; Female; Gadolinium; Humans; Hydrocephalus; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Prognosis; Sensitivity and Specificity; Spinal Puncture; Tomography, X-Ray Computed | 2006 |
[A case of meningeal carcinomatosis from lung cancer successfully treated with aggressive multimodal therapy].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Humans; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate | 2007 |
What is the best salvage therapy for treatment of isolated CNS relapse in elderly patients with imatinib-responsive Ph(+) ALL?
Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Cytarabine; Humans; Hydrocortisone; Imatinib Mesylate; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Radiotherapy; Salvage Therapy | 2007 |
Comparison of three methods of central-nervous-system prophylaxis in childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Child; Child, Preschool; Hodgkin Disease; Humans; Infant; Infusions, Parenteral; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Retrospective Studies; Risk | 1980 |
The"real stuff" for intrathecal injection during leukaemia therapy.
Topics: Cerebrospinal Fluid; Cytarabine; Humans; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate | 1982 |
Seizures in childhood lymphoblastic leukaemia patients.
Topics: Central Nervous System; Child; Epilepsy; Follow-Up Studies; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Radiography; Retrospective Studies | 1984 |
[Experiences in meningeal leukemia prevention in acute juvenile leukemia].
Topics: Child; Cobalt Radioisotopes; Gold Radioisotopes; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate | 1981 |
Treatment for meningeal carcinomatosis in breast cancer.
Topics: Brain; Breast Neoplasms; Carcinoma; Female; Humans; Injections, Intraventricular; Injections, Spinal; Leucovorin; Meningeal Neoplasms; Methotrexate; Palliative Care; Prognosis; Quality of Life | 1982 |
Improved prognosis of diffuse histiocytic and undifferentiated lymphoma by use of high dose methotrexate alternating with standard agents (M-BACOD).
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Vincristine | 1983 |
Cranial computertomography in children with acute lymphatic leukemia (ALL) and non Hodgkin-lymphoma (NHL) after different methods of CNS-treatment.
Topics: Adolescent; Brain; Child; Child, Preschool; Cobalt Radioisotopes; Combined Modality Therapy; Female; Gold Colloid, Radioactive; Humans; Injections, Spinal; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Radioisotope Teletherapy; Tomography, X-Ray Computed | 1983 |
Meningeal carcinomatosis in small cell carcinoma of the lung.
Topics: Adult; Aged; Carcinoma, Small Cell; Cytarabine; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1981 |
[Cessation of treatment in childhood acute lymphatic leukemia. Long-term observations after meningosis prevention with intrathecal gold colloid radioisotopes and methotrexate].
Topics: Adolescent; Child; Child, Preschool; Female; Gold Colloid, Radioactive; Humans; Infant; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Time Factors | 1981 |
Meningosis prophylaxis with intrathecal 198Au-colloid and methotrexate in childhood acute lymphocytic leukemia.
Topics: Bone Neoplasms; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gold Colloid, Radioactive; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Prognosis | 1982 |
[Prevention of central nervous system involvement with intrathecal 198Au colloid and methotrexate in non-Hodgkin lymphoma, acute non-lymphatic leukaemia and Ewing's sarcoma].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Female; Gold Colloid, Radioactive; Humans; Infant; Injections, Spinal; Leukemia; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Sarcoma, Ewing | 1982 |
Intrathecal therapy with 198Au-colloid for meningosis prophylaxis.
Topics: Acute Disease; Animals; Child; Child, Preschool; Combined Modality Therapy; Dogs; Dose-Response Relationship, Radiation; Gold Colloid, Radioactive; Humans; Injections, Spinal; Leukemia; Meningeal Neoplasms; Meninges; Methotrexate; Rabbits; Radiotherapy Dosage | 1984 |
[Intrathecal methotrexate therapy: improved effectiveness through high-dosage intralumbar administration?].
Topics: Adult; Child; Drug Evaluation; Humans; Injections, Spinal; Leukemia; Lumbosacral Region; Meningeal Neoplasms; Methotrexate | 1983 |
[Central nervous system irradiation for children with leukemia].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage; Radiotherapy, High-Energy; Skull; Spinal Cord | 1984 |
Pharmacokinetics of intraventricular administration.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Cisplatin; Haplorhini; Humans; Injections, Intraventricular; Kinetics; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Models, Biological | 1983 |
[Pharmacokinetics of intrathecal chemotherapy and clinical problems].
Topics: Acute Disease; Blood-Brain Barrier; Cytarabine; Humans; Infusions, Parenteral; Injections, Spinal; Kinetics; Leukemia; Meningeal Neoplasms; Methotrexate; Thiotepa | 1984 |
[Acute leukemia].
Topics: Acute Disease; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Japan; Kinetics; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Prednisone; Vincristine | 1984 |
Hodgkin's disease with leptomeningeal involvement. Report of a case with long survival.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arachnoid; Brain; Cerebrospinal Fluid; Hodgkin Disease; Humans; Injections, Spinal; Lymph Nodes; Male; Meningeal Neoplasms; Methotrexate; Pia Mater | 1984 |
[Leptomeningeal carcinomatous metastases].
Topics: Adenocarcinoma; Breast Neoplasms; Cerebrospinal Fluid; Combined Modality Therapy; Humans; Injections, Spinal; Lung Neoplasms; Meningeal Neoplasms; Methotrexate | 1984 |
History of intrathecal prophylaxis and therapy of meningeal leukemia.
Topics: Animals; Child; Cytarabine; Humans; Injections, Spinal; Kinetics; Leukemia; Meningeal Neoplasms; Methotrexate | 1983 |
Neuropsychological study in patients with ALL. Two different CNS prevention therapies--cranial irradiation plus IT methotrexate vs. IT methotrexate alone.
Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Intelligence Tests; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms; Psychomotor Performance; Skull; Tomography, X-Ray Computed | 1983 |
[Efficacy and toxicity of preventive treatment with cranial irradiation and intrathecal methotrexate on the central nervous system in childhood lymphoblastic leukemia].
Topics: Adolescent; Child; Child, Preschool; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Radiotherapy; Radiotherapy Dosage | 1983 |
Treatment of childhood acute lymphoblastic leukemia in Malaysia, 1976-1982.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisolone; Prognosis; Vincristine | 1983 |
Second central nervous system prophylaxis in children with acute lymphoblastic leukemia who relapse after elective cessation of therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Time Factors | 1983 |
[Chemotherapy for experimental subarachnoid dissemination model of brain tumor].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Injections, Intraperitoneal; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Picibanil; Rats; Rats, Inbred Strains | 1984 |
Treatment of meningeal relapse in childhood acute lymphoblastic leukemia. I. Results of craniospinal irradiation.
Topics: Acute Disease; Bone Marrow Diseases; Child; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Immune Tolerance; Infant; Injections, Spinal; Intelligence Tests; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methods; Methotrexate; Recurrence | 1984 |
[Prophylactic central nervous system irradiation for childhood acute lymphoblastic leukemia].
Topics: Adolescent; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage; Risk; Skull; Spinal Cord | 1984 |
An adult case of chronic myelogenous leukemia with myeloblastic involvement of the central nervous system.
Topics: Adult; Candidiasis; Central Nervous System Diseases; Female; Humans; Injections, Spinal; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate | 1984 |
[A case of development of neuroleukemia in the beginning of the terminal stage of chronic myeloleukosis].
Topics: Adult; Humans; Injections, Spinal; Leukemia, Myeloid; Male; Meningeal Neoplasms; Methotrexate; Terminal Care | 1984 |
[Use of Ommaya reservoirs in the treatment of meningeal relapse of acute lymphoblastic leukemia].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Injections, Intraventricular; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Meningitis; Methotrexate | 1984 |
[Prognosis of acute lymphatic leukemia in children].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Humans; Injections, Intraventricular; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Prognosis | 1984 |
Vascular changes of methotrexate-related disseminated necrotizing leukoencephalopathy.
Topics: Adult; Arteries; Axons; Brain; Child; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukoencephalopathy, Progressive Multifocal; Male; Meningeal Neoplasms; Methotrexate; Necrosis; Veins | 1984 |
Computed tomography of the brain following prophylactic treatment with irradiation therapy and intraspinal methotrexate in children with acute lymphoblastic leukemia.
Topics: Adolescent; Brain; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy; Tomography, X-Ray Computed | 1984 |
Serum and cerebrospinal fluid distribution of 5-methyltetrahydrofolate after intravenous calcium leucovorin and intra-Ommaya methotrexate administration in patients with meningeal carcinomatosis.
Topics: Aged; Carcinoma; Female; Humans; Injections, Intravenous; Injections, Intraventricular; Leucovorin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Tetrahydrofolates; Time Factors | 1983 |
Intraventricular methotrexate therapy of leptomeningeal metastasis from breast carcinoma.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Methotrexate; Middle Aged | 1983 |
A case of carcinomatous meningitis with papilledema as the only symptom: favorable response to intrathecal chemotherapy.
Topics: Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged; Papilledema | 1983 |
[Treatment and prognosis of nervous system lesions in lymphosarcoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis; Spinal Cord Neoplasms | 1983 |
Central nervous system involvement in American Burkitt's lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Burkitt Lymphoma; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Prognosis; United States | 1983 |
Successful treatment of leptomeningeal relapse of epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Implants; Female; Humans; Laparotomy; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Radiotherapy | 1984 |
[Primary lymphoma of the peripheral and central nervous system].
Topics: Adult; Brain Neoplasms; Female; Humans; Lymphoma; Meningeal Neoplasms; Meningitis, Aseptic; Methotrexate; Neoplasms, Multiple Primary; Peripheral Nervous System Neoplasms; Polyradiculopathy | 1984 |
Leptomeningeal lymphoma: perspectives on management.
Topics: Antineoplastic Agents; Arachnoid; Cytarabine; Humans; Injections, Spinal; Lymphoma; Meningeal Neoplasms; Methotrexate; Pia Mater; Thiotepa | 1981 |
Intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.
Topics: Adolescent; Antineoplastic Agents; Cerebellar Neoplasms; Child; Cytarabine; Drug Therapy, Combination; Humans; Injections, Spinal; Medulloblastoma; Meningeal Neoplasms; Methotrexate; Thiotepa | 1981 |
CSF infections complicating the management of neoplastic meningitis. Clinical features and results of therapy.
Topics: Adult; Breast Neoplasms; Catheters, Indwelling; Cerebral Ventricles; Cerebrospinal Fluid; Female; Humans; Leukemia, Lymphoid; Lung Neoplasms; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Staphylococcal Infections; Testicular Neoplasms; Thiotepa | 1982 |
Cerebrospinal fluid flow abnormalities in patients with neoplastic meningitis. An evaluation using 111indium-DTPA ventriculography.
Topics: Cerebral Ventriculography; Cerebrospinal Fluid; Humans; Indium; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Myelography; Pentetic Acid; Radioisotopes; Thiotepa; Tomography, X-Ray Computed | 1982 |
Meningeal leukemia complicating chronic lymphocytic leukemia.
Topics: Aged; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1981 |
Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients.
Topics: Adult; Aged; Antineoplastic Agents; Arachnoid; Carcinoembryonic Antigen; Cranial Nerves; Drug Administration Schedule; Female; Glucuronidase; Humans; Injections, Intraventricular; Injections, Spinal; L-Lactate Dehydrogenase; Lactates; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Pia Mater; Prognosis; Spinal Cord | 1982 |
Necrotising leucoencephalopathy associated with intrathecal/intraventricular methotrexate therapy.
Topics: Adolescent; Adult; Brain; Brain Diseases; Female; Humans; Injections, Intraventricular; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Necrosis | 1982 |
Nursing management of the patient with meningeal carcinomatosis.
Topics: Carcinoma; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate | 1980 |
[Serial EEG-examinations in children undergoing chemotherapy of ALL according to the Berlin-West-protocol (author's transl)].
Topics: Adolescent; Asparaginase; Berlin; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Electroencephalography; Germany, West; Humans; Infant; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisone; Registries; Vincristine | 1980 |
[Treatment of acute lymphoblastic leukaemia in children over twenty years (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Humans; Infant; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisone; Testicular Neoplasms; Vincristine | 1981 |
[Changes in the meningogram during amethopterin treatment of meningosis leucaemica].
Topics: Cerebrospinal Fluid; Child; Humans; Leukemia, Lymphoid; Lymphocytes; Meningeal Neoplasms; Methotrexate | 1981 |
[Clinical application of Ommaya reservoir for adult central nervous system leukemia (author's transl)].
Topics: Adolescent; Adult; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Nimustine; Nitrosourea Compounds | 1981 |
[Leukoencephalopathy in childhood leukemia (author's transl)].
Topics: Adolescent; Brain Diseases; Central Nervous System; Child; Child, Preschool; Female; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy | 1981 |
[Therapeutic methods for meningitis in acute lymphoblastic leukemia and Hodgkin's lymphoma].
Topics: Brain; Hodgkin Disease; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Meningitis; Methotrexate | 1981 |
Pharmacokinetics of methotrexate following intravenous and intraventricular administration in acute lymphocytic leukemia and non-Hodgkin's lymphoma.
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Half-Life; Humans; Infant; Injections, Intravenous; Injections, Intraventricular; Kinetics; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Nervous System Neoplasms | 1982 |
Immediate and long-term posttherapy neuropsychologic performance in children with acute lymphoblastic leukemia treated without central nervous system radiation.
Topics: Adolescent; Antineoplastic Agents; Bender-Gestalt Test; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Rhabdomyosarcoma; Stanford-Binet Test; Time Factors; Wechsler Scales | 1982 |
Adult acute lymphoblastic leukemia. Response to therapy according to presenting features in 62 patients.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Vincristine | 1982 |
[Results of 2 protocols in the treatment of acute lymphoid leukemia in children, according to prognostic factors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; BCG Vaccine; Child; Combined Modality Therapy; Doxorubicin; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Vincristine; Vindesine | 1982 |
Meningeal carcinomatosis.
Topics: Adrenal Cortex Hormones; Carcinoma; Female; Humans; Leucovorin; Meningeal Neoplasms; Methotrexate; Outcome and Process Assessment, Health Care; Radiotherapy; Time Factors | 1981 |
The use of subcutaneous cerebrospinal fluid reservoirs for the prevention and treatment of meningeal relapse of acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Cerebral Ventricles; Cerebrospinal Fluid; Child; Cytarabine; Dexamethasone; Drainage; Drug Therapy, Combination; Humans; Infant; Leucovorin; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Skull | 1982 |
Sterilization of Ommaya reservoir by instillation of vancomycin.
Topics: Adult; Catheters, Indwelling; Cerebral Ventricles; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Methotrexate; Staphylococcal Infections; Sterilization; Vancomycin | 1981 |
[Radioisotope ventriculography for functional evaluation of the Ommaya Reservoir (author's transl)].
Topics: Cerebral Ventricles; Humans; Injections, Intraventricular; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Radioisotopes; Radionuclide Imaging; Ytterbium | 1980 |
[Intraventricular chemotherapy for treatment of meningeal dissemination from malignant neoplasms (author's transl)].
Topics: Antineoplastic Agents; Cytarabine; Hydrocortisone; Injections, Intraventricular; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness | 1980 |
The influence of preoperative administration of methotrexate on the outgrowth of meningiomas and astrocytomas in tissue culture.
Topics: Astrocytoma; Brain Neoplasms; Culture Techniques; Humans; Meningeal Neoplasms; Meningioma; Methotrexate | 1980 |
Osteosarcoma following radiation treatment for meningioma: report of a case and effective treatment with chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Cisplatin; Dactinomycin; Etoposide; Female; Gonadotropin-Releasing Hormone; Humans; Ifosfamide; Lung Neoplasms; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Osteosarcoma; Tamoxifen; Tomography, X-Ray Computed; Vincristine | 1994 |
Neurologic complications of Merkel cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Merkel Cell; Cytarabine; Fatal Outcome; Humans; Leucovorin; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Nervous System Diseases; Skin Neoplasms | 1994 |
Cerebral subarachnoid sampling of cerebrospinal fluid in the rhesus monkey.
Topics: Animals; Catheterization; Cerebral Ventricles; Infusions, Parenteral; Injections, Intraventricular; Injections, Spinal; Macaca mulatta; Male; Meningeal Neoplasms; Methotrexate; Subarachnoid Space | 1994 |
Ophthalmoparesis due to Burkitt's lymphoma following cardiac transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Heart Transplantation; Humans; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Methylprednisolone; Middle Aged; Oculomotor Nerve Diseases | 1993 |
[Hypersalivation as a leading symptom of neoplastic meningiosis in highly malignant non-Hodgkin's lymphoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cerebrospinal Fluid; Cyclophosphamide; Cytarabine; Dexamethasone; Epirubicin; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Sialorrhea; Vincristine | 1993 |
Prognostic significance of 111indium-DTPA CSF flow studies in leptomeningeal metastases.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cerebral Ventriculography; Child; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Hydrocephalus; Indium Radioisotopes; Injections, Intraventricular; Life Tables; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Pentetic Acid; Prognosis; Radionuclide Imaging; Rheology; Survival Analysis; Thiotepa; Treatment Outcome | 1996 |
Pediatric leptomeningeal metastases: outcome following combined therapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Chemotherapy, Cancer, Regional Perfusion; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Humans; Injections, Intraventricular; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Radiotherapy Dosage; Survival Rate; Thiotepa; Treatment Outcome | 1997 |
Continuous intrathecal perfusion of methotrexate for carcinomatous meningitis with pharmacokinetic studies: two case studies.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate | 1997 |
Complications associated with intraventricular chemotherapy in patients with leptomeningeal metastases.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Catheters, Indwelling; Cerebral Ventricles; Child; Cytarabine; Drug Administration Schedule; Drug Delivery Systems; Female; Humans; Instillation, Drug; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Thiotepa | 1997 |
Prognostic significance of coexistent bulky metastatic central nervous system disease in patients with leptomeningeal metastases.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Retrospective Studies; Survival Analysis | 1997 |
111Indium-diethylenetriamine pentaacetic acid cerebrospinal fluid flow studies predict distribution of intrathecally administered chemotherapy and outcome in patients with leptomeningeal metastases.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Indium Radioisotopes; Injections, Spinal; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Pentetic Acid; Radiopharmaceuticals | 1998 |
Intraventricular chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain Diseases; Catheters, Indwelling; Cerebral Ventricles; Humans; Meningeal Neoplasms; Meningitis, Aseptic; Methotrexate; Necrosis | 1998 |
Meningeal myeloma in the absence of systemic disease, and as the initial feature of disease progression.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Disease Progression; Doxorubicin; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulin G; Immunoglobulin lambda-Chains; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Methylprednisolone; Middle Aged; Multiple Myeloma; Myeloma Proteins; Neoplasm Staging; Ribs; Vincristine | 1998 |
Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Intraventricular; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Treatment Outcome | 1999 |
Intrathecal depot cytarabine therapy: a welcome addition to a limited armamentarium.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Delayed-Action Preparations; Drug Carriers; Humans; Injections, Spinal; Liposomes; Meningeal Neoplasms; Methotrexate | 1999 |
ACNU, MTX and 5-FU penetration of rat brain tissue and tumors.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Autoradiography; Brain; Female; Fluorouracil; Meningeal Neoplasms; Methotrexate; Nimustine; Rats; Rats, Wistar; Reference Values | 1999 |
Intracranial meningioma following childhood irradiation for leukaemia.
Topics: Adult; Antimetabolites, Antineoplastic; Child, Preschool; Cranial Irradiation; Female; Humans; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tomography, X-Ray Computed | 2000 |
Multiple radiculopathy of the lower limbs in a cancer patient with meningeal carcinomatosis.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Female; Humans; Leg; Meningeal Neoplasms; Methotrexate; Middle Aged; Polyradiculopathy; Spinal Neoplasms | 2000 |
Cerebral vasculopathy and multiple infarctions in a woman with carcinomatous meningitis while on treatment with intrathecal methotrexate.
Topics: Adult; Antimetabolites, Antineoplastic; Carotid Stenosis; Fatal Outcome; Female; Humans; Infarction, Anterior Cerebral Artery; Infarction, Middle Cerebral Artery; Injections, Spinal; Magnetic Resonance Angiography; Meningeal Neoplasms; Meningitis; Methotrexate | 2000 |
Interventricular methotrexate therapy for carcinomatous meningitis due to breast cancer: a case with leukoencephalopathy.
Topics: Antimetabolites, Antineoplastic; Biopsy; Breast Neoplasms; Carcinoma; Fatal Outcome; Female; Humans; Injections, Intraventricular; Leukoencephalitis, Acute Hemorrhagic; Low Back Pain; Magnetic Resonance Imaging; Mastectomy, Radical; Meningeal Neoplasms; Methotrexate; Middle Aged; Paraplegia; Retroperitoneal Neoplasms; Tomography, X-Ray Computed | 2000 |
Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Feasibility Studies; Female; Humans; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
Gastric linitis adenocarcinoma and carcinomatous meningitis: an infrequent but aggressive association--report of four cases.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Hydrocortisone; Injections, Spinal; Linitis Plastica; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Stomach Neoplasms; Treatment Outcome | 2001 |
[Medical palliative therapy of meningiosis carcinomatosa of breast carcinoma with dissociated response in lumbar methotrexate instillation].
Topics: Adenocarcinoma; Breast Neoplasms; Female; Humans; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Palliative Care; Treatment Outcome | 2001 |
Fatal hemorrhage after radiochemotherapy for leptomeningeal dissemination of glioma: report of two cases.
Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Combined Modality Therapy; Fatal Outcome; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Radiotherapy; Subarachnoid Hemorrhage; Time Factors; Tomography, X-Ray Computed | 2002 |
Treatment of children and adolescents with localized parameningeal sarcoma: experience of the Intergroup Rhabdomyosarcoma Study Group protocols IRS-II through -IV, 1978-1997.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Protocols; Combined Modality Therapy; Cytarabine; Female; Head and Neck Neoplasms; Humans; Hydrocortisone; Infant; Infant, Newborn; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Outcome Assessment, Health Care; Prognosis; Radiation Dosage; Randomized Controlled Trials as Topic; Rhabdomyosarcoma; Survival Analysis; Treatment Outcome | 2002 |
Leptomeningeal carcinomatosis after major remission to taxane-based front-line therapy in patients with advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Disease Progression; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies; Spinal Cord Neoplasms; Taxoids; Time Factors; Treatment Outcome | 2002 |
Identification of dihydrofolate reductase in human central-nervous-system tumours.
Topics: Adenocarcinoma; Astrocytoma; Brain; Brain Chemistry; Brain Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Female; Glioblastoma; Glioma; Humans; Meningeal Neoplasms; Meningioma; Methotrexate; Neoplasm Metastasis; Tetrahydrofolate Dehydrogenase | 1978 |
Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia.
Topics: Acute Disease; Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy; Radiotherapy Dosage; Time Factors | 1978 |
Acute encephalopathy after initiation of cranial irradiation for meningeal leukaemia.
Topics: Acute Disease; Brain Diseases; Child, Preschool; Coma; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Radiotherapy | 1978 |
Cytostatic treatment of meningeal blastoses.
Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Humans; Injections, Spinal; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis | 1979 |
Preventive cranial irradiation in the treatment of acute lymphocytic leukemia in children.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy, High-Energy; Recurrence; Remission, Spontaneous; Skull | 1978 |
A peculiar brain scan pattern in necrotizing leukoencephalopathy after treatment for CNS-leukaemia.
Topics: Brain; Brain Neoplasms; Cerebral Ventricles; Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Necrosis; Radionuclide Imaging | 1979 |
Adult acute leukemia: frequency of central system involvement in long term survivors.
Topics: Adolescent; Adult; Brain Neoplasms; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Recurrence; Remission, Spontaneous; Time Factors | 1977 |
The Ommaya reservoir: newly recognized complications and recommendations for insertion and use.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Burkitt Lymphoma; Catheters, Indwelling; Humans; Infant; Injections, Intraventricular; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Seeding | 1978 |
Proliferative kinetics of the leukemic cells in meningeal leukemia.
Topics: Adult; Cell Division; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Recurrence; Remission, Spontaneous | 1978 |
Pyrimethamine in prevention of relapses of meningeal leukemia: report of two cases.
Topics: Central Nervous System; Child; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Pyrimethamine; Recurrence; Remission, Spontaneous | 1978 |
A reappraisal of the results of stopping therapy in childhood leukemia.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Central Nervous System; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Probability; Recurrence; Remission, Spontaneous; Risk; Sex Factors; Testicular Neoplasms; Time Factors | 1979 |
Methotrexate and asparaginase combination chemotherapy in refractory acute lymphoblastic leukemia of childhood.
Topics: Adolescent; Asparaginase; Bone Marrow; Child; Child, Preschool; Drug Administration Schedule; Drug Hypersensitivity; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Remission, Spontaneous | 1979 |
[Meningeosis leucaemica. Diagnosis and therapy (author's transl)].
Topics: Adolescent; Adult; Aged; Cell Count; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1979 |
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors | 1979 |
High-dose methotrexate with folinic acid in the treatment of advanced non-Hodgkin lymphoma including CNS involvement.
Topics: Adult; Drug Combinations; Female; Humans; Leucovorin; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1977 |
Current treatment of acute leukemia.
Topics: Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1978 |
[Neuroleukemia in blast leukemization of hematosarcomas].
Topics: Adolescent; Adult; Brain Neoplasms; Female; Humans; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Spinal Cord Neoplasms | 1979 |
[(Meningeal carcinomatosis in patients with breast cancer)].
Topics: Adult; Aged; Breast Neoplasms; Carmustine; Female; Humans; Injections, Spinal; Mastectomy; Meningeal Neoplasms; Methotrexate; Middle Aged | 1979 |
[Simple propositions in the treatment of acute lymphoblastic leukaemia (author's transl)].
Topics: BCG Vaccine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunotherapy; Injections, Spinal; Leukemia, Lymphoid; Long-Term Care; Lymphocytes; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Mycobacterium bovis; Prednisone; Remission, Spontaneous; Vincristine | 1977 |
Intracerebral calcifications in childhood lymphoblastic leukemia. A new iatrogenic disease?
Topics: Brain; Brain Diseases; Calcinosis; Child, Preschool; Humans; Iatrogenic Disease; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Radiotherapy | 1978 |
Clinical correlations of CT scan-detected calcifications of the basal ganglia.
Topics: Adolescent; Adult; Aged; Basal Ganglia; Brain Diseases; Calcinosis; Child; Child, Preschool; Female; Humans; Intracranial Arteriovenous Malformations; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy; Tomography, X-Ray Computed | 1979 |
Enhancement of CNS penetration of methotrexate by hyperosmolar intracarotid mannitol or carcinomatous meningitis.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Carotid Arteries; Female; Injections, Intra-Arterial; Mannitol; Meningeal Neoplasms; Methotrexate; Osmolar Concentration; Pharmaceutic Aids; Rats | 1979 |
[Preventive therapy of central nervous system leukemia in children. II. Results of CNS-prophylaxis with 2,400 rads of cranial irradiation and intrathecal injection of methotrexate and hydrocortisone (author's transl)].
Topics: Child; Child, Preschool; Humans; Hydrocortisone; Infant; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage; Skull | 1977 |
[Surface properties of cerebrospinal fluid cells following intrathecal methotrexate treatment].
Topics: Adult; Cerebrospinal Fluid; Humans; Infant; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Meningioma; Methotrexate | 1978 |
Current status of intrathecal chemotherapy for human meningeal neoplasms.
Topics: Animals; Antineoplastic Agents; Arachnoiditis; Child; Humans; Injections, Intraventricular; Injections, Spinal; Leukemia; Leukoencephalopathy, Progressive Multifocal; Meningeal Neoplasms; Methotrexate; Research Design | 1977 |
[A case of interstitial pneumonitis induced by intrathecal injection of methotrexate (author's transl)].
Topics: Female; Humans; Injections, Spinal; Lymphoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Pulmonary Fibrosis; Retroperitoneal Neoplasms | 1979 |
[Chemotherapy of acute childhood leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Female; Humans; Hydrocortisone; Infant; Infant, Newborn; Leukemia; Male; Meningeal Neoplasms; Methotrexate | 1977 |
Cerebromedullospinal disconnection after intraventricular methotrexate.
Topics: Brain Diseases; Carcinoma; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Methotrexate; Middle Aged; Paraplegia; Syndrome | 1978 |
Meningeal carcinomatosis in breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Hyperventilation as the initial manifestation of lymphomatous meningitis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Anxiety Disorders; Cyclophosphamide; Doxorubicin; Facial Paralysis; Humans; Hyperventilation; Injections, Spinal; Lymphoma, B-Cell; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Palliative Care; Prednisone; Psychophysiologic Disorders; Vincristine | 1992 |
Meningeal carcinomatosis in urothelial cancer.
Topics: Adult; Humans; Kidney Neoplasms; Male; Meningeal Neoplasms; Methotrexate | 1992 |
Diagnosis and treatment of patients with meningeal carcinomatosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Cytarabine; Female; Humans; Injections, Spinal; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies | 1992 |
[Study of meningeal carcinomatosis: diagnosis and treatment].
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Combined Modality Therapy; Electroencephalography; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Spinal Puncture; Tomography, X-Ray Computed | 1992 |
Acute reversible neurotoxicity after intrathecal low-dose methotrexate.
Topics: Acute Disease; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Nervous System Diseases | 1991 |
Pharmacologic approaches to the treatment of meningeal malignancy.
Topics: Adolescent; Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Blood-Brain Barrier; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Thiotepa | 1991 |
Brain lesions following combined treatment with methotrexate and craniospinal irradiation.
Topics: Adult; Aged; Brain Diseases; Brain Edema; Breast Neoplasms; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Demyelinating Diseases; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Male; Meningeal Neoplasms; Mental Disorders; Methotrexate; Middle Aged; Necrosis | 1991 |
Meningeal carcinomatosis in breast cancer. Prognostic factors and influence of treatment.
Topics: Adult; Aged; Breast Neoplasms; Cause of Death; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Combined Modality Therapy; Female; Glucose; Humans; Injections, Intraventricular; Lung Neoplasms; Lymphatic Metastasis; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Receptors, Estrogen; Staphylococcal Infections; Survival Rate; Tomography, X-Ray Computed | 1991 |
[Focal cerebral necrosis caused by intraventricular chemotherapy with methotrexate].
Topics: Brain; Brain Abscess; Brain Neoplasms; Cerebral Ventricles; Confusion; Diagnosis, Differential; Female; Hemiplegia; Humans; Infusion Pumps, Implantable; Leukoencephalopathy, Progressive Multifocal; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Necrosis | 1991 |
Cerebrospinal fluid tumour markers in patients treated for meningeal malignancy.
Topics: Adult; Aged; beta 2-Microglobulin; Biomarkers, Tumor; Blood Glucose; Carcinoembryonic Antigen; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Combined Modality Therapy; Cranial Irradiation; Female; Glucuronidase; Humans; L-Lactate Dehydrogenase; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Reference Values | 1991 |
Treatment of carcinomatous meningitis from transitional cell carcinoma of the bladder.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Vinblastine | 1991 |
[Ventriculo-lumbar perfusion chemotherapy with methotrexate and cytosine arabinoside for meningeal dissemination of malignant disease].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebral Ventricles; Chemotherapy, Cancer, Regional Perfusion; Cytarabine; Female; Humans; Infusion Pumps; Lumbosacral Region; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1991 |
We're "fossilized" in the optimal use of the Ommaya reservoir.
Topics: Drug Administration Schedule; Humans; Infusions, Parenteral; Meningeal Neoplasms; Methotrexate; Subarachnoid Space | 1990 |
Primary leptomeningeal B-cell lymphoma in a 8-year-old child.
Topics: Agammaglobulinemia; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Dexamethasone; DNA, Viral; Doxorubicin; Drug Therapy, Combination; Herpesvirus 4, Human; Humans; Lymphoma, B-Cell; Male; Meningeal Neoplasms; Methotrexate; Vincristine | 1990 |
Cerebrospinal fluid B2-microglobulin levels in meningeal involvement by malignancy.
Topics: Adolescent; Adult; beta 2-Microglobulin; Child; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Predictive Value of Tests; Prospective Studies | 1990 |
Transitional cell carcinomatous meningitis after M-VAC (methotrexate, vinblastine, doxorubicin, and cisplatin) chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Humans; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged; Urinary Bladder Neoplasms; Vinblastine | 1990 |
Early blindness and coma during intrathecal chemotherapy for meningeal carcinomatosis.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Blindness; Breast Neoplasms; Coma; Cytarabine; Demyelinating Diseases; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Methotrexate | 1990 |
Sudden neurologic death after intrathecal methotrexate.
Topics: Adult; Brain Death; Brain Edema; Death, Sudden; Humans; Injections, Spinal; Leukemia-Lymphoma, Adult T-Cell; Leukoencephalopathy, Progressive Multifocal; Male; Meningeal Neoplasms; Methotrexate | 1990 |
[Meningeal gliomatosis--clinical features and results of treatment].
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Child; Cytarabine; Female; Glioma; Humans; Incidence; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1989 |
MACOP-B chemotherapy for the treatment of diffuse large-cell lymphoma.
Topics: Actuarial Analysis; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Arachnoid; Bleomycin; Bone Marrow; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Humans; Inflammation; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Mucous Membrane; Neoplasm Staging; Pia Mater; Prednisone; Vincristine | 1985 |
Central nervous system involvement in haematological malignancies.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Spinal Neoplasms | 1989 |
The significance of an isolated central nervous system relapse, occurring as first relapse in children with acute lymphoblastic leukemia.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Retrospective Studies; Time Factors | 1989 |
Central nervous system (CNS) leukemia: the role of high dose cytarabine (HDAra-C).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Remission Induction | 1989 |
Pharmacokinetics of methotrexate in the cerebrospinal fluid after intracerebroventricular administration in patients with meningeal carcinomatosis and altered cerebrospinal fluid flow dynamics.
Topics: Adult; Female; Humans; Indium Radioisotopes; Injections, Intraventricular; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1989 |
Carcinomatous meningitis from transitional cell carcinoma of the bladder: case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Humans; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Pyrimidines; Urinary Bladder Neoplasms | 1989 |
[Intrathecal chemotherapy by a totally implanted device].
Topics: Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate | 1986 |
Leukaemic meningitis in chronic lymphocytic leukaemia.
Topics: Humans; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Meningitis; Methotrexate; Middle Aged | 1986 |
Convulsions and intracranial calcifications in a leukemic infant receiving only intrathecal methotrexate as central nervous system prophylaxis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Diseases; Calcinosis; Cyclophosphamide; Doxorubicin; Humans; Infant; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Seizures; Vincristine | 1987 |
Occult testicular leukemia in a patient with acute monocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Doxorubicin; Humans; Hydrocortisone; Leukemia, Monocytic, Acute; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Testicular Neoplasms; Thioguanine | 1987 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Floxuridine; Hydantoins; Leukemia, Myeloid; Liver Neoplasms, Experimental; Lomustine; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Procarbazine; Rats | 1985 |
Acute lymphoblastic leukemia in adults: results of intraventricular maintenance chemotherapy for central nervous system prophylaxis and treatment.
Topics: Adolescent; Adult; Aged; Female; Humans; Injections, Intraventricular; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Remission Induction | 1988 |
[Meningiosis neoplastica--clinical aspects and therapy. Experiences in 78 cases].
Topics: Breast Neoplasms; Combined Modality Therapy; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Melanoma; Meningeal Neoplasms; Meninges; Methotrexate; Skin Neoplasms | 1988 |
Central nervous system prophylaxis in childhood acute lymphoblastic leukaemia: CT brain appearance after 3 years continuous complete remission in 36 Malaysian children.
Topics: Brain; Child; Child, Preschool; Combined Modality Therapy; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Remission Induction; Tomography, X-Ray Computed | 1988 |
A lethal neurotoxic reaction after intraventricular methotrexate administration.
Topics: Adenocarcinoma; Autopsy; Cerebral Ventricles; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Meningeal Neoplasms; Methotrexate; Middle Aged | 1988 |
Pulsatile growth hormone secretion in children with acute lymphoblastic leukemia after 1800 cGy cranial radiation.
Topics: Adolescent; Body Height; Central Nervous System; Child; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; Growth Hormone; Humans; Male; Meningeal Neoplasms; Methotrexate; Periodicity; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1988 |
[Combination of radio-chemotherapy for curing of childhood hematologic tumors: preventive approaches and problems on CNS involvement].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis | 1988 |
Aggressive treatment improves survival in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1988 |
Short-term intensive treatment (V.A.A.P.) of adult acute lymphoblastic leukemia and lymphoblastic lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Evaluation; Female; Humans; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1988 |
Disseminated necrotizing encephalopathy induced by methotrexate therapy alone.
Topics: Brain; Brain Diseases, Metabolic; Female; Humans; Injections, Spinal; Leigh Disease; Lymphoma; Meningeal Neoplasms; Methotrexate; Middle Aged | 1988 |
Acute fever and delayed leukoencephalopathy following low dose intraventricular methotrexate.
Topics: Adult; Aged; Brain; Breast Neoplasms; Female; Fever; Humans; Injections, Intraventricular; Leukoencephalopathy, Progressive Multifocal; Meningeal Neoplasms; Methotrexate; Middle Aged | 1988 |
Whole brain irradiation and intrathecal methotrexate in the treatment of solid tumor leptomeningeal metastases--a Southwest Oncology Group study.
Topics: Combined Modality Therapy; Female; Follow-Up Studies; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Middle Aged | 1988 |
High-dose methotrexate: methotrexate and 7-hydroxymethotrexate diffusion in cerebrospinal fluid.
Topics: Adult; Half-Life; Humans; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate | 1988 |
Cerebrospinal fluid protein findings during prophylaxis and treatment of neuromeningosis in leukaemic patients.
Topics: Adult; Aged; Albumins; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; Cytarabine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1987 |
Systemic high-dose ara-C for the treatment of meningeal leukemia in adult acute lymphoblastic leukemia and non-Hodgkin's lymphoma.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1986 |
[Serum and cerebrospinal fluid levels in systemic medium-high and high dosage methotrexate therapy in pediatric neuro-oncology].
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia, Lymphoid; Medulloblastoma; Meningeal Neoplasms; Methotrexate | 1986 |
[End results and comparative analysis of treatment programs for childhood acute lymphocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Combined Modality Therapy; Humans; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Prognosis | 1987 |
[Clinical pharmacology of methotrexate (MTX)--altered central nervous system pharmacology of MTX with meningial relapse of childhood leukemia].
Topics: Child; Child, Preschool; Female; Humans; Infant; Infusions, Intravenous; Kinetics; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate | 1986 |
[Intellectual dysfunction in long-term survivor of one of identical twin with acute lymphocytic leukemia. Children's Cancer and Leukemia Study Group].
Topics: Child; Diseases in Twins; Female; Humans; Intellectual Disability; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Radiotherapy; Twins, Monozygotic | 1986 |
[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Mitoguazone; Prednisone; Thioguanine; Vincristine | 1986 |
Dihydrofolate reductase-activity in brain tissue. Effect of X-irradiation.
Topics: Animals; Brain; Folic Acid Antagonists; Humans; Leukemia, Lymphoid; Liver; Meningeal Neoplasms; Methotrexate; Rabbits; Tetrahydrofolate Dehydrogenase | 1987 |
Effect of the intermittent prophylactic treatment of the central nervous system in adults with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Brain Neoplasms; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisolone; Time Factors | 1987 |
The risks of central nervous system relapse and leukoencephalopathy in patients receiving marrow transplants for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Brain Diseases; Child; Child, Preschool; Humans; Infant; Leukemia; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Middle Aged; Recurrence; Risk | 1986 |
Is cranial radiation necessary for CNS prophylaxis in pediatric NHL?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Infant; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Remission Induction | 1987 |
Chronic lymphocytic leukemic meningitis as a cause of the syndrome of inappropriate secretion of antidiuretic hormone.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Inappropriate ADH Syndrome; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Meningitis; Methotrexate | 1987 |
Intermittent central nervous system irradiation and intrathecal chemotherapy for central nervous system leukemia in children.
Topics: Adolescent; Central Nervous System; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Infant; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local | 1987 |
Progressive loss of vision in patients with high-grade non-Hodgkin's lymphoma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Optic Neuritis; Prednisone; Vincristine | 1987 |
Combined modality therapy for adults with small noncleaved cell lymphoma (Burkitt's and non-Burkitt's types).
Topics: Abdominal Neoplasms; Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pelvic Neoplasms; Prednisone; Prognosis; Vincristine | 1986 |
Diagnosis and treatment of meningeal carcinomatosis in ten patients with breast cancer.
Topics: Adult; Brain; Breast Neoplasms; Carcinoma; Cerebrospinal Fluid; Cytarabine; Female; Humans; Meningeal Neoplasms; Methotrexate; Middle Aged; Tomography, X-Ray Computed | 1986 |
Altered central nervous system pharmacology of methotrexate in childhood leukemia: another sign of meningeal relapse.
Topics: Child; Child, Preschool; Female; Humans; Infant; Infusions, Parenteral; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Prognosis; Regression Analysis | 1985 |
Remission induction of meningeal leukemia with high-dose intravenous methotrexate.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions, Parenteral; Leukemia, Lymphoid; Leukocyte Count; Male; Meningeal Neoplasms; Methotrexate; Neutropenia; Seizures; Stomatitis | 1985 |
Therapy of CNS leukemia with intraventricular chemotherapy and low-dose neuraxis radiotherapy.
Topics: Adolescent; Brain; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Combinations; Female; Humans; Infant; Injections, Intraventricular; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage; Recurrence | 1985 |
[Method of cranial irradiation of children with leukemia].
Topics: Child, Preschool; Combined Modality Therapy; Humans; Infant; Injections, Spinal; Leukemia, Lymphoid; Meningeal Neoplasms; Methotrexate; Skull | 1985 |
Leukemic meningitis in B-cell chronic lymphocytic leukemia.
Topics: Adult; B-Lymphocytes; Humans; Injections, Spinal; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Meningitis; Methotrexate | 1985 |
Remission from central nervous system involvement in adults with acute leukemia. Effect of intensive therapy and prognostic factors.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage | 1985 |
[Case report of meningeal carcinomatosis of gastric cancer successfully treated with intrathecal and systemic chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Injections, Spinal; Meningeal Neoplasms; Methotrexate; Prednisolone; Stomach Neoplasms; Tegafur | 1985 |
Meningeal involvement in patients with acute nonlymphocytic leukemia. Incidence, management, and predictive factors.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis | 1985 |
Meningeal leukaemia.
Topics: Child; Female; Humans; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Prognosis; Recurrence | 1967 |