methotrexate has been researched along with Malignant Melanoma in 204 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 130 (63.73) | 18.7374 |
| 1990's | 25 (12.25) | 18.2507 |
| 2000's | 9 (4.41) | 29.6817 |
| 2010's | 29 (14.22) | 24.3611 |
| 2020's | 11 (5.39) | 2.80 |
| Authors | Studies |
|---|---|
| Blair, AH; Ghose, T; Kralovec, J; Mammen, M; Singh, M; Spencer, G | 1 |
| Abe, M; Abe, T; Adachi, H; Asano, N; Ito, S; Kasai, S; Matsuno, S; Mizutamari, H; Nishio, T; Onogawa, T; Satoh, F; Shimosegawa, T; Suzuki, M; Suzuki, T; Tanemoto, M; Tokui, T; Toyohara, T; Unno, M | 1 |
| Ernst, ME; Mar, VJ; Orchard, SG; Wolfe, R; Yan, MK | 1 |
| Chen, SK; Desai, RJ; Gautam, N; Glynn, RJ; He, M; Kim, SC; Lee, H; Vine, SM; Weinblatt, ME | 1 |
| Mar, VJ; Wang, C; Wluka, AE; Wolfe, R; Yan, MK | 1 |
| Gómez, LA; González Barrios, A; Riaño-Pachón, DM; Vásquez, AF | 1 |
| Konda, S; Kreher, MA; Longo, MI; Noland, MMB; Valdes-Rodriguez, R | 1 |
| Goldfarb, N; Mansh, M; Rypka, KJ | 1 |
| Gillstedt, M; Osmancevic, A; Paoli, J; Polesie, S | 4 |
| Egeberg, A; Haugaard, JH | 1 |
| De Moll, EH; Desman, G; Friedlander, P; Levitt, J; Varma, A | 1 |
| Elston, D | 1 |
| Dietrich, C; Hassel, JC; Herbst, R; Salzmann, M; Steinbrecher, A | 1 |
| Jones, G | 1 |
| Gandiga, PC; Gonzalez-Rivera, T; Sreih, AG; Wang, AR | 1 |
| Harasawa, H; Kitahara, T; Kodama, Y; Kurosaki, T; Muro, T; Nakagawa, H; Nakamura, T; Noda, R; Sasaki, H; Sato, K | 1 |
| Brady, B; McLean, C; Ostor, AJK; Rischin, A | 1 |
| Abel, I; Clasen-Linde, E; Hansen, MF | 1 |
| Galazka, P; Marjanska, A; Marjanski, M; Styczynski, J; Wysocki, M | 1 |
| Cabezas-Herrera, J; Chazarra, S; Fernández-Pérez, MP; Freter, R; Goding, CR; Middleton, M; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-Del-Campo, L | 1 |
| Cabezas-Herrera, J; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L | 1 |
| Fukami, K; Hirano, T; Kato, A; Kojima, H; Murayama, Y; Nagano, T; Okabe, T; Satow, R; Saya, H; Tamura, M | 1 |
| Merlino, G; Wilson, W | 1 |
| Clark, AH; Legler, AA; Milhem, MM; Moye, MS; Van Beek, MJ | 1 |
| Nihal, M; Wood, GS; Wu, J | 1 |
| Cervini, G; Morilla, MJ; Romero, EL; Schilrreff, P | 1 |
| Dong, L; Gao, Y; Pan, Z; Wang, Y; Yang, G; Yuan, T | 1 |
| Agathocleous, M; DeBerardinis, RJ; Hu, Z; Huddlestun, SE; Johnson, TM; Leitch, AM; Morrison, SJ; Murphy, MM; Piskounova, E; Zhao, Z | 1 |
| Barylak, M; Cendrowski, K; Drozdzik, M; Kurzawski, M; Mijowska, E; Peruzynska, M; Piotrowska, K; Roginska, D; Szelag, S; Trzeciak, K | 1 |
| Kato, Y; Yamamoto, T | 1 |
| Gillstedt, M; Osmancevic, A; Paoli, J; Polesie, S; Sönnergren, HH | 1 |
| Barber, M; Buchbinder, R; Giles, G; Hall, S; Harkness, A; Heuzenroeder, L; Jolley, D; Lewis, D; Littlejohn, G; Miller, MH; Ryan, PF; Wluka, AE | 1 |
| Kudriavtsev, DV; Kudriavtseva, GT; Mardynskiĭ, IuS | 1 |
| Cabezas-Herrera, J; Montenegro, MF; Rodríguez-López, JN; Sánchez-del-Campo, L | 1 |
| Good, LM; High, WA; Miller, MD | 1 |
| Kanelleas, A; Katoulis, AC; Panayiotides, I; Stavrianeas, NG; Zambacos, G | 1 |
| Tu, J; Von Nida, J | 1 |
| Calzavara-Pinton, P; Farisoglio, C; Manganoni, AM; Pavoni, L; Sereni, E; Zane, C | 1 |
| Capella, GL | 1 |
| Arcese, A; Camplone, G; Carlesimo, M; Di Russo, PP; Gamba, A; La Pietra, M; Mari, E; Orsini, D | 1 |
| Cabezas-Herrera, J; Chazarra, S; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L | 1 |
| Neville, F; Nystrom, ML; Oliver, RT; Shamash, J; Steele, JP | 1 |
| BELMONT, O; COHEN, EA; LEVICK, SN; STEINMETZ, CG | 1 |
| TOLMAN, MM; WILGRAM, GF | 1 |
| CONNOLLY, JM; MILLER, BJ; TALSANIA, SJ | 1 |
| JOHNSTON, ID | 1 |
| ARDAGH, JW; FOX, HW; SKELTON, CC | 1 |
| ARIEL, IM; GALEY, D; RESNICK, MI | 1 |
| BRANDKAMP, WW; MOORE, JG; VANCAMPENHOUT, JL | 1 |
| COBB, JP; WALKER, DG | 1 |
| DIPAOLO, JA; DOWD, JE; WATNE, AL | 1 |
| SULLIVAN, RD; ZUREK, WZ | 1 |
| LAWTON, RL | 1 |
| DECOSSE, JJ; ROGERS, LS | 1 |
| Barbera-Guillem, E; Macivor, M; Sampsel, JW | 1 |
| Katz, EE; Krausz, T; Rapp, DE; Sokoloff, MH; Suzue, K; Wille, MA | 1 |
| Hills, WJ; Rufino, C; Stehlin, JS | 1 |
| Bleehen, NM; Bryant, TH | 1 |
| Miller, E; Oberfield, RA; Ojima, Y; Sullivan, RD; Zurek, WZ | 1 |
| Norrell, H; Wilson, C | 1 |
| Krauss, I; Krauss, J; Lange, U; Pauer, HD | 1 |
| Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM | 1 |
| Markman, M | 1 |
| Oberfield, RA | 3 |
| Bostock, CJ; Tyler-Smith, C | 1 |
| McCormick, KJ; Merrick, RH; Panje, WR; Seltzer, S | 1 |
| Mabel, JA; Wodinsky, I | 1 |
| Wemmer, U | 1 |
| Carey, TE; Krause, CJ; Shimoura, S; Spiegel, J | 1 |
| Mathe, G | 1 |
| Bittner, H; Gläser, A | 1 |
| Gaukroger, JM; Wilson, L | 1 |
| Farid, Y; Gaukroger, J; Habeshaw, T; Harding, N; Mackie, R; Stewart, M; Wilson, L | 1 |
| Perez, DJ; Tattersall, MH | 1 |
| Adcock, RA; Bland, KI; Morris, RR; Palin, WE; Tobin, GR; von Fraunhofer, JA | 1 |
| Carson, DA; Kamatani, N; Nelson-Rees, WA | 1 |
| Francis, PR; Slowiaczek, P; Tattersall, MH; Taylor, IW | 1 |
| Banzet, P; Jacquillat, C; Maral, J | 1 |
| Hall, TC; Klimo, P; Leahy, MF; Silver, HK | 1 |
| Thiers, BH | 1 |
| Bostock, CJ; Clark, EM | 1 |
| Kennedy, DG; Murphy, RF; Van Den Berg, HW | 1 |
| Abelson, HT; Kufe, DW; Wick, MM | 1 |
| Geissler, U; Richter, P; Sarembe, B | 1 |
| Balow, JE; Brennan, MF; Brooks, AE; Collins, JM; Dedrick, RL; DeVita, VT; Hubbard, SM; Jones, RB; Myers, CE | 1 |
| Dufour, FD; Mah, SG; Morton, DL; Okada, GT | 1 |
| Algermissen, B; Czarnetzki, BM; Kohlmus, CM; Schadendorf, D; Worm, M | 1 |
| Eichfeld, U; Gläser, A; Kraus, J; Pauer, HJ; Schneider, G; Schwarz, I | 1 |
| Chandrasekaran, B; Duch, DS; Kute, TE | 1 |
| Korovin, SI; Naleskina, LA; Tolstopiatov, BA | 1 |
| Korovin, SI; Tolstopiatov, BA | 2 |
| De Traversay, J; Jean, Y; Lemieux, P | 1 |
| Rofstad, EK; Sanna, K | 1 |
| Bloch, DA; Brown, DM; Kitchell, BE; Luck, EE; Orenberg, EK; Woods, LL | 1 |
| Goupille, P; Jeannou, J; Valat, JP | 1 |
| Korovin, SI | 1 |
| Hardwick, N; Mulherin, D; Potter, T | 1 |
| Chamberlain, MC; Cole, BF; Glantz, MJ; Howell, SB; Jaeckle, KA; LaFollette, S; Maria, B; Phuphanich, S; Recht, L; Schumann, GB; Swinnen, LJ | 1 |
| Anuszewska, EL; Koziorowska, JH | 1 |
| Bani, MR; Ben-David, Y; Chu, W; Kapoor, M; Kerbel, RS; Lu, SJ; Pak, BJ; Tamir, A | 1 |
| Pletnev, SD | 1 |
| Dimopoulos, J; Hollmann, K; Kühböck, J | 1 |
| Cohen, SC; Gabelnick, HL; Goldin, A; Johnson, RK | 1 |
| Frei, E; Krishan, A; Paika, KD; Pitman, SW; Smith, DC; Tattersall, HN | 1 |
| Steigleder, GK | 1 |
| Cattan, A; Coninx, P; Kalis, B; Liautaud, F; Pourny, C | 1 |
| Boccardo, F; Musso, M; Porcile, G; Rosso, R; Santi, L | 1 |
| Engelhardt, P; Lorenz, R | 1 |
| Doppman, JL; Dunnick, NR; Jones, RB; Myers, CE; Speyer, J | 1 |
| Banzet, P; Belaich, S; Chastang, C; Civatte, J; Cottenot, F; Israel, L; Jacquillat, C; Maral, J; Puissant, A | 1 |
| Rosenberg, SA | 1 |
| Bertino, JR | 1 |
| Carlson, M; Karakousis, CP | 1 |
| Chabner, BA; Fisher, RI; Myers, CE | 1 |
| Hughes, LE; Jones, KD | 1 |
| Bostock, CJ; Clark, EM; Harding, NG; Mounts, PM; Tyler-Smith, C; van Heyningen, V; Walker, PM | 1 |
| Gerzeli, G; Marini, G; Nano, R | 1 |
| Eilber, FR; Morton, DL; Roth, JA | 1 |
| Block, JB; Drakes, TP; Isacoff, W; Tabbarah, H | 1 |
| Gang, M; Garibjanian, BT; Goldin, A; Johnson, RK; Kline, I; Vadlamudi, S; Venditti, JM | 1 |
| Berry, RJ; Laing, AH; Wells, J | 1 |
| Iavorskiĭ, VV; Kadagidze, ZG; Kupin, VI; Malaev, SG; Trapeznikov, NN | 1 |
| Brown, AS; Hamilton, RW; Horstmann, JT; Johnson, JL; Rosato, FE; Wallack, MK | 1 |
| Morton, DL; Ramming, KP; Silver, HK; Sparks, FC; Wile, AG; Wolk, RW | 1 |
| Young, RC | 1 |
| Golomb, FM | 1 |
| Block, JB; Eiber, FR; Forster, T; Isacoff, WH; Morton, DL; Townsend, CM | 1 |
| Armstrong, DM; Aust, JB; Cruz, AB; Dowell, KE | 1 |
| Kadagidze, ZG; Kupin, VI; Radzikhovskaia, RM; Trapeznikov, NN | 1 |
| Asselbergs, FA; van Meerwijk, J; van Someren, P | 1 |
| Hayakawa, T; Izumoto, S; Kubo, S; Murasawa, A; Nakagawa, H; Nakajima, S; Nakajima, Y | 1 |
| Gillies, SD; Lo, KM | 1 |
| Musk, P; Parsons, PG; Stowers, A | 1 |
| Ghose, T; Om, A; Rowden, G | 1 |
| Foldvari, M; Mezei, C; Mezei, M | 1 |
| Blair, AH; Ferrone, S; Ghose, T; Kralovec, Y; Mammen, M; Singh, M; Temponi, M | 1 |
| Hart, IR; Kalebic, T; McMillan, TJ; Stark, GR | 1 |
| Ng, TB; Tsao, SW; Yeung, HW | 1 |
| Babich, H; Borenfreund, E; Martin-Alguacil, N | 1 |
| Barth, V; Schönfelder, M | 1 |
| Barnhill, RL; Wiles, JC | 1 |
| Beidler, D; Dillman, RO; Johnson, DE; Ogden, J | 1 |
| Wang, QL | 1 |
| Hellthaler, G; Krause, G; Krauss, J | 1 |
| Barth, A; Burchardt, U; Franke, M; Krauss, J | 1 |
| Dreller, E | 1 |
| Giannone, L; Greco, FA; Hainsworth, JD | 1 |
| Endo, N; Hara, T; Kato, Y; Kishida, K; Saito, M; Takeda, Y; Umemoto, N | 1 |
| Poburski, R; Wiehler, S | 1 |
| Faulkner, G; Ghose, TI; Mezei, M; Singh, M | 1 |
| Bostík, J; Bures, L; Spundová, M | 1 |
| Vítek, JA | 1 |
| Cillo, C; Dick, JE; Hill, RP; Ling, V | 1 |
| Endo, N; Hara, T; Kato, Y; Takeda, Y; Umemoto, N | 1 |
| Hönigsmann, H; Ortel, B; Tanew, A; Wolff, K; Zussner, C | 1 |
| Blair, AH; Ferrone, S; Ghose, T; Uadia, P | 1 |
| Blair, AH; Ferrone, S; Ghose, T; Goundalkar, A; Kulkarni, PN; Mezei, M; Uadia, P | 1 |
| Patchell, RA; Posner, JB | 1 |
| Aron-Rosa, D; Auclerc, G; Dhermy, P; Jacquillat, C; Maral, J; Sellami, M; Weil, M | 1 |
| Gary-Bobo, J | 1 |
| Richard, JM; Sancho, H | 1 |
| McDonald, CJ | 1 |
| Falkson, G | 1 |
| Anderson, J; Helman, P; Malherbe, E; Sealy, R | 1 |
| Cunningham, TJ; Horton, J; Laffin, R; Olson, KB; Sullivan, J | 1 |
| Hollander, A | 1 |
| Adamson, RH; Henderson, ES; Oliverio, VT | 1 |
| Brunat, M; Dargent, M; Pommatau, E | 1 |
| Watt, J | 1 |
| Coltman, CA; Costanzi, JJ | 1 |
| Bilder, J; Hornová, J | 1 |
| Foley, JF; Lemon, HM; Miller, D | 1 |
| Chernik, NL; Olson, ME; Posner, JB | 2 |
| Hockly, J; Sealy, A; Shepstone, B | 1 |
| Freckman, HA | 1 |
| McCullough, JL; Weinstein, GD | 1 |
| Hill, GJ; Larsen, RR | 1 |
| Averbukh, LA; Bazhanov, VS; Grinshteĭn, AM; Lepeshkina, GN; Shorin, VA | 1 |
| Gordon, JA | 1 |
| Heenan, PJ; Wright, JL | 1 |
| Mattern, J; Volm, M; Wayss, K | 1 |
| Amiel, JL; Cattan, A; de Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Rosenfeld, C; Schlumberger, JR; Schneider, M; Schwarzenberg, L | 1 |
| Kokame, GM; Krementz, ET | 1 |
| Mahaley, MS; Woodhall, B | 1 |
| Derriks, R; Heynen, E; Mannes, P; Moens, R | 1 |
| Couture, J; Deschênes, L | 1 |
| Banzet, P; Dufourmentel, C; Pailheret, JP | 1 |
| Mills, EE | 1 |
| Artz, CP; O'Brien, PH | 1 |
| Hanham, IW; Newton, KA; Westbury, G | 1 |
| Ariel, IM; Pack, GT | 1 |
| Klein, E | 1 |
| Sano, K; Terao, H; Yoshimatsu, N | 1 |
| Friedell, GH; Robinson, CR; Sommers, SC | 1 |
| Gorgun, B; Watne, AL | 1 |
| Reeves, E; Reeves, G; Sommers, SC | 1 |
10 review(s) available for methotrexate and Malignant Melanoma
| Article | Year |
|---|---|
Association Between Low-Dose Methotrexate Exposure and Melanoma: A Systematic Review and Meta-analysis.
Topics: Arthritis, Rheumatoid; Humans; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Psoriasis | 2022 |
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: Methotrexate, alkylating agents, biologics, and small molecule inhibitors.
Topics: Alkylating Agents; Biological Products; Humans; Immunosuppressive Agents; Melanoma; Methotrexate; Risk Factors; Skin Neoplasms | 2023 |
Leptomeningeal metastases from a primary central nervous system melanoma: a case report and literature review.
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Chemoradiotherapy; Female; Humans; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Tomography, X-Ray Computed | 2014 |
Intralesional agents in the management of cutaneous malignancy: a review.
Topics: Aminolevulinic Acid; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Injections, Intralesional; Interferon-alpha; Interleukin-2; Lymphoma, B-Cell; Melanoma; Methotrexate; Neoplasm Metastasis; Rituximab; Skin Neoplasms | 2011 |
Development of two primary malignant melanomas after treatment with adalimumab: a case report and review of the possible link between biological therapy with TNF-alpha antagonists and melanocytic proliferation.
Topics: Adalimumab; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Proliferation; Humans; Leg; Male; Melanocytes; Melanoma; Methotrexate; Scalp; Skin Neoplasms; Treatment Outcome; Tumor Necrosis Factor-alpha | 2010 |
Cutaneous melanoma in patients in treatment with biological therapy: review of the literature and case report.
Topics: Adalimumab; Aged; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Biological Therapy; Humans; Male; Melanoma; Methotrexate; Skin Neoplasms | 2011 |
Experience gained in immunotherapy from the immunopharmacology of BCG leading to a second generation of systemic immunity adjuvants.
Topics: Adjuvants, Immunologic; Animals; Aziridines; BCG Vaccine; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Immunologic; Humans; Immunotherapy; Leucine; Leukemia L1210; Leukemia, Lymphoid; Levamisole; Lymphoma, Non-Hodgkin; Melanoma; Methotrexate; Mice; Neoplasms; Propionibacterium acnes; T-Lymphocytes, Regulatory; Thymosin | 1980 |
Neurologic complications of systemic cancer.
Topics: Arachnoid; Bacterial Infections; Brain; Brain Neoplasms; Cerebrovascular Disorders; Cisplatin; Disseminated Intravascular Coagulation; Electroencephalography; Endocarditis; Fluorouracil; Humans; Lung Neoplasms; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Paraneoplastic Syndromes; Pia Mater; Prognosis; Spinal Cord Compression; Spinal Cord Neoplasms; Tomography, X-Ray Computed; Vinca Alkaloids | 1985 |
The use of cytotoxic drugs in the surgery of malignant disease.
Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Female; Fluorouracil; Head; Head and Neck Neoplasms; Hodgkin Disease; Humans; Injections, Intra-Arterial; Leg; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Vinblastine; Wilms Tumor | 1968 |
Cytokinetics in diseases of epidermal hyperplasia.
Topics: Cell Division; Female; Humans; Hyperplasia; Ichthyosis; Keratosis; Kinetics; Melanoma; Methotrexate; Psoriasis; Skin; Skin Diseases; Skin Neoplasms; Uterine Cervical Neoplasms | 1973 |
11 trial(s) available for methotrexate and Malignant Melanoma
| Article | Year |
|---|---|
Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Subcutaneous; Lomustine; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen; Time Factors; Treatment Outcome; Vinblastine | 2003 |
Newer techniques in cancer chemotherapy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bleomycin; Bone Marrow Transplantation; Carcinoma; Cells, Cultured; Child; Cisplatin; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hepatic Artery; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Mechlorethamine; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Osteosarcoma; Peritoneal Cavity; Pleura | 1984 |
Clinical trials of chemotherapy and chemoimmunotherapy in primary malignant melanoma.
Topics: Clinical Trials as Topic; Dacarbazine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunotherapy; Male; Melanoma; Methotrexate; Procarbazine; Streptonigrin; Vinblastine | 1982 |
Treatment of advanced malignant melanoma with high dose methotrexate and folinic acid rescue.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Infusions, Parenteral; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms | 1982 |
[Pathomorphosis of metastatic malignant melanoma of the skin as effected by preoperative endolymphatic polychemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Humans; Injections, Intralymphatic; Lymphatic Metastasis; Melanoma; Methotrexate; Middle Aged; Preoperative Care; Prospidium; Skin Neoplasms; Survival Rate; Time Factors; Treatment Outcome | 1993 |
[Prevention and treatment of regional lymphatic metastasis of cutaneous melanoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Humans; Injections, Intralymphatic; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Methotrexate; Neoplasm Staging; Preoperative Care; Prospidium; Skin Neoplasms; Survival Rate | 1993 |
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cytarabine; Delayed-Action Preparations; Disease Progression; Female; Humans; Injections, Spinal; Lung Neoplasms; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Survival Rate; Survivors | 1999 |
Phase II study of high-dose methotrexate in patients with advanced malignant melanoma.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Melanoma; Methotrexate; Middle Aged | 1979 |
Immunology and adjuvant chemoimmunotherapy of breast cancer.
Topics: Aged; Animals; Antibodies, Neoplasm; BCG Vaccine; Breast Neoplasms; Carcinoma; Chick Embryo; Cyclophosphamide; Female; Fluorouracil; Humans; Immunotherapy; Lymphatic Metastasis; Male; Melanoma; Methotrexate; Middle Aged; Prospective Studies; Sarcoma | 1976 |
Combination intraventricular chemotherapy for meningeal neoplasia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intraventricular; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Thiotepa; Urinary Bladder Neoplasms | 1986 |
Low dosage methotrexate (NSC-740) and cyclophosphamide (NSC 26271) for solid tumors.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Radiography; Rectal Neoplasms; Stomatitis; Wilms Tumor | 1970 |
183 other study(ies) available for methotrexate and Malignant Melanoma
| Article | Year |
|---|---|
Synthesis of methotrexate-antibody conjugates by regiospecific coupling and assessment of drug and antitumor activities.
Topics: Antibodies, Monoclonal; Chemical Phenomena; Chemistry; Humans; Immunoglobulin G; Immunotoxins; Kidney Neoplasms; Melanoma; Methotrexate; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Molecular characterization of human and rat organic anion transporter OATP-D.
Topics: Alprostadil; Amino Acid Sequence; Animals; Anions; Blotting, Northern; Brain Chemistry; Burkitt Lymphoma; Dinoprostone; DNA, Complementary; HeLa Cells; HL-60 Cells; Humans; K562 Cells; Leukemia, Lymphoid; Lung Neoplasms; Melanoma; Molecular Sequence Data; Oocytes; Organic Anion Transporters; Rats; RNA, Messenger; Xenopus laevis | 2003 |
Effect of methotrexate on melanoma risk in older adults: Secondary analysis of a randomised controlled trial.
Topics: Aged; Aged, 80 and over; Dermatologic Agents; Humans; Melanoma; Methotrexate; Randomized Controlled Trials as Topic; Risk Assessment; Skin Neoplasms | 2022 |
Risk of malignant melanoma and non-melanoma skin cancer in rheumatoid arthritis patients initiating methotrexate versus hydroxychloroquine: a cohort study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Humans; Hydroxychloroquine; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Skin Neoplasms | 2023 |
Identification of Active Compounds against Melanoma Growth by Virtual Screening for Non-Classical Human DHFR Inhibitors.
Topics: Antineoplastic Agents; Folic Acid Antagonists; Humans; Melanoma; Methotrexate; Tetrahydrofolate Dehydrogenase | 2022 |
Response to the feasibility of Kreher et al's "Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: methotrexate, alkylating agents, biologics, and small molecule inhibitors".
Topics: Alkylating Agents; Biological Products; Feasibility Studies; Humans; Immunosuppressive Agents; Melanoma; Methotrexate; Skin Neoplasms | 2023 |
Methotrexate treatment for patients with psoriasis and risk of cutaneous melanoma: a nested case-control study.
Topics: Australia; Case-Control Studies; Humans; Melanoma; Methotrexate; Psoriasis; Retrospective Studies; Skin Neoplasms; Sweden | 2020 |
Do we need to fear methotrexate?
Topics: Case-Control Studies; Fear; Humans; Melanoma; Methotrexate; Psoriasis; Skin Neoplasms | 2020 |
Resolution of pembrolizumab-associated lichenoid dermatitis with a single dose of methotrexate.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Female; Humans; Immunosuppressive Agents; Lichenoid Eruptions; Melanoma; Methotrexate; Middle Aged | 2020 |
This Month in JAAD: June 2021.
Topics: Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury; Dermoscopy; Humans; Melanoma; Methotrexate; Phototherapy; Psoriasis; Risk Assessment; Risk Factors; Skin; Skin Neoplasms; Skin Pigmentation; Vitiligo | 2021 |
Durable complete remission of leptomeningeal melanoma by intrathecal methotrexate maintained with systemic ipilimumab.
Topics: Adult; Dermatologic Agents; Humans; Immune Checkpoint Inhibitors; Injections, Spinal; Ipilimumab; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Treatment Outcome | 2021 |
Methotrexate increases the risk of melanoma: or does it?
Topics: Cell Survival; Humans; Melanoma; Methotrexate; Risk | 2017 |
Methotrexate treatment in patients with a history of cutaneous melanoma and the risk of a consecutive primary melanoma: A national retrospective registry-based cohort study.
Topics: Adult; Aged; Female; Humans; Immunosuppressive Agents; Incidence; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms, Second Primary; Registries; Retrospective Studies; Skin Neoplasms; Sweden | 2017 |
Pembrolizumab-associated inflammatory myopathy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Fatal Outcome; Female; Humans; Melanoma; Methotrexate; Myositis | 2018 |
Methotrexate Exposure and Risk of Cutaneous Malignant Melanoma: No Evidence of a Dose-response Relationship.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Incidence; Male; Melanoma; Methotrexate; Middle Aged; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Skin Neoplasms; Sweden; Time Factors | 2018 |
Methotrexate-Coated Complexes of Plasmid DNA and Polyethylenimine for Gene Delivery.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Cell Line, Tumor; DNA; Endocytosis; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Liver; Melanoma; Methotrexate; Mice; Nanoparticles; Plasmids; Polyethyleneimine; Spleen; Transfection; Transgenes | 2018 |
Methotrexate and melanoma-specific mortality.
Topics: Aged; Aged, 80 and over; Dermatology; Female; Humans; Kaplan-Meier Estimate; Male; Melanoma; Methotrexate; Middle Aged; Rheumatology; Skin Neoplasms; Sweden | 2019 |
Immune checkpoint inhibitor-induced lymphocytic fasciitis.
Topics: Antineoplastic Agents, Immunological; Biopsy; Fasciitis; Forearm; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Staging; Nivolumab; Prednisolone; Programmed Cell Death 1 Receptor; Treatment Outcome | 2018 |
Primary malignant melanoma of the urethra in a patient with rheumatoid arthritis treated with methotrexate.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Melanoma; Methotrexate; Urethra; Urethral Neoplasms | 2019 |
Efficacy and Toxicity of Pembrolizumab in Pediatric Metastatic Recurrent Melanoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Melanoma; Methotrexate; Neoplasm Recurrence, Local; Soft Tissue Neoplasms; Steroids; Treatment Outcome; Uveitis | 2019 |
Directed phenotype switching as an effective antimelanoma strategy.
Topics: Apoptosis; Catechin; Cell Differentiation; Cell Line, Tumor; DNA Damage; E2F1 Transcription Factor; Humans; Melanoma; Methotrexate; Microphthalmia-Associated Transcription Factor; Phenotype; Thymine Nucleotides | 2013 |
Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Female; Gene Silencing; Humans; Melanoma; Methotrexate; Methylation; Mice; Myosin Heavy Chains; Myosin Type V; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays | 2013 |
Identification of novel small compounds that restore E-cadherin expression and inhibit tumor cell motility and invasiveness.
Topics: Adenocarcinoma; Antineoplastic Agents; Cadherins; Cell Line; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, Antitumor; High-Throughput Screening Assays; Humans; Melanoma; Methotrexate; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Small Molecule Libraries | 2013 |
Flipping the phenotypic switch on a novel antimelanoma differentiation strategy.
Topics: Animals; Catechin; Cell Differentiation; Cell Line, Tumor; Humans; Melanocytes; Melanoma; Methotrexate; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Phenotype | 2013 |
Intralesional Methotrexate for Treatment of Invasive Squamous Cell Carcinomas in a Patient Taking Vemurafenib for Treatment of Metastatic Melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Humans; Indoles; Melanoma; Methotrexate; Middle Aged; Sulfonamides; Treatment Outcome; Vemurafenib | 2016 |
Methotrexate inhibits the viability of human melanoma cell lines and enhances Fas/Fas-ligand expression, apoptosis and response to interferon-alpha: rationale for its use in combination therapy.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cellular Senescence; DNA Methylation; Drug Synergism; Drug Therapy, Combination; Fas Ligand Protein; fas Receptor; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; Methotrexate; Promoter Regions, Genetic; Recombinant Proteins | 2014 |
Enhanced antimelanoma activity of methotrexate and zoledronic acid within polymeric sandwiches.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Diphosphonates; Drug Screening Assays, Antitumor; Endocytosis; Humans; Imidazoles; Melanoma; Methotrexate; Polymers; Spectroscopy, Fourier Transform Infrared; Zoledronic Acid | 2014 |
Oxidative stress inhibits distant metastasis by human melanoma cells.
Topics: Animals; Antioxidants; Female; Folic Acid; Gene Knockdown Techniques; Humans; Male; Melanoma; Methotrexate; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred NOD; Mice, SCID; Minor Histocompatibility Antigens; NADP; Neoplasm Metastasis; Neoplasm Transplantation; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors | 2015 |
In vitro and in vivo evaluation of sandwich-like mesoporous silica nanoflakes as promising anticancer drug delivery system.
Topics: Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Delivery Systems; Female; Fibroblasts; Humans; Injections, Intravenous; Male; Melanoma; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Polyethylene Glycols; Porosity; Silicon Dioxide; Tissue Distribution | 2016 |
Superficial spreading melanoma in a psoriatic plaque of a patient with psoriatic arthritis.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Psoriatic; Back Pain; Biopsy; Cholecalciferol; Dendritic Cells; Female; Humans; Immunohistochemistry; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Middle Aged; Ointments; PUVA Therapy; Retinoids; Severity of Illness Index; Skin Neoplasms | 2016 |
Methotrexate treatment and risk for cutaneous malignant melanoma: a retrospective comparative registry-based cohort study.
Topics: Adult; Age Distribution; Aged; Female; Humans; Immunosuppressive Agents; Incidence; Kaplan-Meier Estimate; Male; Melanoma; Melanoma, Cutaneous Malignant; Methotrexate; Middle Aged; Registries; Retrospective Studies; Risk Factors; Sex Distribution; Skin Neoplasms; Sweden | 2017 |
Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with methotrexate.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms | 2008 |
[Adjuvant chemotherapy as a component of complex treatment for skin melanoma].
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Dacarbazine; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Male; Melanoma; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Radiotherapy, Adjuvant; Skin Neoplasms; Survival Analysis; Treatment Outcome; Vincristine | 2008 |
The critical role of alpha-folate receptor in the resistance of melanoma to methotrexate.
Topics: Aged; Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Male; Melanocytes; Melanoma; Melanosomes; Methotrexate; Mice; Protein Isoforms; Receptors, Cell Surface | 2009 |
Metastatic malignant melanoma and dermatomyositis: A paraneoplastic phenomenon.
Topics: Adult; Alendronate; Antibodies, Antinuclear; Calcium; Dermatologic Agents; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Melanoma; Methotrexate; Paraneoplastic Syndromes; Positron-Emission Tomography; Prednisolone; Skin Neoplasms; Treatment Outcome; Vitamin D | 2011 |
Adrenergic urticaria and rheumatoid arthritis in a patient with melanoma: an intricate medical management.
Topics: Adrenergic beta-Antagonists; Arthritis, Rheumatoid; Female; Glucocorticoids; Histamine Antagonists; Humans; Immunosuppressive Agents; Melanoma; Methotrexate; Middle Aged; Propranolol; Stress, Psychological; Urticaria | 2012 |
New insight into rheumatoid arthritis management. The disease and the drugs used to treat it have been linked to cardiovascular disease, melanoma, and fracture.
Topics: Adult; Age Factors; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Female; Fractures, Bone; Humans; Male; Melanoma; Methotrexate; Middle Aged; Risk Factors; Skin Neoplasms | 2012 |
Nodular melanoma arising in a patient treated with anti-tumor necrosis factor alpha antagonists.
Topics: Acitretin; Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cyclosporine; Dermatologic Agents; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Male; Melanoma; Methotrexate; Psoriasis; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Skin Neoplasms; Treatment Outcome; Tumor Necrosis Factor-alpha | 2012 |
Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance.
Topics: Amino Acid Sequence; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Folic Acid; Humans; Melanoma; Methotrexate; Mice; Molecular Sequence Data; Protein Kinases; Protein Processing, Post-Translational; S Phase Cell Cycle Checkpoints; Skin Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Thymine Nucleotides; Transcription, Genetic | 2012 |
Treatment of malignant melanoma of the orbit with intra-arterial methotrexate.
Topics: Choroid Neoplasms; Humans; Melanoma; Methotrexate; Orbit | 1962 |
Advances in the treatment of skin diseases.
Topics: Adrenal Cortex Hormones; Aminopterin; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Chelating Agents; Dermabrasion; Dermatologic Agents; Dermatology; Griseofulvin; Histamine H1 Antagonists; Humans; Melanoma; Methotrexate; Methoxsalen; Ointments; Perfusion; Phenols; Skin Diseases; Vitamin A | 1962 |
A METHOD OF CONTINUOUS INTRAVASCULAR INFUSION OF METHOTREXATE IN THE PALLIATIVE TREATMENT OF MALIGNANT DISEASE IN PATIENTS.
Topics: Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Palliative Care; Pelvic Neoplasms | 1963 |
THE TREATMENT OF MALIGNANT DISEASE BY REGIONAL CHEMOTHERAPY.
Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Neoplasms; Neoplasms, Muscle Tissue; Nitrogen Mustard Compounds; Sarcoma; Toxicology; Triethylenemelamine | 1963 |
REGIONAL CHEMOTHERAPY IN MALIGNANT DISEASE: A REVIEW OF FIFTEEN CASES.
Topics: Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Female; Hormones; Humans; Injections, Intra-Arterial; Melanoma; Methotrexate; Neoplasms; Ovarian Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms | 1963 |
THE INTRALYMPHATIC ADMINISTRATION OF RADIOACTIVE ISOTOPES AND CANCER CHEMOTHERAPEUTIC DRUGS.
Topics: Abdominal Neoplasms; Angiography; Breast Neoplasms; Geriatrics; Gold; Humans; Injections; Iodine Isotopes; Leukemia; Lymphatic Metastasis; Lymphatic System; Lymphography; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Melphalan; Methotrexate; Neoplasms; Radioisotopes; Radionuclide Imaging; Retroperitoneal Neoplasms; Scandium; Thiotepa; Yttrium | 1964 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; Chromosomes, Human; Endometriosis; Female; Fluorouracil; Geriatrics; Humans; Leukocytes; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Ovarian Neoplasms; Sarcoma; Thiotepa; Uterine Cervical Neoplasms; Uterine Neoplasms; Vinblastine | 1964 |
STUDIES ON HUMAN MELANOMA CELLS IN TISSUE CULTURE. II. EFFECTS OF SEVERAL CANCER CHEMOTHERAPEUTIC AGENTS ON CYTOLOGY AND GROWTH.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Chlorambucil; Dactinomycin; Fluorouracil; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Thiotepa; Tissue Culture Techniques | 1964 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Humans; In Vitro Techniques; Intestinal Neoplasms; Leukemia; Mechlorethamine; Melanoma; Mercaptopurine; Methotrexate; Neoplasms; Pharyngeal Neoplasms; Respiratory Tract Neoplasms; Stomach Neoplasms; Thiotepa | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exfoliative; Equipment and Supplies; Floxuridine; Fluorouracil; Humans; Infusion Pumps; Infusions, Parenteral; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycin; Mitomycins; Pancreatic Neoplasms; Stomach Neoplasms; Testicular Neoplasms; Thyroid Neoplasms; Tongue Neoplasms; Toxicology | 1964 |
JET INJECTION OF DRUGS INTO MALIGNANT NEOPLASMS.
Topics: Breast Neoplasms; Drug Therapy; Equipment and Supplies; Humans; Injections; Injections, Jet; Melanoma; Methotrexate; Mouth Neoplasms; Neoplasms; Thiotepa | 1964 |
EFFECT OF HYPERBARIC OXYGEN AND CANCER CHEMOTHERAPY ON GROWTH OF ANIMAL TUMORS.
Topics: Animals; Cricetinae; Humans; Hyperbaric Oxygenation; Injections, Intraperitoneal; Lung Neoplasms; Mechlorethamine; Melanoma; Methotrexate; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pathology; Peritoneal Cavity; Research | 1964 |
Cure of metastatic melanoma with surgery, low-dose methotrexate and heparin: a case report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Heparin; Humans; Melanoma; Methotrexate; Recurrence; Skin Neoplasms; Time Factors; Treatment Outcome | 2004 |
Primary malignant melanoma of the urethra.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cystectomy; Diagnostic Errors; Doxorubicin; Humans; Lymph Node Excision; Male; Melanoma; Methotrexate; Neoplasm Invasiveness; Neoplasm Seeding; Penis; Prostatectomy; Urethral Neoplasms; Urinary Bladder Neoplasms; Urinary Diversion; Vinblastine | 2005 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazines; Hydroxyurea; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Melphalan; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Perfusion; Vincristine | 1967 |
In vivo studies of radioactive phosphorus in malignant tumours.
Topics: Adult; Aged; Animals; Autoradiography; Breast Neoplasms; Bronchial Neoplasms; Densitometry; Female; Humans; Mammary Neoplasms, Experimental; Melanoma; Methotrexate; Methylcholanthrene; Middle Aged; Phosphorus; Phosphorus Isotopes; Rats | 1967 |
Re-evaluation of methotrexate as an anticancer drug.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma; Female; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nose Neoplasms; Ovarian Neoplasms; Sarcoma | 1967 |
Brain tumor chemotherapy with methotrexate given intrathecally. A new technique.
Topics: Adrenal Cortex Hormones; Adult; Aged; Brain Neoplasms; Child; Ependymoma; Glioma; Humans; Injections, Spinal; Lymphoma; Medulloblastoma; Melanoma; Methotrexate | 1967 |
[Dye concentration measurements for the determination of leakage during and following normothermic cytostatic perfusion in the treatment of tumors of the extremities].
Topics: Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Histiocytoma, Benign Fibrous; Humans; Indigo Carmine; Indoles; Male; Melanoma; Methotrexate; Osteosarcoma; Soft Tissue Neoplasms; Spectrophotometry; Vincristine | 1984 |
Fluctuations in phosphoribosyl pyrophosphate levels in monolayer tumor cell lines. Effects of drugs.
Topics: Animals; Aspartic Acid; Buffers; Cell Line; Cytological Techniques; Fibroblasts; Humans; Melanoma; Methotrexate; Mice; Pentosephosphates; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate; Purine Nucleosides; Trypsin | 1984 |
Intra-arterial infusion in tumors of the pelvis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Floxuridine; Fluorouracil; Humans; Iliac Artery; Infusions, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Ovarian Neoplasms; Pelvic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1983 |
Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.
Topics: Animals; Cell Line; Chromosome Aberrations; DNA; DNA Restriction Enzymes; Drug Resistance; Gene Amplification; Karyotyping; Lymphoma; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; T-Lymphocytes | 1981 |
Single agent chemotherapy for head and neck cancers. The murine subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Resistance; Female; Head and Neck Neoplasms; Humans; Kidney; Melanoma; Methotrexate; Mice; Neoplasm Transplantation | 1983 |
Mitomycin C combination therapy against murine tumor systems. Effectiveness with cyclophosphamide and methotrexate.
Topics: Animals; Antibiotics, Antineoplastic; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Leukemia P388; Melanoma; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitomycin; Mitomycins; Neoplasms, Experimental | 1983 |
[Multiple primary malignant melanomas in psoriasis vulgaris under long-term methotrexate therapy].
Topics: Dose-Response Relationship, Drug; Humans; Long-Term Care; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Psoriasis; Skin Neoplasms | 1984 |
In vitro sensitivity and resistance of cultured human squamous carcinoma cells to cis-platinum and methotrexate.
Topics: Carcinoma, Squamous Cell; Cell Count; Cell Line; Cell Survival; Cisplatin; Colony-Forming Units Assay; Fibrosarcoma; Head and Neck Neoplasms; Humans; Melanoma; Methotrexate; Tumor Stem Cell Assay | 1984 |
[Xenogeneic transplantation of human malignant melanoma under high-dose immunosuppression].
Topics: Animals; Azathioprine; Humans; Immunosuppression Therapy; Male; Melanoma; Methotrexate; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Transplantation, Heterologous | 1984 |
Protection of cells from methotrexate toxicity by 7-hydroxymethotrexate.
Topics: Acute Disease; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Humans; Leukemia, Lymphoid; Melanoma; Methotrexate; Time Factors | 1984 |
Paradoxical response of malignant melanoma to methotrexate in vivo and in vitro.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Choriocarcinoma; Humans; Leucovorin; Leukemia, Lymphoid; Male; Melanoma; Methotrexate; Mice | 1983 |
Assessment of antimetabolite cytotoxicity: a comparison of clonogenic assays and tritiated deoxyuridine incorporation.
Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leukemia L1210; Melanoma; Methotrexate; Mice; Tritium | 1983 |
Experimental and clinical observations of the effects of cytotoxic chemotherapeutic drugs on wound healing.
Topics: Adult; Aged; Animals; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Humans; Male; Melanoma; Methotrexate; Middle Aged; Rats; Rats, Inbred BUF; Retrospective Studies; Skin Neoplasms; Tensile Strength; Wound Healing | 1984 |
Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme.
Topics: Adenosine; Azaserine; Breast Neoplasms; Cell Line; Cell Survival; Humans; Leukemia; Melanoma; Methotrexate; Neoplasms; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Thionucleosides | 1981 |
Purine modulation of methotrexate cytotoxicity in mammalian cell lines.
Topics: Animals; Cell Line; Cell Survival; Deoxyribonucleotides; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Melanoma; Methotrexate; Mice; Purines | 1982 |
Chemotherapy of malignant melanoma.
Topics: Daunorubicin; Dicarboxylic Acids; Drug Combinations; Drug Resistance; Humans; Levodopa; Melanocyte-Stimulating Hormones; Melanoma; Methotrexate; Nitrosourea Compounds; Receptors, Estrogen; Tretinoin | 1982 |
Satellite DNA in large marker chromosomes of methotrexate-resistant mouse cells.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Chromosome Banding; Chromosomes; DNA, Satellite; Drug Resistance; Heterochromatin; Melanoma; Methotrexate; Mice; Nucleic Acid Hybridization; Sister Chromatid Exchange | 1980 |
Rapid plasma clearance and reduced rate and extent of urinary elimination of parenterally administered methotrexate as a result of severe vomiting and diarrhoea.
Topics: Diarrhea; Female; Humans; Injections, Intramuscular; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms; Vomiting | 1980 |
Natural resistance to methotrexate in human melanomas.
Topics: Drug Resistance; Humans; Melanoma; Methotrexate; Skin Neoplasms; Tetrahydrofolate Dehydrogenase | 1980 |
[Malignant melanoma of the vagina].
Topics: Adult; BCG Vaccine; Cyclophosphamide; Drug Therapy, Combination; Eyelid Neoplasms; Female; Fluorouracil; Humans; Lymph Node Excision; Melanoma; Methotrexate; Pelvic Exenteration; Vaginal Neoplasms; Vincristine | 1980 |
High-volume intraperitoneal chemotherapy with methotrexate in patients with cancer.
Topics: Adenocarcinoma; Dialysis; Female; Humans; Injections, Intraperitoneal; Melanoma; Methotrexate; Ovarian Neoplasms | 1981 |
Chemotherapy against human melanoma in the hamster cheek pouch.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carmustine; Cheek; Cricetinae; Cyclophosphamide; Dacarbazine; Doxorubicin; Fluorouracil; Humans; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Transplantation; Neoplasms, Experimental; Vincristine | 1980 |
Chemosensitivity testing of human malignant melanoma. A retrospective analysis of clinical response and in vitro drug sensitivity.
Topics: Antineoplastic Agents; Bleomycin; Carboplatin; Carmustine; Cisplatin; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Forecasting; Humans; In Vitro Techniques; Lymphatic Metastasis; Melanoma; Methotrexate; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction; Retrospective Studies; Skin Neoplasms; Tumor Cells, Cultured; Vindesine | 1994 |
[Regional cytostatic perfusion of the extremities in patients with malignant melanoma and soft tissue sarcoma--therapeutic applications and results].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Extremities; Follow-Up Studies; Humans; Hyperthermia, Induced; Melanoma; Melphalan; Methotrexate; Palliative Care; Sarcoma; Sarcoma, Ewing; Skin Neoplasms; Soft Tissue Neoplasms; Survival Rate; Vincristine | 1993 |
Synchronization of cells in the S phase of the cell cycle by 3'-azido-3'-deoxythymidine: implications for cell cytotoxicity.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Leukemia; Melanoma; Methotrexate; Pancreatic Neoplasms; S Phase; Tumor Cells, Cultured; Zidovudine | 1995 |
Teaching cancer chemotherapy by means of a computer simulation.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cause of Death; Computer Simulation; Computer-Assisted Instruction; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Leukemia, Experimental; Melanoma; Methotrexate; Mice; Models, Biological; Models, Educational; Neoplasms, Experimental; Sarcoma, Experimental; Software; Survival Rate; Teaching | 1994 |
Hypoxia-induced resistance to doxorubicin and methotrexate in human melanoma cell lines in vitro.
Topics: Cell Hypoxia; Cell Survival; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Melanoma; Methotrexate; Oxygen; Tumor Cells, Cultured | 1994 |
Intralesional implant for treatment of primary oral malignant melanoma in dogs.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cisplatin; Delayed-Action Preparations; Dog Diseases; Dogs; Drug Implants; Female; Gels; Injections, Intralesional; Linear Models; Male; Melanoma; Methotrexate; Mouth Neoplasms; Neoplasm Recurrence, Local; Oropharyngeal Neoplasms; Survival Rate; Treatment Outcome | 1994 |
Association of methotrexate, rheumatoid arthritis, and melanoma in 2 patients.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Melanoma; Methotrexate | 1997 |
[Use of adjuvant therapy in patients with metastasis of melanoma to regional lymph nodes].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Injections, Intralymphatic; Interferon Type I; Lymph Node Excision; Lymphatic Metastasis; Male; Melanoma; Methotrexate; Middle Aged; Preoperative Care; Prospidium; Recombinant Proteins; Skin Neoplasms; Time Factors | 1998 |
Multiple malignant melanomas in a patient with RA treated with methotrexate.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Male; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms | 1998 |
Adaptive response towards adriamycin in vitro: circumvention with verapamil.
Topics: Animals; Antineoplastic Agents; Calcium Channel Blockers; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Doxorubicin; Drug Combinations; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Melanoma; Methotrexate; Tumor Cells, Cultured; Verapamil; Vinblastine | 1999 |
Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloroplatinum(II): therapeutic implications.
Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Cisplatin; Humans; Intramolecular Oxidoreductases; Melanoma; Methotrexate; Paclitaxel; Tumor Cells, Cultured | 2000 |
The use of millimeter band electromagnetic waves in clinical oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Cyclophosphamide; Electromagnetic Fields; Female; Fluorouracil; Humans; Medical Oncology; Melanoma; Methotrexate; Radiotherapy, Adjuvant; Skin Neoplasms; Wound Healing | 2000 |
[Treatment of advanced neoplasms in the jaw].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Carotid Artery, External; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Edema; Facial Neoplasms; Fibrosarcoma; Humans; Injections, Intra-Arterial; Jaw Neoplasms; Melanoma; Methotrexate; Middle Aged; Papilloma; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage | 1975 |
Effects of antineoplastic agents on wound healing in mice.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Dactinomycin; Doxorubicin; Fluorouracil; Injections, Intraperitoneal; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Vincristine; Wound Healing | 1975 |
Flow microfluorometric patterns of human bone marrow and tumor cells in response to cancer chemotherapy.
Topics: Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Ethidium; Fluorometry; Humans; Leucovorin; Leukemia, Lymphoid; Melanoma; Methotrexate; Neoplasms; Staining and Labeling | 1976 |
[Adverse effects of drugs on the skin--significance, survey and prospects].
Topics: Adrenergic beta-Antagonists; Allergens; Alopecia; Bleomycin; Drug Eruptions; Humans; Melanoma; Methotrexate; Penicillamine; Penicillins; Psoriasis; Skin Diseases, Vesiculobullous | 1978 |
[Extensive disseminated cutaneous neoplasms; role of cytophotometry in determining the correct chemotherapy].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Evaluation; Facial Neoplasms; Histological Techniques; Humans; Melanoma; Methotrexate; Photometry; Skin Neoplasms; Time Factors; Vinblastine | 1978 |
Combination chemotherapy with vinblastine, bleomycin and methotrexate in DTIC-resistant metastatic melanoma.
Topics: Adult; Antineoplastic Agents; Bleomycin; Dacarbazine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Vinblastine | 1979 |
Cytostatic treatment of meningeal blastoses.
Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Humans; Injections, Spinal; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis | 1979 |
Intraperitoneal contrast infusion for assessment of intraperitoneal fluid dynamics.
Topics: Adult; Antineoplastic Agents; Ascitic Fluid; Contrast Media; Female; Fluorouracil; Humans; Injections, Intraperitoneal; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Peritoneal Neoplasms; Peritoneum; Tomography, X-Ray Computed | 1979 |
Adjuvant chemotherapy or chemoimmunotherapy in the management of primary malignant melanoma of level III, IV, or V.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bacterial Vaccines; BCG Vaccine; Dacarbazine; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Procarbazine; Propionibacterium acnes; Streptonigrin; Thiotepa; Vinblastine | 1978 |
Recent trends in chemotherapy of solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms | 1975 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Liver Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Temporal Arteries; Time Factors | 1975 |
Future prospects for immunotherapy.
Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Dacarbazine; Guinea Pigs; Humans; Immunotherapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver Neoplasms; Melanoma; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Sarcoma | 1975 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukemia; Lung Neoplasms; Lymphoma; Melanoma; Methotrexate; Neoplasms; Osteosarcoma; Tetrahydrofolates; Thymidine | 1977 |
High-dose methotrexate in malignant melanoma.
Topics: Adult; Aged; Female; Humans; Intestinal Neoplasms; Leucovorin; Leukopenia; Male; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms | 1979 |
Chemotherapy of common solid tumours in a general surgical unit.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Quality of Life; Vincristine; Vomiting | 1979 |
The development of resistance to methotrexate in a mouse melanoma cell line. I. Characterisation of the dihydrofolate reductases and chromosomes in sensitive and resistant cells.
Topics: Animals; Cell Line; Chromosome Aberrations; DNA, Neoplasm; Drug Resistance; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Tetrahydrofolate Dehydrogenase | 1979 |
[Histochemical demonstration of tetrahydrofolate dehydrogenase in human bone marrow: apparent enzymatic induction after administration of folic acid antagonists].
Topics: Bone Marrow; Enzyme Induction; Female; Folic Acid Antagonists; Humans; Melanoma; Methotrexate; Tetrahydrofolate Dehydrogenase | 1979 |
Effect of adriamycin and high-dose methotrexate chemotherapy on in vivo and in vitro cell-mediated immunity in cancer patients.
Topics: Adult; Aged; Doxorubicin; Drug Therapy, Combination; Female; Humans; Immunity, Cellular; In Vitro Techniques; Lymphocytes; Male; Melanoma; Methotrexate; Middle Aged; Sarcoma; Skin Tests; Soft Tissue Neoplasms | 1978 |
Chemotherapy of unresectable or recurrent metastatic malignant melanomas: an update.
Topics: Amphotericin B; BCG Vaccine; Dacarbazine; Drug Combinations; Estradiol Congeners; Female; Hot Temperature; Humans; Melanoma; Methotrexate; Neoplasm Metastasis; Nitrosourea Compounds; Skin Neoplasms | 1979 |
Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
Topics: Animals; Carcinoma; Cell Line; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Tegafur | 1976 |
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Kidney Neoplasms; Melanoma; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Ovarian Neoplasms; Thiotepa; Vincristine | 1975 |
[Immunological reactions of skin melanoma patients to nonspecific and adaptive immunotherapy].
Topics: Antigen-Antibody Reactions; BCG Vaccine; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunotherapy; Lectins; Lymphatic Metastasis; Lymphocyte Activation; Lymphocytes; Melanoma; Methotrexate; Recurrence; Remission, Spontaneous; Rosette Formation; Skin Neoplasms; Skin Tests; Tuberculin Test | 1977 |
Perfusion therapy for extremity melanoma.
Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Male; Melanoma; Melphalan; Methotrexate; Middle Aged | 1976 |
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo.
Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule; Fluorouracil; Granulocytes; Intestinal Mucosa; Kinetics; Lomustine; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Pyrimidine Nucleosides; Thymidine; Uridine | 1976 |
Perfusion therapy for skin cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Drug Therapy, Combination; Extremities; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Sarcoma; Sarcoma, Kaposi; Skin Neoplasms | 1975 |
High dose methotrexate therapy of solid tumors: observations relating to clinical toxicity.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Drug Therapy, Combination; Humans; Leucovorin; Melanoma; Methotrexate; Middle Aged; Neoplasms; Sarcoma; Soft Tissue Neoplasms | 1976 |
Systemic chemotherapy of advanced head and neck malignancies.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Imidazoles; Melanoma; Methotrexate; Neoplasms; Nitrosourea Compounds; Retrospective Studies; Sarcoma; Triazenes; Vincristine | 1975 |
[Evaluation of the immunological reactivity of melanoma patients using the rosette formation test].
Topics: Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Immune Adherence Reaction; Immunosuppressive Agents; Melanoma; Menstruation; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisolone; Vincristine | 1975 |
Endogenous gene and amplifiable cDNA construct both produce unstable t-PA mRNA in Bowes melanoma cells.
Topics: Cloning, Molecular; Drug Resistance; Gene Amplification; Half-Life; Humans; Melanoma; Methotrexate; Plasmids; Protein Biosynthesis; RNA, Messenger; Tissue Plasminogen Activator; Transfection; Tumor Cells, Cultured | 1992 |
Diagnosis and treatment of patients with meningeal carcinomatosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma; Cytarabine; Female; Humans; Injections, Spinal; Male; Melanoma; Meningeal Neoplasms; Methotrexate; Middle Aged; Retrospective Studies | 1992 |
High level expression of human proteins in murine hybridoma cells: induction by methotrexate in the absence of gene amplification.
Topics: Animals; Cell Line; Cloning, Molecular; Gene Expression; Genetic Vectors; Humans; Hybridomas; Melanoma; Membrane Fusion; Methotrexate; Mice; Plasminogen Activators; Poly A; Restriction Mapping; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Tissue Plasminogen Activator; Transfection; Urokinase-Type Plasminogen Activator | 1991 |
Effects of antimetabolites on adenovirus replication in sensitive and resistant human melanoma cell lines.
Topics: Adenoviridae; Cell Survival; Cytarabine; DNA; Drug Resistance; Humans; Kinetics; Melanoma; Methotrexate; RNA; Tetrahydrofolate Dehydrogenase; Thioguanine; Tumor Cells, Cultured; Virus Replication | 1990 |
Keratin and carcinoembryonic antigen (CEA) in human melanoma cells.
Topics: Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Extracts; Doxorubicin; Fluorescent Antibody Technique; HeLa Cells; Humans; Immunodiffusion; Immunohistochemistry; Keratins; Melanoma; Methotrexate; Microscopy, Electron; Transplantation, Heterologous; Tumor Cells, Cultured | 1991 |
Intracellular delivery of drugs by liposomes containing P0 glycoprotein from peripheral nerve myelin into human M21 melanoma cells.
Topics: Cell Adhesion Molecules, Neuronal; Dextrans; Drug Carriers; Fluorescent Antibody Technique; Folic Acid; Humans; Inulin; Lipid Metabolism; Liposomes; Melanoma; Methotrexate; Microscopy, Fluorescence; Myelin P0 Protein; Myelin Proteins; Myelin Sheath; Peripheral Nerves; Tumor Cells, Cultured | 1991 |
Regression of human melanoma xenografts in nude mice injected with methotrexate linked to monoclonal antibody 225.28 to human high molecular weight-melanoma associated antigen.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Humans; Immunotoxins; Melanoma; Melanoma-Specific Antigens; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Weight; Neoplasm Proteins; Neoplasm Transplantation; Transplantation, Heterologous | 1991 |
High frequency of double drug resistance in the B16 melanoma cell line.
Topics: Amides; Animals; Antineoplastic Agents; Aspartic Acid; Cell Line; Colony-Forming Units Assay; Drug Resistance; Drug Synergism; Gene Amplification; Melanoma; Methotrexate; Mice; Ouabain; Phosphonoacetic Acid; Pyrazoles; Ribonucleosides; Ribose | 1990 |
Toxicities of trichosanthin and alpha-momorcharin, abortifacient proteins from Chinese medicinal plants, on cultured tumor cell lines.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Division; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Drugs, Chinese Herbal; Fluorouracil; Humans; Liver Neoplasms; Melanoma; Methotrexate; Plant Proteins; Progesterone; Ribosomal Proteins; Ribosome Inactivating Proteins; Trichosanthin; Tumor Cells, Cultured | 1990 |
Rapid chemosensitivity assay with human normal and tumor cells in vitro.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Fibroblasts; Fluorouracil; Humans; Keratinocytes; Liver Neoplasms; Melanocytes; Melanoma; Methotrexate; Neutral Red; Time Factors; Tumor Cells, Cultured | 1990 |
[The prevention of skin melanoma metastases to the regional lymph nodes].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Humans; Injections, Intralymphatic; Lymphatic Metastasis; Melanoma; Methotrexate; Postoperative Care; Prospidium; Remission Induction; Skin Neoplasms | 1990 |
[Study of procreation capacity of men after treatment of their malignant tumors (melanoblastoma, thyroid carcinoma) with ionizing radiation and cytostatic agents].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cobalt Radioisotopes; Cyclophosphamide; Dacarbazine; Fertility; Fluorouracil; Humans; Male; Melanoma; Methotrexate; Radiotherapy Dosage; Sperm Count; Sperm Motility; Spermatozoa; Thyroid Neoplasms | 1990 |
Malignant melanoma associated with multiple therapies for psoriasis.
Topics: Adrenal Cortex Hormones; Adult; Coal Tar; Humans; Hydroxyurea; Male; Melanoma; Methotrexate; Photochemotherapy; Phototherapy; Psoriasis; Skin Neoplasms | 1989 |
Significance of antigen, drug, and tumor cell targets in the preclinical evaluation of doxorubicin, daunorubicin, methotrexate, and mitomycin-C monoclonal antibody immunoconjugates.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line; Cytotoxicity, Immunologic; Daunorubicin; Doxorubicin; Drug Combinations; Drug Evaluation; Lymphoma; Melanoma; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Mitomycins; Tumor Cells, Cultured | 1989 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Female; Fluorouracil; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Melphalan; Methotrexate; Middle Aged; Neoplasms; Procarbazine; Testicular Neoplasms; Vincristine | 1989 |
[Leakage measurements with the dye extraction method and direct methotrexate level determination (enzyme immunoassay) during and after regional cytostatic limb perfusion].
Topics: Chemotherapy, Cancer, Regional Perfusion; Dye Dilution Technique; Extremities; Humans; Immunoenzyme Techniques; Melanoma; Methotrexate; Skin Neoplasms | 1989 |
[Renal dipeptidylpeptidase IV excretion in drug-induced kidney changes].
Topics: Acute Kidney Injury; Adolescent; Adult; Aminopeptidases; CD13 Antigens; Cephalothin; Chemotherapy, Cancer, Regional Perfusion; Diatrizoate; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Female; Gentamicins; Glucuronidase; Humans; Hypertension, Renal; Kidney; Male; Melanoma; Methotrexate; Middle Aged; Pyelonephritis; Skin Neoplasms; Urography | 1986 |
[Excretion of the urinary enzymes alanine aminopeptidase and beta-glucuronidase in cystostatic perfusion therapy].
Topics: Adolescent; Adult; Aged; Aminopeptidases; Antineoplastic Combined Chemotherapy Protocols; CD13 Antigens; Chemotherapy, Cancer, Regional Perfusion; Female; Glucuronidase; Humans; Kidney Tubules, Proximal; Leg; Male; Melanoma; Methotrexate; Middle Aged; Pilot Projects; Skin Neoplasms; Vincristine | 1988 |
Drug/antibody conjugates. In vitro cytotoxicity of a human serum albumin-mediated conjugate of methotrexate with anti-MM46 monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Cytotoxicity, Immunologic; Humans; Mammary Neoplasms, Experimental; Melanoma; Methotrexate; Mice; Serum Albumin; Tumor Cells, Cultured | 1987 |
[Meningiosis neoplastica--clinical aspects and therapy. Experiences in 78 cases].
Topics: Breast Neoplasms; Combined Modality Therapy; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Melanoma; Meningeal Neoplasms; Meninges; Methotrexate; Skin Neoplasms | 1988 |
Antibody directed targeting of methotrexate-containing small unilamellar vesicles.
Topics: Antibodies, Neoplasm; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Cell Line; Chromatography, Gel; Cross-Linking Reagents; Fluorescent Antibody Technique; Growth Inhibitors; Humans; Immunoglobulin G; Immunohistochemistry; Kidney Neoplasms; Liposomes; Melanoma; Methotrexate | 1988 |
The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. IV. Therapy of murine melanoma B16 by human serum albumin-methotrexate derivative.
Topics: Animals; Drug Carriers; Female; Lung Neoplasms; Melanoma; Methotrexate; Mice; Mice, Inbred C57BL; Serum Albumin | 1988 |
Similarity in dynamics of single or double minute chromosomes incidence and number of chromosomal aberrations during long-term treatment of a human cell line with methotrexate.
Topics: Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes; Drug Resistance; Gene Amplification; Humans; Melanoma; Methotrexate | 1987 |
Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines.
Topics: Animals; Aspartic Acid; Cell Line; Drug Resistance; Gene Amplification; Mathematics; Melanoma; Methotrexate; Mice; Neoplasm Metastasis; Organophosphorus Compounds; Phenotype; Phosphonoacetic Acid | 1987 |
A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity.
Topics: Amines; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Binding Sites, Antibody; Chemical Phenomena; Chemistry; Maleic Anhydrides; Melanoma; Melanoma-Specific Antigens; Methotrexate; Mice; Neoplasm Proteins | 1987 |
Nonmelanoma skin tumors in long-term photochemotherapy treatment of psoriasis. An 8-year follow-up study.
Topics: Adult; Aged; Aging; Arsenic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Combined Modality Therapy; Dose-Response Relationship, Radiation; Etretinate; Follow-Up Studies; Humans; Melanoma; Methotrexate; Middle Aged; Psoriasis; PUVA Therapy; Skin Neoplasms | 1986 |
Uptake of methotrexate linked to polyclonal and monoclonal antimelanoma antibodies by a human melanoma cell line.
Topics: Absorption; Animals; Antibodies, Monoclonal; Binding Sites; Cell Line; Humans; Melanoma; Methotrexate; Rabbits; Skin Neoplasms | 1985 |
Antibodies as carriers of cancer chemotherapeutic agents.
Topics: Animals; Antibodies, Neoplasm; Biological Transport; Female; Immunoglobulin Fab Fragments; Immunoglobulin G; Liposomes; Lymphoma; Melanoma; Methotrexate; Mice; Mice, Inbred C57BL; Pharmaceutical Vehicles | 1985 |
[Adjuvant chemotherapy of intraocular malignant melanoma. Apropos of 20 cases].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dacarbazine; Eye Neoplasms; Female; Humans; Liver Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Procarbazine; Thiotepa; Vinblastine | 1985 |
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Intestinal Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycins; Neoplasms; Palliative Care; Pharyngeal Neoplasms; Sarcoma; Thiotepa; Tongue Neoplasms; Urogenital Neoplasms; Vinblastine | 1971 |
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Imidazoles; Jaw Neoplasms; Mannomustine; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Prognosis; Sarcoma; Thiotepa; Vinblastine | 1973 |
Cutaneous uses of the antiproliferative drugs.
Topics: Administration, Topical; Antimetabolites; Azauridine; Bleomycin; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Humans; Hydroxyurea; Immunotherapy; Melanoma; Methotrexate; Mitosis; Mycosis Fungoides; Organ Specificity; Psoriasis; Skin Neoplasms | 1974 |
Some aspects of the use of cytostatic drugs in dermatology.
Topics: Colchicine; Dactinomycin; Fluorouracil; Humans; Melanoma; Methotrexate; Mycosis Fungoides; Nitrogen Mustard Compounds; Psoriasis; Sarcoma, Kaposi; Skin Neoplasms; Vinblastine | 1966 |
Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck.
Topics: Adenoma, Pleomorphic; Carcinoma, Squamous Cell; Facial Neoplasms; Fibrosarcoma; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Lip Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mechlorethamine; Melanoma; Methotrexate; Mouth Neoplasms; Palatal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1965 |
Treatment of advanced cancer with active immunization.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies; Antigen-Antibody Reactions; Breast Neoplasms; Colonic Neoplasms; gamma-Globulins; Humans; Hypersensitivity; Immunotherapy; Melanoma; Methotrexate; Neoplasms; Rabbits; Rhabdomyosarcoma; Sarcoma; Stomach Neoplasms | 1969 |
[Recent progress in American dermatology].
Topics: Adult; Carcinoma, Basal Cell; Child; Child, Preschool; Dermatitis; Dermatitis, Contact; Dermatomycoses; Drug Eruptions; Female; Gonorrhea; Humans; Infant; Keratosis; Lupus Erythematosus, Systemic; Male; Melanoma; Methotrexate; Pemphigus; Psoriasis; Research; Rothmund-Thomson Syndrome; Sarcoidosis; Skin Diseases; Skin Neoplasms; United States | 1972 |
The metabolic fate of tritiated methotrexate. II. Absorption and excretion in man.
Topics: Adult; Blood; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Child; Child, Preschool; Choriocarcinoma; Chromatography; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Liver Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Pregnancy; Testicular Neoplasms; Tritium; Urine | 1965 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgerminoma; Female; Fibrosarcoma; Humans; Male; Melanoma; Mesothelioma; Methotrexate; Middle Aged; Myxosarcoma; Neoplasms, Connective Tissue; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neurofibromatosis 1; Ovarian Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Uterine Neoplasms | 1968 |
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors.
Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fibrosarcoma; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteosarcoma; Pancreatic Neoplasms; Pharyngeal Neoplasms; Prognosis; Sarcoma; Sarcoma, Synovial; Vincristine | 1969 |
[Proresid-methotrexate combination in chemotherapy of orofacial carcinoma].
Topics: Agranulocytosis; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Humans; Infections; Injections, Intra-Arterial; Leukopenia; Lip Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Tongue Neoplasms | 1970 |
Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Autopsy; Brain Neoplasms; Breast Neoplasms; Cerebral Cortex; Cranial Nerves; Female; Headache; Humans; Injections, Spinal; Intracranial Pressure; Lung Neoplasms; Lymphoma; Male; Melanoma; Meninges; Mental Disorders; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Seeding; Pancreatic Neoplasms; Sarcoma; Spinal Nerve Roots | 1974 |
The treatment of malignant melanoma with cobalt and hyperbaric oxygen.
Topics: Cervical Vertebrae; Cobalt Radioisotopes; Cyclophosphamide; Female; Humans; Hyperbaric Oxygenation; Male; Melanoma; Melphalan; Methotrexate; Middle Aged; Neoplasm Metastasis; Radiography; Radioisotope Teletherapy; Radiotherapy Dosage; Vinblastine | 1974 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine | 1972 |
Cancer chemotherapy. I. Methods, agents and overall results in 400 patients.
Topics: Adenocarcinoma; Amides; Androgens; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Glucocorticoids; Head; Head and Neck Neoplasms; Humans; Imidazoles; Lung Neoplasms; Male; Mechlorethamine; Melanoma; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Progesterone; Rectal Neoplasms; Sarcoma; Thiotepa; Triazenes | 1972 |
[Antineoplastic activity of antibiotic 1719 from the group of diazo compounds].
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Azo Compounds; Carcinoma, Ehrlich Tumor; Female; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Leukemia L1210; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sarcoma 180; Sarcoma 37; Stomach Neoplasms; Time Factors; Vaginal Neoplasms | 1972 |
Malignant melanoma--the treatment of the primary lesion.
Topics: Antineoplastic Agents; Biopsy; Humans; Melanoma; Methotrexate; Neoplasm Metastasis; Skin Neoplasms | 1973 |
Prolonged survival in malignant melanoma of the nose.
Topics: Electrocoagulation; Female; Humans; Melanoma; Methotrexate; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Nose Neoplasms; Time Factors | 1974 |
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Daunorubicin; Fluorouracil; Melanoma; Methotrexate; Mice; Neoplasm Transplantation; Plasmacytoma; Procarbazine; Rats; Thymidine; Tritium; Uridine | 1974 |
[A new combination of methotrexate and folinic acid for cancer treatment (acute leukemia and solid tumors)].
Topics: Agranulocytosis; Antineoplastic Agents; Breast Neoplasms; Female; Hemangiosarcoma; Hodgkin Disease; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Osteosarcoma; Pancreatic Neoplasms; Radiography; Rectal Neoplasms; Rhabdomyosarcoma; Testicular Neoplasms; Thrombocytopenia | 1969 |
Regional chemotherapy of cancer of the head and neck.
Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine | 1966 |
Regional chemotherapeutic perfusion and infusion of brain and face tumors.
Topics: Adenocarcinoma; Ameloblastoma; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Ethylenediamines; Facial Neoplasms; Fibrosarcoma; Glioma; Humans; Infusions, Parenteral; Mechlorethamine; Melanoma; Melphalan; Meningioma; Methotrexate; Osteosarcoma; Perfusion; Quinones; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Thiotepa | 1967 |
[Antineoplastic polychemotherapy in thoracic pathology].
Topics: Adrenalectomy; Aged; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Cortisone; Cyclophosphamide; Drug Synergism; Ethinyl Estradiol; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hydrazines; Hypophysectomy; Kidney Neoplasms; Lung Neoplasms; Male; Melanoma; Melphalan; Mesothelioma; Methotrexate; Middle Aged; Nandrolone; Neoplasm Metastasis; Ovarian Neoplasms; Podophyllin; Sarcoma; Thiotepa; Vinblastine | 1968 |
[Chemotherapy of solid tumors].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Fluorouracil; Humans; Melanoma; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Skin Neoplasms; Thiotepa | 1970 |
[Chemotherapy in the treatment of nevocarcinomas].
Topics: Antineoplastic Agents; Humans; Melanoma; Methotrexate; Remission, Spontaneous; Thiotepa; Vinblastine | 1971 |
Intermittent intravenous methotrexate in the treatment of advanced epidermoid carcinoma.
Topics: Aged; Bronchial Neoplasms; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Male; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Penile Neoplasms; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1972 |
Expectations and pitfalls of chemotherapy in a university cancer clinic.
Topics: Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Hospitals, Teaching; Humans; Lung Neoplasms; Male; Melanoma; Methotrexate; Neoplasms; Outpatient Clinics, Hospital; Sarcoma; South Carolina; Vincristine | 1972 |
Seventy-five cases of solid tumours treated by a modified quadruple chemotherapy regime.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Fluorouracil; Gastrointestinal Neoplasms; Head; Head and Neck Neoplasms; Humans; Infant; Injections, Intravenous; Male; Melanoma; Methotrexate; Middle Aged; Neoplasms; Ovarian Neoplasms; Sarcoma; Testicular Neoplasms; Uterine Cervical Neoplasms; Vincristine | 1971 |
Leptomeningeal metastasis from systemic cancer: a report of 47 cases.
Topics: Brain; Brain Neoplasms; Breast Neoplasms; Humans; Lung Neoplasms; Lymphoma; Melanoma; Meninges; Methotrexate; Neoplasm Metastasis; Neoplasm Seeding | 1971 |
Treatment of disseminated melanoma by systemic melphalan, methotrexate and autogenous bone marrow transplants. Experience with 114 patients.
Topics: Bone Marrow Transplantation; Humans; Melanoma; Melphalan; Methotrexate; Transplantation, Autologous | 1967 |
Local chemotherapy of cutaneous neoplasms.
Topics: Adenocarcinoma; Allergy and Immunology; Antineoplastic Agents; Carcinoma, Squamous Cell; Dactinomycin; Fibrosarcoma; Fluorouracil; Humans; Hypersensitivity; Leukemia; Lymphoma; Melanoma; Methotrexate; Nitrogen Mustard Compounds; Skin Neoplasms; Triaziquone | 1970 |
[Intracranial melanoma].
Topics: Adolescent; Adult; Brain Neoplasms; Carotid Arteries; Chromatophores; Cobalt Isotopes; Craniotomy; Female; Humans; Male; Melanins; Melanoma; Methotrexate; Neoplasm Metastasis; Prognosis; Radiography; Spinal Puncture | 1968 |
Chemotherapy of human cancer transplants with methotrexate (amethopterin) and horse serum.
Topics: Animals; Cortisone; Cricetinae; Female; Horses; Humans; Immunization, Passive; Male; Melanoma; Methotrexate; Neoplasm Transplantation; Neoplasms, Experimental; Thyroid Neoplasms | 1966 |
Infusion chemotherapy in head and neck tumors.
Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Chondrosarcoma; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Melanoma; Methotrexate; Middle Aged; Mouth Neoplasms; Temporal Arteries | 1966 |
Immunologic and chemotherapeutic effects on human melanoma heterotransplant.
Topics: Humans; Immune Sera; Lymphocytes; Melanoma; Methotrexate; Neoplasm Transplantation | 1966 |