Page last updated: 2024-08-25

methotrexate and Liver Steatosis

methotrexate has been researched along with Liver Steatosis in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199018 (54.55)18.7374
1990's0 (0.00)18.2507
2000's4 (12.12)29.6817
2010's11 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chonprasertsuk, S; Lertnawapan, R; Siramolpiwat, S1
Pais, R; Ratziu, V; Rusu, E1
Amacher, DE; Chalasani, N1
Collins, P; Higgins, E; Kirby, B; Lally, A; Lynch, M; McCormick, PA; Nolan, N; Omar, H; Rogers, S; Vellinga, A1
Büning, J; Fellermann, K; Lehnert, H; Mackenroth, T; Möller, S; Olsen, V; Schmidt, KJ; Schröder, T; Sina, C1
Vinken, M1
Guo, GL; Schumacher, JD1
Ferrazzi, A; Girolomoni, G; Gisondi, P1
Aghdassi, E; Fortin, PR; Gladman, DD; Hirschfield, GM; Huang, D; Mosko, J; Su, J; Urowitz, MB1
Larrain, S; Rinella, ME1
Abritta, G; Cravero, A; Enriquez, N; Martínez Artola, Y; Ortiz, V; Palermo, C; Poncino, D; Rosenberg, S; Santiago García, D; Saturansky, E1
Campbell, MS; Reddy, KR1
Burt, AD; Leong, MY; Mathew, J; Morley, N1
Flechtenmacher, C; Longerich, T; Schirmacher, P1
Chung, H; Hong, I; Kang, KS; Kim, HL; Kim, JH; Kim, M; Kong, G; Lee, BH; Lee, MH; Lee, MO; Yoon, BI1
Zimmerman, HJ2
Allen, RM; Bloomer, JR; Klatskin, G; Kobayashi, K1
Custer, RP; Freeman-Narrod, M; Narrod, SA2
Clegg, DO; Furst, DE; Pogue, R; Tolman, KG1
Aponte, J; Petrelli, M1
Kollberg, B; Sandstedt, B; Szanto, E1
Mackenzie, AH1
Sogaard, H; Zachariae, H1
Kirchmayer, S1
Aach, RD; Eisen, AZ; Grisham, JW; Reese, LT1
Tashima, CK1
Dabels, J; Diwok, K; Leithäuser, W; Moldenhauer, E; Nowotny, P1
Akerman, M; Berge, G; Lundquist, A; Rorsman, H1
Holst, R; Mobacken, H1
Cox, JW; Frost, P; Kalser, M; Millard, MM; Suringa, DW; Weinstein, GD1
Dahl, MG; Gregory, MM; Scheuer, PJ1

Reviews

9 review(s) available for methotrexate and Liver Steatosis

ArticleYear
The impact of obesity and metabolic syndrome on chronic hepatitis B and drug-induced liver disease.
    Clinics in liver disease, 2014, Volume: 18, Issue:1

    Topics: Acetaminophen; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Insulin Resistance; Male; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Prevalence; Risk Factors; Trans-Activators; Viral Regulatory and Accessory Proteins

2014
Drug-induced hepatic steatosis.
    Seminars in liver disease, 2014, Volume: 34, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Retroviral Agents; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Hormonal; Drug Evaluation, Preclinical; Fatty Liver; Humans; Immunosuppressive Agents; Lysosomal Storage Diseases; Methotrexate; Mitochondria, Liver; Phospholipids; Tamoxifen; Valproic Acid

2014
Adverse Outcome Pathways and Drug-Induced Liver Injury Testing.
    Chemical research in toxicology, 2015, Jul-20, Volume: 28, Issue:7

    Topics: Bosentan; Chemical and Drug Induced Liver Injury; Cholestasis; Fatty Liver; Humans; Liver Cirrhosis; Methotrexate; Quantitative Structure-Activity Relationship; Sulfonamides; Valproic Acid

2015
Mechanistic review of drug-induced steatohepatitis.
    Toxicology and applied pharmacology, 2015, Nov-15, Volume: 289, Issue:1

    Topics: Amiodarone; Animals; Camptothecin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Irinotecan; Lipid Metabolism; Liver; Methotrexate; Mitochondria, Liver; Organoplatinum Compounds; Oxaliplatin; Perhexiline; Tamoxifen; Tetracycline; Valproic Acid

2015
Metabolic comorbidities and psoriasis.
    Acta dermatovenerologica Croatica : ADC, 2010, Volume: 18, Issue:4

    Topics: Arthritis, Psoriatic; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Dyslipidemias; Fatty Liver; Humans; Hypertriglyceridemia; Immunosuppressive Agents; Insulin Resistance; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Obesity; Psoriasis; Risk Factors

2010
A myriad of pathways to NASH.
    Clinics in liver disease, 2012, Volume: 16, Issue:3

    Topics: Amiodarone; Anti-Retroviral Agents; Bacterial Infections; Cannabis; Diet; Fatty Liver; Genetic Diseases, Inborn; Glucocorticoids; Humans; Hypothyroidism; Insulin Resistance; Intestinal Diseases; Lipid Metabolism; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Occupational Diseases; Perhexiline

2012
Review article: the evolving role of liver biopsy.
    Alimentary pharmacology & therapeutics, 2004, Aug-01, Volume: 20, Issue:3

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Hepatitis B; Hepatitis C; Humans; Liver; Methotrexate

2004
[Quality and quantity in hepatopathology. Diagnostic and clinically relevant grading for non-tumourous liver diseases].
    Der Pathologe, 2008, Volume: 29, Issue:1

    Topics: Fatty Liver; Female; Humans; Liver; Liver Diseases; Liver Transplantation; Male; Methotrexate; Necrosis

2008
Drug-induced chronic hepatic disease.
    The Medical clinics of North America, 1979, Volume: 63, Issue:3

    Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chronic Disease; Fatty Liver; Hemangioendothelioma; Hexestrol; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate; Necrosis; Oxyphenisatin Acetate

1979

Other Studies

24 other study(ies) available for methotrexate and Liver Steatosis

ArticleYear
Association between cumulative methotrexate dose, non-invasive scoring system and hepatic fibrosis detected by Fibroscan in rheumatoid arthritis patients receiving methotrexate.
    International journal of rheumatic diseases, 2019, Volume: 22, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Elasticity Imaging Techniques; Fatty Liver; Female; Humans; Liver Cirrhosis; Male; Metabolic Syndrome; Methotrexate; Middle Aged; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2019
The use of transient elastography and FibroTest for monitoring hepatotoxicity in patients receiving methotrexate for psoriasis.
    JAMA dermatology, 2014, Volume: 150, Issue:8

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Biopsy; Body Mass Index; Chemical and Drug Induced Liver Injury; Drug Monitoring; Elasticity Imaging Techniques; Fatty Liver; Female; Fibrosis; Humans; Immunosuppressive Agents; Liver; Male; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis; Young Adult

2014
Liver steatosis is a risk factor for hepatotoxicity in patients with inflammatory bowel disease under immunosuppressive treatment.
    European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Azathioprine; Body Mass Index; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Crohn Disease; Fatty Liver; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Sex Factors; Ultrasonography; Young Adult

2015
Prevalence and risk factors for liver biochemical abnormalities in Canadian patients with systemic lupus erythematosus.
    The Journal of rheumatology, 2012, Volume: 39, Issue:2

    Topics: Adult; Alanine Transaminase; Antibodies, Neutralizing; Antiphospholipid Syndrome; Aspartate Aminotransferases; Autoimmune Diseases; Azathioprine; Body Mass Index; Canada; DNA; Fatty Liver; Female; Humans; Hypertension; Immunosuppressive Agents; Liver; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Prevalence; Risk Factors; Severity of Illness Index; Ultrasonography

2012
[Liver diseases in rheumatoid and psoriatic arthritis].
    Acta gastroenterologica Latinoamericana, 2012, Volume: 42, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cohort Studies; Cross-Sectional Studies; Fatty Liver; Female; Humans; Male; Methotrexate; Middle Aged; Obesity; Risk Factors

2012
A liver fibrosis cocktail? Psoriasis, methotrexate and genetic hemochromatosis.
    BMC dermatology, 2005, Nov-29, Volume: 5

    Topics: Dermatologic Agents; Fatty Liver; Fibrosis; Hemochromatosis; Humans; Liver; Male; Methotrexate; Middle Aged; Psoriasis; Risk Factors

2005
Gene expression profiles of murine fatty liver induced by the administration of methotrexate.
    Toxicology, 2008, Jul-10, Volume: 249, Issue:1

    Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Liver; Gene Expression; Gene Expression Profiling; Lipid Metabolism; Male; Methotrexate; Mice; Mice, Inbred ICR; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Toxicogenetics

2008
Enzymatic fluorometry for estimating serum total bile acid concentration.
    JAMA, 1979, May-11, Volume: 241, Issue:19

    Topics: 3-Hydroxysteroid Dehydrogenases; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Fasting; Fatty Liver; Female; Fluorometry; Hepatitis, Viral, Human; Humans; Liver; Liver Diseases; Male; Methotrexate; Necrosis; Sarcoidosis

1979
Hepatotoxicity in Wistar rats following chronic methotrexate administration: a model of human reaction.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4

    Topics: Age Factors; Animals; Body Weight; Bone Marrow; Digestive System; Fatty Liver; Humans; Liver; Lung; Lymphocytes; Male; Methotrexate; Necrosis; Rats; Skin; Spleen; Testis; Triglycerides

1977
Chronic toxicity of methotrexate in rats: partial to complete projection of the liver by choline: Brief communication.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:3

    Topics: Animals; Bone Marrow; Choline; Choline Deficiency; Fatty Liver; Liver; Male; Methotrexate; Rats

1977
Liver disease caused by medicinal agents.
    The Medical clinics of North America, 1975, Volume: 59, Issue:4

    Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contraceptive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Halothane; Humans; Isoniazid; Jaundice; Liver; Liver Cirrhosis; Metabolism, Inborn Errors; Methotrexate; Methoxyflurane; Methyldopa; Necrosis; Novobiocin

1975
Acute, reversible hepatic failure associated with methotrexate treatment of rheumatoid arthritis.
    The Journal of rheumatology, 1989, Volume: 16, Issue:8

    Topics: Adult; Arthritis, Rheumatoid; Ascites; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Female; Hepatitis, Chronic; Humans; Liver Cirrhosis; Methotrexate; Middle Aged

1989
Histopathologic findings in the liver of rheumatoid arthritis patients treated with long-term bolus methotrexate.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Time Factors

1988
Hepatotoxicity associated with low-dose, long-term methotrexate treatment of rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1987, Volume: 16, Issue:4

    Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Middle Aged; Time Factors

1987
Hepatotoxicity of prolonged methotrexate therapy for rheumatoid arthritis.
    Cleveland Clinic quarterly, 1985,Summer, Volume: 52, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Methotrexate; Middle Aged; Sjogren's Syndrome

1985
Liver biopsy in psoriasis. A controlled study.
    Dermatologica, 1973, Volume: 146, Issue:3

    Topics: Administration, Oral; Alcoholism; Biopsy; Fatty Liver; Humans; Injections; Liver; Methotrexate; Psoriasis

1973
[Drug-induced hepatopathies].
    Polskie Archiwum Medycyny Wewnetrznej, 1974, Volume: 51, Issue:5

    Topics: Adult; Age Factors; Bilirubin; Cell Membrane; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Female; Halothane; Humans; Infant, Newborn; Liver; Liver Cirrhosis; Male; Methotrexate; Microsomes, Liver; Pharmaceutical Preparations; Pregnancy; Tetracycline

1974
Effects of methotrexate on the liver in psoriasis.
    The Journal of investigative dermatology, 1974, Volume: 62, Issue:6

    Topics: Biopsy; Cell Nucleus; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Follow-Up Studies; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Necrosis; Psoriasis; Sulfobromophthalein

1974
Methotrexate and hepatic disease.
    JAMA, 1971, Jun-21, Volume: 216, Issue:12

    Topics: Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Methotrexate; Psoriasis

1971
[Liver changes in psoriasis vulgaris].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1971, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein

1971
Liver biopsy in psoriasis.
    The British journal of dermatology, 1970, Volume: 82, Issue:3

    Topics: Adult; Aged; Alcoholism; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Methotrexate; Middle Aged; Obesity; Psoriasis; Transaminases

1970
[Liver damage during methotrexate treatment of psoriasis].
    Nordisk medicin, 1970, Sep-17, Volume: 84, Issue:38

    Topics: Adult; Biopsy; Fatty Liver; Female; Humans; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Time Factors

1970
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.
    Archives of dermatology, 1970, Volume: 102, Issue:6

    Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methotrexate; Middle Aged; Necrosis; Psoriasis; Sulfobromophthalein

1970
Liver damage due to methotrexate in patients with psoriasis.
    British medical journal, 1971, Mar-20, Volume: 1, Issue:5750

    Topics: Adult; Aged; Biopsy; Cell Nucleus; Fatty Liver; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Methotrexate; Middle Aged; Psoriasis; Sulfobromophthalein

1971