Page last updated: 2024-08-25

methotrexate and Heart Diseases

methotrexate has been researched along with Heart Diseases in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's4 (18.18)18.2507
2000's8 (36.36)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fikry, EM; Gad, AM; Hassan, WA1
Arcari, A; Centurioni, R; Evangelista, A; Freilone, R; Ladetto, M; Liberati, AM; Luminari, S; Massidda, S; Merli, F; Musuraca, G; Nassi, L; Patti, C; Pavone, V; Peli, A; Pulsoni, A; Re, A; Salvi, F; Spina, M; Stelitano, C; Tani, M; Tucci, A; Volpetti, S; Zanni, M1
Castadot, P; Chargari, C; Di Leo, A; Magné, N; Philippson, C; Van Houtte, P1
Grier, HE; Janeway, KA1
EGGERS, O1
Adams, AE; Curiel, C; Drews, R; Falchuk, KR; Kadin, ME; Kupper, TS; Zwicker, J1
de Groot, K; Gause, A; Gross, WL; Hellmich, B; Metzler, C1
Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE1
Kukacka, J; Prusa, R; Sedlacek, P1
Benucci, M; Manfredi, M; Sulla, A1
Biller, H; Brooks, S; Holland, JF; Ohnuma, T; Plasse, TF; Saponaro, E1
Aisner, J; Cortes, E; Glidewell, OJ; Kennedy, BJ; Leone, LA; Perloff, M; Silver, RT; Tormey, DC; Weinberg, VE; Weiss, RB1
Golbey, RB; Lynch, G; Magill, GB; Sordillo, P1
Beaufort-Krol, GC; Bink-Boelkens, MT; Elzenga, NJ; Kamps, WA; Kengen, RA; Postma, A; Schasfoort-van Leeuwen, MJ; Schraffordt koops, H1
Karakiulakis, G; Paradelis, AG; Pispirigos, K1
Avanzini, P; Baldini, L; Brugiatelli, M; Carotenuto, M; Clò, V; Di Renzo, N; Dini, D; Federico, M; Gobbi, PG; Lombardo, M; Silingardi, V; Vallisa, D1
Burstein, HJ; Winer, EP1
Chilcote, RR; Kadin, ME; Kjeldsberg, C; Krailo, MD; Meadows, AT; Morse, M; Siegel, SE; Sposto, R; Steinherz, PG; Termuhlen, AM1
Chahinian, AP; Holland, JF; Jaffrey, IS; Mandel, EM; Teirstein, AS1
Jaffe, N1
Buzdar, AU; Forman, AD; Frye, DK; Holmes, FA; Hortobagyi, GN; Newton, LK; Raber, MN; Theriault, RL; Walters, RS1
Auclerc, G; Bernard, J; Boiron, M; Bussel, A; Delobel, J; Dresch, C; Flandrin, G; Gemon, MF; Izrael, V; Jacquillat, C; Loisel, JP; Najean, Y; Rain, D; Schaison, G; Seligmann, M; Tanzer, J; Weil, M; Weisgerber, C1

Reviews

4 review(s) available for methotrexate and Heart Diseases

ArticleYear
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects.
    The Lancet. Oncology, 2010, Volume: 11, Issue:7

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; Hearing Loss; Heart Diseases; Humans; Ifosfamide; Infertility; Kidney Diseases; Methotrexate; Neoplasms, Second Primary; Neurotoxicity Syndromes; Osteosarcoma; Survivors

2010
Cardiac engagement in multicentric reticulohistiocytosis: report of a case with fatal outcome and literature review.
    Internal and emergency medicine, 2008, Volume: 3, Issue:2

    Topics: Anti-Inflammatory Agents; Cyclophosphamide; Fatal Outcome; Female; Heart Diseases; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive Agents; Methotrexate; Methylprednisolone; Tumor Necrosis Factor-alpha

2008
New combinations with Herceptin in metastatic breast cancer.
    Oncology, 2001, Volume: 61 Suppl 2

    Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Female; Fluorouracil; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Nitriles; Organoplatinum Compounds; Paclitaxel; Tamoxifen; Thiotepa; Trastuzumab; Treatment Outcome; Triazoles; Vinblastine; Vinorelbine

2001
Late side effects of treatment: skeletal, genetic, central nervous system, and oncogenic.
    Pediatric clinics of North America, 1976, Volume: 23, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antineoplastic Agents; Busulfan; Carcinogens; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Child; Female; Heart Diseases; Humans; Lung Diseases; Male; Menstruation Disturbances; Mercaptopurine; Methotrexate; Neoplasms; Neoplasms, Radiation-Induced; Pregnancy; Radiotherapy; Urinary Bladder Diseases

1976

Trials

7 trial(s) available for methotrexate and Heart Diseases

ArticleYear
Bleomycin, vinblastine and dacarbazine combined with nonpegylated liposomal doxorubicin (MBVD) in elderly (≥70 years) or cardiopathic patients with Hodgkin lymphoma: a phase-II study from Fondazione Italiana Linfomi (FIL).
    Leukemia & lymphoma, 2019, Volume: 60, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Carmustine; Combined Modality Therapy; Female; Heart Diseases; Hodgkin Disease; Humans; Male; Methotrexate; Methylprednisolone; Neoplasm Staging; Prognosis; Recurrence; Remission Induction; Survival Analysis; Teniposide; Treatment Outcome

2019
Churg Strauss syndrome--successful induction of remission with methotrexate and unexpected high cardiac and pulmonary relapse ratio during maintenance treatment.
    Clinical and experimental rheumatology, 2004, Volume: 22, Issue:6 Suppl 36

    Topics: Adolescent; Adult; Aged; Churg-Strauss Syndrome; Drug Therapy, Combination; Female; Heart Diseases; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prednisolone; Recurrence; Remission Induction; Respiratory Tract Infections

2004
No effect of high-doses-methotrexate treatment on serum cardiac troponin I levels in children.
    Pediatric hematology and oncology, 2006, Volume: 23, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Female; Heart Diseases; Humans; Immunoassay; Male; Methotrexate; Troponin I

2006
A comparison of intermittent vs. continuous and of adriamycin vs. methotrexate 5-drug chemotherapy for advanced breast cancer. A Cancer and Leukemia Group B study.
    American journal of clinical oncology, 1984, Volume: 7, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart Diseases; Humans; Leukopenia; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Prednisone; Random Allocation; Time Factors; Vincristine

1984
Efficacy of two different ProMACE-CytaBOM derived regimens in advanced aggressive non-Hodgkin's lymphoma. Final report of a multicenter trial conducted by GISL.
    Haematologica, 1998, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Heart Diseases; Hematologic Diseases; Humans; Idarubicin; Italy; Karnofsky Performance Status; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Prognosis; Proportional Hazards Models; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine

1998
Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group.
    Medical and pediatric oncology, 2001, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Prednisone; Recurrence; Stomatitis; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine

2001
Phase II trial of taxol, an active drug in the treatment of metastatic breast cancer.
    Journal of the National Cancer Institute, 1991, Dec-18, Volume: 83, Issue:24

    Topics: Adult; Aged; Agranulocytosis; Alkaloids; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Doxorubicin; Drug Evaluation; Female; Heart Diseases; Humans; Methotrexate; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Peripheral Nervous System Diseases; Remission Induction; Soft Tissue Neoplasms; Thrombocytopenia

1991

Other Studies

11 other study(ies) available for methotrexate and Heart Diseases

ArticleYear
Bone marrow and adipose mesenchymal stem cells attenuate cardiac fibrosis induced by methotrexate in rats.
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:11

    Topics: Adipose Tissue; Animals; Apoptosis; Bone Marrow Cells; Cholesterol; Fibrosis; Heart Diseases; Male; Mesenchymal Stem Cell Transplantation; Methotrexate; Myocardium; NF-kappa B; Oxidative Stress; Rats, Wistar; Triglycerides

2017
Special focus on cardiac toxicity of different sequences of adjuvant doxorubicin/docetaxel/CMF regimens combined with radiotherapy in breast cancer patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 90, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chi-Square Distribution; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Heart Diseases; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Pilot Projects; Prospective Studies; Radiotherapy Dosage; Taxoids; Treatment Outcome

2009
[Effects of the new cardiac drug "cynosid comp." in daily practise].
    Therapie der Gegenwart, 1954, Volume: 93, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Convallaria; Cyclophosphamide; Heart Diseases; Methotrexate; Plants; Prednisone; Vincristine

1954
Aggressive cutaneous T-cell lymphomas after TNFalpha blockade.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Crohn Disease; Cyclophosphamide; Cytomegalovirus Infections; Diagnosis, Differential; Disease Progression; Fatal Outcome; Female; Gastritis; Gastrointestinal Hemorrhage; Heart Diseases; Humans; Lymphoma, T-Cell; Male; Methotrexate; Prednisone; Skin Neoplasms; Tumor Necrosis Factor-alpha; Vincristine

2004
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine

2007
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
    Cancer, 1984, Feb-15, Volume: 53, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Heart Diseases; Humans; Infusions, Parenteral; Lung Diseases; Male; Methotrexate; Middle Aged; Prognosis

1984
Combination chemotherapy of advanced sarcomas in adults with "CYOMAD" (S7).
    Cancer, 1982, Nov-01, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dacarbazine; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Heart Diseases; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Nausea; Sarcoma; Vincristine; Vomiting

1982
Late cardiotoxicity after treatment for a malignant bone tumor.
    Medical and pediatric oncology, 1996, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Bleomycin; Body Surface Area; Bone Neoplasms; Child; Cyclophosphamide; Dactinomycin; Dilatation, Pathologic; Doxorubicin; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart; Heart Diseases; Heart Rate; Humans; Male; Methotrexate; Middle Aged; Myocardium; Radionuclide Angiography; Stroke Volume; Survivors; Ventricular Dysfunction, Left

1996
Evaluation of cardiac subacute toxicity of epirubicin, chlorambucil, cisplatin, methotrexate and a homo-aza-steroid ester with antitumor activity in rats using serum biochemical parameters.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Aspartate Aminotransferases; Body Weight; Chlorambucil; Cisplatin; Creatine Kinase; Epirubicin; Heart Diseases; Isoenzymes; L-Lactate Dehydrogenase; Methotrexate; Rats

1997
MACC (methotrexate, adriamycin, cyclophosphamide and CCNU) in advanced lung cancer.
    Cancer, 1979, Volume: 43, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Eruptions; Drug Therapy, Combination; Female; Heart Diseases; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Thrombocytopenia

1979
Combination therapy in 130 patients with acute lymphoblastic leukemia (protocol 06 LA 66-Paris).
    Cancer research, 1973, Volume: 33, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Central Nervous System Diseases; Child; Child, Preschool; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Heart; Heart Diseases; Humans; Infant; Leukemia, Lymphoid; Male; Meninges; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Sex Factors; Time Factors; Vincristine

1973