Page last updated: 2024-08-25

methotrexate and Kidney Diseases

methotrexate has been researched along with Kidney Diseases in 190 studies

Research

Studies (190)

TimeframeStudies, this research(%)All Research%
pre-199054 (28.42)18.7374
1990's36 (18.95)18.2507
2000's30 (15.79)29.6817
2010's54 (28.42)24.3611
2020's16 (8.42)2.80

Authors

AuthorsStudies
Abdel-Moneim, AM; Alfwuaires, M; Alzahrani, AM; Elsawy, H; Khalil, M1
Akin, AT; Karabulut, D; Kaymak, E; Kuloglu, N; Ozturk, E; Yakan, B1
Aldossary, SA; Chohan, MS; Mohaini, MA; Tasleem Rasool, S1
Baumrin, E; Berna, R; Margolis, DJ; Mitra, N; Rosenbach, M1
Ab Hamid, S; Fu, Z; Jiang, Y; Shang, X; Wang, Z; Zhao, Q1
Çalışkan-Ak, E; Dursun, E; Gürel-Gökmen, B; Muhan, A; Özbeyli, D; Şener, G; Sivas, GG; Tufan, E; Tunali-Akbay, T; Yılmaz-Karaoğlu, S1
Al-Shaalan, NH; Sabry, D; Sherif, IO1
Cai, H; Cao, X; Chen, M; Duan, M; Feng, J; Li, J; Wang, W; Yang, C; Zhang, L; Zhang, W; Zhang, Y; Zhou, D; Zhu, T; Zhuang, J1
Abd-Elhalem, SS; Abu-El Magd, EE; El Zawawy, WK; El-Shinnawy, NA; Haggag, NZ1
Aldhahrani, A; Alkhedaide, A; Althobaiti, F; Mohamed, WA; Nassan, MA; Soliman, MM1
Asano, SH; Asano, Y; Hayashi, K; Matsumoto, Y; Morishita, M; Narazaki, M; Ohashi, K; Sada, KE; Wada, J; Watanabe, H; Yamamura, Y1
Ding, N; Gao, L; Gao, LH; Wang, XB; Wang, Z; Yang, YY; Zhang, LP1
Alarifi, S; Albasher, G; Alfarraj, S; Alkhatani, S; Almeer, R; Alqahtani, WS; Dar, AA; Fehaid, A; Moneim, AA1
Ashizawa, M; Ban, T; Fujiwara, SI; Hatano, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, S; Matsuoka, S; Minakata, D; Murahashi, R; Nagayama, T; Nakano, H; Nakashima, H; Oh, I; Ohmine, K; Sato, K; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R1
Akyol, Y; Erdemli-Kose, SB; Garli, S; Ozmen, O; Sahindokuyucu-Kocasari, F1
Alves, AM; Bettanin, BF; Gehringer, M; Goettert, MI; Laufer, S; Majolo, F; Rocha, CM1
Abo-Youssef, AM; Hassan, MIA; Hemeida, RAM; Osman, AT; Sharkawi, SMZ1
Benseler, SM; Cabral, DA; Charuvanij, S; Dancey, P; Eberhard, BA; Elder, ME; Foell, D; Hersh, AO; Huber, AM; Klein-Gitelman, M; Kostik, MM; Lawson, EF; Lee, T; Li, SC; Lubieniecka, JM; Luqmani, RA; Moorthy, LN; Morishita, KA; Nielsen, SM; Ristic, G; Shenoi, S; Toth, MB; Twilt, M; Yeung, RSM1
Ciğerci, İH; İlhan Çelik, Ö; Sakalli Çetin, E; Tetiker, H; Yılmaz, N1
Asci, H; Aydin, B; Bas, E; Ellidag, HY; Ozmen, O; Yilmaz, N1
Abid, S; Achour, A; Amara, I; Azzebi, A; Bacha, H; Bousabbeh, M; Guedri, Y; Rjiba-Touati, K; Salem, IB1
Aja, PM; Azubuike-Osu, SO; Ekeleme-Egedigwe, CA; Famurewa, AC; Maduagwuna, EK; Ufebe, OG1
Ilic, S; Jakovljevic, V; Kocic, G; Kocic, H; Stojanovic, M; Stojanovic, N; Stojiljkovic, N; Stojnev, S1
Fernández-Codina, A; Pope, JE; Walker, KM1
De Lavallaz, L; Musso, CG1
Sakai, N; Wada, T1
Severin, MJ; Torres, AM1
de Haan, J; Oude Munnink, T; Touw, D; van der Meer, A; van Kruchten, M1
Mamoudou, AD; Mikkelsen, TS; Schroeder, H; Tuckuviene, R; Wehner, PS1
Chuang, H; Fanale, M; Fayad, L; Fowler, N; Hagemeister, FB; Kwak, LW; McLaughlin, P; Neelapu, S; Oki, Y; Orlowski, RZ; Ouzounian, ST; Rodriguez, MA; Romaguera, JE; Samaniego, F; Vega, F; Wang, M; Westin, JR; Younes, A1
Aoki, H; Fujii, Y; Isogawa, M; Natsumeda, M; Ogura, R; Okada, M; Tsukamoto, Y; Yoshida, S1
Aiyer, R; Armaghani, A; Iqbal, S; Kazory, A1
Abdel-Raheem, IT; Khedr, NF1
Dalia, S; Forsyth, P; Jaglal, M; Price, S; Sokol, L1
Dabak, DO; Kocaman, N1
Armagan, HH; Armagan, I; Bayram, D; Candan, IA; Celik, E; Uğuz, AC; Yigit, A1
Aslaner, A; Aykaç, A; Bahar, L; Baştürk, A; Çakır, T; Durgut, H; Gül, M; Polat, C; Sabuncuoglu, MZ; Şehirli, AÖ1
El-Gowelli, HM; El-Gowilly, SM; Helmy, MM1
Badr, EA; Ragab, SM1
Ahmed, W; Nabil, T; Zaki, A1
Aksoy, N; Kocarslan, S; Oguz, E; Sezen, H; Tabur, S; Yilmaz, Z1
Ash, S; Cohen, IJ; Issakov, J; Kollender, Y; Shkalim-Zemer, V; Toledano, H; Yaniv, I1
Brown, V; Burton, B; Dabb, A; Holdhoff, M; Kinsman, K; Rouch, JA; Seung, AH1
Fayad, A; González, G; Robaina Sindín, J; Smuclir Quevedo, A; Vazquez, V1
Bozkus, F; Kurt, AH; Uremis, MM; Uremis, N1
Öztürk, İ; Sönmez, MF; Ulusoy, HB1
Djerada, Z; Feliu, C; Gozalo, C; Marquet, B; Millart, H; Oudart, JB1
Mu, Q; Wan, Y; Xiao, S; Xue, M1
Exton, LS; Kirby, B; Mohd Mustapa, MF; Smith, CH; Warren, RB; Weatherhead, SC; Yesudian, PD1
Cabello Zurita, C; Carretero Hernández, G; González Quesada, A; Grau Pérez, M; Hernández Fernández, CP; Valerón Almazán, P; Vilar Alejo, J1
Deray, G; Isnard-Bagnis, C; Janus, N; Karie, S; Launay-Vacher, V1
Celtikci, B; Deng, L; Friedman, HC; James, SJ; Krupenko, NI; Krupenko, SA; Lawrance, AK; Leclerc, D; Melnyk, S; Peterson, AC; Rozen, R1
Marrodán, L; Patiño-García, A; San-Julián, M; Sierrasesúmaga, L; Zalacaín, M1
Salgo, R; Thaçi, D1
Grier, HE; Janeway, KA1
Boulinguez, S1
Hakala, M; Immonen, K; Kautiainen, H; Vasala, M1
Olesińska, M; Wiesik-Szewczyk, E1
Adamson, PC; Balis, FM; Boron, M; Cole, DE; Eby, M; Fox, E; Ivy, P; Jayaprakash, N; Kim, A; Murphy, RF; O'Brien, M; Shalabi, A; Widemann, BC1
Abdulhadi, O; Qudsi, R; Sultan, I1
Bessell, EM; Dickinson, P; Dickinson, S; Salmon, J1
Cai, HB; Chen, ZP; Deng, Y; He, Y; Hu, CH; Lao, XX; Li, S; Li, TJ; Qin, JY; Wang, J; Wang, LL; Yang, J; Yang, YH1
Goto, N; Hayashi, K; Ohtsu, F; Sakakibara, J; Yano, R1
Battistella, M; Boulinguez, S1
Asl, NA; Asvadi, A; Asvadi, I; Hajipour, B; Khodadadi, A; Roshangar, L1
Çakır, T; Dulundu, E; Ercan, F; Özkan, E; Şehirli, AÖ; Şener, E; Şener, G; Topaloğlu, Ü1
Bachelez, H; Paul, C1
Kaykhaei, MA; Mashhadi, MA; Sanadgol, H1
Agard, C; Aslangul, E; Aumaître, O; Bienvenu, B; Boutemy, J; Broussolle, C; Comoz, F; Cordier, JF; Decaux, O; Dubois, A; Dufour, JF; Guillevin, L; Le Gallou, T; Mahr, A; Marie, I; Pagnoux, C; Pinède, L; Puéchal, X; Sève, P1
Bhagavath, B; Carson, SA; Clark, LE; Frishman, GN; Wheeler, CA1
Kher, A; Kher, V1
Belavic, JM1
Suzuki, Y1
Aldaz, A; Aquerreta, I; Giráldez, J; Sierrasesúmaga, L1
Arbus, GS; Bash, RO; Hansch, E; Leavey, PJ; Quigley, R; Saland, JM1
Bode, U; Diehl, V; Elter, T; Engert, A; Fleischhack, G; Heuer, T; Josting, A; Krause, AS; Weihrauch, MR1
Appenroth, D; Fleck, C; Hempel, L; Kentouche, K; Leder, C; Misselwitz, J; Rost, M; Zintl, F1
Balow, JE; Langford, CA1
Araghi, P; Bianchi, G; Ciabattoni, M; Icardi, A; Lazzarini, P; Romano, U1
MEYERS, MC; PENNER, JA; WEINTRAUB, LR1
BLENDIS, LM; SHRANK, AB1
Hurkacz, M; Orzechowska-Juzwenko, K; Swierkot, J; Szechiński, J; Wiela-Hojeńska, A; Wiland, P1
Cooper, JA; Eggert, M; Lock, BJ1
Crews, KR; Daw, NC; Link, MP; Liu, T; Meyer, WH; Panetta, JC; Rodriguez-Galindo, C; Tan, M1
Sugii, S1
Roberts, JT1
Budancamanak, M; Demirel, A; Kanter, M; Karakaya, C; Ocakci, A; Uysal, H1
Bulbuloglu, E; Cetinkaya, A; Kantarceken, B; Kurutas, EB1
Ayata, A; Oktem, F; Olgar, S; Ozguner, F; Uz, E; Uzare, E; Yilmaz, HR1
Inagaki, T; Takeyama, J; Umebayashi, H1
Harned, TM; Mascarenhas, L1
Atasever, T; Bakkaloglu, SA; Gursel, T; Kaya, Z; Kocak, U; Oktar, SO1
Auton, T; Borner, K; Fischer, L; Korfel, A; Martus, P; Müller, K; Schwartz, S; Thiel, E1
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T1
Bourgeois, P; Deray, G; Gandjbakhch, F; Janus, N; Karie, S; Launay-Vacher, V; Mai Ba, CU; Rozenberg, S1
Chamberlain, MC; Green, MR1
Poster, DS; Weiss, RB1
Powis, G1
Rubin, P1
Clarkson, AR; Healy, HG1
Blandy, JP; England, HR; Oliver, RT; Risdon, RA1
Alix, JL; Bayle, F; Cordonnier, D; Schaerer, R; Swiercz, P; Vialtel, P1
Bloomer, WD; Garnick, MB; Goldberg, ID1
Crowley, JJ; Deeg, HJ; Kennedy, MS; Siegel, M; Storb, R; Thomas, ED1
Atkinson, K; Biggs, JC; Concannon, AJ; Dodds, AJ; Hayes, J; Naidoo, D; Ralston, M1
Baum, E; Bleyer, WA; Fryer, C; Griffin, T; Lampkin, B; Lukens, J; Morgan, E; Movassaghi, N; Provisor, A; White, H1
Birch, R; Krauss, S; Oldham, R; Omura, GA; Robert, F1
Abelson, HT; Beardsley, GP; Fosburg, MT; Goorin, AM; Gorka, C; Link, D; Link, M1
Alberts, DS; Borst, J; Hilgers, RD; Miles, NJ; Skipper, BE; Standefer, JC1
Herrmann, R; Kreusser, W; Ritz, E; Tschöpe, W1
Canellos, GP; Ervin, TJ; Kirkwood, JM; Miller, D; Pitman, SW; Weichselbaum, R1
Gropp, C; Havemann, K1
Gordon-Smith, EC; Harris, R; Hows, J; Palmer, S1
Keusch, G1
Schilsky, RL1
Heidbreder, E; Heidland, A1
Gabizon, AA; Gorodetsky, R; Mou, X; Vexler, AM1
Hosaka, M; Kondoh, I; Kubota, Y; Miura, T; Noguchi, S; Shuin, T1
Dohy, H; Kakishita, E; Kanamaru, A; Kasai, M; Katoh, S; Kodera, Y; Moriyama, Y; Saitoh, H; Shibata, A; Takemoto, Y1
Fiter, J; Nolla, JM; Roig Escofet, D; Valverde, J1
Kitamura, Y; Komatsubara, S; Sakata, Y; Watanabe, M1
Balla, G; Békési, A; Kovács, I; Oláh, VA; Tóth, A1
Nakabayashi, K1
Catsoulakos, P; Karakiulakis, G; Pispirigos, K1
Dawes, P; Hassell, A1
Bruno, M; Cosseddu, D; Linari, F; Manganaro, M; Pellerito, R; Ravarino, N; Torchio, B; Urbano, D1
Brandis, M; Leititis, J; Mohrmann, M; von der Hardt, K; Zimmerhackl, RB1
Ekman, E; Müller-Suur, R; Seideman, P1
Kato, K; Kawai, M; Kitsuwa, S; Matsunaga, K; Okubo, T; Tani, K; Tsuzi, T1
Abdalla, MA; Bahakim, HM; el-Badawi, MG; Fadel, RA1
Andersson, B; Besien, K; Champlin, R; Cleary, K; Deisseroth, AB; Fischer, H; Fitzsimmons, W; Fritsche, H; Gajewski, J; Giralt, S; Ippoliti, C; Khouri, I; Le Bherz, D; Maher, R; Mehra, R; Przepiorka, D; Woo, M1
Arakawa, M; Hasegawa, H; Nakano, M; Nishi, S; Saito, T; Ueno, M1
Chalmers, IM; Gough, J; Janzen, L; Jeffery, JR1
Cachat, F; Guignard, JP1
Swierkot, J; Szechiński, J; Wiland, P1
Adamson, PC; Balis, FM; Montello, MJ; Murphy, RF; O'Brien, M; Sorensen, JM; Widemann, BC1
Connaghan, DG; Devine, SM; Dix, SP; Fitzsimmons, WE; Geller, RB; Heffner, LT; Hillyer, CD; Holland, HK; Keller, J; Lin, LB; Maher, RM; Maurer, D; O'Toole, K; Rodey, GE; Wingard, JR; Winton, EF1
Mihara, M; Moriya, Y; Takagi, N; Takeda, Y; Urakawa, K1
Nosaka, K; Suzuki, T1
Airoldi, M; Albanese, F; Di Costanzo, G; Fazio, M; Gariboldi, A; Mastromatteo, V; Pecchio, F1
Brunat-Mentigny, M; Cochat, P; Dubourg, L; Hadj-Aïssa, A; Koch Nogueira, PC; Schell, M1
Komatsuda, A; Miura, AB; Morita, K; Ohtani, H; Yamaguchi, A1
Bacci, G; Cesari, M; Fasano, MC; Ferrari, S; Lamanna, G; Zolezzi, C1
Chessells, JM; Hann, IM; Rees, H; Webb, DK1
Fiter Aresté, J; Gómez Vaquero, C; Nolla Solé, JM; Roig Escofet, D; Valverde García, J1
Kallenberg, CG; Stegeman, CA; Tervaert, JW1
Chan, GZ; Kapoor, M1
Lewis, V; Piatkowski, J; Rydholm, N; Sauer, M; Steiner, M1
Blum, R; Seymour, JF; Toner, G1
Jayne, DR1
Chan, H; Evans, WE; Pratt, CB1
Weismann, K1
Chabner, BA; Coleman, CN; Johns, DG; Myers, CE1
Hutters, L; Kristensen, LO; Weismann, K1
Katsume, A; Mihara, M; Takeda, Y1
Korstanje, MJ1
Alarcón-Segovia, D; Kraus, A1
Vogelzang, NJ1
Christian, MC; Grem, JL; King, SA; Sorensen, JM1
Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M1
Crom, WR; Gregory, RE; Pui, CH1
Ellman, MH; Ginsberg, D1
Arfeen, S; Carey, PJ; Jackson, G; Proctor, SJ; Stark, AN1
Bell, M; Bennett, K; Gent, M; Tugwell, P1
Deeg, HJ; McGuire, TR; Self, SG; St Pierre, BA; Sullivan, KM; Yee, GC; Zager, RA1
Kubar, J; Milano, G; Namer, M; Schneider, M; Thyss, A1
Dimery, IW; Legha, SS1
Bessell, EM; Bloom, HJ; Price, P; Thompson, H1
Abe, T; Inazawa, J; Misawa, S; Takeda, S; Takino, T; Taniwaki, M; Tsuda, S; Yashige, H; Yokota, S1
Cangir, A; Jaffe, N; Keifer, R; Robertson, R; Wang, A1
Crom, WR; Goren, MP; Horowitz, ME; Meyer, WH; Wright, RK1
Furue, H1
Appelbaum, FR; Banaji, M; Bensinger, WI; Buckner, CD; Clift, RA; Deeg, HJ; Flournoy, N; Kennedy, MS; Storb, R; Thomas, ED1
Appelbaum, FR; Beatty, P; Bensinger, W; Buckner, CD; Clift, R; Deeg, HJ; Doney, K; Irle, C; Kennedy, M; Storb, R1
Weinblatt, ME1
Hennigar, GR1
Clément, F1
Burry, HC1
Braun, HJ1
Schwartz, RS; Skinner, MD1
Mackay, IR1
Krieglstein, J1
Grob, PJ1
Fetterman, GH; Holliday, MA; Rubissow, MJ1
Bernard, J; Boiron, M; Bussel, A; Dreyfus, B; Jacquillat, C; Larrieu, MJ; Loisel, JP; Rouesse, T; Weil, M1
Anderson, LL; Collins, GJ; Oberfield, RA; Ojima, Y; Sullivan, RD1
Buck, AT; Taylor, DM; Threlfall, G1
Chanes, RE; Condit, PT; Joel, W1

Reviews

45 review(s) available for methotrexate and Kidney Diseases

ArticleYear
Methotrexate Cutaneous Ulceration: A Systematic Review of Cases.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:4

    Topics: Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Pancytopenia; Skin Neoplasms; Skin Ulcer

2022
How to rescue high-dose methotrexate induced nephrotoxicity and literature review about hemodiafiltration?
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:3

    Topics: Antidotes; Antimetabolites, Antineoplastic; Hemodiafiltration; Humans; Kidney Diseases; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Treatment Outcome; Young Adult

2020
Current jakinibs for the treatment of rheumatoid arthritis: a systematic review.
    Inflammopharmacology, 2021, Volume: 29, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinase Inhibitors; Kidney Diseases; Methotrexate; Piperidines; Purines; Pyrazoles; Pyrimidines; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome

2021
Chronobiology in nephrology: the influence of circadian rhythms on renal handling of drugs and renal disease treatment.
    International urology and nephrology, 2018, Volume: 50, Issue:12

    Topics: Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Blood Pressure; Cardiovascular Diseases; Chronopharmacokinetics; Circadian Rhythm; Diuretics; Furosemide; Humans; Kidney; Kidney Diseases; Methotrexate; Pharmaceutical Preparations; Water-Electrolyte Balance

2018
Treatment of moderate-to-severe plaque psoriasis.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2009, Volume: 144, Issue:6

    Topics: Abnormalities, Drug-Induced; Alefacept; Antibodies, Monoclonal; Clinical Trials as Topic; Contraindications; Cyclosporine; Etanercept; Female; Fumarates; Hematologic Diseases; Humans; Hypertension; Immunoglobulin G; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Photochemotherapy; Pregnancy; Pregnancy Complications; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retinoids; Severity of Illness Index; Tumor Necrosis Factor-alpha

2009
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects.
    The Lancet. Oncology, 2010, Volume: 11, Issue:7

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Hearing Loss; Heart Diseases; Humans; Ifosfamide; Infertility; Kidney Diseases; Methotrexate; Neoplasms, Second Primary; Neurotoxicity Syndromes; Osteosarcoma; Survivors

2010
[Prescription and surveillance of treatment by a systemic agent or biotherapy in psoriasis].
    Annales de dermatologie et de venereologie, 2010, Volume: 137, Issue:4 Suppl

    Topics: Biological Products; Contraindications; Cyclosporine; Drug Administration Routes; Drug Monitoring; Female; Folic Acid; Humans; Immunosuppressive Agents; Kidney Diseases; Latent Tuberculosis; Liver Cirrhosis; Medical History Taking; Methotrexate; Pregnancy; Pregnancy Complications; Psoriasis; Pulmonary Fibrosis; Recurrence; Tumor Necrosis Factor-alpha; Vaccination

2010
[Management of patients with systemic sclerosis].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010, Volume: 28, Issue:167

    Topics: Bone Marrow Transplantation; Cyclophosphamide; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Kidney Diseases; Lung Diseases, Interstitial; Methotrexate; Prognosis; Quality of Life; Raynaud Disease; Scleroderma, Systemic; Stem Cell Transplantation; Treatment Outcome

2010
Glucarpidase (Voraxaze) for methotrexate toxicity.
    The Medical letter on drugs and therapeutics, 2012, Mar-05, Volume: 54, Issue:1385

    Topics: Animals; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Metabolic Clearance Rate; Methotrexate

2012
Urogenital manifestations in Wegener granulomatosis: a study of 11 cases and review of the literature.
    Medicine, 2012, Volume: 91, Issue:2

    Topics: Adult; Aged; Constriction, Pathologic; Cystostomy; Follow-Up Studies; Genital Diseases, Male; Glucocorticoids; Granuloma, Plasma Cell; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Middle Aged; Nephrectomy; Prednisone; Prostatectomy; Recurrence; Retrospective Studies; Skin Ulcer; Stents; Transurethral Resection of Prostate; Ureteral Diseases; Young Adult

2012
Immunotherapy in renal diseases.
    The Medical clinics of North America, 2012, Volume: 96, Issue:3

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cyclophosphamide; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Methotrexate; Plasmapheresis; Prognosis; Recurrence; Rituximab

2012
New insights into the immunopathogenesis and treatment of small vessel vasculitis of the kidney.
    Current opinion in nephrology and hypertension, 2003, Volume: 12, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cyclophosphamide; Disease Models, Animal; Humans; Kidney; Kidney Diseases; Methotrexate; Mice; Mycophenolic Acid; Rituximab; Vasculitis

2003
[Kidney involvement in rheumatoid arthritis].
    Reumatismo, 2003, Volume: 55, Issue:2

    Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Autopsy; Biopsy; Cyclosporine; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Methotrexate; Nephritis, Interstitial; Penicillamine; Time Factors

2003
Infiltrative lung disease due to noncytotoxic agents.
    Clinics in chest medicine, 2004, Volume: 25, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Humans; Hydrochlorothiazide; Iatrogenic Disease; Kidney Diseases; Lung Diseases; Lung Diseases, Interstitial; Methotrexate; Narcotics; Organogold Compounds; Syndrome

2004
[Adverse effects of DMARDs in treatment of rheumatoid arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases, Interstitial; Male; Methotrexate; Reproduction; Sulfasalazine

2005
Chemotherapy for metastatic bladder cancer.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2005, Volume: 17, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cisplatin; Comorbidity; Doxorubicin; Humans; Kidney Diseases; Methotrexate; Neoplasm Metastasis; Phenotype; Prognosis; Randomized Controlled Trials as Topic; Survival; Urinary Bladder Neoplasms; Vinblastine

2005
[Adverse effects of conventional DMARDs and biologic DMARDs].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate

2007
The renal toxicity of cancer chemotherapeutic agents.
    Cancer treatment reviews, 1982, Volume: 9, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Cyclophosphamide; Dacarbazine; Humans; Kidney Diseases; Methotrexate; Mitomycins; Naphthacenes; Nitrosourea Compounds; Plicamycin; Streptozocin; Thioguanine

1982
Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs.
    Cancer treatment reviews, 1982, Volume: 9, Issue:2

    Topics: Antineoplastic Agents; Aspartic Acid; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Gallium; Humans; Kidney Diseases; Kinetics; Liver Diseases; Metabolic Clearance Rate; Methotrexate; Phosphonoacetic Acid; Protein Binding; Tegafur

1982
The Franz Buschke lecture: late effects of chemotherapy and radiation therapy: a new hypothesis.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Bleomycin; Bone Marrow Diseases; Brain Diseases; Cardiomyopathies; Carmustine; Cisplatin; Doxorubicin; Gastrointestinal Diseases; Humans; Kidney Diseases; Liver Diseases; Lung Diseases; Methotrexate; Neoplasms; Radiotherapy

1984
Urinary tract toxic effects of cancer therapy.
    The Journal of urology, 1984, Volume: 132, Issue:1

    Topics: Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Cystitis; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Methotrexate; Nephritis; Radiation Injuries; Radiation Tolerance; Radiotherapy; Semustine; Streptozocin; Ureteral Obstruction

1984
Nephrological complications of cancer therapy.
    Contributions to nephrology, 1982, Volume: 33

    Topics: Acute Kidney Injury; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Humans; Ifosfamide; Kidney; Kidney Diseases; Methotrexate; Mitomycin; Mitomycins; Nitrosourea Compounds; Vinblastine; Vincristine

1982
[Toxic lesions caused by cytostatic drugs].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Alopecia; Antineoplastic Agents; Arrhythmias, Cardiac; Blood Platelets; Blood Transfusion; Bone Marrow; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diarrhea; Digestive System; Doxorubicin; Female; Hair; Humans; Kidney Diseases; Lung; Male; Methotrexate; Methotrimeprazine; Mutation; Pericarditis; Pregnancy; Pulmonary Fibrosis; Thrombocytopenia; Vincristine

1980
[Kidney disorders caused by antineoplastic agents].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1994, Oct-10, Volume: 83, Issue:10

    Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Kidney Diseases; Methotrexate; Mitomycin; Nimustine

1994
Serious problems with methotrexate?
    British journal of rheumatology, 1994, Volume: 33, Issue:11

    Topics: Arthritis, Rheumatoid; Humans; Kidney Diseases; Liver Cirrhosis; Lung Diseases; Methotrexate

1994
[Renal damage in rheumatoid arthritis].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 1994, Volume: 46, Issue:1

    Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclosporine; Female; Glomerulonephritis; Gold; Humans; Kidney Diseases; Kidney Failure, Chronic; Male; Methotrexate; Middle Aged; Penicillamine; Vasculitis

1994
Cytostatics--induced tubular toxicity.
    The Clinical investigator, 1993, Volume: 71, Issue:10

    Topics: Antineoplastic Agents; Cisplatin; Humans; Ifosfamide; Kidney Diseases; Kidney Tubules; Methotrexate; Risk Factors

1993
[Pancytopenia and Pneumocystis carinii pneumonia associated with low dose methotrexate pulse therapy for rheumatoid arthritis--case report and review of literature].
    Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:3

    Topics: Age Factors; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Contraindications; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Pancytopenia; Pneumonia, Pneumocystis; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination

1996
[Drug-induced renal disorders in patients with rheumatoid arthritis].
    Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Humans; Kidney Diseases; Methotrexate; ortho-Aminobenzoates

1996
[The kidney in children under chemotherapy].
    Revue medicale de la Suisse romande, 1996, Volume: 116, Issue:12

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child; Cisplatin; Glomerular Filtration Rate; Humans; Ifosfamide; Kidney; Kidney Diseases; Kidney Function Tests; Methotrexate; Mitomycin; Semustine

1996
[Nephrotoxicity of antineoplastic drugs].
    Ryoikibetsu shokogun shirizu, 1997, Issue:16 Pt 1

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cisplatin; Cyclophosphamide; Humans; Ifosfamide; Kidney Diseases; Methotrexate; Streptozocin

1997
Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis.
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:2

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antilymphocyte Serum; Cyclophosphamide; Guanidines; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Isoxazoles; Kidney Diseases; Leflunomide; Methotrexate; Mycophenolic Acid; Prednisone; Remission Induction; Trimethoprim, Sulfamethoxazole Drug Combination; Tumor Necrosis Factor-alpha; Vasculitis

2001
Malignancy and renal disease.
    Critical care clinics, 2001, Volume: 17, Issue:3

    Topics: Acute Kidney Injury; Antineoplastic Agents; Bone Marrow Transplantation; Cisplatin; Cyclosporine; Hepatorenal Syndrome; Humans; Kidney Diseases; Methotrexate; Multiple Myeloma; Neoplasms; Renal Replacement Therapy

2001
Conventional treatment and outcome of Wegener's granulomatosis and microscopic polyangiitis.
    Cleveland Clinic journal of medicine, 2002, Volume: 69 Suppl 2

    Topics: Azathioprine; Cyclophosphamide; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Kidney Diseases; Methotrexate; Microcirculation; Secondary Prevention; Treatment Outcome; Vasculitis

2002
The clinical pharmacology of antineoplastic agents (first of two parts).
    The New England journal of medicine, 1975, May-22, Volume: 292, Issue:21

    Topics: Animals; Antineoplastic Agents; Asparaginase; Binding Sites; Biological Transport; Chemical and Drug Induced Liver Injury; Depression, Chemical; DNA, Neoplasm; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Kidney Diseases; Liver; Lung Diseases; Methotrexate; Mice; Neoplasms; Tetrahydrofolate Dehydrogenase

1975
Nephrotoxicity from chemotherapy: prevention and management.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:10

    Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Gallium; Humans; Ifosfamide; Kidney Diseases; Methotrexate; Mitomycin; Neoplasms; Nitrosourea Compounds; Plicamycin

1991
Clinical use of thymidine as a rescue agent from methotrexate toxicity.
    Investigational new drugs, 1991, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Kidney; Kidney Diseases; Male; Meta-Analysis as Topic; Methotrexate; Middle Aged; Thymidine

1991
Methotrexate in rheumatoid arthritis. Feedback on American College of Physicians guidelines.
    Annals of internal medicine, 1989, Apr-15, Volume: 110, Issue:8

    Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Humans; Kidney Diseases; Methotrexate; Societies, Medical; United States

1989
[Late effects of cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Antineoplastic Agents; Bone and Bones; Chemical and Drug Induced Liver Injury; Cisplatin; Female; Fibrosis; Glomerular Filtration Rate; Humans; Kidney Diseases; Liver Cirrhosis; Male; Methotrexate; Neoplasm Metastasis; Neoplasms; Pituitary Gland; Pregnancy; Testis

1987
Toxicity of low dose methotrexate in rheumatoid arthritis.
    The Journal of rheumatology. Supplement, 1985, Volume: 12 Suppl 12

    Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases

1985
[Clinical picture, diagnostics and therapy of amyloidoses].
    Medizinische Klinik, 1972, Oct-06, Volume: 67, Issue:40

    Topics: Adrenal Gland Diseases; Amyloidosis; Biopsy; Chloroquine; Chronic Disease; Gastrointestinal Diseases; Humans; Infections; Kidney Diseases; Liver Diseases; Methotrexate; Neoplasms; Pancreatic Diseases; Prognosis; Splenic Diseases

1972
Methotrexate in the treatment of psoriasis.
    The Medical letter on drugs and therapeutics, 1972, Jun-09, Volume: 14, Issue:12

    Topics: Abnormalities, Drug-Induced; Bone Marrow; Chemical and Drug Induced Liver Injury; Female; Hematologic Diseases; Humans; Kidney Diseases; Leucovorin; Liver; Methotrexate; Pregnancy; Psoriasis; Skin

1972
Immunosuppressive therapy of immunoinflammatory diseases.
    Rheumatology, 1974, Volume: 5, Issue:0

    Topics: Abnormalities, Multiple; Abortion, Spontaneous; Collagen Diseases; Cyclophosphamide; Female; Gastrointestinal Diseases; Hematologic Diseases; Immune System Diseases; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Leukopenia; Liver Function Tests; Lymphoma; Mercaptopurine; Methotrexate; Nervous System Diseases; Pregnancy

1974
[Plasma protein binding of drugs].
    Klinische Wochenschrift, 1969, Nov-01, Volume: 47, Issue:21

    Topics: Adult; Age Factors; Bilirubin; Blood Protein Disorders; Chemical Phenomena; Chemistry; Chromatography, Gel; Coumarins; Glucocorticoids; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Kidney; Kidney Diseases; Methotrexate; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Sulfaphenazole; Ultracentrifugation; Water

1969
[Current status of immunosuppressive therapy in non-neoplastic disorders].
    Schweizerische medizinische Wochenschrift, 1970, Apr-18, Volume: 100, Issue:16

    Topics: Arthritis; Autoimmune Diseases; Azathioprine; Bone Marrow; Bone Marrow Diseases; Chemical Phenomena; Chemistry; Cyclophosphamide; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infections; Kidney Diseases; Methotrexate; Prognosis; Skin Diseases

1970

Trials

24 trial(s) available for methotrexate and Kidney Diseases

ArticleYear
Extended duration of prehydration does not prevent nephrotoxicity or delayed drug elimination in high-dose methotrexate infusions: a prospectively randomized cross-over study.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Combined Modality Therapy; Cross-Over Studies; Female; Fluid Therapy; Follow-Up Studies; Humans; Infant; Infusions, Intravenous; Kidney Diseases; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Time Factors; Tissue Distribution; Young Adult

2014
Prospective phase II study of rituximab with alternating cycles of hyper-CVAD and high-dose methotrexate with cytarabine for young patients with high-risk diffuse large B-cell lymphoma.
    British journal of haematology, 2013, Volume: 163, Issue:5

    Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Hematologic Diseases; Humans; Kidney Diseases; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Risk; Rituximab; Thrombosis; Vincristine; Young Adult

2013
Pharmacodynamics of high-dose methotrexate in pediatric patients.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Algorithms; Antimetabolites, Antineoplastic; Area Under Curve; Child; Child, Preschool; Female; Fluorescence Polarization Immunoassay; Hematologic Diseases; Humans; Kidney Diseases; Linear Models; Logistic Models; Male; Methotrexate; Neoplasms; Predictive Value of Tests

2002
High-dose methotrexate pharmacokinetics and outcome of children and young adults with osteosarcoma.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Ifosfamide; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Treatment Outcome

2004
Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 2007, Volume: 24, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Kidney Diseases; Kidney Function Tests; Longitudinal Studies; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Turkey; Vincristine

2007
Glucarpidase (carboxypeptidase g2) intervention in adult and elderly cancer patients with renal dysfunction and delayed methotrexate elimination after high-dose methotrexate therapy.
    The oncologist, 2007, Volume: 12, Issue:11

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Kidney Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Renal Insufficiency; Risk Factors; Time Factors; Treatment Outcome

2007
Renal dysfunction during and after high-dose methotrexate.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Case-Control Studies; Central Nervous System Neoplasms; Creatinine; Dose-Response Relationship, Drug; Female; gamma-Glutamyl Hydrolase; Humans; Kidney; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2009
Acute renal toxicity with combined use of amphotericin B and cyclosporine after marrow transplantation.
    Transplantation, 1983, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Bone Marrow Transplantation; Child; Creatinine; Cyclosporins; Drug Therapy, Combination; Female; Humans; Kidney Diseases; Male; Methotrexate; Random Allocation

1983
Treatment of patients with metastatic osteogenic sarcoma: a report from the Children's Cancer Study Group.
    Cancer treatment reports, 1984, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Neoplasm Metastasis; Neutropenia; Osteosarcoma; Thrombocytopenia; Time Factors; Vincristine

1984
Randomized phase III comparison of three doxorubicin-based chemotherapy regimens in advanced non-small cell lung cancer: a Southeastern Cancer Study Group trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Humans; Kidney Diseases; Lung Neoplasms; Methotrexate; Middle Aged; Myeloproliferative Disorders; Nausea; Prognosis; Random Allocation; Time Factors

1984
Reduction of the systemic toxicity of cisplatin by intra-arterial hepatic route administration for liver malignancies.
    International journal of cancer, 1995, Mar-03, Volume: 60, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney Diseases; Leucovorin; Liver; Liver Neoplasms; Methotrexate; Neoplasms; Nervous System Diseases; Ovarian Neoplasms; Remission Induction; Spectrophotometry, Atomic; Tumor Cells, Cultured; Vinblastine

1995
FK506 treatment of graft-versus-host disease developing or exacerbating during prophylaxis and therapy with cyclosporin and/or other immunosuppressants. Japanese FK506 BMT Study Group.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Child; Chronic Disease; Cyclosporine; Female; Flushing; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Middle Aged; Nausea; Prednisolone; Tacrolimus; Treatment Outcome

1995
Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after matched unrelated donor marrow transplantation.
    Blood, 1996, Dec-01, Volume: 88, Issue:11

    Topics: Actuarial Analysis; Administration, Oral; Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow Transplantation; Creatinine; Disease-Free Survival; Drug Administration Schedule; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Diseases; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Salvage Therapy; Survival Analysis; Tacrolimus; Transplantation Conditioning

1996
The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host disease prophylaxis.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 1997, Volume: 3, Issue:1

    Topics: Adult; Bone Marrow Transplantation; Disease-Free Survival; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Histocompatibility; Humans; Hyperglycemia; Hypertension; Immunosuppressive Agents; Infections; Kidney Diseases; Life Tables; Liver Diseases; Male; Methotrexate; Middle Aged; Pilot Projects; Safety; Survival Analysis; Tacrolimus; Transplantation, Homologous; Treatment Outcome

1997
A novel antifolate, MX-68, inhibits the development of autoimmune disease in MRL/lpr mice.
    International archives of allergy and immunology, 1997, Volume: 113, Issue:4

    Topics: 2-Aminoadipic Acid; Administration, Oral; Animals; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Blood Urea Nitrogen; Cell Division; Cholesterol; DNA, Single-Stranded; Dose-Response Relationship, Drug; Female; Folic Acid Antagonists; Kidney Diseases; Lupus Nephritis; Lymph Nodes; Methotrexate; Mice; Mice, Inbred MRL lpr; Picrates; Proteinuria; Specific Pathogen-Free Organisms; Spleen

1997
Long-term nephrotoxicity of cisplatin, ifosfamide, and methotrexate in osteosarcoma.
    Pediatric nephrology (Berlin, Germany), 1998, Volume: 12, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Creatinine; Female; Humans; Ifosfamide; Kidney Diseases; Kidney Function Tests; Male; Methotrexate; Osteosarcoma

1998
Prospective evaluation of high-dose ifosfamide-related nephrotoxicity in young adult patients with recurrent osteosarcoma previously treated with cisplatin, methotrexate and standard-dose ifosfamide.
    Anti-cancer drugs, 1999, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Bone Neoplasms; Cisplatin; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Ifosfamide; Kidney; Kidney Diseases; Male; Methotrexate; Neoplasm Recurrence, Local; Osteosarcoma; Prospective Studies

1999
Recovery from toxicity associated with high-dose methotrexate: prognostic factors.
    Cancer treatment reports, 1977, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dehydration; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Infant; Kidney Diseases; Kidney Function Tests; Leucovorin; Liver Diseases; Liver Function Tests; Male; Methotrexate; Neoplasms; Pleural Effusion; Prognosis; Time Factors; Vomiting

1977
Minimal risk of chronic renal dysfunction in marrow transplant recipients treated with cyclosporine for 6 months.
    Bone marrow transplantation, 1989, Volume: 4, Issue:6

    Topics: Bone Marrow Transplantation; Creatinine; Cyclosporins; Drug Administration Schedule; Graft vs Host Disease; Humans; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methotrexate; Prospective Studies; Randomized Controlled Trials as Topic

1989
Sequential methotrexate, 5-fluorouracil, and cisplatin in the treatment of recurrent squamous-cell carcinoma of the head and neck: failure of hypertonic saline to reduce the nephrotoxicity of cisplatin.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Kidney Diseases; Male; Mannitol; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Random Allocation; Sodium Chloride

1986
Cyclosporine as prophylaxis for graft-versus-host disease: a randomized study in patients undergoing marrow transplantation for acute nonlymphoblastic leukemia.
    Blood, 1985, Volume: 65, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Bacterial Infections; Bone Marrow Transplantation; Cyclosporins; Depression; Graft vs Host Disease; Humans; Hypertension; Kidney Diseases; Length of Stay; Leukemia; Liver Diseases; Methotrexate; Middle Aged; Mycoses; Pulmonary Fibrosis; Random Allocation

1985
Marrow transplantation for leukemia following fractionated total body irradiation. A comparative trial of methotrexate and cyclosporine.
    Leukemia research, 1985, Volume: 9, Issue:10

    Topics: Adult; Bone Marrow Transplantation; Cyclosporins; Graft vs Host Disease; Humans; Kidney Diseases; Leukemia; Liver Diseases; Methotrexate; Middle Aged; Recurrence; Vascular Diseases; Whole-Body Irradiation

1985
Toxicity of low dose methotrexate in rheumatoid arthritis.
    The Journal of rheumatology. Supplement, 1985, Volume: 12 Suppl 12

    Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases

1985
Pharmacologic studies of methotrexate in cancer patients with uropathy.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 100, Issue:2

    Topics: Colonic Neoplasms; Humans; Injections, Intravenous; Kidney Diseases; Kidney Function Tests; Methotrexate; Neoplasms; Pelvic Neoplasms; Tritium

1970

Other Studies

122 other study(ies) available for methotrexate and Kidney Diseases

ArticleYear
Nephroprotective effect of naringin in methotrexate induced renal toxicity in male rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Caspase 3; Disease Models, Animal; Flavanones; Inflammation Mediators; Interleukin-6; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Rats; Tumor Necrosis Factor-alpha

2021
Evaluation by different mechanisms of the protective effects of vitamin B12 on methotrexate nephrotoxicity.
    Journal of molecular histology, 2022, Volume: 53, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Catalase; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin B 12; Vitamin B Complex

2022
Capsaicin ameliorate the nephrotoxicity induced by methotrexate.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Capsaicin; Disease Models, Animal; Inflammation Mediators; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Rats, Sprague-Dawley

2021
Evaluating the effect of methotrexate on the rate of renal fibrosis by elastography and fibrosis-related gene expression.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Feb-27, Volume: 67, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Elasticity Imaging Techniques; Fibrosis; Gene Expression; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Transforming Growth Factor beta

2022
Whey protein concentrate ameliorates the methotrexate-induced liver and kidney damage.
    The British journal of nutrition, 2023, 11-28, Volume: 130, Issue:10

    Topics: Animals; Antioxidants; Glutathione; Kidney; Kidney Diseases; Liver; Methotrexate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Whey Proteins

2023
    Biomolecules, 2019, 11-03, Volume: 9, Issue:11

    Topics: Animals; Ginkgo biloba; Humans; Kidney; Kidney Diseases; Male; Methotrexate; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding; Signal Transduction; TOR Serine-Threonine Kinases

2019
Intravenous methotrexate at a dose of 1 g/m
    American journal of hematology, 2020, Volume: 95, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cerebrospinal Fluid; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Kaplan-Meier Estimate; Kidney Diseases; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Mucositis; Neoplasm Invasiveness; Prednisone; Proportional Hazards Models; Prospective Studies; Recurrence; Rituximab; Vincristine

2020
Application of either nano fibrillated cellulose methotrexate or nano silicon dioxide methotrexate composites against renal fibrosis in leukemia rat model.
    International journal of biological macromolecules, 2020, Aug-15, Volume: 157

    Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers; Cellulose; Disease Models, Animal; Drug Carriers; Fibrosis; Kidney Diseases; Leukemia; Male; Methotrexate; Nanofibers; Nanoparticles; Rats; Silicon Dioxide

2020
The ameliorative impacts of Moringa oleifera leaf extract against oxidative stress and methotrexate-induced hepato-renal dysfunction.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation; Inflammation Mediators; Kidney; Kidney Diseases; Liver; Male; Methotrexate; Mice; Moringa oleifera; Oxidative Stress; Plant Extracts; Plant Leaves; Signal Transduction

2020
Risk of higher dose methotrexate for renal impairment in patients with rheumatoid arthritis.
    Scientific reports, 2020, 10-30, Volume: 10, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Japan; Kidney; Kidney Diseases; Male; Methotrexate; Middle Aged; Regression Analysis; Retrospective Studies; Surveys and Questionnaires

2020
The protective role of luteolin against the methotrexate-induced hepato-renal toxicity via its antioxidative, anti-inflammatory, and anti-apoptotic effects in rats.
    Human & experimental toxicology, 2021, Volume: 40, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antioxidant Response Elements; Apoptosis; Chemical and Drug Induced Liver Injury; Inflammation; Kidney; Kidney Diseases; Luteolin; Male; Methotrexate; Oxidative Stress; Protective Agents; Rats

2021
Risk factors for high-dose methotrexate-induced nephrotoxicity.
    International journal of hematology, 2021, Volume: 114, Issue:1

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Female; Hematologic Neoplasms; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Uric Acid; Young Adult

2021
Apigenin alleviates methotrexate-induced liver and kidney injury in mice.
    Human & experimental toxicology, 2021, Volume: 40, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Apigenin; Chemical and Drug Induced Liver Injury; Kidney Diseases; Male; Methotrexate; Mice; Molecular Structure; Oxidative Stress

2021
Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 155

    Topics: Acetylcysteine; Animals; Benzhydryl Compounds; Glucosides; Hesperidin; Inflammation; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Protective Agents; Rats; Signal Transduction

2021
Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Child; Cohort Studies; Cyclophosphamide; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Diseases; Lung Diseases; Male; Methotrexate; Mycophenolic Acid; Prospective Studies; Recurrence; Registries; Remission Induction; Retrospective Studies; Rituximab

2017
[Methotrexate-Induced Nephrotoxicity in Rats: Protective Effect of Mistletoe (Viscum album L.) Extract].
    Complementary medicine research, 2017, Volume: 24, Issue:6

    Topics: Animals; DNA Damage; Female; Kidney Diseases; Methotrexate; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Viscum album

2017
The impact of gallic acid on the methotrexate-induced kidney damage in rats.
    Journal of food and drug analysis, 2017, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Creatinine; Gallic Acid; Humans; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Uric Acid

2017
Recombinant human erythropoietin prevents etoposide- and methotrexate-induced toxicity in kidney and liver tissues via the regulation of oxidative damage and genotoxicity in Wistar rats.
    Human & experimental toxicology, 2018, Volume: 37, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Catalase; Chemical and Drug Induced Liver Injury; DNA Damage; Erythropoietin; Etoposide; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Liver; Male; Malondialdehyde; Methotrexate; Protective Agents; Rats, Wistar; Recombinant Proteins

2018
Antioxidant and anti-inflammatory effects of virgin coconut oil supplementation abrogate acute chemotherapy oxidative nephrotoxicity induced by anticancer drug methotrexate in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Coconut Oil; Dietary Supplements; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2017
The Encapsulation of Lycopene in Nanoliposomes Enhances Its Protective Potential in Methotrexate-Induced Kidney Injury Model.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Carotenoids; Kidney; Kidney Diseases; Lycopene; Male; Methotrexate; Rats; Rats, Wistar

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Calcium Channels; Cyclophosphamide; Endothelin Receptor Antagonists; Glucocorticoids; Humans; Hydroxychloroquine; Hypertension, Pulmonary; Immunosuppressive Agents; Kidney Diseases; Lung Diseases, Interstitial; Methotrexate; Mycophenolic Acid; Phosphodiesterase 5 Inhibitors; Prostaglandins; Raynaud Disease; Rituximab; Scleroderma, Systemic

2018
[Immunosuppressants-induced kidney injury].
    Nihon Jinzo Gakkai shi, 2016, Volume: 58, Issue:7

    Topics: Humans; Immunosuppressive Agents; Kidney Diseases; Methotrexate; Ribonucleosides; TOR Serine-Threonine Kinases

2016
Time course effects of methotrexate on renal handling of water and electrolytes in rats. Role of aquaporin-2 and Na-K-2Cl-cotransporter.
    Toxicology letters, 2019, Sep-01, Volume: 311

    Topics: Animals; Aquaporin 2; Biomarkers; Chlorides; Electrolytes; Kidney Diseases; Kidney Tubules; Male; Methotrexate; Potassium; Rats, Wistar; Renal Reabsorption; Sodium; Solute Carrier Family 12, Member 1; Time Factors; Urodynamics; Water

2019
Reversible Impaired Methotrexate Clearance After Platinum-Based Chemotherapy for Osteosarcoma.
    Therapeutic drug monitoring, 2019, Volume: 41, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Interactions; Female; Humans; Kidney Diseases; Leucovorin; Methotrexate; Morphine; Mucositis; Osteosarcoma

2019
Advantages of dose-dense methotrexate protocol for primary central nervous system lymphoma: comparison of two different protocols at a single institution.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Academies and Institutes; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Hematologic Diseases; Hospitals, University; Humans; Kaplan-Meier Estimate; Kidney Diseases; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Procarbazine; Remission Induction; Retrospective Studies; Treatment Outcome; Vincristine; Young Adult

2013
Methotrexate nephrotoxicity: Novel treatment, new approach.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:4

    Topics: Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged

2013
Renoprotective effects of montelukast, a cysteinyl leukotriene receptor antagonist, against methotrexate-induced kidney damage in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:4

    Topics: Acetates; Animals; Antimetabolites, Antineoplastic; Cyclopropanes; Glutathione; Kidney; Kidney Diseases; Leukotriene Antagonists; Male; Malondialdehyde; Methotrexate; NF-kappa B; Peroxidase; Protective Agents; Quinolines; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2014
What is the optimal dose of high-dose methotrexate in the initial treatment of primary central nervous system lymphoma?
    Leukemia & lymphoma, 2015, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Treatment Outcome; Young Adult

2015
Effects of silymarin on methotrexate-induced nephrotoxicity in rats.
    Renal failure, 2015, Volume: 37, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Disease Models, Animal; Kidney Diseases; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Silymarin

2015
Effects of pentoxifylline and alpha lipoic acid on methotrexate-induced damage in liver and kidney of rats.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:3

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Kidney Diseases; Male; Methotrexate; Pentoxifylline; Rats; Rats, Sprague-Dawley; Thioctic Acid

2015
The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Interleukin-1beta; Kidney; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Thioctic Acid; Tumor Necrosis Factor-alpha

2015
Pioglitazone ameliorates methotrexate-induced renal endothelial dysfunction via amending detrimental changes in some antioxidant parameters, systemic cytokines and Fas production.
    Vascular pharmacology, 2015, Volume: 74

    Topics: Animals; Antioxidants; Cytokines; fas Receptor; Glutathione; Kidney; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Pioglitazone; Rats; Rats, Wistar; Thiazolidinediones

2015
Evaluation of serum and urine fetuin-A levels in children with acute lymphoblastic leukemia during and after high-dose methotrexate therapy: Relation to toxicity.
    Hematology (Amsterdam, Netherlands), 2016, Volume: 21, Issue:2

    Topics: Adolescent; alpha-2-HS-Glycoprotein; Child; Child, Preschool; Female; Humans; Infant; Kidney Diseases; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2016
Prevention of methotrexate-induced nephrotoxicity by concomitant administration of garlic aqueous extract in rat.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:3

    Topics: Adenosine Deaminase; Animals; Calcium; Catalase; Creatinine; Disease Models, Animal; Garlic; Glutathione; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Nitric Oxide; Phosphorus; Plant Extracts; Potassium; Rats; Rats, Wistar; Sodium; Urea

2015
Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Carotenoids; Drug Therapy, Combination; Glutathione; Interleukin-1beta; Kidney Diseases; Lycopene; Male; Melatonin; Methotrexate; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2015
Highly effective reduced toxicity dose-intensive pilot protocol for non-metastatic limb osteogenic sarcoma (SCOS 89).
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Substitution; Etoposide; Female; Follow-Up Studies; Hearing Loss; Humans; Ifosfamide; Kidney Diseases; Leucovorin; Male; Methotrexate; Osteosarcoma; Pilot Projects; Stroke Volume; Survival Rate; Treatment Outcome; Young Adult

2015
Comparison of enteral and parenteral methods of urine alkalinization in patients receiving high-dose methotrexate.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2017, Volume: 23, Issue:1

    Topics: Antacids; Citrates; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Male; Methotrexate; Middle Aged; Retrospective Studies; Sodium Acetate; Sodium Bicarbonate; Sodium Citrate; Urine

2017
[Clinical practice guideline for ANCA-associated vasculitis with renal involvement].
    Medicina, 2015, Volume: 75 Suppl 1

    Topics: Adult; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Azathioprine; Child; Clinical Trials as Topic; Cyclophosphamide; Evidence-Based Medicine; Glucocorticoids; Humans; Induction Chemotherapy; Kidney Diseases; Maintenance Chemotherapy; Methotrexate; Organ Dysfunction Scores; Plasmapheresis; Recurrence; Severity of Illness Index

2015
The protective role of G protein-coupled estrogen receptor 1 (GPER-1) on methotrexate-induced nephrotoxicity in human renal epithelium cells.
    Renal failure, 2016, Volume: 38, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cells, Cultured; Epithelial Cells; Estradiol; Humans; Kidney Diseases; Kidney Tubules, Proximal; Methotrexate; Nitriles; Phenols; Propionates; Protective Agents; Pyrazoles; Receptors, Estrogen

2016
Protective effect of propolis on methotrexate-induced kidney injury in the rat.
    Renal failure, 2016, Volume: 38, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Cytoprotection; Heat-Shock Proteins; Kidney Diseases; Methotrexate; Oxidative Stress; Propolis; Rats; Rats, Wistar; Treatment Outcome

2016
Analytical interference in the therapeutic drug monitoring of methotrexate.
    Annales de biologie clinique, 2016, Jun-01, Volume: 74, Issue:3

    Topics: Adolescent; Bone Neoplasms; Contraindications; Cross Reactions; Drug Monitoring; Drug Substitution; Fluorescence Polarization Immunoassay; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma

2016
Spontaneous renal hemorrhage caused by invasive mole: a case report.
    European journal of gynaecological oncology, 2016, Volume: 37, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Etoposide; Female; Hemorrhage; Humans; Hydatidiform Mole, Invasive; Kidney Diseases; Leucovorin; Methotrexate; Pregnancy; Uterine Neoplasms; Vincristine

2016
British Association of Dermatologists' guidelines for the safe and effective prescribing of methotrexate for skin disease 2016.
    The British journal of dermatology, 2016, Volume: 175, Issue:1

    Topics: Adult; Alcohol Drinking; Biological Products; Bone Marrow Diseases; Checklist; Chemical and Drug Induced Liver Injury; Chickenpox; Child; Counseling; Cyclosporine; Dermatologic Agents; Drug Administration Routes; Drug Administration Schedule; Drug Approval; Drug Interactions; Drug Monitoring; Drug Overdose; Evidence-Based Medicine; Female; Hepatitis, Viral, Human; HIV Infections; Humans; Intraoperative Complications; Kidney Diseases; Lung Diseases; Methotrexate; Nausea; Neoplasms; Off-Label Use; Patient Education as Topic; Patient Safety; Pregnancy; Pregnancy Complications; Retinoids; Skin Diseases; Tuberculosis; Ultraviolet Rays; Vaccination

2016
Effectiveness and safety of Methotrexate in psoriasis: an eight-year experience with 218 patients.
    The Journal of dermatological treatment, 2017, Volume: 28, Issue:5

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Female; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Treatment Outcome

2017
[Chemotherapy and renal toxicity].
    Bulletin du cancer, 2008, May-28, Volume: 95 FMC Onco

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carboplatin; Carmustine; Cisplatin; Deoxycytidine; Gemcitabine; Humans; Kidney; Kidney Diseases; Lomustine; Methotrexate; Organoplatinum Compounds; Oxaliplatin

2008
Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice.
    Pharmacogenetics and genomics, 2008, Volume: 18, Issue:7

    Topics: Animals; Cells, Cultured; Female; Gene Expression; Homocysteine; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Polymorphism, Single Nucleotide

2008
Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression.
    The Journal of pediatrics, 2009, Volume: 154, Issue:5

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Case-Control Studies; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gastrointestinal Diseases; Genotype; Hematologic Diseases; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolate Dehydrogenase

2009
More evidence of declining incidence of amyloidosis associated with inflammatory rheumatic diseases.
    Scandinavian journal of rheumatology, 2010, Volume: 39, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; Antirheumatic Agents; Blood Sedimentation; Creatinine; Female; Finland; Humans; Incidence; Kidney; Kidney Diseases; Kidney Transplantation; Male; Methotrexate; Middle Aged; Prevalence; Proteinuria; Rectum; Rheumatic Diseases; Subcutaneous Fat, Abdominal; Young Adult

2010
Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Sep-01, Volume: 28, Issue:25

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; gamma-Glutamyl Hydrolase; Humans; Infant; Kidney Diseases; Leucovorin; Male; Methotrexate; Middle Aged; Thymidine

2010
Low-dose carboxypeptidase-G2 for methotrexate toxicity in a child.
    Pediatric blood & cancer, 2010, Dec-15, Volume: 55, Issue:7

    Topics: Adolescent; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma

2010
Increasing age at diagnosis and worsening renal function in patients with primary central nervous system lymphoma.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Aged; Aging; Central Nervous System Neoplasms; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Longitudinal Studies; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Statistics, Nonparametric

2011
[The dissemination of CMV in urine of different group from Guangxi and the relationship between CMV infection and renal disease].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2010, Volume: 24, Issue:3

    Topics: China; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Ethnicity; Female; Humans; Infant, Newborn; Kidney Diseases; Kidney Transplantation; Methotrexate; Polymerase Chain Reaction; Pregnancy

2010
[Risk factors and subjective symptoms of drug-induced leucopenia].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:1

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Autoimmune Diseases; Case-Control Studies; Child; Databases, Factual; Female; Humans; Kidney Diseases; Leukopenia; Logistic Models; Male; Methimazole; Methotrexate; Middle Aged; Risk Factors; Ritodrine; Sex Factors; Ticlopidine; Young Adult

2011
[Update on psoriasis at the Dermatology Day conference, Paris 2010].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:2 Suppl 2

    Topics: Comorbidity; Creatinine; Cyclosporine; Dermatologic Agents; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Severity of Illness Index

2011
Protective effect of pentoxyfilline in renal toxicity after methotrexate administration.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blood Urea Nitrogen; Creatinine; Cytoprotection; Disease Models, Animal; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Pentoxifylline; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha

2011
Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Interleukin-1beta; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha

2011
[Choice of therapy based on clinical setting].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:12

    Topics: Age Factors; Comorbidity; Contraindications; Cyclosporine; Decision Making; Dermatologic Agents; Female; Hepatic Insufficiency; Humans; Kidney Diseases; Latent Tuberculosis; Mental Disorders; Methotrexate; Pregnancy; Psoriasis; Risk Factors; Skin Neoplasms

2011
Low prevalence of high-dose methotrexate nephropathy in patients with malignancy.
    Iranian journal of kidney diseases, 2012, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Prospective Studies; Young Adult

2012
Role of routine monitoring of liver and renal function during treatment of ectopic pregnancies with single-dose methotrexate protocol.
    Fertility and sterility, 2012, Volume: 98, Issue:1

    Topics: Abortifacient Agents, Nonsteroidal; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Diagnostic Tests, Routine; Dose-Response Relationship, Drug; Female; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Liver Function Tests; Methotrexate; Middle Aged; Monitoring, Physiologic; Predictive Value of Tests; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Young Adult

2012
Voraxaze treats toxic methotrexate levels.
    The Nurse practitioner, 2012, Sep-10, Volume: 37, Issue:9

    Topics: Drug Approval; Drug Interactions; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Methotrexate; Nurse Practitioners; Practice Guidelines as Topic

2012
[Anti-rheumatic drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

    Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate

2012
Effective removal of methotrexate by high-flux hemodialysis.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:10

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Female; Fluorescence Polarization Immunoassay; gamma-Glutamyl Hydrolase; Half-Life; Humans; Hypokalemia; Hypophosphatemia; Infusions, Intravenous; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Renal Dialysis; Rhabdomyosarcoma

2002
Carboxypeptidase-G2 rescue in cancer patients with delayed methotrexate elimination after high-dose methotrexate therapy.
    Leukemia & lymphoma, 2002, Volume: 43, Issue:11

    Topics: Adult; Antidotes; Female; gamma-Glutamyl Hydrolase; Humans; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasms; Osteosarcoma; Treatment Outcome

2002
Influence of high-dose methotrexate therapy (HD-MTX) on glomerular and tubular kidney function.
    Medical and pediatric oncology, 2003, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Diseases; Kidney Tubules; Male; Methotrexate; Prospective Studies; Proteinuria

2003
ACUTE URIC ACID NEPHROPATHY IN LEUKEMIA. REPORT OF A CASE TREATED WITH PERITONEAL DIALYSIS.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Acute Kidney Injury; Adolescent; Blood; Dialysis; Humans; Kidney Diseases; Leukemia; Mercaptopurine; Metabolism; Methotrexate; Peritoneal Dialysis; Renal Dialysis; Renal Insufficiency; Toxicology; Uric Acid; Urine

1964
FOLIC-ACID ANTAGONISTS IN TREATMENT OF PSORIASIS.
    British medical journal, 1965, Jul-17, Volume: 2, Issue:5454

    Topics: Drug Therapy; Duodenal Ulcer; Folic Acid Antagonists; Kidney Diseases; Kidney Tubules; Leukopenia; Melena; Methotrexate; Mouth Diseases; Necrosis; Pathology; Psoriasis; Toxicology

1965
[Renal tubular dysfunction in patients with rheumatoid arthritis starting with low dose of methotrexate].
    Polskie Archiwum Medycyny Wewnetrznej, 2003, Volume: 110, Issue:2

    Topics: Acetylglucosaminidase; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; Kidney Tubules; Male; Methotrexate; Middle Aged

2003
Protective effects of thymoquinone and methotrexate on the renal injury in collagen-induced arthritis.
    Archives of toxicology, 2006, Volume: 80, Issue:11

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzoquinones; Kidney Diseases; Male; Methotrexate; Protective Agents; Rats; Rats, Wistar

2006
The effects of N-acetylcysteine on methotrexate-induced oxidative renal damage in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Glutathione; Humans; Kidney; Kidney Diseases; Methotrexate; Oxidants; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar

2007
Methotrexate-induced renal oxidative stress in rats: the role of a novel antioxidant caffeic acid phenethyl ester.
    Toxicology and industrial health, 2006, Volume: 22, Issue:6

    Topics: Animals; Caffeic Acids; Catalase; Free Radical Scavengers; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Methotrexate; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2006
Renal involvement in a patient with juvenile idiopathic arthritis presenting after treatment for Hodgkin lymphoma.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:5

    Topics: Arthritis, Juvenile; Child; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Hematuria; Hodgkin Disease; Humans; Kidney Diseases; Methotrexate; Methylprednisolone; Prednisolone; Proteinuria; Sulfasalazine; Treatment Outcome

2007
Severe methotrexate toxicity precipitated by intravenous radiographic contrast.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:7

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow; Child; Contrast Media; Female; Humans; Kidney Diseases; Male; Methotrexate; Mucositis; Tomography, X-Ray Computed

2007
Kidney disease in RA patients: prevalence and implication on RA-related drugs management: the MATRIX study.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:3

    Topics: Adult; Age Distribution; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Comorbidity; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Function Tests; Male; Methotrexate; Middle Aged; Prevalence; Prospective Studies; Proteinuria; Risk Assessment; Sex Distribution; Urinalysis

2008
Renal complications of cytotoxic therapy.
    Australian and New Zealand journal of medicine, 1983, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents; Asparaginase; Cisplatin; Cyclophosphamide; Cytarabine; Dogs; Fluorouracil; Humans; Kidney Diseases; Methotrexate; Mitomycins; Neoplasms; Nitrosourea Compounds; Plicamycin; Procarbazine; Streptozocin; Syndrome

1983
Methotrexate in the treatment of metastatic and recurrent primary transitional cell carcinoma.
    The Journal of urology, 1984, Volume: 131, Issue:3

    Topics: Aged; Carcinoma, Transitional Cell; Drug Eruptions; Humans; Kidney Diseases; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms

1984
[Nephrotoxicity of antitumor chemotherapy].
    Presse medicale (Paris, France : 1983), 1984, Apr-28, Volume: 13, Issue:18

    Topics: Antineoplastic Agents; Cisplatin; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Humans; Kidney Diseases; Methotrexate; Mitomycin; Mitomycins; Nitrosourea Compounds; Plicamycin

1984
Cyclosporin A associated nephrotoxicity in the first 100 days after allogeneic bone marrow transplantation: three distinct syndromes.
    British journal of haematology, 1983, Volume: 54, Issue:1

    Topics: Acute Kidney Injury; Anemia, Aplastic; Bilirubin; Bone Marrow Transplantation; Creatinine; Cyclosporins; Humans; Kidney Diseases; Leukemia; Methotrexate; Purpura, Thrombotic Thrombocytopenic; Syndrome; Time Factors; Uremia

1983
Methotrexate-induced renal impairment: clinical studies and rescue from systemic toxicity with high-dose leucovorin and thymidine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Child; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Inulin; Kidney Diseases; Kinetics; Leucovorin; Methotrexate; Neoplasms; Thymidine

1983
Phase II and pharmacokinetic study of high-dose methotrexate in the treatment of advanced gynecologic malignancy. A Southwest Oncology Group Trial.
    Gynecologic oncology, 1984, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Genital Neoplasms, Female; Hematologic Diseases; Humans; Kidney Diseases; Kinetics; Leucovorin; Methotrexate; Middle Aged; Nausea; Time Factors

1984
Increased therapeutic index using moderate dose methotrexate and leucovorin twice weekly vs. weekly high dose methotrexate-leucovorin in patients with advanced squamous carcinoma of the head and neck: a safe new effective regimen.
    Cancer, 1981, May-15, Volume: 47, Issue:10

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Gastrointestinal Diseases; Head and Neck Neoplasms; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prognosis

1981
Immunosuppression with cyclosporin A in allogeneic bone marrow transplantation for severe aplastic anaemia: preliminary studies.
    British journal of haematology, 1981, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporins; Female; Graft Survival; Graft vs Host Reaction; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Middle Aged; Peptides, Cyclic; Transplantation, Homologous

1981
[Drug-induced kidney disorders].
    Schweizerische medizinische Wochenschrift, 1982, Mar-13, Volume: 112, Issue:11

    Topics: Aminoglycosides; Anti-Bacterial Agents; Glomerulonephritis; Humans; Ischemia; Kidney; Kidney Diseases; Methotrexate; Nephritis, Interstitial

1982
Renal and metabolic toxicities of cancer chemotherapy.
    Seminars in oncology, 1982, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Cisplatin; Drug Administration Schedule; Electrolytes; Glomerular Filtration Rate; Humans; Kidney Diseases; Methotrexate; Neoplasms; Nitrosourea Compounds; Nucleic Acids; Uric Acid

1982
[Toxic nephropathies (author's transl)].
    Klinische Wochenschrift, 1980, Feb-01, Volume: 58, Issue:3

    Topics: Analgesics; Drug Hypersensitivity; Ethylene Glycols; Glomerulonephritis; Humans; Hypercalcemia; Kidney Concentrating Ability; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubular Necrosis, Acute; Methicillin; Methotrexate; Nephritis, Interstitial; Oxalates

1980
Schedule-intensified M-VAC chemotherapy for advanced urothelial cancer with recombinant human granulocyte colony stimulating factor (rhG-CSF).
    International journal of urology : official journal of the Japanese Urological Association, 1994, Volume: 1, Issue:2

    Topics: Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Retrospective Studies; Urologic Neoplasms; Vinblastine

1994
[Methotrexate treatment of amyloidosis secondary to rheumatoid arthritis].
    Revista clinica espanola, 1995, Volume: 195, Issue:6

    Topics: Amyloidosis; Arthritis, Rheumatoid; Female; Humans; Kidney Diseases; Kidney Function Tests; Male; Methotrexate; Middle Aged; Retrospective Studies; Time Factors

1995
[Comparative study on urinary parameters reflecting renal damage during chemotherapy for urological cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:2

    Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Aminopeptidases; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; CD13 Antigens; Cisplatin; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Etoposide; Humans; Ifosfamide; Kidney Diseases; Male; Methotrexate; Middle Aged; Prostatic Neoplasms; Proteinuria; Urinary Bladder Neoplasms; Vincristine

1993
Urinary N-acetyl-beta-D-glucosaminidase activity in leukaemic children during high-dose methotrexate therapy.
    Haematologia, 1995, Volume: 26, Issue:3

    Topics: Acetylglucosaminidase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Burkitt Lymphoma; Child; Creatinine; Diuresis; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Kidney Tubules, Proximal; Leucovorin; Leukemia; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1995
Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Azasteroids; Blood Glucose; Chemical and Drug Induced Liver Injury; Chlorambucil; Cholesterol; Cisplatin; Epirubicin; gamma-Glutamyltransferase; Kidney; Kidney Diseases; Liver Diseases; Male; Methotrexate; Nitrogen; Nitrogen Mustard Compounds; Potassium; Rats; Rats, Wistar; Sodium; Weight Loss

1993
Renal effects of low dose methotrexate in rheumatoid arthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:7

    Topics: Adult; Aged; Arthritis, Rheumatoid; Chromium Radioisotopes; Dose-Response Relationship, Drug; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Technetium Tc 99m Mertiatide

1993
Nephrotoxicity of low-dose methotrexate in guinea pigs: an ultrastructural study.
    Nephron, 1996, Volume: 73, Issue:3

    Topics: Animals; Antidotes; Antimetabolites, Antineoplastic; Blood Cell Count; Bone Marrow; Guinea Pigs; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Leucovorin; Methotrexate; Microscopy, Electron

1996
Response to methotrexate in a patient with idiopathic eosinophilic fasciitis, morphea, IgM hypergammaglobulinemia, and renal involvement.
    The Journal of rheumatology, 1995, Volume: 22, Issue:10

    Topics: Adult; Eosinophilia; Fasciitis; Humans; Hypergammaglobulinemia; Immunoglobulin M; Kidney Diseases; Male; Methotrexate; Scleroderma, Localized

1995
N-acetyl-beta-D-glucosaminidase urinary excretion as an early indicator of kidney dysfunction in rheumatoid arthritis patients on low-dose methotrexate treatment.
    British journal of rheumatology, 1997, Volume: 36, Issue:1

    Topics: Acetylglucosaminidase; Adult; Aged; Albuminuria; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Female; Humans; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Uric Acid

1997
Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Antidotes; Antimetabolites, Antineoplastic; Carboxypeptidases; Child; Child, Preschool; Female; Humans; Infant; Kidney; Kidney Diseases; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Thymidine

1997
[Urinary lysozyme, beta-2-microglobulin, and alpha-glucosidase during cisplatin therapy].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Mar-30, Volume: 59, Issue:3

    Topics: alpha-Glucosidases; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Betamethasone; Biomarkers; Bleomycin; Cisplatin; Diuresis; Fluid Therapy; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Methotrexate; Mouth Neoplasms; Muramidase; Neoplasm Proteins; Predictive Value of Tests; Sensitivity and Specificity; Vincristine

1983
Remission of the nephrotic syndrome in a patient with renal amyloidosis due to rheumatoid arthritis treated with prednisolone and methotrexate.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:5

    Topics: Amyloidosis; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Kidney Diseases; Methotrexate; Middle Aged; Nephrotic Syndrome; Prednisolone; Remission Induction

1998
Are glomerular filtration rate estimations necessary before high dose methotrexate?
    Archives of disease in childhood, 1999, Volume: 81, Issue:4

    Topics: Antimetabolites, Antineoplastic; Child; Cost-Benefit Analysis; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Humans; Kidney Diseases; Male; Methotrexate

1999
[Secondary amyloidosis in rheumatoid arthritis. A clinical study of 29 patients].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:12

    Topics: Adult; Aged; Amyloidosis; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Prognosis

1999
Nephrotoxicity due to intermediate-dose methotrexate without rescue in an obese adolescent with acute lymphoblastic leukemia.
    Pediatric hematology and oncology, 2002, Volume: 19, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Humans; Kidney Diseases; Leucovorin; Male; Methotrexate; Obesity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radioisotope Renography

2002
Significant impairment of high-dose methotrexate clearance following vancomycin administration in the absence of overt renal impairment.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bone Neoplasms; Drug Interactions; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Methotrexate; Osteosarcoma; Vancomycin

2002
Methotrexate therapy for psoriasis in elderly patients with impaired renal function.
    Acta dermato-venereologica, 1977, Volume: 57, Issue:2

    Topics: Age Factors; Aged; Humans; Kidney Diseases; Methotrexate; Psoriasis

1977
Renal function and the rate of disappearance of methotrexate from serum.
    European journal of clinical pharmacology, 1975, Aug-14, Volume: 8, Issue:6

    Topics: Adult; Aged; Aging; Creatinine; Female; Half-Life; Humans; Injections, Intravenous; Kidney; Kidney Diseases; Kidney Function Tests; Kinetics; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged

1975
Effect of methotrexate treatment on the onset of autoimmune kidney disease in lupus mice.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:8

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Female; Kidney Diseases; Lupus Vulgaris; Male; Methotrexate; Mice; Mice, Inbred Strains

1992
How to improve the risk-benefit ratio of cyclosporin therapy for psoriasis.
    Clinical and experimental dermatology, 1992, Volume: 17, Issue:1

    Topics: Cyclosporine; Drug Therapy, Combination; Humans; Kidney Diseases; Methotrexate; Psoriasis; PUVA Therapy; Retinoids

1992
Low dose MTX and NSAID induced "mild" renal insufficiency and severe neutropenia.
    The Journal of rheumatology, 1991, Volume: 18, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; Methotrexate; Middle Aged; Neutropenia

1991
Ornithine decarboxylase induction in mouse kidney as indicator of renal damage. Differential nephrotoxic effect of anticancer antifolate drugs.
    Cancer letters, 1991, Volume: 59, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers; Enzyme Induction; Female; Folic Acid; Folic Acid Antagonists; Indomethacin; Kidney; Kidney Diseases; Methotrexate; Mice; Organ Size; Ornithine Decarboxylase; Quinazolines

1991
Raised plasma methotrexate concentrations following intrathecal administration in children with renal dysfunction.
    Leukemia, 1991, Volume: 5, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Female; Half-Life; Humans; Injections, Spinal; Kidney Diseases; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1991
Low-dose methotrexate and severe neutropenia in patients undergoing renal dialysis.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:7

    Topics: Agranulocytosis; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Methotrexate; Neutropenia; Renal Dialysis

1990
Severe renal toxicity due to intermediate-dose methotrexate.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:4

    Topics: Adult; Aged; Back Pain; Bicarbonates; Fluid Therapy; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouthwashes; Sodium; Sodium Bicarbonate; Stomatitis

1989
Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen.
    Lancet (London, England), 1986, Feb-01, Volume: 1, Issue:8475

    Topics: Adolescent; Adult; Aged; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ketoprofen; Kidney Diseases; Lymphoma; Male; Methotrexate; Middle Aged; Osteosarcoma; Phenylpropionates; Retrospective Studies; Time Factors

1986
Renal impairment following the combined use of high-dose methotrexate and procarbazine.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Humans; Kidney Diseases; Medulloblastoma; Methotrexate; Procarbazine; Vincristine

1988
The use of diamox in the sequential methotrexate-5-fluorouracil therapy of advanced gastrointestinal cancer.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Acetazolamide; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Gastrointestinal Neoplasms; Humans; Kidney Diseases; Methotrexate

1988
Renal toxicity with cumulative doses of cis-diamminedichloroplatinum-II in pediatric patients with osteosarcoma. Effect on creatinine clearance and methotrexate excretion.
    Cancer, 1987, May-01, Volume: 59, Issue:9

    Topics: Child; Cisplatin; Creatine; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Methotrexate; Osteosarcoma

1987
Urinary N-acetyl-beta-D-glucosaminidase and serum creatinine concentrations predict impaired excretion of methotrexate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:5

    Topics: Acetylglucosaminidase; Adolescent; Adult; Child; Cisplatin; Creatinine; Half-Life; Hexosaminidases; Humans; Kidney Diseases; Methotrexate; Osteosarcoma

1987
Iatrogenic drug toxicity.
    Monographs in pathology, 1985, Issue:26

    Topics: Acetaminophen; Age Factors; Amphotericin B; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Hemolysis; Humans; Isoniazid; Kidney Diseases; Methotrexate; Pharmaceutical Preparations; Probability; Time Factors

1985
[The treatment of disseminated lupus erythematosus. So-called immunosuppressive drugs].
    Schweizerische medizinische Wochenschrift, 1970, Feb-14, Volume: 100, Issue:7

    Topics: Adolescent; Antibodies, Antinuclear; Autoantibodies; Betamethasone; Female; Hepatitis; Humans; Immune Tolerance; Immunosuppressive Agents; Kidney Diseases; Lupus Erythematosus, Systemic; Melphalan; Methotrexate; Neutrophils; Prednisone; Splenectomy

1970
Monilial septicaemia in acute leukaemia. Successful treatment in a case complicated by acute uric acid nephropathy.
    The New Zealand medical journal, 1966, Volume: 65, Issue:401

    Topics: Acetazolamide; Adolescent; Amphotericin B; Candidiasis; Humans; Infectious Mononucleosis; Kidney Diseases; Leukemia; Male; Mercaptopurine; Methotrexate; Nystatin; Penicillins; Peripheral Nervous System Diseases; Prednisone; Rolitetracycline; Sepsis; Uric Acid

1966
Autoimmune disease.
    The Medical journal of Australia, 1969, Mar-29, Volume: 1, Issue:13

    Topics: Adolescent; Antibodies, Antinuclear; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Azathioprine; Child; Complement System Proteins; Corticosterone; Cyclophosphamide; Female; Fluorescent Antibody Technique; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunosuppressive Agents; Kidney Diseases; Lupus Erythematosus, Systemic; Lymphoid Tissue; Male; Methotrexate

1969
Proximal tubular hypertrophy in a case of acute leukemia of childhood: a study by microdissection.
    American journal of clinical pathology, 1970, Volume: 53, Issue:6

    Topics: Acute Disease; Child, Preschool; Humans; Hypertrophy; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Prednisone

1970
Treatment of acute leukemia with L-asparaginase--preliminary results on 84 cases.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Acute Disease; Asparaginase; Asparagine; Blood Coagulation Disorders; Cells, Cultured; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Daunorubicin; Humans; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver Function Tests; Methotrexate; Prednisone; Valine; Vincristine

1970
Chemically-induced renal hypertrophy in the rat.
    Biochemical pharmacology, 1968, Volume: 17, Issue:8

    Topics: Animals; DNA; Folic Acid; Hypertrophy; Kidney; Kidney Diseases; Male; Methotrexate; Organ Size; Pyridines; Pyrimidines; Rats; RNA; Triamterene; Ureteral Obstruction; Xanthopterin

1968
Renal toxicity of methotrexate.
    Cancer, 1969, Volume: 23, Issue:1

    Topics: Aged; Aminohippuric Acids; Blood Urea Nitrogen; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Humans; Inulin; Kidney; Kidney Diseases; Leiomyosarcoma; Leukocyte Count; Male; Methotrexate; Middle Aged; Stomach Neoplasms; Tongue Neoplasms

1969