methotrexate has been researched along with Leukopenia in 238 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 151 (63.45) | 18.7374 |
| 1990's | 39 (16.39) | 18.2507 |
| 2000's | 27 (11.34) | 29.6817 |
| 2010's | 15 (6.30) | 24.3611 |
| 2020's | 6 (2.52) | 2.80 |
| Authors | Studies |
|---|---|
| Chekhonin, VP; Li, H; Li, S; Li, Z; Lin, Y; Ma, W; Peltzer, K; Wang, J; Wang, X; Wu, H; Xu, G; Xu, Y; Xue, Y; Zhang, C; Zhang, J | 1 |
| Lyu, H; Solomon, DH; Vanni, KMM | 1 |
| Ino, K; Kajiyama, H; Kikkawa, F; Kotani, T; Niimi, K; Nishino, K; Sato, S; Suzuki, S; Yamamoto, E | 1 |
| Li, J; Li, R; Lu, X; Zhang, B; Zhang, Y | 1 |
| Chaitoff, A; Ellis, A; Fernandez, AP; Havele, SA; Khanna, U; Langford, CA; Parambil, J | 1 |
| Aggarwal, A; Dhawan, V; Dhir, V; Gupta, R; Jain, S; Khullar, A; Leishangthem, B; Maurya, S; Naidu, S; Sharma, A; Sharma, SK | 1 |
| Abdel-Salam, IM; Abdel-Warith, AM; Ahmed, WA; Allahloubi, NMA; Gaafar, RM; Hussein, MM; Salem, SE | 1 |
| Cacciavillano, W; Rose, A; Scopinaro, M; Villegas Rubio, JA; Zubizarreta, P | 1 |
| Abrahamsson, J; Bechensteen, AG; Frandsen, TL; Harila-Saari, A; Heldrup, J; Jonsson, OG; Lausen, B; Levinsen, M; Nygaard, U; Rosthøj, S; Schmiegelow, K; Weinshilboum, RM | 1 |
| Alamillo, I; Lopez, B; Medina-Sanson, A; Moreno-Galván, M; Moreno-Guerrero, S; Ramírez-Pacheco, A | 1 |
| Frandsen, TL; Grell, K; Hjalgrim, LL; Nersting, J; Nielsen, SN; Schmiegelow, K | 1 |
| Deckert, M; Feuerhake, F; Finke, J; Ihorst, G; Illerhaus, G; Marks, R; Müller, F; Ostertag, C | 1 |
| Guan, ZZ; Lin, H; Ling, JY; Luo, WB; Peng, RJ; Sun, XF; Xia, Y; Xiang, XJ; Zhen, ZJ; Zheng, L | 1 |
| Callen, JP; Kalajian, AH; Van Meter, JR | 1 |
| Baccarani, M; Broccoli, A; De Renzo, A; Derenzini, E; Fina, MP; Gandolfi, L; Martelli, M; Pellegrini, C; Perrotti, A; Petti, MC; Pileri, SA; Stefoni, V; Venturini, F; Zaja, F; Zinzani, PL | 1 |
| Boyle, B; Crandall, W; Kumar, S; Mackner, L; Moses, J; Ross, C | 1 |
| Goto, N; Hayashi, K; Ohtsu, F; Sakakibara, J; Yano, R | 1 |
| Bari, M; Ciruelos, E; De Benedictis, E; Dittrich, C; Gaion, F; Gomez, P; Lluch, A; Luca, G; Mansutti, M; Morandi, P; Pavesi, L; Semiglazov, V; Valagussa, P; Zamagni, C; Zambetti, M | 1 |
| Ahmed, M; Gilani, ST; Khan, DA; Khan, FA | 1 |
| Elsner, K; Haase, R; Körholz, D; Kramm, CM; Mauz-Körholz, C; Merkel, N; Stiefel, M | 1 |
| Fukushima, N; Hasegawa, Y; Hashimoto, C; Hyo, R; Ishida, F; Isobe, Y; Ito, Y; Izutsu, K; Kawa, K; Kimura, H; Kobayashi, H; Maeda, Y; Nakamura, S; Okamura, S; Oshimi, K; Suzuki, R; Suzumiya, J; Takizawa, J; Yamaguchi, M | 1 |
| Kaun, S; Kiewe, P; Klasen, H; Korfel, A; Martus, P; Möhle, R; Rauch, M; Röth, A; Roth, P; Thiel, E; Weller, M | 1 |
| Apibal, S; Hongeng, S; Koomdee, N; Pakakasama, S | 1 |
| El-Serag, HB; Hou, JK; Kramer, JR; Richardson, P; Sansgiry, S | 1 |
| Binard, A; Devauchelle-Pensec, V; Fautrel, B; Flipo, RM; Jousse-Joulin, S; Le Boëdec, M; Le Loët, X; Marhadour, T; Ménard, JF; Saraux, A | 1 |
| Boettcher, H; Costard-Jäckle, A; Cremer, J; Hirt, SW; Möller, F | 1 |
| ALEXANDRE, GP; DAMMIN, GJ; MURRAY, JE; NOLAN, B | 1 |
| DONOHUE, DM; FOYE, LV; JACOBS, EM; PAPAC, RJ | 1 |
| ECKERT, GE; O'ROURKE, RA | 1 |
| AUERBACH, R; BLACK, RL; BUNIM, JJ; EISEN, AZ; O'BRIEN, WM; VANSCOTT, EJ | 1 |
| BEAHRS, OH; CALDAROLA, VT; HARRISON, EG | 1 |
| AUERBACH, R | 1 |
| DERBES, VJ | 1 |
| BLENDIS, LM; SHRANK, AB | 1 |
| Kimura, H; Kita, E; Konishi, M; Mikasa, K; Narita, N; Takahashi, K; Yoshimoto, E | 1 |
| Akaza, H; Hayashi, H; Hinotsu, S; Kawai, K; Miyanaga, N; Miyazaki, J; Onozawa, M; Shimazui, T; Tsukamoto, S | 1 |
| Chen, YX; Mao, YY; Xie, X | 1 |
| Edelheit, BS; Lehman, TJ; Onel, KB | 1 |
| de Dios Luna, J; Hidalgo-Tenorio, C; Jiménez-Alonso, J; Martínez-Brocal, A; Sabio, JM; Tallada, M | 1 |
| Hondoh, H; Morii, K; Onda, K; Shinbo, Y; Takahashi, H; Takeuchi, S; Tamura, T; Tanaka, R; Yamanaka, R | 1 |
| Gou, HF; Hou, M; Li, L; Qiu, M; Yan, X; Zhu, J | 1 |
| Sun, ZJ; Wan, XR; Xiang, Y; Yang, XY | 1 |
| Khanam, A; Mehreen, L | 1 |
| Balduzzi, A; Cardillo, A; Colleoni, M; Ghisini, R; Goldhirsch, A; Orlando, L; Peruzzotti, G; Pietri, E; Rocca, A; Torrisi, R | 1 |
| Amory, JK; Kalus, RM; Saint, S; Shojania, KG | 1 |
| Katori, H; Taguchi, T; Tsukuda, M | 1 |
| Hirobe, M; Honma, I; Itoh, N; Maeda, T; Masumori, N; Takahashi, A; Tsukamoto, T | 1 |
| de Groot, K; Gross, WL; Hellmich, B; Iking-Konert, C; Manger, K; Metzler, C; Miehle, N; Reinhold-Keller, E | 1 |
| Kinukawa, N; Koga, H; Naito, S; Tsunoda, T; Yamamoto, K; Yokomizo, A | 1 |
| Hayashi, Y; Kobayashi, R; Kondo, T; Kurata, T; Kutsuzawa, T; Shioya, S; Sonoda, Y; Takasaki, Y; Tamaya, S; Yamauchi, T | 1 |
| Benz, C; Cadman, E; Tattelman, E; Tillis, T | 1 |
| Chebotareva, LI; Garin, AM; Guznov, GI; Moroz, LV; Prorokov, VV | 1 |
| Coleman, M; Gordon, B; Hollister, D; Silver, RT | 1 |
| Brema, F; Campora, E; Porcile, G; Rosso, R; Santi, L; Stefani, G | 1 |
| Camacho, F; Cinberg, J; Kaplan, BH; Lerner, H; Vogl, SE | 1 |
| Abrams, J; Espana, P; Haidak, D; Schein, P; Smith, F; Ueno, W; Woolley, P | 1 |
| Ahmed, T; Harper, HD; Kemeny, NE; Michaelson, RA; Yip, LC | 1 |
| Moertel, CG; O'Connell, MJ; Reitemeier, RJ; Rubin, J | 1 |
| Aisner, J; Van Echo, DA; Whitacre, M; Wiernik, PH | 1 |
| Capizzi, RL; Carney, C; Delaney, D; Kahn, L; Kirsch, M; Lipper, S; Neijstrom, ES; Rudnick, SA | 1 |
| Batley, F; Chen, TY; Cohen, M; Kakos, G; Kilman, J; Mountain, CF; Sealy, R; Stanley, K; Tucker, RD; Vasko, J; Vincent, RG; Williams, TE; Wilson, HE | 1 |
| Chen, TT; Costanzi, JJ; Livingston, RB; McGavran, M; Mira, JG; Samson, M | 1 |
| Abel, U; Beyer, JH; Herrmann, R; Holzmann, K; Schmieder, A; Spehn, J; von Franqué, U | 1 |
| Beron, G; Jürgens, H; Winkler, K | 1 |
| Archibald, SD; Browman, GP; Hryniuk, WM; Kiehl, K; Levine, MN; Russell, R; Young, JE | 1 |
| Aisner, J; Cortes, E; Glidewell, OJ; Kennedy, BJ; Leone, LA; Perloff, M; Silver, RT; Tormey, DC; Weinberg, VE; Weiss, RB | 1 |
| Beck, TM; Curtis, PW; Hart, NE; Smith, CE; Woodard, DA | 1 |
| Adachi, K; Horikoshi, N; Ikeda, K; Inagaki, J; Inoue, K; Nakada, H; Ogawa, M; Tada, A; Usui, N; Yamazaki, H | 1 |
| Chahinian, AP; Green, G; Holland, JF | 1 |
| Blumenschein, GR; Buzdar, AU; Distefano, A; Pinnamaneni, K; Yap, HY | 1 |
| Banerjee, TK; Greenlaw, RH; Hoehn, JL; Jacoby, C | 1 |
| Armata, J; Balwierz, W; Bogusławska-Jaworska, J; Ciepielewska, D; Kaczmarek-Kanold, M; Kościelniak, E; Ochocka, M; Radwańska, U; Sońta-Jakimczyk, D; Sroczyńska, M | 1 |
| Chabner, BA; DeVita, VT; Fisher, RI; Hubbard, SM; Longo, DL; Wesley, R; Young, RC | 1 |
| Jungi, WF; Senn, HJ; Waibel, PJ | 1 |
| Evans, WK; Gospodarowicz, M; Tannock, IF | 1 |
| Boutseleis, J; Neidhart, JA; Talley, R | 1 |
| Lee, YT | 2 |
| Golomb, HM; Sweet, DL | 1 |
| Brennan, MF; Devereux, DF; Shamberger, RC | 1 |
| Chabner, BA; Donehower, RC; Schilsky, RL | 1 |
| Marcellini, G; Marzetti, L; Midulla, C | 1 |
| Demitrish, M; Duffin, H; Enochs, K; Groshko, G; Lockhard, C; Maniscalco-Greb, E; Vaughn, CB | 1 |
| Baehner, R; Hammond, GD; Nesbit, ME; Sather, H; Siegel, SE | 1 |
| Advani, SH; Fakih, AR; Gopal, R; Mehta, AR; Nair, CN; Rao, MR; Sanghvi, VD | 1 |
| Balcueva, E; Dimitrov, NV; Egner, J; Suhrland, LG | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Rygård, J | 1 |
| Berenzweig, M; Kaplan, BH; Lanham, R; Richard, J; Solan, A; Vogl, SE | 1 |
| Kuwabara, K; Machida, K; Miyoshi, I; Niiya, K; Taguchi, H | 1 |
| Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Arimori, S; Hoshina, Y; Ichikawa, Y; Moriuchi, J; Nakamura, Y | 1 |
| Igawa, M; Kadena, H; Ueda, M; Usui, T | 1 |
| Kawakami, M; Kobayashi, S; Niwakawa, M; Ogawa, A; Okaneya, T; Tsuruta, T | 1 |
| Kondo, I; Miura, T; Murai, T; Shimura, H | 1 |
| Furuta, H; Miyabe, K; Miyaguchi, M; Sakai, S; Takeda, J; Uozumi, N | 1 |
| Cury, Y; Sudo, LS; Teixeira, CF | 1 |
| Ambrosini, G; Barni, S; Caffo, O; Frontini, L; Gasparini, G; Guglielmi, RB; Testolin, A | 1 |
| Ito, T; Komatsu, Y; Moriya, N; Ogasawara, H; Saito, S; Sakata, Y; Sugimoto, N; Tamura, Y; Tsushima, K; Yamada, Y | 1 |
| Ashley, S; Holborn, J; Jones, AL; Smith, IE | 1 |
| Dale, P; McKendry, RJ | 1 |
| Burghouts, JT; Conroy, T; de Graeff, A; Fickers, M; Lalisang, F; Paillot, B; Roelofs, EJ; Wagener, DJ; Wils, J | 1 |
| Bertino, J; Casper, E; Christman, K; Colofiore, J; Kelsen, D; Martin, DS; Quan, V; Saltz, L; Schwartz, GK | 1 |
| Farhi, DC; Rosenthal, NS | 1 |
| de Mulder, P; Oosterhof, GO; Witjes, JA; Wullink, M | 1 |
| de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH | 1 |
| Kvinnsland, S | 1 |
| Blomqvist, C; Joensuu, H; Lundin, J; Poikonen, P; Saarto, T | 1 |
| Akimov, MA; Gershanovich, ML | 1 |
| Feldman, BM; Krafchik, BR; Laxer, RM; Uziel, Y; Yeung, RS | 1 |
| Bang, SM; Bang, YJ; Byun, JH; Chang, HM; Choe, KJ; Heo, DS; Kim, NK; Kim, SR; Lee, KH; Noh, DY | 1 |
| Blomqvist, C; Joensuu, H; Poikonen, P | 1 |
| Hosaka, M; Ikeda, I; Kawakami, S; Kubota, Y; Masuda, M; Noguchi, S; Ohuchi, H; Saito, K; Takase, K; Yao, M | 1 |
| Katoh, S; Murayama, T; Nakazaki, S | 1 |
| Fraser, AG; Jewell, DP; McGovern, D; Morton, D; Travis, S | 1 |
| Dubost, JJ; Fournier, P; Guillemot, C; Ristori, JM; Soubrier, M | 1 |
| Holoye, PY; Johnson, DE; Samuels, ML | 1 |
| Bertrand, M; De Jager, R; Kenis, Y; Vanhaelen, C | 1 |
| Carr, DT; Hansen, HH; Sealy, R; Selawry, OS; Simon, R; Tucker, RD; van Wyk, CE | 1 |
| Chahinian, AP; Holland, JF; Jaffrey, IS; Mandel, EM; Teirstein, AS | 1 |
| Bedwinek, J; Goldberg, RS; Joss, RA; Krakoff, IH; Yates, JW | 1 |
| Guthrie, D; Way, S | 1 |
| Herson, J; Perez, C; Sutow, WW; Wang, YM | 1 |
| Carlson, M; Karakousis, CP | 1 |
| Banfi, A; Bonadonna, G; Rossi, A; Valagussa, P; Veronesi, U | 1 |
| Bonadonna, G; Rossi, A; Valagussa, P; Veronesi, U | 1 |
| Ensminger, WD; Frei, E; Glode, LM; Papathanasopoulos, N; Pitman, SW; Rosowsky, A | 1 |
| Kotz, R; Krisch, K; Mutz, I; Urban, C | 1 |
| Bechara, GH; Leme, JG; Sudo, LS | 1 |
| Costanzi, J; Hoogstraten, B; Kennedy, A; Maloney, TR; Palmer, RL; Rivkin, S; Samal, B; Smith, F; Thigpen, T; Tranum, B; Tucker, WG; Vaughn, CB; Wilson, H | 1 |
| Garcia Leme, J; Ramos de Oliveira, JC; Sudo, LS; Veríssimo de Mello, SB | 1 |
| Hayward, JL; Knight, RK; Rubens, RD | 1 |
| Edmonson, J; Holland, J; Kazam, E; Krant, M; Olson, K; Schneiderman, M; Scotto, J; Selawry, O; Shnider, B; Taylor, S | 1 |
| Levý, J; Valenta, J | 1 |
| Bonnet, JD; Braine, H; Costanzi, JJ; George, SL; Hoogstraten, B; Rivkin, SE; Samal, B; Thigpen, T | 1 |
| Bechara, GH; Dos Santos, RR; Leme, JG | 1 |
| Brincker, H | 1 |
| Mandel, MA | 1 |
| Akaza, H; Aso, Y | 1 |
| Arnold, H; Bross, K; Heidemann, E; Heim, ME; Hoffman, I; Josten, K; Manegold, C; Reinold, HM; Schalk, KP; Steinke, B | 1 |
| Amrein, PC; Fabian, RL | 1 |
| Kouri, MO; Pyrhönen, SO | 1 |
| Fosså, SD; Harland, SJ; Kaye, SB; Parmar, MK; Raghavan, D; Russell, JM; Uscinska, BM; Wood, R | 1 |
| Blomqvist, CP; Muhonen, TT; Pyrhönen, SO; Wiklund, TA | 1 |
| Alarcón, GS; Brooks, RH; Clegg, DO; Reading, JC; Singer, JZ; Skosey, JL; Ward, JR; Weisman, MH; Williams, HJ; Willkens, RF | 1 |
| Boyages, J; Driessen, C; Langlands, AO; Lindeman, GJ | 1 |
| Airoma, G; Bianco, AR; Contegiacomo, A; De Placido, S; Ferrante, G; Gentile, M; Gridelli, C; Lauria, R; Perrone, F | 1 |
| Amadori, S; Gherlinzoni, F; Guglielmi, C; Mandelli, F; Mazza, P; Tura, S | 1 |
| Davies, J; Habeshaw, T; Junor, E; Kaye, S; Paul, J; Rankin, E; Reed, N; Symonds, RP | 1 |
| Igawa, M; Kadena, H; Ohkuchi, T; Ueda, M; Usui, T | 1 |
| Anderson, H; Dougal, M; Kamthan, AG; Ostick, DG; Ranson, M; Russell, SA; Scarffe, JH; Wilkinson, MJ | 1 |
| Kaplan, MM; Knox, TA | 1 |
| Hall, RR; Macneil, HF; Neal, DE; Roberts, JT | 1 |
| Barlow, JF; Cullinan, S; Foley, JF; Kardinal, CG; Krook, JE; Moertel, CG; Norris, BD; Schutt, AJ; Tschetter, LK; Wieand, HS | 1 |
| Hill, BT; Price, LA | 1 |
| Affronti, ML; Coniglio, D; Gockerman, J; Halperin, E; Hart, L; Iglehart, JD; Jones, RB; Moore, J; Shogan, J; Shpall, EJ | 1 |
| Bruunshuus, I; Schmiegelow, K | 1 |
| Arakawa, S; Gohji, K; Gotoh, A; Hamami, G; Hara, I; Itani, A; Kamidono, S; Matsumoto, O; Ogawa, T; Takenaka, A | 1 |
| Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC | 1 |
| Clavel, M; Cognetti, F; Cortes-Funes, H; Dalesio, O; Dodion, P; Gignoux, B; Rossi, A; Rosso, R; Van Rymenant, M; Wildiers, J | 1 |
| Fujii, A; Ito, N; Iwamoto, T; Izumi, T; Miyasaki, Z; Morishita, S; Nagata, H; Nakamura, I; Ohshima, H; Oka, Y | 1 |
| Bechara, GH; Engrácia-de-Moraes, JR | 1 |
| Ouyang, PC | 1 |
| Akazawa, S; Ibayashi, J; Ishikawa, M; Matsuoka, T; Ogoshi, K; Ota, K; Sakai, Y; Sakata, Y; Sasaki, T; Wakui, A | 1 |
| Igawa, M; Ishino, T; Kume, T; Masu, C; Nakatsu, H; Ohnishi, Y; Okada, K; Ueda, M; Ueki, T; Usui, T | 1 |
| Hattori, T; Jinushi, K; Kim, R; Niimoto, M; Saeki, K; Saeki, T; Toi, M; Yanagawa, E; Yoshinaka, K | 1 |
| Luthra, HS | 1 |
| Clements, PJ; Davis, J | 1 |
| Anderson, N; Beauchamp, K; Bern, M; Lokich, J; Moore, C; Wallach, S; Williams, D | 1 |
| Barber, PV; Carroll, KB; Feinmann, D; James, RD; Lawson, BA; Steward, WP; Thatcher, N | 1 |
| Choo, YC; Ma, HK; Wong, LC | 1 |
| Bader, J; Bagley, CS; Danforth, DN; Lippman, ME; Sorace, RA; Steinberg, SM; Swain, SM; Wesley, MN | 1 |
| Costanzo-Nordin, MR; Grusk, BB; O'Connell, JB; Pifarre, R; Robinson, JA; Silver, MA; Sobotka, PA | 1 |
| Bruckner, H; Petrelli, NJ; Rustum, YM; Stablein, D | 1 |
| Akimoto, M; Iwasaki, H; Kasai, M; Kimura, M; Matano, S; Nakajima, Y; Sawano, A | 1 |
| Bonadonna, G; Buzzoni, R; Moliterni, A; Valagussa, P; Weiss, RB; Zambetti, M | 1 |
| Anderson, J; Bloomfield, CD; Cooper, MR; Ginsberg, SJ; Gottlieb, AJ; Hurd, DD; Lachant, NA | 1 |
| Kremer, JM; Lee, JK | 1 |
| Biron, P; Bouffet, E; Brunat-Mentigny, M; Frappaz, D; Kassir, A; Latour, JF; Philip, T | 1 |
| Damas, J; Deflandre, E; Remacle-Volon, G | 1 |
| Coleman, CN; Horning, SJ; Jacobs, C; Lewis, BJ; Rosenberg, SA; Tseng, A | 1 |
| Acton, RT; Alarcón, GS; Barger, BO; Gispen, JG; Johnson, JJ; Koopman, WJ | 1 |
| Brussaard, HE; de Wit, RF; van Eijk, CL; van Seters, WA; van Toorn, DW | 1 |
| Bowen, D; Bui, QQ; Robbins, TJ; Tran, MT | 1 |
| Bonadonna, G; Brambilla, C; Rossi, A; Tancini, G; Valagussa, P; Veronesi, U; Zambetti, M | 1 |
| Djerassi, I; Reggev, A | 1 |
| Case, D; Cooper, MR; Muss, HB; Nelson, EC; Pope, E; Puckett, JB; Resnick, MI; Richards, F; Spurr, CL; Zekan, P | 1 |
| Anteghini, HJ; Garcia-Leme, J; Sannomiya, P; Vianna, ES | 1 |
| Dold, U | 1 |
| Karrer, K; Pridun, N; Zwintz, E | 1 |
| Alberto, P; Broquet, MA; Jacot-Descombe, E; Montandon, A | 1 |
| Cardozo, EL | 1 |
| Vahrson, H | 1 |
| Bertino, JR; Capizzi, RL; DeConti, RC; Marsh, JC | 1 |
| Hansen, HH; Holland, JF; McCall, CB; Selawry, OS | 1 |
| Bertino, JR; DeConti, RC; Kaplan, SR; Mitchell, MS; Papac, R; Wawro, NW | 1 |
| Bennett, JM; Carbone, PP; Foley, HT | 1 |
| Amiel, JL; Clarysse, A; Hayat, M; Mathé, G; Schneider, M; Schwarzenberg, L | 1 |
| Bilder, J; Hornová, J | 1 |
| Landolt, AM | 1 |
| Bloom, HJ; Freeman, JE; Hall, RR; Nawrocki, A; Wallace, DM | 1 |
| Bernard, J; Blom, J; Boiron, M; Brunner, K; Cooper, MR; Cuttner, J; Ellison, RR; Gailani, S; Glidewell, OJ; Haurani, F; Holland, JF; Hoogstraten, B; Jacquillat, C; Levy, R; Lowenstein, L; Nissen, NI; Rege, VB; Serpick, AA; Silver, RT; Wasserman, L; Weil, M; Wiernik, PH | 1 |
| Simone, J | 1 |
| Blom, J; Stutz, FH; Tormey, DC | 1 |
| Cebrian Bonesana, A; De Macchi, GH; Eppinger-Helft, M; Hidalgo, G; Pavlovsky, A; Pavlovsky, S; Peñalver, JA; Sackmann Muriel, F | 1 |
| Andrews, R; Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Schwartz, RS; Skinner, MD | 1 |
| Cohen, SM; Greenspan, EM; Weiner, MJ | 1 |
| Priestman, TJ | 1 |
| Gerner, RE; Moore, GE | 1 |
| Damascelli, B; De Palo, GM; Di Pietro, S; Gennari, L; Molinari, R | 1 |
| Akao, T; Fujimoto, S; Ito, B; Miyoshi, T; Nomura, Y | 1 |
| Bluestone, R; Bohan, A; Goldberg, LS; Metzger, AL; Pearson, CM | 1 |
| Ansfield, FJ; Davis, HL; Ellerby, RA; Ramirez, G | 1 |
| Hoehn, RJ; Immons, RL; Ozerkis, AJ | 1 |
| Dano, K; Nissen, NI | 1 |
| Curran, RE; Johnson, RE; Senyszyn, JJ | 1 |
| Block, JB; Carbone, PP; Haskell, CM; Leventhal, BG; Selawry, OS | 1 |
| Ansfield, FJ; Carter, AC; Goldenberg, IS; Segaloff, A | 1 |
| Hoffman, J; Post, J | 1 |
| Weiss, AJ; Wilson, WL | 1 |
| Lee, SL; Rosner, F | 1 |
| Adachi, M; Enomoto, K; Fujimoto, S; Itoh, K; Watanabe, Y | 1 |
| Rollier, MR | 1 |
| Al-Sarraf, M; Sardesai, S; Vaitkevicius, VK; Wong, P | 1 |
| Bourgeois-Spinasse, J; Grupper, C | 1 |
| Herrick, RB; Sherman, M | 1 |
| Buschmann, H; Thein, P | 1 |
| Frost, P; Weinstein, GD | 1 |
| Denck, H; Karrer, K | 1 |
| Dawson, AA; Ogston, D; Philip, JF | 1 |
| Schewach-Millet, M; Ziprkowski, L | 1 |
| Curtis, GH; Fowler-Bergfeld, W; Roenigk, HH | 1 |
| Fernbach, DJ; Griffith, KM; Haddy, TB; Sullivan, MP; Vietti, TJ; Watkins, WL | 1 |
| Fry, L | 1 |
| Perry, S; Schwartz, SA | 1 |
| Jubin, E | 1 |
9 review(s) available for methotrexate and Leukopenia
| Article | Year |
|---|---|
Cytopenias among patients with rheumatic diseases using methotrexate: a meta-analysis of randomized controlled clinical trials.
Topics: Anemia; Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid; Humans; Leucovorin; Leukopenia; Methotrexate; Neutropenia; Pancytopenia; Randomized Controlled Trials as Topic; Rheumatic Diseases; Severity of Illness Index; Thrombocytopenia; Vitamin B Complex | 2020 |
The efficacy and safety comparison of first-line chemotherapeutic agents (high-dose methotrexate, doxorubicin, cisplatin, and ifosfamide) for osteosarcoma: a network meta-analysis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Humans; Ifosfamide; Leukopenia; Methotrexate; Network Meta-Analysis; Osteosarcoma; Survival Rate; Thrombocytopenia; Treatment Outcome | 2020 |
Baseline laboratory test abnormalities are common in early arthritis but rarely contraindicate methotrexate: study of three cohorts (ESPOIR, VErA, and Brittany).
Topics: Alanine Transaminase; Anemia; Antirheumatic Agents; Arthritis; Aspartate Aminotransferases; Cohort Studies; Contraindications; Diagnostic Tests, Routine; Early Diagnosis; Female; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Male; Methotrexate; Renal Insufficiency; Systemic Inflammatory Response Syndrome; Thrombocytopenia | 2013 |
The limited efficacy of methotrexate, actinomycin D and cisplatin (MAP) for patients with advanced testicular cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cisplatin; Dactinomycin; Drug Administration Schedule; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Salvage Therapy; Testicular Neoplasms; Thrombocytopenia; Treatment Outcome | 2003 |
The effect of chemotherapeutic agents on wound healing.
Topics: Adrenal Cortex Hormones; Anemia; Animals; Antineoplastic Agents; Azathioprine; Collagen; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukopenia; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasms; Tensile Strength; Thiotepa; Time Factors; Wound Healing | 1981 |
[(Management of acute toxicity after high dose methotrexate therapy)].
Topics: Adolescent; Blood Transfusion; Brain; Dose-Response Relationship, Drug; Female; Fluid Therapy; Furosemide; Humans; Kidney; Leucovorin; Leukopenia; Methotrexate; Osteosarcoma | 1979 |
Cytotoxic drugs: their clinical application to the rheumatic diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Depression, Chemical; Dermatomyositis; Drug Evaluation; Female; Fertility; Gastrointestinal Diseases; Granulomatosis with Polyangiitis; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Myositis; Neoplasms; Polyarteritis Nodosa; Psoriasis; Pulmonary Fibrosis; Rheumatic Diseases | 1986 |
Immunosuppressive therapy of immunoinflammatory diseases.
Topics: Abnormalities, Multiple; Abortion, Spontaneous; Collagen Diseases; Cyclophosphamide; Female; Gastrointestinal Diseases; Hematologic Diseases; Immune System Diseases; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Leukopenia; Liver Function Tests; Lymphoma; Mercaptopurine; Methotrexate; Nervous System Diseases; Pregnancy | 1974 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
62 trial(s) available for methotrexate and Leukopenia
| Article | Year |
|---|---|
The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia.
Topics: Adolescent; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Dactinomycin; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukopenia; Menstrual Cycle; Methotrexate; Middle Aged; Nausea; Pregnancy; Retrospective Studies; Treatment Outcome; Uterine Neoplasms; Young Adult | 2020 |
Comparison of two dose escalation strategies of methotrexate in active rheumatoid arthritis: a multicentre, parallel group, randomised controlled trial.
Topics: Adolescent; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Polyglutamic Acid; Thrombocytopenia; Treatment Outcome; Young Adult | 2021 |
Efficacy and Toxicity of Metronomic Chemotherapy in Metastatic Breast Cancer: Egyptian Experience.
Topics: Administration, Metronomic; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Egypt; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leukopenia; Methotrexate; Middle Aged; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A | 2017 |
Mexican Childhood Acute Lymphoblastic Leukemia: A Pilot Study of the MDR1 and MTHFR Gene Polymorphisms and Their Associations with Clinical Outcomes.
Topics: Adolescent; ATP Binding Cassette Transporter, Subfamily B; Child; Child, Preschool; Female; Homozygote; Humans; Leukopenia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Mucositis; Pilot Projects; Polymorphism, Restriction Fragment Length; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors | 2016 |
High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Karnofsky Performance Status; Leukopenia; Lomustine; Longitudinal Studies; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Pilot Projects; Procarbazine; Proportional Hazards Models; Radiotherapy, Adjuvant; Survival Analysis; Thrombocytopenia; Time Factors; Treatment Outcome | 2009 |
[Efficacy of modified B-NHL-BFM-90 protocol on anaplastic T-cell lymphoma in children and adolescents].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; L-Lactate Dehydrogenase; Leukopenia; Lymphoma, Large-Cell, Anaplastic; Male; Methotrexate; Neoplasm Staging; Remission Induction; Stem Cell Transplantation; Thrombocytopenia; Vincristine; Vindesine | 2009 |
Cyclophosphamide, doxorubicin, vincristine, methotrexate, bleomicin and prednisone plus rituximab in untreated young patients with low-risk (age-adjusted international prognostic index 0-1) diffuse large B-cell lymphoma.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Italy; Leukopenia; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Retrospective Studies; Risk Factors; Rituximab; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2009 |
Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II).
Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm, Residual; Neutropenia; Paclitaxel; Receptors, Estrogen; Treatment Outcome | 2012 |
Pretreatment EBV-DNA copy number is predictive of response and toxicities to SMILE chemotherapy for extranodal NK/T-cell lymphoma, nasal type.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; DNA, Viral; Epstein-Barr Virus Infections; Etoposide; Female; Herpesvirus 4, Human; Humans; Ifosfamide; Kaplan-Meier Estimate; Leukopenia; Lymphoma, Extranodal NK-T-Cell; Male; Methotrexate; Middle Aged; Nasal Mucosa; Neutropenia; Prognosis; Prospective Studies; Steroids; Treatment Outcome; Young Adult | 2012 |
Outcome of elderly patients with primary CNS lymphoma in the G-PCNSL-SG-1 trial.
Topics: Age Factors; Aged; Antimetabolites; Central Nervous System Neoplasms; Combined Modality Therapy; Confidence Intervals; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Leukopenia; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Salvage Therapy; Survival Analysis; Watchful Waiting | 2012 |
[Clinical randomized comparative trial of ProMACE-CytaBOM regimen and CHOP regimen in treating non-Hodgkin's lymphoma].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Nausea; Prednisone; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine | 2005 |
Evaluation of toxicities induced by chemotherapy in breast cancer patients.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Breast Neoplasms; Cisplatin; Cohort Studies; Drug Evaluation; Drug Therapy, Combination; Erythrocyte Count; Erythrocytes; Female; Fluorouracil; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Leukocytes; Leukopenia; Methotrexate; Middle Aged; Pakistan; Platelet Count; Tamoxifen; Thrombocytopenia | 2005 |
Trastuzumab in combination with metronomic cyclophosphamide and methotrexate in patients with HER-2 positive metastatic breast cancer.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Administration Schedule; Female; Gene Amplification; Genes, erbB-2; Humans; Immunization, Passive; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Proteins; Neutropenia; Receptor, ErbB-2; Remission Induction; Trastuzumab; Treatment Outcome; Ventricular Dysfunction, Left | 2006 |
Analysis of efficacy and toxicity of chemotherapy with cisplatin, 5-fluorouracil, methotrexate and leucovorin (PFML) and radiotherapy in the treatment of locally advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Radiotherapy Dosage | 2007 |
Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis.
Topics: Administration, Oral; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; C-Reactive Protein; Cyclophosphamide; Drug Administration Schedule; Female; Glomerulonephritis; Granulomatosis with Polyangiitis; Hemoptysis; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Leukopenia; Male; Methotrexate; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Treatment Outcome | 2007 |
[Adjuvant chemotherapy with carminomycin and bleomycetin after radical surgery for squamous cell carcinoma of the lung (preliminary communication)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Carubicin; Clinical Trials as Topic; Daunorubicin; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Vomiting | 1982 |
Activity of sequential low-dose methotrexate and fluorouracil in advanced colorectal carcinoma: attempt at correlation with tissue and blood levels of phosphoribosylpyrophosphate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Lymphocytes; Male; Methotrexate; Middle Aged; Mucous Membrane; Nausea; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Prospective Studies; Rectal Neoplasms; Ribose-Phosphate Pyrophosphokinase; Thrombocytopenia; Vomiting | 1984 |
Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine; Vincristine | 1982 |
Comparison of chemotherapy alone versus chemotherapy and radiation therapy of extensive small cell carcinoma of the lung.
Topics: Aged; Body Weight; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Random Allocation; Thrombocytopenia | 1983 |
Combined modality treatment of extensive small cell lung cancer: a Southwest Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Carcinoma, Small Cell; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Etoposide; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Random Allocation; Stomatitis; Vincristine | 1984 |
Toxicity associated with combination chemotherapy for osteosarcoma: a report of the cooperative osteosarcoma study (COSS 80).
Topics: Acute Kidney Injury; Adolescent; Adult; Antineoplastic Agents; Body Weight; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Osteosarcoma | 1983 |
Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Trials as Topic; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Diseases; Neoplasm Recurrence, Local; Random Allocation | 1983 |
A comparison of intermittent vs. continuous and of adriamycin vs. methotrexate 5-drug chemotherapy for advanced breast cancer. A Cancer and Leukemia Group B study.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart Diseases; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Random Allocation; Time Factors; Vincristine | 1984 |
[A randomized trial of adriamycin, cyclophosphamide, ftorafur (ACF) and adriamycin, cyclophosphamide, ftorafur, methotrexate (ACFM) in patients with advanced breast cancer].
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Humans; Leukopenia; Methotrexate; Middle Aged; Nausea; Random Allocation; Tegafur; Thrombocytosis | 1984 |
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Thrombocytopenia; Vomiting | 1984 |
Chemotherapy drug dose alteration due to radiation therapy in an adjuvant situation in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged | 1984 |
Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma. A comparative trial of localized versus extensive radiotherapy including prophylactic brain irradiation in patients receiving combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Deglutition Disorders; Drug Therapy, Combination; Female; Hospitalization; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Radiotherapy; Thrombocytopenia | 1980 |
Sequential chemotherapy of advanced colorectal cancer with standard or high-dose methotrexate followed by 5-fluorouracil.
Topics: Aged; Clinical Trials as Topic; Colonic Neoplasms; Digestive System; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Rectal Neoplasms; Uremia | 1982 |
Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Fluorouracil; Follow-Up Studies; Humans; Italy; Leukopenia; Methotrexate; Middle Aged; Remission Induction; Survival Rate; Vinblastine; Vinorelbine | 1994 |
[Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy]
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Stomach Neoplasms | 1994 |
CVM versus ACE in the treatment of small cell lung cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carboplatin; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Infant, Newborn; Infections; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia; Treatment Outcome; Vinblastine | 1993 |
Phase II study of sequential high-dose methotrexate (MTX) and 5-fluorouracil (F) alternated with epirubicin (E) and cisplatin (P) [FEMTX-P] in advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Thrombocytopenia | 1993 |
A phase I trial of a modified, dose intensive FAMTX regimen (high dose 5-fluorouracil+doxorubicin+high dose methotrexate+leucovorin) with oral uridine rescue.
Topics: Administration, Oral; Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Neutropenia; Uridine | 1996 |
Toxicity and results of MVAC (methotrexate, vinblastine, adriamycin and cisplatin) chemotherapy in advanced urothelial carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Follow-Up Studies; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Urethral Neoplasms; Urinary Bladder Neoplasms; Vinblastine; Vomiting | 1997 |
Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Costs and Cost Analysis; Cyclophosphamide; Drug Therapy, Combination; Epirubicin; Female; Fever; Fluorouracil; Granulocyte Colony-Stimulating Factor; Humans; Length of Stay; Leukopenia; Methotrexate; Middle Aged; Neoplasm Metastasis; Netherlands; Prospective Studies; Recombinant Proteins | 1999 |
Leucocyte nadir as a marker for chemotherapy efficacy in node-positive breast cancer treated with adjuvant CMF.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Drug Monitoring; Female; Fluorouracil; Follow-Up Studies; Humans; Leukocyte Count; Leukopenia; Life Tables; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Receptors, Progesterone; Survival Rate; Time Factors | 1999 |
Adjuvant doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy in premenopausal women with axillary lymph node positive breast carcinoma.
Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Leukopenia; Lymph Nodes; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Premenopause; Survival Analysis; Time Factors; Treatment Outcome | 2000 |
Vinblastine, methotrexate, bleomycin, in the management of head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Head and Neck Neoplasms; Humans; Leukopenia; Methotrexate; Thrombocytopenia; Vinblastine | 1979 |
Combination chemotherapy of advanced lung cancer: a randomized trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukopenia; Lomustine; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Procarbazine; Thrombocytopenia; Vincristine | 1976 |
The CMF program for operable breast cancer with positive axillary nodes. Updated analysis on the disease-free interval, site of relapse and drug tolerance.
Topics: Amenorrhea; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Thrombocytopenia | 1977 |
Adjuvant combination chemotherapy in primary mammary carcinoma: the CMF program.
Topics: Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leukopenia; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Time Factors | 1977 |
A Phase 1 study of high doses of aminopterin with leucovorin rescue in patients with advanced metastatic tumors.
Topics: Aminopterin; Bone Marrow; Clinical Trials as Topic; Drug Administration Schedule; Humans; Kidney; Leucovorin; Leukopenia; Methotrexate; Neoplasm Metastasis; Neoplasms; Solubility | 1979 |
Chemotherapy of advanced breast cancer: a controlled randomized trial of cyclophosphamide versus a four-drug combination.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Vinblastine | 1975 |
Methotrexate compared with placebo in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Placebos; Stomatitis | 1977 |
Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study.
Topics: Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Heart; Humans; Leukopenia; Methotrexate; Prednisone; Vincristine; Vomiting | 1976 |
Cyclic alternating chemotherapy of high-grade malignant non-Hodgkin lymphomas with VIM-Bleo and CHOP.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Prospective Studies; Time Factors; Vincristine | 1992 |
Treatment of recurrent head and neck cancer with cisplatin and 5-fluorouracil vs. the same plus bleomycin and methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Ear, Middle; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Hypertension; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors | 1992 |
Phase II study of epirubicin sequential methotrexate and 5-fluorouracil for advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Diarrhea; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Rectal Neoplasms | 1992 |
Initial combination chemotherapy with cisplatin, methotrexate and vinblastine in locally advanced transitional cell carcinoma--response rate and pitfalls. MRC Subgroup in Advanced Bladder Cancer (on behalf of the MRC Urological Working Party).
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Kidney; Leukopenia; Male; Methotrexate; Middle Aged; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 1992 |
Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis. A controlled clinical trial.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Auranofin; Double-Blind Method; Drug Therapy, Combination; Humans; Leukopenia; Methotrexate; Middle Aged; Thrombocytopenia | 1992 |
Phase III comparative trial (m-BACOD v m-BNCOD) in the treatment of stage II to IV non-Hodgkin's lymphomas with intermediate- or high-grade histology.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leucovorin; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mitoxantrone; Mouth Mucosa; Neoplasm Staging; Neutropenia; Recurrence; Remission Induction; Stomatitis; Stroke Volume; Survival Rate; Vincristine | 1990 |
A phase III trial on the therapy of advanced pancreatic carcinoma. Evaluations of the Mallinson regimen and combined 5-fluorouracil, doxorubicin, and cisplatin.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thrombocytopenia; Vincristine | 1990 |
Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Random Allocation; Vincristine; Vomiting | 1987 |
[Randomized multicenter trial of sequential methotrexate and 5-fluorouracil versus 5-fluorouracil alone in advanced gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Administration Schedule; Female; Fluorouracil; Humans; Japan; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Nausea; Prospective Studies; Quality of Life; Random Allocation; Remission Induction; Stomach Neoplasms; Vomiting | 1989 |
[M-VAC (methotrexate, vinblastine, adriamycin and cisplatin) chemotherapy in advanced renal pelvic and ureteral carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Evaluation; Female; Humans; Japan; Kidney Neoplasms; Kidney Pelvis; Leukopenia; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Remission Induction; Thrombocytopenia; Ureteral Neoplasms; Vinblastine | 1989 |
The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colorectal Neoplasms; Diarrhea; Fluorouracil; Humans; Leucovorin; Leukopenia; Methotrexate; Random Allocation; Thrombocytopenia | 1988 |
Adjuvant chemotherapy after conservative surgery plus irradiation versus modified radical mastectomy. Analysis of drug dosing and toxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Methotrexate; Radiotherapy, High-Energy; Random Allocation | 1987 |
A long-term prospective study of the use of methotrexate in rheumatoid arthritis. Update after a mean of fifty-three months.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Central Nervous System Diseases; Clinical Trials as Topic; Gastrointestinal Diseases; HLA Antigens; Humans; Leukopenia; Methotrexate; Middle Aged; Mouth; Pain; Phenotype; Prospective Studies; Time Factors | 1988 |
Acute lymphocytic leukemia in children: maintenance therapy with methotrexat administered intermittently. Acute Leukemia Group B.
Topics: Adolescent; Adult; Blood Platelets; Bone Marrow Cells; Bone Marrow Examination; Child; Child, Preschool; Dyspnea; Female; Gastrointestinal Diseases; Hemoglobins; Herpesviridae Infections; Humans; Infant; Infant, Newborn; Infections; Injections, Intramuscular; Leukemia, Lymphoid; Leukocyte Count; Leukopenia; Male; Methotrexate; Mouth Diseases; Neurologic Manifestations; Osteoporosis; Pneumonia; Pneumonia, Pneumocystis; Prednisolone; Respiratory Tract Diseases; Thrombocytopenia; Vincristine | 1969 |
Acute lymphocytic leukemia in childhood.
Topics: Asparaginase; Black People; Bone Marrow Examination; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunosuppression Therapy; Infections; Injections, Spinal; Leukemia, Lymphoid; Leukopenia; Male; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1974 |
Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma.
Topics: Adenocarcinoma; Alopecia; Antineoplastic Agents; Autopsy; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Dactinomycin; Diarrhea; Evaluation Studies as Topic; Humans; Leukopenia; Lung Abscess; Methotrexate; Nitrosourea Compounds; Paresthesia; Radiotherapy; Sepsis; Stomatitis; Thrombocytopenia; Vincristine | 1972 |
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Radiography; Sarcoma, Ewing; Stomatitis; Suppuration; Thrombocytopenia; Vomiting | 1970 |
167 other study(ies) available for methotrexate and Leukopenia
| Article | Year |
|---|---|
Nomogram predicting leukopenia in osteosarcoma after high-dose methotrexate chemotherapy.
Topics: Bone Neoplasms; Female; Humans; Ki-67 Antigen; Leukopenia; Methotrexate; Nomograms; Osteosarcoma | 2022 |
Safety of trimethoprim-sulfamethoxazole for Pneumocystis jirovecii pneumonia prophylaxis in patients taking methotrexate.
Topics: Adult; Autoimmune Diseases; Contraindications, Drug; Drug Therapy, Combination; Female; Humans; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Pneumonia, Pneumocystis; Transaminases; Trimethoprim, Sulfamethoxazole Drug Combination | 2021 |
Ambulatory High-dose Methotrexate Administration in Pediatric Osteosarcoma Patients at a Single Institution in Argentina.
Topics: Adolescent; Algorithms; Ambulatory Care; Anemia; Antacids; Argentina; Chemical and Drug Induced Liver Injury; Child; Diarrhea; Female; Humans; Hydrogen-Ion Concentration; Leucovorin; Leukopenia; Male; Methotrexate; Mucositis; Neutropenia; Osteosarcoma; Retrospective Studies; Thrombocytopenia; Vomiting | 2017 |
Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heterozygote; Humans; Leukopenia; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Methyltransferases; Myelopoiesis; Nucleic Acid Synthesis Inhibitors; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk; Scandinavian and Nordic Countries; Survival Analysis | 2015 |
Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Aging; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Child; Child, Preschool; Female; Genotype; Humans; Leukocyte Count; Leukopenia; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; PTEN Phosphohydrolase; Risk Assessment | 2016 |
Sarcoidal anemia and leukopenia treated with methotrexate and mycophenolate mofetil.
Topics: Adult; Anemia; Bone Marrow Diseases; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Leukopenia; Male; Methotrexate; Mycophenolic Acid; Sarcoidosis; Skin Diseases | 2009 |
A single-center experience with methotrexate after thiopurine therapy in pediatric Crohn disease.
Topics: Antibodies, Monoclonal; Child; Crohn Disease; Drug Tolerance; Female; Humans; Infliximab; Leukopenia; Male; Mercaptopurine; Methotrexate; Methyltransferases; Nausea; Outcome Assessment, Health Care; Patient Compliance; Remission Induction; Retrospective Studies; Transaminases | 2010 |
[Risk factors and subjective symptoms of drug-induced leucopenia].
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Autoimmune Diseases; Case-Control Studies; Child; Databases, Factual; Female; Humans; Kidney Diseases; Leukopenia; Logistic Models; Male; Methimazole; Methotrexate; Middle Aged; Risk Factors; Ritodrine; Sex Factors; Ticlopidine; Young Adult | 2011 |
Adverse effects of low dose methotrexate in rheumatoid arthritis patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Age Distribution; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Blood Chemical Analysis; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Pancytopenia; Prognosis; Risk Assessment; ROC Curve; Severity of Illness Index; Sex Distribution; Thrombocytopenia; Young Adult | 2012 |
High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.
Topics: Alleles; Antimetabolites, Antineoplastic; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genetic Carrier Screening; Genotype; Homozygote; Humans; Leukopenia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Treatment Outcome | 2012 |
Association between polymorphisms of dihydrofolate reductase and gamma glutamyl hydrolase genes and toxicity of high dose methotrexate in children with acute lymphoblastic leukemia.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Female; gamma-Glutamyl Hydrolase; Gene Frequency; Genotype; Humans; Infant; Leukopenia; Male; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase; Thrombocytopenia | 2012 |
Myelosuppression monitoring after immunomodulator initiation in veterans with inflammatory bowel disease: a national practice audit.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Azathioprine; Delivery of Health Care; Drug Monitoring; Drug Prescriptions; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Leukocyte Count; Leukopenia; Male; Medical Audit; Mercaptopurine; Methotrexate; Middle Aged; Practice Guidelines as Topic; Treatment Outcome; United States; United States Department of Veterans Affairs; Veterans | 2012 |
Methotrexate rescue therapy in lung transplantation.
Topics: Adult; Child; Female; Humans; Immunosuppressive Agents; Leukopenia; Lung Transplantation; Male; Methotrexate; Middle Aged; Treatment Outcome | 2002 |
IMMUNOSUPPRESSIVE DRUG THERAPY IN CANINE RENAL AND SKIN HOMOGRAFTS.
Topics: Allergy and Immunology; Allografts; Animals; Azaserine; Dactinomycin; Dogs; Immunosuppressive Agents; Kidney Transplantation; Leukopenia; Methotrexate; Purines; Pyrazoles; Pyrimidines; Research; Skin Transplantation; Thrombocytopenia; Urea | 1963 |
SYSTEMIC THERAPY WITH AMETHOPTERIN IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.
Topics: Bone Marrow Examination; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Humans; Injections, Intravenous; Laryngeal Neoplasms; Leukopenia; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Stomatitis; Tongue Neoplasms; Tonsillar Neoplasms; Toxicology | 1963 |
METHOTREXATE-INDUCED HEPATIC INJURY IN AN ADULT. A CASE REPORT.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Child; Hepatitis; Humans; Leukemia; Leukopenia; Methotrexate; Pathology; Psoriasis; Toxicology | 1964 |
METHOTREXATE THERAPY IN PSORIATIC ARTHRITIS; DOUBLE-BLIND STUDY ON 21 PATIENTS.
Topics: Alopecia; Arthritis; Arthritis, Psoriatic; Biomedical Research; Double-Blind Method; Drug Eruptions; Drug Therapy; Gastrointestinal Tract; Leukopenia; Liver Diseases; Methotrexate; Psoriasis; Skin; Toxicology; Triamcinolone | 1964 |
TREATMENT OF CANCER OF THE HEAD AND NECK BY CHEMOTHERAPY.
Topics: Alopecia; Diarrhea; Erythema; Head; Head and Neck Neoplasms; Injections, Intra-Arterial; Leukopenia; Mechlorethamine; Methotrexate; Mucous Membrane; Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Ulcer; Urticaria | 1964 |
PARENTERAL VS. ORAL FOLIC ACID ANTAGONISTS.
Topics: Alanine Transaminase; Aminopterin; Arthritis; Blood Platelets; Drug Therapy; Erythema; Folic Acid Antagonists; Humans; Kidney Function Tests; Leukocyte Count; Leukopenia; Liver Function Tests; Methotrexate; Nausea; Psoriasis; Toxicology | 1964 |
THERAPEUTIC PROGRESS IN DERMATOLOGY.
Topics: Choline; Dermatology; Drug Therapy; Humans; Leukopenia; Methotrexate; Pharmacology; Psoriasis; Urticaria | 1965 |
FOLIC-ACID ANTAGONISTS IN TREATMENT OF PSORIASIS.
Topics: Drug Therapy; Duodenal Ulcer; Folic Acid Antagonists; Kidney Diseases; Kidney Tubules; Leukopenia; Melena; Methotrexate; Mouth Diseases; Necrosis; Pathology; Psoriasis; Toxicology | 1965 |
Translocation model of Candida albicans in DBA-2/J mice with protein calorie malnutrition mimics hematogenous candidiasis in humans.
Topics: Animals; Candida albicans; Candidiasis; Cyclophosphamide; Disease Models, Animal; Feces; Female; Fungemia; Humans; Immunosuppressive Agents; Intestinal Mucosa; Intestines; Leukopenia; Liver; Methotrexate; Mice; Mice, Inbred DBA; Protein-Energy Malnutrition; Specific Pathogen-Free Organisms | 2003 |
[Efficacy and side effects of methotrexate in the treatment of ectopic pregnancy].
Topics: Abdominal Pain; Abortifacient Agents, Nonsteroidal; Adult; Alanine Transaminase; Dose-Response Relationship, Drug; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Leukopenia; Methotrexate; Mouth Diseases; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Treatment Outcome; Vomiting | 2003 |
Combined intravenous methotrexate and cyclophosphamide for refractory childhood lupus nephritis.
Topics: Blood Proteins; Chronic Disease; Complement C3; Creatinine; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Leukopenia; Lupus Nephritis; Methotrexate; Prednisone; Serum Albumin | 2004 |
Urinary tract infections and lupus erythematosus.
Topics: Adult; Age Factors; Antibodies, Antinuclear; Antirheumatic Agents; Escherichia coli; Female; Hospitalization; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Prevalence; Prospective Studies; Recurrence; Risk Factors; Thrombocytopenia; Urinary Tract Infections | 2004 |
Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cranial Irradiation; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Pneumonia; Prednisone; Procarbazine; Retrospective Studies; Sepsis; Vincristine | 2005 |
[Etopside, methotrexate, kengshengmycin/etopside, cisplatin chemotherapy for chemorefractory gestational trophoblastic tumour].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Dactinomycin; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Gestational Trophoblastic Disease; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Staging; Pregnancy; Treatment Outcome; Trophoblastic Tumor, Placental Site; Uterine Neoplasms | 2005 |
Clinical problem-solving. Lost in transcription.
Topics: Bone Marrow; Diagnosis, Differential; Female; Fever; Hematuria; Humans; Immunosuppressive Agents; Leukopenia; Medical Records Systems, Computerized; Medication Errors; Methotrexate; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Thrombocytopenia; Urinary Catheterization; Urination Disorders | 2006 |
Adverse events of MVAC chemotherapy in patients with advanced urothelial cancer of the bladder.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neutropenia; Retrospective Studies; Serotonin Antagonists; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 2007 |
Association analysis of glutathione-S-transferase P1 (GSTP1) polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Humans; Inactivation, Metabolic; Leukopenia; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Urologic Neoplasms; Urothelium; Vinblastine | 2007 |
Clinical evaluation of two combination chemotherapies for the treatment of small cell carcinoma of the lung.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nimustine; Nitrosourea Compounds; Pulmonary Fibrosis; Thrombocytopenia; Vincristine | 1984 |
Optimal schedule of methotrexate and 5-fluorouracil in human breast cancer.
Topics: Breast Neoplasms; Cell Line; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Drug Synergism; Female; Fluorouracil; Humans; Hypoxanthines; Leucovorin; Leukopenia; Methotrexate; Nausea; Phosphoribosyl Pyrophosphate; Time Factors | 1982 |
Continuous infusion vincristine and bleomycin with high dose methotrexate for resistant non-Hodgkin's lymphoma.
Topics: Adult; Aged; Bleomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Infusions, Parenteral; Leucovorin; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Stomatitis; Time Factors; Vincristine | 1982 |
Acute bleomycin and methotrexate toxicity: report of two cases.
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Gingivitis, Necrotizing Ulcerative; Humans; Hypotension; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Thrombocytopenia | 1982 |
Hydroxyurea fails to improve the results of MBD chemotherapy in cancer of the head and neck, but reduces toxicity.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Hydroxyurea; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia | 1983 |
Phase-II study of cis-diammine-dichloro platinum (cis-platinum), bleomycin and methotrexate for advanced squamous cell carcinoma of head and neck.
Topics: Adolescent; Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Child; Child, Preschool; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Leukopenia; Male; Methotrexate; Middle Aged | 1984 |
Evaluation of combined cyclophosphamide and methotrexate therapy in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Cyclophosphamide; Drug Evaluation; Female; Humans; Hydroxyindoleacetic Acid; Leukopenia; Male; Malignant Carcinoid Syndrome; Methotrexate; Middle Aged; Neoplasm Metastasis | 1984 |
High-dose methotrexate in small cell lung cancer. Lack of efficacy in preventing CNS relapse.
Topics: Aged; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Nervous System Neoplasms; Paraneoplastic Syndromes; Smoking; Thrombocytopenia | 1983 |
Sequential methotrexate and 5-fluorouracil: improved response rate in metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Drug Eruptions; Drug Evaluation; Drug Synergism; Female; Fluorouracil; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Rectal Neoplasms | 1984 |
Treatment of metastatic colorectal carcinoma with 5-FU, mitomycin, vincristine, and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Rectal Neoplasms; Thrombocytopenia; Vincristine | 1984 |
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mitolactol; Mitomycins; Nausea; Prednisone; Soft Tissue Neoplasms; Thrombocytopenia; Time Factors; Vincristine; Vomiting | 1984 |
Evaluation of the LSA2L2 protocol for treatment of childhood non-Hodgkin's lymphoma. A report from the Polish Children's Leukemia/Lymphoma Study Group.
Topics: Abdominal Neoplasms; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Staging; Prednisone; Prognosis; Vincristine | 1984 |
Diffuse aggressive lymphomas: increased survival after alternating flexible sequences of proMACE and MOPP chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Humans; Leucovorin; Leukopenia; Lymphoma; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Vincristine | 1983 |
[Chemotherapy of metastasizing breast cancer. Adriamycin mono and combination therapy after LMFP pretreatment].
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Thrombocytopenia; Vincristine | 1983 |
Chemotherapy for metastatic transitional carcinoma of the urinary tract. A prospective trial of methotrexate, adriamycin, and cyclophosphamide (MAC) with cis-platinum for failure.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Inflammation; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane; Prospective Studies; Thrombocytopenia; Urologic Neoplasms | 1983 |
Cis-platinum plus high-dose methotrexate. Toxicity and efficacy in ovarian carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Cisplatin; Cystadenocarcinoma; Drug Therapy, Combination; Female; Humans; Kidney; Leukopenia; Methotrexate; Middle Aged; Ovarian Neoplasms; Stomatitis | 1983 |
Adjuvant chemotherapy (CMF) for breast carcinoma. Patient's compliance and total dose achieved.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Menopause; Methotrexate; Middle Aged; Patient Compliance | 1983 |
The treatment of histiocytic lymphoma.
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leucovorin; Leukopenia; Lymphoma, Large B-Cell, Diffuse; Methotrexate; Prednisone; Procarbazine; Radiotherapy, High-Energy; Thrombocytopenia; Vincristine | 1980 |
Clinical pharmacology of methotrexate.
Topics: Animals; Creatinine; Half-Life; Haplorhini; Humans; Intestinal Absorption; Kidney; Leukopenia; Liver; Methotrexate; Rats; Thrombocytopenia; Tissue Distribution | 1981 |
[The use of lithium carbonate in mastectomized patients undergoing cancer therapy].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Lithium; Lithium Carbonate; Mastectomy; Methotrexate; Middle Aged; Postoperative Care; Postoperative Complications | 1982 |
Adjuvant chemotherapy (CMF) for breast carcinoma: hematological side effects.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Methotrexate; Nausea; Neoplasm Staging; Platelet Count; Time Factors; Vomiting | 1982 |
VP-16 and adriamycin in patients with advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prednisone; Thrombocytopenia; Vincristine; Vomiting | 1982 |
Pneumonia during therapy for childhood acute lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Leukemia, Lymphoid; Leukopenia; Methotrexate; Pneumonia; Pneumonia, Pneumocystis; Surveys and Questionnaires; Time Factors | 1980 |
Moderate-dose methotrexate in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diarrhea; Female; Head and Neck Neoplasms; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mucous Membrane | 1981 |
High-dose methotrexate with citrovorum factor and vincristine in the treatment of malignant mesothelioma.
Topics: Adult; Aged; Asbestos; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukopenia; Male; Mesothelioma; Methotrexate; Middle Aged; Peritoneal Neoplasms; Pleural Neoplasms; Time Factors; Vincristine | 1982 |
Lethal side effects of high dose methotrexate therapy.
Topics: Acute Kidney Injury; Adult; Female; Humans; Leukopenia; Lung Neoplasms; Lymphoma; Male; Methotrexate; Middle Aged | 1982 |
Endotoxin-induced pulmonary vascular injury is mainly mediated by activated neutrophils in rats.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Anticoagulants; Antithrombin III; Capillary Permeability; Dansyl Compounds; Endotoxins; Factor Xa; Fibrin Fibrinogen Degradation Products; Glycine; Heparin; Injections, Intravenous; Leukocyte Elastase; Leukopenia; Lipopolysaccharides; Lung; Male; Methotrexate; Molecular Sequence Data; Neutrophils; Pancreatic Elastase; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Wistar; Shock, Septic; Specific Pathogen-Free Organisms; Sulfonamides | 1995 |
CD4+ T cell-mediated leukopenia of Felty's syndrome successfully treated with granulocyte-colony-stimulating factor and methotrexate.
Topics: CD4 Antigens; Felty Syndrome; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Methotrexate; Middle Aged; T-Lymphocytes | 1994 |
M-VEC (methotrexate, vinblastine, 4'-epirubicin and cisplatin) combined with glycosylated recombinant human granulocyte colony-stimulating factor (rhG-CSF) for the treatment of transitional cell carcinoma of urothelium: reduction in toxicity produced by r
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Epirubicin; Female; Glycosylation; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Recombinant Proteins; Survival Analysis; Thrombocytopenia; Urinary Bladder Neoplasms; Vinblastine | 1994 |
[Optimal way of administration of granulocyte colony stimulating factor in the treatment of urological cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Administration Schedule; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Testicular Neoplasms; Ureteral Neoplasms; Urinary Bladder Neoplasms; Vinblastine | 1993 |
[Effect of recombinant human granulocyte colony stimulating factor in patients with transitional cell carcinoma of the urothelium receiving methotrexate, etoposide and cisplatinum combination chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Recombinant Proteins; Urologic Neoplasms; Vinblastine | 1993 |
[Appropriate administration of granulocyte colony stimulating factor for malignant lymphoma of the head and neck].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Head and Neck Neoplasms; Humans; Leukopenia; Lymphoma; Methotrexate; Prednisone; Teniposide; Vincristine | 1993 |
Edematogenic responses induced by Bothrops jararaca venom in rats: role of lymphocytes.
Topics: Analysis of Variance; Animals; Bothrops; Crotalid Venoms; Drug Interactions; Edema; Leukocyte Count; Leukopenia; Ligation; Lymphocyte Transfusion; Lymphocytes; Lymphopenia; Male; Methotrexate; Neutrophils; Rats; Rats, Wistar; Thoracic Duct | 1994 |
Adverse effects of low dose methotrexate therapy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Humans; Leukopenia; Linear Models; Male; Methotrexate; Middle Aged; Pneumonia; Predictive Value of Tests; Prevalence; Retrospective Studies; Risk Factors; Time Factors | 1993 |
Myelodysplastic syndromes and acute myeloid leukemia in connective tissue disease after single-agent chemotherapy.
Topics: Acute Disease; Adult; Aged; Antigens, CD; Antirheumatic Agents; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Cytogenetics; Female; Humans; Leukemia, Myeloid; Leukopenia; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes | 1996 |
The leucocyte nadir, a predictor of chemotherapy efficacy?
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Monitoring; Female; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Methotrexate; Neoplasms; Predictive Value of Tests | 1999 |
[Evaluation of the CCNU-COP regimen for primary refractory and recurrent non-Hodgkin's lymphoma].
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Hydrocortisone; Leukopenia; Lomustine; Lymphoma, Non-Hodgkin; Male; Methotrexate; Methylprednisolone; Middle Aged; Treatment Outcome; Vincristine | 1999 |
Methotrexate and corticosteroid therapy for pediatric localized scleroderma.
Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Child, Preschool; Confidence Intervals; Dermatologic Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Injections, Intravenous; Leukopenia; Male; Methotrexate; Methylprednisolone; Placebos; Recurrence; Remission Induction; Scleroderma, Localized | 2000 |
Effect of obesity on the leukocyte nadir in women treated with adjuvant cyclophosphamide, methotrexate, and fluorouracil dosed according to body surface area.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Constitution; Body Mass Index; Body Surface Area; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Obesity | 2001 |
[Study of neoadjuvant chemotherapy for invasive bladder cancer with MEC (methotrexate, epirubicin, cisplatin) therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Drug Administration Schedule; Epirubicin; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Prognosis; Survival Analysis; Thrombocytopenia; Urinary Bladder Neoplasms | 2001 |
[Cytopenia associated with low dose pulse methotrexate in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Pancytopenia; Pulse Therapy, Drug; Thrombocytopenia | 2001 |
The efficacy of methotrexate for maintaining remission in inflammatory bowel disease.
Topics: Diarrhea; Female; Humans; Inflammatory Bowel Diseases; Leukopenia; Male; Methotrexate; Nausea; Remission Induction; Retrospective Studies | 2002 |
Myelodysplasia revealed by seropositive polyarthritis complicated by bicytopenia after the first methotrexate dose.
Topics: Aged; Anemia; Arthritis, Rheumatoid; Fatal Outcome; Humans; Leukopenia; Male; Methotrexate; Myelodysplastic Syndromes; Rheumatoid Factor; Serologic Tests | 2002 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fluorouracil; Humans; Leukopenia; Lung Neoplasms; Male; Mediastinal Neoplasms; Methotrexate; Neoplasm Metastasis; Pneumonia; Retroperitoneal Neoplasms; Teratoma; Testicular Neoplasms; Vinblastine; Vincristine | 1975 |
MACC (methotrexate, adriamycin, cyclophosphamide and CCNU) in advanced lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Drug Therapy, Combination; Female; Heart Diseases; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia | 1979 |
Combination radiotherapy and chemotherapy for small cell carcinoma of the lung.
Topics: Alopecia; Antineoplastic Agents; Arrhythmias, Cardiac; Carcinoma, Small Cell; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Leukopenia; Lung Neoplasms; Methotrexate; Middle Aged; Vomiting | 1979 |
The use of Adriamycin and mehtotrexate in carcinoma of the cervix. The development of a safe effective regimen.
Topics: Alopecia; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Leucovorin; Leukopenia; Methotrexate; Mouth Diseases; Remission, Spontaneous; Taste Disorders; Ulcer; Uterine Cervical Neoplasms | 1978 |
Evaluation of overall toxicity of high-dosage methotrexate regimens.
Topics: Adolescent; Age Factors; Bone Marrow; Bone Neoplasms; Child; Dermatitis; Drug Administration Schedule; Female; Humans; Kidney; Leucovorin; Leukopenia; Liver; Male; Methotrexate; Osteosarcoma; Sex Factors; Stomatitis; Thrombocytopenia; Vincristine | 1979 |
High-dose methotrexate in malignant melanoma.
Topics: Adult; Aged; Female; Humans; Intestinal Neoplasms; Leucovorin; Leukopenia; Male; Melanoma; Methotrexate; Middle Aged; Skin Neoplasms | 1979 |
The proinflammatory function of lymphocytes in non-immune inflammation: effect of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Edema; In Vitro Techniques; Inflammation; Leukocyte Count; Leukopenia; Lymphocyte Transfusion; Lymphocytes; Male; Methotrexate; Rats | 1977 |
Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1978 |
Persistent inflammatory responses enhance the proinflammatory activity of lymphocytes.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Freund's Adjuvant; Inflammation; Leukocyte Count; Leukopenia; Lymphocytes; Male; Methotrexate; Rats | 1978 |
Combination of regional chemotherapy and mastectomy in the treatment of carcinoma of the breast. Five-year results.
Topics: Adult; Aged; Antineoplastic Agents; Brain Diseases; Breast Neoplasms; Cyclophosphamide; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Leukopenia; Mastectomy; Methotrexate; Middle Aged; Pleural Effusion; Wound Healing | 1977 |
A proinflammatory factor in lymphocytes. Its role in the development of acute, non-immunological inflammatory reactions.
Topics: Animals; Carrageenan; Cell Separation; Dextrans; Edema; Granulocytes; Inflammation; Leukocyte Count; Leukocyte Transfusion; Leukocytes; Leukopenia; Lymphocyte Transfusion; Lymphocytes; Methotrexate; Neutrophils; Rats; Transplantation, Homologous | 1976 |
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine | 1975 |
The synergistic effect of salicylates on methotrexate toxicity.
Topics: Anemia, Aplastic; Animals; Drug Synergism; Female; Hematopoiesis; Humans; Leukocyte Count; Leukopenia; Methotrexate; Mice; Retrospective Studies; Salicylates | 1976 |
Effect of recombinant human granulocyte colony-stimulating factor in patients receiving chemotherapy for urogenital cancer. Urological rhG-CSF Study Group.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Evaluation; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukocyte Count; Leukopenia; Male; Methotrexate; Middle Aged; Recombinant Proteins; Urogenital Neoplasms; Vinblastine | 1992 |
Unexpected prolonged myelosuppression after mitomycin, mitoxantrone and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycins; Mitoxantrone; Thrombocytopenia; Time Factors | 1992 |
Intravenous or oral adjuvant CMF for node-positive breast cancer.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Leukopenia; Lymph Node Excision; Lymphatic Metastasis; Mastectomy, Simple; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; New South Wales; Prognosis; Survival Analysis; Survival Rate | 1992 |
Salvage chemotherapy with CCNU and methotrexate for small cell lung cancer resistant to CAV/PE alternating chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Remission Induction; Salvage Therapy; Vincristine | 1991 |
Carboplatin-based combination chemotherapy for advanced carcinoma of the cervix.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Leukopenia; Methotrexate; Middle Aged; Nausea; Remission Induction; Uterine Cervical Neoplasms; Vincristine; Vomiting | 1991 |
[Methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) in advanced urothelial cancer--analysis of efficacy and toxicity].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Evaluation; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Urologic Neoplasms; Vinblastine | 1991 |
MMAF for advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Mitomycins; Prognosis; Stomach Neoplasms | 1991 |
Treatment of primary biliary cirrhosis with low-dose weekly methotrexate.
Topics: Adult; Alkaline Phosphatase; Bilirubin; Biopsy; Cholesterol; Drug Evaluation; Fatigue; Female; Follow-Up Studies; Humans; Leukopenia; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Methotrexate; Middle Aged; Pruritus; Thrombocytopenia; Transaminases | 1991 |
Systemic chemotherapy for urothelial cancer in patients with ureteric obstruction.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Creatinine; Doxorubicin; Epirubicin; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Staging; Ureteral Obstruction; Urinary Bladder Neoplasms; Vinblastine | 1991 |
Higher average received relative dose intensities of cyclophosphamide, methotrexate and 5-fluorouracil using a 24-hour method: implications for improved cure rates in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Prednisone; Remission Induction; Thrombocytopenia; Vincristine | 1990 |
The Duke AFM Program. Intensive induction chemotherapy for metastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Middle Aged; Mucous Membrane; Remission Induction | 1990 |
6-Thioguanine nucleotide accumulation in red blood cells during maintenance chemotherapy for childhood acute lymphoblastic leukemia, and its relation to leukopenia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dose-Response Relationship, Drug; Erythrocytes; Female; Guanine Nucleotides; Humans; Leukopenia; Male; Mercaptopurine; Methotrexate; Monitoring, Physiologic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thionucleotides | 1990 |
[Clinical and pathological evaluations of methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) chemotherapy for advanced urothelial cancers].
Topics: Adult; Aged; Alopecia; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cystectomy; Doxorubicin; Drug Evaluation; Female; Humans; Leukopenia; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Prognosis; Urinary Bladder Neoplasms; Vinblastine; Vomiting | 1990 |
Short term high density systemic therapy for metastatic breast cancer.
Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluoxymesterone; Humans; Leucovorin; Leukopenia; Lung; Methotrexate; Mitolactol; Neoplasm Metastasis; Prednisone; Receptors, Estrogen; Tamoxifen; Thrombocytopenia; Time Factors; Vincristine | 1985 |
[Combination chemotherapy with methotrexate (MTX), vincristine (VCR), cisplatinum (CDDP), cyclophosphamide (CPM), adriamycin (ADM), and bleomycin (BLM); MVP-CAB in patients with advanced urothelial tract cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Remission Induction; Urinary Bladder Neoplasms; Urologic Neoplasms; Vincristine | 1988 |
Do lymphocytes play a pro-inflammatory role in any pharmacological type of rat paw edema?
Topics: Animals; Carrageenan; Dextrans; Edema; Hindlimb; Inflammation; Kaolin; Leukocyte Count; Leukopenia; Lymphocyte Depletion; Lymphocytes; Male; Methotrexate; Rats; Rats, Inbred Strains | 1989 |
Evaluation of management of gestational trophoblastic tumor in National Taiwan University Hospital.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Leucovorin; Leukopenia; Liver; Mercaptopurine; Methotrexate; Middle Aged; Pregnancy; Pregnancy Complications, Neoplastic; Prognosis; Remission Induction; Risk Factors; Taiwan; Trophoblastic Neoplasms; Uterine Neoplasms | 1989 |
[Combination chemotherapy of CPM-MTX-5-FU in non-resectable and recurrent cancer patients].
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Fatigue; Fluorouracil; Humans; Leukopenia; Methotrexate; Nausea; Neoplasm Recurrence, Local; Neoplasms; Remission Induction; Stomach Neoplasms | 1989 |
Felty's syndrome: a therapeutic dilemma?
Topics: Antigen-Antibody Complex; Felty Syndrome; Humans; Infections; Leukopenia; Methotrexate; Neutropenia; Splenectomy | 1989 |
Cyclophosphamide, methotrexate, and 5-fluorouracil in a three-drug admixture. Phase I trial of 14-day continuous ambulatory infusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Stability; Fluorouracil; Humans; Infusions, Intravenous; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia | 1989 |
Three months' treatment with cyclophosphamide, VP-16-213 followed by methotrexate and thoracic radiotherapy for small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Follow-Up Studies; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1985 |
Hepatic metastases in gestational trophoblastic disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Follow-Up Studies; Humans; Leukopenia; Liver Neoplasms; Methotrexate; Middle Aged; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1986 |
Neoadjuvant chemotherapy in the combined modality approach of locally advanced nonmetastatic breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Fluorouracil; Heart Failure; Humans; Leucovorin; Leukopenia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Tamoxifen | 1987 |
The use of low-dose methotrexate for the treatment of allograft rejection is associated with significant drug toxicity.
Topics: Bone Marrow; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Leukocyte Count; Leukopenia; Methotrexate; Time Factors | 1988 |
[Prevention of cancer chemotherapeutic agent-induced toxicity in postoperative breast cancer patients with glycyrrhizin (SNMC)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Leukopenia; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Postoperative Care; Tegafur | 1986 |
Treatment of refractory lymphoma with methotrexate, VM-26 (teniposide), procarbazine, and dexamethasone: Cancer and Leukemia Group B study 7902.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Evaluation; Female; Humans; Leucovorin; Leukopenia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neutropenia; Procarbazine; Teniposide; Thrombocytopenia; Vincristine | 1988 |
[Methotrexate poisoning: value of exchange transfusion].
Topics: Acute Kidney Injury; Child; Exchange Transfusion, Whole Blood; Humans; Leukopenia; Male; Methotrexate; Osteosarcoma; Thrombocytopenia | 1987 |
Further studies of the mechanism of counter irritation by turpentine.
Topics: Animals; Blood Sedimentation; Captopril; Carrageenan; Edema; Female; Inflammation; Kininogens; Leukopenia; Male; Methotrexate; Methysergide; Pyrilamine; Rats; Rats, Inbred Strains; Turpentine; Zymosan | 1986 |
Third-line chemotherapy for resistant Hodgkin's disease with lomustine, etoposide, and methotrexate.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Hodgkin Disease; Humans; Leukopenia; Lomustine; Male; Methotrexate; Middle Aged | 1987 |
Toxicity of methotrexate in rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Female; Follow-Up Studies; HLA Antigens; Humans; Leukopenia; Male; Meningitis, Listeria; Methotrexate; Middle Aged; Pulmonary Fibrosis; Retrospective Studies; Seizures | 1987 |
[Acute bone marrow suppression with low-dosage methotrexate].
Topics: Aged; Arthritis, Rheumatoid; Bone Marrow; Female; Half-Life; Humans; Leukopenia; Methotrexate; Pancytopenia; Psoriasis; Thrombocytopenia | 1987 |
Modulation of high-dose methotrexate toxicity by a non-toxic level of 5-fluorouracil.
Topics: Animals; Body Weight; Erythrocyte Count; Fluorouracil; Hematocrit; Hemoglobins; Leukocyte Count; Leukopenia; Male; Methotrexate; Mice; Platelet Count; Time Factors | 1986 |
Ten-year experience with CMF-based adjuvant chemotherapy in resectable breast cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Leukopenia; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Prognosis; Receptors, Estrogen; Retrospective Studies; Tamoxifen | 1985 |
Rescue from high-dose methotrexate with 5-methyltetrahydrofolate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Nausea; Tetrahydrofolates; Vomiting | 1986 |
Cytotoxic chemotherapy and androgen priming in patients with advanced carcinoma of the prostate. A phase II trial of the Piedmont Oncology Association.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Drug Evaluation; Fluoxymesterone; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Vincristine | 1985 |
Involvement of lymphocytes in non-immune inflammation: dual effect of glucocorticoids.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Carrageenan; Glucocorticoids; Inflammation; Leukopenia; Lymphocyte Transfusion; Lymphocytes; Male; Methotrexate; Metyrapone; Rats; Rats, Inbred Strains | 1985 |
[Cytostatic therapy of bronchial carcinoma].
Topics: Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Humans; Leukopenia; Methotrexate; Palliative Care; Procarbazine; Thrombocytopenia; Triaziquone; Vincristine | 1972 |
[Therapy of bronchial carcinoma. Intermittent high-dosage polychemotherapy of bronchial carcinoma in combination with radical surgery for the prevention of recurrences and in primarily inoperable patients].
Topics: Adult; Aged; Antineoplastic Agents; Austria; Bronchial Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Palliative Care | 1973 |
[Treatment of epidermoid carcinoma of the oro-pharyngo-laryngeal area with combination of methotrexate and bleomycin].
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms; Thrombocytopenia | 1974 |
The effect of treatment with cyclophosphamide alone or in combination with methotrexate on lymphocyte transformation and immunoglobulin concentration.
Topics: Bronchial Neoplasms; Cyclophosphamide; gamma-Globulins; Humans; In Vitro Techniques; Leukopenia; Lymphocyte Activation; Lymphocytes; Methotrexate; Mitosis | 1969 |
Triple massive-dose drug therapy in combined treatment of advanced ovarian carcinoma.
Topics: Carcinoma; Cyclophosphamide; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Leukopenia; Long-Term Care; Methotrexate; Ovarian Neoplasms; Podophyllin; Prognosis | 1973 |
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".
Topics: Adult; Aged; Anemia; Carcinoma, Squamous Cell; Cell Division; Drug Eruptions; Drug Synergism; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Leukopenia; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Mucous Membrane; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1970 |
The variability of individual tolerance to methotrexate in cancer patients.
Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting | 1971 |
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
Combination chemotherapy in accelerated phase of chronic granulocytic leukemia.
Topics: Adolescent; Adult; Aged; Anemia; Blood Platelets; Blood Transfusion; Blood Urea Nitrogen; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytomegalovirus; Female; Fever; Hemorrhage; Humans; Jaundice; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nocardia Infections; Pneumonia; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Thrombocytopenia; Vincristine | 1969 |
[L-Asparaginase in the treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Asparaginase; Child, Preschool; Drug Hypersensitivity; Drug Tolerance; Hematopoiesis; Humans; Immunosuppressive Agents; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver Function Tests; Methotrexate; Middle Aged; Prednisone; Vincristine | 1970 |
[Proresid-methotrexate combination in chemotherapy of orofacial carcinoma].
Topics: Agranulocytosis; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Humans; Infections; Injections, Intra-Arterial; Leukopenia; Lip Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Tongue Neoplasms | 1970 |
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia | 1971 |
Methotrexate treatment for advanced bladder cancer.
Topics: Aged; Blood Cell Count; Carcinoma, Transitional Cell; Creatinine; Diarrhea; Humans; Kidney Function Tests; Kidney Neoplasms; Leukopenia; Lymphatic Metastasis; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Metastasis; Urea; Urinary Bladder; Urinary Bladder Neoplasms; Urography; Vomiting | 1974 |
Daunorubicin in the therapy of acute granulocytic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Female; Humans; Hydrazines; Hyperplasia; Leukemia, Myeloid; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thrombocytopenia; Time Factors | 1973 |
Combination chemotherapy in disseminated carcinoma of the breast.
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Feeding and Eating Disorders; Female; Fluorouracil; Humans; Leukopenia; Methotrexate; Nausea; Neoplasm Metastasis; Pneumonia; Prednisone; Thrombocytopenia; Vincristine | 1974 |
Evaluation of induction of remission, intensification, and central nervous system prophylactic treatment in acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infections; Injections, Spinal; Leukemia, Lymphoid; Leukopenia; Male; Methotrexate; Middle Aged; Radiotherapy Dosage; Remission, Spontaneous | 1974 |
1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) given alone and combined with antimetabolites in the treatment of advanced solid tumors.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cystadenoma; Cytarabine; Female; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Nausea; Neoplasm Metastasis; Neoplasms; Nitrosourea Compounds; Ovarian Neoplasms; Stomach Neoplasms; Vomiting | 1972 |
Methrotrexate U.S.P. (amethopterin) and methotrexate sodium.
Topics: Abortion, Induced; Anemia; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Choriocarcinoma; Drug Interactions; Female; Humans; Leukemia; Leukopenia; Male; Methotrexate; Neoplasms; Pregnancy; Psoriasis; Skin Diseases; Testicular Neoplasms; Thrombocytopenia; Uric Acid; Uterine Neoplasms | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine | 1973 |
Multiple-drug therapy for malignant solid tumors in adults.
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Vincristine | 1973 |
Cancer chemotherapy by intra-arterial infusion with adriamycin.
Topics: Adult; Alopecia; Anemia; Doxorubicin; Electrocardiography; Female; Femoral Artery; Fluorouracil; Heart; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Thrombocytopenia | 1973 |
Intra-arterial cancer chemotherapy with combined anticancer agents.
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intra-Arterial; Leukopenia; Liver Neoplasms; Methotrexate; Middle Aged; Mitomycins; Neoplasms, Connective Tissue; Pyridoxal Phosphate; Stomach Neoplasms; Vinblastine; Vincristine | 1973 |
Polymyositis and dermatomyositis: combined methotrexate and corticosteroid therapy.
Topics: Adolescent; Adult; Aged; Creatine Kinase; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leg Ulcer; Leukopenia; Liver Function Tests; Lung Diseases; Male; Methotrexate; Middle Aged; Muscles; Myositis; Prednisone; Stomatitis | 1974 |
Five-drug therapy in advanced breast cancer: factors influencing toxicity and response.
Topics: Administration, Oral; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Female; Fluorouracil; Follow-Up Studies; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Prednisone; Vincristine | 1974 |
Antiserum to lymphocytes: interactions with chemical immunosuppressants.
Topics: Animals; Cell Differentiation; Cortisone; Immune Sera; Immune Tolerance; Immunosuppressive Agents; Leukopenia; Lymphocytes; Methotrexate; Mice; Rabbits; Skin Transplantation; Transplantation Immunology | 1968 |
Clinical experience with L-asparaginase.
Topics: Adolescent; Adult; Aged; Asparaginase; Azaserine; Burkitt Lymphoma; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Escherichia coli; Female; Humans; Leukemia, Lymphoid; Leukopenia; Lymphoma, Non-Hodgkin; Lymphopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms; Pancreatitis; Thrombocytopenia | 1970 |
Phase I study of phenesterin (NSC-104469).
Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Breast Neoplasms; Chlorambucil; Cholestanes; Cyclophosphamide; Estrogens; Fluorouracil; Glucocorticoids; Humans; Leukocyte Count; Leukopenia; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Secosteroids; Stomatitis; Tachycardia; Thiotepa; Vincristine | 1971 |
Effects of nitrogen mustard, methotrexate and hydrocortisone on cell replication in rat ileum and spleen.
Topics: Anemia; Animals; Autoradiography; Blood Cell Count; Body Weight; DNA; DNA Replication; Hydrocortisone; Ileum; Leukopenia; Lymphocytes; Male; Methotrexate; Mitosis; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Spleen; Thymidine; Tritium | 1972 |
Evaluation of the combination of hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in carcinoma of the lung.
Topics: Administration, Oral; Amines; Antineoplastic Agents; Carcinoma, Bronchogenic; Diarrhea; Evaluation Studies as Topic; Humans; Injections, Intramuscular; Leukopenia; Lung Neoplasms; Methotrexate; Nausea; Remission, Spontaneous; Stomatitis; Thrombocytopenia; Triazines; Vomiting | 1971 |
Treatment of AGL.
Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine | 1969 |
Studies on preoperative cancer chemotherapy. Methods of preoperative intra-arterial infusion by the use of methotrexate or vinblastine.
Topics: Adult; Aged; Catheterization; Chromosomes; Coloring Agents; DNA; Female; Humans; Injections, Intra-Arterial; Leukopenia; Male; Methods; Methotrexate; Middle Aged; Preoperative Care; Stomach Neoplasms; Vinblastine | 1969 |
[72 cases of psoriasis treated by methotrexate].
Topics: Adolescent; Adult; Biopsy; Child; Female; Humans; Leukopenia; Liver; Male; Methotrexate; Middle Aged; Prognosis; Psoriasis; Thrombocytopenia | 1969 |
Clinical immunologic responsiveness in malignant disease. I. Delayed hypersensitivity reaction and the effect of cytotoxic drugs.
Topics: Adolescent; Adult; Aged; Antigens; Antineoplastic Agents; Breast Neoplasms; Candida; Child; Child, Preschool; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mumps virus; Neoplasms; Nitrobenzenes; Ovarian Neoplasms; Skin Tests; Tuberculin; Uterine Cervical Neoplasms; Vinblastine | 1970 |
[Methotrexate in the treatment of psoriasis].
Topics: Adult; Aged; Asthenia; Chemical and Drug Induced Liver Injury; Female; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1970 |
Acute toxicity of five insect chemosterilants, hemel, hempa, tepa, metepa, and methotrexate, for cockerels.
Topics: Amines; Animals; Azirines; Chemosterilants; Chickens; Female; Glutamates; Infertility; Insecticides; Leukocyte Count; Leukopenia; Male; Methotrexate; Organ Size; Phosphines; Phosphoric Acids; Spleen; Testis | 1970 |
[Preparation of swine antilymphocyte serum and its effect on the peripheral blood picture in swine].
Topics: Agglutination Tests; Animals; Antilymphocyte Serum; Female; Leukocytes; Leukopenia; Methotrexate; Phagocytosis; Swine; Swine Diseases | 1970 |
Methotrexate for psoriasis. A new therapeutic schedule.
Topics: Administration, Oral; Alopecia; Humans; Injections, Intramuscular; Leukopenia; Methotrexate; Mouth Diseases; Nausea; Prognosis; Psoriasis; Thrombocytopenia; Ulcer; Urticaria | 1971 |
[Further proposals for chemotherapeutic prophylaxis of recurrence of bronchial carcinoma].
Topics: Antibiotics, Antineoplastic; Bronchial Neoplasms; Cyclophosphamide; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasm Metastasis; Prognosis; Vinblastine | 1971 |
Methotrexate and the platelet count.
Topics: Antineoplastic Agents; Azathioprine; Blood Cell Count; Blood Platelets; Fluorouracil; Humans; Leukopenia; Methotrexate; Neoplasms; Thrombocytopenia; Thrombocytosis; Time Factors | 1968 |
Methotrexate in psoriasis.
Topics: Adult; Aged; Female; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Nausea; Psoriasis | 1968 |
Methotrexate for psoriasis in weekly oral doses.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anemia; Aspartate Aminotransferases; Child; Female; Folic Acid Antagonists; Follow-Up Studies; Humans; Kidney Function Tests; Leukopenia; Liver Function Tests; Male; Methotrexate; Middle Aged; Psoriasis; Thrombocytopenia | 1969 |
Clinical investigations in the treatment of meningeal leukemia: radiation therapy regimens vs. conventional intrathecal methotrexate.
Topics: Adolescent; Blood Cell Count; Bone Marrow Examination; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Injections, Spinal; Leukemia; Leukopenia; Male; Methotrexate; Radiotherapy | 1969 |
The treatment of psoriasis with parenteral methotrexate.
Topics: Adult; Aged; Anemia; Aspartate Aminotransferases; Female; Humans; Infusions, Parenteral; Leukopenia; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged; Nausea; Psoriasis; Schilling Test | 1966 |
Patient protection in cancer chemotherapy.
Topics: Adult; Anti-Bacterial Agents; Culture Media; Cyclophosphamide; Fluorouracil; Germ-Free Life; Humans; Leukemia; Leukopenia; Male; Mercaptopurine; Methotrexate; Prednisolone; Teratoma; Vincristine | 1966 |
[On the effectiveness of methotrexate in the treatment of psoriasis vulgaris].
Topics: Adolescent; Adult; Aged; Female; Folliculitis; Humans; Injections, Intravenous; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Mucosa; Nausea; Prurigo; Psoriasis; Ulcer | 1966 |