Compounds > methotrexate
Page last updated: 2024-08-25

methotrexate and Leukemia, Pre-B-Cell

methotrexate has been researched along with Leukemia, Pre-B-Cell in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's23 (25.84)18.2507
2000's24 (26.97)29.6817
2010's33 (37.08)24.3611
2020's9 (10.11)2.80

Authors

AuthorsStudies
Alvarado, Y; Dabaja, B; Garcia-Manero, G; Garris, R; Haddad, FG; Jabbour, E; Jacob, J; Jain, N; Jorgensen, J; Kadia, T; Kanagal-Shamanna, R; Kantarjian, H; Kebriaei, P; Khouri, I; Loghavi, S; O'Brien, S; Paul, S; Ravandi, F; Sasaki, K; Short, NJ; Yilmaz, M1
Canevarolo, RR; Cury, NM; Yunes, JA1
Jabbour, EJ; Kadia, TM; Kantarjian, HM; Rausch, CR1
Amigo, ML; Bravo-Perez, C; Escobar, H; Garcia, J; Garcia-Malo, MD; Muiña, B; Ortuño, FJ; Pajares, I; Piris, MA; Rodriguez-Pinilla, SM1
Alvarado-Valero, Y; Burger, J; Cortes, J; Daver, N; Di Nardo, CD; Estrov Md, Z; Garcia-Manero, G; Garris, R; Ingram, A; Jabbour, E; Jain, N; Jorgensen, J; Kadia, T; Kantarjian, H; Khoury, J; Konopleva Md PhD, M; Ohanian DO, M; OʼBrien, S; Pierce, S; Ravandi-Kashani, F; Sasaki, K; Short, NJ; Wang, SA; Wierda, W; Yilmaz, M1
Abedi, M; Esmaeili, A; Rahgozar, S1
Borowitz, MJ; Burke, MJ; Carroll, AJ; Carroll, WL; Dai, Y; Devidas, M; Gore, L; Hardy, KK; Heerema, NA; Hilden, JM; Hunger, SP; Kairalla, JA; Larsen, E; Loh, ML; Rabin, KR; Raetz, EA; Salzer, WL; Winick, N; Wood, B; Zweidler-McKay, PA1
Wang, J; Xiong, Y1
Agarwal, P; Manimaran, PA; Ramasundaram, M; Sundaram, J1
Borowitz, MJ; Carroll, A; Carroll, WL; Chen, S; Devidas, M; Gastier-Foster, JM; Heerema, NA; Hunger, SP; Larsen, E; Loh, ML; Maloney, K; Mattano, L; Raetz, E; Willman, C; Winick, N; Wood, B1
Fruman, DA; Khaw, A; Konopleva, M; Lee, JS; Lu, M; Lui, B; Mallya, S; Müschen, M; Nguyen, D; Pandori, W; Vo, TT1
Armstrong, D; Carroll, WL; Devidas, M; Embry, L; Hardy, KK; Helian, S; Hunger, S; Kairalla, JA; Larsen, E; Loh, ML; Noll, RB; Raetz, EA; Relling, MV; Winick, N; Yang, W1
Li, D; Wu, Z; Xu, YL1
Aplenc, R; Cahen, V; Carroll, WL; Devidas, M; DiNofia, AM; Fisher, BT; Hall, M; Huang, YV; Hunger, SP; Larsen, EC; Li, Y; Seif, AE; Winick, NJ1
Bordbar, M; Fattahi, M; Haghpanah, S; Honar, N; Shakibazad, N1
Einzmann, T; Isachenko, E; Isachenko, V; Ludwig, S; Mallmann, P; Rahimi, G; Salama, M1
Attarbaschi, A; Beier, R; Lauten, M; Möricke, A; Niggli, F; Odenwald, E; Schrappe, M; Stanulla, M; Zimmermann, M1
Karawajew, L; Ludwig, WD; Möricke, A; Ratei, R; Schabath, R; Schrappe, M; Zimmermann, M1
Bostrom, B; Gandrud, L; Melachuri, S1
Akagi, T; Hofmann, WK; Jann, JC; Kato, M; Kawamata, N; Klaumünzer, M; Koeffler, HP; Liem, NL; Lock, RB; Marshall, GM; Mossner, M; Nowak, D; Nowak, V; Ogawa, S; Okamoto, R; Papa, RA; Sanada, M; Thoennissen, NH1
Chinello, M; Locasciulli, A; Naviglio, S; Severino, A; Shardlow, A; Ventura, A1
Bayhan, T; Çetin, M; Gümrük, F; Ünal, Ş1
Borowitz, MJ; Carroll, AJ; Carroll, WL; Dai, Y; Devidas, M; Gastier-Foster, JM; Heerema, NA; Hunger, SP; Larsen, E; Loh, ML; Nachman, JB; Raetz, EA; Salzer, WL; Willman, CL; Winick, NJ; Wood, BL1
Akahoshi, Y; Ashizawa, M; Harada, N; Ishihara, Y; Kako, S; Kameda, K; Kanda, J; Kanda, Y; Kawamura, K; Kikuchi, M; Kimura, SI; Nakano, H; Nakasone, H; Nishida, J; Sakamoto, K; Sato, M; Terasako-Saito, K; Ugai, T; Wada, H; Yamasaki, R; Yamazaki, R1
Borowitz, MJ; Carroll, AA; Carroll, WL; Chen, S; Cole, C; Devidas, M; Eicher, A; Gastier-Foster, JM; Haugan, M; Heerema, NA; Hunger, SP; Larsen, EC; Loh, ML; Mattano, LA; Raetz, EA; Salzer, WL; Sorenson, M; Willman, CL; Winick, NJ; Wood, BL1
Amin, K; Barbarotta, L; Gore, SD; Kasberg, S; Kim, TK; Podoltsev, NA; Prebet, T; Roche, K; Stahl, M; Xu, ML; Zeidan, AM1
Cruz, AT; Shah, MD; Shim, YH; Stevens, AM; Subrahmanian, KN; Tran, BH1
Khoury, JD; Thakral, B1
Abdalla, B; Alfaar, AS; Awad, M; Rashed, WM; Taha, H; Zekri, W1
Hara, J; Hori, H; Horibe, K; Kato, K; Kobayashi, R; Komada, Y; Kudoh, T; Matsuo, K; Nishimura, S; Oda, M; Tanizawa, A; Tawa, A; Usami, I; Yoshida, M; Yumura-Yagi, K1
Alpern, ER; Thomas, N1
Cornelissen, JJ; Schnog, JB; Van Hest, RM; Van't Veer, MB1
Cortes, J; Faderl, S; Garcia-Manero, G; Huh, Y; Jorgensen, JL; Kantarjian, HM; Keating, MJ; Koller, C; O'Brien, S; Pierce, S; Thomas, DA; Verstovsek, S; Wierda, W1
Burgaleta, C; de Miguel, D; García-Suárez, J; Gil-Fernández, JJ; Martín, Y1
Abe, A; Hayasaka, K; Kawakami, K; Kawano, Y; Kumamoto, T; Nishikawa, T; Okamoto, Y; Tonooka, S1
Faderl, S; Garg, R; Kantarjian, H; Lovshe, D; O'Brien, S; Pierce, S; Ravandi, F; Thomas, D1
Kocum, AI; Malbora, B; Ozbek, N; Ozyurek, E1
Dhall, G; Ettinger, LJ; Lastra, C; Mahadeo, KM; Panigrahy, A1
Forestier, E; Gustafsson, G; Heyman, M; Kristinsson, J; Lausen, B; Rosthoej, S; Schmiegelow, K; Schroeder, H; Vettenranta, K; Wesenberg, F1
Dürken, M; Karremann, M; Neumaier-Probst, E; von Komorowski, G1
Bangs, CD; Cherry, AM; Frazer, JK; Meeker, ND1
Aricò, M; Barisone, E; Basso, G; Citterio, M; Locatelli, F; Lombardi, A; Micalizzi, C; Nardi, M; Pillon, M; Rondelli, R; Rosolen, A; Testi, AM1
Camitta, BM; Devidas, M; Lauer, SJ; Lu, X; Mahoney, DH; Salzer, WL; Shuster, JJ; Wacker, P; Winick, NJ1
Bain, BJ; Innes, A; May, PC; Pavlů, J1
Ayari, S; Chevallier, P; Delaunay, J; Dumas, PY; Eveillard, M; Guillaume, T; Leguay, T; Lippert, E; Mohty, M; Pigneux, A; Robillard, N1
Kobayashi, R; Matsumoto, Y; Nasu, T; Suzuki, D; Takanashi, K; Uetake, K1
Deguchi, S; Fujii, N; Iwatani, K; Tanimoto, M1
Beck-Popovic, M; Buclin, T; Dao, K; Diezi, M; Ivanyuk, A1
Algara, P; Díaz, MA; Madero, L; Martínez, P; Ramírez, M; Tutor, O1
Dejesus, RS; Hunt, CH; Rao, RD; Swanson, JW; Tefferi, A1
Hynan, L; Kamen, BA; Mantadakis, E; Smith, AK; Winick, NJ1
Centurioni, R; Corvatta, L; Leoni, F; Leoni, P; Malerba, L; Marconi, M; Masia, MC; Mele, A; Offidani, M; Scortechini, A1
Beratis, NG; Eliopoulou, M; Haidas, S; Vlacha, V1
Jaksic, W; Lewis, I; Pozza, C; Veljkovic, D1
Chapman, CS; Szawarski, P1
Conte, ML; Indolfi, P; La Manna, A; Locatelli, F; Nobili, B; Perrotta, S; Rossi, F1
Kanwar, VS; Pearce, J1
Chan, GC; Cheuk, DK; Chiang, AK; Ha, SY; Lau, YL; Shek, TW1
Gottfredsson, M; Steingrímsdóttir, H1
Aebi, C; Leibundgut, K; Ridolfi Lüthy, A; Steiner, I; Wagner, B1
Joseph, M; Layden, BT; Platanias, LC; Tallman, MS1
Pinsk, M; Turner, SR1
Chelstrom, LM; Gunther, R; Myers, DE; Simon, J; Tuel-Ahlgren, L; Uckun, FM1
Bruchelt, G; Carmine, TC; Evans, P; Evans, R; Halliwell, B; Handgretinger, R; Niethammer, D1
Crist, WM; Harris, MB; Krance, RA; Land, VJ; Pinkel, D; Pullen, DJ; Ravindranath, Y; Shuster, JJ1
Gururangan, S; Horner, M; Marina, NM; Rodman, JH1
Miyashita, T; Reed, JC1
Backstrom, L; Boyett, J; Crist, W; Frankel, L; Harris, M; Iyer, R; Land, V; Pullen, J; Shuster, J; van Eys, J1
Dunphy, CH; Kitchen, S; Saravia, O; Velasquez, WS1
Arseniev, L; Bähre, O; Diedrich, H; Kadar, JG; Link, H; Poliwoda, H1
Conter, V; D'Angelo, P; Dampier, C; Jankovic, M; Johnson, FL; Masera, G; Rizzari, C1
Cleary, ML; Davis, RE; Kamel, OW; Soslow, RA; Warnke, RA1
Borowitz, M; Bowman, WP; Buchanan, GR; Farrow, A; Jacaruso, D; Kamen, BA; Shuster, JJ; Winick, N1
Buchholz, B; Eisenbarth, J; Frei, E; Ludwig, R; Weigand, M1
Cardenas-Cardos, R; Gómez-Martínez, R; Leal-Leal, C; Meza-Coria, C; Navarro-Alegría, I; Rivera-Luna, R; Vega-Vega, L1
Bottiglieri, T; Griener, JC; Kamen, BA; Quinn, CT1
Akabutu, JJ; Bernstein, ML; Bowen, T; Camitta, B; Cooley, L; Kamen, BA; Lauer, SJ; Look, AT; Mahoney, DH; Payment, C; Pullen, DJ; Shuster, JJ; Vuchich, MJ; Watson, MS; Whitehead, VM1
Bastard, C; Béné, MC; Callat, MP; Falkenrodt, A; Faure, GC; Garand, R; Kandel, G; Lefranc, MP; Lenormand, B; Lesesve, JF; Maynadié, M; Monconduit, M; Solary, E; Thouret, F; Tilly, H; Vannier, JP1
Camitta, B; Lauer, SJ; Mahoney, DH; Nitschke, R; Shuster, JJ; Steuber, CP; Winick, N1
Hukku, B; Matherly, LH; Pullen, J; Ravindranath, Y; Taub, JW; Williamson, M; Wong, SC; Zhang, L1
Jansen, G; Kaspers, GJ; Mauritz, R; Noordhuis, P; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ1
Akabutu, JJ; Beardsley, GP; Bowen, T; Camitta, B; Cooley, LD; Emami, A; Kamen, BA; Koch, PA; Lauer, SJ; Look, AT; Mahoney, DH; Payment, C; Pullen, DJ; Ravindranath, Y; Shuster, JJ; Vuchich, MJ; Whitehead, VM1
Bueno, J; Julià, A; Villalba, T; Zuazu, J1
Angelides, AG; Gang, DL; Kelleher, JF; Monteleone, PM; Steele, DA1
Camitta, BM; Kiefer, G; Lauer, SJ; Mahoney, DH; Munoz, L; Pullen, JD; Shuster, JJ; Steuber, CP; Toledano, S; Winick, N1
Bernstein, ML; Camitta, B; Cooley, L; Lauer, SJ; Look, AT; Mahoney, DH; Payment, C; Pullen, DJ; Shuster, JJ; Vuchich, MJ; Whitehead, VM1
Botsonis, A; Moschovi, M; Papadopoulou, AL; Tsangaris, GT; Tzortzatou-Stathopoulou, F1
Bökkerink, JP; De Abreu, RA; Lambooy, LH; van Strien, F1
Holowiecki, J; Kachel, L; Lawniczek, T; Pajak, J; Rudzka, E1

Reviews

6 review(s) available for methotrexate and Leukemia, Pre-B-Cell

ArticleYear
Immune Thrombocytopenic Purpura During Maintenance Phase of Acute Lymphoblastic Leukemia: A Rare Coexistence Requiring a High Degree of Suspicion, a Case Report and Review of the Literature.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Dexamethasone; Diagnosis, Differential; Female; Humans; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Platelet Count; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Vincristine

2015
Meta-analysis and meta-regression analysis to compare the outcomes of chemotherapy for T- and B-lineage acute lymphoblastic leukemia (ALL): the use of dexamethasone, L-asparaginase, and/or methotrexate may improve the outcome of T-lineage ALL.
    Annals of hematology, 2016, Volume: 95, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Clinical Trials as Topic; Dexamethasone; Humans; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Regression Analysis; Treatment Outcome

2016
Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:12

    Topics: Acute Kidney Injury; Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Interactions; Gemfibrozil; Hematologic Neoplasms; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors

2008
Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adenoma, Sweat Gland; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Acinar Cell; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Male; Mercaptopurine; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Parotid Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survivors; Sweat Gland Neoplasms; Vincristine; Whole-Body Irradiation

2008
Acute myelofibrosis terminating in acute lymphoblastic leukemia: case report and review of the literature.
    American journal of hematology, 1996, Volume: 51, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 5; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Flow Cytometry; Humans; Immunophenotyping; Male; Mercaptopurine; Methotrexate; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Primary Myelofibrosis; Remission Induction; Vincristine

1996
Low relapse rate in children with acute lymphoblastic leukemia after risk-directed therapy.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Burkitt Lymphoma; Child; Child, Preschool; Combined Modality Therapy; Daunorubicin; Disease-Free Survival; Female; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains; Infant; Leukemia-Lymphoma, Adult T-Cell; Life Tables; Male; Methotrexate; Neoplasm, Residual; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Retrospective Studies; Risk; Survival Analysis; Survival Rate; Treatment Outcome; Vincristine

2001

Trials

20 trial(s) available for methotrexate and Leukemia, Pre-B-Cell

ArticleYear
Results of salvage therapy with mini-hyper-CVD and inotuzumab ozogamicin with or without blinatumomab in pre-B acute lymphoblastic leukemia.
    Journal of hematology & oncology, 2023, 05-02, Volume: 16, Issue:1

    Topics: Adult; Antibodies, Bispecific; Cardiovascular Diseases; Humans; Inotuzumab Ozogamicin; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy

2023
Phase 2 study of hyper-CMAD with liposomal vincristine for patients with newly diagnosed acute lymphoblastic leukemia.
    American journal of hematology, 2020, Volume: 95, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Liposomes; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Rituximab; Survival Rate; Vincristine

2020
Impact of Intrathecal Triple Therapy Versus Intrathecal Methotrexate on Disease-Free Survival for High-Risk B-Lymphoblastic Leukemia: Children's Oncology Group Study AALL1131.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 08-10, Volume: 38, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Dexamethasone; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Nervous System Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone

2020
Neurocognitive Functioning of Children Treated for High-Risk B-Acute Lymphoblastic Leukemia Randomly Assigned to Different Methotrexate and Corticosteroid Treatment Strategies: A Report From the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Aug-10, Volume: 35, Issue:23

    Topics: Adrenal Cortex Hormones; Adult Survivors of Child Adverse Events; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cognition; Dexamethasone; Female; Humans; Insurance, Health; Intelligence; Leucovorin; Male; Medicaid; Memory, Short-Term; Methotrexate; Polyethylene Glycols; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Reaction Time; United States

2017
Cost comparison by treatment arm and center-level variations in cost and inpatient days on the phase III high-risk B acute lymphoblastic leukemia trial AALL0232.
    Cancer medicine, 2018, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cost-Benefit Analysis; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Drug Costs; Female; Follow-Up Studies; Health Expenditures; Hospital Costs; Hospitalization; Humans; Infant; Infant, Newborn; Leucovorin; Male; Methotrexate; Polyethylene Glycols; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Young Adult

2018
Effect of ursodeoxycholic acid and vitamin E in the prevention of liver injury from methotrexate in pediatric leukemia.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018, Volume: 29, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cholagogues and Choleretics; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ursodeoxycholic Acid; Vitamin E; Vitamins

2018
Prediction of outcome by early response in childhood acute lymphoblastic leukemia.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biopsy; Bone Marrow; Cell Lineage; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Patient Outcome Assessment; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Remission Induction; Risk Assessment; Vincristine

2013
Lineage classification of childhood acute lymphoblastic leukemia according to the EGIL recommendations: results of the ALL-BFM 2000 trial.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Lineage; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Immunophenotyping; Infant; Leukemia, Biphenotypic, Acute; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Survival Analysis; Vincristine

2013
Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232.
    Blood, 2015, Aug-20, Volume: 126, Issue:8

    Topics: Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leucovorin; Maintenance Chemotherapy; Male; Methotrexate; Neoplasm, Residual; Polyethylene Glycols; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Proportional Hazards Models; Risk Factors

2015
Dexamethasone and High-Dose Methotrexate Improve Outcome for Children and Young Adults With High-Risk B-Acute Lymphoblastic Leukemia: A Report From Children's Oncology Group Study AALL0232.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 07-10, Volume: 34, Issue:20

    Topics: Adult; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Young Adult

2016
Long-term Results of the Risk-adapted Treatment for Childhood B-Cell Acute Lymphoblastic Leukemia: Report From the Japan Association of Childhood Leukemia Study ALL-97 Trial.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Humans; Hydrocortisone; Infant; Japan; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Risk; Survival Rate; Treatment Outcome; Vincristine

2017
High-dose daunorubicin as liposomal compound (Daunoxome) in elderly patients with acute lymphoblastic leukemia.
    The hematology journal : the official journal of the European Haematology Association, 2003, Volume: 4, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Bone Marrow Diseases; Burkitt Lymphoma; Comorbidity; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Carriers; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, T-Cell; Life Tables; Liposomes; Male; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Safety; Survival Analysis; Topotecan; Treatment Outcome

2003
Correlation of cerebrospinal fluid beta-glucuronidase activity with plasma methotrexate concentrations in leukemic children receiving high-dose methotrexate.
    Pediatric blood & cancer, 2004, Volume: 42, Issue:4

    Topics: Biomarkers; Child; Child, Preschool; Clinical Enzyme Tests; Female; Glucuronidase; Humans; Infant; Inflammation; Linear Models; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2004
Comparison of two schedules of intermediate-dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; United States

1994
Extended triple intrathecal chemotherapy trial for prevention of CNS relapse in good-risk and poor-risk patients with B-progenitor acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Injections, Spinal; Leukemic Infiltration; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Vincristine

1993
Transplantation of allogeneic CD34+ blood cells.
    Blood, 1996, Jun-01, Volume: 87, Issue:11

    Topics: Acute Disease; Adult; Antigens, CD34; Bone Marrow; Cell Division; Cyclosporine; Erythropoietin; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Leukapheresis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Platelet Transfusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; T-Lymphocytes; Transplantation, Homologous

1996
B-lineage acute lymphoblastic leukemia of childhood. An institutional experience.
    Archives of medical research, 1997,Summer, Volume: 28, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Immunophenotyping; Infant; Life Tables; Male; Mercaptopurine; Methotrexate; Neprilysin; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Risk Factors; Survival Analysis; Teniposide; Treatment Outcome; Vincristine

1997
PreB1 (CD10-) acute lymphoblastic leukemia: immunophenotypic and genomic characteristics, clinical features and outcome in 38 adults and 26 children. The Groupe dEtude Immunologique des Leucémies.
    Leukemia & lymphoma, 1998, Volume: 28, Issue:3-4

    Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Preschool; Cortisone; Cyclophosphamide; Daunorubicin; Female; Gene Rearrangement, T-Lymphocyte; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Infant; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Neprilysin; Outcome Assessment, Health Care; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Steroids; Vincristine

1998
Acute neurotoxicity in children with B-precursor acute lymphoid leukemia: an association with intermediate-dose intravenous methotrexate and intrathecal triple therapy--a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:5

    Topics: Acute Disease; Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Infant; Infusions, Intravenous; Injections, Spinal; Leucovorin; Magnetic Resonance Imaging; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Tomography, X-Ray Computed

1998
A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group phase III randomized trial.
    Leukemia, 2001, Volume: 15, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Child, Preschool; Female; Humans; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2001

Other Studies

63 other study(ies) available for methotrexate and Leukemia, Pre-B-Cell

ArticleYear
The Expression and Activation of the NF-κB Pathway Correlate with Methotrexate Resistance and Cell Proliferation in Acute Lymphoblastic Leukemia.
    Genes, 2023, 09-27, Volume: 14, Issue:10

    Topics: Cell Proliferation; Child; Humans; Immunosuppressive Agents; Methotrexate; NF-kappa B; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Necrosis Factor-alpha

2023
Optimizing the use of the hyperCVAD regimen: Clinical vignettes and practical management.
    Cancer, 2020, 03-15, Volume: 126, Issue:6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Constipation; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Monitoring; Fusion Proteins, bcr-abl; Genetic Predisposition to Disease; Humans; Injections, Spinal; Intercellular Signaling Peptides and Proteins; Kidney; Methotrexate; Ophthalmic Solutions; Peripheral Nervous System Diseases; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Protein-Tyrosine Kinases; Vincristine

2020
Double hit B cell precursor leukemia/lymphoma in a patient with a prior diagnosis of follicular lymphoma: a diagnostic and therapeutic dilemma.
    Annals of hematology, 2020, Volume: 99, Issue:2

    Topics: Abnormal Karyotype; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Biopsy; Cyclophosphamide; Disease Progression; DNA Nucleotidylexotransferase; Doxorubicin; Fatal Outcome; Female; Humans; Lymphoma, Follicular; Mercaptopurine; Methotrexate; Middle Aged; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Rituximab; Salvage Therapy; Splenic Rupture; Splenomegaly; Stomach; Vincristine

2020
Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity.
    Cancer medicine, 2020, Volume: 9, Issue:10

    Topics: Acetylcysteine; Bone Marrow; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Deferasirox; Drug Resistance, Neoplasm; Female; Ferric Compounds; Free Radical Scavengers; Humans; Infant; Inhibitory Concentration 50; Iron; Iron Chelating Agents; Male; Methotrexate; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Quaternary Ammonium Compounds; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Transcriptome; Up-Regulation

2020
HSH2D contributes to methotrexate resistance in human T‑cell acute lymphoblastic leukaemia.
    Oncology reports, 2020, Volume: 44, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Line, Tumor; Datasets as Topic; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Humans; Interleukin-2; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

2020
Rare cause of extravasation from implantable venous access device.
    BMJ case reports, 2021, Feb-01, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Catheter-Related Infections; Child, Preschool; Device Removal; Equipment Failure; Extravasation of Diagnostic and Therapeutic Materials; Humans; Maintenance Chemotherapy; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Vascular Access Devices

2021
Impact of Initial CSF Findings on Outcome Among Patients With National Cancer Institute Standard- and High-Risk B-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Aug-01, Volume: 35, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasms; Cerebrospinal Fluid; Child; Clinical Trials as Topic; Cranial Irradiation; Dexamethasone; Disease-Free Survival; Erythrocyte Count; Female; Humans; Leucovorin; Leukocyte Count; Male; Methotrexate; Polyethylene Glycols; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Survival Rate

2017
mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; DNA Damage; Drug Resistance, Neoplasm; Female; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Mercaptopurine; Methotrexate; Mice; Mice, Knockout; Models, Biological; Philadelphia Chromosome; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Xenograft Model Antitumor Assays

2017
Lymphoblastic Lymphoma Involving Multiple Vertebrae.
    World neurosurgery, 2018, Volume: 109

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Spinal Neoplasms; Spine; Young Adult

2018
A successful multidisciplinary approach for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia during pregnancy.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2019, Volume: 35, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Consolidation Chemotherapy; Cryopreservation; Female; Fertility Preservation; Fetal Growth Retardation; Humans; Induction Chemotherapy; Infant, Newborn; Male; Methotrexate; Ovariectomy; Ovary; Patient Care Team; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Neoplastic

2019
The association between fasting hypoglycemia and methylated mercaptopurine metabolites in children with acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Blood Glucose; Child; Child, Preschool; Dexamethasone; Dietary Carbohydrates; Drug Administration Schedule; Fasting; Female; Guanine Nucleotides; Humans; Hyperglycemia; Hypoglycemia; Hypoxanthine Phosphoribosyltransferase; Infant; Liver Glycogen; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Methylation; Methyltransferases; Polymorphism, Genetic; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prodrugs; Retrospective Studies; Thionucleotides

2014
Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.
    Experimental hematology, 2015, Volume: 43, Issue:1

    Topics: Animals; Antineoplastic Agents; Biopsy; Clone Cells; Cytarabine; Deoxycytidine Kinase; Dexamethasone; Disease Progression; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Gene Dosage; Heterografts; Humans; Male; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Proteins; Neoplasm Transplantation; Neoplastic Stem Cells; Peptide Synthases; Polymorphism, Single Nucleotide; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Radiation Chimera; Sequence Analysis, DNA; Vincristine

2015
Dysplastic bone marrow changes during maintenance therapy for acute leukemia.
    Journal of pediatric hematology/oncology, 2015, Volume: 37, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Disease Management; Female; Follow-Up Studies; Humans; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prognosis

2015
Single agent blinatumumab as frontline therapy for an 85-year-old patient with B cell precursor acute lymphoblastic leukemia.
    Annals of hematology, 2016, Volume: 95, Issue:11

    Topics: Aged, 80 and over; Antibodies, Bispecific; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carcinoma, Transitional Cell; Cytarabine; Female; Humans; Lymphoma, B-Cell; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Salvage Therapy; Urinary Bladder Neoplasms; Vincristine

2016
Evaluation and Management of Acute-Onset Hemiparesis in an Adolescent With Leukemia.
    Pediatric emergency care, 2018, Volume: 34, Issue:3

    Topics: Adolescent; Antidotes; Antimetabolites, Antineoplastic; Brain; Diffusion Magnetic Resonance Imaging; Humans; Leucovorin; Male; Methotrexate; Neurotoxicity Syndromes; Paresis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2018
Histiocytic sarcoma: secondary neoplasm or "transdifferentiation" in the setting of B-acute lymphoblastic leukemia.
    Blood, 2016, 11-17, Volume: 128, Issue:20

    Topics: Adult; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Female; GTP Phosphohydrolases; Histiocytic Sarcoma; Humans; Membrane Proteins; Mercaptopurine; Methotrexate; Mutation, Missense; Neoplasms, Second Primary; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tumor Suppressor Protein p53; Vincristine

2016
Nonfunctioning Adrenocortical Carcinoma in Pediatric Acute Lymphoblastic Leukemia: A Case Report of a Rare Multiple Primaries Combination.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Doxorubicin; Etoposide; Fatal Outcome; Humans; Language Development Disorders; Lung Neoplasms; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Nephrectomy; Pneumonectomy; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2017
A Stroke Mimic: A 14-Year-Old Cancer Patient Presenting With Acute Right-Sided Weakness.
    Pediatric emergency care, 2017, Volume: 33, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Diagnosis, Differential; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Paresis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Stroke

2017
Extremely slow methotrexate elimination in a patient with t(9;22) positive acute lymphoblastic leukemia treated with imatinib.
    American journal of hematology, 2008, Volume: 83, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Drug Interactions; Edema; Etoposide; Female; Humans; Imatinib Mesylate; Leucovorin; Methotrexate; Middle Aged; Piperazines; Pleural Effusion, Malignant; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Sodium Potassium Chloride Symporter Inhibitors; Translocation, Genetic

2008
Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia.
    Blood, 2009, Jun-18, Volume: 113, Issue:25

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cranial Irradiation; Cyclophosphamide; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Proportional Hazards Models; Remission Induction; Vincristine; Young Adult

2009
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Charcot-Marie-Tooth Disease; Contraindications; Cytarabine; Daunorubicin; Etoposide; Gait Disorders, Neurologic; Humans; Male; Mercaptopurine; Methotrexate; Muscle Weakness; Neural Conduction; Peripheral Nervous System Diseases; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine

2008
Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy
    Cancer, 2009, May-15, Volume: 115, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Treatment Outcome; Vincristine

2009
Delayed recognition of intrathecal methotrexate overdose.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Child; Cytarabine; Drug Overdose; Female; Humans; Injections, Spinal; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone

2009
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct end
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:1

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Daunorubicin; Endothelium, Vascular; Epilepsy, Tonic-Clonic; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Injections, Spinal; Leukoencephalopathies; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Sinus Thrombosis, Intracranial; Vincristine

2010
The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse.
    Leukemia, 2010, Volume: 24, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Female; Humans; Infant; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Methyltransferases; Neoplasm Recurrence, Local; Neutrophils; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Survival Rate; Treatment Outcome

2010
[Hemiparesis in acute lymphoblastic leukemia].
    Der Radiologe, 2010, Volume: 50, Issue:8

    Topics: Adolescent; Antimetabolites, Antineoplastic; Brain; Cytarabine; Diffusion Magnetic Resonance Imaging; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Injections, Spinal; Methotrexate; Neurologic Examination; Neurotoxicity Syndromes; Paresis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2010
A pediatric B lineage leukemia with coincident MYC and MLL translocations.
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Flow Cytometry; Histone-Lysine N-Methyltransferase; Humans; Male; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proto-Oncogene Proteins c-myc; Translocation, Genetic; Vincristine

2011
Long-term results of AIEOP-8805 protocol for acute B-cell lymphoblastic leukemia of childhood.
    Pediatric blood & cancer, 2011, Volume: 56, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine

2011
Plasma methotrexate, red blood cell methotrexate, and red blood cell folate values and outcome in children with precursor B-acute lymphoblastic leukemia: a report from the Children's Oncology Group.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Humans; Infant; Male; Methotrexate; Polymorphism, Single Nucleotide; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Prospective Studies

2012
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine

2012
Rituximab for the treatment of adult relapsed/refractory CD20 positive B-ALL patients: a pilot series.
    Leukemia research, 2012, Volume: 36, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Pilot Projects; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Risk Factors; Rituximab; Salvage Therapy; Survival Rate; Vincristine; Young Adult

2012
Retinitis from cytomegalovirus during maintenance treatment for acute lymphoblastic leukemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antiviral Agents; Child; Cytomegalovirus Retinitis; Drug Therapy, Combination; Foscarnet; Humans; Immunocompromised Host; Immunosuppressive Agents; L-Lactate Dehydrogenase; Lymphohistiocytosis, Hemophagocytic; Male; Methotrexate; Methylprednisolone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Retinal Detachment; Vincristine

2012
Subacute methotrexate-related leukoencephalopathy with stroke-like presentation.
    International journal of hematology, 2012, Volume: 96, Issue:6

    Topics: Antimetabolites, Antineoplastic; Brain Ischemia; Cytarabine; Deglutition Disorders; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Doxorubicin; Dysarthria; Hemiplegia; Humans; Hydrocortisone; Injections; Leukoencephalopathies; Magnetic Resonance Angiography; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Young Adult

2012
Pharmacokinetic interaction between methotrexate and chloral hydrate.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:3

    Topics: Antineoplastic Agents; Child, Preschool; Chloral Hydrate; Drug Interactions; Female; Humans; Hypnotics and Sedatives; Injections, Spinal; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2013
Loss of heterozygosity of p16 correlates with minimal residual disease at the end of the induction therapy in non-high risk childhood B-cell precursor acute lymphoblastic leukemia.
    Leukemia research, 2002, Volume: 26, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p16; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Deletion; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor; Genes, p16; Humans; Infant; Life Tables; Loss of Heterozygosity; Male; Mercaptopurine; Methotrexate; Microsatellite Repeats; Neoplasm, Residual; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome; Vincristine

2002
Methotrexate induced seizures associated with acute reversible magnetic resonance imaging (MRI) changes in a patient with acute lymphoblastic leukemia.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:6

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Daunorubicin; Epilepsy, Tonic-Clonic; Female; Humans; Injections, Intravenous; Injections, Spinal; Magnetic Resonance Imaging; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine

2002
Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:8

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Female; Humans; Hydrocortisone; Injections, Spinal; Karyotyping; Leucovorin; Life Tables; Lymphocytes; Male; Mercaptopurine; Methotrexate; Neoplastic Stem Cells; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pteroylpolyglutamic Acids; Recurrence; Remission Induction; Survival Analysis; Tumor Cells, Cultured; Vincristine

2002
Methotrexate-induced leukoencephalopathy reversed by aminophylline and high-dose folinic acid.
    Acta haematologica, 2004, Volume: 111, Issue:4

    Topics: Adult; Aminophylline; Brain Diseases; Female; Humans; Leucovorin; Magnetic Resonance Imaging; Methotrexate; Neurotoxicity Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2004
A woman who couldn't speak: report of methotrexate neurotoxicity.
    Postgraduate medical journal, 2005, Volume: 81, Issue:953

    Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Female; Humans; Methotrexate; Neurotoxicity Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Speech Disorders

2005
Membranous glomerulopathy in children given allogeneic hematopoietic stem cell transplantation.
    Haematologica, 2005, Volume: 90 Suppl

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Edema; Glomerulonephritis, Membranous; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Transplantation Conditioning; Transplantation, Homologous; Vincristine

2005
Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Migraine Disorders; Oxazolidinones; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Serotonin Receptor Agonists; Tryptamines

2007
Disseminated invasive aspergillosis in a patient with acute leukaemia.
    Acta bio-medica : Atenei Parmensis, 2006, Volume: 77 Suppl 2

    Topics: Acute Kidney Injury; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Bacteremia; Caspofungin; Chlamydophila Infections; Chlamydophila pneumoniae; Doxorubicin; Drug Resistance, Multiple, Fungal; Drug Therapy, Combination; Echinocandins; Fatal Outcome; Female; Humans; Immunocompromised Host; Lipopeptides; Liposomes; Lung Diseases, Fungal; Medical Futility; Methotrexate; Middle Aged; Neuroaspergillosis; Peptides, Cyclic; Pneumonia, Bacterial; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Streptococcal Infections; Triazoles; Vincristine; Voriconazole

2006
Fatal adenovirus hepatitis during maintenance therapy for childhood acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adenovirus Infections, Human; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Asparaginase; Child, Preschool; Cidofovir; Computer Systems; Cytosine; DNA, Viral; Fatal Outcome; Hepatitis, Viral, Human; Humans; Immunocompromised Host; Male; Mercaptopurine; Methotrexate; Multiple Organ Failure; Organophosphonates; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine; Viremia

2008
Acute lymphoblastic leukemia in a patient with chronic cyanoacrylate exposure.
    Acta haematologica, 2007, Volume: 118, Issue:4

    Topics: Adhesives; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyanoacrylates; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Humans; Male; Mercaptopurine; Methotrexate; Mouth Mucosa; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Salvage Therapy; Self Care; Tooth Fractures; Vincristine

2007
Ondansetron-associated hypokalemia in a 2-year-old with pre-B-cell ALL.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:1

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cytarabine; Dexamethasone; Female; Humans; Hypokalemia; Mercaptopurine; Methotrexate; Nausea; Ondansetron; Polyethylene Glycols; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Vincristine

2008
Biotherapy for xenografted human central nervous system leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19)-pokeweed antiviral protein immunotoxin.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Blood-Brain Barrier; Bone Marrow; Cell Movement; Central Nervous System; DNA, Neoplasm; Drug Evaluation, Preclinical; Immunotoxins; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Leukemic Infiltration; Meninges; Methotrexate; Mice; Mice, SCID; N-Glycosyl Hydrolases; Neoplasm Transplantation; Neoplastic Cells, Circulating; Plant Proteins; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribosome Inactivating Proteins, Type 1; Specific Pathogen-Free Organisms; Transplantation, Heterologous

1995
Presence of iron catalytic for free radical reactions in patients undergoing chemotherapy: implications for therapeutic management.
    Cancer letters, 1995, Aug-01, Volume: 94, Issue:2

    Topics: Adolescent; Bleomycin; Burkitt Lymphoma; Child; Child, Preschool; Female; Humans; Infant; Iron; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies

1995
Successful treatment of acute lymphoblastic leukemia in a child with cystic fibrosis.
    Medical and pediatric oncology, 1994, Volume: 22, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cystic Fibrosis; Cytarabine; Daunorubicin; Female; Humans; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Teniposide; Vincristine

1994
Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line.
    Blood, 1993, Jan-01, Volume: 81, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cell Survival; Dexamethasone; DNA, Neoplasm; Flow Cytometry; Humans; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transfection; Tumor Cells, Cultured

1993
High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1996, Volume: 17, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Down Syndrome; Fatal Outcome; Graft vs Host Disease; Humans; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Salvage Therapy; Transplantation, Homologous; Vincristine; Whole-Body Irradiation

1996
True histiocytic lymphoma following therapy for lymphoblastic neoplasms.
    Blood, 1996, Jun-15, Volume: 87, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasms, Second Primary; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Remission Induction; Scapula; Spinal Neoplasms; Vincristine

1996
Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:10

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

1996
Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:12

    Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphocytes; Male; Methotrexate; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1996
Methotrexate, homocysteine, and seizures.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Epilepsy, Tonic-Clonic; Homocysteine; Humans; Infant; Male; Methotrexate; Neurotransmitter Agents; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1998
Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosomes, Human, Pair 12; DNA-Binding Proteins; ETS Translocation Variant 6 Protein; Female; Humans; Infant; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-ets; Repressor Proteins; Transcription Factors; Translocation, Genetic

1998
Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Adolescent; Amino Acid Sequence; Antimetabolites, Antineoplastic; Carrier Proteins; Child; Child, Preschool; Female; Gene Expression; Humans; Immunophenotyping; Infant; K562 Cells; Leukemia, T-Cell; Male; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Molecular Sequence Data; Ploidies; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; Tritium; Tumor Cells, Cultured

1998
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Blood, 1999, Feb-01, Volume: 93, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; HL-60 Cells; Humans; Infant; Infant, Newborn; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; U937 Cells

1999
Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6

    Topics: Adolescent; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 4; Female; Folic Acid; Humans; Male; Methotrexate; Neoplastic Stem Cells; Peptide Synthases; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Trisomy

1998
[Acute leukemia in Jehovah's Witnesses].
    Sangre, 1999, Volume: 44, Issue:5

    Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion; Christianity; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Fatal Outcome; Female; Humans; Male; Mercaptopurine; Methotrexate; Personnel, Hospital; Physician-Patient Relations; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Refusal to Treat; Remission Induction; Right to Die; Treatment Refusal; Vincristine

1999
Hepatic dysfunction as the presenting feature of acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biopsy; Child, Preschool; Cholestasis, Intrahepatic; Chromosome Deletion; Daunorubicin; Hepatomegaly; Humans; Liver; Liver Function Tests; Male; Mercaptopurine; Methotrexate; Practice Guidelines as Topic; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Thrombocytopenia; Ultrasonography; Vincristine

2001
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Leukemia, 2001, Volume: 15, Issue:7

    Topics: Child; Child, Preschool; Core Binding Factor Alpha 2 Subunit; Female; Humans; Infant; Lymphocytes; Male; Methotrexate; Oncogene Proteins, Fusion; Ploidies; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic

2001
Synergistic interaction of methotrexate and 6-mercaptopurine in human derived malignant T-ALL and CALLA+ cell lines.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Carbon Radioisotopes; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Drug Synergism; Glycine; Humans; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Mercaptopurine; Methotrexate; Phosphates; Phosphorus Radioisotopes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Purines; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate

1991
Skin manifestation of extramedullary relapse in adult with acute lymphoblastic leukaemia.
    Haematologia, 1991, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Immunotherapy; Leukemic Infiltration; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Radiotherapy; Recurrence; Remission Induction; Skin; Vincristine

1991