methotrexate has been researched along with Liver Neoplasms in 333 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 165 (49.55) | 18.7374 |
| 1990's | 70 (21.02) | 18.2507 |
| 2000's | 56 (16.82) | 29.6817 |
| 2010's | 34 (10.21) | 24.3611 |
| 2020's | 8 (2.40) | 2.80 |
| Authors | Studies |
|---|---|
| Duch, D; Ferone, R; Galivan, J; Gaumont, Y; Jones, C; Kisliuk, RL; Maley, F; Nair, MG; Patil, SD | 1 |
| Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M | 1 |
| Chen, X; Feng, J; Gao, P; Jia, W; Li, Z; Lu, H; Shen, S; Sun, L; Suo, C; Wang, Y; Wei, H; Yuan, M; Zhang, H; Zhong, X | 1 |
| Chayama, K; Fujitaka, K; Hamada, H; Hattori, N; Horimasu, Y; Ito, N; Iwamoto, H; Masuda, T; Miyamoto, S; Nakashima, T; Sakamoto, S; Yamaguchi, K | 1 |
| Jiang, J; Lai, L; Liu, X; Sun, B; Wang, X; Xiong, J; Yao, Y; Zhang, X | 1 |
| Chen, M; He, B; Jiang, Y; Li, N; Li, Z; Liu, Q; Ma, J; Wang, W | 1 |
| Iwaki, N; Kurokawa, T; Maeda, Y; Mochizuki, K; Ozaki, J | 1 |
| Abdel-Moneim, AM; Alfwuaires, M; Algefare, AI; Elmenshawy, OM; Elsawy, H; Khalil, M; Sedky, A | 1 |
| Inoue, J; Iwata, T; Kakazu, E; Masamune, A; Ninomiya, M; Sano, A; Tsuruoka, M | 1 |
| Asakuma, J; Asano, T; Hamada, S; Horiguchi, A; Ito, K; Kanbara, T; Tasaki, S; Tsujita, Y; Yoshii, H | 1 |
| Cai, H; Cao, K; Chen, Z; Li, W; Liu, X; Wang, J; Wu, L; Zhao, J | 1 |
| Eso, Y; Marusawa, H; Mimori, T; Mishima, M; Morita, M; Sawada, K; Seno, H; Takahashi, K; Takai, A; Ueda, Y; Yoshiji, S | 1 |
| Apolo, AB; Chowdhury, S; Galsky, MD; Hahn, NM; Merseburger, AS; Milowsky, MI; Petrylak, D; Powles, T; Quinn, DI; Rosenberg, JE; Siefker-Radtke, A; Sonpavde, G; Sternberg, CN | 1 |
| Hashimoto, A; Ikenaka, T; Kakutani, T; Kawasaki, Y; Kodama, K; Matsui, T; Nogi, S; Nunokawa, T; Ogihara, H; Saito, I; Tominaga, A; Tsuno, H; Watai, K | 1 |
| Funakoshi, K; Takahashi, K; Terai, S; Watanabe, S | 1 |
| Ahn, SE; Choi, HY; Lee, KM; Park, JE; You, MW | 1 |
| Inoue, Y; Iwaki, M; Kawase, A; Koizumi, E; Nakazaki, S | 1 |
| Ford, B; Kobayashi, T; Sekar, P | 1 |
| Bhat, MK; Kumari, R; Meena, AS; Mohammad, N; Sharma, A; Singh, SV | 1 |
| Aplenc, R; Chiusolo, P; Coenen, MJ; De Mattei, M; Gemmati, D; Hagleitner, MM; Hoogerbrugge, PM; Krajinovic, M; Ongaro, A; Patiño-Garcia, A; te Loo, DM; Vermeulen, SH | 1 |
| Chen, H; Li, R; Liu, Y; Wang, Y; Wu, J; Yang, X; Zhang, N; Zhou, P | 1 |
| Aikawa, M; Koyama, I; Miyazawa, M; Okada, K; Okamoto, K; Toshimitsu, Y; Ueno, Y; Yamaguchi, S | 1 |
| Hayashi, S; Miyazawa, M; Nishikawa, T; Oguri, H | 1 |
| Chang, WJ; Chen, JN; Chou, PL; Hung, YT; Wei, CW; Yiang, GT; Yu, YL | 1 |
| An, T; Liu, Y; Sun, D; Wang, Y; Zhang, C; Zhang, N; Zhou, P | 1 |
| Ahmad, S; Ahmed, M; Al-Badawi, IA; Al-Hashem, H; Al-Hayli, S; Al-Husaini, H; Darwish, A; Edesa, W; Elghamry, W; Elhassan, T; Eltigani, A; Madkhali, I; Omar, A; Soudy, H | 1 |
| Abe, S; Harada, M; Hayashi, T; Hiura, M; Miyagawa, K; Noguchi, H; Oe, S; Shibata, M | 1 |
| Chen, YY; Chiang, PH; Hsieh, MC; Huang, CH; Rau, KM; Su, YL | 1 |
| Chuma, M; Doba, N; Fukuda, H; Hara, K; Ishii, Y; Maeda, S; Matsumoto, R; Nozaki, A; Numata, K; Tanaka, K | 1 |
| Chaudhuri, AS; Fan, Y; Huo, M; Qi, X; Wu, Z; Yuan, S; Zhao, M | 1 |
| Chang, SK; Choi, CH; Do, JH; Kim, HJ; Kim, JG; Kim, JW; Kim, MK; Lee, HW; Lee, SH; Mun, JS; Oh, HC | 1 |
| Bais, EM; de Vries, RR; Horenblas, S; Meinhardt, W; Nieuwenhuijzen, JA | 1 |
| Behnamfar, F; Mousavi, SA | 1 |
| Buwalda, B; Konsman, JP; Koolhaas, JM; Pourtau, L; Schagen, SB; Seigers, R; van Dam, FS | 1 |
| Azad, A; Chionh, F; Jayarajan, J | 1 |
| Bengrine-Lefevre, L; Chouaid, C; Olezac, AS; Papanikolaou, I | 1 |
| Abdelaziz, NN; Abdelhafeez, ZM; Essa, AE; Gado, NM; Kamel, TH; Salem, DA | 1 |
| Otake, T; Takenoshita, S; Watanabe, K; Yasuda, M | 1 |
| Chishima, T; Hasegawa, S; Ichikawa, Y; Ishikawa, T; Shimizu, D | 1 |
| Hata, K; Hirai, I; Maebeya, S; Miki, Y; Oota, F; Tanaka, T; Tanino, H | 1 |
| Gong, R; Meng, X; Xiong, M; Zhong, X | 1 |
| Fujisawa, M; Miyake, H; Muramaki, M; Takenaka, A; Terakawa, T | 1 |
| Liskova, S; Mardiak, J; Mego, M; Obertova, J; Palacka, P; Porsok, S; Rajec, J; Sycova-Mila, Z | 1 |
| Cyriac, S; Rajendranath, R; Sagar, TG; Sridevi, V | 1 |
| Chen, X; Hu, M; Jiang, X; Lin, Z; Ma, Y; Wang, Q; Wang, Y; Xia, H; Yang, Y | 1 |
| de Heij, T; de Jong, DJ; de Vries, HS; Peters, WH; Roelofs, HM; te Morsche, RH | 1 |
| Abotouk, N; Halim, A | 1 |
| Suzuki, Y | 1 |
| Feng, ZH; Huang, B; Katirai, F; Li, D; Liu, J; Lv, M; Ma, J; Shen, GX; Tang, K; Xu, P; Ye, D; Zhang, G; Zhang, H; Zhang, Y | 1 |
| Deschatrette, J; Ng-Bonaventure, K; Philippe, L; Wolfrom, C | 1 |
| Davis, GL; Keeffe, EB | 1 |
| Hata, Y; Itoh, T; Maeda, Y; Matsuoka, S; Nakajima, N; Osada, T; Sano, F | 1 |
| Kuang, A; Liang, Z; Ou, X; Peng, X; Zhong, Y | 1 |
| Emi, Y; Kakeji, Y; Kimura, Y; Maehara, Y; Sakurai, M; Takahashi, I; Yonemura, Y | 1 |
| Baba, Y; Hayashi, S; Ishikawa, T; Kamimura, T; Nomura, K; Oota, H; Yoshida, T | 1 |
| ADAMSON, RH; LOO, TL; MORRIS, HP | 1 |
| NORCROSS, JW; SULLIVAN, RD; WATKINS, E | 1 |
| CHANDLER, JJ; DONALDSON, SS; FLETCHER, WS | 1 |
| SULLIVAN, RD; WATKINS, E | 1 |
| BOWDEN, L | 1 |
| KIRKHAM, JS | 1 |
| GREENSPAN, EM | 1 |
| BOLANDE, RP; SMITH, JC | 1 |
| NIXON, HH | 1 |
| MORSE, PA; POTTER, VR | 1 |
| GEBERT, R; GENTRY, GA; IVES, DH; MORSE, PA; POTTER, VR | 1 |
| ROTHENBERG, SP | 1 |
| Danno, M; Dono, K; Hatanaka, T; Hayashi, T; Iijima, S; Kato, T; Kikkawa, N; Kurokawa, E; Monden, M; Nagano, H; Nakamori, S; Naoi, Y; Ohshima, S; Sakon, M; Tsujie, M; Umeshita, K; Yamamoto, H | 1 |
| Khoo, SK | 1 |
| Deguchi, T; Ehara, H; Ishihara, S; Masue, T; Mizutani, K; Seike, K; Sugawara, T; Takahashi, Y; Yokoi, S | 1 |
| Arai, Y; Habuchi, T; Horikawa, Y; Hoshi, S; Inoue, T; Kato, T; Matsuura, S; Ohyama, C; Saito, S; Sato, K; Satoh, S; Togashi, H; Tsuchiya, N | 1 |
| Arai, K; Ema, T; Iwasaki, Y; Katayanagi, S; Maeda, Y; Takahashi, K; Takahashi, T; Yamaguchi, T | 1 |
| Kuang, AR; Liang, ZL; Ou, XH; Peng, X; Zhong, YG | 1 |
| Barni, S; Belvedere, O; Beretta, GD; Frontini, L; Grossi, F; Guglielmi, A; Labianca, R; Pella, N; Puglisi, F; Sobrero, A; Zaniboni, A | 1 |
| Deschatrette, J; Guerroui, S; Wolfrom, C | 1 |
| Goldman, ID; Hanscom, M; Zhao, R | 1 |
| Brodsky, I; Rosenbluth, JZ; Styler, MJ; Zak, D | 1 |
| Hamada, T; Ichimura, W; Minagawa, N; Mino, K; Naito, H; Orimo, T; Shibazaki, W; Shinohara, T | 1 |
| Kemeny, NE; Leonard, GD | 1 |
| Arrestier, S; Bouloudian, S; Dubost, JJ; Ristori, JM; Soubrier, M | 1 |
| Debono, D; Malani, AK; Olofsson, B | 1 |
| Amikura, T; Aoki, Y; Banzai, C; Nishikawa, N; Sekine, M; Suzuki, M; Tanaka, K; Yokoo, T | 1 |
| Cheng, BB; Gu, W; Han, J; Li, B; Ling, CQ; Zhang, YN | 1 |
| Ansink, AC; Grootfaam, D; Lok, CA; ten Kate-Booij, MJ; van der Velden, J; Verheijen, RH | 1 |
| Bonutti, A; Cossaro, M; Di Loreto, C; Intini, S; Noce, L; Pecile, P; Saro, F; Terrosu, G | 1 |
| Leenstra, S; Majoie, CB; Richel, DJ; Terheggen, F; Troost, D | 1 |
| Balduzzi, A; Cardillo, A; Colleoni, M; Ghisini, R; Goldhirsch, A; Orlando, L; Peruzzotti, G; Pietri, E; Rocca, A; Torrisi, R | 1 |
| Carrato Mena, A; Guillén Ponce, C; Maciá Escalante, S; Martínez Banaclocha, N; Pons Sanz, V; Rodríguez Lescure, A | 1 |
| Chen, J; Deng, CM; Li, GY; Su, XS; Xiao, XQ | 1 |
| Ling, MT; Wang, X; Wong, YC; Zhang, X | 1 |
| Amaddeo, P; Barbaglio, A; Faldi, F; Fontana, S; Ghilardi, R; Pericotti, S | 1 |
| Chen, L; Fan, Y; Fu, L; Guo, XJ; Lang, RG; Sun, YL | 1 |
| Gill, DS; Hawley, CM; Marlton, PV; Norris, D; Tey, SK | 1 |
| Miyachi, Y; Nakashima, C; Takahashi, K; Tanioka, M | 1 |
| Ariel, IM; Pack, GT | 1 |
| Hocking, DR | 1 |
| Bahendeka, S; Katongole-Mbidde, E; Kyalwazi, SK; Mugerwa, J; Olweny, CL; Otim, D | 1 |
| Harder, M; Limacher, F | 1 |
| Stockert, RJ; Wu, CH; Wu, GY | 1 |
| Choi, TK; Lee, NW; Wong, J | 1 |
| Markman, M | 1 |
| Galivan, J; Samsonoff, W; Tarentino, A | 1 |
| Dannaher, CL; Tamburro, CH; Yam, LT | 1 |
| Bunn, PA; Carney, DN; Cohen, MH; Ihde, DC; Makuch, RW; Matthews, MJ; Minna, JD | 1 |
| Nixon, DW; Shlaer, SM | 1 |
| Donehower, RC; Eddy, JL; Ihde, DC; Myers, CE; Tester, WJ | 1 |
| Fonseca, LS; Hunter, JT; Rapp, HJ; Shu, S | 1 |
| Friedman, MA | 1 |
| Abel, U; Beyer, JH; Herrmann, R; Holzmann, K; Schmieder, A; Spehn, J; von Franqué, U | 1 |
| Carpenter, J; Fishkin, E; Krauss, S; Moore, MR; Raab, S; Raney, M; Smalley, RV; Stagg, M; Velez-Garcia, E; Vogel, CL | 1 |
| Cadman, EC; Cross, J; Glick, JH; Horton, J; Taylor, SG | 1 |
| Colby, TV; Coleman, CN; Cox, RS; Horning, SJ; Rosenberg, SA; Tseng, A; Turner, RR | 1 |
| Aigner, K; Breithaupt, H; Hechtel, R | 1 |
| Aigner, K; Hechtel, R; Merker, G; Schwemmle, K; Tonn, J; Walther, H; Wenzl, A | 1 |
| Aigner, K; Helling, HJ; Krahl, M; Merker, G | 1 |
| Barnard, D; Degefu, S; Eisenman, E; Lacey, CG; Witty, JB | 1 |
| Bang, G; Dahl, O; Engedal, H; Gøthlin, J; Lunde, OD; Mella, O | 1 |
| Brodie, GN; Fox, RM; Levi, JA; Tattersall, MH; Woods, RL | 1 |
| Berenzweig, M; Kaplan, BH; Lanham, R; Richard, J; Solan, A; Vogl, SE | 1 |
| Axelrod, J; Boyce, J; Ertüngealp, E; Sedlis, A; Stanek, A | 1 |
| Friedman, MA; Phillips, TL; Resser, KJ; Volberding, PA | 1 |
| Ariel, IM; Padula, G | 1 |
| Fortune, DW; Hillcoat, BL; McNaughton, WM; Ostör, AG; Riley, CB; Rischin, D | 1 |
| Adler, GK; Arbiser, JL; Arbiser, ZK; Majzoub, JA; Martinez, C; Rosen, LB | 1 |
| Ciaccia, D; Corey, GR; Peters, W; Thel, MC; Vredenburgh, JJ | 1 |
| Gabizon, AA; Gorodetsky, R; Mou, X; Vexler, AM | 1 |
| Itakura, M; Kobayashi, F; Matsuzaki, S; Muramatsu, C; Onami, S; Sato, T; Shiraishi, K; Simamura, K; Watanabe, M | 1 |
| Adachi, S; Chikamori, F; Fukao, K; Ishikawa, A; Nozue, M; Otsuka, M; Shibuya, S; Todoroki, T; Yuzawa, K | 1 |
| Callans, LS; Jardines, L; Torosian, MH | 1 |
| Hu, JL; Qi, CQ; Su, J; Zhen, YC | 1 |
| Kennedy, BJ; Kiang, DT; Korzun, AH; Nowak, BS; Perry, MC; Schilling, A; Wood, W; Younger, J | 1 |
| Flintoff, WF; Williams, FM | 1 |
| Hamanaka, Y; Hazama, S; Oka, M; Suzuki, T; Tangoku, A; Tsurumi, M | 1 |
| Goldstein, RB; Zackheim, HS | 1 |
| Moertel, CG | 1 |
| Greco, FA; Hainsworth, JD; Johnson, DH; Lamar, RE; Murphy, PB | 1 |
| Balaban, EP; Bull, J; Frenkel, EP; Graham, M; Periman, P; Perkins, S; Pruitt, B; Ross, M; Ruud, C; Sheehan, RG | 1 |
| Akiyama, T; Kiriyama, M; Kita, I; Kosaka, T; Nakagawa, T; Nakano, Y; Saito, H; Takano, Y; Takashima, S; Tomita, F | 1 |
| Amer, M; Bakri, YN; Ezzat, A; Jabbar, FA; Sinner, W; Subhi, J; Tweijry, A | 1 |
| Iida, A; Ikeda, N; Komatsu, T; Ookubo, K | 1 |
| Adachi, A; Nakano, Y; Ota, Y; Shirafuji, T; Yamaguchi, H; Yoshida, K | 1 |
| Jones, WB; Lewis, JL; Schneider, J; Shapiro, F | 1 |
| Archimandritis, A; Bacoyiannis, C; Giannopoulos, A; Kalahanis, N; Karatzas, G; Kosmas, C; Kosmidis, P; Papachristodoulou, A; Papadimas, V; Polyzos, A; Sakelaropoulos, N; Tsavaris, N | 1 |
| Blomgren, H; Ragnhammar, P | 1 |
| Ando, M; Fukunari, H; Gonda, T; Hojo, I; Ishida, H | 1 |
| Balat, O; Edwards, CL; Kavanagh, JJ; Kudelka, AP; Silva, E; Verschraegen, CF | 1 |
| Aschele, C; Grossi, F; Guglielmi, A; Sobrero, A; Tixi, L | 1 |
| Ansari, R; Gonin, R; Loehrer, PJ; McClean, J; Miller, KD; Mortimer, J; Pletcher, W; Spiridonidis, CH; Weber, G | 1 |
| Arai, K; Iwasaki, Y; Kitamura, M | 1 |
| Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H | 1 |
| Ahn, T; Hyun, DW; Jung, JT; Kim, DH; Lee, J; Lee, KB; Lee, YH; Sohn, SK; Suh, CS | 1 |
| Fujimori, Y; Iki, K; Imai, H; Iwamoto, S; Kawasaki, S; Kimoto, M; Kubozoe, T; Murakami, T; Mure, T; Onuma, E; Tadaoka, Y; Takeo, T; Tsunoda, T; Yamamoto, Y; Yoshida, K | 1 |
| Gottesman, MM; Pastan, I; Shen, D | 1 |
| Lurain, JR | 1 |
| Sakata, Y; Tsushima, K | 1 |
| Abeloff, MD; Cummings, FJ; Falkson, G; Gelman, RS; Osborne, CK; Pandya, KJ; Sledge, GW; Tormey, D | 1 |
| Beuzeboc, P; Christoforov, B; Debré, B; Dhote, R; Flam, T; Thiounn, N; Zerbib, M | 1 |
| Hato, T; Kaneda, N; Murase, K; Sato, T; Shimokawa, K; Takahashi, C; Takeuchi, T; Tsuya, H | 1 |
| Balme, B; Besançon, C; Devaux, Y; Pincemaille, B; Thomas, L | 1 |
| Kunii, Y; Masamune, R; Takahashi, N | 1 |
| Arai, K; Iwasaki, Y; Kitamura, M; Nakajima, Y | 1 |
| Dono, K; Eguchi, H; Kishimoto, S; Kondo, M; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Nakamura, H; Sakon, M; Shimizu, J; Takeda, Y; Umeshita, K; Wakasa, K | 1 |
| Idezuki, Y; Ishida, H; Nakada, H; Suzuki, T; Tada, M; Takeuchi, I | 1 |
| Buyse, M; Haddad, E; Piedbois, P; Thirion, P; Wolmark, N | 1 |
| Presant, CA; Shani, J; Waluch, V; Weitz, I; Wiseman, CL; Wolf, W | 1 |
| Chan, JY; Chu, AC; Fung, KP | 1 |
| Krege, S; Otto, T; Rübben, H; Suhr, J | 1 |
| Arvelo, F; Bras-Gonçalves, RA; Coquelle, A; De Pinieux, G; Dutrillaux, B; Formento, JL; Lesuffleur, T; Milano, G; Pandrea, I; Pocard, M; Poirson-Bichat, F; Poupon, MF; Ronco, G; Villa, P | 1 |
| Ebinuma, H; Ishii, H; Nakamoto, N; Nakamura, M; Saito, H; Saito, Y; Takagi, T; Wakabayashi, K | 1 |
| Ishikawa, T; Matsui, S; Matsuki, H; Matsuzawa, J; Mita, Y; Sato, S; Tashiro, K; Tashiro, S | 1 |
| Brzozowska, A; Mazurkiewicz, M; Szatkowska, L | 1 |
| Moix, FM; Raufman, JP | 1 |
| Baba, H; Ebuchi, M; Kure, N; Maruyama, M; Nagahama, T; Toukairin, Y | 1 |
| Hojo, T; Ikeda, T; Kawaguchi, M; Kitajima, M; Masamura, S; Matsui, A; Mitsui, Y; Miyabe, R; Takayama, S; Tokura, H | 1 |
| Baba, H; Ebuchi, M; Kure, N; Maruyama, M; Nagahama, T; Tokairin, Y; Yoshida, T | 1 |
| Agata, S; Altavilla, G; De Nicolo, A; Girolami, A; Menin, C; Motta, G; Pietrogrande, F; Vianello, F | 1 |
| Ioka, Z; Nakane, Y; Nakano, K; Osaka, Y; Sako, H; Takemura, N; Tanabe, S; Tsuchiya, K | 1 |
| Day, M; Edwards, AO; Leavey, PJ; Weinberg, A | 1 |
| Blackstock, AW; Case, D; Higgs, V; Melin, SA; Savage, P; Tomlinson, SK; White, DR | 1 |
| Aggarwal, S; Arora, A; Bhalla, S; Murthy, SA; Singh, B; Vohra, R | 1 |
| Chama, CM; Nggada, HA; Nuhu, A | 1 |
| Poirier, LA | 1 |
| Borsos, T; Ohanian, SH; Segerling, M | 3 |
| Cuschieri, A; Swain, C | 1 |
| Kyalwazi, SK; McIntire, KR; Primack, A; Vogel, CL; Waldmann, TA | 1 |
| Morgenthaler, FR; Pettavel, J | 2 |
| Alfonso, A; Bohorquez, J; Gardner, B; Harshaw, D; Hassan, A; Herbsman, H; Newman, J | 1 |
| Oberfield, RA | 3 |
| Rosenberg, SA | 1 |
| Bernard, J; Chelloul, N; Delbrück, H; Schaison, G | 1 |
| Drobník, J; Koutecký, J; Tríska, J; Wichterle, O | 1 |
| Falkson, G | 1 |
| Andreeva, NA; Ershova, IuA; Nemeriuk, MP; Riabokon', NA; Sokolova, AS | 1 |
| Bast, RC; Borsos, T; Greene, SL; Ohanian, SH; Rapp, HJ; Segerling, M; Zbar, B | 1 |
| Scheuer, PJ | 1 |
| Chainuvati, T; Hitanant, S; Nilprabhassorn, P; Umsawasdi, T; Viranuvatti, V | 1 |
| Fernholz, HJ; Frik, W; Nüvemann, M | 1 |
| Jackson, RC; Weber, G | 1 |
| Roth, JJ; Roth, JS | 1 |
| Billings, A; Bitran, JD; Colman, M; DeMeester, TR; Desser, RK; Evans, R; Golomb, HM; Griem, M; Rubenstein, L; Shapiro, C | 1 |
| Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
| Brinkley, DM; Cochrane, AM; Murray-Lyon, IM; Williams, R | 1 |
| Mosijczuk, AD; Ruymann, FB; Sayers, RJ | 1 |
| Habs, G; Habs, M; Schmähl, D | 1 |
| Cady, B; Oberfield, RA; Wellwood, JM | 1 |
| Zimmerman, HJ | 1 |
| Corder, MP; Flannery, EP; Herbst, KD; Justice, GR; Sheets, RF; Stone, WH | 1 |
| Rosenoer, VM; Tornay, AS | 1 |
| Jochimsen, PR; Pearlman, NW; Shirazi, SS; Zike, WL | 1 |
| Boberić, J; Bugarski, M; Dilparić, S; Milosavljević, A; Naumović, P; Tomin, R; Vuletić, L | 1 |
| DeGraw, JI; Dorick, DM; Moccio, DM; Sirotnak, FM | 1 |
| Dubois, JB; Serrou, B | 1 |
| Biran, S; Brufman, G; Hochman, A; Krasnokuki, D | 1 |
| Herman, T; Kim, E | 1 |
| Israel, L | 1 |
| Jugdutt, BI; Turner, FW; Watanabe, M | 1 |
| Bruntsch, U; Gallmeier, WM; Schmidt, CG | 1 |
| Catalano, RB; Creech, RH; Engstrom, PF; Mastrangelo, MJ | 1 |
| Mittal, VK; Saharia, S; Singh, K | 1 |
| Canellos, GP; Chabner, BA; DeVita, VT; Gold, GL; Schein, PS; Young, RC | 2 |
| Desai, DC; Desouza, LJ; Dhir, V; Dinshaw, KA; Jagannath, P; Mohandas, KM; Nagral, A; Sharma, V; Swaroop, VS | 1 |
| Calne, R; Clark, PI; Owen, RA; Stebbings, W; Whelan, JS | 1 |
| Cascinu, S; Catalano, G; Fedeli, A; Luzi Fedeli, S | 1 |
| Arai, K; Kitamura, M; Miyashita, K | 1 |
| Bécouarn, Y; Brunet, R; Bussières, E; Lagarde, P; Ravaud, A | 1 |
| Fujii, Y; Fukuoka, T; Hongo, T; Igarashi, Y; Iijima, S; Matsusita, T; Nakagawa, Y | 1 |
| Caen, J; Cochand-Priollet, B; Lavergne, A; Marteau, P; Mehdi, A; Molho-Sabatier, P; Rambaud, JC | 1 |
| Barbosa, JL; Kamen, BA; Kato, GJ; Weitman, SD | 1 |
| Dai, Y | 1 |
| Bunni, M; Freisheim, JH; Galivan, J; Priest, DG; Rhee, M; Whiteley, JM | 1 |
| Abraham, A; Galivan, J; Gaumont, Y; Kisliuk, RL; Nair, MG | 1 |
| Ajarim, DS; Santhosh-Kumar, CR; Shipkey, FD | 1 |
| Bagshawe, KD; Begent, RH; Bradley, J; Dawson, PM; Kulkarni, RP; Makey, AR; Newlands, ES; Reynolds, KW; Rustin, GJ; Theodorou, NA | 1 |
| Becher, R; Höfeler, H; Kloke, O; May, D; Niederle, N; Richter, R; Scheulen, ME; Schmidt, CG; Wandl, U | 1 |
| Aiba, K; Hirano, A; Horikoshi, N; Inoue, K; Itami, S; Matsumura, T; Matsuoka, A; Mizunuma, N; Mukaiyama, T; Ogawa, M | 1 |
| Dobroskok, LB; Korman, DB; Maslova, IA; Mikaélian, SG; Pines, EV; Snimshchikov, VA | 1 |
| Fukuda, I; Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Kabuto, T; Kameyama, M; Masutani, S; Ohigashi, H; Sasaki, Y | 1 |
| Abad, A; Armengol, M; Barnadas, A; Carles, J; Oller, B; Pastor, MC; Ribas, M; Ribelles, N; Rosell, R; Salva, A | 1 |
| Geller, NL; Penenberg, D; Scher, H; Sternberg, CN; Yagoda, A | 1 |
| Ansari, R; Fisher, WB; Meyer, SC; Roth, BJ; Sledge, GW; Williams, SD | 1 |
| Braga, CA; Mortakis, AE | 1 |
| Ng, TB; Tsao, SW; Yeung, HW | 1 |
| Babich, H; Borenfreund, E; Martin-Alguacil, N | 1 |
| Bahnson, RR; Banner, B; Ernstoff, MS; Miller, RJ; O'Donnell, WF | 1 |
| Najarian, JS; Neglia, JP; Orchard, P; Payne, WD; Pescovitz, MD; Snover, DC | 1 |
| Igawa, M; Ohkuchi, T; Okada, K; Ueda, M; Ueki, T; Usui, T | 1 |
| Akiyama, K; Sumiyoshi, Y; Yano, M | 1 |
| Fried, M; Ilardi, CF; Kalra, J; Sawitsky, A | 1 |
| Barkanov, AI; Komov, DV; Roshchin, EM | 1 |
| Henne-Bruns, D; Kremer, B; Marks, HG; Marks, V; Weh, HJ | 1 |
| Furukawa, H; Hiratsuka, M; Imaoka, S; Ishikawa, O; Iwanaga, T; Kabuto, T; Ohigashi, H; Sasaki, Y; Shibata, T; Yasuda, T | 1 |
| Baba, T; Furukohri, N; Itoh, T; Munakata, A; Ogasawara, H; Saitoh, S; Sakata, Y; Tamura, Y; Tsushima, K; Yoshida, Y | 1 |
| Voigtmann, R | 1 |
| Blaschke, U; Gerber, B; Kasch, R | 1 |
| Eddy, JL; Ihde, DC; Makuch, RW; Matthews, MJ; McIntire, KR; Seeff, LB | 1 |
| Copeland, LJ; Edwards, CL; Gershenson, DM; Gordon, AN; Kavanagh, JJ; Saul, PB | 1 |
| Bander, N; Geller, N; Herr, HW; Morse, MJ; Scher, HI; Sogani, PC; Sternberg, CN; Vaughan, ED; Watson, RC; Yagoda, A | 1 |
| Cagnazzo, P; Cardi, G; Ficorella, C; Frati, L; Marchei, P; Marchetti, P; Ricciuti, FP | 1 |
| Choo, YC; Ma, HK; Wong, LC | 1 |
| Adler, M; Cremer, M; Henry, JP; Lecocq, E; Quiriny, M; Ros, P | 1 |
| Glimelius, B | 1 |
| Aitken, S; Blackstein, M; Dembo, AJ; Gerulath, AH; Osborne, R; Quirt, IC; Rider, WD | 1 |
| Beschorner, J; Cooper, RM; DuBrow, RA; Faintuch, J; Hagle, M; Karl, RC; Levin, B; Shepard, KV; Stablein, D | 1 |
| Lin, G; Liu, KD; Tao, T; Xie, XH; Zhou, J | 1 |
| Aplevich, NN; Gritsaĭ, AA; Kondrat'eva, AP; Lichinitser, MR; Vyshinskaia, GV | 1 |
| Freiha, FS; Hannigan, J; Harker, EG; McWhirter, K; Meyers, FJ; Palmer, JM; Shortliffe, LD; Torti, FM | 1 |
| Iwanaga, T; Koyama, H; Sasaki, Y; Shiba, E; Terasawa, T; Wada, A | 1 |
| Aron-Rosa, D; Auclerc, G; Dhermy, P; Jacquillat, C; Maral, J; Sellami, M; Weil, M | 1 |
| Ellison, NM; Servi, RJ | 1 |
| Ford, J; Margolese, R; Panasci, L | 1 |
| Anko, H; Arai, M; Ide, H; Kitamura, Y; Murata, Y; Ota, S; Suguro, M; Suzuki, S; Yamashita, Y; Yoshii, K | 1 |
| Buffe, D; Burtin, P; Mawas, C; Schweisguth, O | 1 |
| McIntire, KR; Patel, IR; Princler, GL; Vogel, CL | 1 |
| Gallager, HS; Lewis, RP | 1 |
| Morgenthaler, F; Pettavel, J | 2 |
| Chavez, CM; Conn, JH; Fain, WR | 1 |
| Bessot, M; Duprez, A; Kissel, P | 1 |
| Hahn, RG; Moertel, CG; Reitemeier, RJ | 1 |
| Falkson, G; Geddes, EW | 2 |
| Lopes Cardozo, E | 1 |
| Pettavel, J | 1 |
| Rochlin, DB; Smart, CR | 1 |
| Adamson, RH; Henderson, ES; Oliverio, VT | 1 |
| Gorgun, B; Watne, AL | 1 |
| Aust, JB; D'Angio, GJ; Krivit, W; Leonard, AS; Nesbit, ME; Wedemeyer, PP; White, JG | 1 |
| Potter, VR; Sneider, TW | 1 |
| Handschumacher, RE | 1 |
| Crocker, DW; Piro, AJ; Shirley, RL | 1 |
| Bukin, IuV; Raushenbakh, MO; Sergeev, AV | 1 |
| Keeling, JW | 1 |
| Gauldie, J; Hiebert, M; Hillcoat, BL; Marshall, L | 1 |
| Maley, F; Maley, GF | 1 |
| Goldstein, DP | 1 |
| Bowman, RL; Braslow, NM | 1 |
| Adamson, RH; DeVita, VT; Johns, DG; Kyalwazi, SK; Vogel, CL | 1 |
| Borchert, LG; Creasman, WT; Hammond, CB; Parker, RT; Tyrey, L | 1 |
| Bhana, D; Dhru, D; Harrison, NW; Kyalwazi, SK; Primack, A | 1 |
| Sneider, TW | 1 |
| McHenry, CS; Perriard, ER; Santi, DV | 1 |
| Beattie, EJ; Castro, EB; Fortner, JG; Howland, WS; Kim, DK; Kinne, DW; Shiu, MH; Watson, RC | 1 |
| Galt, RM; Knock, FE; Oester, YT; Sylvester, R | 1 |
| Murphy, JF; Wade-Evans, T | 1 |
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| Bengmark, S; Fredlund, P; Hafström, LO; Vang, J | 1 |
| Falkson, G; Geddes, E; Lange, M | 1 |
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| Fortner, JG; Golbey, RB; Mulcare, RJ; Solis, A; Watson, RC | 1 |
| Hughes, J; Stoker, TA | 1 |
| Alford, DA; Allen, LM; Creaven, PJ; Hansen, HH | 1 |
| Akao, T; Fujimoto, S; Ito, B; Miyoshi, T; Nomura, Y | 1 |
| Bersohn, I; Geddes, EW; Purves, LR | 1 |
| Johnston, GS; Jones, AE | 1 |
| Freckman, HA | 1 |
| Broeders, GH; Mastboom, JL; van der Werf, AJ; Vooys, GP | 1 |
| Byron, RL; Keating, JL; Riihimaki, DU; Yonemoto, RH | 1 |
| Ishihara, S | 1 |
| Ediger, AJ; Mason, JH | 1 |
| Carbone, PP; Devita, VT; Serpick, AA | 1 |
| Buckley, K; Gump, FE; Herter, FP; McCarthy, JG; Mulcare, RJ; Ukai, M; Wheeler, B | 1 |
| Sullivan, RD; Zurek, WZ | 1 |
27 review(s) available for methotrexate and Liver Neoplasms
| Article | Year |
|---|---|
SIU-ICUD recommendations on bladder cancer: systemic therapy for metastatic bladder cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Doxorubicin; Gemcitabine; Humans; Liver Neoplasms; Methotrexate; Nivolumab; Paclitaxel; Urinary Bladder Neoplasms; Vinblastine | 2019 |
The role of the MTHFR 677C>T polymorphism in methotrexate-induced liver toxicity: a meta-analysis in patients with cancer.
Topics: Chemical and Drug Induced Liver Injury; Child; Female; Humans; Liver Neoplasms; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2014 |
Clinical aspects of gestational trophoblastic disease: a review based partly on 25-year experience of a statewide registry.
Topics: Brain Neoplasms; Female; Gestational Trophoblastic Disease; Humans; Hydatidiform Mole; Leucovorin; Liver Neoplasms; Methotrexate; Neoplasms, Second Primary; Pregnancy; Queensland; Recurrence; Registries | 2003 |
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy | 2005 |
Post-transplant hepatosplenic T-cell lymphoma successfully treated with HyperCVAD regimen.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Transitional Cell; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunosuppression Therapy; Kidney Transplantation; Liver Neoplasms; Lymphoma, T-Cell; Methotrexate; Middle Aged; Neoplasms, Second Primary; Postoperative Complications; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Splenic Neoplasms; Urinary Bladder Neoplasms; Vesico-Ureteral Reflux; Vincristine | 2008 |
Hepatic intraarterial chemotherapy--current status and future prospects--"If you have a short sword, take a step forward".
Topics: Carcinoma, Hepatocellular; Catheterization; Colonic Neoplasms; Doxorubicin; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Rectal Neoplasms | 1983 |
[A case of retroperitoneal NHL with direct invasion to the liver, pancreas and gastric wall].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Humans; Leucovorin; Liver Neoplasms; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Invasiveness; Pancreatic Neoplasms; Prednisone; Remission Induction; Retroperitoneal Neoplasms; Stomach Neoplasms; Vincristine | 1995 |
Recurrent breast cancer: presentation, diagnosis, and treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Mastectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Radiotherapy; Soft Tissue Neoplasms | 1993 |
Chemotherapy for colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Methotrexate | 1994 |
Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. Advanced Colorectal Cancer Meta-Analysis Project.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Regression Analysis; Survival Analysis | 1994 |
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
How to optimize the effect of 5-fluorouracil modulated therapy in advanced colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Interferons; Leucovorin; Liver Neoplasms; Methotrexate; Phosphonoacetic Acid | 1995 |
Arterial infusion chemotherapy for peritoneal and liver metastasis in gastric cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Recurrence, Local; Peritoneal Neoplasms; Stomach Neoplasms | 1997 |
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Dipyridamole; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Interferons; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nucleotides; Palliative Care; Phosphonoacetic Acid; Randomized Controlled Trials as Topic; Thymidylate Synthase | 1996 |
Management of high-risk gestational trophoblastic disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cyclophosphamide; Dactinomycin; Etoposide; Female; Folic Acid; Humans; Liver Neoplasms; Methotrexate; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms; Vincristine | 1998 |
[Treatment of recurrent gastric cancer].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Doxorubicin; Drug Administration Schedule; Epirubicin; Etoposide; Fluorouracil; Humans; Immunologic Factors; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Mitomycin; Neoplastic Cells, Circulating; Peritoneal Neoplasms; Stomach Neoplasms | 1998 |
[A case of liver metastases of rectal carcinoid successfully treated with hepatic arterial infusion of methotrexate and 5-fluorouracil].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Pelvic Exenteration; Rectal Neoplasms | 1999 |
Survival impact of chemotherapy in patients with colorectal metastases confined to the liver: a re-analysis of 1458 non-operable patients randomised in 22 trials and 4 meta-analyses. Meta-Analysis Group in Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Floxuridine; Fluorouracil; Humans; Injections, Intralesional; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis; Terminally Ill; Treatment Outcome | 1999 |
The role of liver biopsy in the evaluation of liver test abnormalities.
Topics: Biopsy; Cholestasis; Diagnosis, Differential; Fever of Unknown Origin; Hepatitis; Hepatomegaly; Humans; Liver; Liver Diseases; Liver Function Tests; Liver Neoplasms; Methotrexate | 2001 |
Therapeutic approaches to hepatoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Catheterization; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; South Africa | 1975 |
Long-term effects on the liver.
Topics: Anabolic Agents; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Disease; Contraceptives, Oral, Hormonal; Humans; Lipofuscin; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Methotrexate; Oxyphenisatin Acetate; Phenacetin | 1975 |
Drug-induced chronic hepatic disease.
Topics: Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chronic Disease; Fatty Liver; Hemangioendothelioma; Hexestrol; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate; Necrosis; Oxyphenisatin Acetate | 1979 |
[Systemic chemotherapy in metastatic colorectal adenocarcinomas].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Male; Methotrexate; Mitomycin; Nitrosourea Compounds; Pyrimidines; Semustine | 1992 |
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Contraceptive Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Neoplasms; Methotrexate | 1986 |
Systemic cytostatic drug therapy in liver cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1986 |
Riboflavin and cancer: a review.
Topics: Adenine Nucleotides; Animals; Azo Compounds; Benz(a)Anthracenes; Body Weight; Cells, Cultured; Epithelium; Folic Acid Antagonists; Humans; Liver; Liver Neoplasms; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Riboflavin; Riboflavin Deficiency; Transplantation, Homologous | 1973 |
Present experiences with hepatic dearterialization in liver neoplasm.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Catheterization; Dactinomycin; Female; Fluorouracil; Hepatic Artery; Humans; Ligation; Lipids; Liver Circulation; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Remission, Spontaneous | 1974 |
33 trial(s) available for methotrexate and Liver Neoplasms
| Article | Year |
|---|---|
Phase II trial of metronomic chemotherapy as salvage therapy for patients with metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Methotrexate; Middle Aged; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 2008 |
Methotrexate-paclitaxel-epirubicin-carboplatin as second-line chemotherapy in patients with metastatic transitional cell carcinoma of the bladder pretreated with cisplatin-gemcitabine: a phase II study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Epirubicin; Female; Follow-Up Studies; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Paclitaxel; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate; Urinary Bladder Neoplasms | 2013 |
Phase II study of a triplet regimen in advanced colorectal cancer using methotrexate, oxaliplatin and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease-Free Survival; Feasibility Studies; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Treatment Outcome | 2004 |
Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Gene Amplification; Genes, erbB-2; Humans; Immunization, Passive; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Proteins; Neutropenia; Receptor, ErbB-2; Remission Induction; Trastuzumab; Treatment Outcome; Ventricular Dysfunction, Left | 2006 |
Chemotherapy for advanced hepatocellular carcinoma. Adriamycin versus quadruple chemotherapy.
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Vincristine | 1984 |
Newer techniques in cancer chemotherapy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bleomycin; Bone Marrow Transplantation; Carcinoma; Cells, Cultured; Child; Cisplatin; Clinical Trials as Topic; Colonic Neoplasms; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Hepatic Artery; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Mechlorethamine; Melanoma; Meningeal Neoplasms; Methotrexate; Neoplasms; Osteosarcoma; Peritoneal Cavity; Pleura | 1984 |
Randomized trial of cyclophosphamide, doxorubicin, and 5-fluorouracil alone or alternating with a "cycle active" non-cross-resistant combination in women with visceral metastatic breast cancer: a Southeastern Cancer Study Group project.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Nausea; Random Allocation; Thrombocytopenia; Vincristine; Vomiting | 1984 |
Metastatic adenocarcinomas of unknown primary site: a randomized study of two combination-chemotherapy regimens.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Random Allocation | 1980 |
Sequential chemotherapy of advanced colorectal cancer with standard or high-dose methotrexate followed by 5-fluorouracil.
Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Digestive System; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Rectal Neoplasms; Uremia | 1982 |
Reduction of the systemic toxicity of cisplatin by intra-arterial hepatic route administration for liver malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney Diseases; Leucovorin; Liver; Liver Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Ovarian Neoplasms; Remission Induction; Spectrophotometry, Atomic; Tumor Cells, Cultured; Vinblastine | 1995 |
[Intra-arterial 5-FU/intra-venous MTX therapy for metastatic liver lesions].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction | 1995 |
Alternating chemotherapy regimens for patients with metastatic breast cancer. A pilot study based on tumor marker kinetics. Cancer and Leukemia Group B.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Pilot Projects; Remission Induction; Vincristine | 1995 |
Double modulation of 5-fluorouracil in the treatment of advanced colorectal carcinoma: report of a trial with sequential methotrexate, intravenous (loading dose) folinic acid, 5-fluorouracil, and a literature review.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Diarrhea; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
Biochemical modulation of fluorouracil: comparison of methotrexate, folinic acid, and fluorouracil versus folinic acid and fluorouracil in advanced colorectal cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Death; Colorectal Neoplasms; Dose-Response Relationship, Drug; Enzyme Stability; Female; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged | 1996 |
Alternating bolus and continuous infusion 5-fluorouracil: a strategy to overcome resistance to this fluoropyrimidine in advanced colorectal cancer patients.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Palliative Care; Pilot Projects; Remission Induction; Treatment Outcome; Tumor Cells, Cultured | 1996 |
A phase II study of weekly oral methotrexate and zidovudine (AZT) in advanced adenocarcinoma of the pancreas and hepatocellular carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Remission Induction; Zidovudine | 1996 |
Eastern Cooperative Oncology Group randomized trials of observation versus maintenance therapy for patients with metastatic breast cancer in complete remission following induction treatment.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Fluoxymesterone; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prednisone; Remission Induction; Survival Rate; Tamoxifen | 1998 |
Enhancement of fluorouracil uptake in human colorectal and gastric cancers by interferon or by high-dose methotrexate: An in vivo human study using noninvasive (19)F-magnetic resonance spectroscopy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorine Compounds; Fluorouracil; Humans; Infusions, Intravenous; Interferon-alpha; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2000 |
Impact of surgical resection of bladder cancer metastases refractory to systemic therapy on performance score: a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Cystectomy; Doxorubicin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Prospective Studies; Skin Neoplasms; Urinary Bladder Neoplasms; Vinblastine | 2001 |
[Cisplatin and vinorelbine therapy of previously treated advanced breast cancer (preliminary studies)].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Disease Progression; Doxorubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Skin Neoplasms; Treatment Outcome; Vinblastine; Vinorelbine | 2001 |
Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study.
Topics: Abdominal Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Routes; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Survival Rate; Treatment Outcome | 2002 |
Quadruple chemotherapy versus radiotherapy in treatment of primary hepatocellular carcinoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Aspartate Aminotransferases; Bilirubin; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine | 1977 |
[Chemotherapy of metastasizing breast cancers. Indications and results].
Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Thoracic Neoplasms; Time Factors; Vincristine | 1975 |
Combination chemotherapy and radiation for palliation of hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Prospective Studies; Remission Induction; Survival Analysis | 1992 |
[Comparative evaluation of 2 schedules of administration of anti- neoplastic drugs by the CMF protocol in disseminated breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Prospective Studies; Remission Induction | 1991 |
Sequential combination of methotrexate (MTX), 5-fluorouracil (FU), and high-dose folinic acid (FA) in advanced colorectal cancer: double biochemical modulation?
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Survival Rate | 1991 |
Methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic breast cancer. A phase II trial of the Hoosier Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Evaluation; Female; Hematologic Diseases; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
A randomized trial in postmenopausal patients with advanced breast cancer comparing endocrine and cytotoxic therapy given sequentially or in combination. The Australian and New Zealand Breast Cancer Trials Group, Clinical Oncological Society of Australia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Menopause; Methotrexate; Middle Aged; Prognosis; Random Allocation; Receptors, Estrogen; Tamoxifen; Vincristine | 1986 |
Systemic cytostatic drug therapy in liver cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Colonic Neoplasms; Doxorubicin; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Rectal Neoplasms; Semustine; Vincristine | 1986 |
The fate of the bladder in patients with metastatic bladder cancer treated with cisplatin, methotrexate and vinblastine: a Northern California Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pelvic Neoplasms; Urinary Bladder Neoplasms; Vinblastine | 1985 |
Infusion of liver tumours.
Topics: Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Humans; Liver Neoplasms; Methotrexate | 1968 |
Intra-arterial chemotherapy in the treatment of primary liver cancer.
Topics: Arteries; Clinical Trials as Topic; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms; Male; Methotrexate; Placebos | 1974 |
Serum alpha-feto-protein and primary cancer of the liver in man.
Topics: Adult; Black People; Blood Proteins; Cyclophosphamide; Fetus; Humans; Immunoassay; Immunodiffusion; Infant, Newborn; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Placebos; South Africa; White People | 1970 |
275 other study(ies) available for methotrexate and Liver Neoplasms
| Article | Year |
|---|---|
Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.
Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry; Fibroblasts; Folic Acid; Folic Acid Antagonists; Humans; Lacticaseibacillus casei; Liver Neoplasms; Lymphoma; Molecular Structure; Streptococcus; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium | 2003 |
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Topics: Animals; Cell Count; Drug Resistance, Neoplasm; E2F4 Transcription Factor; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Lysosomes; Male; Metformin; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Organoids; Proteolysis; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Transcription, Genetic | 2021 |
Pneumonia and Meningoencephalitis Due to Varicella-zoster Virus Reinfection and Epstein-Barr Virus Reactivation in a Patient with Rheumatoid Arthritis.
Topics: Aged; Arthritis, Rheumatoid; Epstein-Barr Virus Infections; Female; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Liver Neoplasms; Lymphoproliferative Disorders; Meningoencephalitis; Methotrexate; Pneumonia; Reinfection; Valacyclovir | 2022 |
Identification of copper metabolism and cuproptosis-related subtypes for predicting prognosis tumor microenvironment and drug candidates in hepatocellular carcinoma.
Topics: Apoptosis; Carcinoma, Hepatocellular; Copper; CTLA-4 Antigen; DNA Copy Number Variations; Humans; Imatinib Mesylate; Liver Neoplasms; Methotrexate; Prognosis; Sorafenib; Tumor Microenvironment | 2022 |
Mn-SOD alleviates methotrexate-related hepatocellular injury via GSK-3β affecting anti-oxidative stress of HO-1 and Drp1.
Topics: Carcinoma, Hepatocellular; Dynamins; Glycogen Synthase Kinase 3 beta; Humans; Liver Neoplasms; Methotrexate; MicroRNAs; Oxidative Stress; Superoxide Dismutase; Superoxides | 2022 |
A case of hepatosplenic T-cell lymphoma successfully treated by HLA haploidentical stem cell transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Immunosuppressive Agents; Liver Neoplasms; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Prednisolone; Splenic Neoplasms; Tacrolimus; Transplantation, Haploidentical; Treatment Outcome; Vincristine | 2020 |
Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Carcinoma, Hepatocellular; Cell Proliferation; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Flavanones; Hep G2 Cells; Humans; Inflammation Mediators; Liver; Liver Neoplasms; Male; Methotrexate; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats | 2020 |
Methotrexate-associated Lymphoproliferative Disorder in the Liver Resembling Hepatocellular Carcinoma Treated with Transarterial Chemoembolization.
Topics: Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Diagnosis, Differential; Female; Humans; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoproliferative Disorders; Methotrexate | 2020 |
[A CASE OF METASTATIC BLADDER UROTHELIAL CARCINOMA WHOSE DISEASE WAS CONTROLLED FOR A RELATIVE LONG PERIOD BY MULTIDISCIPLINARY TREATMENT INCLUDING RADIATION TO A LUNG METASTASIS AND MULTIPLE COURSES OF CHEMOTHERAPY].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carcinoma; Chemoradiotherapy; Cisplatin; Combined Modality Therapy; Doxorubicin; Fatal Outcome; Female; Humans; Infusions, Intra-Arterial; Kidney Neoplasms; Kidney Pelvis; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Invasiveness; Organ Sparing Treatments; Time Factors; Ureteral Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms; Vinblastine | 2017 |
Oxidative phosphorylation activation is an important characteristic of DOX resistance in hepatocellular carcinoma cells.
Topics: Adenosine Triphosphate; ATP Synthetase Complexes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Deoxyglucose; Doxorubicin; Drug Resistance, Neoplasm; Energy Metabolism; Glycolysis; Humans; Ketone Oxidoreductases; Liver Neoplasms; Malates; Methotrexate; Oxidative Phosphorylation | 2018 |
Accelerated Progression of Hepatocellular Carcinoma during Immunosuppressive Therapy with Abatacept for Rheumatoid Arthritis.
Topics: Abatacept; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Hepatocellular; Disease Progression; Female; Humans; Immunosuppressive Agents; Liver Neoplasms; Methotrexate | 2019 |
Squamous Cell Lung Cancer: Methotrexate Withdrawal Induced Spontaneous Regression of Liver Metastases.
Topics: Carcinoma, Squamous Cell; Epithelial Cells; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate | 2020 |
Methotrexate-Associated Lymphoproliferative Disorder: A Rare Case of Large Liver Tumors.
Topics: Aged; Antirheumatic Agents; Female; Humans; Liver Neoplasms; Lymphoproliferative Disorders; Methotrexate; Tumor Burden | 2019 |
Methotrexate-associated primary hepatic lymphoma and cranial neuropathy in a patient with rheumatoid arthritis: A case report with clinical follow-up over a 7-year period.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cranial Nerve Diseases; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lymphoma; Methotrexate; Recurrence | 2019 |
Radixin knockdown improves the accumulation and efficiency of methotrexate in tumor cells.
Topics: A549 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Membrane; Cell Proliferation; Cell Survival; Cytoskeletal Proteins; Gene Knockdown Techniques; Hep G2 Cells; Humans; Liver Neoplasms; Male; Membrane Proteins; Methotrexate; Mice; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2019 |
Topics: Adalimumab; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Immunosuppressive Agents; Liver; Liver Neoplasms; Male; Methotrexate; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection | 2019 |
Inherent and acquired resistance to paclitaxel in hepatocellular carcinoma: molecular events involved.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Caveolin 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Fatty Acid Synthases; Humans; Liver Neoplasms; Methotrexate; Paclitaxel; Vinblastine | 2013 |
pH-sensitive pullulan-based nanoparticle carrier of methotrexate and combretastatin A4 for the combination therapy against hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Delayed-Action Preparations; Glucans; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Nanoparticles; Stilbenes | 2013 |
Thoracoscopic hepatectomy for malignant liver tumor.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxorubicin; Hepatectomy; Humans; Japan; Liver Neoplasms; Male; Methotrexate; Operative Time; Thoracoscopy; Vincristine | 2014 |
[A case of intraventricular dissemination arising from hepatocelullar carcinoma effectively treated with intrathecal administration of methotrexate].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cerebral Ventricle Neoplasms; Humans; Injections, Spinal; Liver Neoplasms; Male; Methotrexate | 2014 |
Vitamin C enhances anticancer activity in methotrexate‑treated Hep3B hepatocellular carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Liver Neoplasms; Methotrexate; Oxygen | 2014 |
Core-shell nanoparticles based on pullulan and poly(β-amino) ester for hepatoma-targeted codelivery of gene and chemotherapy agent.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Carriers; Glucans; Green Fluorescent Proteins; Hep G2 Cells; Humans; Liver Neoplasms; Methotrexate; Mice; Mice, Nude; Nanoparticles; Particle Size; Polymers; Transfection; Xenograft Model Antitumor Assays | 2014 |
Gestational trophoblastic neoplasia: treatment outcomes from a single institutional experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Choriocarcinoma; Cisplatin; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Hysterectomy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Remission Induction; Retrospective Studies; Risk Factors; Salvage Therapy; Survival Rate; Uterine Neoplasms; Vaginal Neoplasms; Vincristine; Young Adult | 2015 |
Methotrexate-related primary hepatic lymphoma in a patient with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Neoplasms; Lymphoma, B-Cell; Methotrexate; Middle Aged; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
The comparison of oncologic outcomes between metastatic upper tract urothelial carcinoma and urothelial carcinoma of the bladder after cisplatin-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Deoxycytidine; Doxorubicin; Female; Follow-Up Studies; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Urologic Neoplasms; Vinblastine | 2015 |
A case of multiple hepatic lesions associated with methotrexate-associated lymphoproliferative disorder.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Follow-Up Studies; Humans; Liver; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Renal Insufficiency, Chronic | 2016 |
Spatial controlled multistage nanocarriers through hybridization of dendrimers and gelatin nanoparticles for deep penetration and therapy into tumor tissue.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dendrimers; Drug Delivery Systems; Drug Liberation; Gelatin; Humans; Liver Neoplasms; Male; Matrix Metalloproteinase 2; Methotrexate; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Spheroids, Cellular | 2017 |
A case of primary hepatic Burkitt's lymphoma.
Topics: Antimetabolites, Antineoplastic; Burkitt Lymphoma; Combined Modality Therapy; Cytarabine; Diagnosis, Differential; Humans; Liver Neoplasms; Male; Methotrexate; Tomography, X-Ray Computed; Young Adult | 2008 |
Long-term survival after combined modality treatment in metastatic bladder cancer patients presenting with supra-regional tumor positive lymph nodes only.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Cystectomy; Disease-Free Survival; Doxorubicin; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Remission Induction; Survival Rate; Urinary Bladder Neoplasms; Vinblastine | 2009 |
Gestational trophoblastic tumor with liver metastasis after misoprostol abortion.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Liver Neoplasms; Methotrexate; Misoprostol; Pregnancy; Uterine Neoplasms; Vincristine | 2009 |
Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Brain Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Feeding Behavior; Hippocampus; Immunohistochemistry; Liver Neoplasms; Male; Methotrexate; Neoplasm Transplantation; Pica; Rats; Rats, Inbred BUF | 2010 |
Gallbladder squamous cell carcinoma in the setting of low-dose methotrexate use.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cholecystectomy, Laparoscopic; Cisplatin; Dermatologic Agents; Dose-Response Relationship, Drug; Fatal Outcome; Female; Fluorouracil; Gallbladder Neoplasms; Gallstones; Humans; Incidental Findings; Liver Neoplasms; Methotrexate; Neoplasm Seeding; Peritoneal Neoplasms; Psoriasis | 2009 |
[Choriocarcinoma with pulmonary metastasis: diagnosis and treatment].
Topics: Antimetabolites, Antineoplastic; Biopsy; Choriocarcinoma; Choriocarcinoma, Non-gestational; Chorionic Gonadotropin; Diagnosis, Differential; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Pancreatic Neoplasms; Prognosis; Radiography, Thoracic; Remission Induction; Scalp; Skin; Skin Neoplasms; Tomography, X-Ray Computed | 2009 |
[Therapeutic effects of vinorelbine-based chemotherapy--retrospective study of 65 patients with metastatic or relapsed breast cancer].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Retrospective Studies; Trastuzumab; Vinblastine; Vinorelbine | 2010 |
[A case of recurrent breast cancer with life-threatening liver metastasis remarkably responding to classical CMF].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate | 2010 |
[A case of multidrug-resistant breast cancer associated with multiple hepatic and bone metastases for which cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy proved effective].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged | 2010 |
Comparison of the multi-drug resistant human hepatocellular carcinoma cell line Bel-7402/ADM model established by three methods.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Glutathione; Glutathione Transferase; Humans; Inhibitory Concentration 50; Liver Neoplasms; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Time Factors; Xenograft Model Antitumor Assays | 2010 |
Salvage chemotherapy with methotrexate, etoposide and actinomycin D in men with metastatic nonseminomatous germ cell tumors with a choriocarcinoma component: a preliminary report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Choroid Neoplasms; Dactinomycin; Etoposide; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasms, Germ Cell and Embryonal; Salvage Therapy; Testicular Neoplasms; Treatment Outcome | 2010 |
Intrathecal administration of trastuzumab with cytarabine and methotrexate in breast cancer patients with leptomeningeal carcinomatosis.
Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Injections, Spinal; Liver Neoplasms; Meningeal Carcinomatosis; Methotrexate; Neoplasm Metastasis; Receptor, ErbB-2; Trastuzumab; Treatment Outcome | 2011 |
Etoposide, cisplatin-etoposide, methotrexate, actinomycin-D as primary treatment for management of very-high-risk gestational trophoblastic neoplasia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dactinomycin; Disease Progression; Etoposide; Female; Gestational Trophoblastic Disease; Humans; India; Liver Neoplasms; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Risk; Salvage Therapy; Survival Rate; Treatment Outcome; Young Adult | 2011 |
Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis.
Topics: Active Transport, Cell Nucleus; Antimetabolites, Antineoplastic; beta Catenin; Cadherins; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fluorouracil; Gene Knockdown Techniques; HCT116 Cells; HT29 Cells; Humans; Liver Neoplasms; Methotrexate; Neoplasm Invasiveness; Transcription, Genetic | 2012 |
Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.
Topics: Analysis of Variance; Antibodies, Monoclonal; Azathioprine; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatoblastoma; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Infliximab; Liver Neoplasms; Mercaptopurine; Methotrexate; Sensitivity and Specificity; Thioguanine | 2012 |
[Anti-rheumatic drugs].
Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate | 2012 |
Delivery of chemotherapeutic drugs in tumour cell-derived microparticles.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Cell-Derived Microparticles; Cisplatin; Drug Carriers; Female; Liver Neoplasms; Methotrexate; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasms; Neoplasms, Experimental; Ovarian Neoplasms | 2012 |
Interaction between Gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Death; Drug Resistance, Neoplasm; Drug Synergism; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Melanoma, Experimental; Methotrexate; Mice; Pancreatic Neoplasms; Rats; Tetrahydrofolate Dehydrogenase; Xanthones | 2013 |
Best of the AASLD. Highlights from the 52nd Annual Meeting of the American Association for the Study of Liver Diseases. November 9-13, 2001, Dallas, TX.
Topics: Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Disease Progression; Hepatitis; Hepatitis, Viral, Human; Humans; Hypertension, Portal; Liver; Liver Cirrhosis, Biliary; Liver Diseases; Liver Neoplasms; Liver Transplantation; Methotrexate | 2002 |
[A case of gastric cancer associated with synchronous liver metastasis successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2002 |
[The binding characteristics of insulin-MTX to insulin receptor].
Topics: Antimetabolites, Antineoplastic; Binding Sites; Carcinoma, Hepatocellular; Cell Membrane; Cell Separation; Drug Carriers; Humans; Insulin; Liver Neoplasms; Methotrexate; Receptor, Insulin | 2001 |
S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Forecasting; Humans; Japan; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Pyridines; Severity of Illness Index; Stomach Neoplasms; Survival Analysis; Tegafur; Time Factors; Treatment Outcome | 2003 |
[A case of advanced gastric cancer with liver and intra-abdominal lymph node metastasis treated by hypertensive selective chemotherapy with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Pancreatic Neoplasms; Stomach Neoplasms; Tegafur | 2003 |
Metabolism of C136-dichloromethotrexate by transplantable liver tumors.
Topics: Carcinoma, Hepatocellular; Folic Acid Antagonists; Liver; Liver Neoplasms; Methotrexate | 1962 |
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Erythrocyte Count; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Sulfobromophthalein; Transaminases; Uterine Cervical Neoplasms | 1964 |
HEPATIC CHEMOTHERAPY BY ARTERIAL AND VENOUS INFUSION.
Topics: Catheterization; Clinical Enzyme Tests; Dogs; Fluorouracil; Hepatic Artery; Hepatic Veins; Infusions, Parenteral; Leucovorin; Liver Function Tests; Liver Neoplasms; Methotrexate; Research; Toxicology; Veins | 1964 |
CANCER CHEMOTHERAPY BY PROLONGED ARTERIAL INFUSION.
Topics: Angiography; Arm; Brachiocephalic Trunk; Brain Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorescent Dyes; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Iliac Artery; Leg; Liver Neoplasms; Methotrexate; Neoplasms; Pelvic Neoplasms; Subclavian Artery; Temporal Arteries; Thoracic Neoplasms; Toxicology | 1964 |
CLINICAL MANAGEMENT OF SOFT PART SARCOMAS.
Topics: Chlorambucil; Dactinomycin; Geriatrics; Humans; Leiomyosarcoma; Liposarcoma; Liver Neoplasms; Methotrexate; Neoplasms; Palliative Care; Pathology; Pelvic Neoplasms; Radiography, Thoracic; Rhabdomyosarcoma; Sarcoma; Surgical Procedures, Operative; Thigh | 1964 |
PRIMARY CARCINOMA ARISING IN NORMAL LIVER IN A BOY AGED 7.
Topics: Carcinoma; Carcinoma, Hepatocellular; Child; Diagnosis, Differential; Hepatectomy; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasms; Pathology; Teratoma | 1964 |
REGRESSION OF METASTATIC HEPATOMEGALY FROM MAMMARY CARCINOMA. CYTOTOXIC COMBINATION CHEMOTHERAPY WITH 5-FU.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hepatomegaly; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Neoplasms; Prednisone; Testosterone; Thiotepa; Toxicology; Vitamin B 12 | 1964 |
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastrointestinal Diseases; Hodgkin Disease; Leukemia; Leukemia, Myeloid; Liver Neoplasms; Lymphoma; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Pathology; Radiation Injuries; Stomach; Toxicology; Vinblastine; Vincristine; Wilms Tumor | 1965 |
HEPATIC TUMOURS IN CHILDHOOD AND THEIR TREATMENT BY MAJOR HEPATIC RESECTION.
Topics: Carcinoma; Carcinoma, Hepatocellular; Child; Hamartoma; Hepatectomy; Humans; Infant; Liver Neoplasms; Methotrexate; Mortality; Neoplasms; Pathology; Postoperative Complications; Prognosis | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. II. THYMIDINE UPTAKE IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; DNA; DNA, Neoplasm; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Neoplasms, Experimental; Pharmacology; Pyrimidines; Radiometry; Rats; Research; Thymidine; Tritium | 1965 |
A RADIOENZYMATIC ASSAY FOR FOLIC ACID ANTAGONISTS IN BIOLOGICAL FLUIDS.
Topics: Biological Assay; Blood; Carcinoma, Hepatocellular; Cerebrospinal Fluid; Chromatography; Folic Acid Antagonists; Humans; Leukemia; Liver Neoplasms; Methotrexate; Oxidoreductases; Research; Urine | 1965 |
[A report of two cases--two patients of the extremely advanced hepatocellular carcinoma have responded completely for a long time after a combination therapy consisting of arterial chemotherapy and injection of interferon-alpha].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Fluorouracil; Hepatitis C; Humans; Infusions, Intra-Arterial; Injections, Subcutaneous; Interferon-alpha; Liver Neoplasms; Male; Methotrexate; Prognosis; Remission Induction | 2003 |
[Multiple metastases of the penile cancer: an experience of combination chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplastic Cells, Circulating; Penile Neoplasms; Penis | 2004 |
[Active chemotherapy with gemcitabine, carboplatin and docetaxel for three patients with MVAC-resistant liver metastasis of urothelial carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Docetaxel; Doxorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Gemcitabine; Humans; Kidney Neoplasms; Liver Neoplasms; Male; Methotrexate; Middle Aged; Taxoids; Urinary Bladder Neoplasms; Vinblastine | 2004 |
[A case of curatively resected gastric cancer through an effective response to chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Jejunostomy; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoadjuvant Therapy; Neoplasm Invasiveness; Pancreatic Neoplasms; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms | 2004 |
Receptor binding characteristics and cytotoxicity of insulin-methotrexate.
Topics: Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Chromatography, Gel; Chromatography, High Pressure Liquid; Drug Carriers; Hepatocytes; Humans; Insulin; Liver Neoplasms; Methotrexate; Receptor, Insulin | 2004 |
Prolonged perturbation of the oscillations of hepatoma Fao cell proliferation by a single small dose of methotrexate.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Folic Acid Antagonists; Liver Neoplasms; Methotrexate; Nonlinear Dynamics; Oscillometry; Rats | 2005 |
The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells.
Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Line, Tumor; Folic Acid; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Membrane Transport Proteins; Methotrexate; Reduced Folate Carrier Protein; RNA, Small Interfering; Transfection | 2005 |
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combinations; Floxuridine; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Neoplasm Staging; Picibanil; Proteoglycans; Stomach Neoplasms; Tegafur; Uracil | 2005 |
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.
Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunologic Factors; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Remission Induction; Uridine; Vitamin B Complex | 2006 |
Epstein-Barr virus infection associated hepatic lymphoma in a patient treated with methotrexate for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Disease-Free Survival; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Liver Neoplasms; Lymphoma, B-Cell; Methotrexate; Middle Aged; Withholding Treatment | 2006 |
Remission of hepatic metastasis from colon cancer after methotrexate withdrawal.
Topics: Adenocarcinoma, Mucinous; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Colectomy; Colonic Neoplasms; Humans; Liver Neoplasms; Lymphocyte Activation; Male; Methotrexate; T-Lymphocytes, Cytotoxic; Tomography, X-Ray Computed | 2006 |
Metastatic choriocarcinoma successfully treated with paclitaxel and carboplatin after interstitial lung disease induced by EMA-CO.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Liver Neoplasms; Lung Diseases, Interstitial; Lung Neoplasms; Methotrexate; Paclitaxel; Uterine Neoplasms; Vincristine | 2006 |
[Establishment of a multidrug-resistant cell line BEL-7402/5-FU of human hepatocellular carcinoma and its biological characteristics].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Vincristine | 2006 |
Treatment and prognosis of post term choriocarcinoma in The Netherlands.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cohort Studies; Cyclophosphamide; Dactinomycin; Etoposide; Female; Humans; Hydatidiform Mole; Liver Neoplasms; Lung Neoplasms; Methotrexate; Netherlands; Pregnancy; Prognosis; Retrospective Studies; Uterine Neoplasms; Vincristine | 2006 |
[An abdominal Burkitt's lymphoma in acute phase. Case report].
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Burkitt Lymphoma; Cytarabine; Diagnosis, Differential; Humans; Ileal Neoplasms; Immunohistochemistry; Liver Neoplasms; Male; Methotrexate; Radiography, Abdominal; Remission Induction; Tomography, X-Ray Computed; Ultrasonography | 2006 |
Local recurrence and distant metastasis of supratentorial primitive neuro-ectodermal tumor in an adult patient successfully treated with intensive induction chemotherapy and maintenance temozolomide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Prednisone; Remission Induction; Supratentorial Neoplasms; Temozolomide; Treatment Outcome; Vincristine | 2007 |
A patient with breast cancer with hepatic metastases and a complete response to herceptin as monotherapy.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Karnofsky Performance Status; Liver Neoplasms; Lymphatic Metastasis; Mastectomy, Modified Radical; Methotrexate; Radiotherapy Dosage; Receptor, ErbB-2; Tamoxifen; Time Factors; Tomography, X-Ray Computed; Trastuzumab; Treatment Outcome | 2006 |
Downregulation of xIAP expression by small interfering RNA inhibits cellular viability and increases chemosensitivity to methotrexate in human hepatoma cell line HepG2.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Genetic Vectors; Humans; Liver Neoplasms; Methotrexate; Molecular Sequence Data; RNA, Small Interfering; Sequence Homology, Nucleic Acid; Substrate Specificity; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Cell Survival; Cisplatin; Down-Regulation; Doxorubicin; Etoposide; Female; HeLa Cells; Humans; Inhibitor of Differentiation Protein 1; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Mitomycin; Nasopharyngeal Neoplasms; Paclitaxel; Prostatic Neoplasms; Vincristine | 2007 |
Male breast cancer with mandibular metastasis. A case report.
Topics: Aged; Androstadienes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Cortisone; Cyclophosphamide; Diphosphonates; Docetaxel; Fatal Outcome; Fluorouracil; Furosemide; Humans; Imidazoles; Liver Neoplasms; Male; Mandibular Neoplasms; Mastectomy, Modified Radical; Methotrexate; Omeprazole; Osteolysis; Phenobarbital; Taxoids; Toremifene; Vinblastine; Vinorelbine; Zoledronic Acid | 2007 |
[Diagnosis and prognosis study of breast carcinoma with micropapillary component].
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Tamoxifen | 2007 |
Diffuse large B-cell lymphoma in a patient with rheumatoid arthritis treated with infliximab and methotrexate.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Incompatibility; Female; Humans; Infliximab; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Middle Aged; Skin Neoplasms; Thoracic Wall; Treatment Outcome | 2008 |
Treatment of inoperable cancer of the liver by intra-arterial radioactive isotopes and chemotherapy.
Topics: Chemotherapy, Cancer, Regional Perfusion; Gold Isotopes; Humans; Iodine Radioisotopes; Liver Neoplasms; Methotrexate; Radionuclide Imaging; Rose Bengal; Yttrium Isotopes | 1967 |
Severe incompatible transfusion reaction without demonstrable antibodies.
Topics: Antibodies; Autoantibodies; Blood Group Incompatibility; Humans; Hydrocortisone; Isoantibodies; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Metastasis; Thymus Neoplasms | 1967 |
Further experience in treating patients with hepatocellular carcinoma in Uganda.
Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Azacitidine; Carcinoma, Hepatocellular; Child; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Hepatic Artery; Humans; Injections, Intravenous; Ligation; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pigmentation Disorders; Razoxane; Uganda | 1980 |
[Generalized metastasizing chorion carcinoma with complete remission after cytostatic therapy].
Topics: Adult; Breast Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyclophosphamide; Dactinomycin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Pregnancy; Uterine Neoplasms; Vaginal Neoplasms | 1983 |
Model for specific rescue of normal hepatocytes during methotrexate treatment of hepatic malignancy.
Topics: alpha-Fetoproteins; Asialoglycoprotein Receptor; Asialoglycoproteins; Carcinoma, Hepatocellular; Cells, Cultured; Fetuins; Glycoproteins; Humans; Leucovorin; Liver; Liver Neoplasms; Methotrexate; Receptors, Cell Surface | 1983 |
Membrane characteristics of primary hepatocyte cultures and a stable hepatocarcinoma cell line.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Liver; Liver Neoplasms; Male; Methotrexate; Microtubules; Orosomucoid; Rats; Receptors, Cell Surface; Tetrahydrofolates | 1980 |
Chemotherapy of vinyl chloride-associated hepatic angiosarcoma.
Topics: Adult; Carcinoma, Hepatocellular; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Hemangiosarcoma; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Occupational Diseases; Vinyl Chloride; Vinyl Compounds | 1981 |
Prognostic implications of stage of disease and sites of metastases in patients with small cell carcinoma of the lung treated with intensive combination chemotherapy.
Topics: Aged; Bone Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Diseases; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Soft Tissue Neoplasms | 1981 |
Fulminant lung metastases from cancer of the breast.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorouracil; Humans; Immune Tolerance; Immunity, Cellular; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Respiratory Insufficiency; Vincristine | 1981 |
Evaluation of weekly escalating doses of dichloromethotrexate in patients with hepatocellular carcinoma and other solid tumors.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Administration Schedule; Female; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Protein Binding; Serum Albumin | 1982 |
Mechanisms of immunological eradication of a syngeneic guinea pig tumor. II. Effect of methotrexate treatment and T cell depletion of the recipient on adoptive immunity.
Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Guinea Pigs; Hypersensitivity, Delayed; Immunization, Passive; Liver Neoplasms; Lymphocyte Activation; Lymphocyte Depletion; Male; Methotrexate; Spleen; T-Lymphocytes | 1983 |
Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Eruptions; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Rectal Neoplasms | 1984 |
Sequential methotrexate and 5-FU in CMFP (cyclophosphamide, methotrexate, 5-FU, and prednisone) therapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Recurrence | 1984 |
The treatment of malignant histiocytosis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Leucovorin; Liver Neoplasms; Lymphatic Diseases; Male; Methotrexate; Middle Aged; Platelet Count; Prednisone; Prognosis; Splenectomy; Splenic Neoplasms; Vincristine | 1984 |
Kinetics of methotrexate, dacarbazine and 5-fluorouracil during isolated liver perfusion.
Topics: Animals; Biotransformation; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Kinetics; Liver Neoplasms; Methotrexate | 1983 |
First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary.
Topics: Animals; Antineoplastic Agents; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Dacarbazine; Dogs; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Rectal Neoplasms | 1983 |
Ultrastructural changes in the dog liver cell after isolated liver perfusion with various cytotoxins.
Topics: Animals; Antineoplastic Agents; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; Dacarbazine; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Liver; Liver Neoplasms; Methotrexate; Microscopy, Electron | 1983 |
Irradiation of liver metastases due to gestational choriocarcinoma.
Topics: Adult; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Humans; Liver Neoplasms; Methotrexate; Pregnancy | 1983 |
Chemotherapy of a malignant, metastasizing giant-cell tumor of bone: report of an unusual case and the response to combination chemotherapy.
Topics: Adolescent; Antineoplastic Agents; Bone Neoplasms; Drug Therapy, Combination; Female; Giant Cell Tumors; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Talus; Tibia; Vincristine | 1982 |
Skin metastases from malignant gestational trophoblastic disease: report of two cases.
Topics: Adult; Buttocks; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Methotrexate; Pregnancy; Skin Neoplasms; Uterine Neoplasms | 1982 |
Therapy of liver tumors metastatic from colorectal cancer with whole-liver radiation combined with 5-FU, adriamycin, and methotrexate.
Topics: Aged; Colonic Neoplasms; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Rectal Neoplasms | 1982 |
Treatment of asymptomatic metastatic cancer to the liver from primary colon and rectal cancer by the intraarterial administration of chemotherapy and radioactive isotopes.
Topics: Antineoplastic Agents; Catheters, Indwelling; Cisplatin; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate; Prognosis; Rectal Neoplasms; Yttrium Radioisotopes | 1982 |
Rectal adenocarcinoma with germ cell elements treated with chemotherapy.
Topics: Adenocarcinoma; Adult; alpha-Fetoproteins; Choriocarcinoma; Chorionic Gonadotropin; Endodermal Sinus Tumor; Fatal Outcome; Female; Humans; Liver Neoplasms; Methotrexate; Neoplasms, Multiple Primary; Rectal Neoplasms | 1993 |
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Topics: Carcinoma, Hepatocellular; Cell Line; Colforsin; Dexamethasone; Gene Expression Regulation, Neoplastic; Glycoprotein Hormones, alpha Subunit; Humans; Hydroxyurea; Kinetics; Liver Neoplasms; Methotrexate; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Clostridium septicum abscess in hepatic metastases: successful medical management.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Carmustine; Ceftazidime; Cisplatin; Clindamycin; Clostridium Infections; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Gases; Granulocyte Colony-Stimulating Factor; Humans; Imipenem; Immunocompromised Host; Liver Abscess; Liver Neoplasms; Methotrexate; Neutropenia; Sepsis | 1994 |
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; KB Cells; Liver Neoplasms; Methotrexate; Mice; Mice, Inbred BALB C; Mitomycin; Spiro Compounds; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uridine | 1995 |
Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Carcinoma, Hepatocellular; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Female; Folate Receptors, GPI-Anchored; Genetic Complementation Test; Humans; Kinetics; Liver Neoplasms; Methotrexate; Mice; Molecular Sequence Data; Mutagenesis; Phenotype; Plasmids; Receptors, Cell Surface; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured | 1995 |
[A case report: multiple liver metastasis from gastric cancer responding to intraarterial infusion of sequential low-dose MTX and 5-FU].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Stomach Neoplasms | 1994 |
Abdominal sonogram may prevent complications from liver biopsy.
Topics: Abdomen; Aged; Biopsy, Needle; Hemangioma; Humans; Liver; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Skin Neoplasms; Ultrasonography | 1994 |
High-dose, brief duration, multiagent chemotherapy for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hemorrhage; Humans; Leucovorin; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Survival Rate; Thrombocytopenia | 1994 |
[Intraarterial infusion chemotherapy for recurrent or unresectable gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Mitomycin; Peritonitis; Prognosis; Stomach Neoplasms; Survival Rate | 1993 |
Liver metastases of gestational trophoblastic tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Dactinomycin; Etoposide; Female; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Pregnancy; Retrospective Studies; Treatment Outcome; Trophoblastic Neoplasms; Uterine Neoplasms | 1993 |
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Remission Induction; Tegafur; Uracil | 1993 |
[A case report: multiple liver metastasis of gastric cancer responding to intraarterial infusion of MTX and 5-FU].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms | 1993 |
Treatment of resistant gestational choriocarcinoma with taxol: a report of two cases.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Female; Frontal Lobe; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Paclitaxel; Platinum; Pregnancy; Pregnancy Complications, Neoplastic; Uterine Neoplasms; Vincristine | 1996 |
[A case of Borrmann type 4 gastric cancer successfully treated with MTX and 5-FU therapy through the hepatic artery].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Stomach Neoplasms | 1996 |
Unusual presentation of a metastatic choriocarcinoma following a full term pregnancy: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Choriocarcinoma; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Dactinomycin; Etoposide; Fatal Outcome; Female; Humans; Liver Neoplasms; Methotrexate; Pregnancy; Uterine Neoplasms; Vincristine | 1996 |
Hepatosplenic T-cell lymphoma: prolymphocytic transformation 18 months after splenectomy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Combined Modality Therapy; Doxorubicin; Female; Hepatomegaly; Humans; Liver Neoplasms; Lymphoma, T-Cell, Peripheral; Methotrexate; Prednisolone; Remission Induction; Splenectomy; Splenic Neoplasms; Splenomegaly; Vincristine | 1997 |
[A case of papillary adenocarcinoma of the stomach with liver metastases and carcinomatous peritonitis treated effectively by methotrexate/5-fluorouracil sequential chemotherapy].
Topics: Adenocarcinoma, Papillary; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Schedule; Fluorouracil; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peritonitis; Stomach Neoplasms | 1997 |
Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins.
Topics: Antineoplastic Agents; Arsenicals; Blotting, Northern; Carcinoma, Squamous Cell; Carrier Proteins; Cell Membrane; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Antibody Technique, Indirect; Folate Receptors, GPI-Anchored; Humans; Liver Neoplasms; Membrane Proteins; Metals; Methotrexate; Neoplasm Proteins; Receptors, Cell Surface; Tumor Cells, Cultured | 1998 |
High incidence of brain metastases in patients treated with an M-VAC regimen for advanced bladder cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Follow-Up Studies; Humans; Incidence; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis; Radiography; Retrospective Studies; Severity of Illness Index; Survival Rate; Urinary Bladder Neoplasms; Vinblastine | 1998 |
[A case of renal pelvic cancer with recurrence of liver metastasis showing partial response by injection of methotrexate and intraarterial infusion of cisplatin and pirarubicin].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Injections, Intramuscular; Kidney Neoplasms; Kidney Pelvis; Leucovorin; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate | 1998 |
[Membranous lipodystrophy caused by chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Lipodystrophy; Liver Neoplasms; Methotrexate | 1998 |
[A case of unresectable pancreatic cancer responding to MTX/5-FU sequential therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Quality of Life | 1999 |
[A case of liver metastases from gastric cancer responding to induced hypertensive chemotherapy with angiotensin II].
Topics: Aged; Angiotensin II; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Drug Administration Schedule; Fluorouracil; Gastrectomy; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Mitomycin; Neoplasm Recurrence, Local; Stomach Neoplasms; Vasoconstrictor Agents | 1999 |
[A case report of hepatocellular carcinoma with hepatic and portal venous tumor thrombus and multiple intrahepatic metastasis who survived over 1 year after the operation with combined locoregional chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Neoplasm Invasiveness; Neoplastic Cells, Circulating; Portal Vein | 1999 |
Inhibition of P-glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Survival; Cloning, Molecular; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methotrexate; RNA, Antisense; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Vincristine | 2000 |
Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers; Butyrates; Cell Differentiation; Cell Division; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); DNA; Drug Synergism; Female; Fluorouracil; Glucose; Humans; Liver Neoplasms; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases; Protein-Tyrosine Kinases; Quinazolines; RNA, Messenger; Thiophenes; Thymidylate Synthase; Transplantation, Heterologous | 2001 |
Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor.
Topics: Antineoplastic Agents; Butyrates; Cell Cycle; Cell Differentiation; Cell Division; Colchicine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Hydroxyurea; Liver Neoplasms; Methotrexate; RNA; RNA, Messenger; Telomerase; Tumor Cells, Cultured | 2001 |
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with angiotensin-II and administration of tegafur/uracil].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Pancreatic Neoplasms; Tegafur; Uracil | 2001 |
[A case of advanced gastric cancer with multiple liver metastases partially responding to combination intra-arterial chemotherapy via the hepatic artery and abdominal aorta].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Stomach Neoplasms | 2001 |
[Clinical experience of intra-arterial chemotherapy for liver metastases of breast cancer patients].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catheters, Indwelling; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycin; Retrospective Studies | 2001 |
[Pharmacokinetics of "subselective" arterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Catheters, Indwelling; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Stomach Neoplasms | 2001 |
Hepatosplenic gammadelta T-cell lymphoma presenting with immune-mediated thrombocytopenia and hemolytic anemia (Evans' syndrome).
Topics: Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Autoimmune Diseases; Biopsy; Bleomycin; Blood Platelets; Bone Marrow; Cyclophosphamide; Doxorubicin; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Hepatomegaly; Humans; Hydrocortisone; Leucovorin; Liver Neoplasms; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Prednisone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Splenic Neoplasms; Splenomegaly; Syndrome; Thrombocytopenia; Vincristine | 2002 |
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Gastrectomy; Humans; Leucovorin; Liver Neoplasms; Lymph Node Excision; Male; Methotrexate; Middle Aged; Remission Induction; Stomach Neoplasms; Tegafur; Uracil | 2002 |
Brief report: successful therapy of a patient with infantile generalized myofibromatosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Eye Neoplasms; Humans; Infant; Liver Neoplasms; Male; Methotrexate; Myofibromatosis; Treatment Outcome; Vinblastine | 2002 |
Cure in a case of primary hepatic lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Ifosfamide; Liver Neoplasms; Lymphoma; Male; Methotrexate; Prednisolone; Tomography, X-Ray Computed; Vincristine | 2000 |
Cutaneous metastasis of gestational choriocarcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Drug Administration Schedule; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Pregnancy; Pregnancy Tests; Skin Neoplasms; Uterine Neoplasms | 2002 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methotrexate; Neoplasms, Experimental; Nitrosamines; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Vitamin B 12 | 1975 |
Chemotherapeutic drugs increase killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Vincristine | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin | 1975 |
Hepatic artery ligation and prolonged cytotoxic therapy in advanced primary and secondary liver tumours.
Topics: Adult; Aged; Antineoplastic Agents; Bilirubin; Biopsy; Catheterization; Female; Fluorouracil; Hepatic Artery; Humans; Leucovorin; Ligation; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Pulmonary Embolism | 1975 |
Effect of surgical and chemotherapeutic treatment on alpha-fetoprotein levels in patients with hepatocellular carcinoma.
Topics: alpha-Fetoproteins; Carmustine; Fetal Proteins; Humans; Liver Neoplasms; Methotrexate; Recurrence | 1976 |
[Treatment of primary and secondary liver tumors using a combination of chemotherapy and surgery].
Topics: Antineoplastic Agents; Carmustine; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methods; Methotrexate; Remission, Spontaneous; Vincristine | 1975 |
Treatment of hepatic metastases with a combination of hepatic artery infusion chemotherapy and external radiotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Catheterization; Cobalt Radioisotopes; Colonic Neoplasms; Female; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1978 |
Recent trends in chemotherapy of solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Cyclophosphamide; Esophageal Neoplasms; Female; Fluorouracil; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Methotrexate; Neoplasms; Pancreatic Neoplasms; Radiotherapy, High-Energy; Sarcoma; Urogenital Neoplasms | 1975 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Hepatic Artery; Humans; Liver Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Temporal Arteries; Time Factors | 1975 |
Future prospects for immunotherapy.
Topics: Animals; BCG Vaccine; Carcinoma, Hepatocellular; Dacarbazine; Guinea Pigs; Humans; Immunotherapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver Neoplasms; Melanoma; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Sarcoma | 1975 |
[Carcinoma of the liver in a child after seven-year complete remission of acute lymphoblastic leukaemia(author's transl)].
Topics: Carcinoma, Hepatocellular; Child; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Liver Neoplasms; Mercaptopurine; Methotrexate; Remission, Spontaneous; Time Factors | 1975 |
The experience with clinical application of hydron pouches in tumor chemotherapy.
Topics: Autopsy; Carcinoma, Hepatocellular; Child, Preschool; Cyclophosphamide; Drug Implants; Female; Gels; Humans; Infant; Liver; Liver Neoplasms; Male; Methacrylates; Methotrexate | 1975 |
[Tomizine--a new inhibitor of folate metabolism enzymes possessing an antitumor activity].
Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Folic Acid Antagonists; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Neoplasms, Experimental; Rats; Sarcoma 37; Sarcoma, Experimental; Thiazines | 1975 |
Regression of established tumors and induction of tumor immunity by intratumor chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Carmustine; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Graft Rejection; Guinea Pigs; Injections; Injections, Intraperitoneal; Liver Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
Combination chemotherapy with 5--fluorouracil, amethopterin (methotrexate) and prednisolone (FAP protocol) in the therapy of cholangiocarcinoma.
Topics: Adenoma, Bile Duct; Drug Therapy, Combination; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisolone | 1976 |
[Experiences with drug therapy of advanced metastatic carcinoma of the breast (author's transl)].
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thoracic Neoplasms; Vincristine | 1976 |
Enzyme pattern directed chemotherapy. The effects of combinations of methotrexate, 5-fluorodeoxyuridine and thymidine on rat hepatoma cells in vitro.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Depression, Chemical; Floxuridine; Liver Neoplasms; Methotrexate; Rats; Thymidine; Time Factors | 1976 |
Thymidylate synthetase activity in the Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Folic Acid; Liver Neoplasms; Male; Methotrexate; Methyltransferases; Neoplasms, Experimental; Puromycin; Rats; Tetrahydrofolates; Thymidylate Synthase | 1976 |
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Procarbazine; Skin Neoplasms | 1976 |
Growth rate of cultured Novikoff rat hepatoma cells as a function of the rate of thymidine and hypoxanthine transport.
Topics: Adenosine; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Dipyridamole; Guanosine; Hypoxanthines; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Rats; Thymidine; Thymine Nucleotides | 1977 |
Hepatoma in a child with methotrexate-induced hepatic fibrosis.
Topics: Carcinoma, Hepatocellular; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Liver; Liver Cirrhosis; Liver Neoplasms; Methotrexate | 1977 |
Chemotherapy studies in autochthonous rat tumors: hepatomas.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Rats; Time Factors | 1977 |
Treatment of primary liver cancer: response to regional chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Female; Floxuridine; Fluorouracil; Hepatectomy; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prognosis | 1979 |
Leucovorin in combination chemotherapy of breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone | 1977 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Animals; Chemical and Drug Induced Liver Injury; Chronic Disease; Contraceptives, Oral; Drug Hypersensitivity; Female; Halothane; Humans; Isoniazid; Liver; Liver Neoplasms; Methotrexate; Pharmaceutical Preparations; Tetracycline | 1979 |
Iatrogenic liver abscesses. A complication of hepatic artery ligation for tumor.
Topics: Arteriovenous Shunt, Surgical; Biliary Fistula; Bronchial Fistula; Female; Fluorouracil; Hepatic Artery; Humans; Iatrogenic Disease; Infusions, Intra-Arterial; Ligation; Liver Abscess; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rupture, Spontaneous | 1978 |
Treatment of hepatic metastases from breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Remission, Spontaneous; Testosterone; Time Factors | 1978 |
Antitumor properties of a new folate analog, 10-deaza-aminopterin, in mice.
Topics: Aminopterin; Animals; Carcinoma, Ehrlich Tumor; Drug Evaluation, Preclinical; Female; Folic Acid; Leukemia L1210; Liver Neoplasms; Male; Methotrexate; Mice; Neoplasms, Experimental; Plasmacytoma; Sarcoma 180 | 1978 |
Immunological overshoot phenomenon following cancer chemotherapy: significance in prognosis evaluation of solid tumors.
Topics: Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immune Adherence Reaction; Liver Neoplasms; Lung Neoplasms; Lymphocyte Activation; Melphalan; Methotrexate; Neoplasms; Ovarian Neoplasms; Thiotepa; Vincristine | 1975 |
Cyclic combination chemotherapy for metastatic breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous | 1977 |
Burkitt's lymphoma in an American youth: usefulness of radionuclide imaging in diagnosis and measuring the effects of treatment.
Topics: Adolescent; Burkitt Lymphoma; Cyclophosphamide; Humans; Liver Neoplasms; Male; Methotrexate; Pancreatic Neoplasms; Prednisone; Radionuclide Imaging; Thyroid Neoplasms; Vincristine | 1977 |
The role of nonspecific immunotherapy in the treatment of breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunity; Immunity, Cellular; Immunotherapy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Prognosis; Propionibacterium acnes | 1976 |
Hepatic artery ligation in treatment of carcinoid syndrome.
Topics: Aged; Angiography; Cyclophosphamide; Female; Fluorouracil; Hepatic Artery; Humans; Hydroxyindoleacetic Acid; Ileum; Intestinal Neoplasms; Ligation; Liver Neoplasms; Malignant Carcinoid Syndrome; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Serum Albumin, Radio-Iodinated | 1975 |
An effective low-dose intermittent cyclophosphamide, methotrexate, and 5-fluorouracil treatment regimen for metastatic breast cancer.
Topics: Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Neoplasm Metastasis; Peritoneal Neoplasms; Pleural Neoplasms; Skin Neoplasms | 1975 |
Intra arterial chemotherapy in malignant tumours of liver (a preliminary report).
Topics: Female; Fluorouracil; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate; Mitomycins | 1975 |
Combination chemotherapy for advanced breast cancer: response and effect on survival.
Topics: Adult; Bone Neoplasms; Breast Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Skin Neoplasms | 1976 |
Successful treatment of a primary endodermal sinus tumor of the liver.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Female; Hepatectomy; Humans; Liver Neoplasms; Mesonephroma; Methotrexate; Vincristine | 1992 |
Salvage chemotherapy in colorectal cancer patients with good performance status and young age after failure of 5-fluorouracil/leucovorin combination.
Topics: Adenocarcinoma; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Salvage Therapy; Survival Rate; Vincristine | 1992 |
[Effective treatment of liver metastasis and peritoneal dissemination of gastric cancer using intra-arterial therapy--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Drug Administration Schedule; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Norepinephrine; Peritoneal Neoplasms; Stomach Neoplasms | 1992 |
Long-term treatment in infantile choriocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Child, Preschool; Choriocarcinoma; Chorionic Gonadotropin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Embolization, Therapeutic; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasms, Multiple Primary; Prednisolone; Puberty, Precocious; Submandibular Gland Neoplasms; Vinblastine; Vincristine | 1992 |
[Hepatocellular carcinoma in a patient with psoriasis and methotrexate-induced cirrhosis].
Topics: Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Methotrexate; Middle Aged; Psoriasis | 1991 |
Low-dose methotrexate therapy for hepatoblastoma.
Topics: Carcinoma, Hepatocellular; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Liver Neoplasms; Male; Methotrexate | 1991 |
[Histopathologic study on resected hepatocellular carcinoma after transcatheter hepatic arterial chemo-embolization].
Topics: Adult; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms; Male; Methotrexate; Microspheres; Middle Aged; Mitomycin | 1991 |
The effect of methotrexate on the folate coenzyme pools in human hepatoma cells in culture.
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Deoxyuridine; Folic Acid; Glycine; Humans; Kinetics; Liver Neoplasms; Methotrexate; Tritium; Tumor Cells, Cultured | 1991 |
Folate analogues. 33. Synthesis of folate and antifolate poly-gamma-glutamates by [(9-fluorenylmethoxy)oxy]carbonyl chemistry and biological evaluation of certain methotrexate polyglutamate polylysine conjugates as inhibitors of the growth of H35 hepatoma
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry; Chemistry, Physical; Drug Resistance; Extracellular Space; Folic Acid Antagonists; Humans; In Vitro Techniques; Liver Neoplasms; Methotrexate; Polyglutamic Acid; Tumor Cells, Cultured | 1990 |
Primary non-Hodgkin's lymphoma of liver with humoral hypercalcaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Hypercalcemia; Leucovorin; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Methotrexate; Prednisone; Vincristine | 1990 |
Cytoreductive surgery in disseminated non-seminomatous germ cell tumours of testis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Teratoma; Testicular Neoplasms; Vincristine | 1991 |
Ifosfamide, methotrexate and 5-fluorouracil for pretreated advanced breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Fluorouracil; Hematopoiesis; Humans; Ifosfamide; Liver Neoplasms; Mesna; Methotrexate; Middle Aged; Risk Factors; Survival Analysis | 1991 |
Evaluation of prognostic factors for 233 patients with recurrent advanced breast cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycin; Prognosis; Tamoxifen; Tegafur; Vincristine | 1991 |
[Hepatic arterial infusion chemotherapy and loco-regional treatment and irradiation of pancreas tumor in non-resectable pancreas cancer with liver metastases].
Topics: Administration, Oral; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Leucovorin; Liver Neoplasms; Methotrexate; Pancreatic Neoplasms; Radiotherapy, High-Energy | 1991 |
Prognostic factors for survival of patients with advanced urothelial tumors treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy.
Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Bone Neoplasms; Cisplatin; Doxorubicin; Hemoglobins; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Prognosis; Risk; Survival Rate; Urinary Bladder Neoplasms; Vinblastine | 1991 |
"Poor prognosis" metastatic gestational trophoblastic disease: the prognostic significance of the scoring system in predicting chemotherapy failures.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Combined Modality Therapy; Dactinomycin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Pregnancy; Prognosis; Remission Induction; Retrospective Studies; Trophoblastic Neoplasms; Uterine Neoplasms | 1990 |
Toxicities of trichosanthin and alpha-momorcharin, abortifacient proteins from Chinese medicinal plants, on cultured tumor cell lines.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Division; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cisplatin; Drugs, Chinese Herbal; Fluorouracil; Humans; Liver Neoplasms; Melanoma; Methotrexate; Plant Proteins; Progesterone; Ribosomal Proteins; Ribosome Inactivating Proteins; Trichosanthin; Tumor Cells, Cultured | 1990 |
Rapid chemosensitivity assay with human normal and tumor cells in vitro.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Fibroblasts; Fluorouracil; Humans; Keratinocytes; Liver Neoplasms; Melanocytes; Melanoma; Methotrexate; Neutral Red; Time Factors; Tumor Cells, Cultured | 1990 |
Neoadjuvant methotrexate, vinblastine, doxorubicin, and cisplatin for locally advanced transitional cell carcinoma of the bladder.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prostatectomy; Retrospective Studies; Urinary Bladder Neoplasms; Vinblastine | 1990 |
Primary hepatic lymphoma in an adolescent treated with hepatic lobectomy and chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Combined Modality Therapy; Cyclophosphamide; Cytoplasm; Hepatectomy; Humans; Liver Neoplasms; Lymphoma; Male; Methotrexate; Prednisone; Remission Induction; Vincristine | 1990 |
Usefulness and limitations of methotrexate, vinblastine, doxorubicin and cisplatin for the treatment of advanced urothelial cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Time Factors; Urologic Neoplasms; Vinblastine | 1990 |
[A case of right renal pelvic and ureter cancer with hepatic metastasis showing complete response by M-VAC].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Humans; Kidney Neoplasms; Kidney Pelvis; Liver Neoplasms; Male; Methotrexate; Remission Induction; Ureteral Neoplasms; Vinblastine | 1990 |
Hepatocellular carcinoma in a long-term survivor of acute lymphocytic leukemia.
Topics: Adult; alpha 1-Antitrypsin; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Liver Neoplasms; Mercaptopurine; Methotrexate; Neoplasm Proteins; Neoplasms, Multiple Primary | 1987 |
[Conservative treatment of malignant liver tumors].
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Particle Accelerators; Radiotherapy Dosage; Tegafur | 1989 |
[Locoregional chemotherapy of liver tumors].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusion Pumps; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins | 1989 |
[Preventive effects of intra-arterial infusion chemotherapy of liver metastasis in non-resectable pancreatic cancer].
Topics: Alprostadil; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Humans; Infusions, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Portal Vein | 1989 |
[Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Stomach Neoplasms | 1989 |
[Bone marrow necrosis in a patient with metastatic breast cancer in chemotherapy with chlorambucil, methotrexate and prednisone].
Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chlorambucil; Female; Humans; Liver Neoplasms; Methotrexate; Middle Aged; Necrosis; Prednisone | 1989 |
[Ablative hormone therapy and chemotherapy of metastatic breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Liver Neoplasms; Lymph Node Excision; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Ovariectomy | 1989 |
Prognostic factors in patients with hepatocellular carcinoma receiving systemic chemotherapy. Identification of two groups of patients with prospects for prolonged survival.
Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Doxorubicin; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Streptozocin; Time Factors | 1985 |
High-risk metastatic gestational trophoblastic disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Combined Modality Therapy; Dactinomycin; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Peptide Fragments; Pregnancy; Retrospective Studies; Risk; Trophoblastic Neoplasms; Uterine Neoplasms | 1985 |
Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms; Vinblastine | 1989 |
[Rationale and current results of loco-regional chemotherapy in hepatic metastases of colorectal carcinoma].
Topics: Antineoplastic Agents; Carmustine; Cisplatin; Colorectal Neoplasms; Doxorubicin; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Methotrexate; Mitomycin; Mitomycins; Models, Biological; Prognosis | 1987 |
Hepatic metastases in gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Follow-Up Studies; Humans; Leukopenia; Liver Neoplasms; Methotrexate; Middle Aged; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1986 |
Poor prognosis metastatic gestational trophoblastic disease: experience with moderate dose methotrexate plus folinic acid rescue as initial therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chlorambucil; Chorionic Gonadotropin; Combined Modality Therapy; Dactinomycin; Female; Humans; Hysterectomy; Leucovorin; Liver Neoplasms; Methotrexate; Pregnancy; Prognosis; Time Factors; Trophoblastic Neoplasms; Uterine Neoplasms; Vinblastine | 1986 |
Therapy for metastatic colorectal cancer with hepatic artery infusion chemotherapy using a subcutaneous implanted pump.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Peptic Ulcer; Prostheses and Implants; Rectal Neoplasms | 1985 |
[Study on microspheres for embolization of the hepatic artery].
Topics: Animals; Delayed-Action Preparations; Dogs; Embolization, Therapeutic; Fluorouracil; Gelatin; Hepatic Artery; Liver Neoplasms; Methotrexate; Microspheres; Polyvinyl Alcohol | 1988 |
[4-component chemotherapy and radiation therapy of breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Radiotherapy Dosage; Time Factors | 1986 |
[A case of long-term survival of liver metastasis of breast cancer successfully treated with chemotherapy and endocrine therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Methotrexate; Middle Aged; Tamoxifen; Tegafur | 1985 |
[Adjuvant chemotherapy of intraocular malignant melanoma. Apropos of 20 cases].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dacarbazine; Eye Neoplasms; Female; Humans; Liver Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Procarbazine; Thiotepa; Vinblastine | 1985 |
Acute renal failure and death following sequential intermediate-dose methotrexate and 5-FU: a possible adverse effect due to concomitant indomethacin administration.
Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Indomethacin; Liver Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
A phase II study of sequential methotrexate and fluorouracil in advanced colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Evaluation; Fluorouracil; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms | 1985 |
[A case of esophageal carcinoma with liver metastasis treated with cisplatin].
Topics: Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Esophagoscopy; Female; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Tomography, X-Ray Computed | 1985 |
I foetoprotein and children's cancer.
Topics: Alpha-Globulins; Carcinoma, Hepatocellular; Fetal Proteins; Liver Neoplasms; Male; Methotrexate; Prognosis; Retroperitoneal Neoplasms; Sacrococcygeal Region; Teratoma; Testicular Neoplasms | 1971 |
Serum alpha-fetoprotein as a biochemical marker for hepatocellular carcinoma.
Topics: Adolescent; Adult; Age Factors; Alpha-Globulins; Blood Transfusion; Carcinoma, Hepatocellular; Female; Fetal Proteins; Fluorouracil; Hepatectomy; Humans; Immunodiffusion; Liver Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Sex Factors; Time Factors | 1972 |
Sequential gonadoblastoma and choriocarcinoma.
Topics: Adult; Autopsy; Biopsy; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Endometrium; Female; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Pregnancy | 1973 |
The treatment of hepatic metastases by long-term chemotherapeutic infusions.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Evaluation Studies as Topic; Female; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Liver Neoplasms; Male; Methods; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1970 |
Continuous arterial infusion chemotherapy. Experience with 44 cases.
Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Catheterization; Chloramphenicol; Facial Neoplasms; Fever; Fluorouracil; Head and Neck Neoplasms; Humans; Infections; Infusions, Parenteral; Leucovorin; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Palliative Care; Penicillins; Stomach Neoplasms; Thoracic Neoplasms | 1967 |
[Loco-regional and sequential chemotherapy of advanced cancer].
Topics: Adult; Carcinoma; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Dysgerminoma; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Palliative Care; Rectal Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms; Vinblastine | 1968 |
Oral methotrexate therapy of gastrointestinal carcinoma.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Humans; Intestinal Neoplasms; Liver Neoplasms; Methotrexate; Palliative Care; Pancreatic Neoplasms; Stomach Neoplasms | 1970 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
The effect of cytostatic therapy with cyclophosphamide alone or in combination with methotrexate on the phytohaemagglutinin lymphocyte culture and on the immunoglobulins.
Topics: Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Female; gamma-Globulins; Humans; Immunoglobulins; Lectins; Liver Neoplasms; Lung Neoplasms; Lymphocytes; Male; Methotrexate; Middle Aged; Prostatic Neoplasms | 1970 |
[A new treatment of hepatic metastases].
Topics: Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate | 1966 |
An evaluation of 51 patients with hepatic artery infusion.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Melphalan; Methotrexate; Neoplasm Metastasis | 1966 |
[Chemotherapeutic treatment of liver metastases as a function of their spontaneous evolution].
Topics: Floxuridine; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis | 1969 |
Practical aspects of investigation and treatment of colorectal cancer.
Topics: Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Humans; Infusions, Parenteral; Liver Function Tests; Liver Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Neoplasm Metastasis; Proctoscopy; Prognosis; Rectal Neoplasms; Sex Factors | 1972 |
The metabolic fate of tritiated methotrexate. II. Absorption and excretion in man.
Topics: Adult; Blood; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Child; Child, Preschool; Choriocarcinoma; Chromatography; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Liver Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Pregnancy; Testicular Neoplasms; Tritium; Urine | 1965 |
Infusion chemotherapy in hepatoma and metastatic liver tumors.
Topics: Adenocarcinoma; Adolescent; Aged; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Parenteral; Leucovorin; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Sigmoid Neoplasms | 1967 |
Resection of metastases in Wilms' tumor: a report of three cases cured of pulmonary and hepatic metastases.
Topics: Child, Preschool; Chlorambucil; Cobalt Isotopes; Dactinomycin; Female; Humans; Infant; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Nephrectomy; Radiography; Wilms Tumor | 1968 |
Infusion of liver tumours.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Radioisotopes | 1968 |
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine | 1969 |
Structural and regulatory aspects of enzymes in chemotherapy.
Topics: Animals; Asparaginase; Carcinoma, Hepatocellular; Cell Membrane; Humans; Liver; Liver Neoplasms; Mammals; Methotrexate; Triazines | 1969 |
Malignant neural elements in a benign cystic teratoma. A case report.
Topics: Adult; Antineoplastic Agents; Bone Marrow Diseases; Cyclophosphamide; Dactinomycin; Dermoid Cyst; Female; Glioblastoma; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Radiography; Teratoma; Ureteral Neoplasms; Vincristine | 1971 |
[New route of regulating folic acid metabolism in experimental chemotherapy of leukoses and malignant neoplasms].
Topics: Animals; Carcinoma, Hepatocellular; Cycloserine; Female; Folic Acid; Leukemia, Experimental; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Methotrexate; Mice; Neoplasms, Experimental; Pyridoxal Phosphate; Rats; Spleen; Tetrahydrofolate Dehydrogenase; Transferases | 1971 |
Liver tumours in infancy and childhood.
Topics: Adolescent; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Female; Hamartoma; Hepatectomy; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Mesenchymoma; Methotrexate; Rhabdomyosarcoma; Vincristine | 1971 |
Stabilization of dihydrofolate reductase by inhibitors in vivo and in vitro.
Topics: Animals; Biodegradation, Environmental; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Cycloheximide; Drug Stability; Electrophoresis; Enzyme Activation; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Liver Neoplasms; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triamterene; Trimethoprim | 1971 |
The apparent induction of thymidylate synthetase by amethopterin.
Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Methotrexate; Methyltransferases; Neoplasms, Experimental; Quinazolines; Rats; Thymine Nucleotides; Uracil Nucleotides | 1971 |
The chemotherapy of gestational trophoblastic disease: principles of clinical management.
Topics: Brain Neoplasms; Choriocarcinoma; Dactinomycin; Female; Gonadotropins; Humans; Hydatidiform Mole; Hysterectomy; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pelvic Neoplasms; Pregnancy; Pregnancy Complications; Trophoblastic Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1972 |
Capillary tube scanning applied to cell growth kinetics.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Biology; Cell Count; Cells; Cells, Cultured; Hypoxanthines; Kinetics; Liver Neoplasms; Lymphoma; Methotrexate; Mice; Mitosis; Neoplasms, Experimental; Photometry; Rats; Thymidine | 1972 |
Preliminary clinical trials of dichloromethotrexate (NSC-29630) in hepatocellular carcinoma.
Topics: Adolescent; Adult; Aged; Aldehydes; Carcinoma, Hepatocellular; Chlorine; Diarrhea; Erythrocyte Count; Female; Hepatic Artery; Humans; Infusions, Parenteral; Injections, Intravenous; Leukocyte Count; Liver; Liver Function Tests; Liver Neoplasms; Male; Methotrexate; Middle Aged; Oxidoreductases | 1972 |
Treatment of metastatic trophoblastic disease: good and poor prognosis.
Topics: Brain Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Follow-Up Studies; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Hysterectomy; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Pregnancy; Prognosis; Remission, Spontaneous; Time Factors; Trophoblastic Neoplasms | 1973 |
The surgical management of primary hepatocellular carcinoma in Uganda.
Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Catheterization; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Liver Neoplasms; Male; Methotrexate; Middle Aged; Uganda | 1973 |
Letter: On the source of "minor thymine" in DNA from a Novik off rat hepatoma cell line.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Cytosine; Deamination; Deoxycytidine; DNA; Liver; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Rats; Thymidine; Thymine; Tritium | 1973 |
A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell-Free System; Cytoplasm; Deoxyribonucleotides; Drug Resistance, Microbial; Evaluation Studies as Topic; Filtration; Fluorine; Kinetics; Lacticaseibacillus casei; Liver Neoplasms; Methods; Methotrexate; Methyltransferases; Neoplasms, Experimental; Rats; Spectrophotometry; Tetrahydrofolates; Thymidylate Synthase; Tritium; Uracil Nucleotides | 1974 |
[Combined drug-surgical treatment in primary and secondary liver tumors].
Topics: Carcinoma, Hepatocellular; Drug Therapy, Combination; Floxuridine; Humans; Injections, Intra-Arterial; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Postoperative Complications; Prognosis; Vincristine | 1974 |
Major hepatic resection using vascular isolation and hypothermic perfusion.
Topics: Cyclophosphamide; Dactinomycin; Fluorouracil; Hepatectomy; Hepatic Veins; Humans; Hypothermia, Induced; Ligation; Liver Circulation; Liver Neoplasms; Methotrexate; Monitoring, Physiologic; Perfusion; Portal Vein; Postoperative Complications; Radionuclide Imaging; Subphrenic Abscess; Surgical Wound Infection; Technetium; Venae Cavae | 1974 |
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cattle; Depression, Chemical; DNA, Neoplasm; Female; Fluorouracil; Humans; In Vitro Techniques; Iodoacetates; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; Mechlorethamine; Methotrexate; Mice; Neoplasms; Phenylalanine; Succinate Dehydrogenase; Thymidine; Tritium | 1974 |
Drug resistant choriocarcinoma presenting with hepatomegaly.
Topics: Adult; Autopsy; Choriocarcinoma; Drug Resistance; Female; Hemoperitoneum; Hepatomegaly; Humans; Leucovorin; Liver Circulation; Liver Neoplasms; Methotrexate; Pregnancy; Radionuclide Imaging | 1973 |
Results of 27 cases with hepatic metastases treated by combination chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Jaundice; Liver; Liver Neoplasms; Methotrexate; Neoplasm Metastasis; Radionuclide Imaging; Rectal Neoplasms; Vincristine | 1972 |
Five-drug combination chemotherapy for disseminated adenocarcinoma.
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Ovarian Neoplasms; Parotid Neoplasms; Prednisone; Time Factors; Vincristine | 1972 |
Combination therapy of solid tumors using 1,3-bis(2-chloroethyl)-1-nitrosourea (NCNU), vincristine, methotrexate, and 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Carmustine; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasms; Thyroid Neoplasms; Uterine Neoplasms; Vincristine | 1973 |
Treatment of primary and secondary liver cancer by hepatic artery ligation and infusion chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Female; Follow-Up Studies; Hepatic Artery; Humans; Ligation; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Postoperative Complications | 1973 |
The treatment of jaundice due to liver metastases by quadruple chemotherapy.
Topics: Aged; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Jaundice; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Vincristine | 1973 |
Methotrexate in liver and bile after intravenous dosage in man.
Topics: Adult; Bile; Humans; Injections, Intravenous; Liver; Liver Neoplasms; Methotrexate; Middle Aged; Models, Biological; Tritium | 1973 |
Intra-arterial cancer chemotherapy with combined anticancer agents.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Leukopenia; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Connective Tissue; Pyridoxal Phosphate; Stomach Neoplasms; Vinblastine; Vincristine | 1973 |
Cyclical combination chemotherapy for advanced breast carcinoma.
Topics: Adrenalectomy; Adult; Alopecia; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Liver; Liver Neoplasms; Lung Neoplasms; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Metastasis; Prednisone; Thrombocytopenia | 1974 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; Fluorouracil; Gold Colloid, Radioactive; Humans; Liver Abscess, Amebic; Liver Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Thiotepa | 1969 |
Chemotherapy for metastatic colorectal liver carcinoma by intra-aortic infusion.
Topics: Antineoplastic Agents; Aorta, Abdominal; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Rectal Neoplasms; Remission, Spontaneous; Retrospective Studies; Time Factors; Vinblastine; Vincristine | 1971 |
Metastatic choriocarcinoma as a complication of pregnancy.
Topics: Adult; Autopsy; Choriocarcinoma; Female; Gastrointestinal Hemorrhage; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pregnancy; Pregnancy Complications; Uterine Neoplasms | 1970 |
Historic and current intra-arterial chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Extremities; Female; Fluorouracil; Follow-Up Studies; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Leucovorin; Liver Neoplasms; Male; Mechlorethamine; Methotrexate; Neoplasms; Pelvic Neoplasms; Thoracic Neoplasms | 1970 |
Clinical and experimental evaluation of urinary histidine derivatives as an index of folic acid metabolism. II. The observation in neoplastic diseases with or without methotrexate administration.
Topics: Adult; Aged; Animals; Blood Cell Count; Blood Platelets; Dogs; Female; FIGLU Test; Folic Acid; Histidine; Humans; Leukocyte Count; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms | 1969 |
Infusion chemotherapy.
Topics: Antineoplastic Agents; Arm; Carcinoma, Squamous Cell; Colonic Neoplasms; Head; Head and Neck Neoplasms; Humans; Leg; Liver Neoplasms; Methods; Methotrexate; Neoplasms | 1970 |
Combination chemotherapy in the treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Drug Synergism; Female; Hodgkin Disease; Humans; Hypersensitivity, Delayed; Liver Neoplasms; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine | 1970 |
A radioisotopic method for determining optimum non-surgical therapy for advanced cancer. II. Clinical experience.
Topics: Adenocarcinoma; Breast Neoplasms; Diethylstilbestrol; Female; Fluorouracil; Fluoxymesterone; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Male; Methods; Methotrexate; Neoplasm Metastasis; Phosphorus Isotopes; Prednisone | 1968 |
Chemotherapy for liver cancer by protracted ambulatory infusion.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusions, Parenteral; Liver Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Rectal Neoplasms | 1965 |