Page last updated: 2024-08-25

methotrexate and Lupus Nephritis

methotrexate has been researched along with Lupus Nephritis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (36.84)18.2507
2000's5 (26.32)29.6817
2010's6 (31.58)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Tanaka, Y; Tsujimura, S1
Bertsias, G; Boumpas, DT; Fanouriakis, A; Tziolos, N1
Gladman, DD; Ibañez, D; Touma, Z; Urowitz, MB1
Carter, JD; Patel, AA; Raturi, R1
Koo, YX; Lai, GG; Lim, ST; Tan, TT; Tao, M1
Ikeda, K; Iwadate, H; Kobayashi, H; Ogawa, K; Ohira, H; Watanabe, H; Yano, K1
Alarcón, GS; Alfaro-Lozano, JL; Boggio, G; Cavalcanti, F; Costallat, LT; de la Torre, IG; Del Pozo, MJ; Esteva-Spinetti, MH; Gómez, LA; Guibert-Toledano, M; Hachuel, L; Massardo, L; Pons-Estel, BA; Pons-Estel, GJ; Saurit, V; Silveira, LH; Wojdyla, D1
Brandozzi, G; Danieli, MG; Giangiacomi, M; Malcangi, G; Zampetti, M1
Edelheit, BS; Lehman, TJ; Onel, KB1
Aringer, M; Graninger, WB; Smolen, JS; Steiner, G1
Abud-Mendoza, C; Baranda, L; González-Amaro, R; Hernández-Castro, B; Paredes-Saharopulos, O; Portales-Pérez, D; Vigna-Perez, M1
Ali, Y; Gladman, DD; Ibañez, D; Urowitz, MB1
Bartoli, E; De Vita, S; Ferraccioli, GF1
Dayan, M; Mozes, E; Segal, R; Zinger, H1
Dagenais, P; Gladman, DD; Urowitz, MB; Walz LeBlanc, BA1
Asherson, RA; Hughes, GR; Schatten, S1
Mihara, M; Moriya, Y; Takagi, N; Takeda, Y; Urakawa, K2
González, T; Hernández-Beriaín, JA; Rodríguez-Lozano, B1

Reviews

3 review(s) available for methotrexate and Lupus Nephritis

ArticleYear
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calcineurin Inhibitors; Cardiovascular Diseases; Cyclophosphamide; Disease Management; Female; Glucocorticoids; Heart Valve Diseases; Humans; Hydroxychloroquine; Hypertension, Pulmonary; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lupus Nephritis; Lupus Vasculitis, Central Nervous System; Macrophage Activation Syndrome; Methotrexate; Mycophenolic Acid; Myocarditis; Outcome Assessment, Health Care; Pericarditis; Phenotype; Pregnancy; Pregnancy Complications; Prognosis; Purpura, Thrombocytopenic, Idiopathic; Quality of Life; Recurrence; Rituximab; Severity of Illness Index; Survival Rate; Uterine Cervical Neoplasms

2021
Two cases demonstrating thalidomide's efficacy in refractory lupus nephritis.
    Clinical rheumatology, 2017, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Dapsone; Disease Progression; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Lupus Nephritis; Male; Methotrexate; Mycophenolic Acid; Thalidomide; Treatment Outcome

2017
[New approaches to the therapy of diffuse inflammatory diseases of the connective tissue].
    Medicina clinica, 1991, Oct-05, Volume: 97, Issue:11

    Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Connective Tissue Diseases; Cyclosporine; Drug Therapy, Combination; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymph; Methotrexate; Plasmapheresis; Synovitis

1991

Trials

3 trial(s) available for methotrexate and Lupus Nephritis

ArticleYear
Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study.
    Arthritis research & therapy, 2006, Volume: 8, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Apoptosis; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Lupus Nephritis; Lymphocyte Activation; Male; Methotrexate; Middle Aged; Pilot Projects; Rituximab; T-Lymphocytes

2006
Outcomes in patients with active lupus nephritis requiring immunosuppressives who never received cyclophosphamide.
    The Journal of rheumatology, 2007, Volume: 34, Issue:7

    Topics: Adult; Azathioprine; Cohort Studies; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Lupus Nephritis; Male; Methotrexate; Mycophenolic Acid; Prognosis; Severity of Illness Index; Survival Rate; Treatment Outcome

2007
A novel antifolate, MX-68, inhibits the development of autoimmune disease in MRL/lpr mice.
    International archives of allergy and immunology, 1997, Volume: 113, Issue:4

    Topics: 2-Aminoadipic Acid; Administration, Oral; Animals; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Blood Urea Nitrogen; Cell Division; Cholesterol; DNA, Single-Stranded; Dose-Response Relationship, Drug; Female; Folic Acid Antagonists; Kidney Diseases; Lupus Nephritis; Lymph Nodes; Methotrexate; Mice; Mice, Inbred MRL lpr; Picrates; Proteinuria; Specific Pathogen-Free Organisms; Spleen

1997

Other Studies

13 other study(ies) available for methotrexate and Lupus Nephritis

ArticleYear
Treatment with Methotrexate and Intravenous Cyclophosphamide Pulse Therapy Regulates the P-gp
    Internal medicine (Tokyo, Japan), 2019, Volume: 58, Issue:21

    Topics: Administration, Intravenous; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-Positive T-Lymphocytes; Cyclophosphamide; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infusions, Intravenous; Lupus Nephritis; Methotrexate

2019
Time to recovery from proteinuria in patients with lupus nephritis receiving standard treatment.
    The Journal of rheumatology, 2014, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Cyclosporine; Databases, Factual; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Longitudinal Studies; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Methotrexate; Middle Aged; Ontario; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Proteinuria; Steroids; Time Factors; Treatment Outcome; Urinalysis; Young Adult

2014
Use of rituximab in combination with high-dose methotrexate in the treatment of primary central nervous system lymphoma in a mycophenolate mofetil treated patient with lupus nephritis.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:1

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Central Nervous System Neoplasms; Drug Administration Schedule; Female; Fever; Fungemia; Humans; Immunocompromised Host; Immunosuppressive Agents; Lupus Nephritis; Lymphoma; Methotrexate; Mycophenolic Acid; Neurotoxicity Syndromes; Neutropenia; Rituximab; Treatment Outcome; Young Adult

2011
Therapy-related myelodysplastic syndrome following cyclophosphamide pulse and/or methotrexate therapy in a patient with systemic lupus erythematosus.
    Fukushima journal of medical science, 2010, Volume: 56, Issue:2

    Topics: Adult; Bone Marrow Cells; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Myelodysplastic Syndromes; Pancytopenia

2010
The impact of rural residency on the expression and outcome of systemic lupus erythematosus: data from a multiethnic Latin American cohort.
    Lupus, 2012, Volume: 21, Issue:13

    Topics: Adult; Age Factors; American Indian or Alaska Native; Black People; Chi-Square Distribution; Comorbidity; Cyclophosphamide; Disease Progression; Educational Status; Female; Health Services Accessibility; Healthcare Disparities; Humans; Hypertension; Immunosuppressive Agents; Latin America; Logistic Models; Longitudinal Studies; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Medically Uninsured; Methotrexate; Multivariate Analysis; Odds Ratio; Prognosis; Racial Groups; Renal Dialysis; Residence Characteristics; Risk Factors; Rural Health; Socioeconomic Factors; Time Factors; Urban Health; White People; Young Adult

2012
Bullous SLE: response to methotrexate and relationship with disease activity.
    Lupus, 2003, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Dermatologic Agents; Female; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Skin Diseases, Vesiculobullous

2003
Combined intravenous methotrexate and cyclophosphamide for refractory childhood lupus nephritis.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:3

    Topics: Blood Proteins; Chronic Disease; Complement C3; Creatinine; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Leukopenia; Lupus Nephritis; Methotrexate; Prednisone; Serum Albumin

2004
Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:10

    Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis; Autoantibodies; Azathioprine; Bacteremia; Cardiolipins; Complement System Proteins; DNA; Escherichia coli Infections; Female; Humans; Immunosuppressive Agents; Infliximab; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Middle Aged; Safety; Treatment Outcome; Tumor Necrosis Factor-alpha; Urinary Tract Infections

2004
Methotrexate benefits in patients with lupus with and without nephritis.
    The Journal of rheumatology, 1995, Volume: 22, Issue:7

    Topics: Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate

1995
Methotrexate treatment in murine experimental systemic lupus erythematosus (SLE); clinical benefits associated with cytokine manipulation.
    Clinical and experimental immunology, 1995, Volume: 101, Issue:1

    Topics: Animals; Antibodies, Anti-Idiotypic; Autoantibodies; Cytokines; Female; Immunization; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Mice; Mice, Inbred BALB C

1995
Methotrexate in systemic lupus erythematosus.
    The Journal of rheumatology, 1994, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Arthritis; Female; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Retrospective Studies; Treatment Outcome

1994
Methotrexate in systemic lupus erythematosus.
    The Journal of rheumatology, 1997, Volume: 24, Issue:3

    Topics: Adult; Female; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Prednisone

1997
Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE).
    International journal of immunopharmacology, 1997, Volume: 19, Issue:2

    Topics: 2-Aminoadipic Acid; Age Factors; Animals; Autoantibodies; Blood Urea Nitrogen; Cholesterol; Chronic Disease; Disease Models, Animal; Female; Folic Acid Antagonists; Graft vs Host Disease; Lupus Erythematosus, Systemic; Lupus Nephritis; Methotrexate; Mice; Mice, Inbred DBA; Mice, Inbred NZB; Proteinuria

1997