methotrexate has been researched along with Hematologic Diseases in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (32.80) | 18.7374 |
| 1990's | 29 (23.20) | 18.2507 |
| 2000's | 39 (31.20) | 29.6817 |
| 2010's | 15 (12.00) | 24.3611 |
| 2020's | 1 (0.80) | 2.80 |
| Authors | Studies |
|---|---|
| Kataoka, H; Kondo, M; Makita, K; Mukai, M; Tomita, T; Tsuji, T | 1 |
| Lund, M; Melbye, M; Pasternak, B; Svanström, H | 1 |
| Duan, W; Kang, HL; Yang, SL; Zhao, Q | 1 |
| Bombardier, C; Katchamart, W; Ortiz, Z; Rader, T; Shea, B; Swinden, MV; Tanjong Ghogomu, E; Tugwell, P; Wells, GA | 1 |
| Chuang, H; Fanale, M; Fayad, L; Fowler, N; Hagemeister, FB; Kwak, LW; McLaughlin, P; Neelapu, S; Oki, Y; Orlowski, RZ; Ouzounian, ST; Rodriguez, MA; Romaguera, JE; Samaniego, F; Vega, F; Wang, M; Westin, JR; Younes, A | 1 |
| Aoki, H; Fujii, Y; Isogawa, M; Natsumeda, M; Ogura, R; Okada, M; Tsukamoto, Y; Yoshida, S | 1 |
| Chen, T; Du, Q; Huang, Y; Lin, X; Lu, Z; Song, C; Sun, C; Tao, Y; Tu, S; Wu, B | 1 |
| Frey, NV; Ganetsky, A; He, J; Hexner, EO; Hwang, WT; Loren, AW; Miano, TA; Porter, DL; Reshef, R; Shah, A | 1 |
| Hidaka, M; Hidaka, T; Kawakita, T; Migita, K; Mori, S; Tsuda, H; Ueki, Y; Yoshitama, T | 1 |
| Boice, J; Colombel, JF; Cornillie, F; D'Haens, G; Ghosh, S; Hommes, DW; Huang, Z; Huyck, S; Lindgren, S; Panes, J; Prantera, C; Reinisch, W | 1 |
| Paul, C; Prey, S | 1 |
| Habuchi, T; Horikawa, Y; Inoue, T; Kumazawa, T; Narita, S; Obara, T; Saito, M; Satoh, S; Tsuchiya, N; Yuasa, T | 1 |
| Gafter-Gvili, A; Paul, M; Raanani, P; Ram, R; Shpilberg, O; Yeshurun, M | 1 |
| Marrodán, L; Patiño-García, A; San-Julián, M; Sierrasesúmaga, L; Zalacaín, M | 1 |
| Choi, MK; Jun, HJ; Kim, K; Kim, KH; Kim, SJ; Kim, WS; Ko, YH; Lee, SY; Lim, DH | 1 |
| Chapman, PT; Frampton, C; James, J; O'Donnell, JL; Stamp, LK; White, DH | 1 |
| Salgo, R; Thaçi, D | 1 |
| Barba, P; Brunet, S; Carreras, E; Fernández-Avilés, F; Martínez, C; Martino, R; Piñana, JL; Rovira, M; Sierra, J; Sureda, A; Valcárcel, D | 1 |
| Bourré-Tessier, J; Haraoui, B | 1 |
| Bombardier, C; Bourré-Tessier, J; Bykerk, VP; Donka, T; Drouin, J; Haraoui, B; Katchamart, W; Leclerq, S; Mosher, DP; Pope, JE; Rohekar, G; Shojania, K; Thomson, J; Thorne, JC | 1 |
| Ambrosetti, A; Angrilli, F; Barbolini, E; Capodanno, I; Caracciolo, F; Carella, AM; Di Renzo, N; Federico, M; Galimberti, S; Ilariucci, F; Luminari, S; Merli, F; Petrini, M; Stelitano, C; Visco, C | 1 |
| Suzuki, Y | 1 |
| Chen, MG; Gastineau, DA; Gertz, MA; Inwards, DJ; Kumar, S; Lacy, MQ; Litzow, MR; Tefferi, A; Wolf, RC | 1 |
| Aldaz, A; Aquerreta, I; Giráldez, J; Sierrasesúmaga, L | 1 |
| Culine, S | 1 |
| Boiocchi, M; Corona, G; Innocenti, F; Mini, E; Russo, A; Sartor, F; Toffoli, G; Tumolo, S | 1 |
| Brufsky, A; Faul, C; Flickinger, J; Gerszten, K; Jacob, H; Kunschner, A; Vogel, V | 1 |
| COOPER, BA; LOWENSTEIN, L | 1 |
| Arzumanov, AS; Iamshanov, VA; Ivanov, SD; Khazova, TV; Korytova, LI | 1 |
| Malgarini, RB; Pimpinella, G | 1 |
| Campbell, M; Joannon, P; Oviedo, I; Tordecilla, J | 1 |
| Kautiainen, H; Kulman, I; Pincus, T; Sokka, T; Swearingen, C; Yazici, Y | 1 |
| Altundag, K; Atahan, L; Baltali, E; Cengiz, M; Erol, K; Guler, N; Onat, DA; Ozisik, Y; Sayek, I; Tekuzman, G | 1 |
| Bode, U; Buchen, S; Fleischhack, G; Hasan, C; Henze, G; Melton, RG; Ngampolo, D; Zoubek, A | 1 |
| Amabile, G; Capasso, I; D'Aiuto, G; De Maio, E; de Matteis, A; Di Maio, M; Elmo, M; Gravina, A; Labonia, V; Landi, G; Morrica, B; Nuzzo, F; Pacilio, C; Perrone, F; Rinaldo, M; Rossi, E | 1 |
| Sugii, S | 1 |
| Harten, P | 1 |
| Chayama, K; Endo, C; Hamada, S; Hashii, Y; Inagaki, J; Inoue, M; Kawa, K; Kishimoto, T; Miyamura, T; Nakano, T; Nomura, K; Okamura, T; Park, YD; Saito, I; Sakata, N; Sasabe, M; Sato, E; Sawada, A; Yasui, M; Yumura-Yagi, K | 1 |
| Brogan, K; Howard, J; Hudis, C; Hurria, A; Jakubowski, A; Norton, L; Panageas, KS; Pearce, C | 1 |
| Kosaki, K; Mori, T; Samejima, H; Sato, R; Shimada, H; Shimasaki, N; Takahashi, T; Tanigawara, Y; Torii, C; Yahagi, N; Yoshihara, H | 1 |
| Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE | 1 |
| Baldini, L; Balzarotti, M; Bernardi, M; Bobbio, F; Brandes, AA; Caligaris Cappio, F; Corazzelli, G; Dell'Oro, S; Ferreri, AJ; Foppoli, M; Ilariucci, F; Montanari, M; Picozzi, P; Ponzoni, M; Reni, M; Spina, M; Stelitano, C; Tosoni, A; Zaja, F | 1 |
| Costea, I; Graziani, A; Krajinovic, M; Laverdiere, C; Moghrabi, A | 1 |
| Bardi, A; Campioni, D; Caruso, A; Catozzi, L; De Mattei, M; Della Porta, M; Federici, F; Gemmati, D; Gilli, G; Mauro, E; Ongaro, A; Pellati, A; Scapoli, GL; Tognazzo, S | 1 |
| Aksakal, N; Citak, EC; Demirci, S; Karadeniz, C; Oguz, A; Okur, A; Okur, V; Uluoglu, O | 1 |
| Bafaloukos, D; Briasoulis, E; Dafni, U; Dimitrakakis, K; Dimopoulos, AM; Fountzilas, G; Gogas, H; Kalofonos, HP; Karanikiotis, C; Karina, M; Linardou, H; Makrantonakis, P; Markopoulos, C; Papadimitriou, C; Papakostas, P; Pectasides, D; Pisanidis, N; Polichronis, A; Samantas, E; Skarlos, D; Stathopoulos, GP; Tzorakoeleftherakis, E; Varthalitis, I; Xiros, N | 1 |
| Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T | 1 |
| Colozza, M; D'Aiuto, G; De Maio, E; de Matteis, A; De Placido, S; Di Rella, F; Gallo, C; Gori, S; Gravina, A; Labonia, V; Landi, G; Lauria, R; Morabito, A; Nuzzo, F; Pacilio, C; Perrone, F; Piccirillo, MC; Rossi, E; Signoriello, G; Thomas, R | 1 |
| Inamoto, Y; Kodera, Y; Kuwatsuka, Y; Miyamura, K; Murata, M; Naoe, T; Oba, T; Onizuka, M; Sugimoto, K; Terakura, S | 1 |
| Abella, E; Bastida, P; Bethencourt, C; Bueno, J; del Potro, E; Feliu, E; Fernández-Abellán, P; Grande, C; Heras, I; Oriol, A; Ortega, JJ; Parody, R; Ribera, JM; Sanz, MA; Tormo, M | 1 |
| Aroney, RS; Bell, DR; Fisher, RJ; Levi, JA | 1 |
| Coombes, RC; Ford, HT; Gazet, JC; Perez, DJ; Powles, TJ | 1 |
| Bertino, JR; Kowal, CD; Pitman, SW | 1 |
| Begg, CB; Carbone, PP | 1 |
| Kubota, K; Mizoguchi, H; Nomura, Y; Okada, M | 1 |
| Cadman, EC; Cross, J; Glick, JH; Horton, J; Taylor, SG | 1 |
| Bidlingmaier, F; Haas, RJ; Helmig, M; Janka, GE; Mack, R | 1 |
| Brower, M; Bunn, PA; Carney, DN; Cohen, MH; Eddy, J; Ihde, DC; Matthews, MJ; Minna, JD; Pelsor, FR | 1 |
| Alberts, DS; Borst, J; Hilgers, RD; Miles, NJ; Skipper, BE; Standefer, JC | 1 |
| Takaku, F | 1 |
| Gomez, GA; Han, T; Henderson, E; Moayeri, H; Naeher, C; Plager, J; Shimaoka, K; Stutzman, L | 1 |
| Goodman, TA; Polisson, RP | 1 |
| Igawa, M; Kadena, H; Ueda, M; Usui, T | 1 |
| Manganelli, P; Troise Rioda, W | 1 |
| Buchbinder, R; Champion, GD; Hall, S; Harkness, A; Lewis, D; Littlejohn, GO; Miller, MH; Ryan, PF; Sambrook, PN | 1 |
| Falk, M; Fridrik, MA; Haidinger, R; Hausmaninger, H; Klocker, J; Linkesch, W; Neubauer, M; Pont, J; Radaszkiewicz, T; Raudaschl, G; Schiller, L; Seewann, HL; Sill, H; Stöger, M | 1 |
| Aapro, M; Amadori, D; Bliss, JM; Chilvers, CE; Coombes, G; Coombes, RC; Espié, M; Ferreira, EP; Gambrosier, P; Marty, M; McArdle, C; Morvan, F; Pérez-López, FR; Richards, M; Vassilopoulos, P; Villar-Grimalt, A; Wils, J; Woods, EM | 1 |
| Mempel, K; Pfetsch, M; Reiter, A; Riehm, H; Schrappe, M; Schwab, G; Welte, K | 1 |
| Golding, PF; Hamilton, CR; Kerr, J; Mead, GM; Milne, AE; O'Callaghan, A; Simmonds, PD; Smartt, P; Sweetenham, JW; Whitehouse, JM | 1 |
| McKendry, RJ | 1 |
| Ashley, S; Chang, JC; Gregory, RK; Powles, TJ | 1 |
| Iitsuka, Y; Matsui, H; Seki, K; Sekiya, S | 1 |
| Benesch, M; Kerbl, R; Lackner, H; Oberbauer, R; Pakisch, B; Schwinger, W; Urban, C | 1 |
| Czaykowski, PM; Michael, M; Moore, MJ; Tannock, IF | 1 |
| Doggett, RS; Donnelly, BJ; Heney, NM; Kaufman, DS; Lee, WR; Murray, KJ; Perez, CA; Shipley, WU; Tester, WR; True, LD; Venner, PM; Winter, KA | 1 |
| Avanzini, P; Baldini, L; Brugiatelli, M; Carotenuto, M; Clò, V; Di Renzo, N; Dini, D; Federico, M; Gobbi, PG; Lombardo, M; Silingardi, V; Vallisa, D | 1 |
| Bielack, S; de Wit, M; Dürken, M; Erttmann, R; Jaburg, N; Kabisch, H; Kröger, N; Krüger, W; Löliger, C; Renges, H; Rüssmann, B; Stockschläder, M; Wacker-Backhaus, G; Zabelina, T; Zander, AR | 1 |
| Moher, D; Ortiz, Z; Shea, B; Suarez Almazor, M; Tugwell, P; Wells, G | 1 |
| Brzozowska, A; Mazurkiewicz, M; Szatkowska, L | 1 |
| Burstein, HJ; Winer, EP | 1 |
| Barta, U; Ständer, K; Wollina, U | 1 |
| Harris, E; Jackson, N; Jones, L; Mahendra, P; Paneesha, S | 1 |
| Amato, RJ; Daliani, D; Do, KA; Finn, L; Fizazi, K; Kim, J; Logothetis, CJ; Millikan, RE; Pagliaro, LC; Papandreou, CN; Prow, DM; Tu, SM; Wang, X | 1 |
| Chan, H; Evans, WE; Pratt, CB | 1 |
| Berkowitz, RS; Goldstein, DP | 1 |
| Tzortzatou, F | 1 |
| Bando, H; Nakamura, Y; Saito, S; Shintani, Y; Yokogoshi, Y | 1 |
| Anasetti, C; Appelbaum, FR; Bowden, RA; Deeg, HJ; Doney, K; Longton, G; Nash, RA; Pepe, MS; Pettinger, M; Storb, R | 1 |
| Mayall, B; Parkin, JD | 1 |
| Beex, LV; Hermus, AR; Mignolet, F; Nooy, MA; Pieters, GF; van Hoesel, QG | 1 |
| Dalesio, O; Durrant, KR; George, M; Guthrie, D; Lacave, AJ; Mangioni, C; Rotmenz, N; van der Burg, ME; Vermorken, JB | 1 |
| Greco, FA; Greer, JP; Hainsworth, JD; Johnson, DH; McMaster, ML; Wolff, SN | 1 |
| Faustini, M; Milani, A; Piva, L; Pizzocaro, G; Spino, E | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Osterlind, K; Pedersen, AG; Sörenson, S | 1 |
| Kienzer, H; Klocker, J; Pont, J; Prüger, J; Schumer, J | 1 |
| Allen, S; Bosworth, H; Budman, D; Lehrman, D; Lichtman, SM; Schulman, P; Vinciguerra, V; Weiselberg, L; Weiss, R | 1 |
| Ackerman, C; Goemaere, S; Mielants, H; Van der Straeten, C; Veys, EM | 1 |
| Ansari, R; Fisher, WB; Meyer, SC; Roth, BJ; Sledge, GW; Williams, SD | 1 |
| Bhardwaj, S; Holland, JF | 1 |
| Fraser, P; Weinblatt, ME | 1 |
| Guillet, G; Plantin, P; Saraux, A | 1 |
| Hanrahan, PS; Russell, AS; Scrivens, GA | 1 |
| Hansen, HS; Lindeløv, B | 1 |
| Sanders, JE | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, FR; Osterlind, K; Sørensson, S; Vindeløv, LL | 1 |
| Chamot, AM; Gerster, JC; Van Melle, G | 1 |
| Bajorin, D; Heelan, R; Kelsen, D | 1 |
| Fabian, CJ; Goldberg, RS; Griffin, BR; Hammond, N; Hynes, H; Livingston, RB; Rivkin, SE; Schulman, S; Tranum, BL | 1 |
| Cabanillas, F; Hagemeister, FB; McLaughlin, P; Riggs, S; Salvador, P; Tannir, N; Velasquez, WS | 1 |
| Barcos, M; Gomez, GA; Han, T; Henderson, ES | 1 |
| Bennett, JM; Carbone, PP; Cummings, F; Falkson, G; Kalish, LA; Olson, JE; Taylor, SG; Tormey, DC | 1 |
| Weinblatt, ME | 1 |
| Asbury, RF; Kao, AK; Muggia, FM; Wernz, JC | 1 |
| Freiha, FS; Hannigan, JF; Harker, WG; McWhirter, KM; Meyers, FJ; Palmer, JM; Shortliffe, LD; Torti, FM | 1 |
| Miyazaki, S; Nagayama, T; Take, H | 1 |
| Meister, H; Trux, F | 1 |
| Bauters, F; Goudemand, M; Lerche, B | 1 |
| Gailani, DS | 1 |
| Schwartz, RS; Skinner, MD | 1 |
| Weir, DG | 1 |
| Wong, VG | 1 |
| Bischof, B | 1 |
| Baker, H | 1 |
| Yoshino, T | 1 |
18 review(s) available for methotrexate and Hematologic Diseases
| Article | Year |
|---|---|
Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.
Topics: Abdominal Pain; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid; Folic Acid Antagonists; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leucovorin; Methotrexate; Nausea; Vomiting | 2013 |
Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Eruptions; Folic Acid; Gastrointestinal Diseases; Hematologic Diseases; Humans; Immunosuppressive Agents; Leucovorin; Liver Diseases; Methotrexate; Psoriasis; Randomized Controlled Trials as Topic | 2009 |
Prophylaxis regimens for GVHD: systematic review and meta-analysis.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Graft vs Host Disease; Hematologic Diseases; Humans; Immunosuppressive Agents; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Recurrence; Risk; Tacrolimus; Treatment Outcome | 2009 |
Treatment of moderate-to-severe plaque psoriasis.
Topics: Abnormalities, Drug-Induced; Alefacept; Antibodies, Monoclonal; Clinical Trials as Topic; Contraindications; Cyclosporine; Etanercept; Female; Fumarates; Hematologic Diseases; Humans; Hypertension; Immunoglobulin G; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Photochemotherapy; Pregnancy; Pregnancy Complications; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retinoids; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2009 |
Methotrexate drug interactions in the treatment of rheumatoid arthritis: a systematic review.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Databases, Factual; Drug Interactions; Hematologic Diseases; Humans; Methotrexate; Risk Factors; Trimethoprim, Sulfamethoxazole Drug Combination | 2010 |
Canadian recommendations for use of methotrexate in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Canada; Evidence-Based Medicine; Hematologic Diseases; Humans; Liver; Methotrexate; Patient Preference; Practice Guidelines as Topic; Rheumatology | 2010 |
[Gemcitabine and urogenital tumors].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cystectomy; Deoxycytidine; Doxorubicin; Female; Gemcitabine; Germinoma; Hematologic Diseases; Humans; Kidney Neoplasms; Male; Methotrexate; Organoplatinum Compounds; Patient Selection; Prostatic Neoplasms; Salvage Therapy; Treatment Outcome; Urinary Bladder Neoplasms; Urogenital Neoplasms; Vinblastine | 2002 |
[Adverse effects of DMARDs in treatment of rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases, Interstitial; Male; Methotrexate; Reproduction; Sulfasalazine | 2005 |
[Adverse effects of conventional DMARDs and biologic DMARDs].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate | 2007 |
Methotrexate: adverse reactions and major toxicities.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Hematologic Diseases; Humans; Lung Diseases; Methotrexate | 1994 |
[Weekly low-dose methotrexate in rheumatoid arthritis. Review of the literature].
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Interactions; Hematologic Diseases; Humans; Immune System Diseases; Interleukins; Leukocytes, Mononuclear; Lung Diseases; Methotrexate; Neutrophils | 1993 |
The remarkable spectrum of methotrexate toxicities.
Topics: Antirheumatic Agents; Bone Diseases; Central Nervous System; Digestive System; Hematologic Diseases; Homocysteine; Humans; Methotrexate; Rheumatoid Nodule | 1997 |
Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid; Folic Acid Antagonists; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leucovorin; Methotrexate | 2000 |
New combinations with Herceptin in metastatic breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Female; Fluorouracil; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Nitriles; Organoplatinum Compounds; Paclitaxel; Tamoxifen; Thiotepa; Trastuzumab; Treatment Outcome; Triazoles; Vinblastine; Vinorelbine | 2001 |
[Methotrexate in dermatology: current aspects].
Topics: Abnormalities, Drug-Induced; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Lung Diseases; Male; Methotrexate; Pregnancy; Skin Diseases | 1989 |
Toxicity of low dose methotrexate in rheumatoid arthritis.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases | 1985 |
Methotrexate in the treatment of psoriasis.
Topics: Abnormalities, Drug-Induced; Bone Marrow; Chemical and Drug Induced Liver Injury; Female; Hematologic Diseases; Humans; Kidney Diseases; Leucovorin; Liver; Methotrexate; Pregnancy; Psoriasis; Skin | 1972 |
Immunosuppressive therapy of immunoinflammatory diseases.
Topics: Abnormalities, Multiple; Abortion, Spontaneous; Collagen Diseases; Cyclophosphamide; Female; Gastrointestinal Diseases; Hematologic Diseases; Immune System Diseases; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Leukopenia; Liver Function Tests; Lymphoma; Mercaptopurine; Methotrexate; Nervous System Diseases; Pregnancy | 1974 |
34 trial(s) available for methotrexate and Hematologic Diseases
| Article | Year |
|---|---|
Prospective phase II study of rituximab with alternating cycles of hyper-CVAD and high-dose methotrexate with cytarabine for young patients with high-risk diffuse large B-cell lymphoma.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Hematologic Diseases; Humans; Kidney Diseases; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Risk; Rituximab; Thrombosis; Vincristine; Young Adult | 2013 |
Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Allografts; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Stem Cell Transplantation; Tacrolimus; Time Factors; Transplantation Conditioning | 2016 |
Rituximab plus HyperCVAD alternating with high dose cytarabine and methotrexate for the initial treatment of patients with mantle cell lymphoma, a multicentre trial from Gruppo Italiano Studio Linfomi.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Follow-Up Studies; Genetic Markers; Hematologic Diseases; Humans; Infections; Kaplan-Meier Estimate; Lymphoma, Mantle-Cell; Methotrexate; Middle Aged; Prospective Studies; Rituximab; Treatment Outcome; Vincristine; Young Adult | 2012 |
Pharmacodynamics of high-dose methotrexate in pediatric patients.
Topics: Adolescent; Adult; Algorithms; Antimetabolites, Antineoplastic; Area Under Curve; Child; Child, Preschool; Female; Fluorescence Polarization Immunoassay; Hematologic Diseases; Humans; Kidney Diseases; Linear Models; Logistic Models; Male; Methotrexate; Neoplasms; Predictive Value of Tests | 2002 |
High-dose methotrexate therapy of childhood acute lymphoblastic leukemia: lack of relation between serum methotrexate concentration and creatinine clearance.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chile; Creatine; Disease-Free Survival; Drug Monitoring; Female; Hematologic Diseases; Humans; Infant; Leucovorin; Male; Metabolic Clearance Rate; Methotrexate; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stomatitis | 2004 |
Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; gamma-Glutamyl Hydrolase; Hematologic Diseases; Humans; Infant; Male; Methotrexate; Middle Aged; Sepsis | 2005 |
MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Hematologic Diseases; Humans; Idarubicin; Life Tables; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Radiotherapy, Adjuvant; Remission Induction; Stroke; Survival Analysis; Thiotepa | 2006 |
Postoperative dose-dense sequential chemotherapy with epirubicin, paclitaxel and CMF in patients with high-risk breast cancer: safety analysis of the Hellenic Cooperative Oncology Group randomized phase III trial HE 10/00.
Topics: Adult; Aged; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Estrogens; Female; Fluorouracil; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Paclitaxel; Peripheral Nervous System Diseases; Tamoxifen | 2008 |
Weekly docetaxel versus CMF as adjuvant chemotherapy for elderly breast cancer patients: safety data from the multicentre phase 3 randomised ELDA trial.
Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Italy; Methotrexate; Patient Compliance; Taxoids; Treatment Outcome | 2008 |
Comparison of the results of the treatment of adolescents and young adults with standard-risk acute lymphoblastic leukemia with the Programa Español de Tratamiento en Hematología pediatric-based protocol ALL-96.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Hematologic Diseases; Humans; Hydrocortisone; Infant; Infections; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Treatment Outcome; Vincristine | 2008 |
Methotrexate and 5-fluorouracil in sequence in squamous head and neck cancer.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Gastrointestinal Diseases; Head and Neck Neoplasms; Hematologic Diseases; Humans; Methotrexate | 1983 |
Clinical trials and drug toxicity in the elderly. The experience of the Eastern Cooperative Oncology Group.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Neoplasms; Prognosis; Semustine | 1983 |
CEOP-IMVP-Dexa in the treatment of aggressive lymphomas: an Austrian multicenter trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexamethasone; Epirubicin; Etoposide; Feasibility Studies; Female; Folic Acid; Hematologic Diseases; Humans; Ifosfamide; Karnofsky Performance Status; Lymphoma, Non-Hodgkin; Male; Mesna; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prednisolone; Remission Induction; Risk Factors; Survival Rate; Vincristine | 1996 |
Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, epirubicin, and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: results of a randomized trial. The International Collab
Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Nausea; Premenopause; Regression Analysis; Survival Analysis; Vomiting | 1996 |
A randomized phase-III study of the efficacy of granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Münster Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Fever; Filgrastim; Gastrointestinal Diseases; Germany; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Ifosfamide; Infant; Infection Control; Life Tables; Male; Mercaptopurine; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Recombinant Proteins; Risk; Survival Analysis; Thioguanine; Vincristine; Vindesine | 1996 |
PACE BOM chemotherapy: a 12-week regimen for advanced Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphamide; Disease Progression; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Fertility; Follow-Up Studies; Hematologic Diseases; Hodgkin Disease; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisolone; Retreatment; Treatment Outcome; Vincristine | 1997 |
A randomised trial of six versus twelve courses of chemotherapy in metastatic carcinoma of the breast.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasm Metastasis; Palliative Care; Prospective Studies; Survival Rate; Vincristine | 1997 |
Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Deafness; Disease Progression; Disease-Free Survival; Etoposide; Follow-Up Studies; Glioma; Hearing Loss; Hematologic Diseases; Humans; Ifosfamide; Infections; Life Tables; Lomustine; Medulloblastoma; Methotrexate; Prognosis; Radiotherapy, Adjuvant; Remission Induction; Vincristine | 1998 |
Phase III trial of neoadjuvant chemotherapy in patients with invasive bladder cancer treated with selective bladder preservation by combined radiation therapy and chemotherapy: initial results of Radiation Therapy Oncology Group 89-03.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Invasiveness; Survival Analysis; Time Factors; Urinary Bladder Neoplasms; Vinblastine | 1998 |
Efficacy of two different ProMACE-CytaBOM derived regimens in advanced aggressive non-Hodgkin's lymphoma. Final report of a multicenter trial conducted by GISL.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Heart Diseases; Hematologic Diseases; Humans; Idarubicin; Italy; Karnofsky Performance Status; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Proportional Hazards Models; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 1998 |
Use of a five-agent GVHD prevention regimen in recipients of unrelated donor marrow.
Topics: Adolescent; Adult; Anti-Infective Agents; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematologic Diseases; Histocompatibility Testing; Humans; Immunoglobulin A; Immunoglobulin M; Immunosuppressive Agents; Infant; Male; Methotrexate; Metronidazole; Middle Aged; Transplantation, Homologous; Treatment Outcome | 1999 |
[Cisplatin and vinorelbine therapy of previously treated advanced breast cancer (preliminary studies)].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Disease Progression; Doxorubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Skin Neoplasms; Treatment Outcome; Vinblastine; Vinorelbine | 2001 |
Alternating dose-dense chemotherapy in patients with high volume disseminated non-seminomatous germ cell tumours.
Topics: Adolescent; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Cyclophosphamide; Dactinomycin; Disease-Free Survival; Doxorubicin; Etoposide; Gastrointestinal Diseases; Germinoma; Hematologic Diseases; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Peripheral Nervous System Diseases; Prognosis; Prospective Studies; Remission Induction; Seminoma; Survival Analysis; Survival Rate; Testicular Neoplasms; Treatment Outcome; Vincristine | 2002 |
Recovery from toxicity associated with high-dose methotrexate: prognostic factors.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dehydration; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Infant; Kidney Diseases; Kidney Function Tests; Leucovorin; Liver Diseases; Liver Function Tests; Male; Methotrexate; Neoplasms; Pleural Effusion; Prognosis; Time Factors; Vomiting | 1977 |
Methotrexate, vinblastine, adriamycin and cisplatin versus methotrexate and cisplatin in advanced urothelial cancer. A randomized study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Urologic Neoplasms; Vinblastine | 1991 |
Combination chemotherapy of limited-stage small-cell lung cancer. A controlled trial on 221 patients comparing two alternating regimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Vincristine | 1991 |
The efficacy and toxicity of a constant low dose of methotrexate as a treatment for intractable rheumatoid arthritis: an open prospective study.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Blood Sedimentation; Bone Marrow Diseases; C-Reactive Protein; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Kidney Failure, Chronic; Liver; Male; Methotrexate; Middle Aged; Prospective Studies | 1991 |
Methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic breast cancer. A phase II trial of the Hoosier Oncology Group.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Evaluation; Female; Hematologic Diseases; Humans; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Stomatitis; Survival Rate; Vinblastine | 1991 |
A pilot trial of TMM (thiotepa, mitoxantrone and methotrexate) chemotherapy for metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Mitoxantrone; Pilot Projects; Thiotepa | 1990 |
The superiority of combination chemotherapy including etoposide based on in vivo cell cycle analysis in the treatment of extensive small-cell lung cancer: a randomized trial of 288 consecutive patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Autopsy; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Random Allocation | 1987 |
Phase II trial of dichloromethotrexate in epidermoid carcinoma of the esophagus.
Topics: Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Drug Evaluation; Esophageal Neoplasms; Hematologic Diseases; Humans; Methotrexate; Middle Aged | 1986 |
Cyclophosphamide, vincristine, adriamycin, and prednisone (CHOP) with and without intermediate dose methotrexate for the treatment of non-Hodgkin's lymphomas of diffuse histology.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Hematologic Diseases; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Random Allocation; Vincristine | 1987 |
Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Fluorouracil; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy; Menopause; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Obesity; Prednisone; Prognosis; Random Allocation; Receptors, Estrogen; Risk; Tamoxifen | 1985 |
Toxicity of low dose methotrexate in rheumatoid arthritis.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infertility, Female; Infertility, Male; Kidney Diseases; Lung Diseases; Male; Methotrexate; Middle Aged; Neoplasms; Psoriasis; Random Allocation; Risk; Skin Diseases | 1985 |
74 other study(ies) available for methotrexate and Hematologic Diseases
| Article | Year |
|---|---|
Autopsy of a case of rheumatoid arthritis with severe bicytopoenia due to gelatinous transformation of the bone marrow.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Autopsy; Bone Marrow; Fatal Outcome; Female; Hematologic Diseases; Humans; Methotrexate; Severity of Illness Index | 2021 |
Concomitant use of low-dose methotrexate and NSAIDs and the risk of serious adverse events among patients with rheumatoid arthritis.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Denmark; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Registries | 2018 |
Efficacy of Combination Therapy with Actinomycin D and Methotrexate in the Treatment of Low-Risk Gestational Trophoblastic Neoplasia.
Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, Combination; Female; Gestational Trophoblastic Disease; Hematologic Diseases; Humans; Logistic Models; Methotrexate; Middle Aged; Neoplasm Staging; Oral Ulcer; Pregnancy; Prognosis; Treatment Outcome; Young Adult | 2019 |
Advantages of dose-dense methotrexate protocol for primary central nervous system lymphoma: comparison of two different protocols at a single institution.
Topics: Academies and Institutes; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Hematologic Diseases; Hospitals, University; Humans; Kaplan-Meier Estimate; Kidney Diseases; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Procarbazine; Remission Induction; Retrospective Studies; Treatment Outcome; Vincristine; Young Adult | 2013 |
[The outcome of thirteen patients with nonmalignant hematologic diseases treated with HLA haploidentical stem cell transplantation].
Topics: Anemia, Aplastic; Busulfan; Graft vs Host Disease; Hematologic Diseases; Histocompatibility; HLA Antigens; Humans; Incidence; Methotrexate; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2014 |
Factors Associated with Myelosuppression Related to Low-Dose Methotrexate Therapy for Inflammatory Rheumatic Diseases.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Female; Folic Acid; Hematologic Diseases; Humans; Hypoalbuminemia; Male; Methotrexate; Middle Aged; Neutropenia; Pancytopenia; Retrospective Studies; Rheumatic Diseases; Risk Factors; Serum Albumin | 2016 |
Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azathioprine; Crohn Disease; Demyelinating Diseases; Drug Substitution; Drug Therapy, Combination; Female; Gastrointestinal Agents; Hematologic Diseases; Humans; Immunosuppressive Agents; Infections; Infliximab; Infusions, Intravenous; Lymphoproliferative Disorders; Male; Mercaptopurine; Mesalamine; Methotrexate; Middle Aged; Mortality; Narcotics; Prednisone; Prospective Studies; Registries; Risk Factors; Sulfasalazine; Time Factors; Young Adult | 2017 |
[Combination therapy consisting of gemcitabine, docetaxel and carboplatin as a second-line chemotherapy for patients with MVAC-treated metastatic urothelial carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Cisplatin; Deoxycytidine; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Administration Schedule; Gemcitabine; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Retrospective Studies; Taxoids; Urologic Neoplasms; Vinblastine | 2008 |
Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression.
Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Case-Control Studies; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gastrointestinal Diseases; Genotype; Hematologic Diseases; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 2009 |
Treatment outcome of adult patients with Burkitt lymphoma: results using the LMB protocol in Korea.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Drug Evaluation; Etoposide; Female; Hematologic Diseases; Humans; Kaplan-Meier Estimate; Korea; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Sepsis; Treatment Outcome; Vincristine; Young Adult | 2009 |
Lack of association between elevated mean red cell volume and haematological toxicity in patients receiving long-term methotrexate for rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cross-Sectional Studies; Erythrocyte Volume; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neutropenia; Pancytopenia; Prospective Studies; Retrospective Studies; Time Factors; Young Adult | 2010 |
MTX or mycophenolate mofetil with CsA as GVHD prophylaxis after reduced-intensity conditioning PBSCT from HLA-identical siblings.
Topics: Adolescent; Adult; Aged; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Retrospective Studies; Siblings; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2010 |
[Anti-rheumatic drugs].
Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate | 2012 |
Omission of day +11 methotrexate after allogeneic bone marrow transplantation is associated with increased risk of severe acute graft-versus-host disease.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Drug Administration Schedule; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Male; Methotrexate; Recurrence; Retrospective Studies; Risk; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2002 |
Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; DNA Primers; Female; Genotype; Hematologic Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Platelet Count; Polymerase Chain Reaction; Polymorphism, Genetic | 2003 |
Concurrent sequencing of full-dose CMF chemotherapy and radiation therapy in early breast cancer has no effect on treatment delivery.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Drug Delivery Systems; Female; Fluorouracil; Follow-Up Studies; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Patient Satisfaction; Radiation Dosage | 2003 |
RELATIVE FOLATE DEFICIENCY OF ERYTHROCYTES IN PERNICIOUS ANEMIA AND ITS CORRECTION WITH CYANOCOBALAMIN.
Topics: Anemia; Anemia, Hypochromic; Anemia, Pernicious; Biological Assay; Blood Chemical Analysis; Chromatography; Erythrocytes; Folic Acid; Folic Acid Deficiency; Hematologic Diseases; Humans; Lactobacillus; Metabolism; Methotrexate; Vitamin B 12 | 1964 |
[Prognostication of hematotoxicity for radio- and chemotherapy in patients with breast cancer].
Topics: Adult; Aged; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Cyclophosphamide; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Prognosis; Radiotherapy, Adjuvant | 2003 |
Etanercept and methotrexate in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Hematologic Diseases; Humans; Immunoglobulin G; Methotrexate; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins | 2004 |
Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Monitoring; Female; Follow-Up Studies; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Risk Assessment; Treatment Failure | 2005 |
Neoadjuvant chemotherapy with cyclophosphamide, mitoxantrone, and 5-fluorouracil in locally advanced breast cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Causality; Chemotherapy, Adjuvant; Cisplatin; Comorbidity; Disease-Free Survival; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Survival Analysis; Turkey | 2005 |
Compliance and toxicity of adjuvant CMF in elderly breast cancer patients: a single-center experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Patient Compliance; Radiotherapy, Adjuvant; Retrospective Studies | 2005 |
[Reducing toxicity of methotrexate with folic acid].
Topics: Antirheumatic Agents; Clinical Trials as Topic; Drug Combinations; Folic Acid; Folic Acid Antagonists; Hematologic Diseases; Humans; Methotrexate; Rheumatic Diseases; Treatment Outcome | 2005 |
Unrelated donor bone marrow transplantation for 100 pediatric patients: a single institute's experience.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Disease-Free Survival; Drug Therapy, Combination; Female; Graft Rejection; Graft vs Host Disease; Hematologic Diseases; Humans; Infant; Japan; Male; Methotrexate; Methylprednisolone; Premedication; Retrospective Studies; Tacrolimus; Tissue Donors | 2005 |
Effect of creatinine clearance on patterns of toxicity in older patients receiving adjuvant chemotherapy for breast cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Creatinine; Cyclophosphamide; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Predictive Value of Tests; Retrospective Studies; Time Factors | 2005 |
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma.
Topics: Adolescent; Alleles; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Genetic Predisposition to Disease; Genetic Variation; Hematologic Diseases; Humans; Infant; Japan; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Stomatitis | 2006 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2007 |
Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia.
Topics: Child; Disease-Free Survival; Folic Acid; Folic Acid Antagonists; Hematologic Diseases; Humans; Liver; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2006 |
Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Doxorubicin; Female; Genotype; Hematologic Diseases; Humans; Kaplan-Meier Estimate; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mucositis; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prednisone; Risk; Survival Analysis; Treatment Outcome; Vincristine | 2007 |
Clinical characteristics and treatment results of pediatric B-cell non-Hodgkin lymphoma patients in a single center.
Topics: Adolescent; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Disease-Free Survival; Diuretics; Female; Fluid Therapy; Hematologic Diseases; Humans; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Leucovorin; Lymphoma, B-Cell; Male; Methotrexate; Mucositis; Neoplasm Proteins; Risk Assessment; Sodium Bicarbonate; Survival Analysis; Survival Rate; Treatment Outcome; Tumor Burden; Tumor Lysis Syndrome; Turkey; Vincristine | 2007 |
Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype.
Topics: Acute Disease; Adolescent; Adult; Female; Genotype; Graft vs Host Disease; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Living Donors; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Transplantation, Homologous | 2008 |
High-dose methotrexate with leucovorin rescue, vinblastine, and bleomycin with or without tamoxifen in metastatic renal cell carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Evaluation; Female; Hematologic Diseases; Humans; Kidney Neoplasms; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Random Allocation; Tamoxifen; Time Factors; Vinblastine | 1984 |
Mitomycin C, melphalan and methotrexate combination chemotherapy for palliation of disseminated breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Melphalan; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Palliative Care | 1984 |
Quantitative analysis of chromosomal G-bands in human hematopoietic disorders by methotrexate synchronization technique.
Topics: Anemia; Bone Marrow; Cell Cycle; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cytarabine; Hematologic Diseases; Humans; Karyotyping; Kinetics; Leukemia; Metaphase; Methotrexate | 1984 |
Sequential methotrexate and 5-FU in CMFP (cyclophosphamide, methotrexate, 5-FU, and prednisone) therapy for breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Liver Neoplasms; Lung Neoplasms; Methotrexate; Middle Aged; Prednisone; Recurrence | 1984 |
Prolonged methotrexate infusions in children with acute leukemia in relapse and in remission and with medulloblastoma. Pharmacokinetics, toxicity and clinical results.
Topics: Actuarial Analysis; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Hematologic Diseases; Humans; Infusions, Parenteral; Injections, Spinal; Kinetics; Leukemia, Lymphoid; Medulloblastoma; Methotrexate; Recurrence | 1984 |
High-dose methotrexate with leucovorin rescue in patients with unresectable non-small cell carcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Creatinine; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Leucovorin; Lung Neoplasms; Male; Methotrexate; Middle Aged | 1983 |
Phase II and pharmacokinetic study of high-dose methotrexate in the treatment of advanced gynecologic malignancy. A Southwest Oncology Group Trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Genital Neoplasms, Female; Hematologic Diseases; Humans; Kidney Diseases; Kinetics; Leucovorin; Methotrexate; Middle Aged; Nausea; Time Factors | 1984 |
[Acute renal failure and hematologic diseases].
Topics: Acute Kidney Injury; Antineoplastic Agents; Child; Disseminated Intravascular Coagulation; Hematologic Diseases; Humans; Leukemia; Lymphoma; Methotrexate; Middle Aged | 1983 |
Combinations of methotrexate (COP or CHOP) in the treatment of previously untreated and treated lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leucovorin; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1982 |
Association between patient characteristics and treatment history, and toxicity associated with methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) for advanced urothelial cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Kidney; Liver; Male; Methotrexate; Middle Aged; Urologic Neoplasms; Vinblastine | 1994 |
Methotrexate therapy in rheumatoid arthritis: a life table review of 587 patients treated in community practice.
Topics: Adult; Arthritis, Rheumatoid; Community Medicine; Female; Gastrointestinal Diseases; Glucocorticoids; Hematologic Diseases; Humans; Life Tables; Male; Methotrexate; Middle Aged; Professional Practice; Rheumatology | 1993 |
Comparison of chemotherapies with methotrexate, VP-16 and actinomycin-D in low-risk gestational trophoblastic disease. Remission rates and drug toxicities.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin; Dactinomycin; Drug Administration Schedule; Etoposide; Female; Hematologic Diseases; Humans; Methotrexate; Pregnancy; Remission Induction; Risk Factors; Trophoblastic Neoplasms; Uterine Neoplasms | 1998 |
Adjuvant chemotherapy for high-risk urothelial transitional cell carcinoma: the Princess Margaret Hospital experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Disease-Free Survival; Female; Follow-Up Studies; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Salvage Therapy; Urinary Bladder Neoplasms; Vinblastine | 1998 |
Toxicity of methotrexate treatment in psoriasis and psoriatic arthritis--short- and long-term toxicity in 104 patients.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Central Nervous System Diseases; Child; Drug Interactions; Enzyme Inhibitors; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Time Factors; Transaminases | 2001 |
Burkitt's lymphoma: single-centre experience with modified BFM protocol.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infections; Lymphoma, AIDS-Related; Male; Mercaptopurine; Methotrexate; Prednisone; Recurrence; Remission Induction; Treatment Outcome; Vincristine | 2002 |
Methotrexate with citrovorum factor rescue for nonmetastatic gestational trophoblastic neoplasms.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin; Drug Administration Schedule; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leucovorin; Liver; Methotrexate; Middle Aged; Pregnancy; Risk; Trophoblastic Neoplasms; Uterine Neoplasms | 1979 |
Cytochemical demonstration of dihydrofolate reductase in leukaemia and other haematological diseases.
Topics: Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Methotrexate; Multiple Myeloma; Polycythemia Vera; Tetrahydrofolate Dehydrogenase | 1977 |
Serum parathyroid hormone-related protein concentrations in patients with hematologic malignancies or solid tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasms; Osmolar Concentration; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Prednisolone; Proteins; Vincristine | 1992 |
Acute graft-versus-host disease: analysis of risk factors after allogeneic marrow transplantation and prophylaxis with cyclosporine and methotrexate.
Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Methotrexate; Multivariate Analysis; Retrospective Studies; Risk Factors; Sex Factors; Survival Analysis; Tissue Donors; Transplantation, Homologous; Whole-Body Irradiation | 1992 |
Haemopoietic toxicity and low-dose methotrexate.
Topics: Hematologic Diseases; Hematopoiesis; Humans; Methotrexate | 1992 |
Dose intensity of chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil in the elderly with advanced breast cancer.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Creatinine; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate | 1992 |
Bleomycin, methotrexate, and CCNU in advanced inoperable squamous cell carcinoma of the vulva: a phase II study of the EORTC Gynaecological Cancer Cooperative Group (GCCG).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Female; Hematologic Diseases; Humans; Lomustine; Lung Diseases; Methotrexate; Middle Aged; Vulvar Neoplasms | 1990 |
Effective treatment of small-noncleaved-cell lymphoma with high-intensity, brief-duration chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hematologic Diseases; Humans; Leucovorin; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prednisone; Prognosis; Survival Rate; Vincristine | 1991 |
Carboplatin, methotrexate and vinblastin (Carbo-MV) for advanced urothelial cancer. A phase II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Transitional Cell; Combined Modality Therapy; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasm Staging; Radiotherapy; Survival Rate; Urologic Neoplasms; Vinblastine | 1991 |
Adjuvant therapy of stage II breast cancer treated with CMFVP, radiation therapy and VATH following lumpectomy. A pilot trial.
Topics: Adjuvants, Pharmaceutic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Esthetics; Female; Fluorouracil; Fluoxymesterone; Hematologic Diseases; Humans; Lymphatic Metastasis; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Prednisone; Radiotherapy; Survival Rate; Thiotepa; Vinblastine; Vincristine | 1991 |
Elevated mean corpuscular volume as a predictor of hematologic toxicity due to methotrexate therapy.
Topics: Aged; Arthritis, Rheumatoid; Blood; Blood Cell Count; Female; Forecasting; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Survival Analysis | 1989 |
Prospective long term follow-up of methotrexate therapy in rheumatoid arthritis: toxicity, efficacy and radiological progression.
Topics: Aged; Arthritis, Rheumatoid; Blood Cell Count; Follow-Up Studies; Hematologic Diseases; Humans; Methotrexate; Middle Aged; Prospective Studies; Radiography; Severity of Illness Index; Time Factors | 1989 |
The effect of sequential methotrexate and 5-fluorouracil in patients with recurrent head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Drug Administration Schedule; Female; Fluorouracil; Head and Neck Neoplasms; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prognosis | 1989 |
Bone marrow transplantation as treatment of hematologic disease.
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Combined Modality Therapy; Female; Graft vs Host Disease; Hematologic Diseases; HLA Antigens; Humans; Infections; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Culture Test, Mixed; Methotrexate; Tissue Donors; Whole-Body Irradiation | 1986 |
[Low-dose oral methotrexate in the treatment of rheumatoid polyarthritis].
Topics: Adult; Aged; Alopecia; Arthritis, Rheumatoid; Blood Sedimentation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Time Factors | 1988 |
Combination chemotherapy and systemic irradiation consolidation for poor prognosis breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hematologic Diseases; Humans; Methotrexate; Prednisone; Prognosis; Vinblastine; Whole-Body Irradiation | 1987 |
MIME chemotherapy (methyl-GAG, ifosfamide, methotrexate, etoposide) as treatment for recurrent Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Female; Hematologic Diseases; Hematuria; Hodgkin Disease; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Mitoguazone | 1987 |
Mitomycin and methotrexate: negative experience in untreated colorectal carcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Rectal Neoplasms | 1985 |
Cisplatin, methotrexate, and vinblastine (CMV): an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract. A Northern California Oncology Group study.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Creatinine; Dehydration; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Nausea; Neoplasm Metastasis; Neoplasm Recurrence, Local; Urologic Neoplasms; Vinblastine | 1985 |
[Experimental study on antineoplastic agents causing hematopoietic diseases].
Topics: Animals; Antineoplastic Agents; Bleomycin; Dactinomycin; Daunorubicin; Erythrocyte Count; Hematologic Diseases; Hematopoietic System; Leukocyte Count; Methotrexate; Mice; Vincristine | 1972 |
[Immature cell panmyelosis].
Topics: Acid Phosphatase; Adult; Antibiotics, Antineoplastic; Asparaginase; Blood Transfusion; Bone Marrow Examination; Daunorubicin; Drug Combinations; Esterases; Glucuronidase; Hematologic Diseases; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Male; Megakaryocytes; Methotrexate; Peroxidases; Prednisolone; Spleen; Staining and Labeling; Thrombocytopenia; Vincristine | 1973 |
[Leukemic meningitis. Statistics of 33 cases].
Topics: Electroencephalography; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate | 1970 |
Pseudoleukemia during recovery from methotrexate toxicity in psoriasis.
Topics: Adult; Female; Hematologic Diseases; Humans; Leukemia; Methotrexate; Psoriasis | 1972 |
The pathogenesis of folic acid deficiency in man.
Topics: Adolescent; Adult; Aged; Alcoholism; Anemia, Macrocytic; Animals; Anticonvulsants; Celiac Disease; Child; Diet; Female; Folic Acid; Folic Acid Deficiency; Hematologic Diseases; Humans; Inflammation; Liver; Male; Metabolic Diseases; Methotrexate; Neoplasms; Pregnancy | 1974 |
Immunosuppressive therapy of ocular inflammatory diseases.
Topics: Adolescent; Adult; Behcet Syndrome; Chemical and Drug Induced Liver Injury; Child; Corneal Transplantation; Cyclophosphamide; Endophthalmitis; Eye Diseases; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hypersensitivity, Delayed; Immunity; Male; Methotrexate; Middle Aged; Ophthalmia, Sympathetic; Orbit; Pneumonia, Viral; Transplantation Immunology; Uveitis, Anterior | 1969 |
[Drug therapy in hemoblastosis].
Topics: Antineoplastic Agents; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Multiple Myeloma; Polycythemia Vera; Prednisone; Vincristine; Waldenstrom Macroglobulinemia | 1968 |
Intermittent high dose oral methotrexate therapy in psoriasis.
Topics: Adult; Aged; Aspirin; Ataxia; Colitis; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Stevens-Johnson Syndrome; Time Factors; Vomiting | 1970 |
The clinical and experimental studies on the metabolism of folic acid using tritiated folic acid. 3. Plasma clearance in man and organ distribution in rat following intravenous administration of tritiated folic acid.
Topics: Acute Disease; Animals; Body Weight; Bone Marrow; Carbon Tetrachloride; Chronic Disease; Folic Acid; Hematologic Diseases; Humans; Injections, Intravenous; Kidney; Leukemia; Liver; Liver Diseases; Methotrexate; Rats; Spleen; Tritium | 1968 |