methotrexate has been researched along with Leukemia, T-Cell in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (37.14) | 18.2507 |
| 2000's | 14 (40.00) | 29.6817 |
| 2010's | 8 (22.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hussein, K; Kreipe, H; Maecker-Kolhoff, B; Teiken, K | 1 |
| Le, Y; Li, H; Liu, Z; Long, Y; Wan, C | 1 |
| Aaroe, AE; Nevel, KS | 1 |
| Araya, T; Imataki, O; Kida, J; Kimura, N; Matsumoto, K; Takahashi, T; Uemura, M | 1 |
| Abujamra, AL; Brunetto, AL; dos Santos, MP; Roesler, R; Schwartsmann, G | 1 |
| Efferth, T; Fu, YJ; Konkimalla, VB; Kramer, A; Radlwimmer, B; Sültmann, H; Youns, M; Zu, YG | 1 |
| Suzuki, R | 2 |
| Fegan, A; Kumarapperuma, SC; Wagner, CR | 1 |
| Centurioni, R; Corvatta, L; Leoni, F; Leoni, P; Malerba, L; Marconi, M; Masia, MC; Mele, A; Offidani, M; Scortechini, A | 1 |
| Ando, Y; Asai, S; Kobayashi, H; Miyachi, H; Takemura, Y | 1 |
| Greenberg, ML; Hitzler, JK; Maze, R; Nathan, PC; Spiegler, B; Weitzman, S | 1 |
| Catovsky, D; Matutes, E; Osuji, N; Wotherspoon, A | 1 |
| Kneba, M; Moosig, F; Schoch, R | 1 |
| Haile, WH; McGuire, JJ; Yeh, CC | 1 |
| Catovsky, D; Del Giudice, I; Grech, H; Matutes, E; Osuji, N; Swansbury, JG; Tjonnfjord, G; Wotherspoon, A | 1 |
| Kinoshita, T; Murata, M; Naoe, T; Narimatsu, H; Sugimoto, K; Terakura, S | 1 |
| Ando, Y; Kobayashi, H; Miyachi, H; Takemura, Y | 2 |
| Ireland, CM; Pittman, SM; Strickland, D | 1 |
| Beck, WT; Danks, MK; Hill, AB; Thompson, FH; Trent, JM | 1 |
| Banks, S; Dev, IK; Dickerson, SH; Duch, DS; Ferone, R; Heath, LS; Humphreys, J; Knick, V; Pendergast, W; Singer, S | 1 |
| Kavallaris, M; Pittman, SM; Stewart, BW | 1 |
| Galvin, JM; Haile, WH; McGuire, JJ; Russell, CA; Shane, B | 1 |
| Hukku, B; Matherly, LH; Pullen, J; Ravindranath, Y; Taub, JW; Williamson, M; Wong, SC; Zhang, L | 1 |
| Gifford, AJ; Haber, M; Kavallaris, M; Madafiglio, J; Matherly, LH; Norris, MD; Stewart, BW | 1 |
| McGuire, JJ; Russell, CA | 1 |
| Billio, A; Coser, P; Fabris, P; Pescosta, N; Rosanelli, C | 1 |
| Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; Veerman, AJ | 1 |
| Catts, VS; Farnsworth, ML; Haber, M; Lock, RB; Lutze-Mann, LH; Norris, MD | 1 |
| Go, RS; Li, CY; Phyliky, RL; Tefferi, A | 1 |
| Alvarez, E; García, MG; Hajos, SE; Lopes, EC; Vellón, L | 1 |
| Bensinger, WI; Bernabei, PA | 1 |
| Brian, MJ; Haber, M; Kavallaris, M; Lutze, LH; Norris, MD; Stewart, BW; White, L | 1 |
| Cotter, TG; Lennon, SV; Martin, SJ | 1 |
6 review(s) available for methotrexate and Leukemia, T-Cell
| Article | Year |
|---|---|
Central Nervous System Involvement of Natural Killer and T Cell Neoplasms.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Humans; Killer Cells, Natural; Leukemia, T-Cell; Lymphoma, Non-Hodgkin; Methotrexate; Prognosis; T-Lymphocytes | 2019 |
Treatment of advanced extranodal NK/T cell lymphoma, nasal-type and aggressive NK-cell leukemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dexamethasone; Drug Therapy, Combination; Etoposide; Humans; Ifosfamide; Killer Cells, Natural; Leukemia, T-Cell; Lymphoma, Extranodal NK-T-Cell; Methotrexate; Treatment Outcome | 2010 |
NK/T-cell lymphomas: pathobiology, prognosis and treatment paradigm.
Topics: Antineoplastic Combined Chemotherapy Protocols; Herpesvirus 4, Human; Humans; Killer Cells, Natural; Leukemia, T-Cell; Lymphoma, T-Cell; Methotrexate; Nose Neoplasms; Prognosis; Protein Kinase Inhibitors | 2012 |
[T-large granular lymphocyte leukaemia. An important differential diagnosis to Felty's syndrome].
Topics: Antirheumatic Agents; Antiviral Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Felty Syndrome; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Leukemia, T-Cell; Methotrexate; Vidarabine | 2006 |
T-cell large granular lymphocyte leukemia: A report on the treatment of 29 patients and a review of the literature.
Topics: Adult; Aged; Aged, 80 and over; Cyclophosphamide; Cyclosporine; Databases as Topic; Female; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Leukemia, T-Cell; Male; Methotrexate; Middle Aged; Pentostatin; Retrospective Studies | 2006 |
Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia.
Topics: Acute Disease; Animals; Child; Drug Administration Schedule; Drug Resistance, Neoplasm; Folic Acid Antagonists; Humans; Leukemia, B-Cell; Leukemia, Myeloid; Leukemia, T-Cell; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2000 |
1 trial(s) available for methotrexate and Leukemia, T-Cell
| Article | Year |
|---|---|
High-dose daunorubicin as liposomal compound (Daunoxome) in elderly patients with acute lymphoblastic leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Bone Marrow Diseases; Burkitt Lymphoma; Comorbidity; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Carriers; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, T-Cell; Life Tables; Liposomes; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Safety; Survival Analysis; Topotecan; Treatment Outcome | 2003 |
28 other study(ies) available for methotrexate and Leukemia, T-Cell
| Article | Year |
|---|---|
Variant of classical high grade PTLD: post-transplant EBV-negative T cell lymphoblastic leukaemia after solid organ transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biliary Atresia; Bone Marrow; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Fatal Outcome; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Infant; Leukemia, T-Cell; Liver Transplantation; Lung Transplantation; Lymph Nodes; Male; Mercaptopurine; Methotrexate; Postoperative Complications; Prednisone; Remission Induction; Vincristine | 2017 |
Rhabdomyolysis during myelosuppression in a patient with central nervous system leukemia: A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Fatal Outcome; Humans; Leukemia, T-Cell; Male; Methotrexate; Rhabdomyolysis; Vincristine; Young Adult | 2018 |
[Picture in clinical hematology no. 69--Case of asymptomatic limbic leukoencephalopathy due to methotrexate therapy].
Topics: Acute Disease; Antimetabolites, Antineoplastic; Asymptomatic Diseases; Humans; Injections, Spinal; Leukemia, T-Cell; Leukoencephalopathies; Limbic System; Magnetic Resonance Imaging; Male; Methotrexate; Young Adult | 2014 |
Sodium butyrate enhances the cytotoxic effect of antineoplastic drugs in human lymphoblastic T-cells.
Topics: Antineoplastic Agents; Bleomycin; Butyrates; Cell Proliferation; Cytarabine; Doxorubicin; Drug Synergism; Etoposide; Humans; Jurkat Cells; Leukemia, T-Cell; Methotrexate; T-Lymphocytes; Vincristine | 2009 |
Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Chalcones; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Inhibitory Concentration 50; Jurkat Cells; Leukemia, T-Cell; Methotrexate; Microarray Analysis; Pharmacogenetics; RNA, Messenger | 2010 |
Chemically self-assembled antibody nanostructures as potential drug carriers.
Topics: Antibodies, Monoclonal; CD3 Complex; Cell Proliferation; Chromatography, Gel; Drug Carriers; Flow Cytometry; Humans; Leukemia, T-Cell; Methotrexate; Microscopy, Confocal; Microscopy, Fluorescence; Nanostructures; Recombinant Fusion Proteins; Single-Chain Antibodies; Tetrahydrofolate Dehydrogenase | 2012 |
Large diversity in transport-mediated methotrexate resistance in human leukemia cell line CCRF-CEM established in a high concentration of leucovorin.
Topics: Amino Acid Substitution; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Codon; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Inhibitory Concentration 50; Intracellular Fluid; Leucovorin; Leukemia, T-Cell; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mutation, Missense; Neoplasm Proteins; Point Mutation; Selection, Genetic; Sequence Deletion; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured | 2003 |
CNS-directed therapy in young children with T-lineage acute lymphoblastic leukemia: High-dose methotrexate versus cranial irradiation.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child, Preschool; Cohort Studies; Cranial Irradiation; Female; Humans; Infant; Leukemia, T-Cell; Male; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate | 2004 |
Lessons from a case of T-cell large granular lymphocytic leukaemia suggesting that immunomodulatory therapy is more effective than intensive treatment.
Topics: Adult; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Humans; Immunosuppressive Agents; Immunotherapy; Leukemia, T-Cell; Male; Methotrexate; Peripheral Blood Stem Cell Transplantation; T-Lymphocytes | 2005 |
5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.
Topics: Aminoimidazole Carboxamide; Biological Transport; Cell Line, Tumor; Child; Dose-Response Relationship, Drug; Drug Synergism; Folic Acid Antagonists; Humans; Kinetics; Leukemia, T-Cell; Membrane Transport Proteins; Methotrexate; Phosphoribosylglycinamide Formyltransferase; Polyglutamic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Ribonucleotides; Subcellular Fractions; Temperature; Thymidylate Synthase; Tritium | 2006 |
Successful umbilical cord blood transplantation using a reduced-intensity preparative regimen without total body irradiation and tacrolimus plus methotrexate for prophylaxis of graft-versus-host disease in a patient with adult T-cell leukemia/lymphoma.
Topics: Female; Fetal Blood; Graft vs Host Disease; Humans; Leukemia, T-Cell; Lymphoma, T-Cell; Methotrexate; Middle Aged; Skin Neoplasms; Stem Cell Transplantation; Tacrolimus; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation | 2007 |
Expression of variant dihydrofolate reductase with decreased binding affinity to antifolates in MOLT-3 human leukemia cell lines resistant to trimetrexate.
Topics: Base Sequence; DNA Primers; Drug Resistance; Folic Acid Antagonists; Humans; In Vitro Techniques; Kinetics; Leukemia, T-Cell; Methotrexate; Molecular Sequence Data; RNA, Messenger; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured | 1995 |
Polymerization of tubulin in apoptotic cells is not cell cycle dependent.
Topics: Apoptosis; Cell Cycle; Dexamethasone; DNA, Neoplasm; Humans; Immunohistochemistry; Ki-67 Antigen; Leukemia, T-Cell; Methotrexate; Neoplasm Proteins; Nuclear Proteins; Polymers; Tubulin; Tumor Cells, Cultured; Vincristine | 1994 |
Loss of tumorigenicity in a methotrexate-resistant human leukemia cell line.
Topics: Animals; Chromosome Aberrations; Chromosome Disorders; Drug Resistance; Folic Acid; Genes; Humans; Karyotyping; Leukemia, T-Cell; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Tetrahydrofolate Dehydrogenase; Translocation, Genetic; Tumor Cells, Cultured | 1993 |
Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Division; Colonic Neoplasms; Female; Humans; Indoles; Isoindoles; Leucovorin; Leukemia L1210; Leukemia, T-Cell; Methotrexate; Quinazolines; Structure-Activity Relationship; Subrenal Capsule Assay; Tetrahydrofolates; Thymidylate Synthase | 1993 |
Karyotypic analysis of CCRF-CEM and drug-resistant cell lines with stable and unstable ploidy.
Topics: Chromosome Aberrations; Chromosomes, Human, Pair 8; Drug Resistance; Gene Deletion; Humans; Karyotyping; Leukemia, T-Cell; Methotrexate; Ploidies; Polyploidy; Tumor Cells, Cultured; Vincristine | 1993 |
Evolution of drug resistance in CCRF-CEM human leukemia cells selected by intermittent methotrexate exposure.
Topics: Antimetabolites, Antineoplastic; Cell Division; DNA, Neoplasm; Drug Resistance, Neoplasm; Humans; Leukemia, T-Cell; Methotrexate; Polyglutamic Acid; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Tritium; Tumor Cells, Cultured | 1995 |
Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, T-Cell; Methotrexate; Oxidation-Reduction; Trimetrexate; Tumor Cells, Cultured | 1997 |
Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
Topics: Adolescent; Amino Acid Sequence; Antimetabolites, Antineoplastic; Carrier Proteins; Child; Child, Preschool; Female; Gene Expression; Humans; Immunophenotyping; Infant; K562 Cells; Leukemia, T-Cell; Male; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Molecular Sequence Data; Ploidies; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; Tritium; Tumor Cells, Cultured | 1998 |
P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene.
Topics: Amino Acid Sequence; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia, T-Cell; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Molecular Sequence Data; Point Mutation; Reduced Folate Carrier Protein; Sequence Homology, Amino Acid; Tumor Cells, Cultured; Vincristine | 1998 |
Folylpolyglutamate synthetase expression in antifolate-sensitive and -resistant human cell lines.
Topics: Amino Acid Sequence; Animals; Antibodies; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Half-Life; Humans; Leukemia, T-Cell; Methotrexate; Molecular Sequence Data; Peptide Fragments; Peptide Synthases; Rabbits; Tumor Cells, Cultured | 1998 |
A brief intensive chemotherapy in T-prolymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Ifosfamide; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Methotrexate; Middle Aged; Pentostatin; Prognosis; T-Lymphocyte Subsets; Transplantation, Autologous; Vincristine | 2000 |
High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.
Topics: Active Transport, Cell Nucleus; Alleles; Antineoplastic Agents; Child; Cytarabine; Dexamethasone; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucocorticoids; Humans; Leukemia, T-Cell; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polymorphism, Restriction Fragment Length; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Receptors, Glucocorticoid; RNA, Messenger; RNA, Neoplasm; Selection, Genetic; Sequence Analysis, DNA; Tumor Cells, Cultured | 2001 |
Acquired pure red cell aplasia associated with lymphoproliferative disease of granular T lymphocytes.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Cyclophosphamide; Cyclosporine; Female; Humans; Immunosuppressive Agents; Leukemia, T-Cell; Male; Methotrexate; Middle Aged; Neutropenia; Prednisone; Recurrence; Red-Cell Aplasia, Pure; Remission Induction; T-Lymphocytes, Cytotoxic | 2001 |
Correlation between decreased apoptosis and multidrug resistance (MDR) in murine leukemic T cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Leukemia, T-Cell; Methotrexate; Mice; Tumor Cells, Cultured; Vincristine | 2001 |
Differential effect of the combination methotrexate/(dl)-5-methyltetrahydrofolate on lymphoid malignant and normal bone marrow cells.
Topics: Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukemia, B-Cell; Leukemia, T-Cell; Methotrexate; Tetrahydrofolates; Time Factors; Tumor Stem Cell Assay | 1992 |
Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T-cell leukemia xenograft, LALW-2.
Topics: Animals; Cell Division; Drug Resistance; Gene Amplification; Gene Expression; Humans; Leukemia, T-Cell; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Tetrahydrofolate Dehydrogenase; Transplantation, Heterologous; Tumor Cells, Cultured | 1991 |
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.
Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorambucil; DNA Damage; Ethanol; Hot Temperature; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukemia, B-Cell; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Methotrexate; Molecular Weight; Tumor Cells, Cultured | 1991 |