methotrexate has been researched along with Laryngeal Neoplasms in 88 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 67 (76.14) | 18.7374 |
1990's | 13 (14.77) | 18.2507 |
2000's | 3 (3.41) | 29.6817 |
2010's | 4 (4.55) | 24.3611 |
2020's | 1 (1.14) | 2.80 |
Authors | Studies |
---|---|
Jain, D; Panda, S; Rajeshwari, M; Sakthivel, P; Singh, CA; Yogal, R | 1 |
Caldas, HC; Castro, R; Galbiatti, AL; Goloni-Bertollo, EM; Padovani, JA; Pavarino, EC | 1 |
Alcocer, S; Bohorquez, D; de Morales, TR; Morón-Medina, A; Viera, N | 1 |
Bartolomeu, AR; da Silva, LM; de Oliveira, DE; Frión-Herrera, Y; Romagnoli, GG; Sforcin, JM | 1 |
Caldas, HC; Galbiatti, AL; Goloni-Bertollo, EM; Padovani, JA; Pavarino, EC | 1 |
DONOHUE, DM; FOYE, LV; JACOBS, EM; PAPAC, RJ | 1 |
FREEMAN, RG; KNOX, JM; ROSSMAN, RE | 1 |
JOHNSON, NE; SISSON, GA | 1 |
MAGUDA, TA; WATSON, DR | 1 |
O'KEEFE, JJ; WEISS, AJ | 1 |
Freeland, AP; Patiar, S; Ramsden, JD | 1 |
Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Nishimura, G; Taguchi, T; Tsukuda, M; Yoshida, T | 1 |
Cacev, T; Kralj, M; Kraljevic Pavelic, S | 1 |
Daly, JF; Friedman, M | 1 |
Bertino, JR; Lefkowitz, E; Papac, R | 1 |
Beutter, P; Brasnu, D; Dulmet-Brender, E; Jaubert, F; Renault, P | 1 |
Beutter, P; Brasnu, D; Chabolle, F; de Braquilanges, E; Laccourreye, H; Strunski, W | 1 |
Bassot, V; Beutter, P; Brasnu, D; Garabedian, N; Jacquillat, C; Lacau-Saint-Guily, J; Laccourreye, H | 1 |
Bobba, L; Bottoni, P; Croce, M; Provera, F; Ranieri, MG; Zaietta, P | 1 |
Kessler, E; Laurian, N; Sadov, R; Strauss, M | 1 |
Ervin, TJ; Fabian, RL; Miller, D; Norris, CM; Posner, MR; Rose, C; Weichselbaum, RR | 1 |
Baĭmakanova, SSh; Borisevich, NV | 1 |
Reay-Young, P | 1 |
Kuśnierczyk, W; Namyslowski, G; Singer, Z; Swierczyński, Z; Swierczyśka, B; Wróbel, M | 1 |
Fazekas, JT; Kramer, S; Sommer, C | 1 |
Avidano, MA; Singleton, GT | 1 |
Allegra, CJ; Chu, E; Copur, S; Dahut, W | 1 |
Hall, SW; Miercort, RD | 1 |
Beketić-Oresković, L; Matulić, M; Osmak, M; Sorić, J | 1 |
Israel, HL; Kane, GC; Peters, SP; Troshinsky, MB | 1 |
Korzeniowski, S; Sas-Korczyńska, B; Skolyszewski, J | 1 |
Daly, M; Harden, P; Knepil, J; Symonds, P; Thomson, AH | 1 |
Bahadur, S; Ranganathan, A; Rath, GK; Tandon, DA; Thakar, A | 1 |
Amonkar, AJ; D'cruz, AK; Juvekar, AS; Pradhan, S; Saikaia, T | 1 |
Calvert, AH; Hill, BT; Hughes, KB; Price, LA; Shaw, HJ | 1 |
DeWys, WD | 1 |
Bertino, JR | 1 |
Carter, SK; Goldsmith, MA | 1 |
Caudry, M; Caudry, Y; Dabadie, P; Dilhuydy, JM; Michelet, FX; Pinsolle, J; Ragot, C; Reboul, J | 1 |
Bouchelle, WH; Chretien, PB; Elias, EG; Hande, KR; Khan, T; Lipson, SD; Monnard, E; Wiernik, PH; Zentai, T | 1 |
Bitran, JD; Matz, G; Toledo-Pereyra, LH | 1 |
Reich, SD | 1 |
Bobrow, S; Fischer, JJ; Knowlton, AH; Percarpio, B | 1 |
Manni, JJ; Van den Broek, P | 1 |
Kramer, S | 2 |
Bergman, JA; Biller, HF | 1 |
Iachmeneva, NF; Medvedev, ES; Vtiurin, BM | 1 |
Osmak, M | 1 |
Vakaet, L; van Eijkeren, M | 1 |
Levine, PA; Tabbara, IA | 1 |
Andreev, VG; Filippov, KG; Kurpeshev, OK; Lopatin, VF; Mardynskiĭ, IuS; Shaimbetov, BO | 1 |
Barron, P; Cripps, C; Danjoux, C; de la Bastide, Y; Hardie, J; Nichol, J; Odell, P | 1 |
Byhardt, RW; Cox, JD; Duncavage, JA; Grossman, TW; Hoffmann, RG; Holoye, PY; Kun, LE; Malin, T; Ritch, PS; Toohill, RJ | 1 |
Nagel, GA; Scherpe, A; Schröder, M; von Heyden, HW | 1 |
Cohen, Y; Kuten, A; Robinson, E; Zidan, J | 1 |
Bassot, V; Bonfils, P; Brasnu, D; Fabre, A; Janot, F; Laccourreye, H; Ménard, M | 1 |
Bassot, V; Brasnu, D; Fabre, A; Janot, F; Laccourreye, H; Ménard, M | 1 |
Clifford, P; Grant, HR | 1 |
Colon, J; Mayer, M | 1 |
Donegan, WL; Harris, HS | 1 |
Gary-Bobo, J | 1 |
Shaw, HJ | 1 |
Alberto, P; Broquet, MA; Jacot-Descombe, E; Montandon, A | 1 |
Leroux-Robert, J | 1 |
Albala, MM; Leone, LA; Rege, VB | 1 |
Bertino, JR; Capizzi, RL; DeConti, RC; Marsh, JC | 1 |
Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP | 1 |
Bertino, JR; DeConti, RC; Kaplan, SR; Mitchell, MS; Papac, R; Wawro, NW | 1 |
Foley, JF; Lemon, HM; Miller, D | 1 |
Auboyer, C; Bonnafous, N; Cheix-Servonnat, F; Pommatau, E | 1 |
Williams, RG | 1 |
Danko, T; Klimo, J | 1 |
Hardingham, M; Hulbert, MH; Walsh-Waring, GP | 1 |
Freckman, HA | 1 |
Adler, GF; Hagan, B; Indyk, JS; Reay-Young, PS | 1 |
Priestman, TJ | 1 |
Donaldson, RC | 2 |
Chahinian, P; Depierre, A; Israel, L | 1 |
Elliott, RD; Montgomery, JA; Straight, SL; Temple, C | 1 |
Kagan, AR | 1 |
Daly, JF; DeNarvaes, FN; Friedman, M | 1 |
Constable, WC; Fitz-Hugh, GS; Marks, RD; Robbins, JP | 1 |
Healy, JB; Maddock, PG; Moriarty, MJ | 1 |
Liubaev, VL; Poliakov, BI | 1 |
Lane, M; Levin, H; Moore, JE; Smith, FE | 1 |
Kadlecová, D; Konecný, M; Mechl, Z | 1 |
6 review(s) available for methotrexate and Laryngeal Neoplasms
Article | Year |
---|---|
B-cell lymphoma of the larynx in a patient with rheumatoid arthritis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclophosphamide; Doxorubicin; Humans; Laryngeal Neoplasms; Lymphoma, B-Cell; Male; Methotrexate; Prednisone; Tomography, X-Ray Computed; Vincristine | 2005 |
Adjuvant drug strategies in the treatment of recurrent respiratory papillomatosis.
Topics: Adolescent; Adult; Age of Onset; Aged; Chemotherapy, Adjuvant; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Interferons; Isotretinoin; Laryngeal Neoplasms; Laser Therapy; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Papilloma; Remission Induction; Retrospective Studies; Tracheal Neoplasms | 1995 |
Pneumocystis carinii pneumonia associated with weekly methotrexate: cumulative dose of methotrexate and low CD4 cell count may predict this complication.
Topics: Carcinoma, Squamous Cell; CD4-CD8 Ratio; Drug Administration Schedule; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Male; Methotrexate; Methylprednisolone; Middle Aged; Pneumonia, Pneumocystis | 1993 |
Current concepts of chemotherapy combined with other modalities for head and neck cancer.
Topics: Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Immunotherapy; Laryngeal Neoplasms; Leucovorin; Methotrexate; Neoplasm Metastasis; Neoplasms; Radiotherapy; Vinblastine | 1975 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Leucovorin; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Tongue Neoplasms | 1975 |
The role of chemotherapy in the management of advanced laryngeal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Humans; Laryngeal Neoplasms; Methotrexate | 1992 |
9 trial(s) available for methotrexate and Laryngeal Neoplasms
Article | Year |
---|---|
[Comparative study of 2 chemotherapy induction protocols. Cisplatinum-methotrexate-bleomycin and oncovin-methotrexate-bleomycin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Staging; Pharyngeal Neoplasms; Prospective Studies; Random Allocation; Vincristine | 1983 |
Critique of "adjuvant intravenous methotrexate of definitive radiotherapy alone for advanced squamous cancers of the oral cavity, oropharynx, supraglottic larynx or hypopharynx. Concluding report of an RTOG randomized trial on 638 patients".
Topics: Carcinoma, Squamous Cell; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms | 1981 |
Laryngeal preservation by treatment with induction chemotherapy and radiotherapy protocol for stage III & IV carcinoma larynx--results of a pilot study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin; Fluorouracil; Humans; Laryngeal Neoplasms; Laryngectomy; Male; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Survival Rate | 1999 |
Chemotherapy prior to local therapy in advanced squamous cell carcinoma of the head and neck: Preliminary assessment of an intensive drug regimen.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms | 1979 |
Methotrexate and radiation therapy in the treatment of advanced head and neck tumors.
Topics: Carcinoma, Squamous Cell; Connecticut; Epiglottis; Head and Neck Neoplasms; Humans; Iridium; Laryngeal Neoplasms; Methotrexate; Mouth Floor; Pharyngeal Neoplasms; Radioisotopes; Radiotherapy Dosage; Radiotherapy, High-Energy; Tongue Neoplasms; Tonsillar Neoplasms | 1975 |
Small-cell carcinoma of the head and neck. A novel treatment regimen.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Evaluation; Etoposide; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Radiotherapy Dosage; Remission Induction; Tongue Neoplasms; Vincristine | 1991 |
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Time Factors | 1986 |
Low dosage methotrexate (NSC-740) and cyclophosphamide (NSC 26271) for solid tumors.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Cyclophosphamide; Drug Combinations; Female; Humans; Laryngeal Neoplasms; Lung Neoplasms; Male; Melanoma; Methotrexate; Middle Aged; Nausea; Neoplasms; Radiography; Rectal Neoplasms; Stomatitis; Wilms Tumor | 1970 |
Combination chemotherapy for 418 cases of advanced cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Drug Synergism; Female; Fluorouracil; History, 16th Century; Humans; Hydrazines; Injections, Intravenous; Laryngeal Neoplasms; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Neoplasms; Prognosis; Time Factors; Tongue Neoplasms; Vinblastine | 1971 |
73 other study(ies) available for methotrexate and Laryngeal Neoplasms
Article | Year |
---|---|
Composite tumor of the larynx: A Case Report.
Topics: Administration, Metronomic; Carcinoma, Neuroendocrine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatal Outcome; Humans; Laryngeal Neoplasms; Larynx; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Complex and Mixed; Palliative Care; Positron-Emission Tomography; Tracheostomy | 2020 |
Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Laryngeal Neoplasms; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Transcriptome | 2013 |
[Methotrexate as inducer of proinflammatory cytokines by epithelial cells].
Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Laryngeal Neoplasms; Methotrexate; Stomatitis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bees; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Doxorubicin; Drug Therapy, Combination; Humans; L-Lactate Dehydrogenase; Laryngeal Neoplasms; Methotrexate; Propolis; Verapamil | 2016 |
Sensitivity of human laryngeal squamous cell carcinoma Hep-2 to metrotexate chemoterapy.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Laryngeal Neoplasms; Methotrexate | 2012 |
SYSTEMIC THERAPY WITH AMETHOPTERIN IN SQUAMOUS CARCINOMA OF THE HEAD AND NECK.
Topics: Bone Marrow Examination; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Humans; Injections, Intravenous; Laryngeal Neoplasms; Leukopenia; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Stomatitis; Tongue Neoplasms; Tonsillar Neoplasms; Toxicology | 1963 |
MULTIPLE KERATOACANTHOMAS. A CASE STUDY OF THE ERUPTIVE TYPE WITH OBSERVATIONS ON PATHOGENESIS.
Topics: Aminopterin; Black People; Carcinoma; Carcinoma, Squamous Cell; Diagnosis, Differential; Foot Diseases; Hand Dermatoses; Histocytochemistry; Humans; Keratoacanthoma; Laryngeal Neoplasms; Methotrexate; Neoplasms; Pathology; Ultraviolet Rays | 1964 |
CARCINOMA OF THE LARYNX--REVIEW OF 100 CASES.
Topics: Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Classification; Electronic Data Processing; Hoarseness; Humans; Laryngeal Neoplasms; Laryngectomy; Larynx; Methotrexate; Neck Dissection; Neoplasm Metastasis; Neoplasms; Pathology; Radiography; Radioisotope Teletherapy; Speech Therapy; Toxicology | 1964 |
TECHNIC AND TREATMENT OF TUMORS OF THE HEAD AND NECK BY TEMPORAL ARTERY INFUSION.
Topics: Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Leucovorin; Maxillary Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms; Orbital Neoplasms; Palatal Neoplasms; Temporal Arteries; Tongue Neoplasms; Toxicology | 1964 |
ADJUVANT TUMOR CHEMOTHERAPY IN ADVANCED HEAD AND NECK CANCER.
Topics: Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Glossectomy; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate; Neck Dissection; Neoplasms; Pathology; Pharyngeal Neoplasms; Tongue Neoplasms | 1965 |
Concurrent chemoradiotherapy with cisplatin, 5-fluorouracil, methotrexate, and leucovorin in patients with advanced resectable squamous cell carcinoma of the larynx and hypopharynx.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Humans; Hypopharynx; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vitamin B Complex | 2006 |
A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate.
Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Laryngeal Neoplasms; Methotrexate; Polymerase Chain Reaction | 2008 |
The treatment of squamous cell carcinoma of the head and neck with methotrexate and irradiation.
Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1967 |
Methotrexate (NSC-740) in squamous cell carcinoma of the head and neck. II. Intermittent intravenous therapy.
Topics: Carcinoma, Squamous Cell; Humans; Laryngeal Neoplasms; Male; Methotrexate; Pharyngeal Neoplasms; Tongue Neoplasms | 1967 |
[Carcinoma of the upper respiratory and digestive tracts. Histopathology and chemotherapy in 300 cases (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate; Pharyngeal Neoplasms; Preoperative Care; Vincristine | 1981 |
[Preliminary results of a preoperative polychemotherapy protocol in carcinomas of the pharyngo-larynx. Oncovin, methotrexate and bleomycin (author's transl)].
Topics: Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Pharyngeal Neoplasms; Preoperative Care; Retrospective Studies; Vincristine | 1981 |
[Asymptomatic electrocardiographic abnormalities during antiblastic chemotherapy].
Topics: Aged; Antineoplastic Agents; Arrhythmias, Cardiac; Breast Neoplasms; Cardiac Complexes, Premature; Cyclophosphamide; Electrocardiography; Esophageal Neoplasms; Female; Fluorouracil; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tamoxifen; Vincristine | 1983 |
Laryngeal carcinoma in childhood. Report of a case and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Child; Cisplatin; Cyclophosphamide; Humans; Laryngeal Neoplasms; Laryngoscopy; Male; Methotrexate; Radiotherapy Dosage | 1984 |
The role of chemotherapy for advanced carcinoma of the supraglottic and glottic larynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Glottis; Humans; Laryngeal Neoplasms; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Palliative Care; Platinum | 1984 |
[Effectiveness of radiotherapy and chemoradiotherapy of disseminated laryngeal cancer].
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Gamma Rays; Humans; Laryngeal Neoplasms; Methotrexate | 1984 |
[Immunochemotherapy in cases of advanced laryngeal cancer].
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Remission, Spontaneous | 1981 |
Adjuvant intravenous methotrexate or definitive radiotherapy alone for advanced squamous cancers of the oral cavity, oropharynx, supraglottic larynx or hypopharynx.
Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Oropharynx; Pharyngeal Neoplasms; Prognosis; Random Allocation | 1980 |
Bone marrow aplasia and severe skin rash after a single low dose of methotrexate.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Eruptions; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Pancytopenia | 1995 |
Chemotherapy and radiation therapy for laryngeal cancer.
Topics: Antineoplastic Agents; Bleomycin; Cisplatin; Drug Combinations; Fluorouracil; Humans; Laryngeal Neoplasms; Larynx; Methotrexate; Neoplasm Staging; Radiation Dosage; Treatment Outcome | 1995 |
Resistance of human larynx carcinoma cells to cisplatin, gamma-irradiation and methotrexate does not involve overexpression of c-myc or c-Ki-ras oncogenes.
Topics: Blotting, Northern; Cell Survival; Cisplatin; Drug Resistance; Gamma Rays; Gene Expression; Genes, myc; Genes, ras; Humans; Laryngeal Neoplasms; Methotrexate; RNA, Neoplasm; Tumor Cells, Cultured; Vincristine | 1993 |
Results of treatment of inoperable recurrences of laryngeal cancer after total laryngectomy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Disease-Free Survival; Humans; Laryngeal Neoplasms; Laryngectomy; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neutrons; Radiotherapy Dosage; Time Factors; Vincristine | 1996 |
Methotrexate removal during haemodialysis in a patient with advanced laryngeal carcinoma.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Carcinoma, Squamous Cell; Fatal Outcome; Humans; Infusions, Parenteral; Injections, Intravenous; Kidney Failure, Chronic; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Palliative Care; Renal Dialysis; Terminal Care | 1996 |
Chemosensitivity of advanced larynx carcinoma cells in vitro and significance of multidrug resistance markers in these tumors.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Cell Survival; Cisplatin; Drug Resistance, Multiple; Fluorouracil; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Mitomycin; Neoplasm Metastasis; Neoplasm Staging; Protein Kinase C; Tumor Cells, Cultured | 1998 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Laryngeal Neoplasms; Maxillary Neoplasms; Mercaptopurine; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms; Vincristine | 1975 |
Chemotherapeutic approaches to advanced carcinoma of the larynx.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Methotrexate | 1975 |
[The combination of radiotherapy and polychemotherapy in the treatment of advanced carcinomas of the upper respiratory digestive tract (author's transl)].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Radioisotope Teletherapy; Tongue Neoplasms; Tonsillar Neoplasms | 1977 |
Oat cell carcinoma of the larynx: response to combined modality therapy.
Topics: Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Humans; Laryngeal Neoplasms; Leucovorin; Lymphatic Metastasis; Male; Methotrexate; Neck; Radiotherapy Dosage; Remission, Spontaneous | 1978 |
Mathematical modeling -- guide to high-dose methotrexate infusion therapy.
Topics: Carcinoma, Squamous Cell; Humans; Kinetics; Laryngeal Neoplasms; Methotrexate; Models, Biological; Neoplasm Metastasis; Neoplasms; Sarcoma, Ewing | 1979 |
Pulmonary complications of methotrexate therapy.
Topics: Carcinoma, Squamous Cell; Glottis; Humans; Laryngeal Neoplasms; Laryngectomy; Lymphangitis; Male; Mandibular Neoplasms; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pulmonary Fibrosis; Radiotherapy Dosage | 1977 |
Methotrexate and radiation therapy in the treatment of advanced squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, and hypopharynx. (Preliminary report of a controlled clinical trial of the Radiation Therapy Oncology Group).
Topics: Administration, Oral; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; United States | 1975 |
Verrucous carcinoma of the larynx.
Topics: Biopsy; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diagnosis, Differential; Humans; Laryngeal Neoplasms; Laryngectomy; Methotrexate | 1975 |
[Treatment of cancer metastases in the lymph nodes of the neck in undiagnosed primary tumor].
Topics: Adult; Aged; Evaluation Studies as Topic; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Radiotherapy Dosage; Retroperitoneal Neoplasms; Stomach Neoplasms | 1976 |
Collateral resistance or sensitivity of human larynx carcinoma HEp2 cells resistant to cis-dichlorodiammineplatinum (II) or vincristine sulfate.
Topics: Cell Survival; Cisplatin; Drug Resistance; Drug Screening Assays, Antitumor; Gamma Rays; Humans; Laryngeal Neoplasms; Methotrexate; Tumor Cells, Cultured; Vincristine | 1992 |
[Combined radiomodification in the treatment of patients with disseminated laryngeal cancer].
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Glucose; Humans; Hyperthermia, Induced; Laryngeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Staging; Radiation Injuries; Radiotherapy Dosage; Remission Induction | 1990 |
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Drug Evaluation; Fluorouracil; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Oropharyngeal Neoplasms | 1985 |
[Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Staging; Oropharyngeal Neoplasms; Prognosis; Vindesine | 1986 |
Multidrug chemotherapy using bleomycin, methotrexate, and cisplatin combined with radical radiotherapy in advanced head and neck cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Oropharyngeal Neoplasms | 1987 |
[Chemotherapy and partial surgery in epithelioma of the pharyngo-larynx].
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Combined Modality Therapy; Fluorouracil; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Pharyngeal Neoplasms | 1988 |
[Tumor and lymph node response to chemotherapy. Prognosis in cancer of the pyriform sinus and the lateral laryngeal margin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Methotrexate; Pharyngeal Neoplasms; Prognosis; Vincristine | 1988 |
Postcricoid carcinoma: a retrospective study of 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Vincristine | 1985 |
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Lip Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Gland Neoplasms; Thyroid Neoplasms; Tongue Neoplasms | 1971 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cystadenoma; Drug Synergism; Eye Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasms; Pharyngeal Neoplasms; Remission, Spontaneous; Skin Neoplasms | 1972 |
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Female; Fluorouracil; Humans; Intestinal Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Melanoma; Methotrexate; Mitomycins; Neoplasms; Palliative Care; Pharyngeal Neoplasms; Sarcoma; Thiotepa; Tongue Neoplasms; Urogenital Neoplasms; Vinblastine | 1971 |
Value of cytotoxic infusion in dyspnoea and dysphagia due to cancer.
Topics: Antineoplastic Agents; Cyclophosphamide; Deglutition Disorders; Dyspnea; Esophageal Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Methotrexate; Neoplasms; Pharyngeal Neoplasms | 1973 |
[Treatment of epidermoid carcinoma of the oro-pharyngo-laryngeal area with combination of methotrexate and bleomycin].
Topics: Aged; Bleomycin; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms; Thrombocytopenia | 1974 |
[Chemotherapy of cancers of the larynx and hypopharynx].
Topics: Adult; Aminocaproates; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Female; Glutathione; Humans; Injections, Intravenous; Laryngeal Neoplasms; Laryngectomy; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pharyngeal Neoplasms; Postoperative Care; Time Factors; Vinblastine | 1973 |
Treatment of carcinoma of the head and neck with intravenous methotrexate.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Palliative Care; Pharyngeal Neoplasms | 1968 |
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".
Topics: Adult; Aged; Anemia; Carcinoma, Squamous Cell; Cell Division; Drug Eruptions; Drug Synergism; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leucovorin; Leukopenia; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Mucous Membrane; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms | 1970 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Jaw Neoplasms; Laryngeal Neoplasms; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Salivary Glands; Thrombocytopenia; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
[Results of treatment of solid tumors with massive levels of methotrexate and folinic acid combination. Apropos of 49 cases].
Topics: Adult; Aged; Breast Neoplasms; Ear Neoplasms; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Laryngeal Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Nose Neoplasms; Remission, Spontaneous | 1973 |
Recurrent head and neck cancer: the results of treatment.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Lip Neoplasms; Lymphatic Metastasis; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Surgery, Plastic | 1974 |
Methotrexate in combination with radiotherapy in the treatment of squamous carcinomas of the head and neck.
Topics: Administration, Oral; Carcinoma, Squamous Cell; Cheek; Cobalt Radioisotopes; Female; Humans; Infusions, Parenteral; Laryngeal Neoplasms; Lip Neoplasms; Male; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Parotid Neoplasms; Radioisotope Teletherapy; Tongue Neoplasms; Tonsillar Neoplasms | 1974 |
Treatment of advanced carcinoma of the head and neck with a combination of high-dose infusions of methotrexate (NSC-740) and radiotherapy: a preliminary report on eleven cases.
Topics: Aged; Blood Platelets; Carcinoma, Squamous Cell; Female; Head; Head and Neck Neoplasms; Hematocrit; Hemoglobins; Humans; Laryngeal Neoplasms; Leucovorin; Leukocyte Count; Male; Methotrexate; Middle Aged | 1972 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Artery, Internal; Catheterization; Cyclophosphamide; Dactinomycin; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Laryngeal Neoplasms; Melanoma; Methods; Methotrexate; Mouth Neoplasms; Neoplasms; Osteosarcoma; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms; Skull Neoplasms; Vinblastine | 1972 |
Methotrexate in the treatment of squamous cell carcinomas of the head and neck.
Topics: Aged; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Leukopenia; Male; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Nausea; Neoplasms; Tongue Neoplasms; Vincristine | 1973 |
Chemoimmunotherapy for cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Evaluation Studies as Topic; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Isoniazid; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Male; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Parotid Neoplasms; Salivary Gland Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1973 |
Deaza aalogues of amethopterin (methotrexate).
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma; Cell Line; Columbidae; Enterococcus faecalis; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Leukemia L1210; Liver; Methotrexate; Protein Binding; Structure-Activity Relationship | 1971 |
Methotrexate plus Bacillus Calmette-Guérin (BCG) and isoniazid in the treatment of cancer of the head and neck.
Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Head; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Injections, Intravenous; Isoniazid; Laryngeal Neoplasms; Lip Neoplasms; Male; Methotrexate; Middle Aged; Mouth Floor; Mouth Neoplasms; Neoplasms; Tonsillar Neoplasms | 1972 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; Hodgkin Disease; Humans; Laryngeal Neoplasms; Liver Cirrhosis; Methotrexate; Morbidity; Myelitis; Pharyngeal Neoplasms; Radiotherapy; Radiotherapy Dosage; Spinal Cord; Uterine Cervical Neoplasms; Xerostomia | 1971 |
Radiation therapy and chemotherapy combination.
Topics: Administration, Oral; Antimetabolites; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Injections, Intra-Arterial; Injections, Intramuscular; Injections, Intravenous; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Pyrimidines | 1971 |
Treatment of squamous cell carcinoma of the head and neck with combined methotrexate and irradiation.
Topics: Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Pharyngeal Neoplasms; Retrospective Studies; Tongue Neoplasms | 1970 |
Management of cancer of the larynx.
Topics: Female; Glottis; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Male; Methotrexate | 1970 |
Treatment of advanced cancer of head and neck by large doses of methotrexate.
Topics: Administration, Oral; Head; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Methotrexate; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Paranasal Sinus Neoplasms; Pharyngeal Neoplasms; Skin Neoplasms | 1971 |
[Possibilities of systemic chemotherapy with methotrexate in the treatment of neglected forms of malignant neoplasms of the head and neck].
Topics: Head and Neck Neoplasms; Humans; Jaw Neoplasms; Laryngeal Neoplasms; Lip Neoplasms; Mandibular Neoplasms; Maxillary Neoplasms; Methotrexate; Mouth Neoplasms; Parotid Neoplasms; Sarcoma; Skin Neoplasms; Thyroid Neoplasms | 1971 |
Methotrexate therapy for squamous cell carcinomas of the head and neck. Intermittent intravenous dose program.
Topics: Adult; Aged; Blood Cell Count; Body Weight; Carcinoma, Squamous Cell; Ear Neoplasms; Epiglottis; Facial Neoplasms; Humans; Injections, Intravenous; Laryngeal Neoplasms; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Nasopharyngeal Neoplasms; Palatal Neoplasms; Pharyngeal Neoplasms; Tongue Neoplasms; Tonsillar Neoplasms | 1968 |
Combined treatment of tumours of the oto-rhino-laryngeal region by methotrexate and irradiation.
Topics: Esophageal Neoplasms; Humans; Laryngeal Neoplasms; Male; Maxillary Neoplasms; Methotrexate; Middle Aged; Mouth Neoplasms; Nasopharyngeal Neoplasms; Parotid Neoplasms; Tonsillar Neoplasms | 1966 |