Page last updated: 2024-08-25

methotrexate and Low Bone Density

methotrexate has been researched along with Low Bone Density in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (42.11)18.2507
2000's4 (21.05)29.6817
2010's6 (31.58)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Bhandari, S; Jain, G; Kalra, S; Vasnik, G1
Aftab, MT; Hassali, MA; Naqvi, AA1
Abrahamsen, B; Andersen, LS; Ellingsen, T; Hansen, I; Hansen, MS; Hetland, ML; Hyldstrup, L; Hørslev-Petersen, K; Jensen, TW; Junker, P; Jurik, AG; Langdahl, B; Lauridsen, UB; Lindegaard, H; Lottenburger, T; Pedersen, JK; Pødenphant, J; Skjødt, H; Stengaard-Petersen, K; Svendsen, AJ; Tarp, U; Vestergaard, A; Zerahn, B; Østergaard, M1
Amano, K; Hatta, K; Kanazawa, T; Kume, K; Kuwaba, N; Ohta, H; Yamada, S1
Engelage, AH; Posthuma, BJ; van der Bijl, AE; van Veen, GJ; Zijlstra, TR1
Conaghan, PG; Emery, P; Haugeberg, G; Morton, S1
Abboud, M; Arabi, A; Chaiban, J; Daouk, LE; El-Hajj Fuleihan, G; Ghalayini, T; Muwakkit, S1
Cool, JC; Fan, CM; Foster, BK; Georgiou, KR; King, TJ; Scherer, MA; Xian, CJ1
Davies, JH; Evans, BA; Gregory, JW; Jenney, ME2
Jones, G; Sambrook, PN1
Dengg, K; Fink, FM; Gassner, I; Meister, B; Streif, W1
Huffer, WE; May, KP; McDermott, MT; West, SG1
May, KP; McDermott, MT; Mercill, D; West, SG1
Bakker, WK; Bos, JD; Dijkstra, PF; Dinant, HJ; van Soesbergen, RM; Zonneveld, IM1
Mizushima, Y; Suzuki, Y1
Náfrádi, L; Toldy, E; Varga, L1
De Klerk, JM; Jacobs, JW; Stevens, H; Van Rijk, PP1
Berg, CL; Gollan, JL1

Reviews

5 review(s) available for methotrexate and Low Bone Density

ArticleYear
Epidemiology of rheumatoid arthritis, clinical aspects and socio-economic determinants in Pakistani patients: A systematic review and meta-analysis.
    JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Cardiovascular Diseases; Comorbidity; Cost of Illness; Depression; Depressive Disorder; Fibromyalgia; Methotrexate; Osteoporosis; Pakistan; Prevalence; Risk Factors; Social Class

2019
Skeletal morbidity in childhood acute lymphoblastic leukaemia.
    Clinical endocrinology, 2005, Volume: 63, Issue:1

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Child; Child, Preschool; Female; Glucocorticoids; Homeostasis; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2005
Drug-induced disorders of bone metabolism. Incidence, management and avoidance.
    Drug safety, 1994, Volume: 10, Issue:6

    Topics: Adrenal Cortex Hormones; Aluminum; Anticonvulsants; Bone Diseases, Metabolic; Calcium; Cyclosporine; Diphosphonates; Fluorides; Heparin; Hormones; Humans; Methotrexate

1994
Osteoporosis in rheumatoid arthritis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1997, Volume: 7 Suppl 3

    Topics: Adrenal Cortex Hormones; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Folic Acid Antagonists; Humans; Menopause; Methotrexate; Middle Aged; Movement; Osteoporosis; Rats; Sex Factors

1997
Primary biliary cirrhosis: new therapeutic directions.
    Scandinavian journal of gastroenterology. Supplement, 1992, Volume: 192

    Topics: Bone Diseases, Metabolic; Humans; Hypercholesterolemia; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Pruritus; Ursodeoxycholic Acid

1992

Trials

5 trial(s) available for methotrexate and Low Bone Density

ArticleYear
Periarticular and generalised bone loss in patients with early rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial.
    Annals of the rheumatic diseases, 2014, Volume: 73, Issue:6

    Topics: Adult; Aged; Alendronate; Antirheumatic Agents; Arthritis, Rheumatoid; Betamethasone; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Resorption; Cyclosporine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Injections, Intra-Articular; Lumbar Vertebrae; Male; Methotrexate; Middle Aged; Radiography; Treatment Outcome; Young Adult

2014
The effect of tocilizumab on bone mineral density in patients with methotrexate-resistant active rheumatoid arthritis.
    Rheumatology (Oxford, England), 2014, Volume: 53, Issue:5

    Topics: Absorptiometry, Photon; Adult; Aged; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Bone Density; Bone Diseases, Metabolic; Drug Resistance; Female; Femur Neck; Humans; Interleukin-6; Lumbar Vertebrae; Male; Methotrexate; Middle Aged; Prospective Studies; Severity of Illness Index; Treatment Outcome

2014
Effect of intra-articular corticosteroid injections and inflammation on periarticular and generalised bone loss in early rheumatoid arthritis.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:1

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Density; Bone Diseases, Metabolic; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Injections, Intra-Articular; Male; Metacarpophalangeal Joint; Methotrexate; Methylprednisolone; Middle Aged; Treatment Outcome

2011
Methotrexate osteopathy in infants with tumors of the central nervous system.
    Medical and pediatric oncology, 1994, Volume: 23, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Diseases, Metabolic; Brain Neoplasms; Calcification, Physiologic; Child, Preschool; Combined Modality Therapy; Ependymoma; Female; Follow-Up Studies; Fractures, Bone; Humans; Infant; Infratentorial Neoplasms; Male; Medulloblastoma; Methotrexate

1994
[Measure of bone loss in rheumatoid arthritis].
    Orvosi hetilap, 1999, Feb-07, Volume: 140, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Densitometry; Female; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal

1999

Other Studies

9 other study(ies) available for methotrexate and Low Bone Density

ArticleYear
Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease.
    BMJ case reports, 2020, Jun-01, Volume: 13, Issue:6

    Topics: Absorptiometry, Photon; Acidosis, Renal Tubular; Adolescent; Antirheumatic Agents; Arthralgia; Bone and Bones; Bone Diseases, Metabolic; Female; Humans; Hydroxychloroquine; Hypokalemia; Immunologic Tests; Methotrexate; Mobility Limitation; Prednisolone; Sjogren's Syndrome; Treatment Outcome; Urinalysis

2020
[Three patients with a fracture during methotrexate use, possibly due to methotrexate osteopathy].
    Nederlands tijdschrift voor geneeskunde, 2008, Oct-25, Volume: 152, Issue:43

    Topics: Aged; Bone Diseases, Metabolic; Female; Fractures, Stress; Humans; Immunosuppressive Agents; Inflammation; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteoporosis; Remission, Spontaneous

2008
Predictors of bone loss in childhood hematologic malignancies: a prospective study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012, Volume: 23, Issue:2

    Topics: Absorptiometry, Photon; Age Factors; Anthropometry; Body Mass Index; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Child; Child, Preschool; Dexamethasone; Epidemiologic Methods; Female; Glucocorticoids; Hematologic Neoplasms; Hip Joint; Humans; Life Style; Lumbar Vertebrae; Male; Methotrexate; Parathyroid Hormone; Vitamin D

2012
Methotrexate chemotherapy reduces osteogenesis but increases adipogenic potential in the bone marrow.
    Journal of cellular physiology, 2012, Volume: 227, Issue:3

    Topics: Adipocytes; Adipogenesis; Animals; Antimetabolites, Antineoplastic; Bone Diseases, Metabolic; Bone Marrow Cells; Cell Differentiation; Disease Models, Animal; Male; Methotrexate; Osteogenesis; Rats; Rats, Sprague-Dawley; Stem Cells

2012
The effect of low-dose methotrexate on bone metabolism and histomorphometry in rats.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:2

    Topics: Animals; Blood; Bone and Bones; Bone Diseases, Metabolic; Calcium; Dose-Response Relationship, Drug; Female; Femur; Methotrexate; Ovariectomy; Rats; Rats, Sprague-Dawley; Urine

1994
The effect of methotrexate on mouse bone cells in culture.
    Arthritis and rheumatism, 1996, Volume: 39, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Bone Diseases, Metabolic; Calcium; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Female; Methotrexate; Mice; Mice, Inbred ICR; Osteoblasts; Osteoclasts; Pregnancy; Skull

1996
Methotrexate osteopathy in long-term, low-dose methotrexate treatment for psoriasis and rheumatoid arthritis.
    Archives of dermatology, 1996, Volume: 132, Issue:2

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Female; Fractures, Stress; Humans; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Osteoporosis; Psoriasis; Radiography

1996
Methotrexate osteopathy demonstrated by Technetium-99m HDP bone scintigraphy.
    Clinical nuclear medicine, 2001, Volume: 26, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Humans; Male; Methotrexate; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Tibia

2001
In vitro effects of chemotherapeutic agents on human osteoblast-like cells.
    Calcified tissue international, 2002, Volume: 70, Issue:5

    Topics: Alkaline Phosphatase; Asparaginase; Bone Diseases, Metabolic; Cell Count; Cell Culture Techniques; Cell Differentiation; Dexamethasone; Etoposide; Humans; Methotrexate; Osteoblasts; Vincristine

2002